CA2198357A1 - Electrotransport system with remote telemetry link - Google Patents

Electrotransport system with remote telemetry link

Info

Publication number
CA2198357A1
CA2198357A1 CA002198357A CA2198357A CA2198357A1 CA 2198357 A1 CA2198357 A1 CA 2198357A1 CA 002198357 A CA002198357 A CA 002198357A CA 2198357 A CA2198357 A CA 2198357A CA 2198357 A1 CA2198357 A1 CA 2198357A1
Authority
CA
Canada
Prior art keywords
delivery unit
telemetry link
control unit
transmitted
unit
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Granted
Application number
CA002198357A
Other languages
French (fr)
Other versions
CA2198357C (en
Inventor
Gary A. Lattin
Thomas A. Riddle
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Alza Corp
Original Assignee
Gary A. Lattin
Thomas A. Riddle
Alza Corporation
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Gary A. Lattin, Thomas A. Riddle, Alza Corporation filed Critical Gary A. Lattin
Publication of CA2198357A1 publication Critical patent/CA2198357A1/en
Application granted granted Critical
Publication of CA2198357C publication Critical patent/CA2198357C/en
Anticipated expiration legal-status Critical
Expired - Fee Related legal-status Critical Current

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B5/00—Measuring for diagnostic purposes; Identification of persons
    • A61B5/145—Measuring characteristics of blood in vivo, e.g. gas concentration, pH value; Measuring characteristics of body fluids or tissues, e.g. interstitial fluid, cerebral tissue
    • A61B5/14507—Measuring characteristics of blood in vivo, e.g. gas concentration, pH value; Measuring characteristics of body fluids or tissues, e.g. interstitial fluid, cerebral tissue specially adapted for measuring characteristics of body fluids other than blood
    • A61B5/1451—Measuring characteristics of blood in vivo, e.g. gas concentration, pH value; Measuring characteristics of body fluids or tissues, e.g. interstitial fluid, cerebral tissue specially adapted for measuring characteristics of body fluids other than blood for interstitial fluid
    • A61B5/14514—Measuring characteristics of blood in vivo, e.g. gas concentration, pH value; Measuring characteristics of body fluids or tissues, e.g. interstitial fluid, cerebral tissue specially adapted for measuring characteristics of body fluids other than blood for interstitial fluid using means for aiding extraction of interstitial fluid, e.g. microneedles or suction
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61N—ELECTROTHERAPY; MAGNETOTHERAPY; RADIATION THERAPY; ULTRASOUND THERAPY
    • A61N1/00—Electrotherapy; Circuits therefor
    • A61N1/18—Applying electric currents by contact electrodes
    • A61N1/20—Applying electric currents by contact electrodes continuous direct currents
    • A61N1/30—Apparatus for iontophoresis, i.e. transfer of media in ionic state by an electromotoric force into the body, or cataphoresis
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B5/00—Measuring for diagnostic purposes; Identification of persons
    • A61B5/145—Measuring characteristics of blood in vivo, e.g. gas concentration, pH value; Measuring characteristics of body fluids or tissues, e.g. interstitial fluid, cerebral tissue
    • A61B5/14532—Measuring characteristics of blood in vivo, e.g. gas concentration, pH value; Measuring characteristics of body fluids or tissues, e.g. interstitial fluid, cerebral tissue for measuring glucose, e.g. by tissue impedance measurement

Abstract

An electrotransport system (20) for delivering a therapeutic agent (36) through a body surface (40) (e.g., skin) of a patient includes a pair of electrodes (34, 38) for contacting the body surface, at least one of which contains the therapeutic agent (36). The system (20) is physically separated into a control unit (22) and a delivery unit (24) connected by a radiated energy signal-based telemetry link. The telemetry link may be radio frequency, ultrasonic, optical, infrared or inductively coupled. Signals from the control unit may be transmitted to the delivery unit by the telemetry link, or vice versa. The delivery unit may control electrotransport current on the signal transmitted.
The radiated energy signal may be encoded to improve immunity to extrinsic interference. The delivery unit (24) may be configured with sensor means for detecting a condition such as a body or system parameter reaching some predetermined limit. The delivery unit (24) may also have an additional telemetry link connecting to the control unit (22) for transmitting the system or body status condition to the control unit. Visual or audio indicators may be provided on the control unit (22) for indication of system or body status conditions detected and transmitted by the delivery unit (24).
CA002198357A 1994-10-31 1995-10-17 Electrotransport system with remote telemetry link Expired - Fee Related CA2198357C (en)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US08/332,322 US5551953A (en) 1994-10-31 1994-10-31 Electrotransport system with remote telemetry link
US08/332,322 1994-10-31
PCT/US1995/013218 WO1996013302A1 (en) 1994-10-31 1995-10-17 Electrotransport system with remote telemetry link

Publications (2)

Publication Number Publication Date
CA2198357A1 true CA2198357A1 (en) 1996-05-09
CA2198357C CA2198357C (en) 2005-08-16

Family

ID=23297717

Family Applications (1)

Application Number Title Priority Date Filing Date
CA002198357A Expired - Fee Related CA2198357C (en) 1994-10-31 1995-10-17 Electrotransport system with remote telemetry link

Country Status (11)

Country Link
US (1) US5551953A (en)
EP (1) EP0789603B1 (en)
JP (1) JPH10507948A (en)
KR (1) KR100382860B1 (en)
AT (1) ATE314113T1 (en)
AU (1) AU691987B2 (en)
CA (1) CA2198357C (en)
DE (1) DE69534722T2 (en)
DK (1) DK0789603T3 (en)
ES (1) ES2250975T3 (en)
WO (1) WO1996013302A1 (en)

Families Citing this family (181)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5876368A (en) * 1994-09-30 1999-03-02 Becton Dickinson And Company Iontophoretic drug delivery device having improved controller
SE9501678D0 (en) * 1995-05-05 1995-05-05 Siemens Elema Ab Device for transmitting information via patient tube in intensive care or anesthesia apparatus
US6086572A (en) * 1996-05-31 2000-07-11 Alza Corporation Electrotransport device and method of setting output
US5857994A (en) * 1996-10-01 1999-01-12 Becton, Dickinson And Company Awakenable iontophoretic/delivery device for reducing electrical sensation upon application thereof
US8734339B2 (en) 1996-12-16 2014-05-27 Ip Holdings, Inc. Electronic skin patch for real time monitoring of cardiac activity and personal health management
US5991655A (en) * 1997-03-03 1999-11-23 Drug Delivery Systems, Inc. Iontophoretic drug delivery device and method of manufacturing the same
US5899876A (en) * 1997-08-27 1999-05-04 Becton, Dickinson And Company Multiple site drug delivery system
US20010009983A1 (en) * 1997-09-29 2001-07-26 Drug Delivery Technologies, Inc. Methods for implementing current delivery profiles used in an iontophoretic system
WO1999023760A1 (en) * 1997-11-03 1999-05-14 Harris Corporation Receiver for a reconfigurable radio system and method therefor
US8688188B2 (en) 1998-04-30 2014-04-01 Abbott Diabetes Care Inc. Analyte monitoring device and methods of use
US6175752B1 (en) 1998-04-30 2001-01-16 Therasense, Inc. Analyte monitoring device and methods of use
US8465425B2 (en) 1998-04-30 2013-06-18 Abbott Diabetes Care Inc. Analyte monitoring device and methods of use
US8346337B2 (en) 1998-04-30 2013-01-01 Abbott Diabetes Care Inc. Analyte monitoring device and methods of use
US8480580B2 (en) 1998-04-30 2013-07-09 Abbott Diabetes Care Inc. Analyte monitoring device and methods of use
US6949816B2 (en) 2003-04-21 2005-09-27 Motorola, Inc. Semiconductor component having first surface area for electrically coupling to a semiconductor chip and second surface area for electrically coupling to a substrate, and method of manufacturing same
US8974386B2 (en) 1998-04-30 2015-03-10 Abbott Diabetes Care Inc. Analyte monitoring device and methods of use
US9066695B2 (en) 1998-04-30 2015-06-30 Abbott Diabetes Care Inc. Analyte monitoring device and methods of use
US6500165B1 (en) * 1998-10-29 2002-12-31 Steven R. Frank Active antisepsis device
IT1304052B1 (en) * 1998-12-23 2001-03-07 Fabio Paolo Marchesi ELECTRONIC STIMULATION EQUIPMENT WITH WIRELESS SATELLITE UNIT
US6317630B1 (en) * 1999-01-29 2001-11-13 Yossi Gross Drug delivery device
US6477410B1 (en) 2000-05-31 2002-11-05 Biophoretic Therapeutic Systems, Llc Electrokinetic delivery of medicaments
US6792306B2 (en) 2000-03-10 2004-09-14 Biophoretic Therapeutic Systems, Llc Finger-mounted electrokinetic delivery system for self-administration of medicaments and methods therefor
US6553253B1 (en) * 1999-03-12 2003-04-22 Biophoretic Therapeutic Systems, Llc Method and system for electrokinetic delivery of a substance
US6520950B1 (en) * 1999-05-10 2003-02-18 Genetronics, Inc. Method of electroporation-enhanced delivery of active agents
US7171264B1 (en) * 1999-05-10 2007-01-30 Genetronics, Inc. Intradermal delivery of active agents by needle-free injection and electroporation
US20040229295A1 (en) * 1999-05-17 2004-11-18 Marchitto Kevin S. Activated delivery of biomolecules using electromagnetic energy
EP1180053A4 (en) * 1999-05-17 2006-11-08 Kevin S Marchitto Remote and local controlled delivery of pharmaceutical compounds using electromagnetic energy
US6379324B1 (en) 1999-06-09 2002-04-30 The Procter & Gamble Company Intracutaneous microneedle array apparatus
US6312612B1 (en) 1999-06-09 2001-11-06 The Procter & Gamble Company Apparatus and method for manufacturing an intracutaneous microneedle array
US6256533B1 (en) * 1999-06-09 2001-07-03 The Procter & Gamble Company Apparatus and method for using an intracutaneous microneedle array
WO2000078207A2 (en) * 1999-06-22 2000-12-28 The Secretary Of State For Defence Analyte detection
US6969382B2 (en) * 1999-07-26 2005-11-29 Zuli Holdings, Ltd. Method and apparatus for treating bodily tissues with medicinal substance
US6334859B1 (en) * 1999-07-26 2002-01-01 Zuli Holdings Ltd. Subcutaneous apparatus and subcutaneous method for treating bodily tissues with electricity or medicaments
US6361522B1 (en) * 1999-10-21 2002-03-26 Cardiac Pacemakers, Inc. Drug delivery system for implantable cardiac device
DE60022540T2 (en) * 1999-11-15 2006-06-14 Velcro Ind FASTENING ELEMENT FOR THE SKIN
US6310556B1 (en) * 2000-02-14 2001-10-30 Sonic Innovations, Inc. Apparatus and method for detecting a low-battery power condition and generating a user perceptible warning
US6714816B1 (en) * 2000-02-22 2004-03-30 University Of South Florida Electroporation and electrophoresis system and method for achieving molecular penetration into cells in vivo
US6565532B1 (en) 2000-07-12 2003-05-20 The Procter & Gamble Company Microneedle apparatus used for marking skin and for dispensing semi-permanent subcutaneous makeup
US6699188B2 (en) 2000-06-22 2004-03-02 Guidance Interactive Technologies Interactive reward devices and methods
WO2002013671A2 (en) * 2000-08-14 2002-02-21 Pharmacia Corporation Drug release (delivery system)
US7616997B2 (en) 2000-09-27 2009-11-10 Kieval Robert S Devices and methods for cardiovascular reflex control via coupled electrodes
US7499742B2 (en) 2001-09-26 2009-03-03 Cvrx, Inc. Electrode structures and methods for their use in cardiovascular reflex control
US7840271B2 (en) 2000-09-27 2010-11-23 Cvrx, Inc. Stimulus regimens for cardiovascular reflex control
US7623926B2 (en) 2000-09-27 2009-11-24 Cvrx, Inc. Stimulus regimens for cardiovascular reflex control
US8086314B1 (en) 2000-09-27 2011-12-27 Cvrx, Inc. Devices and methods for cardiovascular reflex control
US20120191052A1 (en) 2000-10-06 2012-07-26 Ip Holdings, Inc. Intelligent activated skin patch system
US7828827B2 (en) 2002-05-24 2010-11-09 Corium International, Inc. Method of exfoliation of skin using closely-packed microstructures
US7131987B2 (en) * 2000-10-16 2006-11-07 Corium International, Inc. Microstructures and method for treating and conditioning skin which cause less irritation during exfoliation
US7108681B2 (en) 2000-10-16 2006-09-19 Corium International, Inc. Microstructures for delivering a composition cutaneously to skin
US6748089B1 (en) 2000-10-17 2004-06-08 Sonic Innovations, Inc. Switch responsive to an audio cue
US7369890B2 (en) 2000-11-02 2008-05-06 Cardiac Pacemakers, Inc. Technique for discriminating between coordinated and uncoordinated cardiac rhythms
US6689117B2 (en) 2000-12-18 2004-02-10 Cardiac Pacemakers, Inc. Drug delivery system for implantable medical device
ATE311811T1 (en) * 2000-12-21 2005-12-15 Insulet Corp REMOTE CONTROL MEDICAL DEVICE
US6560471B1 (en) 2001-01-02 2003-05-06 Therasense, Inc. Analyte monitoring device and methods of use
CA2478614C (en) * 2001-03-13 2013-01-15 University Of South Florida Electromanipulation device and method
US6663820B2 (en) 2001-03-14 2003-12-16 The Procter & Gamble Company Method of manufacturing microneedle structures using soft lithography and photolithography
DK1390099T3 (en) * 2001-04-27 2008-06-09 Transport Pharmaceuticals Inc System for electrokinetic delivery of substance
EP1385575A1 (en) * 2001-04-30 2004-02-04 Medtronic, Inc. Transcutaneous monitor and method of use, using therapeutic output from an implanted medical device
US6591124B2 (en) 2001-05-11 2003-07-08 The Procter & Gamble Company Portable interstitial fluid monitoring system
US7493162B2 (en) * 2001-06-15 2009-02-17 Cardiac Pacemakers, Inc. Pulmonary vein stent for treating atrial fibrillation
US7209783B2 (en) * 2001-06-15 2007-04-24 Cardiac Pacemakers, Inc. Ablation stent for treating atrial fibrillation
US20040087992A1 (en) * 2002-08-09 2004-05-06 Vladimir Gartstein Microstructures for delivering a composition cutaneously to skin using rotatable structures
US7340303B2 (en) 2001-09-25 2008-03-04 Cardiac Pacemakers, Inc. Evoked response sensing for ischemia detection
WO2003049806A1 (en) * 2001-12-06 2003-06-19 Bio-Rad Laboratories, Inc. Automatic electroporation optimization system
US7493168B2 (en) * 2002-02-01 2009-02-17 The Cleveland Clinic Foundation Electrical stimulation to treat hair loss
AU2003225128A1 (en) * 2002-04-24 2003-11-10 Stephen T. Flock Feedback control device for transcutaneous drug delivery and uses therefor
WO2003092764A2 (en) * 2002-04-29 2003-11-13 Kevin Marchitto Controlled release transdermal drug delivery
US6761561B2 (en) 2002-06-07 2004-07-13 Schick Technologies Wireless dental camera
US7089055B2 (en) * 2002-06-28 2006-08-08 Cardiac Pacemakers, Inc. Method and apparatus for delivering pre-shock defibrillation therapy
US7072443B2 (en) * 2002-10-03 2006-07-04 Schick Technologies, Inc. Intraoral image sensor
US6972411B2 (en) * 2002-10-03 2005-12-06 Schick Technologies, Inc. Method of event detection for intraoral image sensor
US7072711B2 (en) 2002-11-12 2006-07-04 Cardiac Pacemakers, Inc. Implantable device for delivering cardiac drug therapy
US20040267240A1 (en) * 2003-01-29 2004-12-30 Yossi Gross Active drug delivery in the gastrointestinal tract
US20050058701A1 (en) * 2003-01-29 2005-03-17 Yossi Gross Active drug delivery in the gastrointestinal tract
JP2006517827A (en) * 2003-01-29 2006-08-03 イー−ピル・ファーマ・リミテッド Delivery of active drugs in the gastrointestinal tract
US6908307B2 (en) 2003-02-03 2005-06-21 Schick Technologies Dental camera utilizing multiple lenses
US7578954B2 (en) * 2003-02-24 2009-08-25 Corium International, Inc. Method for manufacturing microstructures having multiple microelements with through-holes
US7320675B2 (en) 2003-08-21 2008-01-22 Cardiac Pacemakers, Inc. Method and apparatus for modulating cellular metabolism during post-ischemia or heart failure
DE10354833A1 (en) * 2003-11-24 2005-06-23 Liedtke, Rainer K., Dr. Dermal diagnostic patch systems with active transponders
US8017145B2 (en) * 2003-12-22 2011-09-13 Conopco, Inc. Exfoliating personal care wipe article containing an array of projections
US7840263B2 (en) 2004-02-27 2010-11-23 Cardiac Pacemakers, Inc. Method and apparatus for device controlled gene expression
WO2005084275A2 (en) 2004-02-27 2005-09-15 Iomed, Inc. Iontophoretic electrode
CA2560840C (en) 2004-03-24 2014-05-06 Corium International, Inc. Transdermal delivery device
US8092549B2 (en) 2004-09-24 2012-01-10 The Invention Science Fund I, Llc Ciliated stent-like-system
US7850676B2 (en) 2004-04-19 2010-12-14 The Invention Science Fund I, Llc System with a reservoir for perfusion management
US7998060B2 (en) 2004-04-19 2011-08-16 The Invention Science Fund I, Llc Lumen-traveling delivery device
US8024036B2 (en) 2007-03-19 2011-09-20 The Invention Science Fund I, Llc Lumen-traveling biological interface device and method of use
US8361013B2 (en) 2004-04-19 2013-01-29 The Invention Science Fund I, Llc Telescoping perfusion management system
US9011329B2 (en) 2004-04-19 2015-04-21 Searete Llc Lumenally-active device
US8337482B2 (en) 2004-04-19 2012-12-25 The Invention Science Fund I, Llc System for perfusion management
US8353896B2 (en) * 2004-04-19 2013-01-15 The Invention Science Fund I, Llc Controllable release nasal system
US9801527B2 (en) 2004-04-19 2017-10-31 Gearbox, Llc Lumen-traveling biological interface device
US8000784B2 (en) * 2004-04-19 2011-08-16 The Invention Science Fund I, Llc Lumen-traveling device
US7764995B2 (en) 2004-06-07 2010-07-27 Cardiac Pacemakers, Inc. Method and apparatus to modulate cellular regeneration post myocardial infarct
US7567841B2 (en) 2004-08-20 2009-07-28 Cardiac Pacemakers, Inc. Method and apparatus for delivering combined electrical and drug therapies
GB0419238D0 (en) * 2004-08-28 2004-09-29 Univ Manchester Dysphagia recovery
US7205701B2 (en) * 2004-09-03 2007-04-17 Honeywell International Inc. Passive wireless acoustic wave chemical sensor
US7981065B2 (en) 2004-12-20 2011-07-19 Cardiac Pacemakers, Inc. Lead electrode incorporating extracellular matrix
US8060219B2 (en) 2004-12-20 2011-11-15 Cardiac Pacemakers, Inc. Epicardial patch including isolated extracellular matrix with pacing electrodes
US7499748B2 (en) 2005-04-11 2009-03-03 Cardiac Pacemakers, Inc. Transvascular neural stimulation device
US7617003B2 (en) * 2005-05-16 2009-11-10 Cardiac Pacemakers, Inc. System for selective activation of a nerve trunk using a transvascular reshaping lead
WO2006123346A2 (en) * 2005-05-19 2006-11-23 E-Pill Pharma, Ltd. Ingestible device for nitric oxide production in tissue
US8295922B2 (en) 2005-08-08 2012-10-23 Tti Ellebeau, Inc. Iontophoresis device
US8386030B2 (en) 2005-08-08 2013-02-26 Tti Ellebeau, Inc. Iontophoresis device
US20070088331A1 (en) * 2005-08-18 2007-04-19 Transcutaneous Technologies Inc. Method and apparatus for managing active agent usage, and active agent injecting device
US20070088332A1 (en) * 2005-08-22 2007-04-19 Transcutaneous Technologies Inc. Iontophoresis device
WO2007023907A1 (en) * 2005-08-24 2007-03-01 Transcu Ltd. Refrigeration-type electrode structure for iontophoresis
BRPI0616165A2 (en) 2005-09-15 2011-06-07 Tti Ellebeau Inc rod type iontophoresis device
US7616990B2 (en) 2005-10-24 2009-11-10 Cardiac Pacemakers, Inc. Implantable and rechargeable neural stimulator
US20080015422A1 (en) * 2005-12-29 2008-01-17 Guidance Interactive Healthcare, Inc. Combined peripheral and health monitoring devices
US20070179356A1 (en) * 2005-12-29 2007-08-02 Guidance Interactive Healthcare, Inc. Programmable devices, systems and methods for encouraging the monitoring of medical parameters
US9198563B2 (en) * 2006-04-12 2015-12-01 The Invention Science Fund I, Llc Temporal control of a lumen traveling device in a body tube tree
US20080058788A1 (en) 2006-04-12 2008-03-06 Searete Llc., A Limited Liability Corporation Of The State Of Delaware Autofluorescent imaging and target ablation
CN101496042A (en) 2006-05-02 2009-07-29 普罗秋斯生物医学公司 Patient customized therapeutic regimens
US7920907B2 (en) 2006-06-07 2011-04-05 Abbott Diabetes Care Inc. Analyte monitoring system and method
JP5250549B2 (en) 2006-06-19 2013-07-31 ハイランド インストゥルメンツ， インコーポレイテッド Apparatus and method for stimulation of biological tissue
US9623241B2 (en) 2006-06-19 2017-04-18 Highland Instruments Treatment methods
US9913976B2 (en) 2006-06-19 2018-03-13 Highland Instruments, Inc. Systems and methods for stimulating and monitoring biological tissue
US8718758B2 (en) * 2006-06-19 2014-05-06 Highland Instruments, Inc. Interface apparatus for stimulation of biological tissue
US20080077076A1 (en) * 2006-08-29 2008-03-27 Transcutaneous Technologies Inc. Iontophoresis device and method for operation with a usb (universal serial bus) power source
JP5916277B2 (en) 2006-10-25 2016-05-11 プロテウス デジタル ヘルス， インコーポレイテッド Ingestible control activation identifier
CA2671069A1 (en) 2006-12-01 2008-06-12 Tti Ellebeau, Inc. Systems, devices, and methods for powering and/or controlling devices, for instance transdermal delivery devices
CA2676221C (en) 2007-01-22 2016-12-20 Corium International, Inc. Applicators for microneedles
MY165368A (en) 2007-02-01 2018-03-21 Proteus Digital Health Inc Ingestible event marker systems
EP3236524A1 (en) 2007-02-14 2017-10-25 Proteus Digital Health, Inc. In-body power source having high surface area electrode
US9114238B2 (en) 2007-04-16 2015-08-25 Corium International, Inc. Solvent-cast microprotrusion arrays containing active ingredient
AU2008242142A1 (en) * 2007-04-19 2008-10-30 C.G.M.3 Ltd Device system and method for monitoring and controlling blood analyte levels
US7998110B2 (en) * 2007-04-25 2011-08-16 Hong Kong Polytechnic University Medical device for delivering drug and/or performing physical therapy
US8540632B2 (en) 2007-05-24 2013-09-24 Proteus Digital Health, Inc. Low profile antenna for in body device
EP2178598A4 (en) * 2007-08-17 2012-08-15 Isis Biopolymer Llc Iontophoretic drug delivery system
WO2009048607A1 (en) 2007-10-10 2009-04-16 Corium International, Inc. Vaccine delivery via microneedle arrays
WO2009076363A1 (en) * 2007-12-10 2009-06-18 Isis Biopolymer Llc Iontophoretic drug delivery device and software application
US8369942B2 (en) * 2008-03-20 2013-02-05 The Invention Science Fund I, Llc Subdermal material delivery device
SG10201702853UA (en) 2008-07-08 2017-06-29 Proteus Digital Health Inc Ingestible event marker data framework
JP5888645B2 (en) * 2008-12-30 2016-03-22 テバ・ファーマシューティカルズ・インターナショナル・ゲー・エム・ベー・ハー Electronic control of drug administration system
SG172846A1 (en) 2009-01-06 2011-08-29 Proteus Biomedical Inc Ingestion-related biofeedback and personalized medical therapy method and system
JP5457042B2 (en) * 2009-01-29 2014-04-02 テルモ株式会社 Transdermal drug delivery system
US20100286587A1 (en) * 2009-05-07 2010-11-11 Yossi Gross Sublingual electrical drug delivery
US8414559B2 (en) 2009-05-07 2013-04-09 Rainbow Medical Ltd. Gastroretentive duodenal pill
US20110092881A1 (en) * 2009-05-08 2011-04-21 Isis Biopolymer Inc. Iontophoretic device with contact sensor
US20100286590A1 (en) * 2009-05-08 2010-11-11 Isis Biopolymer Llc Iontophoretic device with improved counterelectrode
DE202009012183U1 (en) * 2009-09-08 2009-11-26 Bürkert Werke GmbH & Co. KG Manually actuable control module
TWI517050B (en) 2009-11-04 2016-01-11 普羅托斯數位健康公司 System for supply chain management
AU2011248108B2 (en) 2010-05-04 2016-05-26 Corium Pharma Solutions, Inc. Method and device for transdermal delivery of parathyroid hormone using a microprojection array
TWI557672B (en) * 2010-05-19 2016-11-11 波提亞斯數位康健公司 Computer system and computer-implemented method to track medication from manufacturer to a patient, apparatus and method for confirming delivery of medication to a patient, patient interface device
US8509882B2 (en) 2010-06-08 2013-08-13 Alivecor, Inc. Heart monitoring system usable with a smartphone or computer
US9351654B2 (en) 2010-06-08 2016-05-31 Alivecor, Inc. Two electrode apparatus and methods for twelve lead ECG
US8700137B2 (en) 2012-08-30 2014-04-15 Alivecor, Inc. Cardiac performance monitoring system for use with mobile communications devices
WO2012054560A1 (en) 2010-10-21 2012-04-26 Highland Instruments, Inc. Methods for detecting a condition
US8428708B1 (en) 2012-05-21 2013-04-23 Incline Therapeutics, Inc. Self-test for analgesic product
US8428709B1 (en) 2012-06-11 2013-04-23 Incline Therapeutics, Inc. Current control for electrotransport drug delivery
US8301238B2 (en) * 2011-03-31 2012-10-30 Incline Therapeutics, Inc. Two-part electrotransport device
US9011510B2 (en) 2011-05-09 2015-04-21 The Invention Science Fund I, Llc Method, device and system for modulating an activity of brown adipose tissue in a vertebrate subject
US9238133B2 (en) 2011-05-09 2016-01-19 The Invention Science Fund I, Llc Method, device and system for modulating an activity of brown adipose tissue in a vertebrate subject
WO2015112603A1 (en) 2014-01-21 2015-07-30 Proteus Digital Health, Inc. Masticable ingestible product and communication system therefor
RU2014106126A (en) 2011-07-21 2015-08-27 Протеус Диджитал Хелс, Инк. DEVICE, SYSTEM AND METHOD OF MOBILE COMMUNICATION
DE202012002019U1 (en) * 2012-02-27 2012-04-03 Bürkert Werke GmbH Manually actuable control module
US8761717B1 (en) 2012-08-07 2014-06-24 Brian K. Buchheit Safety feature to disable an electronic device when a wireless implantable medical device (IMD) is proximate
WO2014074913A1 (en) 2012-11-08 2014-05-15 Alivecor, Inc. Electrocardiogram signal detection
US20160279434A1 (en) * 2012-11-14 2016-09-29 International Scientific Pty Ltd A device, system, method, computer program and data signal for the control of a transdermal delivery device
MX2015008157A (en) 2012-12-21 2016-02-22 Corium Int Inc Microarray for delivery of therapeutic agent and methods of use.
WO2014107700A1 (en) 2013-01-07 2014-07-10 Alivecor, Inc. Methods and systems for electrode placement
FR3000897B1 (en) * 2013-01-14 2016-10-28 Feeligreen AUTORGANIZED ELECTROSTIMULATION AND / OR IONTOPHORESIS DEVICE
EP4094799A1 (en) 2013-03-12 2022-11-30 Corium, Inc. Microprojection applicators
US10195409B2 (en) 2013-03-15 2019-02-05 Corium International, Inc. Multiple impact microprojection applicators and methods of use
RU2711567C2 (en) 2013-03-15 2020-01-17 Кориум, ИНК. Microchip for drug delivery and methods for use thereof
JP2016514133A (en) 2013-03-15 2016-05-19 コリウム インターナショナル， インコーポレイテッド MICROARRAY CONTAINING FINE STRUCTURE CONTAINING NO POLYMER, MANUFACTURING METHOD AND USE METHOD
US9254092B2 (en) 2013-03-15 2016-02-09 Alivecor, Inc. Systems and methods for processing and analyzing medical data
CA2903583C (en) 2013-03-15 2021-12-28 Corium International, Inc. Microarray for delivery of therapeutic agent, methods of use, and methods of making
EP3005281A4 (en) 2013-06-04 2017-06-28 Proteus Digital Health, Inc. System, apparatus and methods for data collection and assessing outcomes
US9247911B2 (en) 2013-07-10 2016-02-02 Alivecor, Inc. Devices and methods for real-time denoising of electrocardiograms
US10084880B2 (en) 2013-11-04 2018-09-25 Proteus Digital Health, Inc. Social media networking based on physiologic information
US9420956B2 (en) 2013-12-12 2016-08-23 Alivecor, Inc. Methods and systems for arrhythmia tracking and scoring
US10624843B2 (en) 2014-09-04 2020-04-21 Corium, Inc. Microstructure array, methods of making, and methods of use
USD759803S1 (en) 2014-10-28 2016-06-21 Highland Instruments, Inc. Adjustable headpiece with anatomical markers
GB2532044A (en) 2014-11-06 2016-05-11 Phagenesis Ltd Catheter for recovery of dysphagia
WO2016182919A1 (en) * 2015-05-08 2016-11-17 University Of Tennessee Research Foundation Wireless patch system for transdermal, transmucosal and dental electrical drug delivery
JP6498325B2 (en) 2015-05-13 2019-04-10 アライヴコア・インコーポレーテッド Discrepancy monitoring
WO2017004067A1 (en) 2015-06-29 2017-01-05 Corium International, Inc. Microarray for delivery of therapeutic agent, methods of use, and methods of making
US10716896B2 (en) 2015-11-24 2020-07-21 Insulet Corporation Wearable automated medication delivery system
TWI728155B (en) 2016-07-22 2021-05-21 日商大塚製藥股份有限公司 Electromagnetic sensing and detection of ingestible event markers

Family Cites Families (36)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US3991755A (en) * 1973-07-27 1976-11-16 Medicon, Inc. Iontophoresis apparatus for applying local anesthetics
US4141359A (en) * 1976-08-16 1979-02-27 University Of Utah Epidermal iontophoresis device
US4559037A (en) * 1977-12-28 1985-12-17 Siemens Aktiengesellschaft Device for the pre-programmable infusion of liquids
FR2420979A1 (en) * 1978-03-28 1979-10-26 Guillot Jacqueline ELECTROCONDUCTOR MOLDING
US4619653A (en) * 1979-04-27 1986-10-28 The Johns Hopkins University Apparatus for detecting at least one predetermined condition and providing an informational signal in response thereto in a medication infusion system
US4281664A (en) * 1979-05-14 1981-08-04 Medtronic, Inc. Implantable telemetry transmission system for analog and digital data
JPS5810066A (en) * 1981-07-10 1983-01-20 株式会社アドバンス Plaster structure for ion tofuorese
US4494950A (en) * 1982-01-19 1985-01-22 The Johns Hopkins University Plural module medication delivery system
US4639244A (en) * 1983-05-03 1987-01-27 Nabil I. Rizk Implantable electrophoretic pump for ionic drugs and associated methods
US5224928A (en) * 1983-08-18 1993-07-06 Drug Delivery Systems Inc. Mounting system for transdermal drug applicator
US4541431A (en) * 1984-09-20 1985-09-17 Telectronics Pty. Ltd. Use of telemetry coil to replace magnetically activated reed switch in implantable devices
US4585652A (en) * 1984-11-19 1986-04-29 Regents Of The University Of Minnesota Electrochemical controlled release drug delivery system
US4819657A (en) * 1985-04-12 1989-04-11 Kvm Engineering, Inc. Automatic allergy detection system
US4942883A (en) * 1987-09-29 1990-07-24 Newman Martin H Drug delivery device
US5108363A (en) * 1988-02-19 1992-04-28 Gensia Pharmaceuticals, Inc. Diagnosis, evaluation and treatment of coronary artery disease by exercise simulation using closed loop drug delivery of an exercise simulating agent beta agonist
US5011472A (en) * 1988-09-06 1991-04-30 Brown University Research Foundation Implantable delivery system for biological factors
US5006108A (en) * 1988-11-16 1991-04-09 Noven Pharmaceuticals, Inc. Apparatus for iontophoretic drug delivery
US4981141A (en) * 1989-02-15 1991-01-01 Jacob Segalowitz Wireless electrocardiographic monitoring system
US5047007A (en) * 1989-12-22 1991-09-10 Medtronic, Inc. Method and apparatus for pulsed iontophoretic drug delivery
US5036861A (en) * 1990-01-11 1991-08-06 Sembrowich Walter L Method and apparatus for non-invasively monitoring plasma glucose levels
DE4028125A1 (en) * 1990-01-17 1991-07-18 Klimke Markus Application plaster for regulated dosing of various pharmacons - uses electrical correct for percutaneous transport for local and systematic therapy
US5160316A (en) * 1990-09-10 1992-11-03 Henley Julian L Iontophoretic drug delivery apparatus
US5167626A (en) * 1990-10-02 1992-12-01 Glaxo Inc. Medical capsule device actuated by radio-frequency (RF) signal
US5170801A (en) * 1990-10-02 1992-12-15 Glaxo Inc. Medical capsule device actuated by radio-frequency (rf) signal
US5167625A (en) * 1990-10-09 1992-12-01 Sarcos Group Multiple vesicle implantable drug delivery system
US5059175A (en) * 1990-10-09 1991-10-22 University Of Utah Research Foundation Implantable drug delivery system with piston actuation
US5224927A (en) * 1990-11-01 1993-07-06 Robert Tapper Iontophoretic treatment system
US5254081A (en) * 1991-02-01 1993-10-19 Empi, Inc. Multiple site drug iontophoresis electronic device and method
US5279607A (en) * 1991-05-30 1994-01-18 The State University Of New York Telemetry capsule and process
EP0526166A2 (en) * 1991-07-29 1993-02-03 Albert L. Dessertine Patient compliance monitoring method and system
US5169384A (en) * 1991-08-16 1992-12-08 Bosniak Stephen L Apparatus for facilitating post-traumatic, post-surgical, and/or post-inflammatory healing of tissue
US5246418A (en) * 1991-12-17 1993-09-21 Becton Dickinson And Company Iontophresis system having features for reducing skin irritation
FR2687028B1 (en) * 1992-01-30 1994-04-29 I2M Innovation Materiel Medica DEVICE FOR REMOTE CONTROL OF THE INTENSITY DELIVERED BY A CURRENT GENERATOR WITH A HAND DIVE INTO A CONDUCTIVE LIQUID.
US5309919A (en) * 1992-03-02 1994-05-10 Siemens Pacesetter, Inc. Method and system for recording, reporting, and displaying the distribution of pacing events over time and for using same to optimize programming
FR2695566B1 (en) * 1992-09-16 1994-11-18 Michel Gebert Tissue electrophysiological stimulation device.
US5380271A (en) * 1992-09-24 1995-01-10 Alza Corporation Electrotransport agent delivery device and method

Also Published As

Publication number Publication date
DK0789603T3 (en) 2006-03-06
DE69534722T2 (en) 2006-08-31
JPH10507948A (en) 1998-08-04
AU3832695A (en) 1996-05-23
ATE314113T1 (en) 2006-01-15
MX9703227A (en) 1997-07-31
WO1996013302A1 (en) 1996-05-09
CA2198357C (en) 2005-08-16
DE69534722D1 (en) 2006-02-02
EP0789603A1 (en) 1997-08-20
EP0789603B1 (en) 2005-12-28
KR970706863A (en) 1997-12-01
ES2250975T3 (en) 2006-04-16
KR100382860B1 (en) 2003-08-06
AU691987B2 (en) 1998-05-28
US5551953A (en) 1996-09-03

Similar Documents

Publication Publication Date Title
CA2198357A1 (en) Electrotransport system with remote telemetry link
US5840047A (en) Sensor device for monitoring a prosthetic device
MX155664A (en) IMPROVEMENTS TO A PATIENT'S VITAL SIGN VERIFICATION SYSTEM
CA2202739A1 (en) Atrial defibrillation system having a portable communication device
EP1458122A3 (en) Polarized light communication device, transmitter, laser, polarized light communication device for physiological use, reflected light detector, and pulse wave detecting device
US5941905A (en) Public alarm for cochlear implant
GB9816011D0 (en) Monitoring treatment using implantable telemetric sensors
EP0880936A3 (en) Monitoring physical condition of a patient by telemetry
WO2003026734A3 (en) Method and apparatus for securing and/or identifying a link to a percutaneous probe
EP0834846A3 (en) Wireless hazard signalling system and method
AU9152382A (en) Remote transmission system
ES2070738A2 (en) System for detecting and remote signalling through radiofrequency a preset temperature in warm blood persons and animals
US5790050A (en) Method and apparatus for a signal translator
AU3086989A (en) Universal remote control transmitter with simplified device identification
GB2325519A (en) Physiological movement monitoring
IE860790L (en) Monitoring the parameters of a fluid using an infra-red transmitter and receiver
AU5489386A (en) Remote control device
WO1998034530A3 (en) Body sounds observation system
JPH0471090U (en)
DK1002496T3 (en) Method and device for remote monitoring of body functions
EP0247959A3 (en) Warning and/or alarm system for detecting the recuperation of vital constants in individuals diagnosed as clinically dead
JPH0337042A (en) Organism signal detecting telemeter
JPH01172805U (en)
EP0178613A3 (en) Permanent control system of the pneumatic pressure in the wheels of any automobile vehicle, aircraft or trailer
JPS6340065U (en)

Legal Events

Date Code Title Description
EEER Examination request
MKLA Lapsed