CA2163425A1 - Method and apparatus for measuring flow using frequency-dispersive techniques - Google Patents

Method and apparatus for measuring flow using frequency-dispersive techniques

Info

Publication number
CA2163425A1
CA2163425A1 CA002163425A CA2163425A CA2163425A1 CA 2163425 A1 CA2163425 A1 CA 2163425A1 CA 002163425 A CA002163425 A CA 002163425A CA 2163425 A CA2163425 A CA 2163425A CA 2163425 A1 CA2163425 A1 CA 2163425A1
Authority
CA
Canada
Prior art keywords
signal
frequency
fluid
flow
heat
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Granted
Application number
CA002163425A
Other languages
French (fr)
Other versions
CA2163425C (en
Inventor
Robert C. Dixon
Theodore R. Lapp
Donald E. Bobo, Jr.
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Edwards Lifesciences Corp
Original Assignee
Robert C. Dixon
Theodore R. Lapp
Donald E. Bobo, Jr.
Baxter International Inc.
Edwards Lifesciences Corporation
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Robert C. Dixon, Theodore R. Lapp, Donald E. Bobo, Jr., Baxter International Inc., Edwards Lifesciences Corporation filed Critical Robert C. Dixon
Publication of CA2163425A1 publication Critical patent/CA2163425A1/en
Application granted granted Critical
Publication of CA2163425C publication Critical patent/CA2163425C/en
Anticipated expiration legal-status Critical
Expired - Lifetime legal-status Critical Current

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B5/00—Measuring for diagnostic purposes; Identification of persons
    • A61B5/02—Detecting, measuring or recording pulse, heart rate, blood pressure or blood flow; Combined pulse/heart-rate/blood pressure determination; Evaluating a cardiovascular condition not otherwise provided for, e.g. using combinations of techniques provided for in this group with electrocardiography or electroauscultation; Heart catheters for measuring blood pressure
    • A61B5/026—Measuring blood flow
    • A61B5/0275—Measuring blood flow using tracers, e.g. dye dilution
    • A61B5/028—Measuring blood flow using tracers, e.g. dye dilution by thermo-dilution
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B5/00—Measuring for diagnostic purposes; Identification of persons
    • A61B5/72—Signal processing specially adapted for physiological signals or for diagnostic purposes
    • A61B5/7232—Signal processing specially adapted for physiological signals or for diagnostic purposes involving compression of the physiological signal, e.g. to extend the signal recording period
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B5/00—Measuring for diagnostic purposes; Identification of persons
    • A61B5/72—Signal processing specially adapted for physiological signals or for diagnostic purposes
    • A61B5/7235—Details of waveform analysis
    • A61B5/7253—Details of waveform analysis characterised by using transforms
    • A61B5/7257—Details of waveform analysis characterised by using transforms using Fourier transforms

Abstract

A system for measuring fluid flow within a conduit, such as blood flow from the heart, includes a heating element that is driven so as to apply heat to the fluid at an upstream position as a series of periodic heat signals. A temperature sensor located downstream measures a local temperature of the fluid and generates an electrical fluid temperature signal corresponding to the local temperature. This signal is then applied to a dispersive filter, which outputs a pulse-like signal in the presence of each periodic heat signal. Fluid flow is then calculated by a processor as a function of the area under an estimated impulse response curve for the channel in which the fluid flows. Each periodic heat signal is preferably sinusoidal and has an instantaneous frequency that varies substantially continuously between a first frequency and a second frequency over a pre-determined active input signal period. In a preferred embodiment, the frequency varies linearly between a first and a second frequency over a predetermined time period. The output signal from the filter, which is itself an estimate of the channel impulse response, is preferably integrated in order to provide a parameter estimate that is inversely proportional to flow. The corresponding method of measuring fluid flow using a frequency-swept input heat signal and matched dispersive filtering is included.
CA002163425A 1993-06-04 1994-05-31 Method and apparatus for measuring flow using frequency-dispersive techniques Expired - Lifetime CA2163425C (en)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US08/071,838 US5357967A (en) 1993-06-04 1993-06-04 Method and apparatus for measuring flow using frequency-dispersive techniques
US08/071,838 1993-06-04
PCT/US1994/006138 WO1994028788A1 (en) 1993-06-04 1994-05-31 Method and apparatus for measuring flow using frequency-dispersive techniques

Publications (2)

Publication Number Publication Date
CA2163425A1 true CA2163425A1 (en) 1994-12-22
CA2163425C CA2163425C (en) 2004-07-27

Family

ID=22103916

Family Applications (1)

Application Number Title Priority Date Filing Date
CA002163425A Expired - Lifetime CA2163425C (en) 1993-06-04 1994-05-31 Method and apparatus for measuring flow using frequency-dispersive techniques

Country Status (6)

Country Link
US (1) US5357967A (en)
EP (1) EP0701413B1 (en)
JP (1) JP3456705B2 (en)
CA (1) CA2163425C (en)
DE (1) DE69412093T2 (en)
WO (1) WO1994028788A1 (en)

Families Citing this family (20)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5598847A (en) * 1994-12-28 1997-02-04 Pacesetter, Inc. Implantable flow sensor apparatus and method
US5687733A (en) * 1995-10-26 1997-11-18 Baxter International Inc. System and method for estimating cardiac output
IT1287889B1 (en) 1996-01-19 1998-08-26 Biomedin Srl DEVICE WITH SMALL THERMAL CAPACITY FOR PORTABLE PRECISION SPIROMETRY AND FOR OTHER APPLICATIONS
US5954659A (en) * 1996-02-16 1999-09-21 Curley; Michael G. Method and apparatus for invasively measuring cardiac output by detecting temperature differences of blood heated by radiation
US6010457A (en) * 1996-03-15 2000-01-04 Pmv Medical Pty Ltd Non-invasive determination of aortic flow velocity waveforms
US5971935A (en) * 1998-05-01 1999-10-26 Baxter International Inc. Methods and apparatus for reducing noise in systems using thermistor catheters to measure biological functions
US6726647B1 (en) * 1998-10-23 2004-04-27 Gambro Ab Method and device for measuring access flow
US6371923B1 (en) * 1999-12-07 2002-04-16 Edwards Lifesciences Corporation Time-domain system and method for relaxation measurement and estimation of indicator dilution for continuous estimation and display of cardiac ejection fraction and end diastolic volume
US6384651B1 (en) * 2000-03-28 2002-05-07 Intel Corporation Method of generating a signal with controlled duty-cycle and pseudo-random spectrum
US20020136264A1 (en) * 2001-03-20 2002-09-26 Herleikson Earl C. Spread spectrum measurement device
WO2003071384A2 (en) * 2002-02-15 2003-08-28 Eunoe, Inc. Systems and methods for flow detection and measurement in csf shunts
FR2836831B1 (en) * 2002-03-07 2004-06-25 Centre Nat Rech Scient COMBINATION OF CHEMOTHERAPY AND ANTISENSE OF DNA DEMETHYLASE
AU2004208554B2 (en) * 2003-01-28 2008-11-06 Gambro Lundia Ab An apparatus and method for monitoring a vascular access of a patient
JP4223915B2 (en) * 2003-10-01 2009-02-12 株式会社日立製作所 Thermal flow meter and control system
EP1691862A1 (en) * 2003-11-20 2006-08-23 Gambro Lundia AB Method, apparatus and software program for measurement of a parameter relating to a heart-lung system of a mammal.
EP1691885B1 (en) * 2003-12-11 2014-04-02 Gambro Lundia AB Switching device and apparatus for controlling flow of a fluid
ES2348407T3 (en) * 2005-05-18 2010-12-03 Gambro Lundia Ab APPLIANCE TO CONTROL THE BLOOD FLOW IN AN EXTRACORPORE CIRCUIT.
TW200835463A (en) * 2006-12-27 2008-09-01 Koninkl Philips Electronics Nv Method and apparatus for measuring fluid properties, including pH
US8353864B2 (en) 2009-02-18 2013-01-15 Davis David L Low cost disposable infusion pump
US8197235B2 (en) 2009-02-18 2012-06-12 Davis David L Infusion pump with integrated permanent magnet

Family Cites Families (9)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4236527A (en) * 1978-10-20 1980-12-02 Massachusetts General Hospital Cardiac output detection by multiple frequency thermodilution
US4326527A (en) * 1980-05-27 1982-04-27 Kimberly-Clark Corporation Microwave heat setting of tampon
US4402230A (en) * 1981-07-17 1983-09-06 Raptis Apostolos C Method and apparatus for measuring flow velocity using matched filters
US4502488A (en) * 1983-01-13 1985-03-05 Allied Corporation Injection system
US4507974A (en) * 1983-04-21 1985-04-02 The Board Of Trustees Of The Leland Stanford Jr. University Method and apparatus for measuring flow
US4656642A (en) * 1984-04-18 1987-04-07 Sanders Associates, Inc. Spread-spectrum detection system for a multi-element antenna
US4739186A (en) * 1986-08-18 1988-04-19 Hughes Aircraft Company Frequency-selectable pulsed-sinusoid generation system
US5146414A (en) * 1990-04-18 1992-09-08 Interflo Medical, Inc. Method and apparatus for continuously measuring volumetric flow
US5217019A (en) * 1991-12-27 1993-06-08 Abbott Laboratories Apparatus and method for continuously monitoring cardiac output

Also Published As

Publication number Publication date
EP0701413A1 (en) 1996-03-20
WO1994028788A1 (en) 1994-12-22
DE69412093D1 (en) 1998-09-03
CA2163425C (en) 2004-07-27
EP0701413B1 (en) 1998-07-29
US5357967A (en) 1994-10-25
JPH08511446A (en) 1996-12-03
DE69412093T2 (en) 1999-04-22
JP3456705B2 (en) 2003-10-14

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MKEX Expiry

Effective date: 20140602