CA1209645A - Endotract antenna device for hyperthermia - Google Patents

Endotract antenna device for hyperthermia

Info

Publication number
CA1209645A
CA1209645A CA000437376A CA437376A CA1209645A CA 1209645 A CA1209645 A CA 1209645A CA 000437376 A CA000437376 A CA 000437376A CA 437376 A CA437376 A CA 437376A CA 1209645 A CA1209645 A CA 1209645A
Authority
CA
Canada
Prior art keywords
antenna device
balloon
antenna
tube
draining
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired
Application number
CA000437376A
Other languages
French (fr)
Inventor
Akira Sogawa
Tetsuya Hotta
Hidenobu Kai
Yoshio Kawai
Kiyoshi Inokuchi
Keizo Sugimachi
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Kureha Corp
Original Assignee
Kureha Corp
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Kureha Corp filed Critical Kureha Corp
Application granted granted Critical
Publication of CA1209645A publication Critical patent/CA1209645A/en
Expired legal-status Critical Current

Links

Classifications

    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61BDIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B18/00Surgical instruments, devices or methods for transferring non-mechanical forms of energy to or from the body
    • A61B18/18Surgical instruments, devices or methods for transferring non-mechanical forms of energy to or from the body by applying electromagnetic radiation, e.g. microwaves
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61BDIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B18/00Surgical instruments, devices or methods for transferring non-mechanical forms of energy to or from the body
    • A61B18/18Surgical instruments, devices or methods for transferring non-mechanical forms of energy to or from the body by applying electromagnetic radiation, e.g. microwaves
    • A61B18/1815Surgical instruments, devices or methods for transferring non-mechanical forms of energy to or from the body by applying electromagnetic radiation, e.g. microwaves using microwaves
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61BDIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B18/00Surgical instruments, devices or methods for transferring non-mechanical forms of energy to or from the body
    • A61B2018/00005Cooling or heating of the probe or tissue immediately surrounding the probe
    • A61B2018/00011Cooling or heating of the probe or tissue immediately surrounding the probe with fluids
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61BDIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B18/00Surgical instruments, devices or methods for transferring non-mechanical forms of energy to or from the body
    • A61B2018/00315Surgical instruments, devices or methods for transferring non-mechanical forms of energy to or from the body for treatment of particular body parts
    • A61B2018/00553Sphincter

Abstract

TITLE OF THE INVENTION

Endotract Antenna Device For Hyperthermia ABSTRACT OF THE DISCLOSURE

The endotract antenna for hyperthermia comprising a microwave radiation antenna, a balloon-like member made of a thin polymeric film and surrounding the antenna and means for feeding and draining a cooling liquid to and from the inside of the balloon-like member, enables effective warming of the endotract lesion such as tumor by effectively applying the energy of the microwaves emitted from the antenna to the endotract lesion.

Description

~ll2~

This invention concerns an endotract antenna device for hyperthermia and, more specifically, lt relates to an endotract antenna device applied to the hyperthermia therapy of tumors or the likes on the organs inside the body.
In the hyperthermia therapy for carcinoma, which utilizes the property of the cancer cells that they are less resistant than normal cells against heat or elevated temperature, a microwave radiation antenna is used to warm the lesion for the therapy.
Ir is desired that the radiation antenna is as thin as possible so that it may be inserted deeply in-to the endotract o the body or the therapy of organs inside the body, or example, a digestive organ,and a sort of linear dipole antenna has been employed so far for such a purpose.
However, it is difficult to dispose the conventional linear dipole antenna in direct contact with a surface of the organ at the lesion, and there is fear that gases or the fluid may remain in the gap between the antenna and the~ surface of the organ.
` As a result, the electromagnetic energy emitted from the microwave antenna of such endotract antenna device is absorbed by the body fluid in the gap, or reflected at the yap and can not always serve for effective and uniform warming of the lesion.
This invention has been made in view of the foregoings and it is an object of this invention to provide an endotract antenna device capable of effectively warming the lesion at ~k~

~L209~;45 the wall of the tract or lumen.
The above-mentioned object can be attained according to' this invention by an endotract antenna device ~or hyperthermia comprising an antenna for radiating microwave, a balloon-like member made of a thin polymeric fllm and surrounding the antenna, and means for feeding and draining cooling liquid to and from the balloon-like member.
This invention is to be described in~ more details referring to the accompanying drawing, by which the foregoing and o-ther objects, as well as the features of this invention will be made clearer, in which Fig. 1 shows an e~plana-tory view Eor an endotract an-tenna device for hyperthermia as a preferred embodiment of this invention, with a balloon being in a slightly expanded state. ~
Referrlng to Fig. l, an endotract antenna devlce for hyperthermia~l comprises~a coaxlal cable 6 for the microwave transmission connected at one end 2 to a microwave oscillator or generator 3 whlch can continuously~ generates microwaves, for example, at a frequency of 91S MHz and formed at -the other end 4 with a sort of linear dipole~antenna 5, a balloon 8 made of a flexible and elastlc polymerlc thin film and forming a chamber 7 of a variable volume~which su~rrounds the~microwave~radlatlon ~ ~ ;
antenna S and reoeives purified water for cooling,~a feed tube~ll opened at one end 9 thereof to the water-containing chamber 7 ahd communicated at the other end 9a~thereof with a feed pump 10 so as to feed the purified water into the chamber 7, andla draining tube : : :

~2a~45 15 connected at one end 12 thereof to the balloon 8 and opened at the other end 13 thereoi by way of a throttling device 14 for the water pressure control so as to drain the water from the balloon 8~ In Fig. 1, the pu~p 10, the feed tube ll, the throttling device 14 and the draining tube 15 constitute means for feeding and draining the cooling water.
The frequency o~ the microwaves generated fro~ the oscillator 3 to be applied to tumors at the wall of the tract i9 usually in the order of between 300 - 3000 MHz. The frequency of the microwaves may be selected from a plurality of oscillation ~requencies that can be generated from the oscillator 3 dependin~
on the size of the antenna 5. The ou-tput power oE the oscillator may b~ in the order of 10 to 200 watt for example.
Referring to the coaxlal;cable 6 which is extended through the drainlng~tube 15 lt lS preferably~designed, for enabling effective transmission o~ the microwaves and easy insertlon of the tube 15 into the tract where the lesian is located, such that the cable has an outer diameter of about
2 - 10 mm and comprises a central or inner conductor ln the form of a single wire or twisted wires made of silver-plated copper wire, an insulatorlmade of a polymeric material wit~ less ;
dielectric loss~whlch is dLsposed 'oetween the central conduatar ;
and an outer canduatar~,~the auter shLeldlng aanductar ln the l form of a braided tube ar helically wound bralded aable made ~ ~ ~¦
of silver-plated annealed capper wlres and the protection coatLng~
ar jacket at the outer perip-ery of the outer con~uator maue af ~L20~6~S

a polymeric material such as fluoro resin, polyvinyl chloride, polyethylene and silicone resin which exhibits no to~icity ln the tract.
The microwave radiation antenna 5 comprises a tubular conductor 16 of about A/4 in length (A is~
a wavelength of the microwave in the chamber 7~ which is electrically connected to -the central conductor and another t-ubular conductor 17 also of about A/4 in length which is electrically connected to the outer conductor and spaced apart from the tubular conduc-tor 16 a-t a short insulating portion 18.

The tubular conductors 16 and 17 are preferably of an identical shape or configuration. Instead of providing the tubular conductor 16, the top end of the central conductor may be exposed at least by the length of about A/4.
The baIloon 8 is secured at its base portion to the end 12 of t~e water-draLn tube lS and secured about at the center of its top end 1~9 to the top end of the microwave antenna 5.
Xt is preferred that the polymeric film of the balloon 8 is made of highly flexible material so that the film can be in close contact~with the surface of the wall of the tract where the lesion i5 located and that the film is made as thin as possible so that it may absorb less~energy of the microwaves emitted or transmitted from the an-tenna S, provided that the film has an elasticity sufficient to contain water therein under a certain 1ZI~9645 pressure. In the case of using a thin rubber film for the balloon 8, the film thickness is, for instance, less than 0.5 mm (energy loss of about 30 ~) and, preferably, less than 0.1 mm (energy loss of about 10 - 15 ~). Although the balloon 8 in the illustrated embodiment is shaped such that it is expandable through an oval or elliptic shape to a generally spheric shape, it may take any other configuration. For instance, the balloon 8 may be protruded longitudinally at the top end 19 and, in this case, the top end of the antenna 5 may he inserted into but not fix~d to the elongated recess of the top end 19. The film mat~ri~l Eor the balloon 8 is preferably rubbery polymeric mater.lal, Eor example, natural rubber or syn-thetic rubber such as silicone rubber. ~
In order to transmit the microwaves emitted fron the antenna S as eeectively as possible to the lesion, the coollng medium ~lowin~ the inside of the bal;loon 8, preferably, comprises liquid medlum at least mainly composed of water so that the emitted microwaves are transmitted therein substantially at the same wa~elength as in the lesion. Purlfied water wlth less transmission loss such as absorption is more preferred.
¦ The purlfied water as the coollng llquid~flowing lnside~
: :
of the balloon 8 is kept at an appropriate temperature of about~
O - 45C and,~`preferably, about lS - 42C so that the temperature at the lesion can be maintalned at 4Z - 45C by the purified~water in co-operation with the~antenna S. ~
Further, the flow rate of the cooling~water i9 ~:
: : ::

lZ09645 controlled by the throttling device 14. The throttling device 14 comprises a manually- or automatically-controlled valve, the opening degree of which can be adjusted continuously. The throttling device or valve 14 also serves to produce an adequate pressure within the balloon 8 so as to expand the balloon 8 into an intimate contact wlth the wall of the tràct or lumen organ.
In the illustrated embodiment, the drain tube 15 is constituted as a device main body which is to be inserted through the tract or lumen and through~which the coaxial cable 6 and the feed tube 11 are extended. Alternatively, the feed tube 11 may be modified to be constituted as the device main body while extending the drain tube 15 and the coaxial cable 6 inside of the Eeed tube 11. In -this modified embodlment, the ~ase portion o the balloon 8 is secured to the end of the water-eed tube 11. Furthermore, the feed~tube 11, the drain tube 15 and the coaxial cable 6 may be bundled in close contact together at their respective outer~circumferential surfaces so that the three members form an elongated antenna device main body as a whole, with the balloon 8 belng capped over the open ends of the tubes 11, 15 so as to surround the antenna 5, in the case where the assembly can be formed so smooth and thin as can be intaken, for examplet from the mouth Lnto the stomach ~ ~
The puriied water may be used recyclically by ~ ;
connecting the drain tube 15 to the pump 10 by way of a reservolr not shown. Reference numera~l 20 in the drawing denotes sealed~
portions to prevent the leak of the water.

: ~
:

~2~g64S

A thermosens~r or temperature detector 21 is fixed to the outer surface of the central por-tion of the circumferential wall of the balloon 8 to detect the temperature at the film or membrane surface of the balloon 8, that is, the temperature at the inner surface of the wall of the tract organ. The thermosensor 21 may be a thermocouple or thermistor. The lead 22 for the thermosensor 21 is disposed along the outer surf~ce of the drain tube 15 constituting the device main body in~the illustrated embodiment, it may, however, be passed through the inside of the drain tube 15 as the device main body if desired. The average output ~rom the oscillator 3 and the temperature o~ the coollng wat~r ~ecl to the balloon 8 are controlled dependin~ on the outp~t signal from the thermosensor 21, that is, on the temperature detected by the sensor 21 so that -the temperature of the lesion may be kept a-t about 42 - 45C. The temperature control may be carried out automatically by a suitable control means.
In the endotract antenna device for hyperthermia l constituted as described above, since the microwave radiation antenna 5 is disposed to the inside of the balloon 8 through which the cooling liquid passes, the balloon 8 can be deformed just correspondlng to the uneven inner profile of the wall of the tract organ and put to an lntlmate fittlng~with the inner surface of the wall, that is, the surface~of the lesion by the control of the flow rate and/or the pressure of the cooling liquid flowi~ng inside of the balloon 8~ whereby~the microwave emitted from the antenna 5 can be transmitted with little transmlssion loss to the .

lZ09~i45 lesion through the purified water in the chamber 7 and the thin film of the balloon 8. Furthermore, control for the -temperature and the flow rate of the cooling water 10wing inside of the balloon 8 can ensure the hypothermia therapy while preventing or avoiding localized over-heating and maintaining the temperature of the wide lesion area at a temperature of between 42 - 45C.
As described above, according to this invention, since the endotract antenna device for hyperthermia comprise~
a microwave radiation antenna, a balloon-like member made of a polymeric thin film and surrounding the antenna, and means for .Eeeding and draining a cooling liquid to and from the inside Qf the balloon-member, the energy o~ the microwa~es emitted Erom I.
th~ antenna can be efEectively given to the lesion in the tract or lumen organ, thereby enabling to warm tle lesion effectively.

~ ~ I

~ ~:

Claims (20)

WHAT IS CLAIMED IS:
1. An endotract antenna device for hyperthermia comprising an antenna for radiating microwave, a balloon-like member made of a polymeric thin film and surrounding said antenna, and means for feeding and draining a cooling liquid to and from an inside of said balloon-like member.
2. The antenna device as defined in claim 1, in which said radiation antenna comprises a generally linear dipole antenna.
3. The antenna device as defined in claim 2, in which the dipole antenna comprises a pair of conductors each having a same configuration.
4. The antenna device as defined in claim 2, in which the dipole antenna comprises a pair of conductors, one of the paired conductors being a central conductor of a coaxial cable.
5. The antenna device as defined in claim 1, in which said radiation antenna is connected by way of a coaxial cable to a microwave oscillator.
6. The antenna device as defined in claim 1, in which said radiation antenna is fixed at a top end thereof with a central portion of a top end of said balloon-like member.
7. The antenna device as defined in claim 1, in which the thin polymeric film of said balloon-like member is flexible and elastic.
8. The antenna device as defined in claim 1, in which the thin polymeric film is made of rubber.
9. The antenna device as defined in claim 8, in which the rubber is synthetic rubber.
10. The antenna device as defined in claim 8, in which the rubber is natural rubber.
11. The antenna device as defined in claim 1, in which said feeding and draining means comprises a feeding tube communicated at one end thereof with said balloon-like member so as to feed the cooling liquid to the inside of said balloon-like member and a draining tube communicated at one end thereof with said balloon-like member so as to drain the cooling liquid from said balloon-like member.
12. The antenna device as defined in claim 11, in which said feeding and draining means further comprises a pump connected to an other end of the feeding tube so as to supply the cooling liquid by way of the feeding tube to the inside of said balloon-like member.
13. The antenna device as defined in claim 12, in which said feeding and draining means further comprises a throttling means for controlling a flow rate or a pressure of the cooling liquid flowing the inside of said balloon-like member.
14. The antenna device as defined in claim 13, in which the throttling means is disposed at an other end of the draining tube.
15. The antenna device as defined in claim 14, in which said balloon-like member is capped liquid-tightly over the one end of the draining tube, the feeding tube is inserted in the draining tube at a side of the one end of the draining tube, and a transmission line for connecting a microwave oscillator with said radiation antenna is inserted in the draining tube.
16. The antenna device as defined in claim 14, in which said balloon-like member is capped liquid-tightly over the one end of the. feeding tube, the draining tube is inserted in the feeding tube at a side of the one end of the feeding tube, and a transmission line for connecting a microwave oscillator with said radiation antenna is inserted in the feeding tube.
17. The antenna device as defined in claim 11, in which said feeding and draining means comprises means for controlling a temperature of the cooling liquid to be supplied by way of the feeding tube to said balloon-like member.
18. The antenna device as defined in claim 1, in which the cooling liquid is water.
19. The antenna device as defined in claim 18, in which the water is purified water.
20. The antenna device as defined in claim 1, in which a thermosensor is disposed on a surface of said balloon-like member.
CA000437376A 1982-09-27 1983-09-22 Endotract antenna device for hyperthermia Expired CA1209645A (en)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
JP57167978A JPS5957650A (en) 1982-09-27 1982-09-27 Probe for heating body cavity
JP167978/82 1982-09-27

Publications (1)

Publication Number Publication Date
CA1209645A true CA1209645A (en) 1986-08-12

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Family Applications (1)

Application Number Title Priority Date Filing Date
CA000437376A Expired CA1209645A (en) 1982-09-27 1983-09-22 Endotract antenna device for hyperthermia

Country Status (3)

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US (1) US4662383A (en)
JP (1) JPS5957650A (en)
CA (1) CA1209645A (en)

Families Citing this family (203)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JPS6055966A (en) * 1983-09-05 1985-04-01 オリンパス光学工業株式会社 Medical electrode apparatus
US4800899A (en) * 1984-10-22 1989-01-31 Microthermia Technology, Inc. Apparatus for destroying cells in tumors and the like
US5019075A (en) * 1984-10-24 1991-05-28 The Beth Israel Hospital Method and apparatus for angioplasty
US5226430A (en) * 1984-10-24 1993-07-13 The Beth Israel Hospital Method for angioplasty
US4700716A (en) * 1986-02-27 1987-10-20 Kasevich Associates, Inc. Collinear antenna array applicator
JPS6323676A (en) * 1986-07-17 1988-01-30 オリンパス光学工業株式会社 High frequency heating method and apparatus
JPH0511882Y2 (en) * 1987-01-06 1993-03-25
US4819655A (en) * 1987-08-04 1989-04-11 Webler William E Injectateless thermal cardiac output determination method and apparatus
US5097845A (en) * 1987-10-15 1992-03-24 Labthermics Technologies Microwave hyperthermia probe
DE3743578A1 (en) * 1987-12-22 1989-07-13 Andreas Dr Zeiher BALLOON CATHETER FOR RECANALIZING STENOSES IN BODY CHANNELS, IN PARTICULAR CORONARY VESSELS AND PERIPHERAL ARTERIAL VESSELS
US5344435A (en) * 1988-07-28 1994-09-06 Bsd Medical Corporation Urethral inserted applicator prostate hyperthermia
US4955377A (en) * 1988-10-28 1990-09-11 Lennox Charles D Device and method for heating tissue in a patient's body
US5191883A (en) * 1988-10-28 1993-03-09 Prutech Research And Development Partnership Ii Device for heating tissue in a patient's body
US5150717A (en) * 1988-11-10 1992-09-29 Arye Rosen Microwave aided balloon angioplasty with guide filament
FR2639238B1 (en) * 1988-11-21 1991-02-22 Technomed Int Sa APPARATUS FOR SURGICAL TREATMENT OF TISSUES BY HYPERTHERMIA, PREFERABLY THE PROSTATE, COMPRISING MEANS OF THERMAL PROTECTION COMPRISING PREFERABLY RADIOREFLECTIVE SCREEN MEANS
FR2693116B1 (en) * 1992-07-06 1995-04-28 Technomed Int Sa Urethral probe and apparatus for the therapeutic treatment of prostate tissue by thermotherapy.
US4979948A (en) * 1989-04-13 1990-12-25 Purdue Research Foundation Method and apparatus for thermally destroying a layer of an organ
US5007437A (en) * 1989-06-16 1991-04-16 Mmtc, Inc. Catheters for treating prostate disease
JP2984056B2 (en) * 1989-09-08 1999-11-29 ボストン サイエンティフィック コーポレイション Physiological low pressure angioplasty
US5103804A (en) * 1990-07-03 1992-04-14 Boston Scientific Corporation Expandable tip hemostatic probes and the like
US5417686A (en) * 1990-07-10 1995-05-23 The Texas A&M University System Temperature control mechanisms for a micro heat pipe catheter
US5190539A (en) * 1990-07-10 1993-03-02 Texas A & M University System Micro-heat-pipe catheter
JPH05506174A (en) * 1990-09-14 1993-09-16 アメリカン・メディカル・システムズ・インコーポレーテッド Combined hyperthermia and dilatation catheter
AU9027191A (en) 1990-11-05 1992-05-26 Bsd Medical Corporation Urethral inserted applicator for prostate hyperthermia
US5301687A (en) * 1991-06-06 1994-04-12 Trustees Of Dartmouth College Microwave applicator for transurethral hyperthermia
IT1251997B (en) 1991-11-11 1995-05-27 San Romanello Centro Fond RADIANT DEVICE FOR HYPERTHERMIA
US5330518A (en) * 1992-03-06 1994-07-19 Urologix, Inc. Method for treating interstitial tissue associated with microwave thermal therapy
US5413588A (en) * 1992-03-06 1995-05-09 Urologix, Inc. Device and method for asymmetrical thermal therapy with helical dipole microwave antenna
FR2689768B1 (en) * 1992-04-08 1997-06-27 Inst Nat Sante Rech Med APPLICATOR DEVICE FOR MICROWAVE HYPERTHERMIA IN A CERTAIN BODY.
US5443470A (en) * 1992-05-01 1995-08-22 Vesta Medical, Inc. Method and apparatus for endometrial ablation
US5562720A (en) * 1992-05-01 1996-10-08 Vesta Medical, Inc. Bipolar/monopolar endometrial ablation device and method
US5277201A (en) * 1992-05-01 1994-01-11 Vesta Medical, Inc. Endometrial ablation apparatus and method
US6086581A (en) 1992-09-29 2000-07-11 Ep Technologies, Inc. Large surface cardiac ablation catheter that assumes a low profile during introduction into the heart
US6537306B1 (en) * 1992-11-13 2003-03-25 The Regents Of The University Of California Method of manufacture of a transurethral ultrasound applicator for prostate gland thermal therapy
EP0597463A3 (en) * 1992-11-13 1996-11-06 Dornier Med Systems Inc Thermotherapiesonde.
US5733315A (en) * 1992-11-13 1998-03-31 Burdette; Everette C. Method of manufacture of a transurethral ultrasound applicator for prostate gland thermal therapy
US5837003A (en) * 1993-02-10 1998-11-17 Radiant Medical, Inc. Method and apparatus for controlling a patient's body temperature by in situ blood temperature modification
US6033383A (en) * 1996-12-19 2000-03-07 Ginsburg; Robert Temperature regulating catheter and methods
US6110168A (en) * 1993-02-10 2000-08-29 Radiant Medical, Inc. Method and apparatus for controlling a patient's body temperature by in situ blood temperature modifications
US6849083B2 (en) * 1993-02-10 2005-02-01 Radiant Medical, Inc. Method and apparatus for controlling a patients's body temperature by in situ blood temperature modification
US6620188B1 (en) 1998-08-24 2003-09-16 Radiant Medical, Inc. Methods and apparatus for regional and whole body temperature modification
US5549639A (en) * 1994-09-16 1996-08-27 Sandia Corporation Non-invasive hyperthermia apparatus including coaxial applicator having a non-invasive radiometric receiving antenna incorporated therein and method of use thereof
EP1011495B1 (en) 1995-05-04 2005-11-09 Sherwood Services AG Cool-tip electrode thermosurgery system
US6575969B1 (en) 1995-05-04 2003-06-10 Sherwood Services Ag Cool-tip radiofrequency thermosurgery electrode system for tumor ablation
US5683382A (en) * 1995-05-15 1997-11-04 Arrow International Investment Corp. Microwave antenna catheter
US5628770A (en) * 1995-06-06 1997-05-13 Urologix, Inc. Devices for transurethral thermal therapy
US5645528A (en) * 1995-06-06 1997-07-08 Urologix, Inc. Unitary tip and balloon for transurethral catheter
US5843144A (en) * 1995-06-26 1998-12-01 Urologix, Inc. Method for treating benign prostatic hyperplasia with thermal therapy
US6475213B1 (en) 1996-01-19 2002-11-05 Ep Technologies, Inc. Method of ablating body tissue
US5938692A (en) * 1996-03-26 1999-08-17 Urologix, Inc. Voltage controlled variable tuning antenna
US7604633B2 (en) 1996-04-12 2009-10-20 Cytyc Corporation Moisture transport system for contact electrocoagulation
US6813520B2 (en) 1996-04-12 2004-11-02 Novacept Method for ablating and/or coagulating tissue using moisture transport
US5769880A (en) * 1996-04-12 1998-06-23 Novacept Moisture transport system for contact electrocoagulation
US5776129A (en) * 1996-06-12 1998-07-07 Ethicon Endo-Surgery, Inc. Endometrial ablation apparatus and method
US5800486A (en) * 1996-06-17 1998-09-01 Urologix, Inc. Device for transurethral thermal therapy with cooling balloon
US5861021A (en) * 1996-06-17 1999-01-19 Urologix Inc Microwave thermal therapy of cardiac tissue
US5792070A (en) * 1996-08-30 1998-08-11 Urologix, Inc. Rectal thermosensing unit
US6073052A (en) * 1996-11-15 2000-06-06 Zelickson; Brian D. Device and method for treatment of gastroesophageal reflux disease
US5829519A (en) * 1997-03-10 1998-11-03 Enhanced Energy, Inc. Subterranean antenna cooling system
US6223085B1 (en) 1997-05-06 2001-04-24 Urologix, Inc. Device and method for preventing restenosis
US6312426B1 (en) * 1997-05-30 2001-11-06 Sherwood Services Ag Method and system for performing plate type radiofrequency ablation
US6419643B1 (en) 1998-04-21 2002-07-16 Alsius Corporation Central venous catheter with heat exchange properties
US6368304B1 (en) 1999-02-19 2002-04-09 Alsius Corporation Central venous catheter with heat exchange membrane
US6338727B1 (en) 1998-08-13 2002-01-15 Alsius Corporation Indwelling heat exchange catheter and method of using same
US6126684A (en) 1998-04-21 2000-10-03 The Regents Of The University Of California Indwelling heat exchange catheter and method of using same
US6716236B1 (en) 1998-04-21 2004-04-06 Alsius Corporation Intravascular catheter with heat exchange element having inner inflation element and methods of use
US8551082B2 (en) 1998-05-08 2013-10-08 Cytyc Surgical Products Radio-frequency generator for powering an ablation device
US6216703B1 (en) 1998-05-08 2001-04-17 Thermatrx, Inc. Therapeutic prostatic thermotherapy
US6740082B2 (en) * 1998-12-29 2004-05-25 John H. Shadduck Surgical instruments for treating gastro-esophageal reflux
US6620189B1 (en) * 2000-02-28 2003-09-16 Radiant Medical, Inc. Method and system for control of a patient's body temperature by way of a transluminally insertable heat exchange catheter
US6673098B1 (en) * 1998-08-24 2004-01-06 Radiant Medical, Inc. Disposable cassette for intravascular heat exchange catheter
CA2340749A1 (en) * 1998-09-11 2000-03-23 Medivance Inc. Method and apparatus for providing localized heating of the preoptic anterior hypothalamus
WO2000023147A1 (en) 1998-10-20 2000-04-27 Dornier Medtech Holding International Gmbh Thermal therapy with tissue protection
US7364577B2 (en) 2002-02-11 2008-04-29 Sherwood Services Ag Vessel sealing system
US7901400B2 (en) 1998-10-23 2011-03-08 Covidien Ag Method and system for controlling output of RF medical generator
US7137980B2 (en) 1998-10-23 2006-11-21 Sherwood Services Ag Method and system for controlling output of RF medical generator
US6122551A (en) * 1998-12-11 2000-09-19 Urologix, Inc. Method of controlling thermal therapy
US6582398B1 (en) 1999-02-19 2003-06-24 Alsius Corporation Method of managing patient temperature with a heat exchange catheter
GB9904373D0 (en) * 1999-02-25 1999-04-21 Microsulis Plc Radiation applicator
US6161049A (en) 1999-03-26 2000-12-12 Urologix, Inc. Thermal therapy catheter
US6348039B1 (en) 1999-04-09 2002-02-19 Urologix, Inc. Rectal temperature sensing probe
US6272384B1 (en) 1999-05-27 2001-08-07 Urologix, Inc. Microwave therapy apparatus
US6478793B1 (en) 1999-06-11 2002-11-12 Sherwood Services Ag Ablation treatment of bone metastases
US20040215235A1 (en) 1999-11-16 2004-10-28 Barrx, Inc. Methods and systems for determining physiologic characteristics for treatment of the esophagus
US20060095032A1 (en) 1999-11-16 2006-05-04 Jerome Jackson Methods and systems for determining physiologic characteristics for treatment of the esophagus
WO2001035846A1 (en) 1999-11-16 2001-05-25 Ganz Robert A System and method of treating abnormal tissue in the human esophagus
US6640138B1 (en) 2000-08-04 2003-10-28 Thermatrx, Inc. Apparatus and method for heat treatment of tissue
US6866624B2 (en) 2000-12-08 2005-03-15 Medtronic Ave,Inc. Apparatus and method for treatment of malignant tumors
US20020178454A1 (en) * 2001-02-14 2002-11-28 Antoine Mark J. Broadcast television and satellite signal switching system and method for telephony signal insertion
US6641602B2 (en) 2001-04-13 2003-11-04 Alsius Corporation Method and device including a colo-rectal heat exchanger
WO2003000314A2 (en) * 2001-06-20 2003-01-03 The Regents Of The University Of California Hemodialysis system and method
WO2003024309A2 (en) * 2001-09-19 2003-03-27 Urologix, Inc. Microwave ablation device
US6752767B2 (en) 2002-04-16 2004-06-22 Vivant Medical, Inc. Localization element with energized tip
ATE371413T1 (en) 2002-05-06 2007-09-15 Covidien Ag BLOOD DETECTOR FOR CHECKING AN ELECTROSURGICAL UNIT
US8361067B2 (en) 2002-09-30 2013-01-29 Relievant Medsystems, Inc. Methods of therapeutically heating a vertebral body to treat back pain
US7258690B2 (en) 2003-03-28 2007-08-21 Relievant Medsystems, Inc. Windowed thermal ablation probe
US6907884B2 (en) 2002-09-30 2005-06-21 Depay Acromed, Inc. Method of straddling an intraosseous nerve
US7044948B2 (en) 2002-12-10 2006-05-16 Sherwood Services Ag Circuit for controlling arc energy from an electrosurgical generator
US7278984B2 (en) * 2002-12-31 2007-10-09 Alsius Corporation System and method for controlling rate of heat exchange with patient
US20040220557A1 (en) * 2003-04-30 2004-11-04 Eum Jay J. Closed system warming catheter and method of use
EP1617776B1 (en) 2003-05-01 2015-09-02 Covidien AG System for programing and controlling an electrosurgical generator system
US7311703B2 (en) * 2003-07-18 2007-12-25 Vivant Medical, Inc. Devices and methods for cooling microwave antennas
US7044960B2 (en) * 2003-09-17 2006-05-16 Medivance Incorporated Method and apparatus for providing non-invasive ultrasound heating of the preoptic anterior hypothalamus
EP1675499B1 (en) 2003-10-23 2011-10-19 Covidien AG Redundant temperature monitoring in electrosurgical systems for safety mitigation
WO2005050151A1 (en) 2003-10-23 2005-06-02 Sherwood Services Ag Thermocouple measurement circuit
US7396336B2 (en) 2003-10-30 2008-07-08 Sherwood Services Ag Switched resonant ultrasonic power amplifier system
US7131860B2 (en) 2003-11-20 2006-11-07 Sherwood Services Ag Connector systems for electrosurgical generator
JP4669218B2 (en) * 2003-12-26 2011-04-13 ニプロ株式会社 Medical equipment
US7150745B2 (en) 2004-01-09 2006-12-19 Barrx Medical, Inc. Devices and methods for treatment of luminal tissue
US7766905B2 (en) 2004-02-12 2010-08-03 Covidien Ag Method and system for continuity testing of medical electrodes
US7780662B2 (en) 2004-03-02 2010-08-24 Covidien Ag Vessel sealing system using capacitive RF dielectric heating
US20060276781A1 (en) * 2004-04-29 2006-12-07 Van Der Weide Daniel W Cannula cooling and positioning device
US7467015B2 (en) * 2004-04-29 2008-12-16 Neuwave Medical, Inc. Segmented catheter for tissue ablation
US20070055224A1 (en) * 2004-04-29 2007-03-08 Lee Fred T Jr Intralumenal microwave device
US7244254B2 (en) * 2004-04-29 2007-07-17 Micrablate Air-core microwave ablation antennas
US20050245920A1 (en) * 2004-04-30 2005-11-03 Vitullo Jeffrey M Cell necrosis apparatus with cooled microwave antenna
US8025638B2 (en) * 2004-05-21 2011-09-27 Keio University Balloon catheter, medical apparatus and method for treating living organ
US7553309B2 (en) * 2004-10-08 2009-06-30 Covidien Ag Electrosurgical system employing multiple electrodes and method thereof
US7776035B2 (en) * 2004-10-08 2010-08-17 Covidien Ag Cool-tip combined electrode introducer
US7282049B2 (en) * 2004-10-08 2007-10-16 Sherwood Services Ag Electrosurgical system employing multiple electrodes and method thereof
US7628786B2 (en) 2004-10-13 2009-12-08 Covidien Ag Universal foot switch contact port
US7731712B2 (en) 2004-12-20 2010-06-08 Cytyc Corporation Method and system for transcervical tubal occlusion
US7467075B2 (en) * 2004-12-23 2008-12-16 Covidien Ag Three-dimensional finite-element code for electrosurgery and thermal ablation simulations
US9474564B2 (en) 2005-03-31 2016-10-25 Covidien Ag Method and system for compensating for external impedance of an energy carrying component when controlling an electrosurgical generator
US7674260B2 (en) 2005-04-28 2010-03-09 Cytyc Corporation Emergency hemostasis device utilizing energy
WO2006127847A2 (en) * 2005-05-24 2006-11-30 Micrablate, Llc Microwave surgical device
WO2006138382A2 (en) * 2005-06-14 2006-12-28 Micrablate, Llc Microwave tissue resection tool
US7879031B2 (en) * 2005-09-27 2011-02-01 Covidien Ag Cooled RF ablation needle
US20070078454A1 (en) * 2005-09-30 2007-04-05 Mcpherson James W System and method for creating lesions using bipolar electrodes
US20070078453A1 (en) * 2005-10-04 2007-04-05 Johnson Kristin D System and method for performing cardiac ablation
US8734438B2 (en) 2005-10-21 2014-05-27 Covidien Ag Circuit and method for reducing stored energy in an electrosurgical generator
US7997278B2 (en) 2005-11-23 2011-08-16 Barrx Medical, Inc. Precision ablating method
US7959627B2 (en) * 2005-11-23 2011-06-14 Barrx Medical, Inc. Precision ablating device
US8702694B2 (en) 2005-11-23 2014-04-22 Covidien Lp Auto-aligning ablating device and method of use
US7947039B2 (en) 2005-12-12 2011-05-24 Covidien Ag Laparoscopic apparatus for performing electrosurgical procedures
US8685016B2 (en) 2006-01-24 2014-04-01 Covidien Ag System and method for tissue sealing
US9186200B2 (en) 2006-01-24 2015-11-17 Covidien Ag System and method for tissue sealing
US7513896B2 (en) 2006-01-24 2009-04-07 Covidien Ag Dual synchro-resonant electrosurgical apparatus with bi-directional magnetic coupling
US8216223B2 (en) 2006-01-24 2012-07-10 Covidien Ag System and method for tissue sealing
US8147485B2 (en) 2006-01-24 2012-04-03 Covidien Ag System and method for tissue sealing
US7972328B2 (en) 2006-01-24 2011-07-05 Covidien Ag System and method for tissue sealing
CA2574935A1 (en) 2006-01-24 2007-07-24 Sherwood Services Ag A method and system for controlling an output of a radio-frequency medical generator having an impedance based control algorithm
CA2574934C (en) 2006-01-24 2015-12-29 Sherwood Services Ag System and method for closed loop monitoring of monopolar electrosurgical apparatus
US7651493B2 (en) 2006-03-03 2010-01-26 Covidien Ag System and method for controlling electrosurgical snares
US7648499B2 (en) 2006-03-21 2010-01-19 Covidien Ag System and method for generating radio frequency energy
US10363092B2 (en) * 2006-03-24 2019-07-30 Neuwave Medical, Inc. Transmission line with heat transfer ability
US8672932B2 (en) * 2006-03-24 2014-03-18 Neuwave Medical, Inc. Center fed dipole for use with tissue ablation systems, devices and methods
US8795270B2 (en) * 2006-04-24 2014-08-05 Covidien Ag System and method for ablating tissue
US7651492B2 (en) 2006-04-24 2010-01-26 Covidien Ag Arc based adaptive control system for an electrosurgical unit
US20070258838A1 (en) * 2006-05-03 2007-11-08 Sherwood Services Ag Peristaltic cooling pump system
US20070260240A1 (en) 2006-05-05 2007-11-08 Sherwood Services Ag Soft tissue RF transection and resection device
US8753334B2 (en) 2006-05-10 2014-06-17 Covidien Ag System and method for reducing leakage current in an electrosurgical generator
US10376314B2 (en) 2006-07-14 2019-08-13 Neuwave Medical, Inc. Energy delivery systems and uses thereof
US11389235B2 (en) * 2006-07-14 2022-07-19 Neuwave Medical, Inc. Energy delivery systems and uses thereof
US7763018B2 (en) * 2006-07-28 2010-07-27 Covidien Ag Cool-tip thermocouple including two-piece hub
US7731717B2 (en) 2006-08-08 2010-06-08 Covidien Ag System and method for controlling RF output during tissue sealing
US8034049B2 (en) 2006-08-08 2011-10-11 Covidien Ag System and method for measuring initial tissue impedance
US20080071269A1 (en) * 2006-09-18 2008-03-20 Cytyc Corporation Curved Endoscopic Medical Device
US8486060B2 (en) * 2006-09-18 2013-07-16 Cytyc Corporation Power ramping during RF ablation
US7794457B2 (en) 2006-09-28 2010-09-14 Covidien Ag Transformer for RF voltage sensing
US7846160B2 (en) 2006-12-21 2010-12-07 Cytyc Corporation Method and apparatus for sterilization
US8211099B2 (en) 2007-01-31 2012-07-03 Tyco Healthcare Group Lp Thermal feedback systems and methods of using the same
WO2008137757A1 (en) 2007-05-04 2008-11-13 Barrx Medical, Inc. Method and apparatus for gastrointestinal tract ablation for treatment of obesity
US8777941B2 (en) 2007-05-10 2014-07-15 Covidien Lp Adjustable impedance electrosurgical electrodes
US9486269B2 (en) * 2007-06-22 2016-11-08 Covidien Lp Electrosurgical systems and cartridges for use therewith
US8784338B2 (en) * 2007-06-22 2014-07-22 Covidien Lp Electrical means to normalize ablational energy transmission to a luminal tissue surface of varying size
US8251992B2 (en) 2007-07-06 2012-08-28 Tyco Healthcare Group Lp Method and apparatus for gastrointestinal tract ablation to achieve loss of persistent and/or recurrent excess body weight following a weight-loss operation
KR101547931B1 (en) 2007-07-06 2015-08-28 코비디엔 엘피 Ablation in the gastrointestinal tract to achieve hemostasis and eradicate lesions with a propensity for bleeding
US7834484B2 (en) 2007-07-16 2010-11-16 Tyco Healthcare Group Lp Connection cable and method for activating a voltage-controlled generator
US8646460B2 (en) * 2007-07-30 2014-02-11 Covidien Lp Cleaning device and methods
US8273012B2 (en) * 2007-07-30 2012-09-25 Tyco Healthcare Group, Lp Cleaning device and methods
US8181995B2 (en) * 2007-09-07 2012-05-22 Tyco Healthcare Group Lp Cool tip junction
US8216220B2 (en) 2007-09-07 2012-07-10 Tyco Healthcare Group Lp System and method for transmission of combined data stream
US8512332B2 (en) 2007-09-21 2013-08-20 Covidien Lp Real-time arc control in electrosurgical generators
US8292880B2 (en) 2007-11-27 2012-10-23 Vivant Medical, Inc. Targeted cooling of deployable microwave antenna
US8945111B2 (en) 2008-01-23 2015-02-03 Covidien Lp Choked dielectric loaded tip dipole microwave antenna
US8226639B2 (en) 2008-06-10 2012-07-24 Tyco Healthcare Group Lp System and method for output control of electrosurgical generator
US8608739B2 (en) * 2008-07-22 2013-12-17 Covidien Lp Electrosurgical devices, systems and methods of using the same
US8251987B2 (en) 2008-08-28 2012-08-28 Vivant Medical, Inc. Microwave antenna
EP3406210A1 (en) 2008-09-26 2018-11-28 Relievant Medsystems, Inc. Systems and for navigating an instrument through bone
US10028753B2 (en) 2008-09-26 2018-07-24 Relievant Medsystems, Inc. Spine treatment kits
US8262652B2 (en) 2009-01-12 2012-09-11 Tyco Healthcare Group Lp Imaginary impedance process monitoring and intelligent shut-off
US20100256735A1 (en) * 2009-04-03 2010-10-07 Board Of Regents, The University Of Texas System Intraluminal stent with seam
DK2459096T3 (en) 2009-07-28 2015-01-19 Neuwave Medical Inc ablation device
US9113926B2 (en) * 2009-09-29 2015-08-25 Covidien Lp Management of voltage standing wave ratio at skin surface during microwave ablation
EP3804651A1 (en) 2010-05-03 2021-04-14 Neuwave Medical, Inc. Energy delivery systems
US8740893B2 (en) * 2010-06-30 2014-06-03 Covidien Lp Adjustable tuning of a dielectrically loaded loop antenna
US10278774B2 (en) 2011-03-18 2019-05-07 Covidien Lp Selectively expandable operative element support structure and methods of use
AU2012239878B2 (en) * 2011-04-08 2015-01-29 Covidien Lp Flexible microwave catheters for natural or artificial lumens
CN107224325B (en) 2011-12-21 2020-09-01 纽华沃医药公司 Energy delivery system and use thereof
AU2012362524B2 (en) 2011-12-30 2018-12-13 Relievant Medsystems, Inc. Systems and methods for treating back pain
US10588691B2 (en) 2012-09-12 2020-03-17 Relievant Medsystems, Inc. Radiofrequency ablation of tissue within a vertebral body
EP2914186B1 (en) 2012-11-05 2019-03-13 Relievant Medsystems, Inc. Systems for creating curved paths through bone and modulating nerves within the bone
US20140128858A1 (en) * 2012-11-08 2014-05-08 Covidien Lp Systems and methods for performing endometrial ablation
US9278023B2 (en) 2012-12-14 2016-03-08 Zoll Circulation, Inc. System and method for management of body temperature
US9872719B2 (en) 2013-07-24 2018-01-23 Covidien Lp Systems and methods for generating electrosurgical energy using a multistage power converter
US9636165B2 (en) 2013-07-29 2017-05-02 Covidien Lp Systems and methods for measuring tissue impedance through an electrosurgical cable
US9724151B2 (en) 2013-08-08 2017-08-08 Relievant Medsystems, Inc. Modulating nerves within bone using bone fasteners
WO2017075067A1 (en) 2015-10-26 2017-05-04 Neuwave Medical, Inc. Energy delivery systems and uses thereof
EP3808302B1 (en) 2016-04-15 2023-07-26 Neuwave Medical, Inc. System for energy delivery
US11672596B2 (en) 2018-02-26 2023-06-13 Neuwave Medical, Inc. Energy delivery devices with flexible and adjustable tips
US11832879B2 (en) 2019-03-08 2023-12-05 Neuwave Medical, Inc. Systems and methods for energy delivery
WO2021050767A1 (en) 2019-09-12 2021-03-18 Relievant Medsystems, Inc. Systems and methods for tissue modulation

Family Cites Families (7)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US3125096A (en) * 1964-03-17 Compressor
US3837347A (en) * 1972-04-20 1974-09-24 Electro Catheter Corp Inflatable balloon-type pacing probe
DE2407559C3 (en) * 1974-02-16 1982-01-21 Dornier System Gmbh, 7990 Friedrichshafen Heat probe
US4140130A (en) * 1977-05-31 1979-02-20 Storm Iii Frederick K Electrode structure for radio frequency localized heating of tumor bearing tissue
US4375220A (en) * 1980-05-09 1983-03-01 Matvias Fredrick M Microwave applicator with cooling mechanism for intracavitary treatment of cancer
WO1981003616A1 (en) * 1980-06-17 1981-12-24 T Sandhu Microwave antenna system for intracavitary insertion
US4469103A (en) * 1982-03-03 1984-09-04 Barrett Harold F Method of treating conditions such as tumors in living bodies

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