CA2198390A1 - Matrix for transdermal drug delivery - Google Patents
Matrix for transdermal drug deliveryInfo
- Publication number
- CA2198390A1 CA2198390A1 CA002198390A CA2198390A CA2198390A1 CA 2198390 A1 CA2198390 A1 CA 2198390A1 CA 002198390 A CA002198390 A CA 002198390A CA 2198390 A CA2198390 A CA 2198390A CA 2198390 A1 CA2198390 A1 CA 2198390A1
- Authority
- CA
- Canada
- Prior art keywords
- drug delivery
- transdermal drug
- matrix
- softener
- macromonomer
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Granted
Links
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/70—Web, sheet or filament bases ; Films; Fibres of the matrix type containing drug
- A61K9/7023—Transdermal patches and similar drug-containing composite devices, e.g. cataplasms
- A61K9/703—Transdermal patches and similar drug-containing composite devices, e.g. cataplasms characterised by shape or structure; Details concerning release liner or backing; Refillable patches; User-activated patches
- A61K9/7038—Transdermal patches of the drug-in-adhesive type, i.e. comprising drug in the skin-adhesive layer
- A61K9/7046—Transdermal patches of the drug-in-adhesive type, i.e. comprising drug in the skin-adhesive layer the adhesive comprising macromolecular compounds
- A61K9/7053—Transdermal patches of the drug-in-adhesive type, i.e. comprising drug in the skin-adhesive layer the adhesive comprising macromolecular compounds obtained by reactions only involving carbon to carbon unsaturated bonds, e.g. polyvinyl, polyisobutylene, polystyrene
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/70—Web, sheet or filament bases ; Films; Fibres of the matrix type containing drug
- A61K9/7023—Transdermal patches and similar drug-containing composite devices, e.g. cataplasms
- A61K9/703—Transdermal patches and similar drug-containing composite devices, e.g. cataplasms characterised by shape or structure; Details concerning release liner or backing; Refillable patches; User-activated patches
- A61K9/7038—Transdermal patches of the drug-in-adhesive type, i.e. comprising drug in the skin-adhesive layer
- A61K9/7046—Transdermal patches of the drug-in-adhesive type, i.e. comprising drug in the skin-adhesive layer the adhesive comprising macromolecular compounds
- A61K9/7053—Transdermal patches of the drug-in-adhesive type, i.e. comprising drug in the skin-adhesive layer the adhesive comprising macromolecular compounds obtained by reactions only involving carbon to carbon unsaturated bonds, e.g. polyvinyl, polyisobutylene, polystyrene
- A61K9/7061—Polyacrylates
-
- C—CHEMISTRY; METALLURGY
- C08—ORGANIC MACROMOLECULAR COMPOUNDS; THEIR PREPARATION OR CHEMICAL WORKING-UP; COMPOSITIONS BASED THEREON
- C08F—MACROMOLECULAR COMPOUNDS OBTAINED BY REACTIONS ONLY INVOLVING CARBON-TO-CARBON UNSATURATED BONDS
- C08F290/00—Macromolecular compounds obtained by polymerising monomers on to polymers modified by introduction of aliphatic unsaturated end or side groups
- C08F290/02—Macromolecular compounds obtained by polymerising monomers on to polymers modified by introduction of aliphatic unsaturated end or side groups on to polymers modified by introduction of unsaturated end groups
- C08F290/04—Polymers provided for in subclasses C08C or C08F
-
- C—CHEMISTRY; METALLURGY
- C09—DYES; PAINTS; POLISHES; NATURAL RESINS; ADHESIVES; COMPOSITIONS NOT OTHERWISE PROVIDED FOR; APPLICATIONS OF MATERIALS NOT OTHERWISE PROVIDED FOR
- C09J—ADHESIVES; NON-MECHANICAL ASPECTS OF ADHESIVE PROCESSES IN GENERAL; ADHESIVE PROCESSES NOT PROVIDED FOR ELSEWHERE; USE OF MATERIALS AS ADHESIVES
- C09J155/00—Adhesives based on homopolymers or copolymers, obtained by polymerisation reactions only involving carbon-to-carbon unsaturated bonds, not provided for in groups C09J123/00 - C09J153/00
- C09J155/005—Homopolymers or copolymers obtained by polymerisation of macromolecular compounds terminated by a carbon-to-carbon double bond
Abstract
A transdermal drug delivery device involving a macromonomer-containing acrylate or methacrylate copolymer, a softener, and a drug. Also a pressure sensitive skin adhesive involving a macromonomer containing acrylate or methacrylate copolymer and a softener.
Applications Claiming Priority (2)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
US30583394A | 1994-09-14 | 1994-09-14 | |
US08/305,833 | 1994-09-14 |
Publications (2)
Publication Number | Publication Date |
---|---|
CA2198390A1 true CA2198390A1 (en) | 1996-03-21 |
CA2198390C CA2198390C (en) | 2009-08-11 |
Family
ID=23182561
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
CA002198390A Expired - Fee Related CA2198390C (en) | 1994-09-14 | 1995-09-12 | Matrix for transdermal drug delivery |
Country Status (14)
Country | Link |
---|---|
US (2) | US7097853B1 (en) |
EP (1) | EP0781122B1 (en) |
JP (1) | JP4102901B2 (en) |
KR (1) | KR100382706B1 (en) |
AT (1) | ATE194281T1 (en) |
AU (1) | AU702593B2 (en) |
CA (1) | CA2198390C (en) |
DE (1) | DE69517816T2 (en) |
DK (1) | DK0781122T3 (en) |
ES (1) | ES2147858T3 (en) |
GR (1) | GR3033859T3 (en) |
NZ (1) | NZ293849A (en) |
PT (1) | PT781122E (en) |
WO (1) | WO1996008229A2 (en) |
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US5298258A (en) | 1989-12-28 | 1994-03-29 | Nitto Denko Corporation | Acrylic oily gel bioadhesive material and acrylic oily gel preparation |
US5032637A (en) | 1990-03-14 | 1991-07-16 | Adhesives Research Inc. | Water-inactivatable pressure sensitive adhesive |
JP2849937B2 (en) | 1990-04-18 | 1999-01-27 | 日東電工株式会社 | Medical patch |
CA2039586A1 (en) | 1990-05-02 | 1991-11-03 | Marian R. Appelt | Crosslinked pressure-sensitive adhesives tolerant of alcohol-based excipients used in transdermal delivery devices and method of preparing same |
US5143972A (en) | 1990-05-17 | 1992-09-01 | Minnesota Mining And Manufacturing Company | Pressure-sensitive adhesive composition |
DE4020144A1 (en) | 1990-06-25 | 1992-01-09 | Lohmann Therapie Syst Lts | Patches for topical or transdermal drug delivery - with adhesive layer contg. polyacrylate adhesive and film former |
JP2849950B2 (en) | 1990-11-30 | 1999-01-27 | 日東電工株式会社 | Transdermal formulation |
JPH04216886A (en) | 1990-12-17 | 1992-08-06 | Lintec Corp | Self-adhesive sheet resistant to blistering |
AU641580B2 (en) | 1991-02-28 | 1993-09-23 | National Starch And Chemical Investment Holding Corporation | Water vapor permeable pressure sensitive adhesive composition |
WO1993006184A1 (en) | 1991-09-23 | 1993-04-01 | Minnesota Mining And Manufacturing Company | PRESSURE SENSITIVE ADHESIVE COMPOSITION WHICH IS REPULPABLE UNDER ACIDIC pH CONDITIONS |
US5276079A (en) * | 1991-11-15 | 1994-01-04 | Minnesota Mining And Manufacturing Company | Pressure-sensitive poly(n-vinyl lactam) adhesive composition and method for producing and using same |
US5352516A (en) | 1992-01-31 | 1994-10-04 | Adhesives Research, Inc. | Water-inactivatable pressure sensitive adhesive |
US5302629A (en) * | 1992-05-15 | 1994-04-12 | Berejka Anthony J | Hydrophilic acrylic pressure sensitive adhesives |
US5264219A (en) | 1992-08-07 | 1993-11-23 | Minnesota Mining And Manufacturing Company | Transdermal drug delivery backing |
US5489624A (en) | 1992-12-01 | 1996-02-06 | Minnesota Mining And Manufacturing Company | Hydrophilic pressure sensitive adhesives |
SG49755A1 (en) | 1992-12-07 | 1998-06-15 | Minnesota Mining & Mfg | Adhesive for polycarbonate |
US5395907A (en) | 1993-11-29 | 1995-03-07 | Adhesive Research, Inc. | Water-soluble pressure sensitive adhesive |
US5508367A (en) | 1993-11-29 | 1996-04-16 | Adhesives Research, Inc. | Water-soluble pressure sensitive adhesive |
US5573778A (en) | 1995-03-17 | 1996-11-12 | Adhesives Research, Inc. | Drug flux enhancer-tolerant pressure sensitive adhesive composition |
US5614210A (en) | 1995-03-31 | 1997-03-25 | Minnesota Mining And Manufacturing Company | Transdermal device for the delivery of alfuzosin |
-
1995
- 1995-09-12 AT AT95933919T patent/ATE194281T1/en not_active IP Right Cessation
- 1995-09-12 PT PT95933919T patent/PT781122E/en unknown
- 1995-09-12 ES ES95933919T patent/ES2147858T3/en not_active Expired - Lifetime
- 1995-09-12 DE DE69517816T patent/DE69517816T2/en not_active Revoked
- 1995-09-12 KR KR1019970701693A patent/KR100382706B1/en not_active IP Right Cessation
- 1995-09-12 EP EP95933919A patent/EP0781122B1/en not_active Revoked
- 1995-09-12 NZ NZ293849A patent/NZ293849A/en not_active IP Right Cessation
- 1995-09-12 CA CA002198390A patent/CA2198390C/en not_active Expired - Fee Related
- 1995-09-12 AU AU36397/95A patent/AU702593B2/en not_active Ceased
- 1995-09-12 DK DK95933919T patent/DK0781122T3/en active
- 1995-09-12 JP JP51043296A patent/JP4102901B2/en not_active Expired - Fee Related
- 1995-09-12 WO PCT/US1995/012163 patent/WO1996008229A2/en not_active Application Discontinuation
-
1997
- 1997-11-12 US US08/968,519 patent/US7097853B1/en not_active Expired - Fee Related
-
2000
- 2000-07-06 GR GR20000401412T patent/GR3033859T3/en not_active IP Right Cessation
-
2005
- 2005-12-23 US US11/318,312 patent/US20060099242A1/en not_active Abandoned
Also Published As
Publication number | Publication date |
---|---|
DK0781122T3 (en) | 2000-10-30 |
AU3639795A (en) | 1996-03-29 |
US7097853B1 (en) | 2006-08-29 |
AU702593B2 (en) | 1999-02-25 |
NZ293849A (en) | 1998-10-28 |
US20060099242A1 (en) | 2006-05-11 |
JPH10508296A (en) | 1998-08-18 |
ATE194281T1 (en) | 2000-07-15 |
CA2198390C (en) | 2009-08-11 |
KR100382706B1 (en) | 2003-10-10 |
JP4102901B2 (en) | 2008-06-18 |
EP0781122A2 (en) | 1997-07-02 |
GR3033859T3 (en) | 2000-10-31 |
ES2147858T3 (en) | 2000-10-01 |
EP0781122B1 (en) | 2000-07-05 |
PT781122E (en) | 2000-11-30 |
WO1996008229A3 (en) | 1996-07-25 |
DE69517816D1 (en) | 2000-08-10 |
WO1996008229A2 (en) | 1996-03-21 |
DE69517816T2 (en) | 2000-12-28 |
KR970705974A (en) | 1997-11-03 |
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Legal Events
Date | Code | Title | Description |
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EEER | Examination request | ||
MKLA | Lapsed |