CA2173841A1 - Ultrasonic spectral contrast imaging - Google Patents

Ultrasonic spectral contrast imaging

Info

Publication number
CA2173841A1
CA2173841A1 CA002173841A CA2173841A CA2173841A1 CA 2173841 A1 CA2173841 A1 CA 2173841A1 CA 002173841 A CA002173841 A CA 002173841A CA 2173841 A CA2173841 A CA 2173841A CA 2173841 A1 CA2173841 A1 CA 2173841A1
Authority
CA
Canada
Prior art keywords
contrast
imaging
contrast imaging
contrast agents
spectral contrast
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Granted
Application number
CA002173841A
Other languages
French (fr)
Other versions
CA2173841C (en
Inventor
Marcel Arditi
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Bracco Suisse SA
Original Assignee
Marcel Arditi
Bracco Research S.A.
Bracco Suisse S.A.
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Marcel Arditi, Bracco Research S.A., Bracco Suisse S.A. filed Critical Marcel Arditi
Publication of CA2173841A1 publication Critical patent/CA2173841A1/en
Application granted granted Critical
Publication of CA2173841C publication Critical patent/CA2173841C/en
Anticipated expiration legal-status Critical
Expired - Fee Related legal-status Critical Current

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B8/00—Diagnosis using ultrasonic, sonic or infrasonic waves
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B8/00—Diagnosis using ultrasonic, sonic or infrasonic waves
    • A61B8/48—Diagnostic techniques
    • A61B8/481—Diagnostic techniques involving the use of contrast agent, e.g. microbubbles introduced into the bloodstream
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01S—RADIO DIRECTION-FINDING; RADIO NAVIGATION; DETERMINING DISTANCE OR VELOCITY BY USE OF RADIO WAVES; LOCATING OR PRESENCE-DETECTING BY USE OF THE REFLECTION OR RERADIATION OF RADIO WAVES; ANALOGOUS ARRANGEMENTS USING OTHER WAVES
    • G01S7/00—Details of systems according to groups G01S13/00, G01S15/00, G01S17/00
    • G01S7/52—Details of systems according to groups G01S13/00, G01S15/00, G01S17/00 of systems according to group G01S15/00
    • G01S7/52017—Details of systems according to groups G01S13/00, G01S15/00, G01S17/00 of systems according to group G01S15/00 particularly adapted to short-range imaging
    • G01S7/52023—Details of receivers
    • G01S7/52036—Details of receivers using analysis of echo signal for target characterisation
    • G01S7/52038—Details of receivers using analysis of echo signal for target characterisation involving non-linear properties of the propagation medium or of the reflective target
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01S—RADIO DIRECTION-FINDING; RADIO NAVIGATION; DETERMINING DISTANCE OR VELOCITY BY USE OF RADIO WAVES; LOCATING OR PRESENCE-DETECTING BY USE OF THE REFLECTION OR RERADIATION OF RADIO WAVES; ANALOGOUS ARRANGEMENTS USING OTHER WAVES
    • G01S7/00—Details of systems according to groups G01S13/00, G01S15/00, G01S17/00
    • G01S7/52—Details of systems according to groups G01S13/00, G01S15/00, G01S17/00 of systems according to group G01S15/00
    • G01S7/52017—Details of systems according to groups G01S13/00, G01S15/00, G01S17/00 of systems according to group G01S15/00 particularly adapted to short-range imaging
    • G01S7/52023—Details of receivers
    • G01S7/52036—Details of receivers using analysis of echo signal for target characterisation
    • G01S7/52038—Details of receivers using analysis of echo signal for target characterisation involving non-linear properties of the propagation medium or of the reflective target
    • G01S7/52039—Details of receivers using analysis of echo signal for target characterisation involving non-linear properties of the propagation medium or of the reflective target exploiting the non-linear response of a contrast enhancer, e.g. a contrast agent

Abstract

This invention is applicable to the electronic circuits found in echographic imaging instruments, such as those used for medical diagnosis. Its implementation requires the injection of specific contrast agents in the body, or more generally in the region to be imaged. The underlying principle of the new imaging proposed is based on use of frequency dependent bahaviour of the ultrasound contrast agents containing microbubbles. In essence, these imaging principles exploit certain physical "signatures" of the contrast agent responses, allowing increased contrast with respect to tissue background. This contrast enhancement is much larger than what is determined from direct echo amplitude monitoring.
CA002173841A 1994-09-22 1995-09-21 Ultrasonic spectral contrast imaging Expired - Fee Related CA2173841C (en)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
EP94810546 1994-09-22
EP94810546.5 1994-09-22
PCT/IB1995/000773 WO1996009002A1 (en) 1994-09-22 1995-09-21 Ultrasonic spectral contrast imaging

Publications (2)

Publication Number Publication Date
CA2173841A1 true CA2173841A1 (en) 1996-03-28
CA2173841C CA2173841C (en) 2007-01-23

Family

ID=8218312

Family Applications (1)

Application Number Title Priority Date Filing Date
CA002173841A Expired - Fee Related CA2173841C (en) 1994-09-22 1995-09-21 Ultrasonic spectral contrast imaging

Country Status (17)

Country Link
US (1) US5526816A (en)
EP (1) EP0730433B1 (en)
JP (1) JP3604696B2 (en)
KR (1) KR100380227B1 (en)
CN (1) CN1120695C (en)
AT (1) ATE266966T1 (en)
AU (1) AU688116B2 (en)
CA (1) CA2173841C (en)
CZ (1) CZ290552B6 (en)
DE (1) DE69533059T2 (en)
FI (1) FI107875B (en)
IL (1) IL115363A (en)
MX (1) MX9601754A (en)
NO (1) NO962068L (en)
NZ (1) NZ292253A (en)
WO (1) WO1996009002A1 (en)
ZA (1) ZA957999B (en)

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Also Published As

Publication number Publication date
WO1996009002A1 (en) 1996-03-28
DE69533059D1 (en) 2004-06-24
NO962068D0 (en) 1996-05-21
ATE266966T1 (en) 2004-06-15
FI962143A (en) 1996-05-21
EP0730433A1 (en) 1996-09-11
CZ133196A3 (en) 1996-08-14
EP0730433B1 (en) 2004-05-19
CA2173841C (en) 2007-01-23
MX9601754A (en) 1998-01-31
NO962068L (en) 1996-05-21
IL115363A (en) 2000-01-31
IL115363A0 (en) 1995-12-31
JPH09505761A (en) 1997-06-10
AU688116B2 (en) 1998-03-05
AU3397995A (en) 1996-04-09
CN1120695C (en) 2003-09-10
JP3604696B2 (en) 2004-12-22
CZ290552B6 (en) 2002-08-14
US5526816A (en) 1996-06-18
DE69533059T2 (en) 2005-05-12
KR960705504A (en) 1996-11-08
FI107875B (en) 2001-10-31
ZA957999B (en) 1996-04-18
FI962143A0 (en) 1996-05-21
NZ292253A (en) 1997-05-26
CN1135712A (en) 1996-11-13
KR100380227B1 (en) 2003-07-22

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