CA2135170A1 - Luminometer with Reduced Sample Crosstalk - Google Patents

Luminometer with Reduced Sample Crosstalk

Info

Publication number
CA2135170A1
CA2135170A1 CA 2135170 CA2135170A CA2135170A1 CA 2135170 A1 CA2135170 A1 CA 2135170A1 CA 2135170 CA2135170 CA 2135170 CA 2135170 A CA2135170 A CA 2135170A CA 2135170 A1 CA2135170 A1 CA 2135170A1
Authority
CA
Canada
Prior art keywords
tray
photodetector assembly
luminometer
photodetector
head
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Granted
Application number
CA 2135170
Other languages
French (fr)
Other versions
CA2135170C (en
Inventor
Rick T. Smethers
Brian D. Warner
Victor P. Burolla
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Bayer Corp
Original Assignee
Rick T. Smethers
Brian D. Warner
Victor P. Burolla
Chiron Corporation
Chiron Diagnostics Corporation
Bayer Corporation
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Rick T. Smethers, Brian D. Warner, Victor P. Burolla, Chiron Corporation, Chiron Diagnostics Corporation, Bayer Corporation filed Critical Rick T. Smethers
Publication of CA2135170A1 publication Critical patent/CA2135170A1/en
Application granted granted Critical
Publication of CA2135170C publication Critical patent/CA2135170C/en
Anticipated expiration legal-status Critical
Expired - Fee Related legal-status Critical Current

Links

Classifications

    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N21/00—Investigating or analysing materials by the use of optical means, i.e. using sub-millimetre waves, infrared, visible or ultraviolet light
    • G01N21/75—Systems in which material is subjected to a chemical reaction, the progress or the result of the reaction being investigated
    • G01N21/76—Chemiluminescence; Bioluminescence
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N35/00—Automatic analysis not limited to methods or materials provided for in any single one of groups G01N1/00 - G01N33/00; Handling materials therefor
    • G01N35/02—Automatic analysis not limited to methods or materials provided for in any single one of groups G01N1/00 - G01N33/00; Handling materials therefor using a plurality of sample containers moved by a conveyor system past one or more treatment or analysis stations
    • G01N35/028—Automatic analysis not limited to methods or materials provided for in any single one of groups G01N1/00 - G01N33/00; Handling materials therefor using a plurality of sample containers moved by a conveyor system past one or more treatment or analysis stations having reaction cells in the form of microtitration plates
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N35/00—Automatic analysis not limited to methods or materials provided for in any single one of groups G01N1/00 - G01N33/00; Handling materials therefor
    • G01N2035/00346—Heating or cooling arrangements
    • G01N2035/00356—Holding samples at elevated temperature (incubation)
    • G01N2035/00376—Conductive heating, e.g. heated plates
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N35/00—Automatic analysis not limited to methods or materials provided for in any single one of groups G01N1/00 - G01N33/00; Handling materials therefor
    • G01N35/02—Automatic analysis not limited to methods or materials provided for in any single one of groups G01N1/00 - G01N33/00; Handling materials therefor using a plurality of sample containers moved by a conveyor system past one or more treatment or analysis stations
    • G01N35/04—Details of the conveyor system
    • G01N2035/0474—Details of actuating means for conveyors or pipettes
    • G01N2035/0482—Transmission
    • G01N2035/0487—Helix or lead screw
    • Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10—TECHNICAL SUBJECTS COVERED BY FORMER USPC
    • Y10S—TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10S435/00—Chemistry: molecular biology and microbiology
    • Y10S435/808—Optical sensing apparatus

Abstract

A luminometer is described comprising a tray for receiving an array of sample wells, a photodetector assembly, and means for relatively moving the tray and photodetector assembly in one direction to align the sample wells received by the tray in a predetermined sequence with the photodetector assembly. The photodetector assembly of the luminometer includes a stage, a photodetection head (73) having a detection aperture permitting passage of light therethrough, a means for mounting the photodetection head to the stage that permits movement of the head in a direction substantially normal to the direction of relative tray and photodetector assembly movement, and a means for biasing the photodetection head toward a selected sample well (72) so that the detection aperture is substantially isolated from light emitted from adjacent wells. Internal and external photodetector calibration systems and a sample heater are also contemplated.
CA002135170A 1992-05-05 1993-05-03 Luminometer with reduced sample crosstalk Expired - Fee Related CA2135170C (en)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US07/878,829 US5401465A (en) 1992-05-05 1992-05-05 Luminometer with reduced sample crosstalk
US07/878,829 1992-05-05
PCT/US1993/004115 WO1993022657A2 (en) 1992-05-05 1993-05-03 Luminometer with reduced sample crosstalk

Publications (2)

Publication Number Publication Date
CA2135170A1 true CA2135170A1 (en) 1993-11-11
CA2135170C CA2135170C (en) 2000-01-25

Family

ID=25372935

Family Applications (1)

Application Number Title Priority Date Filing Date
CA002135170A Expired - Fee Related CA2135170C (en) 1992-05-05 1993-05-03 Luminometer with reduced sample crosstalk

Country Status (8)

Country Link
US (3) US5401465A (en)
EP (1) EP0725929B1 (en)
JP (3) JP2802835B2 (en)
AT (1) ATE210288T1 (en)
CA (1) CA2135170C (en)
DE (1) DE69331281T2 (en)
ES (1) ES2166762T3 (en)
WO (1) WO1993022657A2 (en)

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Also Published As

Publication number Publication date
US5643535A (en) 1997-07-01
EP0725929B1 (en) 2001-12-05
JP2001194293A (en) 2001-07-19
CA2135170C (en) 2000-01-25
US5401465A (en) 1995-03-28
ES2166762T3 (en) 2002-05-01
US5716583A (en) 1998-02-10
JP2802835B2 (en) 1998-09-24
JP3181257B2 (en) 2001-07-03
DE69331281T2 (en) 2002-05-23
WO1993022657A2 (en) 1993-11-11
EP0725929A1 (en) 1996-08-14
JPH10293098A (en) 1998-11-04
JP3513485B2 (en) 2004-03-31
JPH07506433A (en) 1995-07-13
ATE210288T1 (en) 2001-12-15
DE69331281D1 (en) 2002-01-17
WO1993022657A3 (en) 1994-01-20

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