CA2141866A1 - Encapsulating equipment and method - Google Patents

Encapsulating equipment and method

Info

Publication number
CA2141866A1
CA2141866A1 CA002141866A CA2141866A CA2141866A1 CA 2141866 A1 CA2141866 A1 CA 2141866A1 CA 002141866 A CA002141866 A CA 002141866A CA 2141866 A CA2141866 A CA 2141866A CA 2141866 A1 CA2141866 A1 CA 2141866A1
Authority
CA
Canada
Prior art keywords
caplets
gelatin
fitted over
product
overprinting
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Granted
Application number
CA002141866A
Other languages
French (fr)
Other versions
CA2141866C (en
Inventor
Erich W. Sauter
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Capsugel Belgium NV
Original Assignee
Erich W. Sauter
Sauter Manufacturing Corporation
Warner-Lambert Company
Warner-Lambert Company Llc
Capsugel Belgium Bvba
Capsugel Belgium Nv
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Family has litigation
First worldwide family litigation filed litigation Critical https://patents.darts-ip.com/?family=25454115&utm_source=google_patent&utm_medium=platform_link&utm_campaign=public_patent_search&patent=CA2141866(A1) "Global patent litigation dataset” by Darts-ip is licensed under a Creative Commons Attribution 4.0 International License.
Application filed by Erich W. Sauter, Sauter Manufacturing Corporation, Warner-Lambert Company, Warner-Lambert Company Llc, Capsugel Belgium Bvba, Capsugel Belgium Nv filed Critical Erich W. Sauter
Publication of CA2141866A1 publication Critical patent/CA2141866A1/en
Application granted granted Critical
Publication of CA2141866C publication Critical patent/CA2141866C/en
Anticipated expiration legal-status Critical
Expired - Lifetime legal-status Critical Current

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61J—CONTAINERS SPECIALLY ADAPTED FOR MEDICAL OR PHARMACEUTICAL PURPOSES; DEVICES OR METHODS SPECIALLY ADAPTED FOR BRINGING PHARMACEUTICAL PRODUCTS INTO PARTICULAR PHYSICAL OR ADMINISTERING FORMS; DEVICES FOR ADMINISTERING FOOD OR MEDICINES ORALLY; BABY COMFORTERS; DEVICES FOR RECEIVING SPITTLE
    • A61J3/00—Devices or methods specially adapted for bringing pharmaceutical products into particular physical or administering forms
    • A61J3/07—Devices or methods specially adapted for bringing pharmaceutical products into particular physical or administering forms into the form of capsules or similar small containers for oral use
    • A61J3/071—Devices or methods specially adapted for bringing pharmaceutical products into particular physical or administering forms into the form of capsules or similar small containers for oral use into the form of telescopically engaged two-piece capsules
    • A61J3/074—Filling capsules; Related operations
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61J—CONTAINERS SPECIALLY ADAPTED FOR MEDICAL OR PHARMACEUTICAL PURPOSES; DEVICES OR METHODS SPECIALLY ADAPTED FOR BRINGING PHARMACEUTICAL PRODUCTS INTO PARTICULAR PHYSICAL OR ADMINISTERING FORMS; DEVICES FOR ADMINISTERING FOOD OR MEDICINES ORALLY; BABY COMFORTERS; DEVICES FOR RECEIVING SPITTLE
    • A61J3/00—Devices or methods specially adapted for bringing pharmaceutical products into particular physical or administering forms
    • A61J3/07—Devices or methods specially adapted for bringing pharmaceutical products into particular physical or administering forms into the form of capsules or similar small containers for oral use
    • A61J3/071—Devices or methods specially adapted for bringing pharmaceutical products into particular physical or administering forms into the form of capsules or similar small containers for oral use into the form of telescopically engaged two-piece capsules
    • A61J3/072—Sealing capsules, e.g. rendering them tamper-proof
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61J—CONTAINERS SPECIALLY ADAPTED FOR MEDICAL OR PHARMACEUTICAL PURPOSES; DEVICES OR METHODS SPECIALLY ADAPTED FOR BRINGING PHARMACEUTICAL PRODUCTS INTO PARTICULAR PHYSICAL OR ADMINISTERING FORMS; DEVICES FOR ADMINISTERING FOOD OR MEDICINES ORALLY; BABY COMFORTERS; DEVICES FOR RECEIVING SPITTLE
    • A61J2205/00—General identification or selection means
    • A61J2205/20—Colour codes
    • Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10—TECHNICAL SUBJECTS COVERED BY FORMER USPC
    • Y10S—TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10S53/00—Package making
    • Y10S53/90—Capsules

Abstract

Method and apparatus for encapsulating small articles such as medicines in caplet or cylindrical form are disclosed. Gelatin half capsules are formed on the pins (11) of pin blacks. ( 10) and are delivered to a station at which they are trimmed and fitted over the opposite ends of the product to be encapsulated. The capsule halves are first dried to a condition in which they have about 20 wt. % moisture and are thereafter press fitted over the ends of the caplets and allowed to dry to shrink fit tightly onto the caplets' making it virtually impossible to remove them from their gelatin coverings without leaving visible evidence of tampering.
The finished product has a smoother outer surface which lends itself to overprinting.
CA002141866A 1992-08-07 1993-08-06 Encapsulating equipment and method Expired - Lifetime CA2141866C (en)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US07/927,066 US5317849A (en) 1992-08-07 1992-08-07 Encapsulation equipment and method
US07/927,066 1992-08-07
PCT/US1993/007400 WO1994003365A1 (en) 1992-08-07 1993-08-06 Encapsulation equipment and method

Publications (2)

Publication Number Publication Date
CA2141866A1 true CA2141866A1 (en) 1994-02-17
CA2141866C CA2141866C (en) 2001-02-27

Family

ID=25454115

Family Applications (1)

Application Number Title Priority Date Filing Date
CA002141866A Expired - Lifetime CA2141866C (en) 1992-08-07 1993-08-06 Encapsulating equipment and method

Country Status (10)

Country Link
US (4) US5317849A (en)
EP (1) EP0653995B1 (en)
JP (1) JP3552719B2 (en)
KR (1) KR100294309B1 (en)
AT (1) ATE177696T1 (en)
CA (1) CA2141866C (en)
DE (1) DE69324018T2 (en)
DK (1) DK0653995T3 (en)
GR (1) GR3030303T3 (en)
WO (1) WO1994003365A1 (en)

Families Citing this family (66)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US6482516B1 (en) * 1993-07-20 2002-11-19 Banner Pharmacaps, Inc. Enrobed tablet
FI90627C (en) * 1992-07-31 1994-03-10 Leiras Oy Apparatus for providing a medicine rod with a jacket
US5317849A (en) * 1992-08-07 1994-06-07 Sauter Manufacturing Corporation Encapsulation equipment and method
US5415868A (en) * 1993-06-09 1995-05-16 L. Perrigo Company Caplets with gelatin cover and process for making same
US5442897A (en) * 1993-10-05 1995-08-22 Hauni Richmond, Inc. Method of and apparatus for making tubular envelopes
US5920562A (en) * 1996-11-22 1999-07-06 Sprint Communications Co. L.P. Systems and methods for providing enhanced services for telecommunication call
PT765150E (en) * 1994-06-16 2003-01-31 Warner Lambert Co METHOD AND APPARATUS FOR PRODUCING CLOSED SEALED CAPSULES
CA2205553C (en) * 1994-12-16 2009-04-07 Warner-Lambert Company Process for encapsulation of caplets in a capsule and solid dosage forms obtainable by such process
US6245350B1 (en) 1994-12-16 2001-06-12 Warner-Lambert Company Process for encapsulation of caplets in a capsule and solid dosage forms obtainable by such process
IT1278210B1 (en) * 1995-05-19 1997-11-17 Ima Spa AUTOMATIC MACHINE FOR PACKAGING TABLETS WITHIN JELLY CAPSULES
US6113945A (en) * 1996-02-26 2000-09-05 L. Perrigo Company Multi-colored medicament
US5824338A (en) * 1996-08-19 1998-10-20 L. Perrigo Company Caplet and gelatin covering therefor
US6669954B2 (en) 2000-01-25 2003-12-30 John R. Crison Controlled release of drugs
KR100721088B1 (en) 2000-04-26 2007-05-23 신에쓰 가가꾸 고교 가부시끼가이샤 Solid Formulation Coated by Film Coating Layer And Film Coating Agent
US6767200B2 (en) * 2001-09-28 2004-07-27 Mcneil-Ppc, Inc. Systems, methods and apparatuses for manufacturing dosage forms
US7217381B2 (en) * 2001-09-28 2007-05-15 Mcneil-Ppc, Inc. Systems, methods and apparatuses for manufacturing dosage forms
JP2005509605A (en) 2001-09-28 2005-04-14 マクニール−ピーピーシー・インコーポレイテッド A dosage form comprising an edible composition and an edible skin
US7122143B2 (en) * 2001-09-28 2006-10-17 Mcneil-Ppc, Inc. Methods for manufacturing dosage forms
US20040253312A1 (en) 2001-09-28 2004-12-16 Sowden Harry S. Immediate release dosage form comprising shell having openings therein
US7323192B2 (en) * 2001-09-28 2008-01-29 Mcneil-Ppc, Inc. Immediate release tablet
US6837696B2 (en) * 2001-09-28 2005-01-04 Mcneil-Ppc, Inc. Apparatus for manufacturing dosage forms
US7838026B2 (en) 2001-09-28 2010-11-23 Mcneil-Ppc, Inc. Burst-release polymer composition and dosage forms comprising the same
US6742646B2 (en) * 2001-09-28 2004-06-01 Mcneil-Ppc, Inc. Systems, methods and apparatuses for manufacturing dosage forms
US6982094B2 (en) 2001-09-28 2006-01-03 Mcneil-Ppc, Inc. Systems, methods and apparatuses for manufacturing dosage forms
US7169450B2 (en) 2002-05-15 2007-01-30 Mcneil-Ppc, Inc. Enrobed core
US6946156B2 (en) * 2002-05-15 2005-09-20 Mcneil-Ppc, Inc. Process for enrobing a core
US7807197B2 (en) * 2002-09-28 2010-10-05 Mcneil-Ppc, Inc. Composite dosage forms having an inlaid portion
RU2005108576A (en) 2002-09-28 2005-09-20 МакНЕЙЛ-ППС, ИНК. (US) POLYMERIC COMPOSITION AND CONTAINING ITS MEDICINAL FORMS
US20050074514A1 (en) * 2003-10-02 2005-04-07 Anderson Oliver B. Zero cycle molding systems, methods and apparatuses for manufacturing dosage forms
US8067029B2 (en) 2004-01-13 2011-11-29 Mcneil-Ppc, Inc. Rapidly disintegrating gelatinous coated tablets
US7879354B2 (en) 2004-01-13 2011-02-01 Mcneil-Ppc, Inc. Rapidly disintegrating gelatinous coated tablets
CA2499293C (en) * 2004-04-26 2014-05-06 Jeffrey Martin Danta Gelatin ribbon printing method and apparatus
KR20130115401A (en) * 2004-11-19 2013-10-21 글락소스미스클라인 엘엘씨 Pharmaceutical product
US8022032B2 (en) * 2004-11-19 2011-09-20 Smithkline Beecham Corporation Method for customized dispensing of variable dose drug combination products for individualizing of therapies
US7404708B2 (en) * 2004-12-07 2008-07-29 Mcneil-Ppc, Inc. System and process for providing at least one opening in dosage forms
US7530804B2 (en) * 2004-12-07 2009-05-12 Mcneil-Ppc, Inc. System and process for providing at least one opening in dosage forms
FR2881046A1 (en) * 2005-01-25 2006-07-28 7 Med Ind Sa Manufacturing method for a hormonal contraceptive tube in which a membrane reservoir is inserted in a holding tube, the reservoir is filled by injection, one end sealed, further filled and then the product polymerized
US8673352B2 (en) * 2005-04-15 2014-03-18 Mcneil-Ppc, Inc. Modified release dosage form
EA012998B1 (en) * 2005-11-18 2010-02-26 Глэксо Груп Лимитед Machine and method for pharmaceutical and pharmaceutical-like product assembly
DE602007008384D1 (en) * 2006-03-28 2010-09-23 Mcneil Ppc Inc FORM COATINGS WITH INCORRECT DOSAGE
EP2433621B1 (en) 2006-09-15 2013-05-01 Capsugel Belgium NV Rapidly disintegrating dosage form
US20090110724A1 (en) * 2007-10-31 2009-04-30 Everett Laboratories, Inc. Compositions and methods for treatment of pain
WO2012024360A2 (en) 2010-08-18 2012-02-23 Mcneil-Ppc, Inc. Tablet sleeve for improved performance
MX363959B (en) 2011-10-06 2019-04-09 Combocap Inc A method and apparatus for manufacturing a capsule.
CN104245635A (en) 2012-04-26 2014-12-24 宝洁公司 Articles for in-home composting and method of composting
CA2871218A1 (en) 2012-04-26 2013-10-31 The Procter & Gamble Company Articles for in-home composting
US9101546B2 (en) 2012-09-28 2015-08-11 Sci-Tech Centre Capsule for encapsulating a tablet
US9456987B2 (en) 2013-04-03 2016-10-04 Binutra, Inc. Capsule with internal diaphragm
EP3236993B1 (en) 2014-12-23 2023-09-13 Theriva Biologics, Inc. Methods and compositions for inhibiting or preventing adverse effects of oral antibiotics
WO2016157207A1 (en) * 2015-03-28 2016-10-06 Anand Goldie Auto head and pin bar assembly
WO2016210211A1 (en) 2015-06-25 2016-12-29 The Procter & Gamble Company Compositions for in-home waste management
US10583089B2 (en) 2016-07-19 2020-03-10 Johnson & Johnson Consumer Inc. Tablets having discontinuous coated regions
BR112019001076A8 (en) 2016-07-19 2022-08-09 Currahee Holding Company Inc DOSAGE FORM, MANUFACTURING METHOD OF A DOSAGE FORM AND APPARATUS FOR APPLYING A CIRCUMFERENTIAL BATCH COATED REGION ON A SURFACE OF A TABLET-FORMED SUBSTRATE
KR20200038506A (en) 2017-08-07 2020-04-13 핀치 테라퓨틱스, 인코포레이티드 Compositions and methods for maintaining and restoring healthy intestinal barrier
US11338020B2 (en) 2018-01-09 2022-05-24 Synthetic Biologics, Inc. Alkaline phosphatase agents for treatment of neurodevelopmental disorders
CA3094174A1 (en) 2018-03-20 2019-09-26 Synthetic Biologics, Inc. Alkaline phosphatase agents for treatment of radiation disorders
CN110028030B (en) * 2019-04-23 2021-05-04 浙江东合印刷包装有限公司 Printing machine capable of manually adding ink
US20220331378A1 (en) 2019-09-13 2022-10-20 Finch Therapeutics Holdings Llc Compositions and methods for treating autism spectrum disorder
WO2021077107A1 (en) 2019-10-18 2021-04-22 Crestovo Holdings Llc Compositions and methods for delivering a bacterial metabolite to a subject
US20210137791A1 (en) * 2019-11-11 2021-05-13 Joey R. Gonzales Capsule filler
WO2021097288A1 (en) 2019-11-15 2021-05-20 Finch Therapeutics Holdings Llc Compositions and methods for treating neurodegenerative diseases
WO2021142358A1 (en) 2020-01-10 2021-07-15 Finch Therapeutics Holdings Llc Compositions and methods for treating hepatic encephalopathy (he)
WO2021142353A1 (en) 2020-01-10 2021-07-15 Finch Therapeutics Holdings Llc Compositions and methods for treating hepatitis b (hbv) and hepatitis d (hdv)
WO2021142347A1 (en) 2020-01-10 2021-07-15 Finch Therapeutics Holdings Llc Compositions and methods for non-alcoholic steatohepatitis (nash)
WO2021202806A1 (en) 2020-03-31 2021-10-07 Finch Therapeutics Holdings Llc Compositions comprising non-viable fecal microbiota and methods of use thereof
WO2022178294A1 (en) 2021-02-19 2022-08-25 Finch Therapeutics Holdings Llc Compositions and methods for providing secondary bile acids to a subject

Family Cites Families (25)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US326578A (en) * 1885-09-22 Capsule-joining machine
US540538A (en) * 1895-06-04 Machine for dipping pills
US961936A (en) * 1909-01-09 1910-06-21 Arthur Colton Co Machine for making capsules.
US1787777A (en) * 1926-12-10 1931-01-06 Parke Davis & Co Capsule machine
US2299039A (en) * 1940-03-05 1942-10-13 Robert P Scherer Method of fabricating capsules
US2373721A (en) * 1942-08-08 1945-04-17 Atlantic Coast Fisheries Co Apparatus for coating
US2671245A (en) * 1949-02-03 1954-03-09 Lilly Co Eli Capsule machine
US2727473A (en) * 1951-05-04 1955-12-20 Merck & Co Inc Coating mechanism
US2936493A (en) * 1955-06-16 1960-05-17 Scherer Corp R P Method of making plastic capsules
US3078629A (en) * 1960-01-08 1963-02-26 Upjohn Co Method for sealing hard filled capsules
GB1054977A (en) * 1964-01-20
US3927195A (en) * 1974-01-31 1975-12-16 Lilly Industries Ltd Production of capsules
US4667498A (en) * 1984-06-29 1987-05-26 Sauter Manufacturing Corp. Method and apparatus of making gelatine capsule forming pins having a rounded locking groove
US4928840A (en) * 1986-02-25 1990-05-29 American Home Products Corporation Tamper proof encapsulated medicaments
KR900000254B1 (en) * 1986-05-12 1990-01-24 신에쯔까 가가꾸 고우교우 가부시끼가이샤 Process for the preparation of soft capsules and apparatus therefor
US4867983A (en) * 1987-02-20 1989-09-19 Mcneilab, Inc. Method for double dipping gelating coated caplets
US4921108A (en) * 1987-02-20 1990-05-01 Mcneilab, Inc. Apparatus for gelatin coating caplets
US4820524A (en) * 1987-02-20 1989-04-11 Mcneilab, Inc. Gelatin coated caplets and process for making same
US4936074A (en) * 1988-11-17 1990-06-26 D. M. Graham Laboratories, Inc. Process for preparing solid encapsulated medicament
US4965089A (en) * 1989-04-10 1990-10-23 Sauter Manufacturing Corp. Method and apparatus for the gelatin coating of caplets
US5146730A (en) * 1989-09-20 1992-09-15 Banner Gelatin Products Corp. Film-enrobed unitary-core medicament and the like
US5081822A (en) * 1990-02-01 1992-01-21 Warner-Lambert Company Automatic caplet filler
JP2740566B2 (en) * 1990-04-26 1998-04-15 日本エランコ株式会社 Capsule filling equipment
US5317849A (en) * 1992-08-07 1994-06-07 Sauter Manufacturing Corporation Encapsulation equipment and method
US5415868A (en) * 1993-06-09 1995-05-16 L. Perrigo Company Caplets with gelatin cover and process for making same

Also Published As

Publication number Publication date
ATE177696T1 (en) 1999-04-15
JPH08500073A (en) 1996-01-09
EP0653995A4 (en) 1995-11-22
WO1994003365A1 (en) 1994-02-17
DK0653995T3 (en) 1999-09-27
DE69324018D1 (en) 1999-04-22
KR100294309B1 (en) 2001-11-22
EP0653995A1 (en) 1995-05-24
US5609010A (en) 1997-03-11
CA2141866C (en) 2001-02-27
US5317849A (en) 1994-06-07
US5795588A (en) 1998-08-18
US5511361A (en) 1996-04-30
DE69324018T2 (en) 1999-08-12
GR3030303T3 (en) 1999-09-30
JP3552719B2 (en) 2004-08-11
EP0653995B1 (en) 1999-03-17

Similar Documents

Publication Publication Date Title
CA2141866A1 (en) Encapsulating equipment and method
AU620829B2 (en) Method for double dipping gelatin coated caplets
GB2124551B (en) Pasteurizable and cook-in shrink films and their production
CA2050911A1 (en) Encapsulation process and products therefrom
CA2036707A1 (en) Improved coated medicaments and apparatus and methods for making the same
KR0140854B1 (en) Film enrobed unitary core medicament and the like
GB9021061D0 (en) Encapsulating method and products containing encapsulated material
HUT70848A (en) 1-aminoethyl-indol derivatives, process for production thereof and pharmaceutical compositions comprising them
HUP9603198A3 (en) Confectionery product and process for their production
NZ220827A (en) Comestible ingredient encapsulated in polymeric material; contains deoiled lecithin
US5460824A (en) Method for the preparation of an encapsulated medicament
AU2100688A (en) Edible fat-containing product and process for preparing same
AU2480388A (en) Process for manufacturing particle boards and similar, and suitable twin-belt presses
HUP9900636A3 (en) Confectionery product and process for their production
HUP9900052A3 (en) Pharmaceutical pellet formulation and process for producing it
GB2126070B (en) Method for manufacturing a jelly confectionery coated with chocolate and a product thereof
EP0711116A4 (en) Improved chewing gum and candy products
CA2231431A1 (en) Method for marking objects and objects being marked with such method
IT1237771B (en) PROCESS FOR THE CREATION OF A COSMETIC PRODUCT WITH POWDERS OF MORE COLORS AND / OR DIFFERENT CHARACTERISTICS.
AU5491786A (en) Apparatus and method for encapsulating sweets
GB2114865B (en) Flowable dried aromatic plant product and process for making same
HU910040D0 (en) Process for the production of granulates containing derivatives protected from decomposition in the rumen of ruminants
GB9501017D0 (en) Microencapsulation process and product
HUT58102A (en) Process for producing quinolidine derivatives and pharmaceutical compositions comprising such compounds
AU3395189A (en) Automated process for the preparation of an edible fat- containing product and apparatus for carrying out such a process

Legal Events

Date Code Title Description
EEER Examination request