CA2084523C - Variable stiffness catheter - Google Patents
Variable stiffness catheterInfo
- Publication number
- CA2084523C CA2084523C CA002084523A CA2084523A CA2084523C CA 2084523 C CA2084523 C CA 2084523C CA 002084523 A CA002084523 A CA 002084523A CA 2084523 A CA2084523 A CA 2084523A CA 2084523 C CA2084523 C CA 2084523C
- Authority
- CA
- Canada
- Prior art keywords
- catheter
- segment
- proximal
- distal
- wall thickness
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Expired - Fee Related
Links
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
- A61M25/00—Catheters; Hollow probes
- A61M25/0043—Catheters; Hollow probes characterised by structural features
- A61M25/0054—Catheters; Hollow probes characterised by structural features with regions for increasing flexibility
Abstract
A catheter composed of an outer coaxial tube or relatively high flexibility and three tandemly disposed inner coaxial tube segments that vary in stiffness with the stiffest being located at the proximal end of the catheter and the least stiff ending proximal of the proximal end of the catheter. The catheter thus has four regions of different stiffness/flexibility.
Description
- - 2~84~23 VARIA~3LE STIFFNESS CA~ K
Description Technical Field This invention is in the general field of surgical devices and relates specifically to an improved catheter tube structure that may be used with a guide wire to access target sites through tortuous, small diameter vessels with less likelihood of kinking or other malfunction.
Bac~qround Catheters are hollow tubes that are inserted through the vasculature or other internal body passageways to access a particular internal body site for various diagnostic or therapeutic purposes. Angiography catheters are used to deliver radiopaque agents to a target site to enable radiographic visualization of the site. In the treatment of localized diseases such as solid tumors, they are used to ~Am~nister chemothera-peutic agents or vasoocclusive agents. Catheters are similarly used to deliver vasoocclusive devices (e.g., coils) to sites of aneurysm. Inflatable catheters, often referred to as balloon catheters, are used to dilate vessels.
For insertion through tortuous, small vessels such a~ those found in the peripheral vasculature or organs such as the brain and liver, catheters are c~mmo~ly used in combination with a flexible torqueable *
- ,2qJ8~5:23 guide wire. In this procedure, the guide wire is advanced through the vessel and the catheter is threaded over the guide wire. At tortuous sites in the vessel, the assembly is advanced by alternately guiding the wire through the site and then threading the catheter over the advanced segment of the wire. In order to be useful in such applications, the catheter must meet d~m~n~;ng physical requirements so that it does not become locked - against the guide wire or become kinked as it is passed through particularly tortuous segments of the vessel. In this regard, commonly owned U.S. Patent 4,739,76a describes a catheter structure specifically designed to overcome problems associated with accessing tortuous, small vessels.
The specific catheter embodiment shown in U.S.
Patent 4,739,768 consists of a coaxial assembly of two tubes, one `of which is relatively long and stiff and defines a proximal portion of the catheter and the other of which is relatively short and flexible and defines the distal end of the catheter. The flexible distal end allows the catheter to be advanced axially over sharper and/or more frequent wire bends with less likelihood of malfunction. The patent mentions (col. 5) that for longer tortuous paths the catheter may include one or more intermeA;Ate segments having flexibilities intermediate those of the proximal and distal portions of the catheter and which, together with the distal portion, constitute 10~ to 40~ of the catheter length. The stated purpose of such interm~A;~te sections is to provide greater column strength than the distal portion of the two-section emboA;mPnt and greater flexibility than the proximal section of that emboA;m~nt. The patent does not provide any specific examples of such multi-segment catheter~ ~r indicate any other purposes of a multi-segment structure.
The present in~ention relates to a catheter which has four segments of different flexibility. This novel structure improves on the performance and durability of the two-qegment structure depicted in U.S.
Patent 4,739,768.
Disclosure of the Invention The in~ention is a catheter for use in combiDRtion with a guide wire for placement within a tortuous, small vessel, said catheter comprising an elongate tubular body having proxim~l a~d distal ends and a lumen extending between said ends for receiving the 1~ guide wire, said body comprising:
(a) an suter co~Yi~l tube extending con~in~lously between said ends, having a wall thickness of O.OS to 0.13 G and being made of a polymer having a flexural modulus o~ abcutloo,ooO to 250,00 kpa; and (b~ pr~xim~l, int~rme~;~te, and distal inner cs~Y;~l polymeric tube segments positioned contiguously in t~nAPm within the outer tube from said proxim~l end to a site proxi m~ l said distal end, the pro~; m~ 1 segment having a wall thickness Of 0.08 to ~.18 mm and being made 2s of a polymer ha~ing a flexural modulu9 of about l,5oo,ooo to 1,8~0,000 kpa, the intermediate segment being less stiff than the prox;m~l segment and the distal segment being less stiff than the intermediate segment but stiffer than the portion of the outer tube extending from said site to said distal end.
208~2~
~rief Description of the Drawings Figure I is an elevational view of a catheter assembly showing the catheter of the invention in combination with a guide wire.
Figure 2 i9 an enlarged sectional view of a portion of the catheter of the invention showing the coaxial segmented structure of the catheter.
Figures 3A and 3~3 are sectional schematic views which show how the prior art structure (3A) may perform at a sharp bend as compared to the invention structure (3~).
Detailed Description of the Invention Figure 1 is a general view showing a catheter assembly, generally designated 11, that includes the inventive catheter 12 in combination with a guide wire 13. The details of the catheter construction that distinguish it from prior structures are not shown in Figure 1. The assembly includes a standard fitting 14 through which the guide wire is received and to which the proximal end lS of the catheter is removably attached.
- As depicted, the catheter is a continuous tubular body that extends from proximal end 15 to distal end 16 and through which the guide wire extends. The distal end of the guide wire extends outwardly of the distal end 16 of the catheter. The distal region of the catheter typically carries one or more radiopaque bands 17 90 that the location of the distal region of the catheter within the vessel may be visualized radiographically.
Details of the structure of catheter 12 are depicted in Figure 2. It is composed of an outer tube 18 and three inner co~Y; Al tubular segments 19, 20, 21. As shown, the three inner co~Y~l tubular segments are disposed in t~nAPm within the outer tube and are ~ 0 ~ 2 3 contiguou~ to each other (i.e., their respective ends abut each other). The outer tube 18 extends continuously o~e-r the entire length of the catheter, which typically will be o~er S0 to 210 cm, more usually 80 to lS0 cm.
The outer diameter of tube 18 (as measured at proximal end lS) will normally be 0.75 to 2.00 mm, preferably 0.85 to i.30 mm. As seen in Figure 2, the outer tube may neck down at its distal end and its outer diameter at the distal end may be slightly smaller than at its pro~;m~l end. The outer tube will nonmally ha~e a wall thickness of about 0.08 to 0.16 mm, preferably about 0.10 to 0.13 mm. It is made from a palymer having a flexural modulus (as measured by ASTM D-7gO) of about loo,ooo to 25U,OOO kpa, such as low density polyethylene.
lS The-proY;m~l inner tt~h~ r segment 19 extends from the proxim~l end lS of the catheter to junction 22.
This distance will normally ~e 10 to 70 cm, more usually 40 to 60 cm, and preferably about S0 cm. Its wall thi~kne~9 i9 about 0.08 to 0.18 mm, preferably about 0.10 to 0.13 mm, and it is made of a polymer ha~ing a flexural modulus of about 1,500,000 to 1,800,000 kpa such as polypropylene. The portion of the catheter from pr~xim~l end lS to junction 22 is thus the stiffest portion of the catheter. The inner diameter of ~egment 19 will normally 2~ ~e 0.45 to 0.75 mm.
Intermediate inner tubular segment 20 extends from the distal end of segment 19 (junction 22) to junction 23. That distance will normally be 30 to 100 cm, more normally 70 to 90 cm, preferably about 80 cm.
Description Technical Field This invention is in the general field of surgical devices and relates specifically to an improved catheter tube structure that may be used with a guide wire to access target sites through tortuous, small diameter vessels with less likelihood of kinking or other malfunction.
Bac~qround Catheters are hollow tubes that are inserted through the vasculature or other internal body passageways to access a particular internal body site for various diagnostic or therapeutic purposes. Angiography catheters are used to deliver radiopaque agents to a target site to enable radiographic visualization of the site. In the treatment of localized diseases such as solid tumors, they are used to ~Am~nister chemothera-peutic agents or vasoocclusive agents. Catheters are similarly used to deliver vasoocclusive devices (e.g., coils) to sites of aneurysm. Inflatable catheters, often referred to as balloon catheters, are used to dilate vessels.
For insertion through tortuous, small vessels such a~ those found in the peripheral vasculature or organs such as the brain and liver, catheters are c~mmo~ly used in combination with a flexible torqueable *
- ,2qJ8~5:23 guide wire. In this procedure, the guide wire is advanced through the vessel and the catheter is threaded over the guide wire. At tortuous sites in the vessel, the assembly is advanced by alternately guiding the wire through the site and then threading the catheter over the advanced segment of the wire. In order to be useful in such applications, the catheter must meet d~m~n~;ng physical requirements so that it does not become locked - against the guide wire or become kinked as it is passed through particularly tortuous segments of the vessel. In this regard, commonly owned U.S. Patent 4,739,76a describes a catheter structure specifically designed to overcome problems associated with accessing tortuous, small vessels.
The specific catheter embodiment shown in U.S.
Patent 4,739,768 consists of a coaxial assembly of two tubes, one `of which is relatively long and stiff and defines a proximal portion of the catheter and the other of which is relatively short and flexible and defines the distal end of the catheter. The flexible distal end allows the catheter to be advanced axially over sharper and/or more frequent wire bends with less likelihood of malfunction. The patent mentions (col. 5) that for longer tortuous paths the catheter may include one or more intermeA;Ate segments having flexibilities intermediate those of the proximal and distal portions of the catheter and which, together with the distal portion, constitute 10~ to 40~ of the catheter length. The stated purpose of such interm~A;~te sections is to provide greater column strength than the distal portion of the two-section emboA;mPnt and greater flexibility than the proximal section of that emboA;m~nt. The patent does not provide any specific examples of such multi-segment catheter~ ~r indicate any other purposes of a multi-segment structure.
The present in~ention relates to a catheter which has four segments of different flexibility. This novel structure improves on the performance and durability of the two-qegment structure depicted in U.S.
Patent 4,739,768.
Disclosure of the Invention The in~ention is a catheter for use in combiDRtion with a guide wire for placement within a tortuous, small vessel, said catheter comprising an elongate tubular body having proxim~l a~d distal ends and a lumen extending between said ends for receiving the 1~ guide wire, said body comprising:
(a) an suter co~Yi~l tube extending con~in~lously between said ends, having a wall thickness of O.OS to 0.13 G and being made of a polymer having a flexural modulus o~ abcutloo,ooO to 250,00 kpa; and (b~ pr~xim~l, int~rme~;~te, and distal inner cs~Y;~l polymeric tube segments positioned contiguously in t~nAPm within the outer tube from said proxim~l end to a site proxi m~ l said distal end, the pro~; m~ 1 segment having a wall thickness Of 0.08 to ~.18 mm and being made 2s of a polymer ha~ing a flexural modulu9 of about l,5oo,ooo to 1,8~0,000 kpa, the intermediate segment being less stiff than the prox;m~l segment and the distal segment being less stiff than the intermediate segment but stiffer than the portion of the outer tube extending from said site to said distal end.
208~2~
~rief Description of the Drawings Figure I is an elevational view of a catheter assembly showing the catheter of the invention in combination with a guide wire.
Figure 2 i9 an enlarged sectional view of a portion of the catheter of the invention showing the coaxial segmented structure of the catheter.
Figures 3A and 3~3 are sectional schematic views which show how the prior art structure (3A) may perform at a sharp bend as compared to the invention structure (3~).
Detailed Description of the Invention Figure 1 is a general view showing a catheter assembly, generally designated 11, that includes the inventive catheter 12 in combination with a guide wire 13. The details of the catheter construction that distinguish it from prior structures are not shown in Figure 1. The assembly includes a standard fitting 14 through which the guide wire is received and to which the proximal end lS of the catheter is removably attached.
- As depicted, the catheter is a continuous tubular body that extends from proximal end 15 to distal end 16 and through which the guide wire extends. The distal end of the guide wire extends outwardly of the distal end 16 of the catheter. The distal region of the catheter typically carries one or more radiopaque bands 17 90 that the location of the distal region of the catheter within the vessel may be visualized radiographically.
Details of the structure of catheter 12 are depicted in Figure 2. It is composed of an outer tube 18 and three inner co~Y; Al tubular segments 19, 20, 21. As shown, the three inner co~Y~l tubular segments are disposed in t~nAPm within the outer tube and are ~ 0 ~ 2 3 contiguou~ to each other (i.e., their respective ends abut each other). The outer tube 18 extends continuously o~e-r the entire length of the catheter, which typically will be o~er S0 to 210 cm, more usually 80 to lS0 cm.
The outer diameter of tube 18 (as measured at proximal end lS) will normally be 0.75 to 2.00 mm, preferably 0.85 to i.30 mm. As seen in Figure 2, the outer tube may neck down at its distal end and its outer diameter at the distal end may be slightly smaller than at its pro~;m~l end. The outer tube will nonmally ha~e a wall thickness of about 0.08 to 0.16 mm, preferably about 0.10 to 0.13 mm. It is made from a palymer having a flexural modulus (as measured by ASTM D-7gO) of about loo,ooo to 25U,OOO kpa, such as low density polyethylene.
lS The-proY;m~l inner tt~h~ r segment 19 extends from the proxim~l end lS of the catheter to junction 22.
This distance will normally ~e 10 to 70 cm, more usually 40 to 60 cm, and preferably about S0 cm. Its wall thi~kne~9 i9 about 0.08 to 0.18 mm, preferably about 0.10 to 0.13 mm, and it is made of a polymer ha~ing a flexural modulus of about 1,500,000 to 1,800,000 kpa such as polypropylene. The portion of the catheter from pr~xim~l end lS to junction 22 is thus the stiffest portion of the catheter. The inner diameter of ~egment 19 will normally 2~ ~e 0.45 to 0.75 mm.
Intermediate inner tubular segment 20 extends from the distal end of segment 19 (junction 22) to junction 23. That distance will normally be 30 to 100 cm, more normally 70 to 90 cm, preferably about 80 cm.
3 0 Thi9 segment is les~ stiff than segment 19. Accordingly, its wall thickness is less than segment 19 and/or it i9 made of a ~lymer with a lower flexural modulus than the polymer forming segment 19 In a preferred em~odiment, it is made of the same polymer and has a smaller wall 3~
-6- 208-~523 thickness, normally 0.05 to 0.13 mm, more usually 0.05 to 0.0~ mm. In the preferred embodiments segments 19 and 20 may be made of a continuous length of tubing having an appropriately tapered outer diameter.
The third distal segment 21 extends from the distal end of segment 20 (junction 23) to a site 24 proximal of the distal end of the catheter. The distance from junction 23 to site 24 will usually be S to 20 cm, more usually 7 to 15 cm, preferably about 10 cm.
Corresponding, the distance from site 24 to the distal end 16 of the catheter will usually be S to 20 cm, more usually 7 to 15 cm, and preferably about 10 cm. me distance from junction 22 to the distal end o~ the catheter will be greater than about 50~ of the entire length of catheter 12, more usually greater than about 60~ of the entire catheter length. Segment 21 i8 les~
stiff than ~egment 20 and provides a transition in flexibility between segment 20 and the portion of outer tube 18 that extends-beyond site 24. It follows that the wall thickness of segment 21 is less than that of segment 20 and/or it is made from a polymer having a lower flexural modulus than the polymer forming segment 20. In this regard, it is preferable that segment 21 be made of a polymer having a ~ignificantly lower flexural modulus than the polymer forming segment 20 but higher than that of the polymer from which the outer tube 13 i8 made. The di~tal segment 21, for instance, may be linear, low density polyethylene Typically, the flexural modulus of the polymer forming segment 21 will be 150,000 to 375,()00 kpa, more 30 usually 20U,000 to 300,000 kpa. The wall thickness of segment 21 will normally be 0.05 to 0.10 mm, preferably 0.06 to 0.09 mm. The inner diameters of segments 20 and 21 are preferably substantially the same as that of segment 19.
~' 2Q84~23 Although the joints 22 and 23 are depicted as butt joints in the drawings, these joints may be overlap joints.
The invention catheter thus has four segment~
of different flexibility/stiffness and becomes increasingly flexible from segment-to-segment distally.
The axial flexibility/stiffness gradient of the invention catheter i9 thus more gradual than in the two-segment em~odiment of U.S. 4,739,768 and the change in flexibility stiffness between segment~ is not as great as in said two-segment embodiment. In particular, the inclusion of segment 21 allows the distal end of the catheter to be tracked around sharp bends with less likelihood of kinking occurring at the transition between the outer tube and the distal end of the inner coaxial tubing. This difference is shown in Figures 3A and 3B.
Figure 3A represents the prior art structure in which there was a greater change in flexibility/stiffness at the transition between the coaxial tube portion of the catheter and the single tube distal end. When the region was tracked through a sharp bend, kinking could occur at the transition. Such kinking h; n~ers the insertion (tracking) procedure and may lead to structural failure (delamination, separation) at the transition.
Figure 3B represents the invention structure in which the transition in flexibility/stiffness between the coaxial tube portion of the catheter and the single tube distal end is lessened. Such structure improves the trackability of the catheter through sharp bends (less likelihood of kinking) and reduces the likelihood of fatigue stress failure, ~el ~m; n~tion, or other structural failure at that transition.
Aside from its improved performance and durability, the invention catheter operates in the same ~5 - 2Q8~`3 manner as the catheter described in U.S. Patent 4,739,768. Similarly, it may be constructed using the same basic techniques as are set forth in U.S. Patent 4,739,76~. In view of this, detailed descriptions of the manufacture and operation of the invention catheter are not required herein.
Modifications of the above-described embodiments of the catheter that are obvious to those of skill in the fields of catheter design and manufacture, materials science, and related fields are intended to be within the scope of the following claims.
-6- 208-~523 thickness, normally 0.05 to 0.13 mm, more usually 0.05 to 0.0~ mm. In the preferred embodiments segments 19 and 20 may be made of a continuous length of tubing having an appropriately tapered outer diameter.
The third distal segment 21 extends from the distal end of segment 20 (junction 23) to a site 24 proximal of the distal end of the catheter. The distance from junction 23 to site 24 will usually be S to 20 cm, more usually 7 to 15 cm, preferably about 10 cm.
Corresponding, the distance from site 24 to the distal end 16 of the catheter will usually be S to 20 cm, more usually 7 to 15 cm, and preferably about 10 cm. me distance from junction 22 to the distal end o~ the catheter will be greater than about 50~ of the entire length of catheter 12, more usually greater than about 60~ of the entire catheter length. Segment 21 i8 les~
stiff than ~egment 20 and provides a transition in flexibility between segment 20 and the portion of outer tube 18 that extends-beyond site 24. It follows that the wall thickness of segment 21 is less than that of segment 20 and/or it is made from a polymer having a lower flexural modulus than the polymer forming segment 20. In this regard, it is preferable that segment 21 be made of a polymer having a ~ignificantly lower flexural modulus than the polymer forming segment 20 but higher than that of the polymer from which the outer tube 13 i8 made. The di~tal segment 21, for instance, may be linear, low density polyethylene Typically, the flexural modulus of the polymer forming segment 21 will be 150,000 to 375,()00 kpa, more 30 usually 20U,000 to 300,000 kpa. The wall thickness of segment 21 will normally be 0.05 to 0.10 mm, preferably 0.06 to 0.09 mm. The inner diameters of segments 20 and 21 are preferably substantially the same as that of segment 19.
~' 2Q84~23 Although the joints 22 and 23 are depicted as butt joints in the drawings, these joints may be overlap joints.
The invention catheter thus has four segment~
of different flexibility/stiffness and becomes increasingly flexible from segment-to-segment distally.
The axial flexibility/stiffness gradient of the invention catheter i9 thus more gradual than in the two-segment em~odiment of U.S. 4,739,768 and the change in flexibility stiffness between segment~ is not as great as in said two-segment embodiment. In particular, the inclusion of segment 21 allows the distal end of the catheter to be tracked around sharp bends with less likelihood of kinking occurring at the transition between the outer tube and the distal end of the inner coaxial tubing. This difference is shown in Figures 3A and 3B.
Figure 3A represents the prior art structure in which there was a greater change in flexibility/stiffness at the transition between the coaxial tube portion of the catheter and the single tube distal end. When the region was tracked through a sharp bend, kinking could occur at the transition. Such kinking h; n~ers the insertion (tracking) procedure and may lead to structural failure (delamination, separation) at the transition.
Figure 3B represents the invention structure in which the transition in flexibility/stiffness between the coaxial tube portion of the catheter and the single tube distal end is lessened. Such structure improves the trackability of the catheter through sharp bends (less likelihood of kinking) and reduces the likelihood of fatigue stress failure, ~el ~m; n~tion, or other structural failure at that transition.
Aside from its improved performance and durability, the invention catheter operates in the same ~5 - 2Q8~`3 manner as the catheter described in U.S. Patent 4,739,768. Similarly, it may be constructed using the same basic techniques as are set forth in U.S. Patent 4,739,76~. In view of this, detailed descriptions of the manufacture and operation of the invention catheter are not required herein.
Modifications of the above-described embodiments of the catheter that are obvious to those of skill in the fields of catheter design and manufacture, materials science, and related fields are intended to be within the scope of the following claims.
Claims (11)
1. A catheter for use in combination with a guide wire for placement within a tortuous, small vessel, said catheter comprising an elongate tubular body having proximal and distal ends and a lumen extending between said ends for receiving the guide wire, said body comprising:
(a) an outer coaxial tube extending continuously between said ends, having a wall thickness of 0.05 to 0.13 mm and being made of a polymer having a flexural modulus of about 100,000 to 250,000 kpa; and (b) proximal, intermediate, and distal inner coaxial polymeric tube segments positioned continguously in tandem within the outer tube from said proximal end to a site proximal said distal end, the proximal segment having a wall thickness of 0.08 to 0.18 mm and being made of a polymer having a flexural modulus of about 1,500,000 to 1,800,000 kpa the intermediate segment being less stiff than the proximal segment and the distal segment being less stiff than the intermediate segment but stiffer than the portion of the outer tube extending from said site to said distal end.
(a) an outer coaxial tube extending continuously between said ends, having a wall thickness of 0.05 to 0.13 mm and being made of a polymer having a flexural modulus of about 100,000 to 250,000 kpa; and (b) proximal, intermediate, and distal inner coaxial polymeric tube segments positioned continguously in tandem within the outer tube from said proximal end to a site proximal said distal end, the proximal segment having a wall thickness of 0.08 to 0.18 mm and being made of a polymer having a flexural modulus of about 1,500,000 to 1,800,000 kpa the intermediate segment being less stiff than the proximal segment and the distal segment being less stiff than the intermediate segment but stiffer than the portion of the outer tube extending from said site to said distal end.
2. The catheter of claim 1 wherein the proximal and intermediate segments are made of the same polymer and the wall thickness of the intermediate segment is less than the wall thickness of the proximal segment.
3. The catheter of claim 2 wherein the wall thickness of the intermediate segment is less than that of the proximal segment and is 0.05 to 0.13 mm
4. The catheter of claim 1 wherein the distal segment has a wall thickness of 0.05 to 0.10 mm and is made of a polymer having a flexural modulus of 150,000 to 375,000 kpa.
5. The catheter of claim 3 wherein the distal segment has a wall thickness less than that of the intermediate segment and is 0.06 to 0.11 mm and is made of a polymer having a flexural modulus of 200,000 to 300,000 kpa.
6. The catheter of claim 1 wherein the outer diameter of the outer coaxial tube is 0.75 to 2.00 mm at the proximal end and of a smaller diameter at the distal end.
7. The catheter of claim 6 wherein the length of the outer tube is 50 to 210 cm, the length of the proximal segment is 10 to 70 cm, the length of the intermediate segment is 30 to 100 cm, and the length of the distal segment is 5 to 20 cm.
8. The catheter of claim 1 wherein the distance from the distal end of the proximal segment to the distal end of the catheter constitutes greater than 50% of the length of the catheter.
9. The catheter of claim 1 wherein the distance from the distal end of the proximal segment to the distal end of the catheter constitutes greater than 60% of the length of the catheter.
10. The catheter of claim 1 wherein the outer tube is made of low density polyethylene, the proximal and intermediate segments are made of polypropylene, and the distal segment is made of linear low density polyethylene.
11. A catheter for use in combination with a guide wire for placement within a tortuous, small vessel, said catheter comprising an elongate tortuous, body having proximal and distal ends and a lumen extending between said ends for receiving the guide wire, said body comprising:
(a) an outer coaxial tube extending continuously between said ends, having a wall thickness of 0.05 to 0.13 mm and being made of a polymer having a flexural modulus of about 100,000 to 250,000 kpa; and (b) proximal, intermediate, and distal inner coaxial polymeric tube segments positioned contiguously in tandem within the outer tube from said proximal end to a site proximal said distal end, the proximal segment having a wall thickness of 0.08 to 0.18 mm and being made of a polymer having a flexural modulus of about 1,500,000 to 1,800,000 kpa the intermediate segment being less stiff than the proximal segment and the distal segment having a wall thickness of 0.05 to 0.10 mm and being made of a polymer having a flexural modulus of 150,000 to 375,000 kpa being less stiff than the intermediate segment but stiffer than the portion of the outer tube extending from said site to said distal end.
(a) an outer coaxial tube extending continuously between said ends, having a wall thickness of 0.05 to 0.13 mm and being made of a polymer having a flexural modulus of about 100,000 to 250,000 kpa; and (b) proximal, intermediate, and distal inner coaxial polymeric tube segments positioned contiguously in tandem within the outer tube from said proximal end to a site proximal said distal end, the proximal segment having a wall thickness of 0.08 to 0.18 mm and being made of a polymer having a flexural modulus of about 1,500,000 to 1,800,000 kpa the intermediate segment being less stiff than the proximal segment and the distal segment having a wall thickness of 0.05 to 0.10 mm and being made of a polymer having a flexural modulus of 150,000 to 375,000 kpa being less stiff than the intermediate segment but stiffer than the portion of the outer tube extending from said site to said distal end.
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US741,775 | 1991-08-07 | ||
| US07/741,775 US5308342A (en) | 1991-08-07 | 1991-08-07 | Variable stiffness catheter |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| CA2084523A1 CA2084523A1 (en) | 1993-02-08 |
| CA2084523C true CA2084523C (en) | 1996-04-23 |
Family
ID=24982137
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| CA002084523A Expired - Fee Related CA2084523C (en) | 1991-08-07 | 1992-08-03 | Variable stiffness catheter |
Country Status (12)
| Country | Link |
|---|---|
| US (1) | US5308342A (en) |
| EP (1) | EP0598025A4 (en) |
| JP (1) | JP2589943B2 (en) |
| AU (1) | AU654208B2 (en) |
| CA (1) | CA2084523C (en) |
| FI (1) | FI940556A (en) |
| IL (1) | IL102613A (en) |
| NO (1) | NO301629B1 (en) |
| NZ (1) | NZ243696A (en) |
| PT (1) | PT100760A (en) |
| TW (1) | TW264392B (en) |
| WO (1) | WO1993002733A1 (en) |
Families Citing this family (166)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US5499975A (en) * | 1989-01-31 | 1996-03-19 | Cook Incorporated | Smooth transitioned dilator-sheath assembly and method |
| FR2697995B1 (en) * | 1992-11-19 | 1994-12-30 | Celsa Lg | Removable blood filtration device, with variable rigidity, implantable in the body of a patient and allowing the injection of a treating product. |
| US5443454A (en) * | 1992-12-09 | 1995-08-22 | Terumo Kabushiki Kaisha | Catheter for embolectomy |
| US5358493A (en) * | 1993-02-18 | 1994-10-25 | Scimed Life Systems, Inc. | Vascular access catheter and methods for manufacture thereof |
| US5538512A (en) * | 1993-02-25 | 1996-07-23 | Zenzon; Wendy J. | Lubricious flow directed catheter |
| US5336205A (en) * | 1993-02-25 | 1994-08-09 | Target Therapeutics, Inc. | Flow directed catheter |
| NL9300728A (en) * | 1993-04-28 | 1994-11-16 | Cordis Europ | Thin-walled catheter with variable properties in a longitudinal direction |
| US5437632A (en) * | 1993-06-02 | 1995-08-01 | Target Therapeutics, Inc. | Variable stiffness balloon catheter |
| JPH0751379A (en) * | 1993-06-24 | 1995-02-28 | Cardiovascular Dynamics Inc | Injection catheter, intravascular site treating method, and production of catheter |
| US5487757A (en) * | 1993-07-20 | 1996-01-30 | Medtronic Cardiorhythm | Multicurve deflectable catheter |
| US5545200A (en) * | 1993-07-20 | 1996-08-13 | Medtronic Cardiorhythm | Steerable electrophysiology catheter |
| NL9301642A (en) * | 1993-09-22 | 1995-04-18 | Cordis Europ | Microcatheter. |
| WO1995013110A1 (en) * | 1993-11-12 | 1995-05-18 | Micro Interventional Systems | Small diameter, high torque catheter |
| US5445624A (en) * | 1994-01-21 | 1995-08-29 | Exonix Research Corporation | Catheter with progressively compliant tip |
| US6858024B1 (en) | 1994-02-14 | 2005-02-22 | Scimed Life Systems, Inc. | Guide catheter having selected flexural modulus segments |
| US5569218A (en) * | 1994-02-14 | 1996-10-29 | Scimed Life Systems, Inc. | Elastic guide catheter transition element |
| US5911715A (en) * | 1994-02-14 | 1999-06-15 | Scimed Life Systems, Inc. | Guide catheter having selected flexural modulus segments |
| KR100186950B1 (en) * | 1994-03-10 | 1999-04-01 | 스피겔 알렌 제이 | Catheter having shaft of verying stiffness |
| US5470322A (en) * | 1994-04-15 | 1995-11-28 | Danforth Biomedical Inc. | Reinforced multilumen catheter for axially varying stiffness |
| US5533985A (en) * | 1994-04-20 | 1996-07-09 | Wang; James C. | Tubing |
| ATE207374T1 (en) | 1994-08-17 | 2001-11-15 | Boston Scient Corp | IMPLANT AND APPLICATION DEVICE |
| US5499973A (en) * | 1994-09-08 | 1996-03-19 | Saab; Mark A. | Variable stiffness balloon dilatation catheters |
| ES2181802T3 (en) * | 1994-11-23 | 2003-03-01 | Micro Interventional Systems I | BALLOON CATHETER WITH STRONG TORSION. |
| US5601538A (en) * | 1995-03-07 | 1997-02-11 | Medtronic, Inc. | Flow directed catheter with hydrophilic distal end |
| US5658263A (en) * | 1995-05-18 | 1997-08-19 | Cordis Corporation | Multisegmented guiding catheter for use in medical catheter systems |
| DK0744163T3 (en) | 1995-05-26 | 2000-04-10 | Schneider Europ Gmbh | Stent expansion system using a pulsating fluid |
| CA2222579A1 (en) * | 1995-06-01 | 1996-12-05 | Scimed Life Systems, Inc. | Flow assisted catheter |
| US5984907A (en) * | 1995-06-05 | 1999-11-16 | Ep Technologies, Inc. | Transition sleeve assembly for catheters |
| WO1997010749A1 (en) * | 1995-09-22 | 1997-03-27 | Guided Medical Systems, Inc. | Catheter shape control by collapsible inner tubular member |
| US5632734A (en) * | 1995-10-10 | 1997-05-27 | Guided Medical Systems, Inc. | Catheter shape control by collapsible inner tubular member |
| US5716321A (en) | 1995-10-10 | 1998-02-10 | Conceptus, Inc. | Method for maintaining separation between a falloposcope and a tubal wall |
| US5951929A (en) * | 1995-12-12 | 1999-09-14 | Medi-Dyne Inc. | Method for forming a catheter having overlapping welds |
| US6103037A (en) * | 1995-12-12 | 2000-08-15 | Medi-Dyne Inc. | Method for making a catheter having overlapping welds |
| US5772641A (en) * | 1995-12-12 | 1998-06-30 | Medi-Dyne Inc. | Overlapping welds for catheter constructions |
| US5836925A (en) * | 1996-04-03 | 1998-11-17 | Soltesz; Peter P. | Catheter with variable flexibility properties and method of manufacture |
| US5899892A (en) * | 1996-05-31 | 1999-05-04 | Scimed Life Systems, Inc. | Catheter having distal fiber braid |
| US5899890A (en) * | 1996-06-21 | 1999-05-04 | Medtronic, Inc. | Flow-directed catheter system and method of use |
| US5820592A (en) * | 1996-07-16 | 1998-10-13 | Hammerslag; Gary R. | Angiographic and/or guide catheter |
| US5826576A (en) * | 1996-08-08 | 1998-10-27 | Medtronic, Inc. | Electrophysiology catheter with multifunction wire and method for making |
| US5899891A (en) * | 1996-09-05 | 1999-05-04 | Epimed International, Inc. | Catheter |
| US5817057A (en) * | 1996-09-13 | 1998-10-06 | Micro Interventional Systems, Inc. | Fluid propulsion steerable catheter and method |
| US6013046A (en) * | 1996-10-16 | 2000-01-11 | Surgin Surgical Instrumentation, Inc. | Sleeve shielded needles for phaco-emulsification devices |
| US5791036A (en) * | 1996-12-23 | 1998-08-11 | Schneider (Usa) Inc | Catheter transition system |
| US6524299B1 (en) | 1997-04-09 | 2003-02-25 | Target Therapeutics, Inc. | Flow-directed catheter |
| US6524296B1 (en) | 1997-04-17 | 2003-02-25 | Medtronic, Inc. | Vessel cannula having properties varying along the axial length |
| US5976120A (en) * | 1997-05-05 | 1999-11-02 | Micro Therapeutics, Inc. | Single segment microcatheter |
| US6030369A (en) * | 1997-07-03 | 2000-02-29 | Target Therapeutics Inc. | Micro catheter shaft |
| WO1999011191A1 (en) | 1997-08-28 | 1999-03-11 | Boston Scientific Corporation | System for implanting a cross-linked polysaccharide fiber and methods of forming and inserting the fiber |
| US6589199B1 (en) | 1997-08-28 | 2003-07-08 | Boston Scientific Corporation | System for implanting a cross-linked polysaccharide fiber and methods of forming and inserting the fiber |
| US6120480A (en) * | 1997-10-28 | 2000-09-19 | Medtronic Ave, Inc. | Catheter introducer |
| US6036682A (en) | 1997-12-02 | 2000-03-14 | Scimed Life Systems, Inc. | Catheter having a plurality of integral radiopaque bands |
| US6240231B1 (en) | 1997-12-22 | 2001-05-29 | Micrus Corporation | Variable stiffness fiber optic shaft |
| US9586023B2 (en) | 1998-02-06 | 2017-03-07 | Boston Scientific Limited | Direct stream hydrodynamic catheter system |
| US7879022B2 (en) | 1998-02-06 | 2011-02-01 | Medrad, Inc. | Rapid exchange fluid jet thrombectomy device and method |
| WO2009117663A2 (en) * | 2008-03-20 | 2009-09-24 | Medrad, Inc. | Direct stream hydrodynamic catheter system |
| AU733053C (en) | 1998-02-24 | 2001-11-29 | Boston Scientific Limited | High flow rate dialysis catheters and related methods |
| US6171296B1 (en) | 1998-04-28 | 2001-01-09 | Microtherapeutics, Inc. | Flow directed catheter |
| US6368316B1 (en) | 1998-06-11 | 2002-04-09 | Target Therapeutics, Inc. | Catheter with composite stiffener |
| US6126650A (en) * | 1998-06-30 | 2000-10-03 | Cordis Corporation | Flow directed catheter having radiopaque strain relief segment |
| US6135111A (en) * | 1998-08-31 | 2000-10-24 | Vital Signs Inc. | Tracheostomy tube with removable inner cannula |
| US6464684B1 (en) | 1998-09-09 | 2002-10-15 | Scimed Life Systems, Inc. | Catheter having regions of differing braid densities and methods of manufacture therefor |
| US6193705B1 (en) | 1998-10-28 | 2001-02-27 | Scimed Life Systems, Inc. | Flow assisted catheter |
| US6322534B1 (en) | 1998-11-07 | 2001-11-27 | Cordis Corporation | Variable stiffness balloon catheter |
| US6197015B1 (en) | 1998-12-09 | 2001-03-06 | Medi-Dyne Inc. | Angiography catheter with sections having different mechanical properties |
| US6165140A (en) | 1998-12-28 | 2000-12-26 | Micrus Corporation | Composite guidewire |
| US6352531B1 (en) | 1999-03-24 | 2002-03-05 | Micrus Corporation | Variable stiffness optical fiber shaft |
| US6887235B2 (en) * | 1999-03-24 | 2005-05-03 | Micrus Corporation | Variable stiffness heating catheter |
| US6355027B1 (en) | 1999-06-09 | 2002-03-12 | Possis Medical, Inc. | Flexible microcatheter |
| US6368315B1 (en) * | 1999-06-23 | 2002-04-09 | Durect Corporation | Composite drug delivery catheter |
| US6500285B2 (en) | 1999-08-23 | 2002-12-31 | Scimed Life Systems, Inc. | Method of making a catheter having interlocking ribbed bond regions |
| US20030032896A1 (en) * | 2000-09-25 | 2003-02-13 | Vance Products, Inc., D/B/A/ Cook Urological, Inc. | Microvolume embryo transfer system |
| US6702802B1 (en) * | 1999-11-10 | 2004-03-09 | Endovascular Technologies, Inc. | Catheters with improved transition |
| US6549812B1 (en) | 1999-11-29 | 2003-04-15 | Medtronic, Inc. | Medical electrical lead having bending stiffness which increase in the distal direction |
| US6556873B1 (en) | 1999-11-29 | 2003-04-29 | Medtronic, Inc. | Medical electrical lead having variable bending stiffness |
| US6524303B1 (en) | 2000-09-08 | 2003-02-25 | Stereotaxis, Inc. | Variable stiffness magnetic catheter |
| US6663614B1 (en) | 2000-11-06 | 2003-12-16 | Advanced Cardiovascular Systems, Inc. | Catheter shaft having variable thickness layers and method of making |
| US6685679B2 (en) | 2000-12-06 | 2004-02-03 | Scimed Life Systems, Inc. | Interlocking metal shaft |
| US6979343B2 (en) * | 2001-02-14 | 2005-12-27 | Ev3 Inc. | Rolled tip recovery catheter |
| US6719804B2 (en) | 2001-04-02 | 2004-04-13 | Scimed Life Systems, Inc. | Medical stent and related methods |
| US7674245B2 (en) | 2001-06-07 | 2010-03-09 | Cardiac Pacemakers, Inc. | Method and apparatus for an adjustable shape guide catheter |
| DE20110121U1 (en) * | 2001-06-19 | 2002-12-05 | Braun Melsungen Ag | catheter |
| US6620202B2 (en) | 2001-10-16 | 2003-09-16 | Scimed Life Systems, Inc. | Medical stent with variable coil and related methods |
| US7018346B2 (en) * | 2001-12-18 | 2006-03-28 | Scimed Life Systems, Inc. | Guide wire with adjustable flexibility |
| US6945970B2 (en) * | 2001-12-27 | 2005-09-20 | Scimed Life Systems, Inc. | Catheter incorporating a curable polymer layer to control flexibility and method of manufacture |
| US7717899B2 (en) | 2002-01-28 | 2010-05-18 | Cardiac Pacemakers, Inc. | Inner and outer telescoping catheter delivery system |
| US20030199852A1 (en) * | 2002-04-23 | 2003-10-23 | Endobionics, Inc. | Attachment joints with polymer encapsulation |
| JP4321019B2 (en) * | 2002-08-01 | 2009-08-26 | 株式会社カネカ | Suction catheter |
| EP1620159B1 (en) * | 2003-04-14 | 2009-08-05 | Cook Incorporated | Large diameter delivery catheter/sheath |
| EP1631185B1 (en) * | 2003-04-22 | 2014-06-18 | Jorge A. Campos | Apparatus for viewing a visually obscured portion of a cavity |
| ATE378085T1 (en) | 2003-04-28 | 2007-11-15 | Cook Inc | FLEXIBLE INTRODUCER WITH DIFFERENT DUROMETER |
| BRPI0410324A (en) | 2003-05-15 | 2006-05-23 | Biomerix Corp | implantable device, elastomeric matrix production lyophilization processes having a cross-linked structure, polymerization for cross-linked elastomeric matrix preparation and cross-linked composite elastomeric implant preparation, and method for treating an orthopedic disorder |
| US7056118B2 (en) * | 2003-05-27 | 2006-06-06 | Ultradent Products, Inc. | Compositions and devices having a tray-like configuration for delivering a medicament and methods of manufacturing and using such compositions and devices |
| US20060129091A1 (en) | 2004-12-10 | 2006-06-15 | Possis Medical, Inc. | Enhanced cross stream mechanical thrombectomy catheter with backloading manifold |
| US7615043B2 (en) * | 2003-08-20 | 2009-11-10 | Boston Scientific Scimed, Inc. | Medical device incorporating a polymer blend |
| US7824392B2 (en) | 2003-08-20 | 2010-11-02 | Boston Scientific Scimed, Inc. | Catheter with thin-walled braid |
| US20050103332A1 (en) * | 2003-11-17 | 2005-05-19 | Bruce Gingles | Airway exchange catheter |
| US8382739B2 (en) | 2003-12-02 | 2013-02-26 | Boston Scientific Scimed, Inc. | Composite medical device and method of forming |
| US7771369B2 (en) * | 2003-12-05 | 2010-08-10 | Boston Scientific Scimed, Inc. | Guide catheter with removable support |
| US7273487B1 (en) | 2003-12-18 | 2007-09-25 | Advanced Cardiovascular Systems, Inc. | Balloon catheter having a multilayered shaft with variable flexibility |
| US7763077B2 (en) | 2003-12-24 | 2010-07-27 | Biomerix Corporation | Repair of spinal annular defects and annulo-nucleoplasty regeneration |
| US20050149176A1 (en) * | 2003-12-29 | 2005-07-07 | Scimed Life Systems, Inc. | Selectively light curable support members for medical devices |
| US7601285B2 (en) * | 2003-12-31 | 2009-10-13 | Boston Scientific Scimed, Inc. | Medical device with varying physical properties and method for forming same |
| EP1715827B1 (en) * | 2004-01-23 | 2010-12-29 | iScience Interventional Corporation | Composite ophthalmic microcannula |
| US7572244B2 (en) | 2004-08-02 | 2009-08-11 | Medrad, Inc. | Miniature cross stream thrombectomy catheter |
| US8475402B2 (en) * | 2004-09-16 | 2013-07-02 | Data, LLC | Aspiration system for medical devices |
| US20060111649A1 (en) * | 2004-11-19 | 2006-05-25 | Scimed Life Systems, Inc. | Catheter having improved torque response and curve retention |
| US8771294B2 (en) | 2004-11-26 | 2014-07-08 | Biomerix Corporation | Aneurysm treatment devices and methods |
| US7828790B2 (en) * | 2004-12-03 | 2010-11-09 | Boston Scientific Scimed, Inc. | Selectively flexible catheter and method of use |
| US7828832B2 (en) * | 2005-04-18 | 2010-11-09 | Medtronic Vascular, Inc. | Intravascular deployment device with improved deployment capability |
| US20060270976A1 (en) * | 2005-05-31 | 2006-11-30 | Prorhythm, Inc. | Steerable catheter |
| US7695466B2 (en) * | 2005-07-14 | 2010-04-13 | Beisel Robert F | Stylet free flexible-tip epidural catheter and method of making |
| US20080188793A1 (en) | 2007-02-06 | 2008-08-07 | Possis Medical, Inc. | Miniature flexible thrombectomy catheter |
| US8012117B2 (en) * | 2007-02-06 | 2011-09-06 | Medrad, Inc. | Miniature flexible thrombectomy catheter |
| US8162878B2 (en) * | 2005-12-05 | 2012-04-24 | Medrad, Inc. | Exhaust-pressure-operated balloon catheter system |
| US8007434B2 (en) * | 2006-03-06 | 2011-08-30 | Boston Scientific Scimed, Inc. | Variable stiffness medical device shaft |
| US8303569B2 (en) * | 2006-04-19 | 2012-11-06 | Medtronic Vascular, Inc. | Composite laminated catheter with flexible segment and method of making same |
| US8308712B2 (en) * | 2006-04-19 | 2012-11-13 | Medronic Vascular, Inc. | Composite laminated catheter with flexible segment and method of making same |
| US7905877B1 (en) | 2006-05-12 | 2011-03-15 | Micrus Design Technology, Inc. | Double helix reinforced catheter |
| US20080125752A1 (en) * | 2006-08-09 | 2008-05-29 | Boston Scientific Scimed, Inc. | Catheter assembly having a modified reinforcement layer |
| US8974418B2 (en) * | 2007-06-12 | 2015-03-10 | Boston Scientific Limited | Forwardly directed fluid jet crossing catheter |
| US20080319386A1 (en) * | 2007-06-20 | 2008-12-25 | Possis Medical, Inc. | Forwardly directable fluid jet crossing catheter |
| US9510885B2 (en) | 2007-11-16 | 2016-12-06 | Osseon Llc | Steerable and curvable cavity creation system |
| US20090131886A1 (en) | 2007-11-16 | 2009-05-21 | Liu Y King | Steerable vertebroplasty system |
| US20090131867A1 (en) | 2007-11-16 | 2009-05-21 | Liu Y King | Steerable vertebroplasty system with cavity creation element |
| US8403885B2 (en) * | 2007-12-17 | 2013-03-26 | Abbott Cardiovascular Systems Inc. | Catheter having transitioning shaft segments |
| WO2009079539A1 (en) * | 2007-12-17 | 2009-06-25 | Medrad, Inc. | Rheolytic thrombectomy catheter with self-inflation distal balloon |
| US8439878B2 (en) | 2007-12-26 | 2013-05-14 | Medrad, Inc. | Rheolytic thrombectomy catheter with self-inflating proximal balloon with drug infusion capabilities |
| WO2009082723A1 (en) * | 2007-12-26 | 2009-07-02 | Cook Incorporated | Deployment catheter |
| US8684999B2 (en) * | 2007-12-31 | 2014-04-01 | St. Jude Medical, Atrial Fibrillation Division, Inc. | Catheter shaft and method of manufacture |
| ATE529151T1 (en) * | 2008-06-16 | 2011-11-15 | Greatbatch Ltd | BIDIRECTIONAL ASYMMETRIC STEERING SHELL |
| US20100168642A1 (en) * | 2008-12-30 | 2010-07-01 | Angiodynamics, Inc. | Multilumen Venous Catheter and Method of Use |
| US9265907B2 (en) * | 2008-12-30 | 2016-02-23 | Cook Medical Technologies Llc | Self-centering tracheostomy tube |
| US8725228B2 (en) * | 2009-02-20 | 2014-05-13 | Boston Scientific Scimed, Inc. | Steerable catheter having intermediate stiffness transition zone |
| US8478423B2 (en) * | 2009-04-07 | 2013-07-02 | Boston Scientific Neuromodulation Corporation | Insulator layers for leads of implantable electric stimulation systems and methods of making and using |
| US20100298832A1 (en) | 2009-05-20 | 2010-11-25 | Osseon Therapeutics, Inc. | Steerable curvable vertebroplasty drill |
| DE102009023661A1 (en) * | 2009-06-03 | 2010-12-16 | Acandis Gmbh & Co. Kg | Medical catheter, medical functional element and arrangement comprising such a catheter and such a functional element |
| US8340782B2 (en) | 2009-07-08 | 2012-12-25 | Boston Scientific Neuromodulation Corporation | Systems and methods of making and using support elements for elongated members of implantable electric stimulation systems |
| US8406897B2 (en) * | 2009-08-19 | 2013-03-26 | Boston Scientific Neuromodulation Corporation | Systems and methods for disposing one or more layers of material between lead conductor segments of electrical stimulation systems |
| US20120238806A1 (en) * | 2009-08-24 | 2012-09-20 | Quali-Med Gmbh | Implantation system with handle and catheter and method of use thereof |
| US9387035B2 (en) * | 2009-08-25 | 2016-07-12 | Medtronic Ablation Frontiers Llc | Bi-modal catheter steering mechanism |
| US9439721B2 (en) * | 2009-08-25 | 2016-09-13 | Medtronic Ablation Frontiers Llc | Bi-modal linear and loop ablation catheter, and method |
| GB2474253A (en) | 2009-10-08 | 2011-04-13 | Surgical Innovations Ltd | Flexible endoscope controllable between extended and crossed configurations |
| US8579802B2 (en) * | 2009-11-02 | 2013-11-12 | Boston Scientific Scimed, Inc. | Flexible endoscope with modifiable stiffness |
| CA2726418A1 (en) * | 2010-01-12 | 2011-07-12 | Custom Medical Applications, Inc. | Ultrasound guided echogenic catheter and related methods |
| GB201003516D0 (en) | 2010-03-03 | 2010-04-21 | Surgical Innovations Ltd | Instruments |
| WO2011137377A1 (en) | 2010-04-29 | 2011-11-03 | Dfine, Inc. | System for use in treatment of vertebral fractures |
| ES2856026T3 (en) * | 2010-05-03 | 2021-09-27 | Neuwave Medical Inc | Power supply systems |
| US9744349B2 (en) * | 2011-02-10 | 2017-08-29 | Respicardia, Inc. | Medical lead and implantation |
| EP2682151A1 (en) * | 2012-07-06 | 2014-01-08 | Sorin CRM SAS | Implantable microcatheter into venous, arterial and lymphatic system |
| EP2910272B1 (en) | 2014-02-19 | 2020-11-04 | Willy Rüsch GmbH | Foldable urinary catheter |
| DK3247417T3 (en) | 2015-01-22 | 2021-04-26 | Hollister Inc | URINARY CATHETER WITH LUBRICATION PROPERTIES AND VARIOUS FLEXIBILITY |
| US9827122B2 (en) | 2015-05-04 | 2017-11-28 | Abbott Cardiovascular Systems Inc. | System for a catheter |
| KR101644551B1 (en) * | 2015-05-11 | 2016-08-03 | 전남대학교산학협력단 | Guidewire and guidewire system |
| US10357631B2 (en) | 2015-05-29 | 2019-07-23 | Covidien Lp | Catheter with tapering outer diameter |
| US10398874B2 (en) | 2015-05-29 | 2019-09-03 | Covidien Lp | Catheter distal tip configuration |
| US11219740B2 (en) | 2015-05-29 | 2022-01-11 | Covidien Lp | Catheter including tapering coil member |
| JP6886471B2 (en) * | 2016-09-05 | 2021-06-16 | テルモ株式会社 | catheter |
| JP2019534130A (en) | 2016-10-27 | 2019-11-28 | ディーファイン，インコーポレイティド | Articulated osteotome with cement delivery channel |
| US11116570B2 (en) | 2016-11-28 | 2021-09-14 | Dfine, Inc. | Tumor ablation devices and related methods |
| WO2018107036A1 (en) | 2016-12-09 | 2018-06-14 | Dfine, Inc. | Medical devices for treating hard tissues and related methods |
| WO2018129180A1 (en) | 2017-01-06 | 2018-07-12 | Dfine, Inc. | Osteotome with a distal portion for simultaneous advancement and articulation |
| US10926060B2 (en) | 2017-03-02 | 2021-02-23 | Covidien Lp | Flexible tip catheter |
| US10537710B2 (en) | 2017-04-20 | 2020-01-21 | Covidien Lp | Catheter including an inner liner with a flexible distal section |
| EP3876856A4 (en) | 2018-11-08 | 2022-10-12 | Dfine, Inc. | Tumor ablation device and related systems and methods |
| EP4022674A2 (en) | 2019-08-26 | 2022-07-06 | X-Celeprint Limited | Variable stiffness modules |
| US11801087B2 (en) * | 2019-11-13 | 2023-10-31 | Boston Scientific Medical Device Limited | Apparatus and methods for puncturing tissue |
Family Cites Families (20)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US3895078A (en) * | 1972-04-27 | 1975-07-15 | Us Agriculture | Boll-weevil sex attractant |
| US4282876A (en) * | 1979-05-18 | 1981-08-11 | Flynn Vincent J | Radiopaque polyurethane resin compositions |
| US4690175A (en) * | 1981-11-17 | 1987-09-01 | Kabushiki Kaisha Medos Kenkyusho | Flexible tube for endoscope |
| JPS5886129A (en) * | 1981-11-17 | 1983-05-23 | 旭光学工業株式会社 | Flexible tube of endoscope and production thereof |
| US4596563A (en) * | 1983-06-09 | 1986-06-24 | Cordis Corporation | Thin-walled multi-layered catheter having a fuseless tip |
| US4531943A (en) * | 1983-08-08 | 1985-07-30 | Angiomedics Corporation | Catheter with soft deformable tip |
| US4573476A (en) * | 1983-11-14 | 1986-03-04 | Ruiz Oscar F | Angiographic catheter |
| US4636346A (en) * | 1984-03-08 | 1987-01-13 | Cordis Corporation | Preparing guiding catheter |
| US4846814A (en) * | 1986-01-16 | 1989-07-11 | Sherwood Medical Company | Non-whip catheter |
| US4739768B2 (en) * | 1986-06-02 | 1995-10-24 | Target Therapeutics Inc | Catheter for guide-wire tracking |
| US4775371A (en) * | 1986-09-02 | 1988-10-04 | Advanced Cardiovascular Systems, Inc. | Stiffened dilatation catheter and method of manufacture |
| US4863442A (en) * | 1987-08-14 | 1989-09-05 | C. R. Bard, Inc. | Soft tip catheter |
| US4925663A (en) * | 1987-12-31 | 1990-05-15 | University Of Florida | Biological control of imported fire ants with a fungal pathogen |
| US5078702A (en) * | 1988-03-25 | 1992-01-07 | Baxter International Inc. | Soft tip catheters |
| US4961731A (en) * | 1988-06-09 | 1990-10-09 | Sherwood Medical Company | Angiographic catheter with balanced dye injection openings |
| US4898591A (en) * | 1988-08-09 | 1990-02-06 | Mallinckrodt, Inc. | Nylon-PEBA copolymer catheter |
| US5069662A (en) * | 1988-10-21 | 1991-12-03 | Delcath Systems, Inc. | Cancer treatment |
| US4908977A (en) * | 1989-01-13 | 1990-03-20 | E. I. Du Pont De Nemours And Company | Device for killing arthropods |
| US4955862A (en) * | 1989-05-22 | 1990-09-11 | Target Therapeutics, Inc. | Catheter and catheter/guide wire device |
| US5085649A (en) * | 1990-11-21 | 1992-02-04 | Flynn Vincent J | Torque controlled tubing |
-
1991
- 1991-08-07 US US07/741,775 patent/US5308342A/en not_active Expired - Lifetime
-
1992
- 1992-07-23 IL IL10261392A patent/IL102613A/en not_active IP Right Cessation
- 1992-07-23 NZ NZ243696A patent/NZ243696A/en unknown
- 1992-08-03 CA CA002084523A patent/CA2084523C/en not_active Expired - Fee Related
- 1992-08-03 JP JP5503778A patent/JP2589943B2/en not_active Expired - Lifetime
- 1992-08-03 WO PCT/US1992/006422 patent/WO1993002733A1/en not_active Application Discontinuation
- 1992-08-03 EP EP19920917700 patent/EP0598025A4/en not_active Ceased
- 1992-08-03 AU AU24066/92A patent/AU654208B2/en not_active Ceased
- 1992-08-04 PT PT100760A patent/PT100760A/en not_active Application Discontinuation
-
1993
- 1993-01-27 TW TW082100503A patent/TW264392B/zh active
-
1994
- 1994-01-27 NO NO940296A patent/NO301629B1/en unknown
- 1994-02-07 FI FI940556A patent/FI940556A/en unknown
Also Published As
| Publication number | Publication date |
|---|---|
| AU2406692A (en) | 1993-03-02 |
| AU654208B2 (en) | 1994-10-27 |
| CA2084523A1 (en) | 1993-02-08 |
| IL102613A0 (en) | 1993-01-14 |
| JP2589943B2 (en) | 1997-03-12 |
| NO940296D0 (en) | 1994-01-27 |
| TW264392B (en) | 1995-12-01 |
| FI940556A0 (en) | 1994-02-07 |
| FI940556A (en) | 1994-02-07 |
| NO301629B1 (en) | 1997-11-24 |
| WO1993002733A1 (en) | 1993-02-18 |
| NO940296L (en) | 1994-01-27 |
| IL102613A (en) | 1996-01-31 |
| NZ243696A (en) | 1995-04-27 |
| EP0598025A1 (en) | 1994-05-25 |
| EP0598025A4 (en) | 1994-07-20 |
| JPH06507566A (en) | 1994-09-01 |
| PT100760A (en) | 1994-05-31 |
| US5308342A (en) | 1994-05-03 |
Similar Documents
| Publication | Publication Date | Title |
|---|---|---|
| CA2084523C (en) | Variable stiffness catheter | |
| US5437632A (en) | Variable stiffness balloon catheter | |
| EP0715863B1 (en) | Catheter | |
| CA2170913C (en) | Kink-free spiral-wound catheter | |
| US5782809A (en) | Vascular catheter | |
| US4739768A (en) | Catheter for guide-wire tracking | |
| US5951539A (en) | Optimized high performance multiple coil spiral-wound vascular catheter | |
| US5599326A (en) | Catheter with multi-layer section | |
| US6258080B1 (en) | Kink-free spiral-wound catheter | |
| US6398776B1 (en) | Tubular medical device | |
| US20040236215A1 (en) | Catheter | |
| JPH08508928A (en) | Catheter with kink-resistant distal tip |
Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| EEER | Examination request | ||
| MKLA | Lapsed |