CA2042289A1 - Taste masking and sustained release coatings for pharmaceuticals - Google Patents

Taste masking and sustained release coatings for pharmaceuticals

Info

Publication number
CA2042289A1
CA2042289A1 CA2042289A CA2042289A CA2042289A1 CA 2042289 A1 CA2042289 A1 CA 2042289A1 CA 2042289 A CA2042289 A CA 2042289A CA 2042289 A CA2042289 A CA 2042289A CA 2042289 A1 CA2042289 A1 CA 2042289A1
Authority
CA
Canada
Prior art keywords
sustained release
pharmaceuticals
taste masking
release coatings
tablets
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Granted
Application number
CA2042289A
Other languages
French (fr)
Other versions
CA2042289C (en
Inventor
Edward J. Roche
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Johnson and Johnson Consumer Inc
Original Assignee
McNeil PPC Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by McNeil PPC Inc filed Critical McNeil PPC Inc
Publication of CA2042289A1 publication Critical patent/CA2042289A1/en
Application granted granted Critical
Publication of CA2042289C publication Critical patent/CA2042289C/en
Anticipated expiration legal-status Critical
Expired - Lifetime legal-status Critical Current

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/48—Preparations in capsules, e.g. of gelatin, of chocolate
    • A61K9/50—Microcapsules having a gas, liquid or semi-solid filling; Solid microparticles or pellets surrounded by a distinct coating layer, e.g. coated microspheres, coated drug crystals
    • A61K9/5005—Wall or coating material
    • A61K9/5021—Organic macromolecular compounds
    • A61K9/5036—Polysaccharides, e.g. gums, alginate; Cyclodextrin
    • A61K9/5042—Cellulose; Cellulose derivatives, e.g. phthalate or acetate succinate esters of hydroxypropyl methylcellulose
    • A61K9/5047—Cellulose ethers containing no ester groups, e.g. hydroxypropyl methylcellulose
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/0012—Galenical forms characterised by the site of application
    • A61K9/0053—Mouth and digestive tract, i.e. intraoral and peroral administration
    • A61K9/0056—Mouth soluble or dispersible forms; Suckable, eatable, chewable coherent forms; Forms rapidly disintegrating in the mouth; Lozenges; Lollipops; Bite capsules; Baked products; Baits or other oral forms for animals
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/48—Preparations in capsules, e.g. of gelatin, of chocolate
    • A61K9/50—Microcapsules having a gas, liquid or semi-solid filling; Solid microparticles or pellets surrounded by a distinct coating layer, e.g. coated microspheres, coated drug crystals
    • A61K9/5005—Wall or coating material
    • A61K9/5021—Organic macromolecular compounds
    • A61K9/5036—Polysaccharides, e.g. gums, alginate; Cyclodextrin
    • A61K9/5042—Cellulose; Cellulose derivatives, e.g. phthalate or acetate succinate esters of hydroxypropyl methylcellulose

Abstract

Chewable medicament tablets are made from coated granules of a medicament wherein the coating on said granules comprises a blend of cellulose acetate and/or cellulose acetate butyrate and hydroxypropyl cellulose and a process for making such tablets and a method of providing sustained release of medicaments utilizing such coated granules in a tablet.
CA002042289A 1990-05-23 1991-05-10 Taste masking and sustained release coatings for pharmaceuticals Expired - Lifetime CA2042289C (en)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US528,003 1990-05-23
US07/528,003 US5075114A (en) 1990-05-23 1990-05-23 Taste masking and sustained release coatings for pharmaceuticals
IN325CA1991 IN172428B (en) 1990-05-23 1991-04-29

Publications (2)

Publication Number Publication Date
CA2042289A1 true CA2042289A1 (en) 1991-11-24
CA2042289C CA2042289C (en) 1998-12-08

Family

ID=26324259

Family Applications (1)

Application Number Title Priority Date Filing Date
CA002042289A Expired - Lifetime CA2042289C (en) 1990-05-23 1991-05-10 Taste masking and sustained release coatings for pharmaceuticals

Country Status (11)

Country Link
US (1) US5075114A (en)
EP (1) EP0459695B1 (en)
JP (1) JP3157190B2 (en)
AU (1) AU639334B2 (en)
CA (1) CA2042289C (en)
ES (1) ES2073677T3 (en)
GR (1) GR1002092B (en)
IE (1) IE67062B1 (en)
IN (1) IN172428B (en)
NZ (1) NZ238131A (en)
PT (1) PT97739B (en)

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Publication number Priority date Publication date Assignee Title
CN113453563A (en) * 2019-02-20 2021-09-28 三得利控股株式会社 Oral composition containing protein and method for improving flavor of oral composition containing protein

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NZ226822A (en) * 1987-11-16 1990-03-27 Mcneil Consumer Prod Chewable medicament tablet containing means for taste masking
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Cited By (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN113453563A (en) * 2019-02-20 2021-09-28 三得利控股株式会社 Oral composition containing protein and method for improving flavor of oral composition containing protein

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EP0459695B1 (en) 1995-03-15
JPH06316536A (en) 1994-11-15
CA2042289C (en) 1998-12-08
NZ238131A (en) 1992-09-25
PT97739A (en) 1992-03-31
AU7723491A (en) 1991-11-28
ES2073677T3 (en) 1995-08-16
EP0459695A1 (en) 1991-12-04
GR910100204A (en) 1992-07-30
AU639334B2 (en) 1993-07-22
US5075114A (en) 1991-12-24
IE911752A1 (en) 1991-12-04
IE67062B1 (en) 1996-02-21
IN172428B (en) 1993-07-24
GR1002092B (en) 1995-12-28
JP3157190B2 (en) 2001-04-16

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