CA2056619A1 - Method of inactivation of viral and bacterial blood contaminants - Google Patents

Method of inactivation of viral and bacterial blood contaminants

Info

Publication number
CA2056619A1
CA2056619A1 CA002056619A CA2056619A CA2056619A1 CA 2056619 A1 CA2056619 A1 CA 2056619A1 CA 002056619 A CA002056619 A CA 002056619A CA 2056619 A CA2056619 A CA 2056619A CA 2056619 A1 CA2056619 A1 CA 2056619A1
Authority
CA
Canada
Prior art keywords
viral
inactivation
bacterial blood
blood contaminants
protein fractions
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Granted
Application number
CA002056619A
Other languages
French (fr)
Other versions
CA2056619C (en
Inventor
Roger W. Hackett
Raymond P. Goodrich, Jr.
Marjan Van Borssum Waalkes
Victoria A. Wong
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Baxter International Inc
Original Assignee
Roger W. Hackett
Raymond P. Goodrich, Jr.
Marjan Van Borssum Waalkes
Victoria A. Wong
Cryopharm Corporation
Credit Management Solutions, Inc.
Baxter International Inc.
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Roger W. Hackett, Raymond P. Goodrich, Jr., Marjan Van Borssum Waalkes, Victoria A. Wong, Cryopharm Corporation, Credit Management Solutions, Inc., Baxter International Inc. filed Critical Roger W. Hackett
Priority claimed from PCT/US1991/002504 external-priority patent/WO1991016060A1/en
Publication of CA2056619A1 publication Critical patent/CA2056619A1/en
Application granted granted Critical
Publication of CA2056619C publication Critical patent/CA2056619C/en
Anticipated expiration legal-status Critical
Expired - Fee Related legal-status Critical Current

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
    • A61L2/00—Methods or apparatus for disinfecting or sterilising materials or objects other than foodstuffs or contact lenses; Accessories therefor
    • A61L2/0005—Methods or apparatus for disinfecting or sterilising materials or objects other than foodstuffs or contact lenses; Accessories therefor for pharmaceuticals, biologicals or living parts
    • A61L2/0011—Methods or apparatus for disinfecting or sterilising materials or objects other than foodstuffs or contact lenses; Accessories therefor for pharmaceuticals, biologicals or living parts using physical methods
    • A61L2/0029—Radiation
    • A61L2/0035—Gamma radiation
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
    • A61L2/00—Methods or apparatus for disinfecting or sterilising materials or objects other than foodstuffs or contact lenses; Accessories therefor
    • A61L2/0005—Methods or apparatus for disinfecting or sterilising materials or objects other than foodstuffs or contact lenses; Accessories therefor for pharmaceuticals, biologicals or living parts
    • A61L2/0011—Methods or apparatus for disinfecting or sterilising materials or objects other than foodstuffs or contact lenses; Accessories therefor for pharmaceuticals, biologicals or living parts using physical methods
    • A61L2/0029—Radiation
    • A61L2/0041—X-rays
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
    • A61L2202/00—Aspects relating to methods or apparatus for disinfecting or sterilising materials or objects
    • A61L2202/20—Targets to be treated
    • A61L2202/22—Blood or products thereof

Abstract

A method is provided for inactivating viral and/or bacterial contamination in blood cellular matter, such as erythrocytes and platelets, or protein fractions. The cells or protein fractions are mixed with chemical sensitizers and irradiated with, for ex-ample, gamma or X-ray radiation.
CA002056619A 1990-04-16 1991-04-16 Method of inactivation of viral and bacterial blood contaminants Expired - Fee Related CA2056619C (en)

Applications Claiming Priority (5)

Application Number Priority Date Filing Date Title
US51023490A 1990-04-16 1990-04-16
US510,234 1990-04-16
US63227790A 1990-12-20 1990-12-20
US632,277 1990-12-20
PCT/US1991/002504 WO1991016060A1 (en) 1990-04-16 1991-04-16 Method of inactivation of viral and bacterial blood contaminants

Publications (2)

Publication Number Publication Date
CA2056619A1 true CA2056619A1 (en) 1991-10-17
CA2056619C CA2056619C (en) 2002-07-30

Family

ID=27056837

Family Applications (1)

Application Number Title Priority Date Filing Date
CA002056619A Expired - Fee Related CA2056619C (en) 1990-04-16 1991-04-16 Method of inactivation of viral and bacterial blood contaminants

Country Status (2)

Country Link
JP (1) JP3373201B2 (en)
CA (1) CA2056619C (en)

Cited By (9)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US6171549B1 (en) 1993-07-22 2001-01-09 Sterisure, Inc. Method for sterilizing products
US6682695B2 (en) 2001-03-23 2004-01-27 Clearant, Inc. Methods for sterilizing biological materials by multiple rates
US6696060B2 (en) 2001-06-14 2004-02-24 Clearant, Inc. Methods for sterilizing preparations of monoclonal immunoglobulins
US6749851B2 (en) 2001-08-31 2004-06-15 Clearant, Inc. Methods for sterilizing preparations of digestive enzymes
US6783968B2 (en) 2001-09-24 2004-08-31 Clearant, Inc. Methods for sterilizing preparations of glycosidases
US6908591B2 (en) 2002-07-18 2005-06-21 Clearant, Inc. Methods for sterilizing biological materials by irradiation over a temperature gradient
US6946098B2 (en) 2001-08-10 2005-09-20 Clearant, Inc. Methods for sterilizing biological materials
US7252799B2 (en) 2001-08-31 2007-08-07 Clearant, Inc. Methods for sterilizing preparations containing albumin
US7848487B2 (en) 2001-09-24 2010-12-07 Clearant, Inc. Methods for sterilizing biological materials containing non-aqueous solvents

Cited By (11)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US6171549B1 (en) 1993-07-22 2001-01-09 Sterisure, Inc. Method for sterilizing products
US6346216B1 (en) 1993-07-22 2002-02-12 Clearant, Inc. Method for sterilizing products
US6635222B2 (en) 1993-07-22 2003-10-21 Clearant, Inc. Method of sterilizing products
US6682695B2 (en) 2001-03-23 2004-01-27 Clearant, Inc. Methods for sterilizing biological materials by multiple rates
US6696060B2 (en) 2001-06-14 2004-02-24 Clearant, Inc. Methods for sterilizing preparations of monoclonal immunoglobulins
US6946098B2 (en) 2001-08-10 2005-09-20 Clearant, Inc. Methods for sterilizing biological materials
US6749851B2 (en) 2001-08-31 2004-06-15 Clearant, Inc. Methods for sterilizing preparations of digestive enzymes
US7252799B2 (en) 2001-08-31 2007-08-07 Clearant, Inc. Methods for sterilizing preparations containing albumin
US6783968B2 (en) 2001-09-24 2004-08-31 Clearant, Inc. Methods for sterilizing preparations of glycosidases
US7848487B2 (en) 2001-09-24 2010-12-07 Clearant, Inc. Methods for sterilizing biological materials containing non-aqueous solvents
US6908591B2 (en) 2002-07-18 2005-06-21 Clearant, Inc. Methods for sterilizing biological materials by irradiation over a temperature gradient

Also Published As

Publication number Publication date
JPH05500971A (en) 1993-02-25
JP3373201B2 (en) 2003-02-04
CA2056619C (en) 2002-07-30

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Legal Events

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