CA2064861A1 - Galenique injectable a effet retarde - Google Patents
Galenique injectable a effet retardeInfo
- Publication number
- CA2064861A1 CA2064861A1 CA2064861A CA2064861A CA2064861A1 CA 2064861 A1 CA2064861 A1 CA 2064861A1 CA 2064861 A CA2064861 A CA 2064861A CA 2064861 A CA2064861 A CA 2064861A CA 2064861 A1 CA2064861 A1 CA 2064861A1
- Authority
- CA
- Canada
- Prior art keywords
- galenical
- nervous system
- slow
- recipient
- injectable slow
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Granted
Links
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/14—Particulate form, e.g. powders, Processes for size reducing of pure drugs or the resulting products, Pure drug nanoparticles
- A61K9/16—Agglomerates; Granulates; Microbeadlets ; Microspheres; Pellets; Solid products obtained by spray drying, spray freeze drying, spray congealing,(multiple) emulsion solvent evaporation or extraction
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/14—Particulate form, e.g. powders, Processes for size reducing of pure drugs or the resulting products, Pure drug nanoparticles
- A61K9/16—Agglomerates; Granulates; Microbeadlets ; Microspheres; Pellets; Solid products obtained by spray drying, spray freeze drying, spray congealing,(multiple) emulsion solvent evaporation or extraction
- A61K9/1605—Excipients; Inactive ingredients
- A61K9/1617—Organic compounds, e.g. phospholipids, fats
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/48—Preparations in capsules, e.g. of gelatin, of chocolate
- A61K9/50—Microcapsules having a gas, liquid or semi-solid filling; Solid microparticles or pellets surrounded by a distinct coating layer, e.g. coated microspheres, coated drug crystals
Abstract
Formulation à libération retardée destinée à l'administration par injection parentérale, constituée de microsphères calibrées solides (5-300 µm) comprenant une substance pharmaceutiquement active (par exemple: morphine) contenue dans des structures sphériques formées par une ou plusieurs substances-support pharmacologiquement inactives (par exemple: cholestérol) présentes naturellement dans l'organisme receveur, pharmacodynamiquement inactives aux doses d'administration de ladite forme galénique, ayant un point de fusion supérieur à 60 °C et stables à l'état solide dans le milieu physiologique receveur. La forme galénique permet de ralentir et de prolonger l'effet de substances actives trop rapidement solubles en milieu physiologiques (agissant sur le système nerveux central ou neuro-végétatif, comme vasodilatateurs, antihistaminiques, hormones, anticonceptifs...).
Applications Claiming Priority (3)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
FR9007417 | 1990-06-14 | ||
FR9007417A FR2663224B1 (fr) | 1990-06-14 | 1990-06-14 | Forme galenique parenterale. |
PCT/EP1991/001097 WO1991019485A1 (fr) | 1990-06-14 | 1991-06-12 | Forme galenique injectable retardee |
Publications (2)
Publication Number | Publication Date |
---|---|
CA2064861A1 true CA2064861A1 (fr) | 1991-12-15 |
CA2064861C CA2064861C (fr) | 2000-08-01 |
Family
ID=9397599
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
CA002064861A Expired - Fee Related CA2064861C (fr) | 1990-06-14 | 1991-06-12 | Galenique injectable a effet retarde |
Country Status (33)
Country | Link |
---|---|
US (1) | US5643604A (fr) |
EP (1) | EP0487674B1 (fr) |
JP (1) | JP2690398B2 (fr) |
KR (1) | KR0157438B1 (fr) |
CN (1) | CN1058608C (fr) |
AT (1) | ATE117546T1 (fr) |
AU (1) | AU643540B2 (fr) |
BG (1) | BG61178B1 (fr) |
BR (1) | BR9105782A (fr) |
CA (1) | CA2064861C (fr) |
CZ (1) | CZ286199B6 (fr) |
DE (1) | DE69107026T2 (fr) |
DK (1) | DK0487674T3 (fr) |
ES (1) | ES2068592T3 (fr) |
FI (1) | FI107697B (fr) |
FR (1) | FR2663224B1 (fr) |
GR (1) | GR3015809T3 (fr) |
HU (1) | HU219461B (fr) |
IE (1) | IE69172B1 (fr) |
IL (1) | IL98458A (fr) |
NO (2) | NO920576L (fr) |
NZ (1) | NZ238543A (fr) |
PH (1) | PH30243A (fr) |
PL (1) | PL167177B1 (fr) |
PT (1) | PT97976B (fr) |
RO (1) | RO110198B1 (fr) |
RU (1) | RU2095055C1 (fr) |
SK (1) | SK279867B6 (fr) |
TN (1) | TNSN91047A1 (fr) |
TW (1) | TW205511B (fr) |
UY (1) | UY23239A1 (fr) |
WO (1) | WO1991019485A1 (fr) |
ZA (1) | ZA914549B (fr) |
Families Citing this family (28)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US6090925A (en) | 1993-03-09 | 2000-07-18 | Epic Therapeutics, Inc. | Macromolecular microparticles and methods of production and use |
US5981719A (en) | 1993-03-09 | 1999-11-09 | Epic Therapeutics, Inc. | Macromolecular microparticles and methods of production and use |
US5993856A (en) * | 1997-01-24 | 1999-11-30 | Femmepharma | Pharmaceutical preparations and methods for their administration |
US6416778B1 (en) | 1997-01-24 | 2002-07-09 | Femmepharma | Pharmaceutical preparations and methods for their regional administration |
US6287693B1 (en) * | 1998-02-25 | 2001-09-11 | John Claude Savoir | Stable shaped particles of crystalline organic compounds |
GB9819272D0 (en) * | 1998-09-03 | 1998-10-28 | Andaris Ltd | Microparticles |
US6495535B1 (en) | 1999-03-26 | 2002-12-17 | Pozen Inc. | High potency dihydroergotamine compositions |
ATE288687T1 (de) * | 2001-09-27 | 2005-02-15 | Cognis Deutschland Gmbh | Kugelförmige sterinzubereitungen, deren herstellung und verwendung |
EP1448228A4 (fr) * | 2001-10-24 | 2007-01-24 | Marco Pappagallo | Traitement de la douleur postoperatoire |
CA2471400A1 (fr) * | 2001-12-20 | 2003-07-03 | Femmepharma, Inc. | Administration de medicaments par voie vaginale |
MXPA05006994A (es) * | 2002-12-27 | 2005-10-18 | Diobex Inc | Composiciones y metodos para la prevencion y el control de hipoglucemia inducida por insulina. |
US7655618B2 (en) * | 2002-12-27 | 2010-02-02 | Diobex, Inc. | Compositions and methods for the prevention and control of insulin-induced hypoglycemia |
US9173836B2 (en) | 2003-01-02 | 2015-11-03 | FemmeParma Holding Company, Inc. | Pharmaceutical preparations for treatments of diseases and disorders of the breast |
MXPA05007266A (es) * | 2003-01-02 | 2006-01-17 | Femmepharma Holding Co Inc | Preparaciones farmaceuticas para tratamientos de enfermedades y trastornos del seno. |
EA026709B1 (ru) * | 2003-06-13 | 2017-05-31 | Джон Клод Савуар | Способ получения композиции эстрадиола с медленным высвобождением (варианты) |
US7413690B1 (en) | 2003-10-29 | 2008-08-19 | The University Of Mississippi | Process and apparatus for producing spherical pellets using molten solid matrices |
SI1838716T1 (sl) | 2005-01-05 | 2011-10-28 | Lilly Co Eli | Olanzapin pamoat dihidrat |
WO2007072491A2 (fr) * | 2005-12-21 | 2007-06-28 | Baskaran Chandrasekar | Formulation pharmaceutique a liberation prolongee et traitement des cardiopathies ischemiques par l’administration de celle-ci |
MX2009005478A (es) | 2006-11-27 | 2009-08-12 | Lundbeck & Co As H | Derivados de heteroarilamida. |
EP2104489A2 (fr) * | 2006-12-26 | 2009-09-30 | FemmePharma Holding Company, Inc. | Administration topique de danazol |
CA2721509A1 (fr) * | 2008-04-14 | 2009-10-22 | Posi Visionary Solutions Llp | Methode et composition pharmaceutique permettant d'obtenir les taux plasmatiques de progesterone requis pour differentes indications therapeutiques |
US20110003000A1 (en) * | 2009-07-06 | 2011-01-06 | Femmepharma Holding Company, Inc. | Transvaginal Delivery of Drugs |
UY33103A (es) | 2009-12-15 | 2011-07-29 | Techsphere S A De C V | Formulacion farmaceutica parenteral en suspension, de liberacion sostenida, en dosis baja y ultra baja, en terapia hormonal en el sindrome climaterico |
CN102753181B (zh) * | 2010-01-14 | 2014-09-17 | 优麦克里尼穆德公司 | 具有改进的储存特性和溶解度特性的包含3-β-羟基-5-α-孕烷-20-酮的药物组合物 |
RU2576236C1 (ru) * | 2014-08-22 | 2016-02-27 | Александр Александрович Кролевец | Способ получения нанокапсул антибиотиков в агар-агаре |
RU2577689C1 (ru) * | 2014-08-26 | 2016-03-20 | Александр Александрович Кролевец | Способ получения нанокапсул антибиотиков в агар-агаре |
RU2578408C1 (ru) * | 2014-09-10 | 2016-03-27 | Александр Александрович Кролевец | Способ получения нанокапсул алкалоидов |
ITUB20153652A1 (it) * | 2015-09-16 | 2017-03-16 | Fatro Spa | Microsfere contenenti lattoni macrociclici antielminitici |
Family Cites Families (29)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
BE744162A (fr) * | 1969-01-16 | 1970-06-15 | Fuji Photo Film Co Ltd | Procede d'encapsulage |
US3773919A (en) * | 1969-10-23 | 1973-11-20 | Du Pont | Polylactide-drug mixtures |
US3937668A (en) * | 1970-07-15 | 1976-02-10 | Ilse Zolle | Method for incorporating substances into protein microspheres |
DK123067B (da) * | 1970-09-25 | 1972-05-15 | Niro Atomizer As | Fremgangsmåde til behandling af et pulverformigt, fedtholdigt mælkeprodukt. |
JPS5017525A (fr) * | 1973-06-14 | 1975-02-24 | ||
US3982537A (en) * | 1974-12-30 | 1976-09-28 | Louis Bucalo | Dynamic implants and method for implanting the same |
CA1077842A (fr) * | 1975-10-09 | 1980-05-20 | Minnesota Mining And Manufacturing Company | Excipient albumineux pour medicament |
IT1202370B (it) * | 1976-07-12 | 1989-02-09 | Hoffmann La Roche | Soluzioni inietabili in cui l'atti vita' emolitica degli agenti di formazione di micelle naturali e' evitata mediante l'aggiunta di lipoidi e relativi prodotti |
US4357259A (en) * | 1977-08-01 | 1982-11-02 | Northwestern University | Method of incorporating water-soluble heat-sensitive therapeutic agents in albumin microspheres |
US4244949A (en) * | 1978-04-06 | 1981-01-13 | The Population Council, Inc. | Manufacture of long term contraceptive implant |
US4331654A (en) * | 1980-06-13 | 1982-05-25 | Eli Lilly And Company | Magnetically-localizable, biodegradable lipid microspheres |
US4384975A (en) * | 1980-06-13 | 1983-05-24 | Sandoz, Inc. | Process for preparation of microspheres |
US4349530A (en) * | 1980-12-11 | 1982-09-14 | The Ohio State University | Implants, microbeads, microcapsules, preparation thereof and method of administering a biologically-active substance to an animal |
FR2524312B1 (fr) * | 1982-04-01 | 1985-10-04 | Tech Cuir Centre | Nouvelles formes de micro-encapsulation de substances medicamenteuses par des couches homogenes de collagene natif |
US4492720A (en) * | 1983-11-15 | 1985-01-08 | Benjamin Mosier | Method of preparing microspheres for intravascular delivery |
US4963367A (en) * | 1984-04-27 | 1990-10-16 | Medaphore, Inc. | Drug delivery compositions and methods |
JPS61174940A (ja) * | 1985-01-29 | 1986-08-06 | Oogawara Kakoki Kk | ワックス類コーテイング単核状マイクロカプセルおよびその製造方法 |
US4675173A (en) * | 1985-05-08 | 1987-06-23 | Molecular Biosystems, Inc. | Method of magnetic resonance imaging of the liver and spleen |
IL79407A (en) * | 1985-08-01 | 1991-03-10 | Theragenics Corp | System and method for delivering insoluble material into a living body |
US4837381A (en) * | 1986-08-11 | 1989-06-06 | American Cyanamid Company | Compositions for parenteral administration and their use |
EP0257368B1 (fr) * | 1986-08-11 | 1992-03-25 | American Cyanamid Company | Compositions pour l'administration parentérale et leur application |
CA1319886C (fr) * | 1987-02-03 | 1993-07-06 | Alberto Ferro | Solutions de micelles mixtes |
US4892734A (en) * | 1987-04-06 | 1990-01-09 | Endocon, Inc. | Dispensing paste for forming medicinal pellets |
WO1988007816A1 (fr) * | 1987-04-06 | 1988-10-20 | Endocon, Inc. | Implants medicinaux fusionnes a coulee rapide |
US4748024A (en) * | 1987-04-06 | 1988-05-31 | Endocon, Inc. | Flash flow fused medicinal implants |
EP0366058A3 (fr) * | 1988-10-27 | 1991-03-20 | Abbott Laboratories | Dispositif de délivrance à libération contrôlée, procédé de préparation du dispositif et méthode d'utilisation du dispositif |
US5019400A (en) * | 1989-05-01 | 1991-05-28 | Enzytech, Inc. | Very low temperature casting of controlled release microspheres |
US5085864A (en) * | 1989-10-30 | 1992-02-04 | Abbott Laboratories | Injectable formulation for lipophilic drugs |
FR2663223B1 (fr) * | 1990-06-14 | 1994-12-02 | Af Aplicaciones Far Lab | Forme galenique parenterale. |
-
1990
- 1990-06-14 FR FR9007417A patent/FR2663224B1/fr not_active Expired - Fee Related
-
1991
- 1991-06-11 IL IL9845891A patent/IL98458A/en not_active IP Right Cessation
- 1991-06-12 AT AT91910873T patent/ATE117546T1/de not_active IP Right Cessation
- 1991-06-12 RU SU915011663A patent/RU2095055C1/ru active
- 1991-06-12 AU AU80667/91A patent/AU643540B2/en not_active Ceased
- 1991-06-12 HU HU9200775A patent/HU219461B/hu not_active IP Right Cessation
- 1991-06-12 DE DE69107026T patent/DE69107026T2/de not_active Expired - Fee Related
- 1991-06-12 RO RO92-200136A patent/RO110198B1/ro unknown
- 1991-06-12 CA CA002064861A patent/CA2064861C/fr not_active Expired - Fee Related
- 1991-06-12 BR BR919105782A patent/BR9105782A/pt not_active Application Discontinuation
- 1991-06-12 ES ES91910873T patent/ES2068592T3/es not_active Expired - Lifetime
- 1991-06-12 EP EP91910873A patent/EP0487674B1/fr not_active Expired - Lifetime
- 1991-06-12 KR KR1019920700315A patent/KR0157438B1/ko not_active IP Right Cessation
- 1991-06-12 WO PCT/EP1991/001097 patent/WO1991019485A1/fr active IP Right Grant
- 1991-06-12 DK DK91910873.8T patent/DK0487674T3/da active
- 1991-06-12 JP JP3510713A patent/JP2690398B2/ja not_active Expired - Lifetime
- 1991-06-13 IE IE201891A patent/IE69172B1/en not_active IP Right Cessation
- 1991-06-13 UY UY23239A patent/UY23239A1/es not_active IP Right Cessation
- 1991-06-13 CZ CS19911815A patent/CZ286199B6/cs not_active IP Right Cessation
- 1991-06-13 SK SK1815-91A patent/SK279867B6/sk unknown
- 1991-06-14 TN TNTNSN91047A patent/TNSN91047A1/fr unknown
- 1991-06-14 TW TW080104715A patent/TW205511B/zh active
- 1991-06-14 NZ NZ238543A patent/NZ238543A/en not_active IP Right Cessation
- 1991-06-14 ZA ZA914549A patent/ZA914549B/xx unknown
- 1991-06-14 PL PL91290678A patent/PL167177B1/pl not_active IP Right Cessation
- 1991-06-14 PH PH42634A patent/PH30243A/en unknown
- 1991-06-14 PT PT97976A patent/PT97976B/pt not_active IP Right Cessation
- 1991-06-14 CN CN91104858A patent/CN1058608C/zh not_active Expired - Fee Related
-
1992
- 1992-02-13 NO NO92920576A patent/NO920576L/no unknown
- 1992-02-13 NO NO920576A patent/NO302927B1/no not_active IP Right Cessation
- 1992-02-13 BG BG95911A patent/BG61178B1/bg unknown
- 1992-02-14 FI FI920661A patent/FI107697B/fi active
-
1993
- 1993-07-14 US US08/094,579 patent/US5643604A/en not_active Expired - Lifetime
-
1995
- 1995-04-17 GR GR950400939T patent/GR3015809T3/el unknown
Also Published As
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Legal Events
Date | Code | Title | Description |
---|---|---|---|
EEER | Examination request | ||
MKLA | Lapsed |