CA2081666A1 - Internal tissue medication permeating apparatus and method - Google Patents

Internal tissue medication permeating apparatus and method

Info

Publication number
CA2081666A1
CA2081666A1 CA2081666A CA2081666A CA2081666A1 CA 2081666 A1 CA2081666 A1 CA 2081666A1 CA 2081666 A CA2081666 A CA 2081666A CA 2081666 A CA2081666 A CA 2081666A CA 2081666 A1 CA2081666 A1 CA 2081666A1
Authority
CA
Canada
Prior art keywords
medication
internal tissue
patient
permeating
stenosis
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Granted
Application number
CA2081666A
Other languages
French (fr)
Other versions
CA2081666C (en
Inventor
Andrew Jonathan Feiring
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Individual
Original Assignee
Individual
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Individual filed Critical Individual
Publication of CA2081666A1 publication Critical patent/CA2081666A1/en
Application granted granted Critical
Publication of CA2081666C publication Critical patent/CA2081666C/en
Anticipated expiration legal-status Critical
Expired - Fee Related legal-status Critical Current

Links

Classifications

    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61MDEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M25/00Catheters; Hollow probes
    • A61M25/10Balloon catheters
    • A61M25/104Balloon catheters used for angioplasty
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61FFILTERS IMPLANTABLE INTO BLOOD VESSELS; PROSTHESES; DEVICES PROVIDING PATENCY TO, OR PREVENTING COLLAPSING OF, TUBULAR STRUCTURES OF THE BODY, e.g. STENTS; ORTHOPAEDIC, NURSING OR CONTRACEPTIVE DEVICES; FOMENTATION; TREATMENT OR PROTECTION OF EYES OR EARS; BANDAGES, DRESSINGS OR ABSORBENT PADS; FIRST-AID KITS
    • A61F11/00Methods or devices for treatment of the ears or hearing sense; Non-electric hearing aids; Methods or devices for enabling ear patients to achieve auditory perception through physiological senses other than hearing sense; Protective devices for the ears, carried on the body or in the hand
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61MDEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M16/00Devices for influencing the respiratory system of patients by gas treatment, e.g. mouth-to-mouth respiration; Tracheal tubes
    • A61M16/04Tracheal tubes
    • A61M16/0434Cuffs
    • A61M16/0436Special fillings therefor
    • A61M16/0438Liquid-filled
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61MDEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M16/00Devices for influencing the respiratory system of patients by gas treatment, e.g. mouth-to-mouth respiration; Tracheal tubes
    • A61M16/04Tracheal tubes
    • A61M16/0475Tracheal tubes having openings in the tube
    • A61M16/0477Tracheal tubes having openings in the tube with incorporated means for delivering or removing fluids
    • A61M16/0481Tracheal tubes having openings in the tube with incorporated means for delivering or removing fluids through the cuff wall
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61NELECTROTHERAPY; MAGNETOTHERAPY; RADIATION THERAPY; ULTRASOUND THERAPY
    • A61N1/00Electrotherapy; Circuits therefor
    • A61N1/18Applying electric currents by contact electrodes
    • A61N1/20Applying electric currents by contact electrodes continuous direct currents
    • A61N1/30Apparatus for iontophoresis, i.e. transfer of media in ionic state by an electromotoric force into the body, or cataphoresis
    • A61N1/303Constructional details
    • A61N1/306Arrangements where at least part of the apparatus is introduced into the body
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61MDEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M25/00Catheters; Hollow probes
    • A61M25/10Balloon catheters
    • A61M2025/1043Balloon catheters with special features or adapted for special applications
    • A61M2025/105Balloon catheters with special features or adapted for special applications having a balloon suitable for drug delivery, e.g. by using holes for delivery, drug coating or membranes
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61MDEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M37/00Other apparatus for introducing media into the body; Percutany, i.e. introducing medicines into the body by diffusion through the skin
    • A61M2037/0007Other apparatus for introducing media into the body; Percutany, i.e. introducing medicines into the body by diffusion through the skin having means for enhancing the permeation of substances through the epidermis, e.g. using suction or depression, electric or magnetic fields, sound waves or chemical agents
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61MDEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M37/00Other apparatus for introducing media into the body; Percutany, i.e. introducing medicines into the body by diffusion through the skin

Abstract

An apparatus is described for selectively inducing the permeation of a liquid to a region of a stenosis in a blood vessel in a patient's body. The apparatus includes an external electrode (13) for positioning outside the patient's body and a catheter (10) carrying an internal electrode (38) for positioning adjacent a stenosis in a blood vessel in the body. The apparatus includes means for inducing an electric field between the internal electrode (38) and the external electrode (13) which is pulsed in phase with the patient's cardiac rhythm. <IMAGE>
CA002081666A 1990-05-07 1991-05-06 Internal tissue medication permeating apparatus and method Expired - Fee Related CA2081666C (en)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US07520033 US5236413B1 (en) 1990-05-07 1990-05-07 Method and apparatus for inducing the permeation of medication into internal tissue
US520,033 1990-05-07
PCT/US1991/003091 WO1991016945A1 (en) 1990-05-07 1991-05-06 Internal tissue medication permeating apparatus and method

Publications (2)

Publication Number Publication Date
CA2081666A1 true CA2081666A1 (en) 1991-11-08
CA2081666C CA2081666C (en) 1998-12-29

Family

ID=24070921

Family Applications (1)

Application Number Title Priority Date Filing Date
CA002081666A Expired - Fee Related CA2081666C (en) 1990-05-07 1991-05-06 Internal tissue medication permeating apparatus and method

Country Status (8)

Country Link
US (7) US5236413B1 (en)
EP (2) EP0527920B1 (en)
JP (1) JP3372250B2 (en)
AT (2) ATE207375T1 (en)
AU (1) AU642020B2 (en)
CA (1) CA2081666C (en)
DE (2) DE69132787T2 (en)
WO (1) WO1991016945A1 (en)

Families Citing this family (473)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5599296A (en) * 1991-02-14 1997-02-04 Wayne State University Apparatus and method of delivery of gas-supersaturated liquids
US5236413B1 (en) * 1990-05-07 1996-06-18 Andrew J Feiring Method and apparatus for inducing the permeation of medication into internal tissue
US5499971A (en) * 1990-06-15 1996-03-19 Cortrak Medical, Inc. Method for iontophoretically delivering drug adjacent to a heart
US5498238A (en) * 1990-06-15 1996-03-12 Cortrak Medical, Inc. Simultaneous angioplasty and phoretic drug delivery
DE69110467T2 (en) * 1990-06-15 1996-02-01 Cortrak Medical Inc DEVICE FOR DISPENSING MEDICINES.
US5458568A (en) * 1991-05-24 1995-10-17 Cortrak Medical, Inc. Porous balloon for selective dilatation and drug delivery
US5558644A (en) * 1991-07-16 1996-09-24 Heartport, Inc. Retrograde delivery catheter and method for inducing cardioplegic arrest
US5584803A (en) 1991-07-16 1996-12-17 Heartport, Inc. System for cardiac procedures
US6482171B1 (en) 1991-07-16 2002-11-19 Heartport, Inc. Multi-lumen catheter
US5769812A (en) 1991-07-16 1998-06-23 Heartport, Inc. System for cardiac procedures
US5263925A (en) * 1991-07-22 1993-11-23 Gilmore Jr Thomas F Photopheresis blood treatment
CA2074304C (en) * 1991-08-02 1996-11-26 Cyril J. Schweich, Jr. Drug delivery catheter
US6224619B1 (en) 1991-12-17 2001-05-01 Heartport, Inc. Blood vessel occlusion trocar having size and shape varying insertion body
US5344398A (en) * 1992-02-25 1994-09-06 Japan Crescent, Inc. Heated balloon catheter
US5578008A (en) * 1992-04-22 1996-11-26 Japan Crescent, Inc. Heated balloon catheter
US6132419A (en) * 1992-05-22 2000-10-17 Genetronics, Inc. Electroporetic gene and drug therapy
US5501662A (en) * 1992-05-22 1996-03-26 Genetronics, Inc. Implantable electroporation method and apparatus for drug and gene delivery
US5304120A (en) * 1992-07-01 1994-04-19 Btx Inc. Electroporation method and apparatus for insertion of drugs and genes into endothelial cells
US5507724A (en) * 1992-07-01 1996-04-16 Genetronics, Inc. Electroporation and iontophoresis apparatus and method for insertion of drugs and genes into cells
US5755968A (en) * 1992-07-30 1998-05-26 Stone; Andrew Dialysis system and method for removing toxic matter from the serum of the large intestine
WO1994003215A1 (en) * 1992-07-30 1994-02-17 Andrew Stone Dialysis system, method and filtrate solution composition
US5462520A (en) * 1992-08-17 1995-10-31 Genetronics, Inc. Transsurface drug delivery by electrofusion of microbubbles to the tissue surface
US5688233A (en) * 1992-08-17 1997-11-18 Genetronics, Inc. Electronincorporation enhanced transdermal delivery of molecules
US5634899A (en) * 1993-08-20 1997-06-03 Cortrak Medical, Inc. Simultaneous cardiac pacing and local drug delivery method
US5807306A (en) * 1992-11-09 1998-09-15 Cortrak Medical, Inc. Polymer matrix drug delivery apparatus
US5256141A (en) * 1992-12-22 1993-10-26 Nelson Gencheff Biological material deployment method and apparatus
US5401239A (en) * 1993-03-11 1995-03-28 Physion S.R.L. Electromotive treatment of catheter-rerelated infections
WO1994021320A1 (en) * 1993-03-15 1994-09-29 Advanced Cardiovascular Systems, Inc. Fluid delivery catheter
US5891459A (en) * 1993-06-11 1999-04-06 The Board Of Trustees Of The Leland Stanford Junior University Enhancement of vascular function by modulation of endogenous nitric oxide production or activity
US5861168A (en) * 1993-06-11 1999-01-19 The Board Of Trustees Of The Leland Stanford Junior University Intramural delivery of nitric oxide enhancer for inhibiting lesion formation after vascular injury
US5852058A (en) * 1993-06-11 1998-12-22 The Board Of Trustees Of The Leland Stanford Junior University Intramural delivery of nitric oxide enhancer for inhibiting lesion formation after vascular injury
US5344402A (en) * 1993-06-30 1994-09-06 Cardiovascular Dynamics, Inc. Low profile perfusion catheter
US5797903A (en) * 1996-04-12 1998-08-25 Ep Technologies, Inc. Tissue heating and ablation systems and methods using porous electrode structures with electrically conductive surfaces
US5421818A (en) * 1993-10-18 1995-06-06 Inner Ear Medical Delivery Systems, Inc. Multi-functional inner ear treatment and diagnostic system
US5397307A (en) * 1993-12-07 1995-03-14 Schneider (Usa) Inc. Drug delivery PTCA catheter and method for drug delivery
US5419763B1 (en) * 1994-01-04 1997-07-15 Cor Trak Medical Inc Prostatic drug-delivery catheter
JP3403233B2 (en) * 1994-01-20 2003-05-06 テルモ株式会社 Balloon catheter
US5415636A (en) * 1994-04-13 1995-05-16 Schneider (Usa) Inc Dilation-drug delivery catheter
US5486160A (en) * 1994-05-04 1996-01-23 Physion S.R.L. Device and method for the combined electropharmacological treatment of the bladder and the prostatic urethra
US5478309A (en) 1994-05-27 1995-12-26 William P. Sweezer, Jr. Catheter system and method for providing cardiopulmonary bypass pump support during heart surgery
US5505700A (en) * 1994-06-14 1996-04-09 Cordis Corporation Electro-osmotic infusion catheter
US5728068A (en) * 1994-06-14 1998-03-17 Cordis Corporation Multi-purpose balloon catheter
US5681278A (en) * 1994-06-23 1997-10-28 Cormedics Corp. Coronary vasculature treatment method
US6009877A (en) 1994-06-24 2000-01-04 Edwards; Stuart D. Method for treating a sphincter
US5575788A (en) * 1994-06-24 1996-11-19 Stuart D. Edwards Thin layer ablation apparatus
US6024743A (en) * 1994-06-24 2000-02-15 Edwards; Stuart D. Method and apparatus for selective treatment of the uterus
US5681308A (en) * 1994-06-24 1997-10-28 Stuart D. Edwards Ablation apparatus for cardiac chambers
US6405732B1 (en) 1994-06-24 2002-06-18 Curon Medical, Inc. Method to treat gastric reflux via the detection and ablation of gastro-esophageal nerves and receptors
US6056744A (en) 1994-06-24 2000-05-02 Conway Stuart Medical, Inc. Sphincter treatment apparatus
US5505730A (en) * 1994-06-24 1996-04-09 Stuart D. Edwards Thin layer ablation apparatus
US5514092A (en) * 1994-08-08 1996-05-07 Schneider (Usa) Inc. Drug delivery and dilatation-drug delivery catheters in a rapid exchange configuration
AUPM982694A0 (en) * 1994-12-02 1995-01-05 University Of Queensland, The Iontophoresis method and apparatus
US5569198A (en) * 1995-01-23 1996-10-29 Cortrak Medical Inc. Microporous catheter
US5749845A (en) * 1995-01-25 1998-05-12 Iotek, Inc. Delivering an agent to an organ
US5735817A (en) * 1995-05-19 1998-04-07 Shantha; T. R. Apparatus for transsphenoidal stimulation of the pituitary gland and adjoining brain structures
US5900433A (en) * 1995-06-23 1999-05-04 Cormedics Corp. Vascular treatment method and apparatus
US5865801A (en) * 1995-07-18 1999-02-02 Houser; Russell A. Multiple compartmented balloon catheter with external pressure sensing
US6302875B1 (en) 1996-10-11 2001-10-16 Transvascular, Inc. Catheters and related devices for forming passageways between blood vessels or other anatomical structures
DE69637676D1 (en) * 1995-11-09 2008-10-23 Univ R Use of locally administered lysines to IMPROVE VASCULAR FUNCTION
WO1997018855A1 (en) * 1995-11-21 1997-05-29 Eduard Naumovich Lerner Device for enhanced delivery of biologically active substances and compounds in an organism
US6678553B2 (en) * 1995-11-21 2004-01-13 Intraabrain International Nv Device for enhanced delivery of biologically active substances and compounds in an organism
US5779661A (en) * 1995-12-11 1998-07-14 Physion, S.R.L. Method of treating dysfunctional bladder syndromes by electromotive drug administration
EP0780139A1 (en) * 1995-12-22 1997-06-25 PHYSION S.r.l. Device for the combined electropharmacological treatment of the bladder and the prostatic urethra
IL125424A0 (en) 1998-07-20 1999-03-12 New Technologies Sa Ysy Ltd Pacing with hemodynamic enhancement
US9289618B1 (en) 1996-01-08 2016-03-22 Impulse Dynamics Nv Electrical muscle controller
AU724404B2 (en) * 1996-01-08 2000-09-21 Impulse Dynamics N.V. Electrical muscle controller
US7167748B2 (en) 1996-01-08 2007-01-23 Impulse Dynamics Nv Electrical muscle controller
US8825152B2 (en) 1996-01-08 2014-09-02 Impulse Dynamics, N.V. Modulation of intracellular calcium concentration using non-excitatory electrical signals applied to the tissue
US8321013B2 (en) 1996-01-08 2012-11-27 Impulse Dynamics, N.V. Electrical muscle controller and pacing with hemodynamic enhancement
US9713723B2 (en) 1996-01-11 2017-07-25 Impulse Dynamics Nv Signal delivery through the right ventricular septum
US5895417A (en) * 1996-03-06 1999-04-20 Cardiac Pathways Corporation Deflectable loop design for a linear lesion ablation apparatus
US6015407A (en) * 1996-03-06 2000-01-18 Cardiac Pathways Corporation Combination linear ablation and cooled tip RF catheters
US6032077A (en) * 1996-03-06 2000-02-29 Cardiac Pathways Corporation Ablation catheter with electrical coupling via foam drenched with a conductive fluid
US5800482A (en) * 1996-03-06 1998-09-01 Cardiac Pathways Corporation Apparatus and method for linear lesion ablation
WO1997041916A1 (en) * 1996-05-03 1997-11-13 Emed Corporation Combined coronary stent deployment and local delivery of an agent
US5944710A (en) * 1996-06-24 1999-08-31 Genetronics, Inc. Electroporation-mediated intravascular delivery
US5709653A (en) * 1996-07-25 1998-01-20 Cordis Corporation Photodynamic therapy balloon catheter with microporous membrane
US5797868A (en) * 1996-07-25 1998-08-25 Cordis Corporation Photodynamic therapy balloon catheter
US5720775A (en) * 1996-07-31 1998-02-24 Cordis Corporation Percutaneous atrial line ablation catheter
US7840264B1 (en) 1996-08-19 2010-11-23 Mr3 Medical, Llc System and method for breaking reentry circuits by cooling cardiac tissue
US7908003B1 (en) 1996-08-19 2011-03-15 Mr3 Medical Llc System and method for treating ischemia by improving cardiac efficiency
US6066489A (en) * 1996-08-30 2000-05-23 Arrow International, Inc. Method for treating blood borne viral pathogens such as immunodeficiency virus
US8353908B2 (en) 1996-09-20 2013-01-15 Novasys Medical, Inc. Treatment of tissue in sphincters, sinuses, and orifices
EP0835673A3 (en) * 1996-10-10 1998-09-23 Schneider (Usa) Inc. Catheter for tissue dilatation and drug delivery
US5704908A (en) * 1996-10-10 1998-01-06 Genetronics, Inc. Electroporation and iontophoresis catheter with porous balloon
US6464697B1 (en) 1998-02-19 2002-10-15 Curon Medical, Inc. Stomach and adjoining tissue regions in the esophagus
US5722403A (en) * 1996-10-28 1998-03-03 Ep Technologies, Inc. Systems and methods using a porous electrode for ablating and visualizing interior tissue regions
US6059726A (en) * 1996-11-08 2000-05-09 The Regents Of The University Of California Method for locating the atrio-ventricular (AV) junction of the heart and injecting active substances therein
US6913763B2 (en) * 1996-11-19 2005-07-05 Intrabrain International Nv Method and device for enhanced delivery of a biologically active agent through the spinal spaces into the central nervous system of a mammal
US6076012A (en) * 1996-12-19 2000-06-13 Ep Technologies, Inc. Structures for supporting porous electrode elements
US6001094A (en) * 1997-01-09 1999-12-14 Vidacare International, Inc. Implantable soluble electrode system
US5755687A (en) 1997-04-01 1998-05-26 Heartport, Inc. Methods and devices for occluding a patient's ascending aorta
US7027869B2 (en) 1998-01-07 2006-04-11 Asthmatx, Inc. Method for treating an asthma attack
US6488673B1 (en) * 1997-04-07 2002-12-03 Broncus Technologies, Inc. Method of increasing gas exchange of a lung
US7992572B2 (en) 1998-06-10 2011-08-09 Asthmatx, Inc. Methods of evaluating individuals having reversible obstructive pulmonary disease
US6634363B1 (en) 1997-04-07 2003-10-21 Broncus Technologies, Inc. Methods of treating lungs having reversible obstructive pulmonary disease
US6024740A (en) 1997-07-08 2000-02-15 The Regents Of The University Of California Circumferential ablation device assembly
US6045528A (en) * 1997-06-13 2000-04-04 Intraear, Inc. Inner ear fluid transfer and diagnostic system
BR9810372A (en) 1997-06-30 2000-09-05 Rhone Poulenc Rorer Sa Nucleic acid transfer process into cells of multicellular eukaryotic organisms in vivo, composition, nucleic acid and electric field, and, combination product
HUP0004589A3 (en) 1997-06-30 2003-08-28 Centre Nat Rech Scient Improved method for transferring nucleic acid into the striped muscle and combination therefor
US6241666B1 (en) 1997-07-03 2001-06-05 Cardiac Pathways Corp. Ablation catheter tip with a buffer layer covering the electrode
US5997532A (en) * 1997-07-03 1999-12-07 Cardiac Pathways Corporation Ablation catheter tip with a buffer layer covering the electrode
EP0996482B1 (en) 1997-07-16 2007-02-14 Metacure NV Smooth muscle controller
US6010500A (en) * 1997-07-21 2000-01-04 Cardiac Pathways Corporation Telescoping apparatus and method for linear lesion ablation
US9023031B2 (en) 1997-08-13 2015-05-05 Verathon Inc. Noninvasive devices, methods, and systems for modifying tissues
US5866561A (en) * 1997-08-21 1999-02-02 Scimed Life Systems, Inc. Local delivery of estrogen for angiogenesis
US5957901A (en) * 1997-10-14 1999-09-28 Merit Medical Systems, Inc. Catheter with improved spray pattern for pharmaco-mechanical thrombolysis therapy
US6042561A (en) * 1997-10-22 2000-03-28 Ash Medical Systems, Inc. Non-intravascular infusion access device
US7921855B2 (en) 1998-01-07 2011-04-12 Asthmatx, Inc. Method for treating an asthma attack
WO1999035988A1 (en) * 1998-01-14 1999-07-22 Conway-Stuart Medical, Inc. Electrosurgical device for sphincter treatment
AU2317899A (en) 1998-01-14 1999-08-02 Conway-Stuart Medical, Inc. Gerd treatment apparatus and method
US6440128B1 (en) 1998-01-14 2002-08-27 Curon Medical, Inc. Actively cooled electrode assemblies for forming lesions to treat dysfunction in sphincters and adjoining tissue regions
EP1047348A1 (en) 1998-01-14 2000-11-02 Conway-Stuart Medical, Inc. Lectrosurgical apparatus for treating gatroesophageal reflux disease (gerd) and method
US6159178A (en) * 1998-01-23 2000-12-12 Heartport, Inc. Methods and devices for occluding the ascending aorta and maintaining circulation of oxygenated blood in the patient when the patient's heart is arrested
DE69923291T2 (en) 1998-02-19 2005-06-09 Curon Medical Inc., Sunnyvale ELECTRO-SURGERY DEVICE FOR THE TREATMENT OF CLOSURE MUSCLES
US6258087B1 (en) 1998-02-19 2001-07-10 Curon Medical, Inc. Expandable electrode assemblies for forming lesions to treat dysfunction in sphincters and adjoining tissue regions
US8906010B2 (en) * 1998-02-19 2014-12-09 Mederi Therapeutics, Inc. Graphical user interface for association with an electrode structure deployed in contact with a tissue region
US6423058B1 (en) 1998-02-19 2002-07-23 Curon Medical, Inc. Assemblies to visualize and treat sphincters and adjoining tissue regions
US6325798B1 (en) 1998-02-19 2001-12-04 Curon Medical, Inc. Vacuum-assisted systems and methods for treating sphincters and adjoining tissue regions
US6355031B1 (en) 1998-02-19 2002-03-12 Curon Medical, Inc. Control systems for multiple electrode arrays to create lesions in tissue regions at or near a sphincter
US6273886B1 (en) 1998-02-19 2001-08-14 Curon Medical, Inc. Integrated tissue heating and cooling apparatus
US7165551B2 (en) 1998-02-19 2007-01-23 Curon Medical, Inc. Apparatus to detect and treat aberrant myoelectric activity
US6790207B2 (en) 1998-06-04 2004-09-14 Curon Medical, Inc. Systems and methods for applying a selected treatment agent into contact with tissue to treat disorders of the gastrointestinal tract
US6402744B2 (en) 1998-02-19 2002-06-11 Curon Medical, Inc. Systems and methods for forming composite lesions to treat dysfunction in sphincters and adjoining tissue regions
US6358245B1 (en) 1998-02-19 2002-03-19 Curon Medical, Inc. Graphical user interface for association with an electrode structure deployed in contact with a tissue region
US20030135206A1 (en) 1998-02-27 2003-07-17 Curon Medical, Inc. Method for treating a sphincter
JP2002504390A (en) 1998-02-27 2002-02-12 キューロン メディカル,インコーポレイテッド Apparatus for electrosurgically treating esophageal sphincter
US7713297B2 (en) 1998-04-11 2010-05-11 Boston Scientific Scimed, Inc. Drug-releasing stent with ceramic-containing layer
US6219577B1 (en) 1998-04-14 2001-04-17 Global Vascular Concepts, Inc. Iontophoresis, electroporation and combination catheters for local drug delivery to arteries and other body tissues
AU3672299A (en) 1998-04-30 1999-11-16 Stuart D Edwards Electrosurgical sphincter treatment apparatus
US6267747B1 (en) 1998-05-11 2001-07-31 Cardeon Corporation Aortic catheter with porous aortic root balloon and methods for inducing cardioplegic arrest
US6802841B2 (en) 1998-06-04 2004-10-12 Curon Medical, Inc. Systems and methods for applying a selected treatment agent into contact with tissue to treat sphincter dysfunction
US7198635B2 (en) 2000-10-17 2007-04-03 Asthmatx, Inc. Modification of airways by application of energy
US8181656B2 (en) 1998-06-10 2012-05-22 Asthmatx, Inc. Methods for treating airways
US6440102B1 (en) 1998-07-23 2002-08-27 Durect Corporation Fluid transfer and diagnostic system for treating the inner ear
US8197461B1 (en) 1998-12-04 2012-06-12 Durect Corporation Controlled release system for delivering therapeutic agents into the inner ear
US6406455B1 (en) * 1998-12-18 2002-06-18 Biovalve Technologies, Inc. Injection devices
US6955661B1 (en) 1999-01-25 2005-10-18 Atrium Medical Corporation Expandable fluoropolymer device for delivery of therapeutic agents and method of making
ES2338405T3 (en) 1999-02-04 2010-05-07 Pluristem Ltd. METHOD AND APPARATUS FOR MAINTENANCE AND EXPASION OF HEMOPOYTIC MOTHER CELLS AND / OR PROGENITOR CELLS.
IL144948A0 (en) 1999-02-18 2002-06-30 Biovalve Technologies Inc Electroactive pore
US9101765B2 (en) 1999-03-05 2015-08-11 Metacure Limited Non-immediate effects of therapy
US8019421B2 (en) 1999-03-05 2011-09-13 Metacure Limited Blood glucose level control
US8666495B2 (en) 1999-03-05 2014-03-04 Metacure Limited Gastrointestinal methods and apparatus for use in treating disorders and controlling blood sugar
US8346363B2 (en) 1999-03-05 2013-01-01 Metacure Limited Blood glucose level control
US8700161B2 (en) 1999-03-05 2014-04-15 Metacure Limited Blood glucose level control
US6792306B2 (en) * 2000-03-10 2004-09-14 Biophoretic Therapeutic Systems, Llc Finger-mounted electrokinetic delivery system for self-administration of medicaments and methods therefor
DE19912844A1 (en) * 1999-03-22 2000-09-28 Saphir Medical Products Gmbh Use of a cutting device, which uses a fluid as cutting medium, for surgical treatment
US6047209A (en) * 1999-04-02 2000-04-04 Denny; Jeffrey Paul Method and apparatus for maintenance of pierced orifices
US6425877B1 (en) * 1999-04-02 2002-07-30 Novasys Medical, Inc. Treatment of tissue in the digestive circulatory respiratory urinary and reproductive systems
US6593130B1 (en) 1999-04-16 2003-07-15 The Regents Of The University Of California Method and apparatus for ex vivo and in vivo cellular electroporation of gene protein or drug therapy
WO2000066017A1 (en) 1999-05-04 2000-11-09 Curon Medical, Inc. Electrodes for creating lesions in tissue regions at or near a sphincter
US7190997B1 (en) 1999-06-04 2007-03-13 Impulse Dynamics Nv Drug delivery device
US7171263B2 (en) * 1999-06-04 2007-01-30 Impulse Dynamics Nv Drug delivery device
US7092753B2 (en) * 1999-06-04 2006-08-15 Impulse Dynamics Nv Drug delivery device
AU4947100A (en) * 1999-06-04 2000-12-28 Impulse Dynamics N.V. Drug delivery device
IL141250A0 (en) * 1999-06-05 2002-03-10 Univ Leland Stanford Junior Method and composition for inhibiting cardiovascular cell proliferation
WO2001017452A1 (en) * 1999-09-08 2001-03-15 Curon Medical, Inc. System for controlling a family of treatment devices
WO2001017453A2 (en) 1999-09-08 2001-03-15 Curon Medical, Inc. Systems and methods for monitoring and controlling use of medical devices
CA2384273A1 (en) 1999-09-08 2001-03-15 Curon Medical, Inc. Systems and methods for monitoring and controlling use of medical devices
US7048717B1 (en) 1999-09-27 2006-05-23 Essex Technology, Inc. Rotate-to-advance catheterization system
US6587718B2 (en) * 1999-10-08 2003-07-01 Scimed Life Systems, Inc. Iontophoretic delivery to heart tissue
WO2001030445A1 (en) 1999-10-25 2001-05-03 Impulse Dynamics N.V. Cardiac contractility modulation device having anti-arrhythmic capabilities and a method of operating thereof
US6993385B1 (en) 1999-10-25 2006-01-31 Impulse Dynamics N.V. Cardiac contractility modulation device having anti-arrhythmic capabilities and a method of operating thereof
US7027863B1 (en) 1999-10-25 2006-04-11 Impulse Dynamics N.V. Device for cardiac therapy
US20040215235A1 (en) 1999-11-16 2004-10-28 Barrx, Inc. Methods and systems for determining physiologic characteristics for treatment of the esophagus
WO2001035846A1 (en) 1999-11-16 2001-05-25 Ganz Robert A System and method of treating abnormal tissue in the human esophagus
US20060095032A1 (en) 1999-11-16 2006-05-04 Jerome Jackson Methods and systems for determining physiologic characteristics for treatment of the esophagus
US6547776B1 (en) 2000-01-03 2003-04-15 Curon Medical, Inc. Systems and methods for treating tissue in the crura
US7184827B1 (en) 2000-01-24 2007-02-27 Stuart D. Edwards Shrinkage of dilatations in the body
US8251070B2 (en) 2000-03-27 2012-08-28 Asthmatx, Inc. Methods for treating airways
US8845632B2 (en) 2000-05-18 2014-09-30 Mederi Therapeutics, Inc. Graphical user interface for monitoring and controlling use of medical devices
US7306591B2 (en) 2000-10-02 2007-12-11 Novasys Medical, Inc. Apparatus and methods for treating female urinary incontinence
US6640120B1 (en) 2000-10-05 2003-10-28 Scimed Life Systems, Inc. Probe assembly for mapping and ablating pulmonary vein tissue and method of using same
US7104987B2 (en) 2000-10-17 2006-09-12 Asthmatx, Inc. Control system and process for application of energy to airway walls and other mediums
DE10129285C2 (en) * 2001-06-18 2003-01-09 Hans-Joachim Mueschenborn Encryption procedure with arbitrary selectable one-time keys
AU2002345328A1 (en) 2001-06-27 2003-03-03 Remon Medical Technologies Ltd. Method and device for electrochemical formation of therapeutic species in vivo
FR2830767B1 (en) * 2001-10-12 2004-03-12 Optis France Sa DEVICE FOR DELIVERING DRUGS BY IONTOPHORESIS OR INTROCULAR ELECTROPORATION
US7488313B2 (en) * 2001-11-29 2009-02-10 Boston Scientific Scimed, Inc. Mechanical apparatus and method for dilating and delivering a therapeutic agent to a site of treatment
US20040219660A1 (en) * 2001-12-14 2004-11-04 Dev Sukhendu B. Electroporation-mediated intravascular delivery
DE10205373B4 (en) * 2002-02-09 2007-07-19 Aloys Wobben Fire protection
US20080213331A1 (en) 2002-04-08 2008-09-04 Ardian, Inc. Methods and devices for renal nerve blocking
US7617005B2 (en) 2002-04-08 2009-11-10 Ardian, Inc. Methods and apparatus for thermally-induced renal neuromodulation
US20070135875A1 (en) 2002-04-08 2007-06-14 Ardian, Inc. Methods and apparatus for thermally-induced renal neuromodulation
US9636174B2 (en) 2002-04-08 2017-05-02 Medtronic Ardian Luxembourg S.A.R.L. Methods for therapeutic renal neuromodulation
US8347891B2 (en) 2002-04-08 2013-01-08 Medtronic Ardian Luxembourg S.A.R.L. Methods and apparatus for performing a non-continuous circumferential treatment of a body lumen
US8150519B2 (en) 2002-04-08 2012-04-03 Ardian, Inc. Methods and apparatus for bilateral renal neuromodulation
US7756583B2 (en) 2002-04-08 2010-07-13 Ardian, Inc. Methods and apparatus for intravascularly-induced neuromodulation
US20070129761A1 (en) 2002-04-08 2007-06-07 Ardian, Inc. Methods for treating heart arrhythmia
US7048714B2 (en) * 2002-10-30 2006-05-23 Biorest Ltd. Drug eluting medical device with an expandable portion for drug release
CN101261561A (en) 2003-02-10 2008-09-10 N-特莱格有限公司 Touch detection for a digitizer
JP2006519663A (en) 2003-03-10 2006-08-31 インパルス ダイナミックス エヌヴイ Apparatus and method for delivering electrical signals for regulating gene expression in heart tissue
US9931503B2 (en) 2003-03-10 2018-04-03 Impulse Dynamics Nv Protein activity modification
US11439815B2 (en) 2003-03-10 2022-09-13 Impulse Dynamics Nv Protein activity modification
US20040226556A1 (en) 2003-05-13 2004-11-18 Deem Mark E. Apparatus for treating asthma using neurotoxin
US20040236308A1 (en) * 2003-05-22 2004-11-25 Atrium Medical Corp. Kinetic isolation pressurization
US8792985B2 (en) 2003-07-21 2014-07-29 Metacure Limited Gastrointestinal methods and apparatus for use in treating disorders and controlling blood sugar
EP2452648B1 (en) * 2003-09-12 2016-02-10 Vessix Vascular, Inc. System for selectable eccentric remodeling and/or ablation of atherosclerotic material
US7736362B2 (en) * 2003-09-15 2010-06-15 Boston Scientific Scimed, Inc. Catheter balloons
US7150745B2 (en) 2004-01-09 2006-12-19 Barrx Medical, Inc. Devices and methods for treatment of luminal tissue
US7922740B2 (en) 2004-02-24 2011-04-12 Boston Scientific Scimed, Inc. Rotatable catheter assembly
US7744619B2 (en) 2004-02-24 2010-06-29 Boston Scientific Scimed, Inc. Rotatable catheter assembly
WO2005084301A2 (en) * 2004-03-01 2005-09-15 Lumen Therapeutics, Llc Compositions and methods for treating diseases
US11779768B2 (en) 2004-03-10 2023-10-10 Impulse Dynamics Nv Protein activity modification
US8352031B2 (en) 2004-03-10 2013-01-08 Impulse Dynamics Nv Protein activity modification
US20050209548A1 (en) * 2004-03-19 2005-09-22 Dev Sukhendu B Electroporation-mediated intravascular delivery
US8092549B2 (en) 2004-09-24 2012-01-10 The Invention Science Fund I, Llc Ciliated stent-like-system
US8019413B2 (en) 2007-03-19 2011-09-13 The Invention Science Fund I, Llc Lumen-traveling biological interface device and method of use
US9801527B2 (en) 2004-04-19 2017-10-31 Gearbox, Llc Lumen-traveling biological interface device
US8337482B2 (en) 2004-04-19 2012-12-25 The Invention Science Fund I, Llc System for perfusion management
US9011329B2 (en) 2004-04-19 2015-04-21 Searete Llc Lumenally-active device
US7857767B2 (en) 2004-04-19 2010-12-28 Invention Science Fund I, Llc Lumen-traveling device
US8361013B2 (en) * 2004-04-19 2013-01-29 The Invention Science Fund I, Llc Telescoping perfusion management system
US8353896B2 (en) 2004-04-19 2013-01-15 The Invention Science Fund I, Llc Controllable release nasal system
US7850676B2 (en) 2004-04-19 2010-12-14 The Invention Science Fund I, Llc System with a reservoir for perfusion management
US7998060B2 (en) 2004-04-19 2011-08-16 The Invention Science Fund I, Llc Lumen-traveling delivery device
US7706873B2 (en) * 2004-05-05 2010-04-27 Mario Ammirati System and method for controlled delivery of a therapeutic agent to a target location within an internal body tissue
US9713730B2 (en) 2004-09-10 2017-07-25 Boston Scientific Scimed, Inc. Apparatus and method for treatment of in-stent restenosis
US8396548B2 (en) 2008-11-14 2013-03-12 Vessix Vascular, Inc. Selective drug delivery in a lumen
US20060085058A1 (en) * 2004-10-20 2006-04-20 Rosenthal Arthur L System and method for delivering a biologically active material to a body lumen
WO2006052940A2 (en) * 2004-11-05 2006-05-18 Asthmatx, Inc. Medical device with procedure improvement features
US7949407B2 (en) 2004-11-05 2011-05-24 Asthmatx, Inc. Energy delivery devices and methods
US20070093802A1 (en) 2005-10-21 2007-04-26 Danek Christopher J Energy delivery devices and methods
WO2006063199A2 (en) 2004-12-09 2006-06-15 The Foundry, Inc. Aortic valve repair
US9510732B2 (en) 2005-10-25 2016-12-06 Intuitive Surgical Operations, Inc. Methods and apparatus for efficient purging
US7860556B2 (en) 2005-02-02 2010-12-28 Voyage Medical, Inc. Tissue imaging and extraction systems
US8078266B2 (en) 2005-10-25 2011-12-13 Voyage Medical, Inc. Flow reduction hood systems
US7918787B2 (en) 2005-02-02 2011-04-05 Voyage Medical, Inc. Tissue visualization and manipulation systems
US11478152B2 (en) 2005-02-02 2022-10-25 Intuitive Surgical Operations, Inc. Electrophysiology mapping and visualization system
US8137333B2 (en) 2005-10-25 2012-03-20 Voyage Medical, Inc. Delivery of biological compounds to ischemic and/or infarcted tissue
US7860555B2 (en) 2005-02-02 2010-12-28 Voyage Medical, Inc. Tissue visualization and manipulation system
US20080015569A1 (en) 2005-02-02 2008-01-17 Voyage Medical, Inc. Methods and apparatus for treatment of atrial fibrillation
US10064540B2 (en) 2005-02-02 2018-09-04 Intuitive Surgical Operations, Inc. Visualization apparatus for transseptal access
US7930016B1 (en) 2005-02-02 2011-04-19 Voyage Medical, Inc. Tissue closure system
US8050746B2 (en) 2005-02-02 2011-11-01 Voyage Medical, Inc. Tissue visualization device and method variations
US9821158B2 (en) 2005-02-17 2017-11-21 Metacure Limited Non-immediate effects of therapy
US8244371B2 (en) 2005-03-18 2012-08-14 Metacure Limited Pancreas lead
EP1898991B1 (en) 2005-05-04 2016-06-29 Impulse Dynamics NV Protein activity modification
SE0501077L (en) * 2005-05-12 2006-11-13 Spectracure Ab Device for photodynamic diagnosis or treatment
AU2006255043B2 (en) * 2005-06-07 2013-01-17 David R. Staskin Injection guidance system and method
JP2007000342A (en) * 2005-06-23 2007-01-11 Transcutaneous Technologies Inc Iontophoresis device for controlling quantity and time of dosing a plurality of medicaments
US8295922B2 (en) 2005-08-08 2012-10-23 Tti Ellebeau, Inc. Iontophoresis device
US8386030B2 (en) 2005-08-08 2013-02-26 Tti Ellebeau, Inc. Iontophoresis device
US20070088332A1 (en) * 2005-08-22 2007-04-19 Transcutaneous Technologies Inc. Iontophoresis device
US20090254018A1 (en) * 2005-08-24 2009-10-08 Mizuo Nakayama Electrode assembly for freezing-type iontophoresis device
WO2007026672A1 (en) * 2005-08-29 2007-03-08 Transcu Ltd. General-purpose electrolyte composition for iontophoresis
WO2007029611A1 (en) * 2005-09-06 2007-03-15 Tti Ellebeau, Inc. Iontophoresis device
US20070112294A1 (en) * 2005-09-14 2007-05-17 Transcutaneous Technologies Inc. Iontophoresis device
WO2007032446A1 (en) 2005-09-15 2007-03-22 Tti Ellebeau, Inc. Rod type iontophoresis device
US20070093789A1 (en) * 2005-09-30 2007-04-26 Transcutaneous Technologies Inc. Iontophoresis apparatus and method for delivery of angiogenic factors to enhance healing of injured tissue
WO2007041115A1 (en) * 2005-09-30 2007-04-12 Tti Ellebeau Inc. Method and system to detect malfunctions in an iontophoresis device that delivers active agents to biological interfaces
WO2007037476A1 (en) * 2005-09-30 2007-04-05 Tti Ellebeau, Inc. Iontophoresis apparatus capable of controlling dose and timing of administration of sleep inducer and analeptic agent
JP2009509677A (en) * 2005-09-30 2009-03-12 Tti・エルビュー株式会社 Iontophoretic delivery of vesicle encapsulated active substances
US8221310B2 (en) 2005-10-25 2012-07-17 Voyage Medical, Inc. Tissue visualization device and method variations
US7959627B2 (en) 2005-11-23 2011-06-14 Barrx Medical, Inc. Precision ablating device
US7997278B2 (en) 2005-11-23 2011-08-16 Barrx Medical, Inc. Precision ablating method
US8702694B2 (en) 2005-11-23 2014-04-22 Covidien Lp Auto-aligning ablating device and method of use
US8840660B2 (en) 2006-01-05 2014-09-23 Boston Scientific Scimed, Inc. Bioerodible endoprostheses and methods of making the same
US8089029B2 (en) 2006-02-01 2012-01-03 Boston Scientific Scimed, Inc. Bioabsorbable metal medical device and method of manufacture
US20070224235A1 (en) 2006-03-24 2007-09-27 Barron Tenney Medical devices having nanoporous coatings for controlled therapeutic agent delivery
US8888684B2 (en) * 2006-03-27 2014-11-18 Boston Scientific Scimed, Inc. Medical devices with local drug delivery capabilities
US8187620B2 (en) 2006-03-27 2012-05-29 Boston Scientific Scimed, Inc. Medical devices comprising a porous metal oxide or metal material and a polymer coating for delivering therapeutic agents
US20120035438A1 (en) 2006-04-12 2012-02-09 Searete Llc, A Limited Liability Corporation Of The State Of Delaware Path selection by a lumen traveling device in a body tub tree based on previous path
US8048150B2 (en) 2006-04-12 2011-11-01 Boston Scientific Scimed, Inc. Endoprosthesis having a fiber meshwork disposed thereon
US8019435B2 (en) 2006-05-02 2011-09-13 Boston Scientific Scimed, Inc. Control of arterial smooth muscle tone
US9055906B2 (en) 2006-06-14 2015-06-16 Intuitive Surgical Operations, Inc. In-vivo visualization systems
US8815275B2 (en) 2006-06-28 2014-08-26 Boston Scientific Scimed, Inc. Coatings for medical devices comprising a therapeutic agent and a metallic material
JP2009542359A (en) 2006-06-29 2009-12-03 ボストン サイエンティフィック リミテッド Medical device with selective covering
EP2386322B1 (en) * 2006-07-03 2017-12-27 Hemoteq AG Production, method and use of medical products which release agents for opening blood vessels on a permanent basis
JP2009545407A (en) 2006-08-02 2009-12-24 ボストン サイエンティフィック サイムド,インコーポレイテッド End prosthesis with 3D decomposition control
US10004388B2 (en) 2006-09-01 2018-06-26 Intuitive Surgical Operations, Inc. Coronary sinus cannulation
WO2008028149A2 (en) 2006-09-01 2008-03-06 Voyage Medical, Inc. Electrophysiology mapping and visualization system
US20080097476A1 (en) 2006-09-01 2008-04-24 Voyage Medical, Inc. Precision control systems for tissue visualization and manipulation assemblies
US8260411B1 (en) * 2006-09-06 2012-09-04 Twin Star Medical, Inc. Conductive injection and aspiration device and method
JP2010503469A (en) 2006-09-14 2010-02-04 ボストン サイエンティフィック リミテッド Medical device having drug-eluting film
EP2068782B1 (en) 2006-09-15 2011-07-27 Boston Scientific Limited Bioerodible endoprostheses
US8808726B2 (en) 2006-09-15 2014-08-19 Boston Scientific Scimed. Inc. Bioerodible endoprostheses and methods of making the same
US8128689B2 (en) 2006-09-15 2012-03-06 Boston Scientific Scimed, Inc. Bioerodible endoprosthesis with biostable inorganic layers
WO2008034013A2 (en) 2006-09-15 2008-03-20 Boston Scientific Limited Medical devices and methods of making the same
JP2010503482A (en) 2006-09-18 2010-02-04 ボストン サイエンティフィック リミテッド Endoprosthesis
CA2666661C (en) 2006-10-18 2015-01-20 Minnow Medical, Inc. Tuned rf energy and electrical tissue characterization for selective treatment of target tissues
WO2008049082A2 (en) 2006-10-18 2008-04-24 Minnow Medical, Inc. Inducing desirable temperature effects on body tissue
WO2008049087A2 (en) 2006-10-18 2008-04-24 Minnow Medical, Inc. System for inducing desirable temperature effects on body tissue
US7931647B2 (en) 2006-10-20 2011-04-26 Asthmatx, Inc. Method of delivering energy to a lung airway using markers
US10335131B2 (en) 2006-10-23 2019-07-02 Intuitive Surgical Operations, Inc. Methods for preventing tissue migration
US7981150B2 (en) 2006-11-09 2011-07-19 Boston Scientific Scimed, Inc. Endoprosthesis with coatings
JP5383497B2 (en) 2006-12-01 2014-01-08 Tti・エルビュー株式会社 System and device for powering and / or controlling a device, for example a transdermal delivery device
US20080183036A1 (en) 2006-12-18 2008-07-31 Voyage Medical, Inc. Systems and methods for unobstructed visualization and ablation
US8758229B2 (en) 2006-12-21 2014-06-24 Intuitive Surgical Operations, Inc. Axial visualization systems
US8131350B2 (en) 2006-12-21 2012-03-06 Voyage Medical, Inc. Stabilization of visualization catheters
WO2008083190A2 (en) 2006-12-28 2008-07-10 Boston Scientific Limited Bioerodible endoprostheses and methods of making same
DE112008000881A5 (en) 2007-01-21 2010-01-21 Hemoteq Ag Medical device for the treatment of occlusions of body passages and for the prevention of imminent reocclusions
US8070797B2 (en) 2007-03-01 2011-12-06 Boston Scientific Scimed, Inc. Medical device with a porous surface for delivery of a therapeutic agent
US8431149B2 (en) 2007-03-01 2013-04-30 Boston Scientific Scimed, Inc. Coated medical devices for abluminal drug delivery
US8067054B2 (en) 2007-04-05 2011-11-29 Boston Scientific Scimed, Inc. Stents with ceramic drug reservoir layer and methods of making and using the same
US8496653B2 (en) 2007-04-23 2013-07-30 Boston Scientific Scimed, Inc. Thrombus removal
US9155452B2 (en) 2007-04-27 2015-10-13 Intuitive Surgical Operations, Inc. Complex shape steerable tissue visualization and manipulation catheter
WO2008137757A1 (en) 2007-05-04 2008-11-13 Barrx Medical, Inc. Method and apparatus for gastrointestinal tract ablation for treatment of obesity
US8657805B2 (en) 2007-05-08 2014-02-25 Intuitive Surgical Operations, Inc. Complex shape steerable tissue visualization and manipulation catheter
US8709008B2 (en) 2007-05-11 2014-04-29 Intuitive Surgical Operations, Inc. Visual electrode ablation systems
US20120149985A1 (en) * 2007-05-18 2012-06-14 Frassica James J Rotate-to-advance catheterization system
US7976915B2 (en) 2007-05-23 2011-07-12 Boston Scientific Scimed, Inc. Endoprosthesis with select ceramic morphology
US8784338B2 (en) 2007-06-22 2014-07-22 Covidien Lp Electrical means to normalize ablational energy transmission to a luminal tissue surface of varying size
US9192697B2 (en) 2007-07-03 2015-11-24 Hemoteq Ag Balloon catheter for treating stenosis of body passages and for preventing threatening restenosis
EP2173412A4 (en) * 2007-07-06 2011-07-27 Allievion Medical Inc Constrained fluid delivery device
US8251992B2 (en) 2007-07-06 2012-08-28 Tyco Healthcare Group Lp Method and apparatus for gastrointestinal tract ablation to achieve loss of persistent and/or recurrent excess body weight following a weight-loss operation
KR101547931B1 (en) 2007-07-06 2015-08-28 코비디엔 엘피 Ablation in the gastrointestinal tract to achieve hemostasis and eradicate lesions with a propensity for bleeding
US8002823B2 (en) 2007-07-11 2011-08-23 Boston Scientific Scimed, Inc. Endoprosthesis coating
US7942926B2 (en) 2007-07-11 2011-05-17 Boston Scientific Scimed, Inc. Endoprosthesis coating
US8235983B2 (en) 2007-07-12 2012-08-07 Asthmatx, Inc. Systems and methods for delivering energy to passageways in a patient
JP2010533563A (en) 2007-07-19 2010-10-28 ボストン サイエンティフィック リミテッド Endoprosthesis with adsorption inhibiting surface
US7931683B2 (en) 2007-07-27 2011-04-26 Boston Scientific Scimed, Inc. Articles having ceramic coated surfaces
US8815273B2 (en) 2007-07-27 2014-08-26 Boston Scientific Scimed, Inc. Drug eluting medical devices having porous layers
US8273012B2 (en) 2007-07-30 2012-09-25 Tyco Healthcare Group, Lp Cleaning device and methods
US8646460B2 (en) 2007-07-30 2014-02-11 Covidien Lp Cleaning device and methods
WO2009018340A2 (en) 2007-07-31 2009-02-05 Boston Scientific Scimed, Inc. Medical device coating by laser cladding
JP2010535541A (en) 2007-08-03 2010-11-25 ボストン サイエンティフィック リミテッド Coating for medical devices with large surface area
US8235985B2 (en) 2007-08-31 2012-08-07 Voyage Medical, Inc. Visualization and ablation system variations
US20110137245A1 (en) * 2007-09-12 2011-06-09 Cook Medical Technologies Llc Balloon catheter with embedded rod
WO2009036135A1 (en) 2007-09-12 2009-03-19 Cook Incorporated Balloon catheter for delivering a therapeutic agent
US8052745B2 (en) 2007-09-13 2011-11-08 Boston Scientific Scimed, Inc. Endoprosthesis
US8029554B2 (en) 2007-11-02 2011-10-04 Boston Scientific Scimed, Inc. Stent with embedded material
US7938855B2 (en) 2007-11-02 2011-05-10 Boston Scientific Scimed, Inc. Deformable underlayer for stent
US8216632B2 (en) 2007-11-02 2012-07-10 Boston Scientific Scimed, Inc. Endoprosthesis coating
US8858609B2 (en) 2008-02-07 2014-10-14 Intuitive Surgical Operations, Inc. Stent delivery under direct visualization
US8483831B1 (en) 2008-02-15 2013-07-09 Holaira, Inc. System and method for bronchial dilation
CA2752444A1 (en) * 2008-02-25 2009-09-03 The University Of North Carolina At Chapel Hill Delivery apparatus and associated method
US8034022B2 (en) 2008-04-08 2011-10-11 Cook Medical Technologies Llc Weeping balloon catheter
WO2009131911A2 (en) 2008-04-22 2009-10-29 Boston Scientific Scimed, Inc. Medical devices having a coating of inorganic material
WO2009132176A2 (en) 2008-04-24 2009-10-29 Boston Scientific Scimed, Inc. Medical devices having inorganic particle layers
US7998192B2 (en) 2008-05-09 2011-08-16 Boston Scientific Scimed, Inc. Endoprostheses
CA2723806C (en) 2008-05-09 2022-05-31 Innovative Pulmonary Solutions, Inc. Systems, assemblies, and methods for treating a bronchial tree
US7873404B1 (en) 2008-05-29 2011-01-18 Seth Caplan Method for performing angioplasty and angiography with a single catheter
US8236046B2 (en) 2008-06-10 2012-08-07 Boston Scientific Scimed, Inc. Bioerodible endoprosthesis
EP2303350A2 (en) 2008-06-18 2011-04-06 Boston Scientific Scimed, Inc. Endoprosthesis coating
US9101735B2 (en) 2008-07-07 2015-08-11 Intuitive Surgical Operations, Inc. Catheter control systems
CA2731139A1 (en) * 2008-07-18 2010-01-21 Suntek Medical Scientific And Technologies (Shanghai) Co., Ltd. An apparatus of low strength electric field network-mediated delivery of drug to target cell of liver
US7985252B2 (en) 2008-07-30 2011-07-26 Boston Scientific Scimed, Inc. Bioerodible endoprosthesis
US8840602B2 (en) * 2008-07-31 2014-09-23 Acclarent, Inc. Systems and methods for anesthetizing ear tissue
US8133199B2 (en) 2008-08-27 2012-03-13 Boston Scientific Scimed, Inc. Electroactive polymer activation system for a medical device
US8382824B2 (en) 2008-10-03 2013-02-26 Boston Scientific Scimed, Inc. Medical implant having NANO-crystal grains with barrier layers of metal nitrides or fluorides
US8894643B2 (en) 2008-10-10 2014-11-25 Intuitive Surgical Operations, Inc. Integral electrode placement and connection systems
US8333012B2 (en) 2008-10-10 2012-12-18 Voyage Medical, Inc. Method of forming electrode placement and connection systems
US9468364B2 (en) 2008-11-14 2016-10-18 Intuitive Surgical Operations, Inc. Intravascular catheter with hood and image processing systems
WO2010056745A1 (en) 2008-11-17 2010-05-20 Minnow Medical, Inc. Selective accumulation of energy with or without knowledge of tissue topography
US8231980B2 (en) 2008-12-03 2012-07-31 Boston Scientific Scimed, Inc. Medical implants including iridium oxide
US8923970B2 (en) 2008-12-09 2014-12-30 Nephera Ltd. Stimulation of the urinary system
US8725249B2 (en) 2008-12-09 2014-05-13 Nephera Ltd. Stimulation of the urinary system
US20100160906A1 (en) * 2008-12-23 2010-06-24 Asthmatx, Inc. Expandable energy delivery devices having flexible conductive elements and associated systems and methods
KR101674904B1 (en) 2009-02-26 2016-11-10 더 유니버시티 오브 노쓰 캐롤라이나 엣 채플 힐 Interventional drug delivery system and associated methods
US8267992B2 (en) 2009-03-02 2012-09-18 Boston Scientific Scimed, Inc. Self-buffering medical implants
US8071156B2 (en) 2009-03-04 2011-12-06 Boston Scientific Scimed, Inc. Endoprostheses
US8287937B2 (en) 2009-04-24 2012-10-16 Boston Scientific Scimed, Inc. Endoprosthese
EP2421571A2 (en) * 2009-04-24 2012-02-29 Boston Scientific Scimed, Inc. Use of drug polymorphs to achieve controlled drug delivery from a coated medical device
US8551096B2 (en) * 2009-05-13 2013-10-08 Boston Scientific Scimed, Inc. Directional delivery of energy and bioactives
EP2440694A4 (en) * 2009-06-09 2012-12-19 Tti Ellebeau Inc Long life high capacity electrode, device, and method of manufacture
ES2550634T3 (en) * 2009-07-10 2015-11-11 Boston Scientific Scimed, Inc. Use of nanocrystals for a drug delivery balloon
US10080821B2 (en) 2009-07-17 2018-09-25 Boston Scientific Scimed, Inc. Nucleation of drug delivery balloons to provide improved crystal size and density
US10265435B2 (en) 2009-08-27 2019-04-23 Silver Bullet Therapeutics, Inc. Bone implant and systems and coatings for the controllable release of antimicrobial metal ions
US9821094B2 (en) 2014-06-11 2017-11-21 Silver Bullet Therapeutics, Inc. Coatings for the controllable release of antimicrobial metal ions
US8927004B1 (en) 2014-06-11 2015-01-06 Silver Bullet Therapeutics, Inc. Bioabsorbable substrates and systems that controllably release antimicrobial metal ions
EP2470257B1 (en) 2009-08-27 2015-03-04 Silver Bullet Therapeutics Inc. Bone implants for the treatment of infection
US9114197B1 (en) 2014-06-11 2015-08-25 Silver Bullett Therapeutics, Inc. Coatings for the controllable release of antimicrobial metal ions
US9474565B2 (en) 2009-09-22 2016-10-25 Mederi Therapeutics, Inc. Systems and methods for treating tissue with radiofrequency energy
US9750563B2 (en) 2009-09-22 2017-09-05 Mederi Therapeutics, Inc. Systems and methods for treating tissue with radiofrequency energy
US20110112529A1 (en) 2009-09-22 2011-05-12 Mederi Therapeutics Inc. Systems and methods for controlling use and operation of a family of different treatment devices
US9775664B2 (en) 2009-09-22 2017-10-03 Mederi Therapeutics, Inc. Systems and methods for treating tissue with radiofrequency energy
US10386990B2 (en) 2009-09-22 2019-08-20 Mederi Rf, Llc Systems and methods for treating tissue with radiofrequency energy
JP5843777B2 (en) 2009-10-27 2016-01-13 ホライラ, インコーポレイテッド Delivery device having a coolable energy release assembly
US8911439B2 (en) 2009-11-11 2014-12-16 Holaira, Inc. Non-invasive and minimally invasive denervation methods and systems for performing the same
AU2010319477A1 (en) 2009-11-11 2012-05-24 Holaira, Inc. Systems, apparatuses, and methods for treating tissue and controlling stenosis
US8934975B2 (en) 2010-02-01 2015-01-13 Metacure Limited Gastrointestinal electrical therapy
US8694071B2 (en) 2010-02-12 2014-04-08 Intuitive Surgical Operations, Inc. Image stabilization techniques and methods
WO2011119573A1 (en) 2010-03-23 2011-09-29 Boston Scientific Scimed, Inc. Surface treated bioerodible metal endoprostheses
US9814522B2 (en) 2010-04-06 2017-11-14 Intuitive Surgical Operations, Inc. Apparatus and methods for ablation efficacy
JP2013523318A (en) 2010-04-09 2013-06-17 べシックス・バスキュラー・インコーポレイテッド Power generation and control equipment for tissue treatment
US9192790B2 (en) 2010-04-14 2015-11-24 Boston Scientific Scimed, Inc. Focused ultrasonic renal denervation
US9265913B2 (en) 2010-09-22 2016-02-23 Vital 5, Llc Catheter assembly
US8473067B2 (en) 2010-06-11 2013-06-25 Boston Scientific Scimed, Inc. Renal denervation and stimulation employing wireless vascular energy transfer arrangement
US9155589B2 (en) 2010-07-30 2015-10-13 Boston Scientific Scimed, Inc. Sequential activation RF electrode set for renal nerve ablation
US9408661B2 (en) 2010-07-30 2016-08-09 Patrick A. Haverkost RF electrodes on multiple flexible wires for renal nerve ablation
US9358365B2 (en) 2010-07-30 2016-06-07 Boston Scientific Scimed, Inc. Precision electrode movement control for renal nerve ablation
US9463062B2 (en) 2010-07-30 2016-10-11 Boston Scientific Scimed, Inc. Cooled conductive balloon RF catheter for renal nerve ablation
US9084609B2 (en) 2010-07-30 2015-07-21 Boston Scientific Scime, Inc. Spiral balloon catheter for renal nerve ablation
EP2611476B1 (en) 2010-09-02 2016-08-10 Boston Scientific Scimed, Inc. Coating process for drug delivery balloons using heat-induced rewrap memory
US9446224B2 (en) 2010-09-22 2016-09-20 Vital 5, L.L.C. Barrier catheter
US8974451B2 (en) 2010-10-25 2015-03-10 Boston Scientific Scimed, Inc. Renal nerve ablation using conductive fluid jet and RF energy
US9220558B2 (en) 2010-10-27 2015-12-29 Boston Scientific Scimed, Inc. RF renal denervation catheter with multiple independent electrodes
EP2637608B1 (en) 2010-11-12 2016-03-02 Silver Bullet Therapeutics Inc. Bone implant and systems that controllably releases silver
US9028485B2 (en) 2010-11-15 2015-05-12 Boston Scientific Scimed, Inc. Self-expanding cooling electrode for renal nerve ablation
US9089350B2 (en) 2010-11-16 2015-07-28 Boston Scientific Scimed, Inc. Renal denervation catheter with RF electrode and integral contrast dye injection arrangement
US9668811B2 (en) 2010-11-16 2017-06-06 Boston Scientific Scimed, Inc. Minimally invasive access for renal nerve ablation
US9326751B2 (en) 2010-11-17 2016-05-03 Boston Scientific Scimed, Inc. Catheter guidance of external energy for renal denervation
US9060761B2 (en) 2010-11-18 2015-06-23 Boston Scientific Scime, Inc. Catheter-focused magnetic field induced renal nerve ablation
US9192435B2 (en) 2010-11-22 2015-11-24 Boston Scientific Scimed, Inc. Renal denervation catheter with cooled RF electrode
US9023034B2 (en) 2010-11-22 2015-05-05 Boston Scientific Scimed, Inc. Renal ablation electrode with force-activatable conduction apparatus
US20120157993A1 (en) 2010-12-15 2012-06-21 Jenson Mark L Bipolar Off-Wall Electrode Device for Renal Nerve Ablation
US9220561B2 (en) 2011-01-19 2015-12-29 Boston Scientific Scimed, Inc. Guide-compatible large-electrode catheter for renal nerve ablation with reduced arterial injury
US10278774B2 (en) 2011-03-18 2019-05-07 Covidien Lp Selectively expandable operative element support structure and methods of use
CA2832311A1 (en) 2011-04-08 2012-11-29 Covidien Lp Iontophoresis drug delivery system and method for denervation of the renal sympathetic nerve and iontophoretic drug delivery
CN103930061B (en) 2011-04-25 2016-09-14 美敦力阿迪安卢森堡有限责任公司 Relevant low temperature sacculus for restricted conduit wall cryogenic ablation limits the device and method disposed
WO2013013156A2 (en) 2011-07-20 2013-01-24 Boston Scientific Scimed, Inc. Percutaneous devices and methods to visualize, target and ablate nerves
EP2734264B1 (en) 2011-07-22 2018-11-21 Boston Scientific Scimed, Inc. Nerve modulation system with a nerve modulation element positionable in a helical guide
WO2013022458A1 (en) 2011-08-05 2013-02-14 Boston Scientific Scimed, Inc. Methods of converting amorphous drug substance into crystalline form
US9056152B2 (en) 2011-08-25 2015-06-16 Boston Scientific Scimed, Inc. Medical device with crystalline drug coating
WO2013055826A1 (en) 2011-10-10 2013-04-18 Boston Scientific Scimed, Inc. Medical devices including ablation electrodes
US10085799B2 (en) 2011-10-11 2018-10-02 Boston Scientific Scimed, Inc. Off-wall electrode device and methods for nerve modulation
US9420955B2 (en) 2011-10-11 2016-08-23 Boston Scientific Scimed, Inc. Intravascular temperature monitoring system and method
US9364284B2 (en) 2011-10-12 2016-06-14 Boston Scientific Scimed, Inc. Method of making an off-wall spacer cage
US9162046B2 (en) 2011-10-18 2015-10-20 Boston Scientific Scimed, Inc. Deflectable medical devices
US9079000B2 (en) 2011-10-18 2015-07-14 Boston Scientific Scimed, Inc. Integrated crossing balloon catheter
CN108095821B (en) 2011-11-08 2021-05-25 波士顿科学西美德公司 Orifice renal nerve ablation
WO2013074813A1 (en) 2011-11-15 2013-05-23 Boston Scientific Scimed, Inc. Device and methods for renal nerve modulation monitoring
US9119632B2 (en) 2011-11-21 2015-09-01 Boston Scientific Scimed, Inc. Deflectable renal nerve ablation catheter
US9265969B2 (en) 2011-12-21 2016-02-23 Cardiac Pacemakers, Inc. Methods for modulating cell function
AU2012358143B2 (en) 2011-12-23 2015-06-11 Boston Scientific Scimed, Inc. Expandable balloon or an electrode pad with a heat sensing device
US9433760B2 (en) 2011-12-28 2016-09-06 Boston Scientific Scimed, Inc. Device and methods for nerve modulation using a novel ablation catheter with polymeric ablative elements
US9050106B2 (en) 2011-12-29 2015-06-09 Boston Scientific Scimed, Inc. Off-wall electrode device and methods for nerve modulation
US8403927B1 (en) 2012-04-05 2013-03-26 William Bruce Shingleton Vasectomy devices and methods
US10660703B2 (en) 2012-05-08 2020-05-26 Boston Scientific Scimed, Inc. Renal nerve modulation devices
US9770293B2 (en) 2012-06-04 2017-09-26 Boston Scientific Scimed, Inc. Systems and methods for treating tissue of a passageway within a body
US9256531B2 (en) 2012-06-19 2016-02-09 Samsung Electronics Co., Ltd. Memory system and SoC including linear addresss remapping logic
US9592086B2 (en) 2012-07-24 2017-03-14 Boston Scientific Scimed, Inc. Electrodes for tissue treatment
CN104540465A (en) 2012-08-24 2015-04-22 波士顿科学西美德公司 Intravascular catheter with a balloon comprising separate microporous regions
WO2014043687A2 (en) 2012-09-17 2014-03-20 Boston Scientific Scimed, Inc. Self-positioning electrode system and method for renal nerve modulation
WO2014047411A1 (en) 2012-09-21 2014-03-27 Boston Scientific Scimed, Inc. System for nerve modulation and innocuous thermal gradient nerve block
WO2014047454A2 (en) 2012-09-21 2014-03-27 Boston Scientific Scimed, Inc. Self-cooling ultrasound ablation catheter
JP6074051B2 (en) 2012-10-10 2017-02-01 ボストン サイエンティフィック サイムド,インコーポレイテッドBoston Scientific Scimed,Inc. Intravascular neuromodulation system and medical device
US9272132B2 (en) 2012-11-02 2016-03-01 Boston Scientific Scimed, Inc. Medical device for treating airways and related methods of use
US9283374B2 (en) 2012-11-05 2016-03-15 Boston Scientific Scimed, Inc. Devices and methods for delivering energy to body lumens
US10286182B2 (en) * 2012-11-12 2019-05-14 Boston Scientific Scimed, Inc. Renal catheter shaft design
US9398933B2 (en) 2012-12-27 2016-07-26 Holaira, Inc. Methods for improving drug efficacy including a combination of drug administration and nerve modulation
WO2014163987A1 (en) 2013-03-11 2014-10-09 Boston Scientific Scimed, Inc. Medical devices for modulating nerves
WO2014143571A1 (en) 2013-03-11 2014-09-18 Boston Scientific Scimed, Inc. Medical devices for modulating nerves
US9808311B2 (en) 2013-03-13 2017-11-07 Boston Scientific Scimed, Inc. Deflectable medical devices
US9669194B2 (en) 2013-03-14 2017-06-06 W. L. Gore & Associates, Inc. Conformable balloon devices and methods
US10265122B2 (en) 2013-03-15 2019-04-23 Boston Scientific Scimed, Inc. Nerve ablation devices and related methods of use
CN105228546B (en) 2013-03-15 2017-11-14 波士顿科学国际有限公司 Utilize the impedance-compensated medicine equipment and method that are used to treat hypertension
US9827039B2 (en) 2013-03-15 2017-11-28 Boston Scientific Scimed, Inc. Methods and apparatuses for remodeling tissue of or adjacent to a body passage
US9814618B2 (en) 2013-06-06 2017-11-14 Boston Scientific Scimed, Inc. Devices for delivering energy and related methods of use
EP3010437A1 (en) 2013-06-21 2016-04-27 Boston Scientific Scimed, Inc. Renal denervation balloon catheter with ride along electrode support
JP2016524949A (en) 2013-06-21 2016-08-22 ボストン サイエンティフィック サイムド,インコーポレイテッドBoston Scientific Scimed,Inc. Medical device for renal nerve ablation having a rotatable shaft
US9707036B2 (en) 2013-06-25 2017-07-18 Boston Scientific Scimed, Inc. Devices and methods for nerve modulation using localized indifferent electrodes
AU2014284558B2 (en) 2013-07-01 2017-08-17 Boston Scientific Scimed, Inc. Medical devices for renal nerve ablation
US10660698B2 (en) 2013-07-11 2020-05-26 Boston Scientific Scimed, Inc. Devices and methods for nerve modulation
EP3019106A1 (en) 2013-07-11 2016-05-18 Boston Scientific Scimed, Inc. Medical device with stretchable electrode assemblies
EP3049007B1 (en) 2013-07-19 2019-06-12 Boston Scientific Scimed, Inc. Spiral bipolar electrode renal denervation balloon
JP6122217B2 (en) 2013-07-22 2017-04-26 ボストン サイエンティフィック サイムド,インコーポレイテッドBoston Scientific Scimed,Inc. Renal nerve ablation medical device
WO2015013205A1 (en) 2013-07-22 2015-01-29 Boston Scientific Scimed, Inc. Medical devices for renal nerve ablation
US10478247B2 (en) 2013-08-09 2019-11-19 Boston Scientific Scimed, Inc. Expandable catheter and related methods of manufacture and use
CN105473093B (en) 2013-08-22 2019-02-05 波士顿科学国际有限公司 Flexible circuit with the improved adhesion strength to renal nerve modulation sacculus
CN105555218B (en) 2013-09-04 2019-01-15 波士顿科学国际有限公司 With radio frequency (RF) foley's tube rinsed with cooling capacity
EP3043733A1 (en) 2013-09-13 2016-07-20 Boston Scientific Scimed, Inc. Ablation balloon with vapor deposited cover layer
US11246654B2 (en) 2013-10-14 2022-02-15 Boston Scientific Scimed, Inc. Flexible renal nerve ablation devices and related methods of use and manufacture
US9687166B2 (en) 2013-10-14 2017-06-27 Boston Scientific Scimed, Inc. High resolution cardiac mapping electrode array catheter
WO2015057584A1 (en) 2013-10-15 2015-04-23 Boston Scientific Scimed, Inc. Medical device balloon
US9770606B2 (en) 2013-10-15 2017-09-26 Boston Scientific Scimed, Inc. Ultrasound ablation catheter with cooling infusion and centering basket
WO2015057961A1 (en) 2013-10-18 2015-04-23 Boston Scientific Scimed, Inc. Balloon catheters with flexible conducting wires and related methods of use and manufacture
WO2015061457A1 (en) 2013-10-25 2015-04-30 Boston Scientific Scimed, Inc. Embedded thermocouple in denervation flex circuit
US10286190B2 (en) 2013-12-11 2019-05-14 Cook Medical Technologies Llc Balloon catheter with dynamic vessel engaging member
WO2015103617A1 (en) 2014-01-06 2015-07-09 Boston Scientific Scimed, Inc. Tear resistant flex circuit assembly
EP2898920B1 (en) 2014-01-24 2018-06-06 Cook Medical Technologies LLC Articulating balloon catheter
US11000679B2 (en) 2014-02-04 2021-05-11 Boston Scientific Scimed, Inc. Balloon protection and rewrapping devices and related methods of use
EP3102136B1 (en) 2014-02-04 2018-06-27 Boston Scientific Scimed, Inc. Alternative placement of thermal sensors on bipolar electrode
US10709490B2 (en) 2014-05-07 2020-07-14 Medtronic Ardian Luxembourg S.A.R.L. Catheter assemblies comprising a direct heating element for renal neuromodulation and associated systems and methods
US9452242B2 (en) 2014-06-11 2016-09-27 Silver Bullet Therapeutics, Inc. Enhancement of antimicrobial silver, silver coatings, or silver platings
GB201412842D0 (en) * 2014-07-18 2014-09-03 Combat Medical Sl Catheter for the delivery of therapeutic fluid
JP2016163655A (en) * 2015-03-06 2016-09-08 オリンパス株式会社 Nerve stimulation device
US11337749B2 (en) 2015-10-07 2022-05-24 Mayo Foundation For Medical Education And Research Electroporation for obesity or diabetes treatment
KR20190073371A (en) * 2016-10-20 2019-06-26 레트로배스큘러, 아이엔씨. Methods and devices for increased composition delivery
USD876569S1 (en) 2018-05-29 2020-02-25 Placements Gaston Houle Inc. Quiver
USD870227S1 (en) 2018-05-29 2019-12-17 Placements Gaston Houle Inc. Quiver
US10612881B2 (en) 2017-12-01 2020-04-07 Placements Gaston Houle Inc. Quiver securing mechanism
US11116561B2 (en) 2018-01-24 2021-09-14 Medtronic Ardian Luxembourg S.A.R.L. Devices, agents, and associated methods for selective modulation of renal nerves

Family Cites Families (55)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US600290A (en) * 1898-03-08 Therapeutic electrode
US578611A (en) * 1897-03-09 Thirds to louis f
US791730A (en) * 1903-06-01 1905-06-06 Johan Jakob Stanger Electrical mouth-bath.
US866180A (en) * 1907-06-13 1907-09-17 Cutler Taylor Ball Combined applicator and dilator.
US873021A (en) * 1907-08-02 1907-12-10 Harlow R Cool Electrotherapeutic syringe.
US2123920A (en) * 1934-06-01 1938-07-19 Servel Inc Refrigeration
US2123980A (en) * 1934-07-21 1938-07-19 G M Basford Company Therapeutic treatment
US3411507A (en) * 1964-04-01 1968-11-19 Medtronic Inc Method of gastrointestinal stimulation with electrical pulses
US3618601A (en) * 1969-10-16 1971-11-09 Thatcher W Richardson Iontophoresis unit
US3716054A (en) * 1970-08-11 1973-02-13 W Porter Apparatus for applying medication to teeth and body tissue
US3991755A (en) * 1973-07-27 1976-11-16 Medicon, Inc. Iontophoresis apparatus for applying local anesthetics
US4309989A (en) * 1976-02-09 1982-01-12 The Curators Of The University Of Missouri Topical application of medication by ultrasound with coupling agent
SU843999A1 (en) * 1977-10-11 1981-07-07 Харьковская Областная Клиническаябольница Probe for intracavitary electrophoresis
US4250878A (en) * 1978-11-22 1981-02-17 Motion Control, Inc. Non-invasive chemical species delivery apparatus and method
US4383529A (en) * 1980-11-03 1983-05-17 Wescor, Inc. Iontophoretic electrode device, method and gel insert
US4405311A (en) * 1980-12-08 1983-09-20 Greatbatch Enterprises, Inc. Method and apparatus for direct electrical injection of gold ions into tissue such as bone
US4411648A (en) * 1981-06-11 1983-10-25 Board Of Regents, The University Of Texas System Iontophoretic catheter device
US4417576A (en) * 1982-02-25 1983-11-29 Baran Ostap E Double-wall surgical cuff
US4423725A (en) * 1982-03-31 1984-01-03 Baran Ostap E Multiple surgical cuff
US4636195A (en) * 1982-04-02 1987-01-13 Harvey Wolinsky Method and apparatus for removing arterial constriction
SU1069826A1 (en) * 1982-09-17 1984-01-30 Запорожский медицинский институт Endotracheal tube
SU1069827A1 (en) * 1982-09-17 1984-01-30 Запорожский медицинский институт Endotracheal tube
US4545390A (en) 1982-09-22 1985-10-08 C. R. Bard, Inc. Steerable guide wire for balloon dilatation procedure
US4522194A (en) * 1983-02-18 1985-06-11 Baylor College Of Medicine Method and an apparatus for intra-aortic balloon monitoring and leak detection
US4581017B1 (en) 1983-03-07 1994-05-17 Bard Inc C R Catheter systems
FR2542886B1 (en) * 1983-03-15 1985-08-16 Tecnimatic METHOD AND DEVICE FOR TIGHTENING SCREWS OR THE LIKE TO THE LIMIT OF ELASTIC DEFORMATION
US4506680A (en) * 1983-03-17 1985-03-26 Medtronic, Inc. Drug dispensing body implantable lead
JPS6052592A (en) * 1983-09-02 1985-03-25 Nisshin Steel Co Ltd Treatment of zn-ni alloy electroplated steel sheet after plating
US4569673A (en) * 1984-01-12 1986-02-11 Battelle Development Corporation Bacterial barrier for indwelling catheters and other medical devices
US4574807A (en) * 1984-03-02 1986-03-11 Carl Hewson Method and apparatus for pacing the heart employing external and internal electrodes
US5135477A (en) * 1984-10-29 1992-08-04 Medtronic, Inc. Iontophoretic drug delivery
US4577642A (en) * 1985-02-27 1986-03-25 Medtronic, Inc. Drug dispensing body implantable lead employing molecular sieves and methods of fabrication
AT385894B (en) * 1985-10-04 1988-05-25 Basem Dr Nashef TUBULAR PROBE
US4752285B1 (en) * 1986-03-19 1995-08-22 Univ Utah Res Found Methods and apparatus for iontophoresis application of medicaments
US4915685A (en) * 1986-03-19 1990-04-10 Petelenz Tomasz J Methods and apparatus for iontophoresis application of medicaments at a controlled ph through ion exchange
US4877831B1 (en) * 1986-06-17 1993-12-21 Mitsubishi Rayon Co.,Ltd. Polycarbonate resin composition
US4767402A (en) * 1986-07-08 1988-08-30 Massachusetts Institute Of Technology Ultrasound enhancement of transdermal drug delivery
US5042975A (en) * 1986-07-25 1991-08-27 Rutgers, The State University Of New Jersey Iontotherapeutic device and process and iontotherapeutic unit dose
US5250022A (en) * 1990-09-25 1993-10-05 Rutgers, The State University Of New Jersey Iontotherapeutic devices, reservoir electrode devices therefore, process and unit dose
IN171162B (en) * 1987-05-20 1992-08-08 Rieter Ag Switzerland Maschf
US4892519A (en) * 1987-12-03 1990-01-09 Advanced Cardiovascular Systems, Inc. Steerable perfusion dilatation catheter
JP2798459B2 (en) * 1988-01-21 1998-09-17 マサチユセツツ・インスチチユート・オブ・テクノロジー Diagnostic device using electroporation and device for moving molecules into tissue
US4944745A (en) * 1988-02-29 1990-07-31 Scimed Life Systems, Inc. Perfusion balloon catheter
DE3809815A1 (en) * 1988-03-23 1989-10-12 Peter Zimmer Internal electrode for introduction in a body cavity
US4877031A (en) * 1988-07-22 1989-10-31 Advanced Cardiovascular Systems, Inc. Steerable perfusion dilatation catheter
DE3915636C1 (en) * 1989-05-12 1990-04-26 Sass, Wolfgang, Dr.
US4994033A (en) * 1989-05-25 1991-02-19 Schneider (Usa) Inc. Intravascular drug delivery dilatation catheter
DK0438078T3 (en) * 1990-01-15 1996-10-21 Cino Rossi iontophoresis device
US5236413B1 (en) * 1990-05-07 1996-06-18 Andrew J Feiring Method and apparatus for inducing the permeation of medication into internal tissue
DE69110467T2 (en) * 1990-06-15 1996-02-01 Cortrak Medical Inc DEVICE FOR DISPENSING MEDICINES.
US5498238A (en) * 1990-06-15 1996-03-12 Cortrak Medical, Inc. Simultaneous angioplasty and phoretic drug delivery
DE4224360A1 (en) * 1991-07-26 1993-01-28 Nissan Motor AUTOMATIC TRANSMISSION DESIGN
US5232441A (en) * 1992-05-18 1993-08-03 Physion S.R.L. Method of treating schistosomal infestations by iontophoresis
US5304120A (en) * 1992-07-01 1994-04-19 Btx Inc. Electroporation method and apparatus for insertion of drugs and genes into endothelial cells
US5256141A (en) * 1992-12-22 1993-10-26 Nelson Gencheff Biological material deployment method and apparatus

Also Published As

Publication number Publication date
DE69132787D1 (en) 2001-11-29
JP3372250B2 (en) 2003-01-27
EP1002554B1 (en) 2001-10-24
AU7901091A (en) 1991-11-27
DE69132438D1 (en) 2000-11-09
AU642020B2 (en) 1993-10-07
WO1991016945A1 (en) 1991-11-14
ATE207375T1 (en) 2001-11-15
DE69132787T2 (en) 2002-08-01
DE69132438T2 (en) 2001-05-10
US6195583B1 (en) 2001-02-27
JPH05508782A (en) 1993-12-09
US20010001816A1 (en) 2001-05-24
US5236413B1 (en) 1996-06-18
US5425703A (en) 1995-06-20
EP0527920A1 (en) 1993-02-24
US6389314B2 (en) 2002-05-14
CA2081666C (en) 1998-12-29
US5549603A (en) 1996-08-27
US5669874A (en) 1997-09-23
EP1002554A1 (en) 2000-05-24
ATE196740T1 (en) 2000-10-15
US5236413A (en) 1993-08-17
US5810763A (en) 1998-09-22
EP0527920B1 (en) 2000-10-04
EP0527920A4 (en) 1993-07-28

Similar Documents

Publication Publication Date Title
US5236413B1 (en) Method and apparatus for inducing the permeation of medication into internal tissue
AU5306094A (en) Intravenous cardiac lead with improved fixation and method
EP0260711A3 (en) Procedure and catheter instrument for treating patients for aortic stenosis
CA2147142A1 (en) Method and Apparatus for Providing Light-Activated Therapy
EP0249338A3 (en) Retroperfusion catheter
ATE63826T1 (en) PUMP BODY FOR CONNECTING AN RADIATION CHAMBER TO A SYSTEM FOR TREATMENT OF A PATIENT BY PHOTOACTIVATION.
HU910979D0 (en) Process for the prodiction of medical preparations with n-neuropeptide-antagonistic effect, containing guanidine derivatives
SE452405B (en) HEART-LUNGE SYSTEM PROVIDED FOR ACIDING A PATIENT&#39;S BLOOD
DE3264419D1 (en) Surgical dressing for fixing a probe
AU4253389A (en) Apparatus for observation and/or treatment of a seated or recumbent patient
EP0324802A4 (en) Method for the treatment of body tissues and the administration of drugs thereto
DE59407579D1 (en) X-ray diagnostic device for taking X-rays of parts of a patient&#39;s body
DE3879220D1 (en) REDUCTION OF LOW DENSITY LIPOPROTEINS IN BIOLOGICAL LIQUIDS.
EP0252594A3 (en) Portable electro-therapy system
YU48610B (en) Derivatives of nitratoalkanocarbonic acids and process for obtaining them
AU2443888A (en) Agents for treating high blood pressure and cardiac insufficiency
GR3017672T3 (en) Therapeutic agent for diabetic gangrene.
SU1437034A1 (en) Catheter for angiography
SU1710069A1 (en) Device for intracavitary electrophoresis
DE69302167T2 (en) DEVICE FOR QUICK CONNECTION TO THE BLOOD CIRCUIT
RU93018885A (en) METHOD FOR TREATING HEPATIC INSUFFICIENCY
UA10221A (en) Method for treatment of recurrent bronchitis in children
PL277468A1 (en) Apparatus for surgical treatment of astigmatism
AU4252889A (en) Apparatus for positioning the head of a patient, notably during an ophthalmological examination or treatment
RU94002982A (en) METHOD OF TREATMENT OF OSTEOARTHROSIS

Legal Events

Date Code Title Description
EEER Examination request
MKLA Lapsed