CA2025605A1 - Method of purifying human serum albumin - Google Patents

Method of purifying human serum albumin

Info

Publication number
CA2025605A1
CA2025605A1 CA2025605A CA2025605A CA2025605A1 CA 2025605 A1 CA2025605 A1 CA 2025605A1 CA 2025605 A CA2025605 A CA 2025605A CA 2025605 A CA2025605 A CA 2025605A CA 2025605 A1 CA2025605 A1 CA 2025605A1
Authority
CA
Canada
Prior art keywords
serum albumin
human serum
purifying human
purifying
acetyltryptophan
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Granted
Application number
CA2025605A
Other languages
French (fr)
Other versions
CA2025605C (en
Inventor
Wataru Ohtani
Akinori Sumi
Takao Ohmura
Yahiro Uemura
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Mitsubishi Pharma Corp
Original Assignee
Green Cross Corp Japan
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Family has litigation
First worldwide family litigation filed litigation Critical https://patents.darts-ip.com/?family=17051210&utm_source=google_patent&utm_medium=platform_link&utm_campaign=public_patent_search&patent=CA2025605(A1) "Global patent litigation dataset” by Darts-ip is licensed under a Creative Commons Attribution 4.0 International License.
Application filed by Green Cross Corp Japan filed Critical Green Cross Corp Japan
Publication of CA2025605A1 publication Critical patent/CA2025605A1/en
Application granted granted Critical
Publication of CA2025605C publication Critical patent/CA2025605C/en
Anticipated expiration legal-status Critical
Expired - Lifetime legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N15/00—Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
    • C12N15/09—Recombinant DNA-technology
    • C12N15/11—DNA or RNA fragments; Modified forms thereof; Non-coding nucleic acids having a biological activity
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • C07K14/76—Albumins
    • C07K14/765—Serum albumin, e.g. HSA

Abstract

A method of purifying human serum albumin which comprises subjecting human serum albumin-containing solution to heat treatment of about 50-70°C for 1-5 hours in the presence of acetyltryptophan and/or an organic carboxylic acid with 6-12 carbon atoms or a salt thereof.
CA002025605A 1989-09-18 1990-09-18 Method of purifying human serum albumin Expired - Lifetime CA2025605C (en)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
JPHEI.1-239877 1989-09-18
JP1239877A JPH0671434B2 (en) 1989-09-18 1989-09-18 Method for producing human serum albumin

Publications (2)

Publication Number Publication Date
CA2025605A1 true CA2025605A1 (en) 1991-03-19
CA2025605C CA2025605C (en) 2000-10-31

Family

ID=17051210

Family Applications (1)

Application Number Title Priority Date Filing Date
CA002025605A Expired - Lifetime CA2025605C (en) 1989-09-18 1990-09-18 Method of purifying human serum albumin

Country Status (8)

Country Link
US (1) US5132404A (en)
EP (1) EP0420007B1 (en)
JP (1) JPH0671434B2 (en)
KR (1) KR100199523B1 (en)
CA (1) CA2025605C (en)
DE (1) DE69005959T2 (en)
DK (1) DK0420007T3 (en)
ES (1) ES2062241T3 (en)

Families Citing this family (21)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JPH0671434B2 (en) * 1989-09-18 1994-09-14 株式会社ミドリ十字 Method for producing human serum albumin
US5268273A (en) * 1990-12-14 1993-12-07 Phillips Petroleum Company Pichia pastoris acid phosphatase gene, gene regions, signal sequence and expression vectors comprising same
JPH0671432B2 (en) * 1991-03-20 1994-09-14 株式会社ミドリ十字 Method for producing human serum albumin
PT681493E (en) * 1991-12-18 2000-12-29 Icu Medical Inc MEDICAL VALVE
US5521287A (en) * 1992-05-20 1996-05-28 The Green Cross Corporation Recombinant human serum albumin, process for producing the same and pharmaceutical preparation containing the same
US5440018A (en) * 1992-05-20 1995-08-08 The Green Cross Corporation Recombinant human serum albumin, process for producing the same and pharmaceutical preparation containing the same
US5728553A (en) 1992-09-23 1998-03-17 Delta Biotechnology Limited High purity albumin and method of producing
JPH07126182A (en) * 1993-10-27 1995-05-16 Green Cross Corp:The Sterilization of recombinant human serum albumin preparation
CA2138349A1 (en) * 1993-12-17 1995-06-18 Welfide Corporation Method for decoloring human serum albumin
US5561115A (en) * 1994-08-10 1996-10-01 Bayer Corporation Low temperature albumin fractionation using sodium caprylate as a partitioning agent
ES2211889T3 (en) * 1994-08-31 2004-07-16 Mitsubishi Pharma Corporation PROCEDURE FOR PURIFICATION OF RECOMBINANT SERUM ALBUMIN.
GB9902000D0 (en) 1999-01-30 1999-03-17 Delta Biotechnology Ltd Process
JP4798833B2 (en) * 2000-10-24 2011-10-19 一般財団法人化学及血清療法研究所 Method for producing human serum albumin including heat treatment step
EP1329460B1 (en) * 2000-10-24 2006-06-28 Juridical Foundation, The Chemo-Sero-Therapeutic Research Institute Method of monomerizing human serum albumin polymers
JP4798832B2 (en) 2000-10-24 2011-10-19 一般財団法人化学及血清療法研究所 Method for removing human serum albumin multimers
WO2003072123A1 (en) * 2002-02-28 2003-09-04 Nipro Corporation Stabilized albumin preparaions
JP4644604B2 (en) 2004-01-20 2011-03-02 一般財団法人化学及血清療法研究所 Method for producing human serum albumin by heat treatment in the presence of divalent cations
CA2634495A1 (en) * 2005-12-22 2007-06-28 Conjuchem Biotechnologies Inc. Process for the production of preformed conjugates of albumin and a therapeutic agent
EP2301561A4 (en) * 2008-05-15 2012-02-29 R Tech Ueno Ltd Pharmaceutical composition for treatment of dry eye and/or corneal/conjunctival disorders
KR101568360B1 (en) 2013-08-06 2015-11-12 이화여자대학교 산학협력단 Method for preparing thermal-stabilized human serum albumin
US11739166B2 (en) 2020-07-02 2023-08-29 Davol Inc. Reactive polysaccharide-based hemostatic agent

Family Cites Families (24)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US2444679A (en) * 1945-11-30 1948-07-06 Arthur J Shaukis Mailbox
US2765299A (en) * 1952-06-27 1956-10-02 Armour & Co Recovery of serum albumin
US3100737A (en) * 1958-02-05 1963-08-13 Auerswald Wilhelm Method of preparing a plasma protein solution free of active hepatitis virus and product produced thereby
FR2190437B1 (en) * 1972-07-05 1975-08-08 Merieux Inst
JPS5417002B2 (en) * 1974-02-18 1979-06-27
JPS5225019A (en) * 1975-08-19 1977-02-24 New Zealand Inventions Dev Production of serum albumin
JPS5312965A (en) * 1976-07-22 1978-02-06 Tatsuo Teraoka Method of manufacture of frp
DK25877A (en) * 1977-01-21 1978-08-15 Nordisk Insulinlab PROCEDURE FOR EXTRACTING PURE ALBUMIN FROM BLOOD PLASMA
JPS5417002A (en) * 1977-07-07 1979-02-08 Pioneer Electronic Corp Record player
US4426323A (en) * 1980-01-10 1984-01-17 Ionics, Incorporated Selected recovery of proteins from fermentation broths
JPS5795997A (en) * 1980-12-08 1982-06-15 Nippon Sekijiyuujishiya Removal of admixed protein from albumin-containing solution in presence of water-soluble high polymer
NZ207926A (en) * 1983-04-25 1988-04-29 Genentech Inc Use of yeast #a#-factor to assist in expression of proteins heterologus to yeast
US4613501A (en) * 1984-12-21 1986-09-23 New York Blood Center, Inc. Inactivation of viruses in labile blood derivatives
FR2579224B1 (en) * 1985-03-25 1987-05-22 Genetica PROCESS FOR THE MICROBIOLOGICAL PREPARATION OF HUMAN SERUM-ALBUMIN
US4675387A (en) * 1985-07-26 1987-06-23 E. I. Du Pont De Nemours And Company Method for extracting protein with organic acid
JPS62224284A (en) * 1986-03-25 1987-10-02 Agency Of Ind Science & Technol Bacterium
GB8613388D0 (en) * 1986-06-03 1986-07-09 Delta Biotechnology Ltd Induction of galactose regulated gene expression in yeast
US4723944A (en) * 1986-06-05 1988-02-09 Jensen Ole R Fluid collection receptacle with improved non-return valve
JPS62294621A (en) * 1986-06-13 1987-12-22 Green Cross Corp:The Method for recovering albumin
US4841023A (en) * 1986-06-25 1989-06-20 New York Blood Center, Inc. Inactivation of viruses in labile protein-containing compositions using fatty acids
GB8615701D0 (en) * 1986-06-27 1986-08-06 Delta Biotechnology Ltd Stable gene integration vector
JPH0811074B2 (en) * 1987-10-30 1996-02-07 財団法人化学及血清療法研究所 Recombinant plasmid incorporating a gene encoding prealbumin and method for producing prealbumin using the same
US4939176A (en) * 1988-12-20 1990-07-03 Miles Inc. Viral inactivation process
JPH0671434B2 (en) * 1989-09-18 1994-09-14 株式会社ミドリ十字 Method for producing human serum albumin

Also Published As

Publication number Publication date
US5132404A (en) 1992-07-21
JPH0671434B2 (en) 1994-09-14
EP0420007A1 (en) 1991-04-03
KR910006481A (en) 1991-04-29
ES2062241T3 (en) 1994-12-16
DE69005959T2 (en) 1994-06-16
DE69005959D1 (en) 1994-02-24
KR100199523B1 (en) 1999-06-15
JPH03103188A (en) 1991-04-30
DK0420007T3 (en) 1994-02-21
CA2025605C (en) 2000-10-31
EP0420007B1 (en) 1994-01-12

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Legal Events

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