CA2101637A1 - Collagen-based adhesives, methods of preparation and potential use - Google Patents

Collagen-based adhesives, methods of preparation and potential use

Info

Publication number
CA2101637A1
CA2101637A1 CA002101637A CA2101637A CA2101637A1 CA 2101637 A1 CA2101637 A1 CA 2101637A1 CA 002101637 A CA002101637 A CA 002101637A CA 2101637 A CA2101637 A CA 2101637A CA 2101637 A1 CA2101637 A1 CA 2101637A1
Authority
CA
Canada
Prior art keywords
collagen
preparation
medical
methods
based adhesives
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Granted
Application number
CA002101637A
Other languages
French (fr)
Other versions
CA2101637C (en
Inventor
CHARLES D. kELMAN
Dale P. Devore
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
CR Bard Inc
Original Assignee
Individual
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Individual filed Critical Individual
Publication of CA2101637A1 publication Critical patent/CA2101637A1/en
Application granted granted Critical
Publication of CA2101637C publication Critical patent/CA2101637C/en
Anticipated expiration legal-status Critical
Expired - Fee Related legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C08—ORGANIC MACROMOLECULAR COMPOUNDS; THEIR PREPARATION OR CHEMICAL WORKING-UP; COMPOSITIONS BASED THEREON
    • C08H—DERIVATIVES OF NATURAL MACROMOLECULAR COMPOUNDS
    • C08H1/00—Macromolecular products derived from proteins
    • C08H1/06—Macromolecular products derived from proteins derived from horn, hoofs, hair, skin or leather
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
    • A61L24/00—Surgical adhesives or cements; Adhesives for colostomy devices
    • A61L24/04—Surgical adhesives or cements; Adhesives for colostomy devices containing macromolecular materials
    • A61L24/10—Polypeptides; Proteins
    • A61L24/102—Collagen
    • C—CHEMISTRY; METALLURGY
    • C09—DYES; PAINTS; POLISHES; NATURAL RESINS; ADHESIVES; COMPOSITIONS NOT OTHERWISE PROVIDED FOR; APPLICATIONS OF MATERIALS NOT OTHERWISE PROVIDED FOR
    • C09J—ADHESIVES; NON-MECHANICAL ASPECTS OF ADHESIVE PROCESSES IN GENERAL; ADHESIVE PROCESSES NOT PROVIDED FOR ELSEWHERE; USE OF MATERIALS AS ADHESIVES
    • C09J189/00—Adhesives based on proteins; Adhesives based on derivatives thereof
    • C09J189/04—Products derived from waste materials, e.g. horn, hoof or hair
    • C09J189/06—Products derived from waste materials, e.g. horn, hoof or hair derived from leather or skin
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61F—FILTERS IMPLANTABLE INTO BLOOD VESSELS; PROSTHESES; DEVICES PROVIDING PATENCY TO, OR PREVENTING COLLAPSING OF, TUBULAR STRUCTURES OF THE BODY, e.g. STENTS; ORTHOPAEDIC, NURSING OR CONTRACEPTIVE DEVICES; FOMENTATION; TREATMENT OR PROTECTION OF EYES OR EARS; BANDAGES, DRESSINGS OR ABSORBENT PADS; FIRST-AID KITS
    • A61F9/00—Methods or devices for treatment of the eyes; Devices for putting-in contact lenses; Devices to correct squinting; Apparatus to guide the blind; Protective devices for the eyes, carried on the body or in the hand
    • A61F9/007—Methods or devices for eye surgery
    • A61F9/0079—Methods or devices for eye surgery using non-laser electromagnetic radiation, e.g. non-coherent light or microwaves
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61F—FILTERS IMPLANTABLE INTO BLOOD VESSELS; PROSTHESES; DEVICES PROVIDING PATENCY TO, OR PREVENTING COLLAPSING OF, TUBULAR STRUCTURES OF THE BODY, e.g. STENTS; ORTHOPAEDIC, NURSING OR CONTRACEPTIVE DEVICES; FOMENTATION; TREATMENT OR PROTECTION OF EYES OR EARS; BANDAGES, DRESSINGS OR ABSORBENT PADS; FIRST-AID KITS
    • A61F9/00—Methods or devices for treatment of the eyes; Devices for putting-in contact lenses; Devices to correct squinting; Apparatus to guide the blind; Protective devices for the eyes, carried on the body or in the hand
    • A61F9/007—Methods or devices for eye surgery
    • A61F9/008—Methods or devices for eye surgery using laser
    • A61F9/00802—Methods or devices for eye surgery using laser for photoablation
    • A61F9/00817—Beam shaping with masks
    • A61F9/00819—Beam shaping with masks with photoablatable masks

Abstract

Collagen-based compositions as adhesives and sealants for medical use and preparation thereof are described. Prior to po-lymerization, soluble or partially fibrillar collagen monomers in solution are chemically modified with an acylating agent, sulfo-nating agent or a combination of the foregoing. The collagen compositions prepared accordingly can be used as medical adhe-sives for bonding soft tissues or be made in to a sealant film for a variety of medical uses such as wound closures and tendon wraps for preventing adhesion formation following surgery.
CA002101637A 1991-01-29 1992-01-27 Collagen-based adhesives, methods of preparation and potential use Expired - Fee Related CA2101637C (en)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US646,944 1991-01-29
US07/646,944 US5219895A (en) 1991-01-29 1991-01-29 Collagen-based adhesives and sealants and methods of preparation and use thereof
PCT/US1992/000704 WO1992013025A1 (en) 1991-01-29 1992-01-27 Collagen-based adhesives and sealants and methods of preparation thereof

Publications (2)

Publication Number Publication Date
CA2101637A1 true CA2101637A1 (en) 1992-07-30
CA2101637C CA2101637C (en) 2003-08-19

Family

ID=24595097

Family Applications (1)

Application Number Title Priority Date Filing Date
CA002101637A Expired - Fee Related CA2101637C (en) 1991-01-29 1992-01-27 Collagen-based adhesives, methods of preparation and potential use

Country Status (5)

Country Link
US (3) US5219895A (en)
EP (1) EP0569551B1 (en)
CA (1) CA2101637C (en)
DE (1) DE69232835D1 (en)
WO (1) WO1992013025A1 (en)

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US5219895A (en) 1993-06-15
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CA2101637C (en) 2003-08-19
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DE69232835D1 (en) 2002-12-05
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EP0569551B1 (en) 2002-10-30
EP0569551A1 (en) 1993-11-18

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