CA2197941A1 - A pharmaceutical tablet characterized by a showing high volume increase when coming into contact with biological fluids - Google Patents

A pharmaceutical tablet characterized by a showing high volume increase when coming into contact with biological fluids

Info

Publication number
CA2197941A1
CA2197941A1 CA002197941A CA2197941A CA2197941A1 CA 2197941 A1 CA2197941 A1 CA 2197941A1 CA 002197941 A CA002197941 A CA 002197941A CA 2197941 A CA2197941 A CA 2197941A CA 2197941 A1 CA2197941 A1 CA 2197941A1
Authority
CA
Canada
Prior art keywords
contact
coming
high volume
biological fluids
volume increase
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Granted
Application number
CA002197941A
Other languages
French (fr)
Other versions
CA2197941C (en
Inventor
Ubaldo Conte
Lauretta Maggi
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Jagotec AG
Original Assignee
Jagotec AG
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Jagotec AG filed Critical Jagotec AG
Publication of CA2197941A1 publication Critical patent/CA2197941A1/en
Application granted granted Critical
Publication of CA2197941C publication Critical patent/CA2197941C/en
Anticipated expiration legal-status Critical
Expired - Lifetime legal-status Critical Current

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/20—Pills, tablets, discs, rods
    • A61K9/2072—Pills, tablets, discs, rods characterised by shape, structure or size; Tablets with holes, special break lines or identification marks; Partially coated tablets; Disintegrating flat shaped forms
    • A61K9/2086—Layered tablets, e.g. bilayer tablets; Tablets of the type inert core-active coat

Abstract

A description is given of a pharmaceutical form for oral administration consisting of a two- or three-layers tablet, wherein at least one layer can rapidly swell by contact with biological and/or aqueous fluids, said swelling resulting in a considerable increase in the tablet volume. Said phenomenon determines a prolonged residence of the pharmaceutical form at the gastric level and therefore allows a slow release of the active ingredient from said pharmaceutical form to the stomach and/or the first tract of the intestine.
CA002197941A 1996-02-19 1997-02-19 A pharmaceutical tablet characterized by a showing high volume increase when coming into contact with biological fluids Expired - Lifetime CA2197941C (en)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
IT96MI000311A IT1282650B1 (en) 1996-02-19 1996-02-19 PHARMACEUTICAL TABLET, CHARACTERIZED BY A HIGH INCREASE IN VOLUME IN CONTACT WITH BIOLOGICAL LIQUIDS
ITMI96A000311 1996-02-19

Publications (2)

Publication Number Publication Date
CA2197941A1 true CA2197941A1 (en) 1997-08-20
CA2197941C CA2197941C (en) 2001-12-04

Family

ID=11373320

Family Applications (1)

Application Number Title Priority Date Filing Date
CA002197941A Expired - Lifetime CA2197941C (en) 1996-02-19 1997-02-19 A pharmaceutical tablet characterized by a showing high volume increase when coming into contact with biological fluids

Country Status (12)

Country Link
US (1) US5780057A (en)
EP (2) EP0795324B1 (en)
JP (1) JP3251190B2 (en)
AT (2) ATE530173T1 (en)
AU (1) AU719170B2 (en)
CA (1) CA2197941C (en)
DE (1) DE69728710T2 (en)
DK (1) DK0795324T3 (en)
ES (2) ES2219709T3 (en)
IT (1) IT1282650B1 (en)
NZ (1) NZ314265A (en)
PT (1) PT795324E (en)

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US6046177A (en) * 1997-05-05 2000-04-04 Cydex, Inc. Sulfoalkyl ether cyclodextrin based controlled release solid pharmaceutical formulations
WO2007132296A3 (en) * 2005-12-30 2008-03-27 Intelgenx Corp Multilayer tablet
US9717682B2 (en) 2009-12-08 2017-08-01 Intelgenx Corporation Solid oral film dosage forms and methods for making same
US10610528B2 (en) 2009-12-08 2020-04-07 Intelgenx Corp. Solid oral film dosage forms and methods for making same

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Cited By (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US6046177A (en) * 1997-05-05 2000-04-04 Cydex, Inc. Sulfoalkyl ether cyclodextrin based controlled release solid pharmaceutical formulations
WO2007132296A3 (en) * 2005-12-30 2008-03-27 Intelgenx Corp Multilayer tablet
US8691272B2 (en) 2005-12-30 2014-04-08 Intelgenx Corp. Multilayer tablet
US9717682B2 (en) 2009-12-08 2017-08-01 Intelgenx Corporation Solid oral film dosage forms and methods for making same
US10610528B2 (en) 2009-12-08 2020-04-07 Intelgenx Corp. Solid oral film dosage forms and methods for making same

Also Published As

Publication number Publication date
CA2197941C (en) 2001-12-04
AU1477697A (en) 1997-08-28
EP0795324A3 (en) 1998-11-04
ES2376199T3 (en) 2012-03-09
AU719170B2 (en) 2000-05-04
JPH09316005A (en) 1997-12-09
EP1382331B1 (en) 2011-10-26
DE69728710T2 (en) 2005-04-07
NZ314265A (en) 1997-07-27
IT1282650B1 (en) 1998-03-31
ES2376199T8 (en) 2012-04-04
PT795324E (en) 2004-09-30
ES2219709T3 (en) 2004-12-01
ATE264670T1 (en) 2004-05-15
EP0795324B1 (en) 2004-04-21
EP0795324A2 (en) 1997-09-17
DK0795324T3 (en) 2004-08-16
ITMI960311A1 (en) 1997-08-19
EP1382331A1 (en) 2004-01-21
JP3251190B2 (en) 2002-01-28
ATE530173T1 (en) 2011-11-15
DE69728710D1 (en) 2004-05-27
US5780057A (en) 1998-07-14
ITMI960311A0 (en) 1996-02-19

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