CA2183462A1 - Intraocular lens microcartridge - Google Patents
Intraocular lens microcartridgeInfo
- Publication number
- CA2183462A1 CA2183462A1 CA002183462A CA2183462A CA2183462A1 CA 2183462 A1 CA2183462 A1 CA 2183462A1 CA 002183462 A CA002183462 A CA 002183462A CA 2183462 A CA2183462 A CA 2183462A CA 2183462 A1 CA2183462 A1 CA 2183462A1
- Authority
- CA
- Canada
- Prior art keywords
- lens
- microcartridge
- passageway
- holder
- lens microcartridge
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Abandoned
Links
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
- A61B17/00—Surgical instruments, devices or methods, e.g. tourniquets
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61F—FILTERS IMPLANTABLE INTO BLOOD VESSELS; PROSTHESES; DEVICES PROVIDING PATENCY TO, OR PREVENTING COLLAPSING OF, TUBULAR STRUCTURES OF THE BODY, e.g. STENTS; ORTHOPAEDIC, NURSING OR CONTRACEPTIVE DEVICES; FOMENTATION; TREATMENT OR PROTECTION OF EYES OR EARS; BANDAGES, DRESSINGS OR ABSORBENT PADS; FIRST-AID KITS
- A61F2/00—Filters implantable into blood vessels; Prostheses, i.e. artificial substitutes or replacements for parts of the body; Appliances for connecting them with the body; Devices providing patency to, or preventing collapsing of, tubular structures of the body, e.g. stents
- A61F2/02—Prostheses implantable into the body
- A61F2/14—Eye parts, e.g. lenses, corneal implants; Implanting instruments specially adapted therefor; Artificial eyes
- A61F2/16—Intraocular lenses
- A61F2/1662—Instruments for inserting intraocular lenses into the eye
- A61F2/1664—Instruments for inserting intraocular lenses into the eye for manual insertion during surgery, e.g. forceps-like instruments
Abstract
This invention is a surgical device (10) for implantation of de-formable intraocular lens (54) into the eye through a relatively small incision made in the ocular tissue including a holder (12) with re-ceiver (13) for a lens holder: a lens holder (12) for a surgical device for implantation of deformable intraoc-ular lens (54) into the eye including a split tubular member (12) having a fixed tubular portion (70), and a moveable tubular portion (72) con-nected together at a hinge (82): and a method for implantation of de-formable intraocular lens into the eye using the above described sur-gical devices.
Description
WO 95122287 PCIIUS95/~2027 INTRAOCULAR LENS MICROCARTRIDGE
RELATED APPLICATION(S) TtTis application is a in part application of U.S. patent aMlication SeriaTT No. 07/953,251 filed on September 30, 1992, now ` ' ~ ' F[ELD OF TIIE INVEN~ON
This invention relates to an improved l.l;.,lT~Lfi~b_ for use with devices for the surgical ~ , ' of d.F~,TI ' ' intraocular lenses into the eye.
I~ACKGROUND OF THE INVENTION
Intraocular lenses have gained wide acceptance in l . '. of human crystaTline lenses after a variety of cataract removal procedures. The human crystalline lens is generalTly recognized to be a i . structure having a thickness of about five (5) --i11;-- t--` and a diameter of about nine (9) '-T' ' The lens is suspended behind the irTs by zonula fibers which connect ~VO 95122287 PC~T~U59SI~)21127 2 1 ~3462 the lens to the ciliary body. A lens capsule surrounds the lens, the front portion of the capsule being commonly known as the anterior capsule and the back portion commonly known as the posterior capsule.
Numerous procedures for the removal of cataracts have been developed 5 in which the lens is removed from the eye and replaced by an artificial lens implant. The extraction procedure may generally be ~ ~ ' as;
(in which the lens is removed together with the lens capsule) and ~ l r- 'U~
(in which the anterior capsule is removed with the lens, and the posterior capsule is left intact).
Since Ridley implanted the first artificial lens in about 1949, the problems associated with cataract extraction and lens ' have received a great deal of attention from ~rl ' ' - surgeons. Various types of artificial lenses have been proposed, and a~ ul surgical procedures have been developed which strive to reduce patient discomfort and to reduce p~ u~.dL;~
s ~-~r Reference is made in this connection to ~ ~ r ' I by N. Jaffe et al.; 'History of Intraocular Implants~ by D.P. Choyce (Annals of C~' ' ' ' ,~, October lg73); U.S. Patent No. 4,251,887 issued to Anis on February 24, 1981; U.S. Patent No. 4,092,743 issued to Kelman on November 8, 1977; ~rc~n~r~iCOn of Flexible Posterior Chamber Implants", presented at the American Intraocular Implant Society Symposium April 23, 1982, by Charles Berkert, M.D.; and "the Simcoe Posterior Lens~ (Cilco, Inc. 1980); U.S. Patent No. 4,573,998 issued to Mazzocco on March 4, 1986, and U.S. patent application Ser. No. 400,605 for "Improved Fixation System for Intraocular Lens Structures", filed July 22, 1982, U.S. Patent No. 4,702,244 issued to Mazzocco on October 27, 1987; and U.S. Patent No. 4,715,373 issued to Mazzocco et al.
on December 29, 1987, which disclosures are hereby i.~ ,. ' by reference.
-'O 9~';/222~7 P~:T~ITS~5/(12(~7 . r~ 21~3~46.?
Of particular interest in the context of the present invention is the d.,~.~ of surgical techniques requiring relatively small incisions in the ocular tissue for the removal of cataracts as disclosed in U.S. Patent No.
4,002,16g and U.S. Patent No. 3,996,935. A number of skilled artisans have disclosed intraocular lens structures . , ~, an optical wne portion generally made of rigid materials such as glass or plastics suitable for optical uæ.
However, one of the principal d;~i~_ - of the ~ .. ' rigid intraocular lens is that .' of the lens requires large incisions in the ocular tissue. This type of surgical procedure leads to a relatively high 10 l . ' - rate, among other disadvantages. For instance, the serious dangers asseciated with .' of a rigid lens structure include increased risk of infection, retinal ~ r ..~, and laceration of the oeular tissue, ~ i.,ul.ulr with respect to the pupil.
~1 ." 1, '~, those skilled in the art have re~ognized a significant need for surgical tools for .' of d~ intraocular lens struetures whieh afford the eliniea~ advantag of using relatively small incision teehniqu, whieh previde a safer and more convenient surgical procedure. In partieular, those skilled in the art of ~I~ f, " ", .1,1. intraocular lenses and methods and devices for . ' have also recognized a signifieant need for surgical tools whieh do not require widening of the wound made in the ocular tissue during or after , ' but will deform the intraocular lens to a ~ t~ - ' cross section in a strased state and which allow the ~r~ '' I ' surgeon to inspeet the lens prior to ,' without l , ' in the eye. The present invention T~ulfills these needs.
The present invention was derived by improving the methods and devices in the above-identifled patents, specifically the methods of U.S. Patent No.
4,573,998 and the devices of U.S. Patent No. 4,702,244.
WO 95/222X / pCrll 1~951~2027 ~ . ! 2 1 ~ 3 ~
SUMMARY OF TISE INVENTION
An object of the present invention is to provide an improved ~LliJl!~_ for use with devices for surgical r~ ' " of J~'u. ''-intraocular lenses.
Another object of the present invention is to provide an improved lens ~tlirigv comprising a lens holding portion and nozzle having a through bore with a pair of opposed grcovesa lens holding portion in covice including a lens holder, which can be loaded with a d~ful ' ' intraocular lens, and then inserted into a holder having means for implanting the lens.
A further object of the present invention is to provide a surgical device including a lens holder define by a ~ lid~_ comprising a lens holding portion in ~ ' with a nozzie for implanting the lens.
A still further object of the present invention is to provide a lens holding ~ L,i i~,_ for receiving a lens comprising a split tubular member having a 15 fixed porlion with an extension, and a moveable portion with an extension foropnung and closing the ~llidg_, which extensions prevent rotation between the I u~I.i~it,_ and holder when installed in the holder.
An even further object of the present invention is to provide a lens holding 1..;_1~1l;~_ having a noz~ie provided with slots for rotating the lens as it exits the noz~ie.
An object of the present invention is to provide a surgical device including a lens holder and a holder for the lens holder, the holder comprising a receiverfor the lens holder and a plunger for inserting the lens.
Another object of the present invention is to provide a holder defined by a cylindricai tubular member with an opening through the wail of the tubular member defining a receiver for the lens holder, and a piunger having a tip for contacting with and moving a lens contained in the lens holder.
WO ~CJ22287 PCT1115~5~02(12 ~
2 1 ~3~ 62 ~ . ~ . i "
s A further object of the present invention is to provide a plunger with a faceted tip that provides clearance for a trailing haptic in a ~ r through thc lens holder during the . ' process to prevent damage to the trailing haptic.
An even further object of the present invention is to provide a plunger having a tip with a concave conicai surface at the tip thereof for grabbing the lens during the .' process.
An object of the present invention is to provide improved methods of implanting d~fu. ' ' intraocuiar lenses;
Another object of the present invention is to provide a method including loading a ~ in~-t~ cular lens into a lens holder having an . ' nozzie, L ' ,, the intraocular lens within the lens holder, and implanting the lens into the eye.
The present invention concerns a system including methods and devices 15 for . ' of intraocular lenses into the eye.
The surgicai device according to the present invention includes the ' of a lens holder and a holder for the lens holder. The preferred lens holder comprises the ' of a lens receiYer and an . ' nozzle.
The lens receiver is preferably defined by a ..;~.uwL-;~i~ comprising a split 20 tubular member having a fixed tubular portion with an extension connected to a moveable tubular portion with an extension at a hinge. This ~nnf g ' ailows the ~l~;Jb- to be opened to accept a ~iLfu~ bl., intraocular lens, and closed to condense the lens into the p~ . The split tubular portion is connected to a nozzle with a continuous ~ ~6-~ passing through the tubular 25 member and the nozzle.
~'(~ 95~222X7 PCTII.IS951~2U27 The lens holder is inserted into a holder having means for driving or 'A ~ " ,, the lens from the lens holder into the eye. In the preferred t, the holder is proYided with a plunger for driving the lens from the lens holder into the eye. Purther, the holder is configured to receive a S ~ui ig having a nozzle.
The preferred holder includes means to prevent the ~uLlidg_ from rotating witbin the holder, and means for preventing the plungN from rotating within the holder. The means for preventing rotation of the IIU~ within the holder can be define by providing the . .~ lg. with one or more extensions that cooperate with the opening of the receiver of the holder to prevent rotation. The means for preventing the plunger from rotating within the holder can be defined by providing the plunger and a sleeve within the holder with a particular cross ' shape that prevents rotation, for example, a half-circle shape.
The preferred holder includes a plunger with a threaded cap with a threaded sleeve of the holder body for dialing the plunger forward withinthe holder for precise and accurate movement of the lens during the , ' process. The holder is configured so that the plunger can be moved a IJla~ ' ' ' distance by sliding motion within the holder body followed by ~ of the threaded cap of the plunger with the threaded sleeve of the holder body to continue the forward progress of the plunger tip.
The preferred plunger tip is defined by a faceted tip having various surfaces for moving and . ' ~ the lens from the lens holder and within the eye. The tip is designed to provide a clearance between the tip and the inner surface of the ~_wa,~ through lens holder to ~ ' the trailing haptic and prevent damage thereto. Once the lens is inserted into the eye, the tip can be used to push and rotated the lens into proper position within the eye.
~ WO !~5122287 PCTll~ 5/02(~2~
21 ~3462 A method according to the present invention includes lubricating the surface of a d~fw,....blc intraocular lens with a surgically compatible lubricant, and loading the lens into a ~ I~Llid~c in the opened position. The owl.iJg_ is closed while ~ ' _ the lens by a folding action into a S shape so that it can be forced through the p~ in the ~" The uwl-iJb_ is inserted into the holder with the plunger retracted.
The plunger is moved forward in a sliding manner by pushing the plunger forward while holding the hold body still, This action forces the lens from thetubular member portion of the ~ iJg_ into the nozzle portion. At this 10 point the threads of the threaded end cap of the plunger engage with the threads of the threaded sleeve. The threaded end cap i5 rotate slightly to engage the threads. The device is now ready for the ,' process.
The nozzle of the ...~ ,iJb_ is placed through a small incision in the eye. The threaded end cap of the plunger is rotated or dialed to further advanceIS the lens forward through the nozzle and into the cye. The threaded end cap isfurther dialed to e~pos~d the tip of the plunger within the eye and push the lens into position. The tip can be used to also rotate the lens within the eye for positioning of the haptics.
BRlEF DESCRIPIION OF THE DRAWINGS
Figure I is a ~.~Li~'~, view of one ~ ~ of device according to the prescnt invention with a lens holding ...;_ ~h~ridgG positioned in the device for . of <1 f~ lr lens structures for placement in the eye.
Figure 2 is a pe. .~liv~ view of the surgical device depicted in Figure I
with the plunger retracted, and with the lens holding, ~I-;dg~ removed.
Figure 3 is a side view of the device depicted in Figure 2, with the plunger in the e~dended position.
WC) 9~122287 PCT111595102027 o ;/i.`.j.~. ;~ 2i~3~62 Figure 4 is a side elevationai view of the device shown in Figure 1.
Figure S is a detailed ~.~r G,i~ cross-sectionai view of the device shown in Figure 4.
Figure 6 is a dehiled transverse cross-sectionai view of the device, as S indicated in Figure 5.
Figure 7 is a det~iled end view of the device, as indicated in Figure 5.
Figure 8 is an enlarged dehiled left side elevational view of the tip of the plunger in the spaciai orienhtion as shown in Figure 1.
Figure 9 is an eniarged det~iled end view of the tip shown in Figure 8.
Figure 10 is an enlarged dehiled top planar view of the tip of the plunger.
Figure 11 is an enlarged dehile~i right side elevationai view of the tip of the plunger in the spacial n~ q~illn, as shown in Figure 4.
Figure 12 is an eniarged dehiled bottom view of the tip of the plunger in the spacial ~ , as shown in Figure 1.
Figure 13 is a ~,~ view of a lens for use in the present invention.
Figurc 14 is a ~l~t~t;~, view of another type of lens for use in the present invention.
Figure 15 is a side view of the lens shown in Figure 13.
Figure 16 is a ~.~Li~ view of the lens holding ~ ~L~ ,_ in the 20open position to allow a lens to be loaded therein.
Figure 16A is another perspective view of the lens holding L~ C
in the open position.
Figure 17 is a rear end elevationai view of the lens holding ~Llhl~
in the open position.
Figure l8 is a front end elevational view of the lens holding ,,,;~I~L i~L_ in the open position.
Figure 19 is a rear end elevationai view of the lens holding l..._lU~ Ll id~,_ in the closed position.
~ W~ 9~1222#7 PCT/11595~(~2l)27 2 1 S 3 '~
Figure 20 is a front end elevationai view of the lens holding ".~.~I.id~,_ in the closed pOSitiOn.
Figure 20A is a detailed end view of the nozzle showing three (3) slots of different length equaily spaced about the e;., r _ of the tip.
Figure 20B is a det~iled pc.~iv~; view of the tip showing the three (3) slots of different length.
Figure 20C is a detailed side view showing the beveled tip.
Figure 2~ is a top planar view of the lens hoiding l.; '~_ in the oi~en position.
10Figure 22 is a side elevationai view of the lens holding ~ g_ in the closed i)osition.
Figure 23 is a rear end elevationai view of the lens holding u~LI;db~
in the closed position.
Figure 24 is a broicen away side view of the device showing the lens 15 holding ~ b- in ' ' . to the plunger in the retracted position.
Figure 25 is a broken away side view of the device showing the lens holding I-;~i~ in r~ . to the plunger in a partiaily extended position.
Figure 26 is a broken away side view of the device showing the lens 20 holding ' ~I-; ig_ in ' ' . to the plunger in a fully extended position.
Figure 27 is a ~.,~ iv~ view showing the device positioning a d~fu.~ ' ' intraocular lens within the eye.
Figure 28 is a cross-sectionai view of an eye showing the positioning of the d~'ul ' '~ intraocular lens into position in the eye by the surgical device.Figure 29 is a cross-sectionai view of an eye showing the positioning of the ~ intraocular lens into a different position in the eye by the surgicai device.
~VO 95122287 PCTIUS95/021127 2 1 8 3 ~ 6 ~
Figure 30 is a side elevational view of an altemative ~,~1;,...... 1 of the lens holding ~I.i~6_ provided with a bevded tip.
Figure 31 is a rear end elevational view of another altemative of the lens holding l-;d6_ provided with grooves in the ~t_~a~ to 5 facilitate folding the cartridge in an open position.
Figure 32 i5 a rear end devational view of another altemative ~ ' of the lens holding lI;~b- provided with grooves in the ~". 6-~ to facilitate folding the cartridge in a closed position.
Figure 33A is a front end devational view of the nozzle of an altemative 10 ~ L " of the lens holding u~ll;u6_.
Figure 33B is a front end elevational view of the nozzle of a further altemative ~ ~- " of the lens holding ...;~ id~, .
DESCRlPrlON OF PREFERRED EMBDODIMENTS
The present invention is directed to a system including methods and devices for ,' of ,~' ' '- intraocular lens structures for surgical placement in the eye.
An inventive device according to the present invention comprises a holder havine a receiver, a lens holder that can be removably inserted into the receiver of the holder, and means such as a moveable plunger disposed within the holder 20 to force and manipulate the lens from the lens holder into the eye.
Preferably, the lens holder is defined by a lens holding 1..;~,. ~ ll ;dL_ for receiving the lens structure. Further, the Ill;~lu~allli~g_ is preferably a structure configured to be opened and closed. The preferred ~,.,l,r' ' of the ...I.,,u~uLlidL~_ receives a lens having prescribed memory ~,;lala~tu~ when in the open position, and performs the function of folding or deforming the lensstructure into a condensed c~ ;,.,. when being closed. Al ~ly, the IlI;~,lU~lllidg~ can be a structure having a ~a~t- -.r defined by a continuous ~ WL~ 9~/22287 PCTIIIS9r~0~0~7 2 1 ~3~6~
, , ~ ~. .
wailed annulus, and a lens could be inserted into the ~la~_.D~ from the e.l4 ~f '~ by . , 1,, rolling, folding, or . ' of these techniques prior to inscrtion into the l..h,l~LI;~,~.
Once a lens is positioned into the ..l;~ _, the ~ is positioned into a plunger device. rrhe assembled device maintains the lens in its condensed S~, during insertion into the eye yet pemlits the deformed lens to retum to its original 5" size and fixed focal length once implanted in t'l~ eye, thercby providing a safe, ev.... t, and surgical proce~ure.
A preferred ' ' of a ~' ~ " intraocular lens ,' device 10 according to the present invention is shown in Figures 1, 2 and 3. The.' device comprises a l...~l~LI;dg~ 12 disposed within a holder 13 ~ a holder body 14 with a receiver 15, and a moveable plunger 16. In Figure 1, the receiver 15 is defined by an opening 17 through the wall of the holder body 14 of thc size and shape shown in Figures 1 and 2. The opening 17 is defined by paraUel edges 17a, 17a, which are rr~ spaced apart to aUow the ~ I~L~ , 12 to be loaded into the receiver 15 of the holder 13, tapered edges 17b, clamping edges 17c, and stop edge 17d. In Figurc I, the 'g 12 is positioned in the receiver 15 between the clamping edges 17c with the plunger e~tending ti~ ~gh the ~ 6~ 12 in a i~osition~ for example, after a lens , ' ~. . procedure.
In Figure 2, the lens holding I ~t.;~it,_ 12 is shown removed from the holder 13 with the plunger 16 in a retracted position for ailowing the o~L,i~6~ 12 containing a loaded lens and its haptic to be inserted within the holder 13. In Figure 3, the holder 13 is shown with the piunger 16 in the extended position without the ~ l;dg~ 12 for purposes of illustration of the WO ~S/222~7 PCT/11~95/02027 2 ~ ~3~62 The plunger 16 is fitted with a threaded end cap 18 at one end, and fitted with a tip 20 at an opposite end. The threaded end cap 18 is provided with a plurality of grooves 22 to a allow a person to tightly grip the cap 18 with his or her finger tips. The threaded end cap 18 is received within a threaded sleeve 245 of the insert holder 14. The threaded end cap 18 can be a separate component attached to the insert holder 13, or integral therewith, as shown in the ...IUI,liUll is Figure 5.
The plunger 16 is installed within the holder 13 in a manner to allow the plunger to be ~ ' therein. In the illustrated . L ' t, the plunger 16 is supported for sliding movement within the holder 13 by guide 26, as shown in Figures S and 6. The outer dimension of the guide 26 is ~tJlJ~ , the same size as the inner ~" of the holder 13 to allow the guide to be inserted within the insert holder. During ~ ., the guide 26 is inserted within the holder 13, and locked into position by pin 28 inserted into a predrilled hole in both thc wall of the holder 13 and guide 26.
The ~,~ ~tiu.~l shape of the plunger 16 as well as the shape of the inner surface of the guide 26 are ~ , a half-circle, as shown in Figure 6. This r -~e~ prevents the plunger 16 from rotating within the holder 13 to maintain the orientation of the tip 20 relative to the holder 13 during operation.
The threade~ end cap 18 is connected to the plunger 16 in a manner to allow the threaded end cap 18 to be rotated relative to the plunger 16. For example, the left end of the plunger 16 (Figure S) is provided with a threaded extension 30, which is secured to the threaded end cap 18 by a nut 32.
Specifically7 the threaded end cap 18 is ~ ' with e~tternal threads 34 and a I ~ ' ' center bore 36 that ends on the right side of the threaded end cap 18 leaving a wall 38.
~ WO g~l22287 I'CT/USg~102027 2 i ~3462 .. . . ..
, . .. i~ . ~ ~
The wall 38 is provided with a hole slightly larger than the outer diameter of the threaded extension 34 to allow the threaded end Cdp 18 to freely rotate on the plunger 16 while being secured to the end of the plunger 16. During cu..;.l.,,~,Lu.., the nut 32 is inserted through the oenter bore 36 and threaded onto th~ extension 30 to secure the threaded end Cdp 18 to the plunger 16. A curYed cap 40 is press fitted into the end of the oenter bore 36 to seal the center bore 36 ~o prevent debris from entering therein during use.
The details of the tip _ are shown in Figures 7 to 12. The p!unger 16 is r ~ with an extension 42 supporting tip 20. The tip 20 structure provides medns for inserting the d.,fu. ~I.dbl~ intraocular lens into the eye dnd , ' the lens within the eye after the insertion step. For example, the tip 20 is faceted in the manner shown in the figures. Specifically, the leftside of the tip 20 shown in Figure 8 is provided with a flat surface facet 42, conical surface 44, and cylindrical surface 46. The right side shown in Figure 11 is provided with a concave surface facet 50.
The end faoe of the tip 20 is designed to push the lens into position onoe i~serted into the eye. For ~xample, the end face is defined by a concave cylindrical surface 52 shown in Figure 8.
Suitable d.fvl ' - intraocular lens for use in the present invention are shown in Figures 13 - 15. The J~,fu ~ll~l_ intraocular lens 54 shown in Figures 13 and 15 includes a lens body 56 with attachment means defined by a pair of haptics 58 each haYing one end anchored in the lens portion 56 and a free end for altachment to the eye tissue. The d.f~ ' intraocular lens 60 shown in Figure 14 includes a lens body 62 and attachment medns defined by a pair of lateral lobes 64 of the lens portion 62.
The details of the preferred lens holding ~ .u~ id~,_ 12 are shown in Figures 16 - 20. The Illi~,lUWilid~j_ 12 comprises a split tubular member 66 extending to a continuous tubular member 67 and an .- nozzle 68.
WO 9~/22287 PCTl~lSgS/~2~27 ` `i ~ t ~i - ` 21 ~3 When the ~ ~altli-lb_ is in a closed position, a continuous circular or oval a~ a,~ of the same diameter extends through the split tubular member 66 through the continuous tubular member 67 and through the , ' nozzle 68. The ~Lfid~ is preferably made of injection molded plastic such as ~I~Iu~jlw.~ The split tubular member 66 is defined by a fixed portion 70 and a moveable portion 72. The fixed portion 70 is fixed relative to the I; ' nozzle 68, and is defined by a tubular portion 74 and extension 72.
The moveable pordon 72 is moveable relative to the fixed portion 70 for operung and closing the split tubular member 66. The moveable portion 72 is defined by a tubular portion 78 and extension 80. A hinge 82 is provided between the fixed portion 70 and moveable portion 72. The hinge 82 is defined by reducing the thickness of the walls of the tubular portion 74 and 75 at the hinge 82, as shown in Figures 17, 18 and Ig. The hinge 82 runs the length of the split tubular member 66 to allow the extension 76 and 78 to be split apart, or brought together to open and close, ~ cly, the split tubular member 66.
The tubular portion 78 of the moveable portion 72 is provided with a sealing edge 84, which is exposed when the lens holding l~ idb_ 12 is opened, as shown in Figure 16A, and seals with a similar sealing edge 86 (See Figures 17 and 21) of the continuous tubular member 67 when the lens holding ~idg_ is closed.
The end of the tip 20 is provided with three (3) equally spaced slots 87a, 87b and 87c of different length provided about the i: ~ thereof, as shown in Figures 20A and 20B. The slot 87a positioned at the top of the tip 20 is the shortest, slot 87c on the right side of the tip 20 is the longest, and slot 87b on the leh side is of medium length. The slots 87a, 87b, 87c cause the lens 54 to rotate as it exits the tip 20.
Other ' " of the ~ l~LIidg~ 12 according to the present invention are shown in Figures 30-33.
~ WO 9'5,'222~7 PCT~IJS'~102(~27 2~ 83~2 The ~I.i~Lc shown in Figure 30 is provided with a beveled tip 94 to facilitate entry of the tip through the incision in the eye during . ' The beveled tip 94 can be set at dl.r ' ' ~ forty-five (45) degrees relative to the I _ _~ through the . i~, 12.
The ~ ' " of the i ' 'g shown in Figures 31 and 32 is provided v~ith a set of grooves 96 provided insido the t~6'- "~ t' The groovos ~ thc edges of the lens being loaded into the 'g to facilitate bending of the lens. s~ir.~ll~, thc edges of the lens a~o placed in the grooves 96 to prevent relative slippage of the edges with the 10 inner surface of the ~,~"~~ through the u~L.;d~_ vhen the i~ is b~ing folded i~ ~ ~ the closed position.
The " of the, u~Llid~,~ shov.~n in Figures 33A and 33B
each have a nozzle 68' having an oval cross-section vith slots 87' differen'dy position as sho vn, ~ , again to facilitate entry through an incision in the 15 eye. Al~l.d~ , the ~IUo~ ~Lùcan bo two half circlos sot apa t and connected tûgether rather tlwl ûval.
The various featuros of the ` 'g shown in Figures 16-21 and 30-33 can be usod in various ' ' to achieved an optimum design for a particular ~r~ n However, all of these features are typically considered , ~ of the basic;
The , of the device 10, except for the L~ 12, are preferably fabricatod from ~dl,l~ material such as stainloss steel or from a disposable rigid plastic such as medical grade ABS or the like.
wo 95~22287 PCT~US~/02027 / ` 21 ~3~2 MEI HODS OF IMPLANTATION
The surgical procedure begins by coating the lens with a surgically compatible lubricant, and loading the lens into the l 'g For e%ample, as shown in Figure 21, a lens 54 having a lens body 56, a leading haptic 58a is 5 load into the ~g 12 while a trailing haptic 58b remains trailing outside the I ~tl;dL_ in the manner shown. s,~;r~l~, the lens 54 is loaded ' .. . 1~ into the opened, 'g 12 until it sits on the inner surfaces of the tubular portions 74 and 78, for e%ample, with a pair of twee2ers. The outer r ' ~ surface of the lens 54 are held by edges 88 and 90 of the tubular portions 74 and 78, ~ . The rear edge of the lens 54 is placed -rr- ~ at the rear edge of the ~ 12. The lens 54 is furlher . ' ' to situate the haptics 58a and 58b in the manner shown. Specifically, haptic S4a is positioned in a leading position and the other haptic 54b is pos;tioned in a trailing position outside with respect to the direction of , ' as indicated by the arrow.
S , '~" the split tubular member 66 of the 1.;~,_ 12 is closed about the lens 54 by forcing the extensions 76 and 80 together with his or her finger tips. The inner surfaces of the tubular portions ~4 and 78 bend and fold the lens S4 when the e%tensions 76 and 80 are forced together, as shown in 20 Figures 22 and 23. Due to the resilient nature of the d~fu. ' intraocular lens 54, the lens 54 conform to the curved inner surface of the tubular portions 74 and 78 without damage thereto, as shown in Figure 23.
The Ilidb~ 12 containing the loaded lens 54 is inserted between the edges 17a, 17a of the opening 17 into the receiver 15 of the holder 13. As the .. ;.,.u~ L.id~,_ 12 is moved forward, the extensions 76 and 80 move past the tapered edges 17b and come to a stop position between the clarnping edges 17c Wo 95122287 PCTIIIS95~(12~1'7 i~ i; ` 2 1 ~ 2 when front portions of the extensions 76 and 80 contact with the stop edge 17d.
The damping edges 17c prevent rotation of the JWL.i~ inside the holder 13.
The user pushes the threaded end cap 18 forward while securing the holder body 14 from movement, forcing the plunger 16 forward within the holda. As the plunger 16 is moved forward, the tip 20 enters into the rear of the L~id~ 12 and misses the trailing haptic 58B until the tip makes contact wit~ ~he loaded lerls 54, as s~ wn in Figure 24. As the plunger 16 is moved forward in this manner, the lens 54 previously lubricated, is forced into the ~ nozzle 68 of the ~ b~ , as shown in Figure 25.
Once the lens 54 enters the . ' llozzle 68, thc threads of the end cap 18 contact with the threads of the sleeve 24 stopping further movement of the plunger 14 forward in this manner. The end cap 18 is slightly rotated to engage the threads of the end cap 18 with the threads of the sleeve 24. At this point, the surgical device is ready for the , ' step. The nozzle is insert through the incision in the eye, and the end cap 18 is rotated tD con~ e the forwari movement of the plunger 16 by continued rotation of the end cap 18 relative to the holder body 14 to expei the lens from the nozzle into the interior of the eye, as shown in Figure 26. This manner of screw a.l~ for moving the plunger 16 forward provides for precise control and accuracy conceming forcing the lens 54 through the remaining por~ion of the tip 68 into the eye during the . ' procedure. The deformed lens after exiting the nozzle 16 retums to its original ~ full size and fixed foeal length.
After the lens is inser~ed into the eye, the end cap 18 is further rotated to fully expose the tip 20 O~ e plunger 16, as shown in Figures 28 and 29, to allowthe lens to be pushed forward, side . ' ' to rotate the lens, and pushed down to properly position the lens within the eye without the aid of other surgicai ~rO '351222X7 PCT~1~9~/02027 o 21 ~3~62 The ~ '1, of the tip 20 is important du~ing the i~
process. The faceted tip 20 provides a clearanoe between the tip 20 and the inner surface of the ~ through the ~ ,_ 12 to a ' the trailing haptic 58b during movemenl of the lens within the ~uI.iJ~,_ 12, as 5 shown in Figures 25 and 26. Sp~ifi~l~, there exists a sufficient clearance between the ilat surface facet 44 and the inner wall of the I _ . _~ through the l-;J6- 12. During the , proress, the trailing haptic floats around in the space bctween the extension 42 of the tip 20 and the inner wall ofthe ~, ~6~ ..J, as shown in Figure 25. This prevents any chanoe of damage to 10 the trailing haptic, for example, by being caught between the tip 20 and the lens 54 during the .' process. The leading haptic moves through the ~"_~,.~ unimpeded du~ing the ,' prooess preventing any damage thereto.
Another ~ ' ' of the present invention is shown in Figs. 34-38.
The lens ~& 100 comprises a lens holding portion 102 and a nozzle portion 104. The lens 'g 100 is shown installed in a fi~ture 106 (e.g. end of . ' device 10) in Figs. 34, 35 and 36. The fixture 106 is basically a cylinder with a slot 108 having tapered edges 110 for guiding the lens l.i~,_ 100 into the fixtule 106.
The lens holding portion 102 is defined by a split tubular Cu.. ~u.,liO.~
including a fixed tubular portion 112 and a moveable tubular portion 114. The fixed tubular portion 112 is provided with an extension 116 and the moveable tubular portion 114 is provided with an extension 118.
The important features of this ' - ' include alignment means for aligning the extensions 116 and 118 when the lens ~u~ ,_ is closed, and means for tightly holding the lens l..h,lu~ul-iJgC 100 closed when inserted in the fixture 106.
~ WO 95122:~87 PCI lUSg~102027 2 1 ~3~6~
.
An example of means for aligning the extensions 116 and 118 when the lens ,~.uwi ~b 100 is closed is an alignment groove ~20 ~ with an align ~_nt nib 122, as shown in Fig. 37. The alignment grcove 120 and alignment nib 122 extending the length of the extensions 116 and 118, 5 .~L~ . However, it is not necessary the the alignment groove 120 and alignment nib 122 run the entire length of the extensions 116 and 118, and can still be effective is provided only for a porfion of the length of tbe ext~nsions.
Further, the alignment grooYe 120 and alignment nib læ can be aligned with other extension alignment means such as ' " ' alignment tabs, 10 }"u~ surfaces, etc. ~ ' ~ the alignment of the extensions 116 and 118 when the len v~L~ is closed is important for " the alignment of the moveable tubular porfion 114 relative to the fixed tubular portion 112. This ~lignment of the tubular pofions maintains the inner seams of the e~tensions 116 and 118 inside the ~ 124 in alignment preventing IS exposcd edges of these seams that can cause damage to the ' ~ ' ' intraocularlens during loading and/or insefion operations, 1 ' 1~ during the transition of the ' ~ '~ intraocular lens from the lens holding porfion into the nozzle porfion during the inserfion operation.
Means means for tightly holding the lens uwLIidb_ 100 closed when 20 inserted in the ff~ture 106 can be provided by a varitey of structural features of both the fixture 106 and/or lens I.i~b_ 100.
Due to the slot 108 c.. ~fi". ~ ..A of the fixture 106, means for wedging the extensions 116 and 118 togaher provides an il~.A~I~ , and effective manner of achieving the desired function.
Forexample, theextensions 116and 118canbeprovidedwithl/.u~ ;o,ls 126 and 128, l~ . l.r, that cooperated with the edges of the slot 108 of the fLxture 106, as shown in Fig. 38. The IJlU~ 126 and 128 serve as means for wedging the extensions 126 and 128 tightly between the edga of the slot 10 -WO 95/222X7 PCTII1S~IO2027 i. ., ; ' .J
2 1 ~34 6~
ensuring that the lens ~ id6~ is tightly held closed during the insertion operation. Further, the ~,.uL,. again provide means for also aligning the extensions 116 and 118 providing the benefit described above with respect to alignment of the extension 126 and 128 to prevent damage to the intraocular lens.
S The 1~ 126 and 128 resiliently, and possibly plastically deform to some extent during wedging utilizing the resilient properties of the plastic material of the lens 'g 100 to hold the lens holding portion 102 tightly closed and the extensions 116 and 118 acculately aligned.
The ~ JLL ' 126 and 128 can be in the form of strips, dots, squares or other shaped ~ o;~ extending from the surfaces of the the extensions 116 and 118.
RELATED APPLICATION(S) TtTis application is a in part application of U.S. patent aMlication SeriaTT No. 07/953,251 filed on September 30, 1992, now ` ' ~ ' F[ELD OF TIIE INVEN~ON
This invention relates to an improved l.l;.,lT~Lfi~b_ for use with devices for the surgical ~ , ' of d.F~,TI ' ' intraocular lenses into the eye.
I~ACKGROUND OF THE INVENTION
Intraocular lenses have gained wide acceptance in l . '. of human crystaTline lenses after a variety of cataract removal procedures. The human crystalline lens is generalTly recognized to be a i . structure having a thickness of about five (5) --i11;-- t--` and a diameter of about nine (9) '-T' ' The lens is suspended behind the irTs by zonula fibers which connect ~VO 95122287 PC~T~U59SI~)21127 2 1 ~3462 the lens to the ciliary body. A lens capsule surrounds the lens, the front portion of the capsule being commonly known as the anterior capsule and the back portion commonly known as the posterior capsule.
Numerous procedures for the removal of cataracts have been developed 5 in which the lens is removed from the eye and replaced by an artificial lens implant. The extraction procedure may generally be ~ ~ ' as;
(in which the lens is removed together with the lens capsule) and ~ l r- 'U~
(in which the anterior capsule is removed with the lens, and the posterior capsule is left intact).
Since Ridley implanted the first artificial lens in about 1949, the problems associated with cataract extraction and lens ' have received a great deal of attention from ~rl ' ' - surgeons. Various types of artificial lenses have been proposed, and a~ ul surgical procedures have been developed which strive to reduce patient discomfort and to reduce p~ u~.dL;~
s ~-~r Reference is made in this connection to ~ ~ r ' I by N. Jaffe et al.; 'History of Intraocular Implants~ by D.P. Choyce (Annals of C~' ' ' ' ,~, October lg73); U.S. Patent No. 4,251,887 issued to Anis on February 24, 1981; U.S. Patent No. 4,092,743 issued to Kelman on November 8, 1977; ~rc~n~r~iCOn of Flexible Posterior Chamber Implants", presented at the American Intraocular Implant Society Symposium April 23, 1982, by Charles Berkert, M.D.; and "the Simcoe Posterior Lens~ (Cilco, Inc. 1980); U.S. Patent No. 4,573,998 issued to Mazzocco on March 4, 1986, and U.S. patent application Ser. No. 400,605 for "Improved Fixation System for Intraocular Lens Structures", filed July 22, 1982, U.S. Patent No. 4,702,244 issued to Mazzocco on October 27, 1987; and U.S. Patent No. 4,715,373 issued to Mazzocco et al.
on December 29, 1987, which disclosures are hereby i.~ ,. ' by reference.
-'O 9~';/222~7 P~:T~ITS~5/(12(~7 . r~ 21~3~46.?
Of particular interest in the context of the present invention is the d.,~.~ of surgical techniques requiring relatively small incisions in the ocular tissue for the removal of cataracts as disclosed in U.S. Patent No.
4,002,16g and U.S. Patent No. 3,996,935. A number of skilled artisans have disclosed intraocular lens structures . , ~, an optical wne portion generally made of rigid materials such as glass or plastics suitable for optical uæ.
However, one of the principal d;~i~_ - of the ~ .. ' rigid intraocular lens is that .' of the lens requires large incisions in the ocular tissue. This type of surgical procedure leads to a relatively high 10 l . ' - rate, among other disadvantages. For instance, the serious dangers asseciated with .' of a rigid lens structure include increased risk of infection, retinal ~ r ..~, and laceration of the oeular tissue, ~ i.,ul.ulr with respect to the pupil.
~1 ." 1, '~, those skilled in the art have re~ognized a significant need for surgical tools for .' of d~ intraocular lens struetures whieh afford the eliniea~ advantag of using relatively small incision teehniqu, whieh previde a safer and more convenient surgical procedure. In partieular, those skilled in the art of ~I~ f, " ", .1,1. intraocular lenses and methods and devices for . ' have also recognized a signifieant need for surgical tools whieh do not require widening of the wound made in the ocular tissue during or after , ' but will deform the intraocular lens to a ~ t~ - ' cross section in a strased state and which allow the ~r~ '' I ' surgeon to inspeet the lens prior to ,' without l , ' in the eye. The present invention T~ulfills these needs.
The present invention was derived by improving the methods and devices in the above-identifled patents, specifically the methods of U.S. Patent No.
4,573,998 and the devices of U.S. Patent No. 4,702,244.
WO 95/222X / pCrll 1~951~2027 ~ . ! 2 1 ~ 3 ~
SUMMARY OF TISE INVENTION
An object of the present invention is to provide an improved ~LliJl!~_ for use with devices for surgical r~ ' " of J~'u. ''-intraocular lenses.
Another object of the present invention is to provide an improved lens ~tlirigv comprising a lens holding portion and nozzle having a through bore with a pair of opposed grcovesa lens holding portion in covice including a lens holder, which can be loaded with a d~ful ' ' intraocular lens, and then inserted into a holder having means for implanting the lens.
A further object of the present invention is to provide a surgical device including a lens holder define by a ~ lid~_ comprising a lens holding portion in ~ ' with a nozzie for implanting the lens.
A still further object of the present invention is to provide a lens holding ~ L,i i~,_ for receiving a lens comprising a split tubular member having a 15 fixed porlion with an extension, and a moveable portion with an extension foropnung and closing the ~llidg_, which extensions prevent rotation between the I u~I.i~it,_ and holder when installed in the holder.
An even further object of the present invention is to provide a lens holding 1..;_1~1l;~_ having a noz~ie provided with slots for rotating the lens as it exits the noz~ie.
An object of the present invention is to provide a surgical device including a lens holder and a holder for the lens holder, the holder comprising a receiverfor the lens holder and a plunger for inserting the lens.
Another object of the present invention is to provide a holder defined by a cylindricai tubular member with an opening through the wail of the tubular member defining a receiver for the lens holder, and a piunger having a tip for contacting with and moving a lens contained in the lens holder.
WO ~CJ22287 PCT1115~5~02(12 ~
2 1 ~3~ 62 ~ . ~ . i "
s A further object of the present invention is to provide a plunger with a faceted tip that provides clearance for a trailing haptic in a ~ r through thc lens holder during the . ' process to prevent damage to the trailing haptic.
An even further object of the present invention is to provide a plunger having a tip with a concave conicai surface at the tip thereof for grabbing the lens during the .' process.
An object of the present invention is to provide improved methods of implanting d~fu. ' ' intraocuiar lenses;
Another object of the present invention is to provide a method including loading a ~ in~-t~ cular lens into a lens holder having an . ' nozzie, L ' ,, the intraocular lens within the lens holder, and implanting the lens into the eye.
The present invention concerns a system including methods and devices 15 for . ' of intraocular lenses into the eye.
The surgicai device according to the present invention includes the ' of a lens holder and a holder for the lens holder. The preferred lens holder comprises the ' of a lens receiYer and an . ' nozzle.
The lens receiver is preferably defined by a ..;~.uwL-;~i~ comprising a split 20 tubular member having a fixed tubular portion with an extension connected to a moveable tubular portion with an extension at a hinge. This ~nnf g ' ailows the ~l~;Jb- to be opened to accept a ~iLfu~ bl., intraocular lens, and closed to condense the lens into the p~ . The split tubular portion is connected to a nozzle with a continuous ~ ~6-~ passing through the tubular 25 member and the nozzle.
~'(~ 95~222X7 PCTII.IS951~2U27 The lens holder is inserted into a holder having means for driving or 'A ~ " ,, the lens from the lens holder into the eye. In the preferred t, the holder is proYided with a plunger for driving the lens from the lens holder into the eye. Purther, the holder is configured to receive a S ~ui ig having a nozzle.
The preferred holder includes means to prevent the ~uLlidg_ from rotating witbin the holder, and means for preventing the plungN from rotating within the holder. The means for preventing rotation of the IIU~ within the holder can be define by providing the . .~ lg. with one or more extensions that cooperate with the opening of the receiver of the holder to prevent rotation. The means for preventing the plunger from rotating within the holder can be defined by providing the plunger and a sleeve within the holder with a particular cross ' shape that prevents rotation, for example, a half-circle shape.
The preferred holder includes a plunger with a threaded cap with a threaded sleeve of the holder body for dialing the plunger forward withinthe holder for precise and accurate movement of the lens during the , ' process. The holder is configured so that the plunger can be moved a IJla~ ' ' ' distance by sliding motion within the holder body followed by ~ of the threaded cap of the plunger with the threaded sleeve of the holder body to continue the forward progress of the plunger tip.
The preferred plunger tip is defined by a faceted tip having various surfaces for moving and . ' ~ the lens from the lens holder and within the eye. The tip is designed to provide a clearance between the tip and the inner surface of the ~_wa,~ through lens holder to ~ ' the trailing haptic and prevent damage thereto. Once the lens is inserted into the eye, the tip can be used to push and rotated the lens into proper position within the eye.
~ WO !~5122287 PCTll~ 5/02(~2~
21 ~3462 A method according to the present invention includes lubricating the surface of a d~fw,....blc intraocular lens with a surgically compatible lubricant, and loading the lens into a ~ I~Llid~c in the opened position. The owl.iJg_ is closed while ~ ' _ the lens by a folding action into a S shape so that it can be forced through the p~ in the ~" The uwl-iJb_ is inserted into the holder with the plunger retracted.
The plunger is moved forward in a sliding manner by pushing the plunger forward while holding the hold body still, This action forces the lens from thetubular member portion of the ~ iJg_ into the nozzle portion. At this 10 point the threads of the threaded end cap of the plunger engage with the threads of the threaded sleeve. The threaded end cap i5 rotate slightly to engage the threads. The device is now ready for the ,' process.
The nozzle of the ...~ ,iJb_ is placed through a small incision in the eye. The threaded end cap of the plunger is rotated or dialed to further advanceIS the lens forward through the nozzle and into the cye. The threaded end cap isfurther dialed to e~pos~d the tip of the plunger within the eye and push the lens into position. The tip can be used to also rotate the lens within the eye for positioning of the haptics.
BRlEF DESCRIPIION OF THE DRAWINGS
Figure I is a ~.~Li~'~, view of one ~ ~ of device according to the prescnt invention with a lens holding ...;_ ~h~ridgG positioned in the device for . of <1 f~ lr lens structures for placement in the eye.
Figure 2 is a pe. .~liv~ view of the surgical device depicted in Figure I
with the plunger retracted, and with the lens holding, ~I-;dg~ removed.
Figure 3 is a side view of the device depicted in Figure 2, with the plunger in the e~dended position.
WC) 9~122287 PCT111595102027 o ;/i.`.j.~. ;~ 2i~3~62 Figure 4 is a side elevationai view of the device shown in Figure 1.
Figure S is a detailed ~.~r G,i~ cross-sectionai view of the device shown in Figure 4.
Figure 6 is a dehiled transverse cross-sectionai view of the device, as S indicated in Figure 5.
Figure 7 is a det~iled end view of the device, as indicated in Figure 5.
Figure 8 is an enlarged dehiled left side elevational view of the tip of the plunger in the spaciai orienhtion as shown in Figure 1.
Figure 9 is an eniarged det~iled end view of the tip shown in Figure 8.
Figure 10 is an enlarged dehiled top planar view of the tip of the plunger.
Figure 11 is an enlarged dehile~i right side elevationai view of the tip of the plunger in the spacial n~ q~illn, as shown in Figure 4.
Figure 12 is an eniarged dehiled bottom view of the tip of the plunger in the spacial ~ , as shown in Figure 1.
Figure 13 is a ~,~ view of a lens for use in the present invention.
Figurc 14 is a ~l~t~t;~, view of another type of lens for use in the present invention.
Figure 15 is a side view of the lens shown in Figure 13.
Figure 16 is a ~.~Li~ view of the lens holding ~ ~L~ ,_ in the 20open position to allow a lens to be loaded therein.
Figure 16A is another perspective view of the lens holding L~ C
in the open position.
Figure 17 is a rear end elevationai view of the lens holding ~Llhl~
in the open position.
Figure l8 is a front end elevational view of the lens holding ,,,;~I~L i~L_ in the open position.
Figure 19 is a rear end elevationai view of the lens holding l..._lU~ Ll id~,_ in the closed position.
~ W~ 9~1222#7 PCT/11595~(~2l)27 2 1 S 3 '~
Figure 20 is a front end elevationai view of the lens holding ".~.~I.id~,_ in the closed pOSitiOn.
Figure 20A is a detailed end view of the nozzle showing three (3) slots of different length equaily spaced about the e;., r _ of the tip.
Figure 20B is a det~iled pc.~iv~; view of the tip showing the three (3) slots of different length.
Figure 20C is a detailed side view showing the beveled tip.
Figure 2~ is a top planar view of the lens hoiding l.; '~_ in the oi~en position.
10Figure 22 is a side elevationai view of the lens holding ~ g_ in the closed i)osition.
Figure 23 is a rear end elevationai view of the lens holding u~LI;db~
in the closed position.
Figure 24 is a broicen away side view of the device showing the lens 15 holding ~ b- in ' ' . to the plunger in the retracted position.
Figure 25 is a broken away side view of the device showing the lens holding I-;~i~ in r~ . to the plunger in a partiaily extended position.
Figure 26 is a broken away side view of the device showing the lens 20 holding ' ~I-; ig_ in ' ' . to the plunger in a fully extended position.
Figure 27 is a ~.,~ iv~ view showing the device positioning a d~fu.~ ' ' intraocular lens within the eye.
Figure 28 is a cross-sectionai view of an eye showing the positioning of the d~'ul ' '~ intraocular lens into position in the eye by the surgical device.Figure 29 is a cross-sectionai view of an eye showing the positioning of the ~ intraocular lens into a different position in the eye by the surgicai device.
~VO 95122287 PCTIUS95/021127 2 1 8 3 ~ 6 ~
Figure 30 is a side elevational view of an altemative ~,~1;,...... 1 of the lens holding ~I.i~6_ provided with a bevded tip.
Figure 31 is a rear end elevational view of another altemative of the lens holding l-;d6_ provided with grooves in the ~t_~a~ to 5 facilitate folding the cartridge in an open position.
Figure 32 i5 a rear end devational view of another altemative ~ ' of the lens holding lI;~b- provided with grooves in the ~". 6-~ to facilitate folding the cartridge in a closed position.
Figure 33A is a front end devational view of the nozzle of an altemative 10 ~ L " of the lens holding u~ll;u6_.
Figure 33B is a front end elevational view of the nozzle of a further altemative ~ ~- " of the lens holding ...;~ id~, .
DESCRlPrlON OF PREFERRED EMBDODIMENTS
The present invention is directed to a system including methods and devices for ,' of ,~' ' '- intraocular lens structures for surgical placement in the eye.
An inventive device according to the present invention comprises a holder havine a receiver, a lens holder that can be removably inserted into the receiver of the holder, and means such as a moveable plunger disposed within the holder 20 to force and manipulate the lens from the lens holder into the eye.
Preferably, the lens holder is defined by a lens holding 1..;~,. ~ ll ;dL_ for receiving the lens structure. Further, the Ill;~lu~allli~g_ is preferably a structure configured to be opened and closed. The preferred ~,.,l,r' ' of the ...I.,,u~uLlidL~_ receives a lens having prescribed memory ~,;lala~tu~ when in the open position, and performs the function of folding or deforming the lensstructure into a condensed c~ ;,.,. when being closed. Al ~ly, the IlI;~,lU~lllidg~ can be a structure having a ~a~t- -.r defined by a continuous ~ WL~ 9~/22287 PCTIIIS9r~0~0~7 2 1 ~3~6~
, , ~ ~. .
wailed annulus, and a lens could be inserted into the ~la~_.D~ from the e.l4 ~f '~ by . , 1,, rolling, folding, or . ' of these techniques prior to inscrtion into the l..h,l~LI;~,~.
Once a lens is positioned into the ..l;~ _, the ~ is positioned into a plunger device. rrhe assembled device maintains the lens in its condensed S~, during insertion into the eye yet pemlits the deformed lens to retum to its original 5" size and fixed focal length once implanted in t'l~ eye, thercby providing a safe, ev.... t, and surgical proce~ure.
A preferred ' ' of a ~' ~ " intraocular lens ,' device 10 according to the present invention is shown in Figures 1, 2 and 3. The.' device comprises a l...~l~LI;dg~ 12 disposed within a holder 13 ~ a holder body 14 with a receiver 15, and a moveable plunger 16. In Figure 1, the receiver 15 is defined by an opening 17 through the wall of the holder body 14 of thc size and shape shown in Figures 1 and 2. The opening 17 is defined by paraUel edges 17a, 17a, which are rr~ spaced apart to aUow the ~ I~L~ , 12 to be loaded into the receiver 15 of the holder 13, tapered edges 17b, clamping edges 17c, and stop edge 17d. In Figurc I, the 'g 12 is positioned in the receiver 15 between the clamping edges 17c with the plunger e~tending ti~ ~gh the ~ 6~ 12 in a i~osition~ for example, after a lens , ' ~. . procedure.
In Figure 2, the lens holding I ~t.;~it,_ 12 is shown removed from the holder 13 with the plunger 16 in a retracted position for ailowing the o~L,i~6~ 12 containing a loaded lens and its haptic to be inserted within the holder 13. In Figure 3, the holder 13 is shown with the piunger 16 in the extended position without the ~ l;dg~ 12 for purposes of illustration of the WO ~S/222~7 PCT/11~95/02027 2 ~ ~3~62 The plunger 16 is fitted with a threaded end cap 18 at one end, and fitted with a tip 20 at an opposite end. The threaded end cap 18 is provided with a plurality of grooves 22 to a allow a person to tightly grip the cap 18 with his or her finger tips. The threaded end cap 18 is received within a threaded sleeve 245 of the insert holder 14. The threaded end cap 18 can be a separate component attached to the insert holder 13, or integral therewith, as shown in the ...IUI,liUll is Figure 5.
The plunger 16 is installed within the holder 13 in a manner to allow the plunger to be ~ ' therein. In the illustrated . L ' t, the plunger 16 is supported for sliding movement within the holder 13 by guide 26, as shown in Figures S and 6. The outer dimension of the guide 26 is ~tJlJ~ , the same size as the inner ~" of the holder 13 to allow the guide to be inserted within the insert holder. During ~ ., the guide 26 is inserted within the holder 13, and locked into position by pin 28 inserted into a predrilled hole in both thc wall of the holder 13 and guide 26.
The ~,~ ~tiu.~l shape of the plunger 16 as well as the shape of the inner surface of the guide 26 are ~ , a half-circle, as shown in Figure 6. This r -~e~ prevents the plunger 16 from rotating within the holder 13 to maintain the orientation of the tip 20 relative to the holder 13 during operation.
The threade~ end cap 18 is connected to the plunger 16 in a manner to allow the threaded end cap 18 to be rotated relative to the plunger 16. For example, the left end of the plunger 16 (Figure S) is provided with a threaded extension 30, which is secured to the threaded end cap 18 by a nut 32.
Specifically7 the threaded end cap 18 is ~ ' with e~tternal threads 34 and a I ~ ' ' center bore 36 that ends on the right side of the threaded end cap 18 leaving a wall 38.
~ WO g~l22287 I'CT/USg~102027 2 i ~3462 .. . . ..
, . .. i~ . ~ ~
The wall 38 is provided with a hole slightly larger than the outer diameter of the threaded extension 34 to allow the threaded end Cdp 18 to freely rotate on the plunger 16 while being secured to the end of the plunger 16. During cu..;.l.,,~,Lu.., the nut 32 is inserted through the oenter bore 36 and threaded onto th~ extension 30 to secure the threaded end Cdp 18 to the plunger 16. A curYed cap 40 is press fitted into the end of the oenter bore 36 to seal the center bore 36 ~o prevent debris from entering therein during use.
The details of the tip _ are shown in Figures 7 to 12. The p!unger 16 is r ~ with an extension 42 supporting tip 20. The tip 20 structure provides medns for inserting the d.,fu. ~I.dbl~ intraocular lens into the eye dnd , ' the lens within the eye after the insertion step. For example, the tip 20 is faceted in the manner shown in the figures. Specifically, the leftside of the tip 20 shown in Figure 8 is provided with a flat surface facet 42, conical surface 44, and cylindrical surface 46. The right side shown in Figure 11 is provided with a concave surface facet 50.
The end faoe of the tip 20 is designed to push the lens into position onoe i~serted into the eye. For ~xample, the end face is defined by a concave cylindrical surface 52 shown in Figure 8.
Suitable d.fvl ' - intraocular lens for use in the present invention are shown in Figures 13 - 15. The J~,fu ~ll~l_ intraocular lens 54 shown in Figures 13 and 15 includes a lens body 56 with attachment means defined by a pair of haptics 58 each haYing one end anchored in the lens portion 56 and a free end for altachment to the eye tissue. The d.f~ ' intraocular lens 60 shown in Figure 14 includes a lens body 62 and attachment medns defined by a pair of lateral lobes 64 of the lens portion 62.
The details of the preferred lens holding ~ .u~ id~,_ 12 are shown in Figures 16 - 20. The Illi~,lUWilid~j_ 12 comprises a split tubular member 66 extending to a continuous tubular member 67 and an .- nozzle 68.
WO 9~/22287 PCTl~lSgS/~2~27 ` `i ~ t ~i - ` 21 ~3 When the ~ ~altli-lb_ is in a closed position, a continuous circular or oval a~ a,~ of the same diameter extends through the split tubular member 66 through the continuous tubular member 67 and through the , ' nozzle 68. The ~Lfid~ is preferably made of injection molded plastic such as ~I~Iu~jlw.~ The split tubular member 66 is defined by a fixed portion 70 and a moveable portion 72. The fixed portion 70 is fixed relative to the I; ' nozzle 68, and is defined by a tubular portion 74 and extension 72.
The moveable pordon 72 is moveable relative to the fixed portion 70 for operung and closing the split tubular member 66. The moveable portion 72 is defined by a tubular portion 78 and extension 80. A hinge 82 is provided between the fixed portion 70 and moveable portion 72. The hinge 82 is defined by reducing the thickness of the walls of the tubular portion 74 and 75 at the hinge 82, as shown in Figures 17, 18 and Ig. The hinge 82 runs the length of the split tubular member 66 to allow the extension 76 and 78 to be split apart, or brought together to open and close, ~ cly, the split tubular member 66.
The tubular portion 78 of the moveable portion 72 is provided with a sealing edge 84, which is exposed when the lens holding l~ idb_ 12 is opened, as shown in Figure 16A, and seals with a similar sealing edge 86 (See Figures 17 and 21) of the continuous tubular member 67 when the lens holding ~idg_ is closed.
The end of the tip 20 is provided with three (3) equally spaced slots 87a, 87b and 87c of different length provided about the i: ~ thereof, as shown in Figures 20A and 20B. The slot 87a positioned at the top of the tip 20 is the shortest, slot 87c on the right side of the tip 20 is the longest, and slot 87b on the leh side is of medium length. The slots 87a, 87b, 87c cause the lens 54 to rotate as it exits the tip 20.
Other ' " of the ~ l~LIidg~ 12 according to the present invention are shown in Figures 30-33.
~ WO 9'5,'222~7 PCT~IJS'~102(~27 2~ 83~2 The ~I.i~Lc shown in Figure 30 is provided with a beveled tip 94 to facilitate entry of the tip through the incision in the eye during . ' The beveled tip 94 can be set at dl.r ' ' ~ forty-five (45) degrees relative to the I _ _~ through the . i~, 12.
The ~ ' " of the i ' 'g shown in Figures 31 and 32 is provided v~ith a set of grooves 96 provided insido the t~6'- "~ t' The groovos ~ thc edges of the lens being loaded into the 'g to facilitate bending of the lens. s~ir.~ll~, thc edges of the lens a~o placed in the grooves 96 to prevent relative slippage of the edges with the 10 inner surface of the ~,~"~~ through the u~L.;d~_ vhen the i~ is b~ing folded i~ ~ ~ the closed position.
The " of the, u~Llid~,~ shov.~n in Figures 33A and 33B
each have a nozzle 68' having an oval cross-section vith slots 87' differen'dy position as sho vn, ~ , again to facilitate entry through an incision in the 15 eye. Al~l.d~ , the ~IUo~ ~Lùcan bo two half circlos sot apa t and connected tûgether rather tlwl ûval.
The various featuros of the ` 'g shown in Figures 16-21 and 30-33 can be usod in various ' ' to achieved an optimum design for a particular ~r~ n However, all of these features are typically considered , ~ of the basic;
The , of the device 10, except for the L~ 12, are preferably fabricatod from ~dl,l~ material such as stainloss steel or from a disposable rigid plastic such as medical grade ABS or the like.
wo 95~22287 PCT~US~/02027 / ` 21 ~3~2 MEI HODS OF IMPLANTATION
The surgical procedure begins by coating the lens with a surgically compatible lubricant, and loading the lens into the l 'g For e%ample, as shown in Figure 21, a lens 54 having a lens body 56, a leading haptic 58a is 5 load into the ~g 12 while a trailing haptic 58b remains trailing outside the I ~tl;dL_ in the manner shown. s,~;r~l~, the lens 54 is loaded ' .. . 1~ into the opened, 'g 12 until it sits on the inner surfaces of the tubular portions 74 and 78, for e%ample, with a pair of twee2ers. The outer r ' ~ surface of the lens 54 are held by edges 88 and 90 of the tubular portions 74 and 78, ~ . The rear edge of the lens 54 is placed -rr- ~ at the rear edge of the ~ 12. The lens 54 is furlher . ' ' to situate the haptics 58a and 58b in the manner shown. Specifically, haptic S4a is positioned in a leading position and the other haptic 54b is pos;tioned in a trailing position outside with respect to the direction of , ' as indicated by the arrow.
S , '~" the split tubular member 66 of the 1.;~,_ 12 is closed about the lens 54 by forcing the extensions 76 and 80 together with his or her finger tips. The inner surfaces of the tubular portions ~4 and 78 bend and fold the lens S4 when the e%tensions 76 and 80 are forced together, as shown in 20 Figures 22 and 23. Due to the resilient nature of the d~fu. ' intraocular lens 54, the lens 54 conform to the curved inner surface of the tubular portions 74 and 78 without damage thereto, as shown in Figure 23.
The Ilidb~ 12 containing the loaded lens 54 is inserted between the edges 17a, 17a of the opening 17 into the receiver 15 of the holder 13. As the .. ;.,.u~ L.id~,_ 12 is moved forward, the extensions 76 and 80 move past the tapered edges 17b and come to a stop position between the clarnping edges 17c Wo 95122287 PCTIIIS95~(12~1'7 i~ i; ` 2 1 ~ 2 when front portions of the extensions 76 and 80 contact with the stop edge 17d.
The damping edges 17c prevent rotation of the JWL.i~ inside the holder 13.
The user pushes the threaded end cap 18 forward while securing the holder body 14 from movement, forcing the plunger 16 forward within the holda. As the plunger 16 is moved forward, the tip 20 enters into the rear of the L~id~ 12 and misses the trailing haptic 58B until the tip makes contact wit~ ~he loaded lerls 54, as s~ wn in Figure 24. As the plunger 16 is moved forward in this manner, the lens 54 previously lubricated, is forced into the ~ nozzle 68 of the ~ b~ , as shown in Figure 25.
Once the lens 54 enters the . ' llozzle 68, thc threads of the end cap 18 contact with the threads of the sleeve 24 stopping further movement of the plunger 14 forward in this manner. The end cap 18 is slightly rotated to engage the threads of the end cap 18 with the threads of the sleeve 24. At this point, the surgical device is ready for the , ' step. The nozzle is insert through the incision in the eye, and the end cap 18 is rotated tD con~ e the forwari movement of the plunger 16 by continued rotation of the end cap 18 relative to the holder body 14 to expei the lens from the nozzle into the interior of the eye, as shown in Figure 26. This manner of screw a.l~ for moving the plunger 16 forward provides for precise control and accuracy conceming forcing the lens 54 through the remaining por~ion of the tip 68 into the eye during the . ' procedure. The deformed lens after exiting the nozzle 16 retums to its original ~ full size and fixed foeal length.
After the lens is inser~ed into the eye, the end cap 18 is further rotated to fully expose the tip 20 O~ e plunger 16, as shown in Figures 28 and 29, to allowthe lens to be pushed forward, side . ' ' to rotate the lens, and pushed down to properly position the lens within the eye without the aid of other surgicai ~rO '351222X7 PCT~1~9~/02027 o 21 ~3~62 The ~ '1, of the tip 20 is important du~ing the i~
process. The faceted tip 20 provides a clearanoe between the tip 20 and the inner surface of the ~ through the ~ ,_ 12 to a ' the trailing haptic 58b during movemenl of the lens within the ~uI.iJ~,_ 12, as 5 shown in Figures 25 and 26. Sp~ifi~l~, there exists a sufficient clearance between the ilat surface facet 44 and the inner wall of the I _ . _~ through the l-;J6- 12. During the , proress, the trailing haptic floats around in the space bctween the extension 42 of the tip 20 and the inner wall ofthe ~, ~6~ ..J, as shown in Figure 25. This prevents any chanoe of damage to 10 the trailing haptic, for example, by being caught between the tip 20 and the lens 54 during the .' process. The leading haptic moves through the ~"_~,.~ unimpeded du~ing the ,' prooess preventing any damage thereto.
Another ~ ' ' of the present invention is shown in Figs. 34-38.
The lens ~& 100 comprises a lens holding portion 102 and a nozzle portion 104. The lens 'g 100 is shown installed in a fi~ture 106 (e.g. end of . ' device 10) in Figs. 34, 35 and 36. The fixture 106 is basically a cylinder with a slot 108 having tapered edges 110 for guiding the lens l.i~,_ 100 into the fixtule 106.
The lens holding portion 102 is defined by a split tubular Cu.. ~u.,liO.~
including a fixed tubular portion 112 and a moveable tubular portion 114. The fixed tubular portion 112 is provided with an extension 116 and the moveable tubular portion 114 is provided with an extension 118.
The important features of this ' - ' include alignment means for aligning the extensions 116 and 118 when the lens ~u~ ,_ is closed, and means for tightly holding the lens l..h,lu~ul-iJgC 100 closed when inserted in the fixture 106.
~ WO 95122:~87 PCI lUSg~102027 2 1 ~3~6~
.
An example of means for aligning the extensions 116 and 118 when the lens ,~.uwi ~b 100 is closed is an alignment groove ~20 ~ with an align ~_nt nib 122, as shown in Fig. 37. The alignment grcove 120 and alignment nib 122 extending the length of the extensions 116 and 118, 5 .~L~ . However, it is not necessary the the alignment groove 120 and alignment nib 122 run the entire length of the extensions 116 and 118, and can still be effective is provided only for a porfion of the length of tbe ext~nsions.
Further, the alignment grooYe 120 and alignment nib læ can be aligned with other extension alignment means such as ' " ' alignment tabs, 10 }"u~ surfaces, etc. ~ ' ~ the alignment of the extensions 116 and 118 when the len v~L~ is closed is important for " the alignment of the moveable tubular porfion 114 relative to the fixed tubular portion 112. This ~lignment of the tubular pofions maintains the inner seams of the e~tensions 116 and 118 inside the ~ 124 in alignment preventing IS exposcd edges of these seams that can cause damage to the ' ~ ' ' intraocularlens during loading and/or insefion operations, 1 ' 1~ during the transition of the ' ~ '~ intraocular lens from the lens holding porfion into the nozzle porfion during the inserfion operation.
Means means for tightly holding the lens uwLIidb_ 100 closed when 20 inserted in the ff~ture 106 can be provided by a varitey of structural features of both the fixture 106 and/or lens I.i~b_ 100.
Due to the slot 108 c.. ~fi". ~ ..A of the fixture 106, means for wedging the extensions 116 and 118 togaher provides an il~.A~I~ , and effective manner of achieving the desired function.
Forexample, theextensions 116and 118canbeprovidedwithl/.u~ ;o,ls 126 and 128, l~ . l.r, that cooperated with the edges of the slot 108 of the fLxture 106, as shown in Fig. 38. The IJlU~ 126 and 128 serve as means for wedging the extensions 126 and 128 tightly between the edga of the slot 10 -WO 95/222X7 PCTII1S~IO2027 i. ., ; ' .J
2 1 ~34 6~
ensuring that the lens ~ id6~ is tightly held closed during the insertion operation. Further, the ~,.uL,. again provide means for also aligning the extensions 116 and 118 providing the benefit described above with respect to alignment of the extension 126 and 128 to prevent damage to the intraocular lens.
S The 1~ 126 and 128 resiliently, and possibly plastically deform to some extent during wedging utilizing the resilient properties of the plastic material of the lens 'g 100 to hold the lens holding portion 102 tightly closed and the extensions 116 and 118 acculately aligned.
The ~ JLL ' 126 and 128 can be in the form of strips, dots, squares or other shaped ~ o;~ extending from the surfaces of the the extensions 116 and 118.
Claims (32)
1. A lens microcartridge for use with a surgical device for implantation of a deformable intraocular lens into the eye through a relatively small incision made in the ocular tissue, said lens microcartridge comprising:
a lens holder portion;
a nozzle portion connected to and extending from said lens holder portion, said lens holder portion and said nozzle portion having a continuous passageway extending therethrough, said passageway having at least one groove extending along at least a portion of the length of said passageway for manipulating the deformable introcular lens as it passes through the lens microcartridge.
a lens holder portion;
a nozzle portion connected to and extending from said lens holder portion, said lens holder portion and said nozzle portion having a continuous passageway extending therethrough, said passageway having at least one groove extending along at least a portion of the length of said passageway for manipulating the deformable introcular lens as it passes through the lens microcartridge.
2. A lens microcartridge according to Claim 1, wherein said groove varies in depth in a direction along the length of said passageway.
3. A lens microcartidge according to Claim 2, wherein said groove tapers in depth in a direction along the length of said passageway.
4. A lens microcartridge according to Claim 3, wherein said groove tapers from deeper in said lens holder portion to shallower in said nozzle portion.
5. A lens microcartridge according to Claim 1, wherein said passageway is provided with a set of opposed grooves extending along at least a portion of thelength of said bore.
6. A lens microcartridge according to Claim 1, wherein at least one of said grooves varies in depth in a direction along the length of said passageway.
7. A lens microcartidge according to Claim 6, wherein said at least one groove tapers in depth in a direction along the length of said passageway.
8. A lens microcartridge according to Claim 7, wherein said at least one groove tapers from deeper in said lens holder portion to shallower in said nozzle portion.
9. A lens microcartridge according to Claim 8, wherein both said grooves taper from deeper in said lens holder portion to shallower in said nozzle portion.
10. A lens microcartridge according to Claim 9, wherein said grooves extend through a least a portion of said lens holder portion and said nozzle portion.
11. A lens microcartridge according to Claim 1, wherein said groove extends through a least a portion of said lens holder portion and said nozzle portion.
12. A lens microcartridge according to Claim 1, wherein said lens holder portionand said nozzle portion define a one piece structure.
13. A lens microcartridge according to Claim 1, wherein said nozzle portion includes a tapered end for facilitating entry of the nozzle portion through the incision in the ocular tissue.
14. A lens microcartridge according to Claim 1, wherein said lens microcartridgeis configured to open for loading the deformable intraocular lens into said lenslens microcartridge, and close for inserting said lens microcartridge into the device for implantation of the deformable introcular lens.
15. A lens microcartridge according to Claim 14, wherein said lens microcartridge is configured to deform the deformable intraocular lens when closing to condense the configuration of the deformable intraocular lens to passthrough said nozzle portion for implanting the lens through the incision in the ocular tissue.
16. A lens microcartridge according to Claim 15, wherein the deformable intraocular lens is placed into a curved folded configuration within said passageway in said lens microcartridge leading to said nozzle portion when said lens holder portion is closed.
17. A lens microcartridge according to Claim 16, wherein said lens holder portion comprises a split tubular member defining a portion of said passageway and connected to said nozzle portion, said split tubular member can be opened toinsert the deformable intraocular lens and closed to insert the lens microcartridge into the device for implantation of the deformable introcular lens.
18. A lens microcartridge according to Claim 17, wherein said split tubular member is defined by a fixed tubular portion and a moveable tubular portion connected together at a hinge, said fixed tubular portion is connected to said nozzle portion and said moveable tubular portion moves relative to said nozzle portion.
19. A lens microcartridge according to Claim 18, wherein said hinge is definedby a decrease in wall thickness at a joint between said fixed tubular portion and said moveable tubular portion.
20. A lens microcartridge according to Claim 18, wherein said fixed tubular portion includes an extension and said moveable tubular portion includes an extension, said extensions are moved apart to open said lens holding portion forloading the deformable intraocular lens and moved together to fold the deformable intraocular lens and close said lens holding portion for inserting the lens microcartridge into the device for implantation of the deformable introcular lens.
21. A lens microcartridge according to Claim 1, wherein the lens microcartridge is made of disposable surgically acceptable plastic.
22. A lens microcartridge according to Claim 1, wherein a cross section of said nozzle portion is one selected from the group of circular, oval and two half circles set apart and connected together.
23. A lens microcartridge according to Claim 1, wherein a tip of said nozzle portion is provided with slots for allowing expansion of said passageway.
24. A lens microcartridge according to Claim 1, wherein said passageway is provided with a pair of opposed grooves.
25. A lens microcartridge according to Claim 1, wherein said lens holder portionis provided with grooves in said passageway to facilitate folding of the deformable intraocular lens being loaded.
26. A lens microcartridge according to Claim 24, wherein said lens holder portion is provided with grooves in said passageway therethrough to facilitate folding of the deformable intraocular lens being loaded.
27. A lens microcartridge according to Claim 26, wherein said grooves in said lens holder portion for facilitating folding of the deformable intraocular lens define a portion of said pair of opposed grooves.
28. A lens microcartridge according to Claim 20, wherein said extensions are provide with alignment means for maintaining alignment of said extensions when said lens holding portion is closed.
29. A lens microcartridge according to Claim 28, wherein said alignment means is defined by an alignment groove in one extension cooperating with an alignmentnib in the other extension when said lens holding portion is closed.
30. A lens microcartridge according to Claim 29, wherein said alignment groove and said alignment nib extend the full length of said extensions.
31. A lens microcartridge according to Claim 20, wherein the lens microcartridge is provided with means for tightly holding the lens microcartridge closed when installed in the device for insertion of the deformable intraocular lens.
32. A lens microcartridge according to Claim 31, wherein said means for tighly holding the lens microcartridge closed is define by protrusions provided on saidextension, said protrusions cooperating with surfaces of the device for insertion for wedging said extensions together.
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US08/197,604 | 1994-02-17 | ||
| US08/197,604 US5499987A (en) | 1992-09-30 | 1994-02-17 | Deformable intraocular lens cartridge |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| CA2183462A1 true CA2183462A1 (en) | 1995-08-24 |
Family
ID=22730048
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| CA002183462A Abandoned CA2183462A1 (en) | 1994-02-17 | 1995-02-17 | Intraocular lens microcartridge |
Country Status (12)
| Country | Link |
|---|---|
| US (1) | US5499987A (en) |
| EP (1) | EP0901343B1 (en) |
| JP (1) | JP3687973B2 (en) |
| KR (1) | KR100396038B1 (en) |
| CN (1) | CN1145580A (en) |
| AT (1) | ATE247926T1 (en) |
| AU (1) | AU1846395A (en) |
| CA (1) | CA2183462A1 (en) |
| DE (1) | DE69531636T2 (en) |
| ES (1) | ES2206495T3 (en) |
| NZ (1) | NZ281501A (en) |
| WO (1) | WO1995022287A1 (en) |
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| US4702244A (en) * | 1982-02-05 | 1987-10-27 | Staar Surgical Company | Surgical device for implantation of a deformable intraocular lens |
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-
1994
- 1994-02-17 US US08/197,604 patent/US5499987A/en not_active Expired - Lifetime
-
1995
- 1995-02-17 ES ES95910293T patent/ES2206495T3/en not_active Expired - Lifetime
- 1995-02-17 KR KR1019960704467A patent/KR100396038B1/en not_active IP Right Cessation
- 1995-02-17 AT AT95910293T patent/ATE247926T1/en not_active IP Right Cessation
- 1995-02-17 EP EP95910293A patent/EP0901343B1/en not_active Expired - Lifetime
- 1995-02-17 WO PCT/US1995/002027 patent/WO1995022287A1/en active IP Right Grant
- 1995-02-17 DE DE69531636T patent/DE69531636T2/en not_active Expired - Fee Related
- 1995-02-17 JP JP52193395A patent/JP3687973B2/en not_active Expired - Lifetime
- 1995-02-17 CN CN95192463A patent/CN1145580A/en active Pending
- 1995-02-17 CA CA002183462A patent/CA2183462A1/en not_active Abandoned
- 1995-02-17 NZ NZ281501A patent/NZ281501A/en unknown
- 1995-02-17 AU AU18463/95A patent/AU1846395A/en not_active Abandoned
Also Published As
| Publication number | Publication date |
|---|---|
| WO1995022287A1 (en) | 1995-08-24 |
| ES2206495T3 (en) | 2004-05-16 |
| NZ281501A (en) | 1998-09-24 |
| EP0901343A4 (en) | 1999-03-17 |
| EP0901343B1 (en) | 2003-08-27 |
| CN1145580A (en) | 1997-03-19 |
| JPH09509086A (en) | 1997-09-16 |
| AU1846395A (en) | 1995-09-04 |
| DE69531636T2 (en) | 2004-06-17 |
| EP0901343A1 (en) | 1999-03-17 |
| DE69531636D1 (en) | 2003-10-02 |
| ATE247926T1 (en) | 2003-09-15 |
| JP3687973B2 (en) | 2005-08-24 |
| US5499987A (en) | 1996-03-19 |
| KR100396038B1 (en) | 2004-03-24 |
| KR970701018A (en) | 1997-03-17 |
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| Date | Code | Title | Description |
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| EEER | Examination request | ||
| FZDE | Discontinued |