CA2116441A1 - Extendable guidewire assembly - Google Patents
Extendable guidewire assemblyInfo
- Publication number
- CA2116441A1 CA2116441A1 CA002116441A CA2116441A CA2116441A1 CA 2116441 A1 CA2116441 A1 CA 2116441A1 CA 002116441 A CA002116441 A CA 002116441A CA 2116441 A CA2116441 A CA 2116441A CA 2116441 A1 CA2116441 A1 CA 2116441A1
- Authority
- CA
- Canada
- Prior art keywords
- sleeve
- guidewire
- lumen
- extension wire
- extendable
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Abandoned
Links
- 230000006835 compression Effects 0.000 claims abstract description 3
- 238000007906 compression Methods 0.000 claims abstract description 3
- 239000004642 Polyimide Substances 0.000 claims description 5
- 229920001721 polyimide Polymers 0.000 claims description 5
- 210000005166 vasculature Anatomy 0.000 claims description 3
- 238000000034 method Methods 0.000 description 4
- 229920000642 polymer Polymers 0.000 description 3
- 239000004593 Epoxy Substances 0.000 description 2
- 230000002844 continuous effect Effects 0.000 description 2
- 238000004519 manufacturing process Methods 0.000 description 2
- 239000010959 steel Substances 0.000 description 2
- 229910000851 Alloy steel Inorganic materials 0.000 description 1
- 229910000831 Steel Inorganic materials 0.000 description 1
- 239000000853 adhesive Substances 0.000 description 1
- 230000001070 adhesive effect Effects 0.000 description 1
- 230000002526 effect on cardiovascular system Effects 0.000 description 1
- 229920006332 epoxy adhesive Polymers 0.000 description 1
- 238000010438 heat treatment Methods 0.000 description 1
- 239000000463 material Substances 0.000 description 1
- 229910001000 nickel titanium Inorganic materials 0.000 description 1
- 239000010409 thin film Substances 0.000 description 1
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
- A61M25/00—Catheters; Hollow probes
- A61M25/01—Introducing, guiding, advancing, emplacing or holding catheters
- A61M25/09—Guide wires
- A61M25/0905—Guide wires extendable, e.g. mechanisms for extension
Abstract
An extendable guidewire assembly comprising: a guidewire (11) having a tapered proximal end; an extension wire (12) having a tapered distal end; and a polymeric tubular sleeve (13) that is fixedly attached about the tapered distal end of the extension wire such that the tapered distal end of the extension wire extends partly through the sleeve lumen, said lumen having a diameter that is smaller than the untapered diameter of the guidewire and wherein said lumen expands radially when the sleeve is under axial compression and contracts radially when the sleeve is under axial tension.
Description
Description Technical Field This invention i9 in the general field o~
~urgical in truments and relate~ 3pecifically to an extendable ~uidewire assembly that in used in cardiovascular and endovascular procedures to facilitate the placement of catheters within the ~a~culature of patients.
Backqro~nd The general procedure for placing catheters within ve3sels i8 to track a yuidewire through the vessel to the desired position and ad~ance the ca~heter over the guidewire. Guidewires are required becau~e the catheters them~elves do not have sufficient column strength or torqueability to be able to be tracked or steered through the vessel. See; for in~tance, U.S. Pat. No. 4,884,~79.
-In some pr4cedures 4uch as angioplas~y u~ing dilatation balloon catheter~ i8 ~eces~ary to excha~ge catheters to increase balloon size. It may al80 be nece~ary i~ ~ome insta~ces to replace catheters due to material fatigue. Two guidewire techniques have been employed in such in~tance~. In one, the initial guidewire i8 removed and replaced with an exchange-wire that i~ omewhat greater than double the length of the catheter. In order to a~oid the need for a separate W093/~3786 PCT/US92/07035 ~ 2 exchange wire a second technique that involve~ attaching an extension wire to the initial guidewire was developed.
U.S. Pats. Nos. 4,917,103 and 4,922,923 , describe an extendable guidewire assembly that employs a sleeve that is connected to the proximal end of the --guidewire and into which the di~tal end of the extension wire is inserted. The sleeve and extension are then crimped to fonm a permanent joint or union between the two wires.
U.S. 4,875,4~9 describes another type of extendable guidewire assembly in which one of the wires has a tapered tip and the other has an expandable sleeve into which the tip is received. A second concentric sleeve enclose~ the expandable sleeve to en~ure a friction fit between the tapered tip and expandable sleeve.
U.S. 4,966,163 describes yet another ~ind of extendable guidewire as~embly. In this assembly one of the wires carries an internally threaded sleeve and the -~
other wire carries a threaded head. m e two wires are coupled together by threading the head into the sleeve.
Commonly-owned copending U.S. application ' Serial No.-688,915, filed 19 April 1991, describes an '' extendable,guidewire,assembly in which the ends of the guidewire and extension wire carry axial interlocking members and-the extension wire carries a retractable -~
sleeve~which encloses the interlocked members.
~ ,,Applicant is also aware of an extendable, guidewire assembly design in which one of the wires carries an open-ended sleeve and the,other wire has a tapered,,tip encircled by a helical coil. The wires are coupled by inserting the tip into the sleeve and twisting it. The twisting causes the coil to expand and fonm a ' - friction fit with the interior of the slee~e. The wires W093/03786 l;~ PCT/US92/07035 3 ~ ~ ~ iil are uncoupled by twisting the tapered tip wire in the reverse direction.
A primary object of the pre~ent invention is to provide an extendable guidewire as~embly that may be connected and disconnected and is relatively simple-to manufacture.
Disclosure of ~he Invçntion The invention is an extendable guidewire a~sembly for use within a patient's va~culature comprising in combination:
(a) a guidewire having a distal end that is adapted to be fed into said vasculature and a tapered proximal end;
(b) an exten~ion wire having a proximal end and a tapered distal end; and (c) a polymeric sleeve ha~ing first and second ends and a lumen extending therebetween, said fir~t end being fixedly attached concentrically about one of either the proximal end of-the auidewire or the distal end of the extension wire such that said one end extend~ partly through the lumen of the slee~e, said second end being adapted to recei~e the other of the proximal end of the auidewire or the distal end of the extension wire, said lumen ha~ing a diameter tha~ is smaller than the untapered-diameter of the wire to which the sleeve i8 not fixedly attachéd and wherein the lumen expands radially when the sleeve is under axial ~ompression and contracts radially when the ~lee~e is under axial tension.
9rief Descri~tion of the Drawinas Figure 1 is a fragmentary ele~ational ~iew of a preferred embodiment of the extendable guidewire with the guidewire and extension wire in a disconnected configuration.
WOg3/037~ PCT/US92/07035 ~ 4 Figure 2 i9 a fraamentary ele~ational view of the embodiment of Figure 1 with the guidewire and extension wires on their connected configurations.
Modes for Carryina Out the Invention --The drawings illustrate the preferred embodiment of the extendable guidewire assembly of the invention. The three principal components of the a~sembly are: a guidewire 11, an extension wire 12, and a sleeve 13. In these figures only the proximal end 14 of the guidewire and the di~tal end 15 of the extension wire are shown. The remainder~ of the two wires are not shown and are of conventional structure.
While this invention may be practiced with guidewires of any length and diameter, it will typically be employed with stainle~s steel or nickel-titanium alloy guidewires and extensions that are c 0.46 mm in diameter (untapered), more normally 0.25 to 0.40 mm in diameter (untapered). Preferably, the diameters of the guidewire and exten~ion wise are the same. In most instances the length of the guidewire will be in the range of 100-200 cm and the extension will be on the order of 125 to 225 cm in length.
The proximal end 14 of guidewire 11 has a tapered ~ection i6.~ For manufacturing convenience the taper will noDmally be conical, although other taper-cGnfigurations may be used. The taper i8 continuou~ and the length of ~ection 16 will normally be 3 to 7 cm, more u~ually 5 to 6 cm.
m e distal end 15~ of the extension wire 12 has a ~imilarly tapered section 17. It, too, is preferably conical, continuou~ and extends over a length of 3 to 7 cm, usually 5 to 6 cm.
Sleeve 13 preferably ha~ an outer diameter that is equal to or less than the outer diameter~ of the W093/037~ L PCT/US92/07035 untapered portion~ of the guidewire and extension wire.
Correspondingly, the diameter of its lumen ~8 will be less than the individual diameters (untapered) of the two wires. The lumen diameter will typically be 0.2 to 0.36 mm, more usually 0.25 to 0.30 mm. In the embodiment ;~
shown in the drawing the sleeve is attached to the tapered end of the extension wire by mean~ of an adhesive 19. ~ecause the diameter of the lumen 18 is smaller than the untapered diameter of the extension wire, the site of affixation i~ on the tapered portion.
The length of tubular sleeve 13 is such that the tapered portion 17 of the extension wire extends within the lumen over half the length of the sleeve. As shown in the drawing, when the wires are connected the tapered end of the guidewire also extends into the lumen over half the length of the sleeve. Thus, the tapered tips of the wires axially overlap within the lumen. With wires of the dimensions given above, the length of the sleeve will usually be 5 to 8 cm, more usually 6 to 7.5 cm.
- The tube is made of a polymer that will provide a friction fit between the contact surface between it~
inner wall and the tapered section 16 of the guidewire.
Further, the nature of the mechanical properties of the polymer and the wall thickness of the ~leeve are such that the ~leeve will act as a ~Chinese finger tube" and -it~ lumen will expand when the ~leeve i9 under axial compression and contract when the sleeve is under axial ten~on. In this regard the wall thickness of the sleeve will usually be 0.025 to 0.05 mm and~the sleeve will be made-of polyimide or other polymer of like mechanical properties.
- - The guidewire and extension wire are connected - by ~imply in~erting the tapered end of the guidewire into the sleeve until a tight friction fit between the sleeve ~ 6-and the tapered end of the guidewire i5 achieved. ~See Fig. 2.) Locking of the connection between the wires may be verified by applying axial tension to both wires close to the sleeve junction. Because of the "Chinese finger tube" fit, the wires can be disconnected only by placing force on (gripping) the distal end face 20 of the sleeve, and pulling the tapered end of the guidewire from the lumen. Any manipulation that places the sleeve under axial tension contracts the lumen and exerts radial force at the contact ~urfaces of the sleeve and the tapered portion of the guidewire.
An extendable guidewire assembly according to the invention was made as follows. Using a centerless grinder, the proximal end a 195 cm long stainles~ steel - 15 catheter guidewire having a 0.014 n OD was ground to 0.002~ tip OD with a 6.0 cm taper length. The end of a different wire of the same diameter, about 160 cm long, was ground similarly as the guidewire. This wire served as the extension wire. Polyimide tubing (purchased from H.V. Technology) with a 0.013~ OD and a O.001 n wall thickness was cut squarely to about 7.5 cm long. A thin film of epoxy adhesive was applied on the ground segment of the extension wire. The tip of the extension wire was inserted into the polyimide tubing and pressed until the wire locked. The epoxy wa~ allowed to cure overnight.
Alternatively the epoxy may be cured by heating for 3 min at - 135C. Exten~ion of the guidewire was accomplished by inserting the ground proximal end of the ~uidewire into the polyimide tube of the exten~ion wire. The catheter wire was pres~ed firmly into the tubing.
While the above-described embodiment ~hows the sleeve affixed to the extension wire, it will be appreciated that the respective wire structures may be - reversed (i.e., the sleeve is affixed to the proximal end of the guidewire). Similarly, other modificationq of the W093/03786 , PCT/US92/07035 7 ~ ~
above-described embodiment of the in~ention that are obvious to those of ~kill in the mechanical and guidewire/catheter arts are intended to be within the scope of the following ciaims.
.,
~urgical in truments and relate~ 3pecifically to an extendable ~uidewire assembly that in used in cardiovascular and endovascular procedures to facilitate the placement of catheters within the ~a~culature of patients.
Backqro~nd The general procedure for placing catheters within ve3sels i8 to track a yuidewire through the vessel to the desired position and ad~ance the ca~heter over the guidewire. Guidewires are required becau~e the catheters them~elves do not have sufficient column strength or torqueability to be able to be tracked or steered through the vessel. See; for in~tance, U.S. Pat. No. 4,884,~79.
-In some pr4cedures 4uch as angioplas~y u~ing dilatation balloon catheter~ i8 ~eces~ary to excha~ge catheters to increase balloon size. It may al80 be nece~ary i~ ~ome insta~ces to replace catheters due to material fatigue. Two guidewire techniques have been employed in such in~tance~. In one, the initial guidewire i8 removed and replaced with an exchange-wire that i~ omewhat greater than double the length of the catheter. In order to a~oid the need for a separate W093/~3786 PCT/US92/07035 ~ 2 exchange wire a second technique that involve~ attaching an extension wire to the initial guidewire was developed.
U.S. Pats. Nos. 4,917,103 and 4,922,923 , describe an extendable guidewire assembly that employs a sleeve that is connected to the proximal end of the --guidewire and into which the di~tal end of the extension wire is inserted. The sleeve and extension are then crimped to fonm a permanent joint or union between the two wires.
U.S. 4,875,4~9 describes another type of extendable guidewire assembly in which one of the wires has a tapered tip and the other has an expandable sleeve into which the tip is received. A second concentric sleeve enclose~ the expandable sleeve to en~ure a friction fit between the tapered tip and expandable sleeve.
U.S. 4,966,163 describes yet another ~ind of extendable guidewire as~embly. In this assembly one of the wires carries an internally threaded sleeve and the -~
other wire carries a threaded head. m e two wires are coupled together by threading the head into the sleeve.
Commonly-owned copending U.S. application ' Serial No.-688,915, filed 19 April 1991, describes an '' extendable,guidewire,assembly in which the ends of the guidewire and extension wire carry axial interlocking members and-the extension wire carries a retractable -~
sleeve~which encloses the interlocked members.
~ ,,Applicant is also aware of an extendable, guidewire assembly design in which one of the wires carries an open-ended sleeve and the,other wire has a tapered,,tip encircled by a helical coil. The wires are coupled by inserting the tip into the sleeve and twisting it. The twisting causes the coil to expand and fonm a ' - friction fit with the interior of the slee~e. The wires W093/03786 l;~ PCT/US92/07035 3 ~ ~ ~ iil are uncoupled by twisting the tapered tip wire in the reverse direction.
A primary object of the pre~ent invention is to provide an extendable guidewire as~embly that may be connected and disconnected and is relatively simple-to manufacture.
Disclosure of ~he Invçntion The invention is an extendable guidewire a~sembly for use within a patient's va~culature comprising in combination:
(a) a guidewire having a distal end that is adapted to be fed into said vasculature and a tapered proximal end;
(b) an exten~ion wire having a proximal end and a tapered distal end; and (c) a polymeric sleeve ha~ing first and second ends and a lumen extending therebetween, said fir~t end being fixedly attached concentrically about one of either the proximal end of-the auidewire or the distal end of the extension wire such that said one end extend~ partly through the lumen of the slee~e, said second end being adapted to recei~e the other of the proximal end of the auidewire or the distal end of the extension wire, said lumen ha~ing a diameter tha~ is smaller than the untapered-diameter of the wire to which the sleeve i8 not fixedly attachéd and wherein the lumen expands radially when the sleeve is under axial ~ompression and contracts radially when the ~lee~e is under axial tension.
9rief Descri~tion of the Drawinas Figure 1 is a fragmentary ele~ational ~iew of a preferred embodiment of the extendable guidewire with the guidewire and extension wire in a disconnected configuration.
WOg3/037~ PCT/US92/07035 ~ 4 Figure 2 i9 a fraamentary ele~ational view of the embodiment of Figure 1 with the guidewire and extension wires on their connected configurations.
Modes for Carryina Out the Invention --The drawings illustrate the preferred embodiment of the extendable guidewire assembly of the invention. The three principal components of the a~sembly are: a guidewire 11, an extension wire 12, and a sleeve 13. In these figures only the proximal end 14 of the guidewire and the di~tal end 15 of the extension wire are shown. The remainder~ of the two wires are not shown and are of conventional structure.
While this invention may be practiced with guidewires of any length and diameter, it will typically be employed with stainle~s steel or nickel-titanium alloy guidewires and extensions that are c 0.46 mm in diameter (untapered), more normally 0.25 to 0.40 mm in diameter (untapered). Preferably, the diameters of the guidewire and exten~ion wise are the same. In most instances the length of the guidewire will be in the range of 100-200 cm and the extension will be on the order of 125 to 225 cm in length.
The proximal end 14 of guidewire 11 has a tapered ~ection i6.~ For manufacturing convenience the taper will noDmally be conical, although other taper-cGnfigurations may be used. The taper i8 continuou~ and the length of ~ection 16 will normally be 3 to 7 cm, more u~ually 5 to 6 cm.
m e distal end 15~ of the extension wire 12 has a ~imilarly tapered section 17. It, too, is preferably conical, continuou~ and extends over a length of 3 to 7 cm, usually 5 to 6 cm.
Sleeve 13 preferably ha~ an outer diameter that is equal to or less than the outer diameter~ of the W093/037~ L PCT/US92/07035 untapered portion~ of the guidewire and extension wire.
Correspondingly, the diameter of its lumen ~8 will be less than the individual diameters (untapered) of the two wires. The lumen diameter will typically be 0.2 to 0.36 mm, more usually 0.25 to 0.30 mm. In the embodiment ;~
shown in the drawing the sleeve is attached to the tapered end of the extension wire by mean~ of an adhesive 19. ~ecause the diameter of the lumen 18 is smaller than the untapered diameter of the extension wire, the site of affixation i~ on the tapered portion.
The length of tubular sleeve 13 is such that the tapered portion 17 of the extension wire extends within the lumen over half the length of the sleeve. As shown in the drawing, when the wires are connected the tapered end of the guidewire also extends into the lumen over half the length of the sleeve. Thus, the tapered tips of the wires axially overlap within the lumen. With wires of the dimensions given above, the length of the sleeve will usually be 5 to 8 cm, more usually 6 to 7.5 cm.
- The tube is made of a polymer that will provide a friction fit between the contact surface between it~
inner wall and the tapered section 16 of the guidewire.
Further, the nature of the mechanical properties of the polymer and the wall thickness of the ~leeve are such that the ~leeve will act as a ~Chinese finger tube" and -it~ lumen will expand when the ~leeve i9 under axial compression and contract when the sleeve is under axial ten~on. In this regard the wall thickness of the sleeve will usually be 0.025 to 0.05 mm and~the sleeve will be made-of polyimide or other polymer of like mechanical properties.
- - The guidewire and extension wire are connected - by ~imply in~erting the tapered end of the guidewire into the sleeve until a tight friction fit between the sleeve ~ 6-and the tapered end of the guidewire i5 achieved. ~See Fig. 2.) Locking of the connection between the wires may be verified by applying axial tension to both wires close to the sleeve junction. Because of the "Chinese finger tube" fit, the wires can be disconnected only by placing force on (gripping) the distal end face 20 of the sleeve, and pulling the tapered end of the guidewire from the lumen. Any manipulation that places the sleeve under axial tension contracts the lumen and exerts radial force at the contact ~urfaces of the sleeve and the tapered portion of the guidewire.
An extendable guidewire assembly according to the invention was made as follows. Using a centerless grinder, the proximal end a 195 cm long stainles~ steel - 15 catheter guidewire having a 0.014 n OD was ground to 0.002~ tip OD with a 6.0 cm taper length. The end of a different wire of the same diameter, about 160 cm long, was ground similarly as the guidewire. This wire served as the extension wire. Polyimide tubing (purchased from H.V. Technology) with a 0.013~ OD and a O.001 n wall thickness was cut squarely to about 7.5 cm long. A thin film of epoxy adhesive was applied on the ground segment of the extension wire. The tip of the extension wire was inserted into the polyimide tubing and pressed until the wire locked. The epoxy wa~ allowed to cure overnight.
Alternatively the epoxy may be cured by heating for 3 min at - 135C. Exten~ion of the guidewire was accomplished by inserting the ground proximal end of the ~uidewire into the polyimide tube of the exten~ion wire. The catheter wire was pres~ed firmly into the tubing.
While the above-described embodiment ~hows the sleeve affixed to the extension wire, it will be appreciated that the respective wire structures may be - reversed (i.e., the sleeve is affixed to the proximal end of the guidewire). Similarly, other modificationq of the W093/03786 , PCT/US92/07035 7 ~ ~
above-described embodiment of the in~ention that are obvious to those of ~kill in the mechanical and guidewire/catheter arts are intended to be within the scope of the following ciaims.
.,
Claims (7)
1. An extendable guidewire assembly for use within a patient's vasculature comprising in combination:
(a) a guidewire having a distal end that-is adapted to be fed into said vasculature and a tapered proximal end;
(b) an extension wire having a proximal end and a tapered distal end; and (c) a polymeric sleeve having first and second ends and a lumen extending therebetween, said first end being fixedly attached concentrically about one of either the proximal end of the guidewire or the distal end of the extension wire, such that said one end extends partly through the lumen of the sleeve, said second end being adapted to receive the other of the proximal end of the guidewire or the distal end of the extension wire, said lumen having a diameter that is smaller than the diameter of the wire to which the sleeve is not fixedly attached and wherein said lumen expands radially when the sleeve is under axial compression and contracts radially when the sleeve is under axial tension.
(a) a guidewire having a distal end that-is adapted to be fed into said vasculature and a tapered proximal end;
(b) an extension wire having a proximal end and a tapered distal end; and (c) a polymeric sleeve having first and second ends and a lumen extending therebetween, said first end being fixedly attached concentrically about one of either the proximal end of the guidewire or the distal end of the extension wire, such that said one end extends partly through the lumen of the sleeve, said second end being adapted to receive the other of the proximal end of the guidewire or the distal end of the extension wire, said lumen having a diameter that is smaller than the diameter of the wire to which the sleeve is not fixedly attached and wherein said lumen expands radially when the sleeve is under axial compression and contracts radially when the sleeve is under axial tension.
2. The extendable guidewire assembly of claim 1 wherein the sleeve is fixedly attached about the distal end of the extension wire.
3. The extendable guidewire assembly of claim 1 wherein the taper of the proximal end of the guidewire is a conical taper and the taper of the distal end of the extension wire is a conical taper.
4. The extendable guidewire assembly of claim 1 wherein said one end to which the sleeve is fixedly attached extends through greater than half the length of the sleeve lumen.
5. The extendable guidewire assembly of claim 2 wherein the untapered diameter of the guidewire is about 0.3 to 0.4 mm, the untapered diameter of the extension wire is about 0.3 to 0.4 mm, and the diameter of the sleeve lumen is less than said untapered diameter of the guidewire.
6. The extendable guidewire assembly of claim 5 wherein the length of the tapered end of the guidewire is 3 to 7 cm, the length of the tapered end of the extension wire is 3 to 7 cm and the length of the sleeve is 5 to 8 cm.
7. The extendable guidewire assembly of claim 1 wherein the sleeve is made of polyimide and the wall thickness of the sleeve is 0.025 to 0.05 mm.
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US750,558 | 1991-08-26 | ||
| US07/750,558 US5188621A (en) | 1991-08-26 | 1991-08-26 | Extendable guidewire assembly |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| CA2116441A1 true CA2116441A1 (en) | 1993-03-04 |
Family
ID=25018330
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| CA002116441A Abandoned CA2116441A1 (en) | 1991-08-26 | 1992-08-19 | Extendable guidewire assembly |
Country Status (10)
| Country | Link |
|---|---|
| US (2) | US5188621A (en) |
| EP (1) | EP0601044A4 (en) |
| JP (1) | JPH07500738A (en) |
| AU (1) | AU662166B2 (en) |
| CA (1) | CA2116441A1 (en) |
| IL (1) | IL102850A (en) |
| NZ (1) | NZ244033A (en) |
| PT (1) | PT100813A (en) |
| TW (1) | TW216401B (en) |
| WO (1) | WO1993003786A1 (en) |
Families Citing this family (128)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| USRE42756E1 (en) | 1990-03-13 | 2011-09-27 | The Regents Of The University Of California | Endovascular electrolytically detachable wire and tip for the formation of thrombus in arteries, veins, aneurysms, vascular malformations and arteriovenous fistulas |
| US6083220A (en) | 1990-03-13 | 2000-07-04 | The Regents Of The University Of California | Endovascular electrolytically detachable wire and tip for the formation of thrombus in arteries, veins, aneurysms, vascular malformations and arteriovenous fistulas |
| USRE42625E1 (en) | 1990-03-13 | 2011-08-16 | The Regents Of The University Of California | Endovascular electrolytically detachable wire and tip for the formation of thrombus in arteries, veins, aneurysms, vascular malformations and arteriovenous fistulas |
| US6682608B2 (en) | 1990-12-18 | 2004-01-27 | Advanced Cardiovascular Systems, Inc. | Superelastic guiding member |
| US5341818A (en) | 1992-12-22 | 1994-08-30 | Advanced Cardiovascular Systems, Inc. | Guidewire with superelastic distal portion |
| US6165292A (en) * | 1990-12-18 | 2000-12-26 | Advanced Cardiovascular Systems, Inc. | Superelastic guiding member |
| US5415178A (en) * | 1991-08-26 | 1995-05-16 | Target Therapeutics | Extendable guidewire assembly |
| US5404888A (en) * | 1992-02-10 | 1995-04-11 | Datascope Investment Corp. | Guide wire extension |
| US5341817A (en) * | 1992-12-14 | 1994-08-30 | Cordis Corporation | Elongated guidewire for use in dilation procedures |
| US5404886A (en) * | 1993-05-14 | 1995-04-11 | Schneider (Usa) Inc. | Exchangeable guidewire |
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| ES2094010T3 (en) * | 1994-05-11 | 1997-01-01 | Schneider Europ Ag | ASSEMBLY FOR THE EXTENSION OF A GUIDE WIRE. |
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| US5513650A (en) * | 1995-02-28 | 1996-05-07 | Medtronic, Inc. | Guidewire extension connector - keyed joint |
| EP0827383B1 (en) * | 1995-02-28 | 2007-05-30 | Boston Scientific Corporation | Polymer implements for torque transmission |
| US5792075A (en) * | 1995-04-11 | 1998-08-11 | Schneider (Europe) A.G. | Method and apparatus for extending the length of a guide wire |
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| US5109867A (en) * | 1991-04-19 | 1992-05-05 | Target Therapeutics | Extendable guidewire assembly |
-
1991
- 1991-08-26 US US07/750,558 patent/US5188621A/en not_active Expired - Fee Related
-
1992
- 1992-08-18 IL IL10285092A patent/IL102850A/en not_active IP Right Cessation
- 1992-08-19 EP EP19920918716 patent/EP0601044A4/en not_active Ceased
- 1992-08-19 AU AU25000/92A patent/AU662166B2/en not_active Ceased
- 1992-08-19 WO PCT/US1992/007035 patent/WO1993003786A1/en not_active Application Discontinuation
- 1992-08-19 JP JP5504591A patent/JPH07500738A/en active Pending
- 1992-08-19 CA CA002116441A patent/CA2116441A1/en not_active Abandoned
- 1992-08-20 NZ NZ24403392A patent/NZ244033A/en unknown
- 1992-08-26 PT PT100813A patent/PT100813A/en not_active Application Discontinuation
- 1992-12-01 US US07/983,478 patent/US5275173A/en not_active Expired - Lifetime
-
1993
- 1993-01-15 TW TW082100236A patent/TW216401B/zh active
Also Published As
| Publication number | Publication date |
|---|---|
| EP0601044A4 (en) | 1994-07-20 |
| EP0601044A1 (en) | 1994-06-15 |
| AU2500092A (en) | 1993-03-16 |
| AU662166B2 (en) | 1995-08-24 |
| US5275173A (en) | 1994-01-04 |
| US5188621A (en) | 1993-02-23 |
| NZ244033A (en) | 1994-07-26 |
| IL102850A0 (en) | 1993-01-31 |
| JPH07500738A (en) | 1995-01-26 |
| WO1993003786A1 (en) | 1993-03-04 |
| IL102850A (en) | 1995-08-31 |
| PT100813A (en) | 1994-05-31 |
| TW216401B (en) | 1993-11-21 |
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Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| EEER | Examination request | ||
| FZDE | Discontinued |