CA2108249A1 - Intramedullary nail - Google Patents
Intramedullary nailInfo
- Publication number
- CA2108249A1 CA2108249A1 CA002108249A CA2108249A CA2108249A1 CA 2108249 A1 CA2108249 A1 CA 2108249A1 CA 002108249 A CA002108249 A CA 002108249A CA 2108249 A CA2108249 A CA 2108249A CA 2108249 A1 CA2108249 A1 CA 2108249A1
- Authority
- CA
- Canada
- Prior art keywords
- nail
- insert
- medullar
- end region
- fact
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Abandoned
Links
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
- A61B17/00—Surgical instruments, devices or methods, e.g. tourniquets
- A61B17/56—Surgical instruments or methods for treatment of bones or joints; Devices specially adapted therefor
- A61B17/58—Surgical instruments or methods for treatment of bones or joints; Devices specially adapted therefor for osteosynthesis, e.g. bone plates, screws, setting implements or the like
- A61B17/68—Internal fixation devices, including fasteners and spinal fixators, even if a part thereof projects from the skin
- A61B17/72—Intramedullary pins, nails or other devices
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
- A61B17/00—Surgical instruments, devices or methods, e.g. tourniquets
- A61B17/56—Surgical instruments or methods for treatment of bones or joints; Devices specially adapted therefor
- A61B17/58—Surgical instruments or methods for treatment of bones or joints; Devices specially adapted therefor for osteosynthesis, e.g. bone plates, screws, setting implements or the like
- A61B17/68—Internal fixation devices, including fasteners and spinal fixators, even if a part thereof projects from the skin
- A61B17/72—Intramedullary pins, nails or other devices
- A61B17/7233—Intramedullary pins, nails or other devices with special means of locking the nail to the bone
- A61B17/7241—Intramedullary pins, nails or other devices with special means of locking the nail to the bone the nail having separate elements through which screws pass
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
- A61B17/00—Surgical instruments, devices or methods, e.g. tourniquets
- A61B2017/00004—(bio)absorbable, (bio)resorbable, resorptive
Abstract
Abstract The present invention relates to a medullar nail having a plug-like insert arranged in the end region of the metal nail, said insert consisting of a readily drillable or screwable material and being suitable for receiving a corresponding attachment element such as a bone screw or a bone pin.
Description
TRANS LATION
ro~11 2 1 0 8 2 4 9 Medullar Nail The present invention relates to a medullar nail.
While it is no problem in the case of lower arm and femur nails to securely hold these nails in their associated bone sections by attachment screws which extend transverse to the longitudinal axis of the nail, in the case of a humerus - nail (DE 88 11 634 Ul), there is the danger that by drilling the required holes for the attachment screws, nerves may be injured so that a secure fixing in position of a humerus nail has not been possible up to now.
It is, therefore, the object of the present invention to provide a medullar nail with whicb it is possible to dispense with drilling through the cortex on both sides of the nail, i.e. the nail i6 fixed in position only on one side by an attachment pin or a corresponding screw driven into the cortex and the nail.
i This object of the invention is achieved in accordance with the invention by a plug-like insert which iR arranged in the end region of the metal nail and which is directed transverse to the longitudinal axis of the nail, said insert debouching towards the outside at least on one side of the nail and consisting of a material which can readily be ~;
drilled, or into which a screw can readily be screwed.
By this measure, it is now possible to drill through the cortex of the humerus only on one side and to introduce ~;~ through said hole a screw or a pin which at one end is held `~ LAWYERS' AND MERCHANTS' TRANSLATION BUREAU INC.
'~ Lc~al. Financ;AI. Scientific. T~chnical and Patem Translations Tcl: ~212)144 293n/2931 11 BROADWAY. NEW YORK. NY 10004 Faa: (2121 42'-6R77 . :.
~, ~ Consullant Founded in 1903 hy , WM, BERTSCHE. J.D., CH.E.. A.C.S. CARL V, BERTSCHE
:~ ' TRANSLATION 2 l;,Qg 2 ~ 9 rom.
_ securely in the cortex but engages at the other end lnto the insert within the nail without protruding on the other side out of the nail. In this way, an injuring or damaging of the sensitive nerves on the other side is reliably excluded.
It is provided in accordance with the invention that the insert be arranged in one or more blind holes or in cylindrical holes which are cylindrical over a large part of - their length but then taper conically so that, upon the insertion of the material into said hole, no cavities can be created by inclusions of air or the like.
The insert can consist of plastic, but it can also advantageously be made of a material which is biodegradable, the period for such biological degradation being, of course, longer than is required for healing a fracture of the humerus so that the nail can be removed again in due time. By using the biodegradable material, the result is, however, achieved that splinters of material produced upon the drilling cannot lead to inflammations or the like.
one embodiment of the invention will be explained below with reference to the drawing.
~ The drawing shows a part of a nail 1 in the one end ;~; region of which there is provided an insert 2 which, in the .~- embodiment shown, is arranged in a cylindrical hole developed a~ blind hole. This insert consists of a biodegradable ~; material. After drilling through the cortex, a screw can now be screwed into said insert which in this end region of the 3~
`~1 ~ LAU~ERS'AND MERCHANTS~TRANSLATION BUREAUINC.
~' Le~al, Financial, Scientirlc, Technical and Pat~nl Translalions Tcl: (212)344-293il/2931 11 BROADWAY,NEWYORK,NY 10004 Fa~: (212)42'6#77 . 1 Consullanl Found~d in 191)3 hy 1~ WM. 13ERTSCHE. J.D.. CH.E., A.C.S. CARL V, 13ERTSCHE
~A . .
~A . . , . ~ ~
!
, , , , , . . .. . ~ . ... . .. . . .
ro~11 2 1 0 8 2 4 9 Medullar Nail The present invention relates to a medullar nail.
While it is no problem in the case of lower arm and femur nails to securely hold these nails in their associated bone sections by attachment screws which extend transverse to the longitudinal axis of the nail, in the case of a humerus - nail (DE 88 11 634 Ul), there is the danger that by drilling the required holes for the attachment screws, nerves may be injured so that a secure fixing in position of a humerus nail has not been possible up to now.
It is, therefore, the object of the present invention to provide a medullar nail with whicb it is possible to dispense with drilling through the cortex on both sides of the nail, i.e. the nail i6 fixed in position only on one side by an attachment pin or a corresponding screw driven into the cortex and the nail.
i This object of the invention is achieved in accordance with the invention by a plug-like insert which iR arranged in the end region of the metal nail and which is directed transverse to the longitudinal axis of the nail, said insert debouching towards the outside at least on one side of the nail and consisting of a material which can readily be ~;
drilled, or into which a screw can readily be screwed.
By this measure, it is now possible to drill through the cortex of the humerus only on one side and to introduce ~;~ through said hole a screw or a pin which at one end is held `~ LAWYERS' AND MERCHANTS' TRANSLATION BUREAU INC.
'~ Lc~al. Financ;AI. Scientific. T~chnical and Patem Translations Tcl: ~212)144 293n/2931 11 BROADWAY. NEW YORK. NY 10004 Faa: (2121 42'-6R77 . :.
~, ~ Consullant Founded in 1903 hy , WM, BERTSCHE. J.D., CH.E.. A.C.S. CARL V, BERTSCHE
:~ ' TRANSLATION 2 l;,Qg 2 ~ 9 rom.
_ securely in the cortex but engages at the other end lnto the insert within the nail without protruding on the other side out of the nail. In this way, an injuring or damaging of the sensitive nerves on the other side is reliably excluded.
It is provided in accordance with the invention that the insert be arranged in one or more blind holes or in cylindrical holes which are cylindrical over a large part of - their length but then taper conically so that, upon the insertion of the material into said hole, no cavities can be created by inclusions of air or the like.
The insert can consist of plastic, but it can also advantageously be made of a material which is biodegradable, the period for such biological degradation being, of course, longer than is required for healing a fracture of the humerus so that the nail can be removed again in due time. By using the biodegradable material, the result is, however, achieved that splinters of material produced upon the drilling cannot lead to inflammations or the like.
one embodiment of the invention will be explained below with reference to the drawing.
~ The drawing shows a part of a nail 1 in the one end ;~; region of which there is provided an insert 2 which, in the .~- embodiment shown, is arranged in a cylindrical hole developed a~ blind hole. This insert consists of a biodegradable ~; material. After drilling through the cortex, a screw can now be screwed into said insert which in this end region of the 3~
`~1 ~ LAU~ERS'AND MERCHANTS~TRANSLATION BUREAUINC.
~' Le~al, Financial, Scientirlc, Technical and Pat~nl Translalions Tcl: (212)344-293il/2931 11 BROADWAY,NEWYORK,NY 10004 Fa~: (212)42'6#77 . 1 Consullanl Found~d in 191)3 hy 1~ WM. 13ERTSCHE. J.D.. CH.E., A.C.S. CARL V, 13ERTSCHE
~A . .
~A . . , . ~ ~
!
, , , , , . . .. . ~ . ... . .. . . .
2~Q~24~
fron~. ' nail results in a fixing in position of the nail on the cortex.
-~ LAWYERS' AND MERCHANTS' TRANSLATION BUREAU INC.
Lc81l1, Financial ScienRfic T~chnical and Pa~en~ T~anslalions , ~ Tel: ~212~ 34~-2930/2931 11 E3ROADWAY NEW YORK, NY 10(104 Fox~ 4~ 177 Con~uhanl Fo~lndcd in 190? hy WM. nEP~l-S~'llE. J.l).. CH.E.. A.C.S. CARL V, nERTS~'III:
,~
~' , , :~ :
: : ' , ~ .
~ . . .
fron~. ' nail results in a fixing in position of the nail on the cortex.
-~ LAWYERS' AND MERCHANTS' TRANSLATION BUREAU INC.
Lc81l1, Financial ScienRfic T~chnical and Pa~en~ T~anslalions , ~ Tel: ~212~ 34~-2930/2931 11 E3ROADWAY NEW YORK, NY 10(104 Fox~ 4~ 177 Con~uhanl Fo~lndcd in 190? hy WM. nEP~l-S~'llE. J.l).. CH.E.. A.C.S. CARL V, nERTS~'III:
,~
~' , , :~ :
: : ' , ~ .
~ . . .
Claims (4)
1. A medullar nail, characterized by a plug-like insert (2) which is arranged in the end region of the metal nail (1) and extends transverse to the longitudinal axis of the nail, said insert (2) debouching towards the outside at least on one side of the nail and consisting of a material which can be readily drilled or into which a screw can readily be screwed.
2. A medullar nail according to Claim 1, characterized by the fact that the insert (2) consists of a biodegradable material.
3. A medullar nail according to Claim 1 or 2, characterized by the fact that the insert (2) is arranged in one or more blind holes in the nail (1).
4. A medullar nail according to Claim 1 or 2, characterized by the fact that the insert (2) is arranged in a cylindrical hole which, in its end region, tapers conically towards the other side of the nail.
Applications Claiming Priority (4)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
DE4204246 | 1992-02-13 | ||
DEP4204246.1 | 1992-02-13 | ||
DEP4205118.5 | 1992-02-20 | ||
DE4205118A DE4205118C1 (en) | 1992-02-13 | 1992-02-20 |
Publications (1)
Publication Number | Publication Date |
---|---|
CA2108249A1 true CA2108249A1 (en) | 1993-08-14 |
Family
ID=25911805
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
CA002108249A Abandoned CA2108249A1 (en) | 1992-02-13 | 1993-02-11 | Intramedullary nail |
Country Status (8)
Country | Link |
---|---|
US (1) | US5484438A (en) |
EP (1) | EP0583442B1 (en) |
JP (1) | JPH06507104A (en) |
AT (1) | ATE143787T1 (en) |
CA (1) | CA2108249A1 (en) |
DE (2) | DE4205118C1 (en) |
ES (1) | ES2093405T3 (en) |
WO (1) | WO1993015679A1 (en) |
Families Citing this family (60)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
DE19751284A1 (en) | 1997-11-19 | 1999-05-27 | Leo Prof Dr Gotzen | Fixation element |
US5935127A (en) * | 1997-12-17 | 1999-08-10 | Biomet, Inc. | Apparatus and method for treatment of a fracture in a long bone |
US6019761A (en) * | 1998-12-23 | 2000-02-01 | Gustilo; Ramon B. | Intramedullary nail and method of use |
US6296645B1 (en) | 1999-04-09 | 2001-10-02 | Depuy Orthopaedics, Inc. | Intramedullary nail with non-metal spacers |
US6783529B2 (en) | 1999-04-09 | 2004-08-31 | Depuy Orthopaedics, Inc. | Non-metal inserts for bone support assembly |
US5983904A (en) * | 1999-05-20 | 1999-11-16 | Conair Corporation | Hair curler |
US7008425B2 (en) * | 1999-05-27 | 2006-03-07 | Jonathan Phillips | Pediatric intramedullary nail and method |
US6520996B1 (en) * | 1999-06-04 | 2003-02-18 | Depuy Acromed, Incorporated | Orthopedic implant |
US6893444B2 (en) * | 2000-02-01 | 2005-05-17 | Hand Innovations, Llc | Bone fracture fixation systems with both multidirectional and unidirectional stabilization pegs |
US20060041260A1 (en) * | 2000-02-01 | 2006-02-23 | Orbay Jorge L | Fixation system with plate having holes with divergent axes and multidirectional fixators for use therethrough |
US7695502B2 (en) | 2000-02-01 | 2010-04-13 | Depuy Products, Inc. | Bone stabilization system including plate having fixed-angle holes together with unidirectional locking screws and surgeon-directed locking screws |
US7857838B2 (en) | 2003-03-27 | 2010-12-28 | Depuy Products, Inc. | Anatomical distal radius fracture fixation plate |
US6767351B2 (en) * | 2000-02-01 | 2004-07-27 | Hand Innovations, Inc. | Fixation system with multidirectional stabilization pegs |
US6706046B2 (en) * | 2000-02-01 | 2004-03-16 | Hand Innovations, Inc. | Intramedullary fixation device for metaphyseal long bone fractures and methods of using the same |
US20040153073A1 (en) | 2000-02-01 | 2004-08-05 | Hand Innovations, Inc. | Orthopedic fixation system including plate element with threaded holes having divergent axes |
US6730090B2 (en) | 2000-02-01 | 2004-05-04 | Hand Innovations, Inc. | Fixation device for metaphyseal long bone fractures |
US6808527B2 (en) | 2000-04-10 | 2004-10-26 | Depuy Orthopaedics, Inc. | Intramedullary nail with snap-in window insert |
US6527775B1 (en) * | 2000-09-22 | 2003-03-04 | Piper Medical, Inc. | Intramedullary interlocking fixation device for the distal radius |
US20060149257A1 (en) * | 2002-05-30 | 2006-07-06 | Orbay Jorge L | Fracture fixation device |
US7938850B2 (en) * | 2002-05-30 | 2011-05-10 | Depuy Products, Inc. | Nail plate |
US20040111090A1 (en) * | 2002-10-03 | 2004-06-10 | The University Of North Carolina At Chapel Hill | Modification of percutaneous intrafocal plate system |
US20050187551A1 (en) * | 2002-12-02 | 2005-08-25 | Orbay Jorge L. | Bone plate system with bone screws fixed by secondary compression |
US7425213B2 (en) * | 2002-12-10 | 2008-09-16 | Depuy Products, Inc. | Method of endosteal nailing |
DE20300987U1 (en) * | 2003-01-23 | 2003-04-10 | Stryker Trauma Gmbh | Implant for osteosynthesis |
JP4579697B2 (en) | 2003-03-07 | 2010-11-10 | ジンテーズ ゲゼルシャフト ミト ベシュレンクテル ハフツング | Set screw for intramedullary nail |
US20040193155A1 (en) * | 2003-03-27 | 2004-09-30 | Hand Innovations, Inc. | Fracture fixation plate with particular plate hole and fastener engagement and methods of using the same |
CA2531541C (en) * | 2003-06-12 | 2011-05-10 | Synthes (U.S.A.) | Surgical nail |
WO2004110290A1 (en) | 2003-06-12 | 2004-12-23 | Synthes Ag Chur | Surgical nail |
DE50311031D1 (en) | 2003-07-30 | 2009-02-12 | Synthes Gmbh | SURGICAL NAIL |
WO2005020830A1 (en) | 2003-08-29 | 2005-03-10 | Synthes Gmbh | Intramedullary nail |
AU2004294998B2 (en) | 2003-12-01 | 2011-03-24 | Smith & Nephew, Inc. | Humeral nail with insert for fixing a screw |
US20060015101A1 (en) * | 2004-07-15 | 2006-01-19 | Wright Medical Technology, Inc. | Intramedullary fixation assembly and devices and methods for installing the same |
US7588577B2 (en) * | 2004-07-15 | 2009-09-15 | Wright Medical Technology, Inc. | Guide assembly for intramedullary fixation and method of using the same |
AU2006207962B2 (en) * | 2005-01-28 | 2012-03-01 | Biomet C.V. | Nail plate system |
US7410488B2 (en) * | 2005-02-18 | 2008-08-12 | Smith & Nephew, Inc. | Hindfoot nail |
DE102005009347B8 (en) | 2005-03-01 | 2008-11-20 | Gradl Medizintechnik Gmbh | Locking device for a broken or broken bone |
US7491202B2 (en) * | 2005-03-31 | 2009-02-17 | Covidien Ag | Electrosurgical forceps with slow closure sealing plates and method of sealing tissue |
US8961516B2 (en) | 2005-05-18 | 2015-02-24 | Sonoma Orthopedic Products, Inc. | Straight intramedullary fracture fixation devices and methods |
US9060820B2 (en) | 2005-05-18 | 2015-06-23 | Sonoma Orthopedic Products, Inc. | Segmented intramedullary fracture fixation devices and methods |
WO2006124764A1 (en) * | 2005-05-18 | 2006-11-23 | Sonoma Orthopedic Products, Inc. | Minimally invasive actuable bone fixation devices, systems and methods of use |
US7905909B2 (en) * | 2005-09-19 | 2011-03-15 | Depuy Products, Inc. | Bone stabilization system including multi-directional threaded fixation element |
KR100851643B1 (en) * | 2005-12-09 | 2008-08-13 | 신세스 게엠바하 | Surgical nail |
GB2442706A (en) * | 2006-10-09 | 2008-04-16 | Mohamed Khalid | An intramedullary rod for the fixation of bone fractures |
US20080149115A1 (en) * | 2006-11-22 | 2008-06-26 | Sonoma Orthopedic Products, Inc. | Surgical station for orthopedic reconstruction surgery |
CA2670263A1 (en) | 2006-11-22 | 2008-05-29 | Sonoma Orthopedic Products, Inc. | Fracture fixation device, tools and methods |
US20080132896A1 (en) * | 2006-11-22 | 2008-06-05 | Sonoma Orthopedic Products, Inc. | Curved orthopedic tool |
US7722611B2 (en) * | 2007-03-05 | 2010-05-25 | Depuy Products, Inc. | Method of treating a clavicle fracture |
JP5499244B2 (en) * | 2007-04-27 | 2014-05-21 | ジンテス ゲゼルシャフト ミット ベシュレンクテル ハフツング | Implant device composed of metal and polymer elements |
US8771283B2 (en) * | 2007-12-17 | 2014-07-08 | Wright Medical Technology, Inc. | Guide assembly for intramedullary fixation and method of using the same |
WO2009152273A1 (en) * | 2008-06-10 | 2009-12-17 | Sonoma Orthopedic Products, Inc. | Fracture fixation device, tools and methods |
CA2738478A1 (en) | 2008-09-26 | 2010-04-01 | Sonoma Orthopedic Products, Inc. | Bone fixation device, tools and methods |
WO2013095756A1 (en) | 2011-12-20 | 2013-06-27 | Synthes Usa, Llc | Self centering feature for an intramedullary nail |
EP2811927B1 (en) | 2012-02-07 | 2017-05-10 | MNR Device Corporation | Apparatus for treating a bone fracture |
DE102013005413A1 (en) * | 2013-03-28 | 2014-10-02 | Dietmar Wolter | Osteosynthesis system for the multidirectional, angularly stable treatment of fractures of long bones including an intramedullary nail and bone screws |
US9770278B2 (en) | 2014-01-17 | 2017-09-26 | Arthrex, Inc. | Dual tip guide wire |
US9814499B2 (en) | 2014-09-30 | 2017-11-14 | Arthrex, Inc. | Intramedullary fracture fixation devices and methods |
US10213250B2 (en) | 2015-11-05 | 2019-02-26 | Covidien Lp | Deployment and safety mechanisms for surgical instruments |
EP3694430A1 (en) | 2017-10-11 | 2020-08-19 | Tornier, Inc. | Humeral fixation plate guides |
EP3740145A1 (en) | 2018-01-15 | 2020-11-25 | GLW, Inc. | Hybrid intramedullary rods |
US11617604B2 (en) | 2020-04-15 | 2023-04-04 | DePuy Synthes Products, Inc. | Intramedullary nail assembly |
Family Cites Families (14)
Publication number | Priority date | Publication date | Assignee | Title |
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US3596656A (en) * | 1969-01-21 | 1971-08-03 | Bernd B Kaute | Fracture fixation device |
US4338926A (en) * | 1980-11-21 | 1982-07-13 | Howmedica, Inc. | Bone fracture prosthesis with controlled stiffness |
DE3200156C2 (en) * | 1982-01-04 | 1984-03-08 | Mecron Medizinische Produkte Gmbh, 1000 Berlin | Screw connection for compressing a repositioned bone fracture |
US4457301A (en) * | 1982-06-18 | 1984-07-03 | Howmedica Inc. | Intramedullary fixation device |
DE8534358U1 (en) * | 1985-12-06 | 1986-01-23 | Howmedica GmbH Werk Schönkirchen, 2314 Schönkirchen | Bone nail for treating upper arm fractures |
CH670381A5 (en) * | 1986-05-05 | 1989-06-15 | Sulzer Ag | |
US4733654A (en) * | 1986-05-29 | 1988-03-29 | Marino James F | Intramedullar nailing assembly |
DE3729840C1 (en) * | 1987-09-05 | 1989-02-02 | Dauerer Hermann Heinrich Micha | Medullary cavity - locking nail |
US4851008A (en) * | 1988-02-01 | 1989-07-25 | Orthomet, Inc. | Bone implant prosthesis with substantially stress-free outer surface |
DE8811634U1 (en) * | 1988-09-14 | 1990-01-11 | Fux, Heinz-Dieter, Dr.Med., 6729 Leimersheim, De | |
CA2014973A1 (en) * | 1989-04-24 | 1990-10-24 | Richard F. Kyle | Intramedullary nail |
SU1692566A1 (en) * | 1989-05-25 | 1991-11-23 | Г.Г. Фишер, В.П. Пишак и В.М. Василов | Intramedullar fixative for treatment of tubular bone fractures |
DE3921972C2 (en) * | 1989-07-04 | 1994-06-09 | Rainer Dr Med Baumgart | Intramedullary nail |
US5127913A (en) * | 1991-04-22 | 1992-07-07 | Thomas Jr Charles B | Apparatus and method for implanting an intramedullary rod |
-
1992
- 1992-02-20 DE DE4205118A patent/DE4205118C1/de not_active Expired - Fee Related
-
1993
- 1993-02-11 AT AT93903175T patent/ATE143787T1/en active
- 1993-02-11 EP EP93903175A patent/EP0583442B1/en not_active Expired - Lifetime
- 1993-02-11 WO PCT/DE1993/000135 patent/WO1993015679A1/en active IP Right Grant
- 1993-02-11 CA CA002108249A patent/CA2108249A1/en not_active Abandoned
- 1993-02-11 DE DE59304096T patent/DE59304096D1/en not_active Expired - Fee Related
- 1993-02-11 JP JP5513582A patent/JPH06507104A/en active Pending
- 1993-02-11 ES ES93903175T patent/ES2093405T3/en not_active Expired - Lifetime
-
1994
- 1994-11-23 US US08/344,223 patent/US5484438A/en not_active Expired - Fee Related
Also Published As
Publication number | Publication date |
---|---|
WO1993015679A1 (en) | 1993-08-19 |
US5484438A (en) | 1996-01-16 |
EP0583442B1 (en) | 1996-10-09 |
EP0583442A1 (en) | 1994-02-23 |
DE4205118C1 (en) | 1993-07-29 |
JPH06507104A (en) | 1994-08-11 |
ES2093405T3 (en) | 1996-12-16 |
ATE143787T1 (en) | 1996-10-15 |
DE59304096D1 (en) | 1996-11-14 |
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