CA1046882A - Inhaler - Google Patents
InhalerInfo
- Publication number
- CA1046882A CA1046882A CA211,781A CA211781A CA1046882A CA 1046882 A CA1046882 A CA 1046882A CA 211781 A CA211781 A CA 211781A CA 1046882 A CA1046882 A CA 1046882A
- Authority
- CA
- Canada
- Prior art keywords
- capsule
- inhaler
- body portion
- piece
- mouth
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Expired
Links
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
- A61M15/00—Inhalators
- A61M15/0028—Inhalators using prepacked dosages, one for each application, e.g. capsules to be perforated or broken-up
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
- A61M11/00—Sprayers or atomisers specially adapted for therapeutic purposes
- A61M11/001—Particle size control
- A61M11/003—Particle size control by passing the aerosol trough sieves or filters
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
- A61M15/00—Inhalators
- A61M15/0028—Inhalators using prepacked dosages, one for each application, e.g. capsules to be perforated or broken-up
- A61M15/003—Inhalators using prepacked dosages, one for each application, e.g. capsules to be perforated or broken-up using capsules, e.g. to be perforated or broken-up
- A61M15/0033—Details of the piercing or cutting means
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
- A61M2202/00—Special media to be introduced, removed or treated
- A61M2202/06—Solids
- A61M2202/064—Powder
Abstract
ABSTRACT OF THE DISCLOSURE
The present invention provides an inhaler for the ad-ministration of powdered substances, comprising a body portion having a chamber for receiving a capsule containing powdered substances, piercing devices on the said body portion operable to perforate a capsule in the capsule chamber, and air intake passages communicating with the capsule chamber and positioned in such a manner that air drawn therethrough when inhaling air through an inhaling passage leading from the chamber imparts a rotary and shaking motion to a capsule in the capsule chamber.
The present invention provides an inhaler for the ad-ministration of powdered substances, comprising a body portion having a chamber for receiving a capsule containing powdered substances, piercing devices on the said body portion operable to perforate a capsule in the capsule chamber, and air intake passages communicating with the capsule chamber and positioned in such a manner that air drawn therethrough when inhaling air through an inhaling passage leading from the chamber imparts a rotary and shaking motion to a capsule in the capsule chamber.
Description
The present invention relates to inhalers, and partic-ularly to an inhaler for the administration of powdered medica-ments.
According to the present invention, there is provided an inhaler for the administration of powdered substances com-prising a body portion having a chamber for receiving a capsule containing powdered substances, piercing devices on the said body portion operably to perforate a capsule in the capsuIe cham-ber, and air intake passages communicating with the capsule cham-ber and positioned in such a manner that air drawn therethroughwhen inhaling air through an inhaling passage leading from the chamber imparts a rotary and shaking motion to a capsule in the capsule chamber.
In a particular embodiment of the present invention ~-~
the inhaler is constructed in two main parts, a body portion of the inhaler and a tubular portion or mouth-piece: these two portions are connected to each other by a suitable releasable connection to allow access to the interior of the body portion so as to place a capsule containing the substance for inhalation in position in the capsule chamber. Following perforation of the capsule by the piercing devices, inhalation by the patient through the tubular portion or mouth-piece causes the powder to be drawn out of the capsule and entrained in the inhaled air.
Preferably the air intakes are positioned such that intake air passes tangentially into the capsule chamber. In the preferred embodiment of the invention the capsule chamber has an elongate recess in the bottom wall thereof, in which recess the capsule in the chamber rests when the inhaler is not in use, and the air intake passages are positioned in such a way that a cap-sule is drawn from the recess into the capsule chamber by theair passing through the capsule chamber from the intakes to the -- 1 - ~ :
q~ :
~ . ., ~ . . ~ . .
~046882 inhalation passage upon inhalation. The inhaler of the present invention is convenient and simple to use, of constant efficiency thereby ensuring a consistent dosage, and of small size.
The body portion and tubular portion are preferably pivoted together and in the preferred embodiment this is effected by means of a pivot pin the axis of which is parallel to the axis of the tubular portion but which is eccentrically placed on one side thereof to allow disengagement or locking by a simple rota- ~-tion of one portion with respect to the other about an axis par-allel to the axis of the tubular portion of the inhaler. -Preferably the piercing devices comprise movable push-buttons each carrying a set of elongate spikes positioned to en-ter a capsule in the recess in the capsule chamber, to effect perforation thereof, upon depression of a push button. In the preferred embodiment there are two such push buttons each being maintained in a normal position by four independent springs, and held in place by shoulders on the body portion which engage cooperating shoulders on each push-button. Each of the push-buttons supports four elongate metal spikes. Perforation of a capsule in the recess in the capsule chamber is thus simply ef-fected by a simple pressure on one or both of the push buttons.
The shape of the recess in the bottom wall of the cap-sule chamber is preferably substantially the same as that of a conventional medicament capsule, the recess being generally rec-tangular with rounded ends. Preferably the spikes or pins of the piercing devices are coaxial with the recess so that a cap-sule is perforated at its ends. The capsule chamber is prefer-ably circular so that a pierced capsule is caused to rotate solely by the tangential intake air upon inhalation. The in-take air also acts to draw the capsule out of the recess uponinhalation so thatoperation is effectively automatic. The diameter of the capsule chamber is slightly larger than the length of a conventional medicament capsule so that there is a small clearance between the chamber and the ends of the capsule as it rotates, this causes a shaking of the capsule as it strikes against the cylindrical wall of the capsule chamber, thereby ~-urging the powder out from the capsule and causing it to be mixed with the intake air upon inhalation.
The tubular portion of the inhaler consists essentially of a circular section pipe having at one end a base supporting an abutment stop for locating the inhaler body. The base of the tubular portion forms, when the parts of the inhaler are assem-bled together, the upper part of the capsule chamber and has a slightly concave surface for facilitating the rotation of a cap-sule. At the opening of the inhalation passage of the tubular portion there is a grating, suitably dimensioned to optimize the air/powdered substance ratio.
One embodiment of the invention will now be more par-ticularly described, by way of example, with reference to the accompanying drawings, in which:-Figure 1 is an axial section of the tubular portion of an inhaler formed as an embodiment of the invention, the tu-bular portion forming the mouth-piece of the inhaler;
Figure 2 is a plan view of the mouth-piece shown in Figure l;
Figure 3 is a side view of three elements forming ~ -a spring-lock device for holding the mouth-piece and a body portion of the inhaler together;
Figure 4 is an underplan view of the body portion of the inhaler;
Figure 5 is an axial section of the body portion of the inhaler;
Figure 6 is a plan view of the body portion of the inhaler;
Figure 7 is a side view of the body portion of the in-haler, seen in the direction of the arrow A of Figure 5;
Figure 8 is a sectional view of a push button forming a part of the body portion of Figures 4 to 7;
Figure 9 is an end view, seen in the direction of the arrow B of the push button of Figure 8;
Figure 10 is a sectional view taken on the line X-X
of Figure 9;
Figure 11 is an axial sectional view of an assembled inhaler;
Figure 12 is an axial partially sectioned view similar to that of Figure 11, showing the inhaler with a cap in position;
and Figure 13, is a side view seen in the direction of the arrow C, of the inhaler with the cap in position of figure 12.
Referring now to the drawings, the inhaler shown comprises a body portion 21 and a tubular portion or mouth-piece 22. The mouthpiece 22 has an enlarged basal end 23 which engages over the upper face of the body portion. The mouthpiece 22 is connected to the body portion 21 by means of a pivot pin 3 pro-jecting from the basal portion 23 of the mouthpieee 22, which engages in a hole 13 in the body portion 21. The pivot pin 3 and hole 13 are aligned with one anobher and eccentric with relation to the longitudinal axis of the mouthpiece 22 and body portion 21. At the end of the pivot pin 3 is a lateral projection 3a.
The hole l3 has a lateral enlargement 13a and at the lower end thereof is formed with an enlarged section 13b. The lateral projection 3a of the pivot pin 3 passes down the lateral part 13a of the hole 13 upon insertion of the pin 3 into the hole 13 and, upon relative rotation of the body portion 21 and the mouth- ::
piece 22 this lateral projection 3a is moved out of register with the lateral part 13a of the hole 13 and into engagement with the shoulders at the end thereof formed by the enlargement 13_. The position of the lateral projection 3a and the lateral part 13_ is, in each case, such that the mouthpiece 22 and body portion 21 can be relatively rotated about the axis of the pivot pin 3 and hole 13 between a position in which the basal part 23 of the 10 mouthpiece 22 is in register with the upper face of the body por- .
tion 21, and a position where a chamber 10 in the body portion 21 is exposed without bringing the lateral portion 3_ of the pivot pin 3 into register with the lateral part 13a of the hole 13 so that, in use of the inhaler, the two portions 21 and 22 can remain fixed to one another, but the two portions may be se-parated from one another entirely if desired by relative rotation of the two portions to bring the cooperating parts 3a and 13a into register.
The body portion 21 of the inhaler is formed, as men-tioned above, with a chamber 10 in the lower wall of which there is an elongate recess 9 which has substantially the same shape as a conventional medicament capsule, as can be seen clearly in Figure 6. There are two recesses 12, 12' in the upper face of -the body portion 21 which communicate tangentially with the re-cess 10, which latter has a circular cross section. When the mouthpiece 22 and the body portion 21 of the inhaler are closed together the lower face of the basal portion 23 of the mouthpiece 22 closes the recess 10 to define a capsule chamber. Similarly, the recesses 12, 12' are closed by the basal portion 23 of the mouthpiece 22 to form air inlets to the capsule chamber 10.
At the lower end of the inhalation passage defined by . . - , the mouthpiece 22 there is secured a grating 1 which prevents a capsule in the capsule chamber 10 from being drawn up the mouth-piece upon inhalation. There is thus open communication between the inhalation passage of the mouthpiece 22, the capsule chamber 10 and the air intakes 12 and 12'.
Figure 3 illustrates a suitable form of latching device for holding the mouthpiece 22 and body portion 21 in the closed ~-position. As will be seen from Figure 1 the basal portion 23 of the mouthpiece 22 has a projection 2 on the side thereof opposite the pivot pin 3, which projection is L-shape when viewed in the direction of the arrow D of Figure 1. The L-shape projection 2 of the basal portion 23 of the mouthpiece 22 engages in an L-shape recess 24 in the upper part of the body portion 21 and is held in position by a latching device illustrated in Figure 3.
The latching device comprises a plunger 4 having a convexly cur-ved end, a compression spring 5 and a plug 6. These elements are housed in a bore 25 in the body portion 21, which bore opens into the lower face of the L-shape recess 24. The plunger 4 has a shoulder 4a which engages against a corresponding shoulder 25a near the upper end of the bore 25 to determine the maximum amount by which the convexly curved end of the plunger 4 can project from the opening into the L- shaped recess 24. When the mouthpiece 22 is rotated to the locked position the projection 2 extends into the recess 24 and displaces the plunger 4 downwardly against the action of the compression spring 5 which thus acts to lightly latch the projection 2 in place in the recess 24 thereby holding the inhaler portions 22 and the 21 together in the closed posi-tion.
In line with the end of the capsule recess 9 in the bottom of the recess 10 are located two push buttons 26 which carry four sharpened metal pins 14 which project inwardly towards the capsule recess 9. The body portion 21 is formed with two rectangular section galleries 7, 7' which have openings 8, 8' .-aligned with the end of the capsule recess 9. The two push but- .
tons 26 have pairs of shoulders 15, I5' which are located against the rim of the openings 8, 8' in the wall of the body portion 21 and held in position by four springs which engage in respective recesses 16, 16' in the push buttons 26. The inner wall of the .
galleries 7, 7' between the galleries themselves and the capsule recess 9 are provided with four openings 11, 11' aligned with the sharpened metal pins 14. Pressure applied to the push buttons 26 to compress the biasing springs which locate them in position urges the sharpened metal pins through the openings 11, 11' and into the capsule recess 9. When a capsule is positioned in the .
recess 9 it is held against movement by the fact that the recess 9 is only slightly larger than the capsule itself, and thus the sharpened metal pins 14 penetrate the two ends of the capsule perforating this and permitting the powdered medicament to pass out through these perforations after the push buttons 26 have -.-been released.
In operation of the inhaler the mouthpiece 22 and body portion 21 are relatively rotated about the pivot pin 3 to expose :
the recess 10 and a capsule is dropped into position into the .
capsule recess 9.
The mouthpiece 22 and body portion 21 are then closed until the projection 2 engages in the recess 24 and is latched in position by the plunger 4. The push buttons 26 are then de-pressed either individually or together to perforate the ends of the capsule in the capsule recess 9. Administration of the powdered medicament can then take place simply by inhaling through the mouthpiece 22 which can be applied either to the mouth or to the nostril. The rush of air through the inlets 12, 12' upon inhalation causes a vortex in the capsule chamber 10 due to the fact that the inlets 12 and 12' are positioned substantially tangentially with respect to the circular section capsule chamber 10. The vortex in the capsule chamber 10 lifts the capsule out from the capsule recess 9 and causes this to spin rapidly about the longitudinal axis of the inhaler. Because the length of the capsule is slightly less than the diameter of the capsule chamber 10 there are repeated impacts between the ends of the capsule and the side wall of the chamber 10 which causes powdered medicaments from within the capsule to be drawn out through the perforations in the ends of the capsule, this being assisted by the spinning motion of the capsule itself, and the powder is entrained with the air passing through the grating 1 and along the inhalation passage of the mouthpiece 22.
According to the present invention, there is provided an inhaler for the administration of powdered substances com-prising a body portion having a chamber for receiving a capsule containing powdered substances, piercing devices on the said body portion operably to perforate a capsule in the capsuIe cham-ber, and air intake passages communicating with the capsule cham-ber and positioned in such a manner that air drawn therethroughwhen inhaling air through an inhaling passage leading from the chamber imparts a rotary and shaking motion to a capsule in the capsule chamber.
In a particular embodiment of the present invention ~-~
the inhaler is constructed in two main parts, a body portion of the inhaler and a tubular portion or mouth-piece: these two portions are connected to each other by a suitable releasable connection to allow access to the interior of the body portion so as to place a capsule containing the substance for inhalation in position in the capsule chamber. Following perforation of the capsule by the piercing devices, inhalation by the patient through the tubular portion or mouth-piece causes the powder to be drawn out of the capsule and entrained in the inhaled air.
Preferably the air intakes are positioned such that intake air passes tangentially into the capsule chamber. In the preferred embodiment of the invention the capsule chamber has an elongate recess in the bottom wall thereof, in which recess the capsule in the chamber rests when the inhaler is not in use, and the air intake passages are positioned in such a way that a cap-sule is drawn from the recess into the capsule chamber by theair passing through the capsule chamber from the intakes to the -- 1 - ~ :
q~ :
~ . ., ~ . . ~ . .
~046882 inhalation passage upon inhalation. The inhaler of the present invention is convenient and simple to use, of constant efficiency thereby ensuring a consistent dosage, and of small size.
The body portion and tubular portion are preferably pivoted together and in the preferred embodiment this is effected by means of a pivot pin the axis of which is parallel to the axis of the tubular portion but which is eccentrically placed on one side thereof to allow disengagement or locking by a simple rota- ~-tion of one portion with respect to the other about an axis par-allel to the axis of the tubular portion of the inhaler. -Preferably the piercing devices comprise movable push-buttons each carrying a set of elongate spikes positioned to en-ter a capsule in the recess in the capsule chamber, to effect perforation thereof, upon depression of a push button. In the preferred embodiment there are two such push buttons each being maintained in a normal position by four independent springs, and held in place by shoulders on the body portion which engage cooperating shoulders on each push-button. Each of the push-buttons supports four elongate metal spikes. Perforation of a capsule in the recess in the capsule chamber is thus simply ef-fected by a simple pressure on one or both of the push buttons.
The shape of the recess in the bottom wall of the cap-sule chamber is preferably substantially the same as that of a conventional medicament capsule, the recess being generally rec-tangular with rounded ends. Preferably the spikes or pins of the piercing devices are coaxial with the recess so that a cap-sule is perforated at its ends. The capsule chamber is prefer-ably circular so that a pierced capsule is caused to rotate solely by the tangential intake air upon inhalation. The in-take air also acts to draw the capsule out of the recess uponinhalation so thatoperation is effectively automatic. The diameter of the capsule chamber is slightly larger than the length of a conventional medicament capsule so that there is a small clearance between the chamber and the ends of the capsule as it rotates, this causes a shaking of the capsule as it strikes against the cylindrical wall of the capsule chamber, thereby ~-urging the powder out from the capsule and causing it to be mixed with the intake air upon inhalation.
The tubular portion of the inhaler consists essentially of a circular section pipe having at one end a base supporting an abutment stop for locating the inhaler body. The base of the tubular portion forms, when the parts of the inhaler are assem-bled together, the upper part of the capsule chamber and has a slightly concave surface for facilitating the rotation of a cap-sule. At the opening of the inhalation passage of the tubular portion there is a grating, suitably dimensioned to optimize the air/powdered substance ratio.
One embodiment of the invention will now be more par-ticularly described, by way of example, with reference to the accompanying drawings, in which:-Figure 1 is an axial section of the tubular portion of an inhaler formed as an embodiment of the invention, the tu-bular portion forming the mouth-piece of the inhaler;
Figure 2 is a plan view of the mouth-piece shown in Figure l;
Figure 3 is a side view of three elements forming ~ -a spring-lock device for holding the mouth-piece and a body portion of the inhaler together;
Figure 4 is an underplan view of the body portion of the inhaler;
Figure 5 is an axial section of the body portion of the inhaler;
Figure 6 is a plan view of the body portion of the inhaler;
Figure 7 is a side view of the body portion of the in-haler, seen in the direction of the arrow A of Figure 5;
Figure 8 is a sectional view of a push button forming a part of the body portion of Figures 4 to 7;
Figure 9 is an end view, seen in the direction of the arrow B of the push button of Figure 8;
Figure 10 is a sectional view taken on the line X-X
of Figure 9;
Figure 11 is an axial sectional view of an assembled inhaler;
Figure 12 is an axial partially sectioned view similar to that of Figure 11, showing the inhaler with a cap in position;
and Figure 13, is a side view seen in the direction of the arrow C, of the inhaler with the cap in position of figure 12.
Referring now to the drawings, the inhaler shown comprises a body portion 21 and a tubular portion or mouth-piece 22. The mouthpiece 22 has an enlarged basal end 23 which engages over the upper face of the body portion. The mouthpiece 22 is connected to the body portion 21 by means of a pivot pin 3 pro-jecting from the basal portion 23 of the mouthpieee 22, which engages in a hole 13 in the body portion 21. The pivot pin 3 and hole 13 are aligned with one anobher and eccentric with relation to the longitudinal axis of the mouthpiece 22 and body portion 21. At the end of the pivot pin 3 is a lateral projection 3a.
The hole l3 has a lateral enlargement 13a and at the lower end thereof is formed with an enlarged section 13b. The lateral projection 3a of the pivot pin 3 passes down the lateral part 13a of the hole 13 upon insertion of the pin 3 into the hole 13 and, upon relative rotation of the body portion 21 and the mouth- ::
piece 22 this lateral projection 3a is moved out of register with the lateral part 13a of the hole 13 and into engagement with the shoulders at the end thereof formed by the enlargement 13_. The position of the lateral projection 3a and the lateral part 13_ is, in each case, such that the mouthpiece 22 and body portion 21 can be relatively rotated about the axis of the pivot pin 3 and hole 13 between a position in which the basal part 23 of the 10 mouthpiece 22 is in register with the upper face of the body por- .
tion 21, and a position where a chamber 10 in the body portion 21 is exposed without bringing the lateral portion 3_ of the pivot pin 3 into register with the lateral part 13a of the hole 13 so that, in use of the inhaler, the two portions 21 and 22 can remain fixed to one another, but the two portions may be se-parated from one another entirely if desired by relative rotation of the two portions to bring the cooperating parts 3a and 13a into register.
The body portion 21 of the inhaler is formed, as men-tioned above, with a chamber 10 in the lower wall of which there is an elongate recess 9 which has substantially the same shape as a conventional medicament capsule, as can be seen clearly in Figure 6. There are two recesses 12, 12' in the upper face of -the body portion 21 which communicate tangentially with the re-cess 10, which latter has a circular cross section. When the mouthpiece 22 and the body portion 21 of the inhaler are closed together the lower face of the basal portion 23 of the mouthpiece 22 closes the recess 10 to define a capsule chamber. Similarly, the recesses 12, 12' are closed by the basal portion 23 of the mouthpiece 22 to form air inlets to the capsule chamber 10.
At the lower end of the inhalation passage defined by . . - , the mouthpiece 22 there is secured a grating 1 which prevents a capsule in the capsule chamber 10 from being drawn up the mouth-piece upon inhalation. There is thus open communication between the inhalation passage of the mouthpiece 22, the capsule chamber 10 and the air intakes 12 and 12'.
Figure 3 illustrates a suitable form of latching device for holding the mouthpiece 22 and body portion 21 in the closed ~-position. As will be seen from Figure 1 the basal portion 23 of the mouthpiece 22 has a projection 2 on the side thereof opposite the pivot pin 3, which projection is L-shape when viewed in the direction of the arrow D of Figure 1. The L-shape projection 2 of the basal portion 23 of the mouthpiece 22 engages in an L-shape recess 24 in the upper part of the body portion 21 and is held in position by a latching device illustrated in Figure 3.
The latching device comprises a plunger 4 having a convexly cur-ved end, a compression spring 5 and a plug 6. These elements are housed in a bore 25 in the body portion 21, which bore opens into the lower face of the L-shape recess 24. The plunger 4 has a shoulder 4a which engages against a corresponding shoulder 25a near the upper end of the bore 25 to determine the maximum amount by which the convexly curved end of the plunger 4 can project from the opening into the L- shaped recess 24. When the mouthpiece 22 is rotated to the locked position the projection 2 extends into the recess 24 and displaces the plunger 4 downwardly against the action of the compression spring 5 which thus acts to lightly latch the projection 2 in place in the recess 24 thereby holding the inhaler portions 22 and the 21 together in the closed posi-tion.
In line with the end of the capsule recess 9 in the bottom of the recess 10 are located two push buttons 26 which carry four sharpened metal pins 14 which project inwardly towards the capsule recess 9. The body portion 21 is formed with two rectangular section galleries 7, 7' which have openings 8, 8' .-aligned with the end of the capsule recess 9. The two push but- .
tons 26 have pairs of shoulders 15, I5' which are located against the rim of the openings 8, 8' in the wall of the body portion 21 and held in position by four springs which engage in respective recesses 16, 16' in the push buttons 26. The inner wall of the .
galleries 7, 7' between the galleries themselves and the capsule recess 9 are provided with four openings 11, 11' aligned with the sharpened metal pins 14. Pressure applied to the push buttons 26 to compress the biasing springs which locate them in position urges the sharpened metal pins through the openings 11, 11' and into the capsule recess 9. When a capsule is positioned in the .
recess 9 it is held against movement by the fact that the recess 9 is only slightly larger than the capsule itself, and thus the sharpened metal pins 14 penetrate the two ends of the capsule perforating this and permitting the powdered medicament to pass out through these perforations after the push buttons 26 have -.-been released.
In operation of the inhaler the mouthpiece 22 and body portion 21 are relatively rotated about the pivot pin 3 to expose :
the recess 10 and a capsule is dropped into position into the .
capsule recess 9.
The mouthpiece 22 and body portion 21 are then closed until the projection 2 engages in the recess 24 and is latched in position by the plunger 4. The push buttons 26 are then de-pressed either individually or together to perforate the ends of the capsule in the capsule recess 9. Administration of the powdered medicament can then take place simply by inhaling through the mouthpiece 22 which can be applied either to the mouth or to the nostril. The rush of air through the inlets 12, 12' upon inhalation causes a vortex in the capsule chamber 10 due to the fact that the inlets 12 and 12' are positioned substantially tangentially with respect to the circular section capsule chamber 10. The vortex in the capsule chamber 10 lifts the capsule out from the capsule recess 9 and causes this to spin rapidly about the longitudinal axis of the inhaler. Because the length of the capsule is slightly less than the diameter of the capsule chamber 10 there are repeated impacts between the ends of the capsule and the side wall of the chamber 10 which causes powdered medicaments from within the capsule to be drawn out through the perforations in the ends of the capsule, this being assisted by the spinning motion of the capsule itself, and the powder is entrained with the air passing through the grating 1 and along the inhalation passage of the mouthpiece 22.
Claims (18)
PROPERTY OR PRIVILEGE IS CLAIMED ARE DEFINED AS FOLLOWS:
1. An inhaler for powdered medicaments comprising:
A. an elongated mouth-piece comprising a coaxially disposed inhalation passage;
B. a body portion comprising:
1. a chamber which is adapted to receive a capsule containing said medicaments and which is open communication with said inhalation passage, and 2. an air intake passage which is tangentially disposed to said chamber;
C. a pivot means, for pivotably connecting said mouth-piece and said body portion, comprising:
1. a hole within said body portion which is eccentrically disposed with respect to said chamber, and 2. a pivot pin which:
a. fits rotatably within said hole so that said pin and said hole are aligned when said pin and said hole are in register, b. has a pivot-pin axis which is parallel to the axis of said mouth-piece, and c. is attached to and eccentrically disposed on one side of said mounth-piece to allow disengagement or locking by a simple rotation about said pivot-pin axis of said body portion with respect to said mouth-piece;
D. a latching means for releasably securing said mouth-piece and said body portion when pivoted into register; and E. a capsule-piercing means on said body portion for selectively perforating said capsule, whereby said medicaments are released when air is drawn into said air intake passage and swirled about within said chamber.
a. fits rotatably within said hole so that said pin and said hole are aligned when said pin and said hole are in register, b. has a pivot-pin axis which is parallel to the axis of said mouth-piece, and c. is attached to and eccentrically disposed on one side of said mounth-piece to allow disengagement or locking by a simple rotation about said pivot-pin axis of said body portion with respect to said mouth-piece;
D. a latching means for releasably securing said mouth-piece and said body portion when pivoted into register; and E. a capsule-piercing means on said body portion for selectively perforating said capsule, whereby said medicaments are released when air is drawn into said air intake passage and swirled about within said chamber.
2. The inhaler of claim 1 wherein a lateral projection is attached to said pin at the end thereof and said hole has an axially disposed enlarged section, which is adapted for slidingly receiving said lateral projection, and an annular enlargement at the end thereof which is adapted to receive and retain said lateral projection when said pivot pin is rotated.
3. The inhaler of claim 1 wherein said latching means comprises an L-shaped projection, which is attached to said mouth-piece and projects outwardly toward said body portion and in the direction of said pivoting, and an L-shaped recess in said body portion which is adapted to receive said L-shaped projection when said mouth-piece and said body portion are in register.
4. The inhaler of claim 3 wherein said latching means further comprises a plunger having a convexly curved end and a compression spring which fit slideably within a longitudinally disposed bore within said body portion and communicating with said L-shaped recess, said plunger being adapted to project into said L-shaped recess and be biasedly depressed by said L-shaped projection
5. The inhaler of claim 1 wherein said chamber is cylindrical and comprises an elongated recess in an end wall thereof, said elongated recess being only slightly larger than said capsule.
6. The inhaler of claim 5 wherein said-capsule-piercing means is attached to said body portion and comprises a sharpened pin which is adapted to pass through an opening into said elongated recess.
7. An inhaler for administering powdered medicaments, comprising:
A. a mouth-piece, comprising:
1. an ellipsoidal tubular portion, having a major axis in cross section, with a coaxially disposed inhalation passage therein, 2. an enlarged basal end which is attached to said tubular portion, 3. a pivot pin, having two ends, which:
a. is rigidly attached at one end of said two ends to said basal end and eccentrically disposed thereon on one side of said tubular portion, b. has a pivot-pin axis which is disposed in parallel to the axis of said tubular portion, and c. has a rigidly attached lateral projection which is disposed at the other of said two ends, 4. an L-shaped projection which:
a. is rigidly attached at one end to said basal end along one side thereof, and b. has on the other end thereof a rigidly attached latching lug which projects laterally but obliquely toward said major axis; and 5.a grating attached to said tubular portion and across said inhalation passage;
B.a body portion, comprising:
1. an upper face which engages said basal end when said mouth-piece and said body portion are assembled, 2. a circular recess in said upper face, having tangentially disposed narrow recesses in communication therewith, 3. an elongated recess, disposed in said circular recess, which is adapted for receiving a capsule containing said powdered medicaments, 4. a hole which:
a. is disposed eccentrically to said axis of said tubular portion, b. has an elongated lateral enlargement in the perimeter thereof that accomodates said lateral projection when said mouth-piece and said tubular portion are revolved to and past a loading postion which exposes said chamber, c. extends from said upper face into said body portion for a distance equalling the distance along said pivot pin from said basal end face to said lateral projection; and d. terminates in an enlarged annular section which accommo-dates said lateral projection as it revolves around said pivot-pin axis while said mouth-piece and said body portion relatively revolve about said pivot-pin axis, 5. an L-shaped recess which:
a.is disposed along one side of said body portion and is laterally open, b. is obliquely disposed to said elongated recess, and c. has a laterally projecting latching slot into which said latching lug revolvingly fits when said body portion and said mouth-piece are mutually revolved from said loading position to an operating position in which said circular recess is aligned with said tubular portion; and C. a selectively operable capsule-piercing means for perforating said capsule, whereby said capsule is stored in sealed condition while said inhaler is in said operating position and said medica-ments are released after said capsule is pierced and air is drawn into said narrow recesses and swirled about within said chamber.
A. a mouth-piece, comprising:
1. an ellipsoidal tubular portion, having a major axis in cross section, with a coaxially disposed inhalation passage therein, 2. an enlarged basal end which is attached to said tubular portion, 3. a pivot pin, having two ends, which:
a. is rigidly attached at one end of said two ends to said basal end and eccentrically disposed thereon on one side of said tubular portion, b. has a pivot-pin axis which is disposed in parallel to the axis of said tubular portion, and c. has a rigidly attached lateral projection which is disposed at the other of said two ends, 4. an L-shaped projection which:
a. is rigidly attached at one end to said basal end along one side thereof, and b. has on the other end thereof a rigidly attached latching lug which projects laterally but obliquely toward said major axis; and 5.a grating attached to said tubular portion and across said inhalation passage;
B.a body portion, comprising:
1. an upper face which engages said basal end when said mouth-piece and said body portion are assembled, 2. a circular recess in said upper face, having tangentially disposed narrow recesses in communication therewith, 3. an elongated recess, disposed in said circular recess, which is adapted for receiving a capsule containing said powdered medicaments, 4. a hole which:
a. is disposed eccentrically to said axis of said tubular portion, b. has an elongated lateral enlargement in the perimeter thereof that accomodates said lateral projection when said mouth-piece and said tubular portion are revolved to and past a loading postion which exposes said chamber, c. extends from said upper face into said body portion for a distance equalling the distance along said pivot pin from said basal end face to said lateral projection; and d. terminates in an enlarged annular section which accommo-dates said lateral projection as it revolves around said pivot-pin axis while said mouth-piece and said body portion relatively revolve about said pivot-pin axis, 5. an L-shaped recess which:
a.is disposed along one side of said body portion and is laterally open, b. is obliquely disposed to said elongated recess, and c. has a laterally projecting latching slot into which said latching lug revolvingly fits when said body portion and said mouth-piece are mutually revolved from said loading position to an operating position in which said circular recess is aligned with said tubular portion; and C. a selectively operable capsule-piercing means for perforating said capsule, whereby said capsule is stored in sealed condition while said inhaler is in said operating position and said medica-ments are released after said capsule is pierced and air is drawn into said narrow recesses and swirled about within said chamber.
8. The inhaler of claim 7 which further comprises a cover having a generally oval cross-section with a major axis coinciding with said major axis of said ellipsoidal tubular portion and a pair of oppositely disposed side flaps which cover said narrow recesses when said cover is placed over said mouth-piece.
9. In an inhaler for administering powdered medicaments from a selectively pierced capsule, said inhaler having a tubular portion with a coaxially disposed inhalation passage therein and a body portion with an elongated recess for depositing said capsule therein, the improvement comprising:
A. pivot means for mutually revolving said tubular portion and said body portion from a closed operating position, in which said elong-ated recess is aligned with said passage and protectively covered by said tubular portion, to an open loading position, in which said elongated recess is exposed for depositing said capsule and further from said open loading position to a separating position, in which said tubular portion and said body portion are axially movable apart; B. a retaining means for maintaining said body portion and said tubular portion in revolvable relationship while mutually revolving from said opening position to said separating position; C. a joining-and-separating means, attached to said pivot means for permitting said tubular portion and said body portion to be axially moved apart in endwise sliding relationship while said inhaler is in said separating position; D. a latch means for revolvingly engaging said body portion and said tubular portion in said operating position; and E. an air inlet means, comprising narrow recesses in said body portion, for admitting air into said inhaler in said operating position and for permit-ting visual inspection and cleaning of said narrow recesses when said inhaler is in said loading position.
A. pivot means for mutually revolving said tubular portion and said body portion from a closed operating position, in which said elong-ated recess is aligned with said passage and protectively covered by said tubular portion, to an open loading position, in which said elongated recess is exposed for depositing said capsule and further from said open loading position to a separating position, in which said tubular portion and said body portion are axially movable apart; B. a retaining means for maintaining said body portion and said tubular portion in revolvable relationship while mutually revolving from said opening position to said separating position; C. a joining-and-separating means, attached to said pivot means for permitting said tubular portion and said body portion to be axially moved apart in endwise sliding relationship while said inhaler is in said separating position; D. a latch means for revolvingly engaging said body portion and said tubular portion in said operating position; and E. an air inlet means, comprising narrow recesses in said body portion, for admitting air into said inhaler in said operating position and for permit-ting visual inspection and cleaning of said narrow recesses when said inhaler is in said loading position.
10. The improvement in the inhaler of claim 9 wherein said pivot means comprises a pivot pin which is rigidly attached at its inner end to said tubular portion and a hole which extends from its outer end into said body portion and further comprises eccentrically disposing said pivot pin on said tubular portion and eccentrically disposing said hole in said body portion so that said pivot pin and said hole fit slidingly and rotatingly and are coaxially aligned.
11. The improvement in the inhaler of claim 10 wherein said retaining means comprises a lateral projection, disposed at the outer end of said pivot pin and extending laterally beyond said hole, and a lateral enlargement, disposed at the inner end of said hole, which accommodates revolving movement of said lateral projection while said tubular portion and said body portion are being mutually revolved from said operating position to and through said loading position and to said joining-and-separating position and which prevents said endwise sliding,
12. The improvement in the inhaler of claim 11 wherein said joining-and-separating means comprises, in combination, said lateral projection and an elongated lateral enlargement of said hole which slidingly fits said lateral projection, said lateral projection and said lateral enlargement being in register only when said tubular portion and said body portion are in said separating position and being more than 180° out of register, measured through said loading position, when said tubular portion and said body portion are in said operating position.
13. In an inhaler for powdered medicaments contained in a capsule, the improvement comprising a means for charging said inhaler with said capsule while maintaining said inhaler in connected relationship, comprising: A. an elongated mouth-piece, comprising on one end an air outlet and on the other end a pivotal securing means, an eccentrically mounted pivot pin, a latch, an air-pervious capsule-retaining means, and an air passage connecting said air outlet and said air-pervious capsule-retaining means; and B. a base, comprising an eccentrically mounted pivot-pin receiving means, a latch keeper, an air inlet, a capsule chamber of a size to loosely hold said capsule, and a radially extending piercing means for said capsule, whereby operation of said inhaler enables said capsule to be charged into said capsule chamber when said mouth-piece and said base are pivotably separated and enables air to be drawn through said air inlet into said capsule chamber and through said air passage to said air outlet when said mouth-piece and said base are pivotably aligned.
14. The improvement in the inhaler of claim 13, where-in said base has an elliptical shape and wherein said elongated mouth-piece is covered and enclosed by a cap, having said elliptical shape, which contacts both said air outlet and said base when said mouth-piece and said base are pivotably aligned.
15. The improvement in the inhaler of claim 13 wherein said cap has a pair of wing flaps which contact said radially extending piercing means when said mouth-piece and said base are pivotably aligned.
16. The improvement in the inhaler of claim 13 wherein said radially extending piercing means is spring biased.
17. The improvement in the inhaler of claim 13,wherein said capsule chamber comprises an elongated capsule recess, within which said capsule fits loosely and into which said capsule is charged, and a cylindrically shaped spinning chamber which is operably connected to said elongated capsule recess and to said air-pervious capsule-retaining means when said mouth-piece and said base are pivotably aligned.
18. The improvement in the inhaler of claim 17 wherein said air inlet is tangentially disposed in relation to said capsule chamber, whereby said operation of said inhaler produces a rush of air through said air inlet into said capsule chamber to create a vortex therein which lifts said capsule from said capsule recess into said cylindrical spinning chamber and spins it therewithin.
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| IT86249/74A IT1016489B (en) | 1974-03-18 | 1974-03-18 | INHALER |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| CA1046882A true CA1046882A (en) | 1979-01-23 |
Family
ID=11330408
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| CA211,781A Expired CA1046882A (en) | 1974-03-18 | 1974-10-18 | Inhaler |
Country Status (31)
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| US (1) | US3991761A (en) |
| JP (1) | JPS5346400B2 (en) |
| AR (1) | AR202427A1 (en) |
| AT (1) | AT347016B (en) |
| BE (1) | BE821152A (en) |
| BG (1) | BG27054A3 (en) |
| BR (1) | BR7408621A (en) |
| CA (1) | CA1046882A (en) |
| CH (1) | CH572750A5 (en) |
| CS (1) | CS187429B2 (en) |
| DE (2) | DE2449179C3 (en) |
| DK (1) | DK152175C (en) |
| ES (1) | ES431010A1 (en) |
| FI (1) | FI56489C (en) |
| FR (1) | FR2264563B1 (en) |
| GB (1) | GB1485163A (en) |
| HU (1) | HU174930B (en) |
| IE (1) | IE40185B1 (en) |
| IL (1) | IL45846A (en) |
| IN (1) | IN142400B (en) |
| IT (1) | IT1016489B (en) |
| LU (1) | LU71109A1 (en) |
| NL (1) | NL176837C (en) |
| NO (1) | NO135303C (en) |
| PH (1) | PH15499A (en) |
| PL (1) | PL99318B1 (en) |
| SE (1) | SE411517B (en) |
| SU (1) | SU695529A3 (en) |
| TR (1) | TR18840A (en) |
| YU (1) | YU36612B (en) |
| ZA (1) | ZA746599B (en) |
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| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US2517482A (en) * | 1949-04-09 | 1950-08-01 | Sharp & Dohme Inc | Inhaler |
| US3669113A (en) * | 1966-03-07 | 1972-06-13 | Fisons Ltd | Inhalation device |
| GB1268051A (en) * | 1968-06-07 | 1972-03-22 | Fisons Pharmaceuticals Ltd | Inhalation device |
| IT941426B (en) * | 1971-07-17 | 1973-03-01 | Isf Spa | SWIRL-CHAMBER INHALER FOR POWDER-SHAPING MEDICINAL SUBSTANCES |
-
1974
- 1974-03-18 IT IT86249/74A patent/IT1016489B/en active
- 1974-10-14 IN IN2283/CAL/74A patent/IN142400B/en unknown
- 1974-10-14 HU HU74IE655A patent/HU174930B/en unknown
- 1974-10-14 AT AT824574A patent/AT347016B/en not_active IP Right Cessation
- 1974-10-14 TR TR18840A patent/TR18840A/en unknown
- 1974-10-14 CS CS747016A patent/CS187429B2/en unknown
- 1974-10-14 IL IL45846A patent/IL45846A/en unknown
- 1974-10-15 FR FR7434565A patent/FR2264563B1/fr not_active Expired
- 1974-10-15 PH PH16419A patent/PH15499A/en unknown
- 1974-10-15 ES ES431010A patent/ES431010A1/en not_active Expired
- 1974-10-15 IE IE2125/74A patent/IE40185B1/en unknown
- 1974-10-15 LU LU71109A patent/LU71109A1/xx unknown
- 1974-10-15 FI FI3001/74A patent/FI56489C/en active
- 1974-10-15 SE SE7412974A patent/SE411517B/en not_active IP Right Cessation
- 1974-10-16 AR AR256134A patent/AR202427A1/en active
- 1974-10-16 DE DE2449179A patent/DE2449179C3/en not_active Expired
- 1974-10-16 BE BE149605A patent/BE821152A/en not_active IP Right Cessation
- 1974-10-16 BR BR8621/74A patent/BR7408621A/en unknown
- 1974-10-16 DE DE7434592U patent/DE7434592U/en not_active Expired
- 1974-10-16 NL NLAANVRAGE7413625,A patent/NL176837C/en not_active IP Right Cessation
- 1974-10-16 ZA ZA00746599A patent/ZA746599B/en unknown
- 1974-10-17 SU SU742074688A patent/SU695529A3/en active
- 1974-10-17 GB GB44994/74A patent/GB1485163A/en not_active Expired
- 1974-10-17 JP JP11875074A patent/JPS5346400B2/ja not_active Expired
- 1974-10-17 DK DK544174A patent/DK152175C/en active
- 1974-10-17 NO NO743761A patent/NO135303C/no unknown
- 1974-10-18 CH CH1400074A patent/CH572750A5/xx not_active IP Right Cessation
- 1974-10-18 CA CA211,781A patent/CA1046882A/en not_active Expired
- 1974-10-18 YU YU2791/74A patent/YU36612B/en unknown
- 1974-10-21 US US05/516,829 patent/US3991761A/en not_active Expired - Lifetime
- 1974-10-27 BG BG7427972A patent/BG27054A3/xx not_active Expired
- 1974-11-09 PL PL1974175457A patent/PL99318B1/en unknown
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