CA2210559A1 - Analytical system with means for detecting too small sample volumes - Google Patents

Analytical system with means for detecting too small sample volumes

Info

Publication number
CA2210559A1
CA2210559A1 CA002210559A CA2210559A CA2210559A1 CA 2210559 A1 CA2210559 A1 CA 2210559A1 CA 002210559 A CA002210559 A CA 002210559A CA 2210559 A CA2210559 A CA 2210559A CA 2210559 A1 CA2210559 A1 CA 2210559A1
Authority
CA
Canada
Prior art keywords
zone
evaluation
light
output signal
measured
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Granted
Application number
CA002210559A
Other languages
French (fr)
Other versions
CA2210559C (en
Inventor
Franz Bolduan
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Roche Diagnostics GmbH
Original Assignee
Boehringer Mannheim GmbH
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Priority claimed from DE19628562A external-priority patent/DE19628562A1/en
Priority claimed from DE19630160A external-priority patent/DE19630160A1/en
Application filed by Boehringer Mannheim GmbH filed Critical Boehringer Mannheim GmbH
Publication of CA2210559A1 publication Critical patent/CA2210559A1/en
Application granted granted Critical
Publication of CA2210559C publication Critical patent/CA2210559C/en
Anticipated expiration legal-status Critical
Expired - Lifetime legal-status Critical Current

Links

Classifications

    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N21/00—Investigating or analysing materials by the use of optical means, i.e. using sub-millimetre waves, infrared, visible or ultraviolet light
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N21/00—Investigating or analysing materials by the use of optical means, i.e. using sub-millimetre waves, infrared, visible or ultraviolet light
    • G01N21/84—Systems specially adapted for particular applications
    • G01N21/8483—Investigating reagent band
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N35/00—Automatic analysis not limited to methods or materials provided for in any single one of groups G01N1/00 - G01N33/00; Handling materials therefor
    • G01N35/00029—Automatic analysis not limited to methods or materials provided for in any single one of groups G01N1/00 - G01N33/00; Handling materials therefor provided with flat sample substrates, e.g. slides
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N35/00—Automatic analysis not limited to methods or materials provided for in any single one of groups G01N1/00 - G01N33/00; Handling materials therefor
    • G01N35/00584—Control arrangements for automatic analysers
    • G01N35/00594—Quality control, including calibration or testing of components of the analyser
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N35/00—Automatic analysis not limited to methods or materials provided for in any single one of groups G01N1/00 - G01N33/00; Handling materials therefor
    • G01N35/00584—Control arrangements for automatic analysers
    • G01N35/00594—Quality control, including calibration or testing of components of the analyser
    • G01N35/00603—Reinspection of samples
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N35/00—Automatic analysis not limited to methods or materials provided for in any single one of groups G01N1/00 - G01N33/00; Handling materials therefor
    • G01N35/00584—Control arrangements for automatic analysers
    • G01N35/00722—Communications; Identification
    • G01N2035/00891—Displaying information to the operator
    • G01N2035/009—Displaying information to the operator alarms, e.g. audible
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N35/00—Automatic analysis not limited to methods or materials provided for in any single one of groups G01N1/00 - G01N33/00; Handling materials therefor
    • G01N35/10—Devices for transferring samples or any liquids to, in, or from, the analysis apparatus, e.g. suction devices, injection devices
    • G01N35/1009—Characterised by arrangements for controlling the aspiration or dispense of liquids
    • G01N35/1016—Control of the volume dispensed or introduced

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • General Physics & Mathematics (AREA)
  • Pathology (AREA)
  • Chemical & Material Sciences (AREA)
  • Analytical Chemistry (AREA)
  • Biochemistry (AREA)
  • Immunology (AREA)
  • Physics & Mathematics (AREA)
  • Engineering & Computer Science (AREA)
  • Quality & Reliability (AREA)
  • Molecular Biology (AREA)
  • Investigating Or Analysing Materials By Optical Means (AREA)
  • Investigating Or Analysing Biological Materials (AREA)
  • Investigating Or Analysing Materials By The Use Of Chemical Reactions (AREA)
  • Investigating Or Analyzing Non-Biological Materials By The Use Of Chemical Means (AREA)
  • Automatic Analysis And Handling Materials Therefor (AREA)

Abstract

Analytical system for evaluating test elements having means of determining whether a sufficient amount of sample liquid was evenly applied to an application zone comprising in a first embodiment of the invention at least two sources of light which illuminate separate or at least not fully overlapping areas of the application zone or the evaluation zone of the test strip, a control unit with which the light sources, of which there at least two, can be independently activated, at least one sensor which detects light reflected by the evaluation zone or transmitted by the evaluation zone and supplies an output signal proportional to the intensity of light as well as an evaluation unit which receives a first output signal from the sensor and converts it into a first measured value when the first of the light sources is activated, receives a second output signal from the sensor and converts it into a second measured value when the second of the light sources, is activated and compares the measured values and determines whether the deviation of the first value measured from the second value measured is sufficiently small. In a second embodiment of an analytical system according to the invention, at least one light source is used to illuminate the sample application zone or the evaluation zone of a test element and at least two sensors detect light reflected or transmitted by the evaluation zone, the output signal of the sensors being converted into measured values by the evaluation unit which determines whether the deviation of the measured values is sufficiently small.
CA002210559A 1996-07-16 1997-07-15 Analytical system with means for detecting too small sample volumes Expired - Lifetime CA2210559C (en)

Applications Claiming Priority (4)

Application Number Priority Date Filing Date Title
DE19628562.3 1996-07-16
DE19628562A DE19628562A1 (en) 1996-07-16 1996-07-16 Optical system evaluating quality of fluid distribution onto test piece, e.g. medical test strip
DE19630160A DE19630160A1 (en) 1996-07-26 1996-07-26 Optical system evaluating quality of fluid distribution onto test piece, e.g. medical test strip
DE19630160.2 1996-07-26

Publications (2)

Publication Number Publication Date
CA2210559A1 true CA2210559A1 (en) 1998-01-16
CA2210559C CA2210559C (en) 2001-12-18

Family

ID=26027543

Family Applications (1)

Application Number Title Priority Date Filing Date
CA002210559A Expired - Lifetime CA2210559C (en) 1996-07-16 1997-07-15 Analytical system with means for detecting too small sample volumes

Country Status (8)

Country Link
US (1) US6055060A (en)
EP (1) EP0819943A3 (en)
JP (1) JP3455654B2 (en)
KR (1) KR100219252B1 (en)
CN (1) CN1103051C (en)
AU (1) AU702209B2 (en)
CA (1) CA2210559C (en)
IL (1) IL121279A (en)

Cited By (4)

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US7521260B2 (en) 2005-04-22 2009-04-21 Alverix, Inc. Assay test strips and reading same
US7521259B2 (en) 2004-04-01 2009-04-21 Alverix, Inc. Assay test strips with multiple labels and reading same
US9891217B2 (en) 2005-04-22 2018-02-13 Alverix, Inc. Assay test strips with multiple labels and reading same
US10016134B2 (en) 2001-08-13 2018-07-10 Novo Nordisk A/S Portable device and method of communicating medical data information

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US10016134B2 (en) 2001-08-13 2018-07-10 Novo Nordisk A/S Portable device and method of communicating medical data information
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US10753931B2 (en) 2005-04-22 2020-08-25 Alverix, Inc. Assay test strips with multiple labels and reading same
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Also Published As

Publication number Publication date
JP3455654B2 (en) 2003-10-14
CA2210559C (en) 2001-12-18
CN1103051C (en) 2003-03-12
CN1174996A (en) 1998-03-04
JPH1073535A (en) 1998-03-17
KR980010410A (en) 1998-04-30
EP0819943A3 (en) 1998-09-16
EP0819943A2 (en) 1998-01-21
US6055060A (en) 2000-04-25
IL121279A (en) 2001-05-20
AU702209B2 (en) 1999-02-18
KR100219252B1 (en) 1999-09-01
IL121279A0 (en) 1998-01-04
AU2855797A (en) 1998-01-29

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