CA2217711A1 - Electrotransport delivery with voltage boosting circuit - Google Patents
Electrotransport delivery with voltage boosting circuitInfo
- Publication number
- CA2217711A1 CA2217711A1 CA002217711A CA2217711A CA2217711A1 CA 2217711 A1 CA2217711 A1 CA 2217711A1 CA 002217711 A CA002217711 A CA 002217711A CA 2217711 A CA2217711 A CA 2217711A CA 2217711 A1 CA2217711 A1 CA 2217711A1
- Authority
- CA
- Canada
- Prior art keywords
- boosting circuit
- voltage boosting
- electrotransport delivery
- voltage
- therapeutic
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Granted
Links
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61N—ELECTROTHERAPY; MAGNETOTHERAPY; RADIATION THERAPY; ULTRASOUND THERAPY
- A61N1/00—Electrotherapy; Circuits therefor
- A61N1/02—Details
- A61N1/04—Electrodes
- A61N1/0404—Electrodes for external use
- A61N1/0408—Use-related aspects
- A61N1/0428—Specially adapted for iontophoresis, e.g. AC, DC or including drug reservoirs
- A61N1/0432—Anode and cathode
- A61N1/044—Shape of the electrode
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61N—ELECTROTHERAPY; MAGNETOTHERAPY; RADIATION THERAPY; ULTRASOUND THERAPY
- A61N1/00—Electrotherapy; Circuits therefor
- A61N1/18—Applying electric currents by contact electrodes
- A61N1/20—Applying electric currents by contact electrodes continuous direct currents
- A61N1/30—Apparatus for iontophoresis, i.e. transfer of media in ionic state by an electromotoric force into the body, or cataphoresis
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61N—ELECTROTHERAPY; MAGNETOTHERAPY; RADIATION THERAPY; ULTRASOUND THERAPY
- A61N1/00—Electrotherapy; Circuits therefor
- A61N1/18—Applying electric currents by contact electrodes
- A61N1/32—Applying electric currents by contact electrodes alternating or intermittent currents
- A61N1/325—Applying electric currents by contact electrodes alternating or intermittent currents for iontophoresis, i.e. transfer of media in ionic state by an electromotoric force into the body
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61N—ELECTROTHERAPY; MAGNETOTHERAPY; RADIATION THERAPY; ULTRASOUND THERAPY
- A61N1/00—Electrotherapy; Circuits therefor
- A61N1/02—Details
- A61N1/04—Electrodes
- A61N1/0404—Electrodes for external use
- A61N1/0408—Use-related aspects
- A61N1/0428—Specially adapted for iontophoresis, e.g. AC, DC or including drug reservoirs
- A61N1/0448—Drug reservoir
Abstract
An electrotransport device (10) for delivering therapeutic agents includes an adjustable voltage boost multiple controller (100, 200) for boosting the voltage from a power source (102, 202) to a working voltage V w having a value just sufficient to provide the desired therapeutic current level I1 through the electrodes (108, 112), at least one of which contains the therapeutic agent to be delivered.
Therapeutic agents to be delivered according to the present invention include fentanyl and other agents.
Therapeutic agents to be delivered according to the present invention include fentanyl and other agents.
Applications Claiming Priority (3)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
US46032295A | 1995-06-02 | 1995-06-02 | |
US08/460,322 | 1995-06-02 | ||
PCT/US1996/008258 WO1996038199A1 (en) | 1995-06-02 | 1996-05-30 | An electrotransport delivery device with voltage boosting circuit |
Publications (2)
Publication Number | Publication Date |
---|---|
CA2217711A1 true CA2217711A1 (en) | 1996-12-05 |
CA2217711C CA2217711C (en) | 2009-05-19 |
Family
ID=23828237
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
CA002217711A Expired - Fee Related CA2217711C (en) | 1995-06-02 | 1996-05-30 | Electrotransport delivery with voltage boosting circuit |
Country Status (18)
Country | Link |
---|---|
US (4) | US6035234A (en) |
EP (1) | EP0830176B1 (en) |
JP (1) | JPH11511677A (en) |
KR (1) | KR100454667B1 (en) |
CN (1) | CN1099300C (en) |
AT (2) | AT408616B (en) |
AU (1) | AU700477B2 (en) |
BE (1) | BE1009518A5 (en) |
CA (1) | CA2217711C (en) |
CH (1) | CH690818A5 (en) |
DE (2) | DE19681422T1 (en) |
DK (1) | DK0830176T3 (en) |
ES (1) | ES2184867T3 (en) |
IE (1) | IE960312A1 (en) |
MX (1) | MX9709365A (en) |
PT (1) | PT830176E (en) |
SE (1) | SE520344C2 (en) |
WO (1) | WO1996038199A1 (en) |
Families Citing this family (72)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
IE960312A1 (en) * | 1995-06-02 | 1996-12-11 | Alza Corp | An electrotransport delivery device with voltage boosting¹circuit |
US5983133A (en) * | 1997-09-29 | 1999-11-09 | Becton, Dickinson And Company | Iontophoresis system with voltage step-up circuit |
JP2002508228A (en) * | 1997-12-16 | 2002-03-19 | アルザ・コーポレーション | Regulator with artificial load to maintain regulated dosing |
EP1183068A4 (en) * | 1999-05-10 | 2008-12-17 | Gentronics Inc | Method of electroporation-enhanced delivery of active agents |
US7171264B1 (en) * | 1999-05-10 | 2007-01-30 | Genetronics, Inc. | Intradermal delivery of active agents by needle-free injection and electroporation |
US6385488B1 (en) | 1999-05-20 | 2002-05-07 | Vyteris, Inc. | Circuits for increasing the reliability of an iontophoretic system |
JP2001286569A (en) * | 2000-04-05 | 2001-10-16 | Polytronics Ltd | Endermism device |
US6453195B1 (en) | 2001-03-19 | 2002-09-17 | Medtronic, Inc. | Closed loop drug delivery system and remote management thereof |
DE10141650C1 (en) | 2001-08-24 | 2002-11-28 | Lohmann Therapie Syst Lts | Safe transdermal therapeutic system for administration of fentanyl or analogous analgesics, having matrix layer of carboxy group-free polyacrylate adhesive providing high permeation rate |
US20040098065A1 (en) * | 2002-11-19 | 2004-05-20 | Alliance Health Products, Llc | Transcutaneous nerve and muscle stimulator and method of using the same |
JP2006334164A (en) * | 2005-06-02 | 2006-12-14 | Transcutaneous Technologies Inc | Iontophoresis apparatus and method for controlling the same |
JP2007000342A (en) * | 2005-06-23 | 2007-01-11 | Transcutaneous Technologies Inc | Iontophoresis device for controlling quantity and time of dosing a plurality of medicaments |
JPWO2007010900A1 (en) * | 2005-07-15 | 2009-01-29 | Tti・エルビュー株式会社 | Patch for percutaneous absorption with ion position display function and iontophoresis device |
ITMI20051356A1 (en) | 2005-07-15 | 2007-01-16 | Getters Spa | GETTER DEVICE FOR ACTIVE SYSTEMS FOR TRANSDERMIC RELEASE OF DRUGS |
JP2007037868A (en) * | 2005-08-05 | 2007-02-15 | Transcutaneous Technologies Inc | Transdermal administration device and its controlling method |
US20070088331A1 (en) * | 2005-08-18 | 2007-04-19 | Transcutaneous Technologies Inc. | Method and apparatus for managing active agent usage, and active agent injecting device |
WO2007026671A1 (en) * | 2005-08-29 | 2007-03-08 | Transcu Ltd. | Iontophoresis device for selecting medicine to be administrated according to information from sensor |
WO2007031973A2 (en) * | 2005-09-15 | 2007-03-22 | Visible Assets, Inc. | Active low frequency radio tag and patch drug delivery system |
RU2008114490A (en) * | 2005-09-15 | 2009-10-20 | ТиТиАй ЭЛЛЕБО, ИНК. (JP) | STEM TYPE IONTOPHORESIS DEVICE |
US20070071807A1 (en) * | 2005-09-28 | 2007-03-29 | Hidero Akiyama | Capsule-type drug-releasing device and capsule-type drug-releasing device system |
WO2007041115A1 (en) * | 2005-09-30 | 2007-04-12 | Tti Ellebeau Inc. | Method and system to detect malfunctions in an iontophoresis device that delivers active agents to biological interfaces |
US20090299265A1 (en) * | 2005-09-30 | 2009-12-03 | Tti Ellebeau, Inc. | Electrode Assembly for Iontophoresis Having Shape-Memory Separator and Iontophoresis Device Using the Same |
US20070135754A1 (en) * | 2005-09-30 | 2007-06-14 | Hidero Akiyama | Electrode assembly for iontophoresis for administering active agent enclosed in nanoparticle and iontophoresis device using the same |
EP1928539A1 (en) * | 2005-09-30 | 2008-06-11 | Tti Ellebeau, Inc. | Functionalized microneedles transdermal drug delivery systems, devices, and methods |
US20070078445A1 (en) * | 2005-09-30 | 2007-04-05 | Curt Malloy | Synchronization apparatus and method for iontophoresis device to deliver active agents to biological interfaces |
US20070197955A1 (en) * | 2005-10-12 | 2007-08-23 | Transcutaneous Technologies Inc. | Mucous membrane adhesion-type iontophoresis device |
WO2007079189A2 (en) * | 2005-12-30 | 2007-07-12 | Tti Ellebeau, Inc. | System and method for remote based control of an iontophoresis device |
CA2935569A1 (en) * | 2006-04-13 | 2007-10-25 | Teva Pharmaceuticals International Gmbh | Transdermal methods and systems for the delivery of anti-migraine compounds |
WO2007132470A2 (en) * | 2006-05-17 | 2007-11-22 | Power Paper Ltd | Constant current treatment device |
WO2008004204A1 (en) * | 2006-07-06 | 2008-01-10 | University Of Limerick | An electrical stimulation device for nerves or muscles |
US20080077076A1 (en) * | 2006-08-29 | 2008-03-27 | Transcutaneous Technologies Inc. | Iontophoresis device and method for operation with a usb (universal serial bus) power source |
EP2059298A2 (en) * | 2006-09-05 | 2009-05-20 | Tti Ellebeau, Inc. | Transdermal drug delivery systems, devices, and methods using inductive power supplies |
US8728059B2 (en) * | 2006-09-29 | 2014-05-20 | Covidien Lp | System and method for assuring validity of monitoring parameter in combination with a therapeutic device |
BRPI0719353A2 (en) | 2006-12-01 | 2014-01-07 | Titi Ellebeau Inc | SYSTEMS, DEVICES AND METHODS FOR ENERGIZATION AND / OR CONTROL DEVICES, FOR EXAMPLE, TRANSDERMIC DISTRIBUTION DEVICES |
US20080177219A1 (en) * | 2007-01-23 | 2008-07-24 | Joshi Ashok V | Method for Iontophoretic Fluid Delivery |
US20080188791A1 (en) * | 2007-02-02 | 2008-08-07 | Difiore Attilio E | Active iontophoresis delivery system |
US8095213B1 (en) * | 2007-05-31 | 2012-01-10 | Purdue Pharma L.P. | Transdermal patch |
US7853320B1 (en) | 2007-05-31 | 2010-12-14 | Purdue Pharma L.P. | Transdermal device having mechanical assist for porator-to-skin contact |
US8197844B2 (en) * | 2007-06-08 | 2012-06-12 | Activatek, Inc. | Active electrode for transdermal medicament administration |
US8047399B1 (en) | 2007-07-05 | 2011-11-01 | Purdue Pharma L.P. | Dispenser for transdermal devices |
US20090043244A1 (en) * | 2007-08-08 | 2009-02-12 | Inan Omer T | Electrotransport Drug Delivery Device Adaptable to Skin Resistance Change |
US8862223B2 (en) | 2008-01-18 | 2014-10-14 | Activatek, Inc. | Active transdermal medicament patch and circuit board for same |
US8366600B2 (en) * | 2008-06-19 | 2013-02-05 | Nupathe Inc. | Polyamine enhanced formulations for triptan compound iontophoresis |
US8155737B2 (en) * | 2008-06-19 | 2012-04-10 | Nupathe, Inc. | Pharmacokinetics of iontophoretic sumatriptan administration |
US20100082219A1 (en) * | 2008-09-30 | 2010-04-01 | Gm Global Technology Operations, Inc. | Engine Using Glow Plug Resistance For Estimating Combustion Temperature |
ES2612830T3 (en) * | 2008-12-30 | 2017-05-18 | Teva Pharmaceuticals International Gmbh | Electronic control of drug delivery system |
US8961492B2 (en) | 2009-02-12 | 2015-02-24 | Incube Labs, Llc | System and method for controlling the iontophoretic delivery of therapeutic agents based on user inhalation |
US9008765B2 (en) | 2009-02-12 | 2015-04-14 | Incube Labs, Llc | System and method for biphasic transdermal iontophoretic delivery of therapeutic agents for the control of addictive cravings |
US8190252B2 (en) | 2009-02-12 | 2012-05-29 | Incube Labs, Llc | Iontophoretic system for transdermal delivery of active agents for therapeutic and medicinal purposes |
US8903485B2 (en) | 2009-08-06 | 2014-12-02 | Incube Labs, Llc | Patch and patch assembly for iontophoretic transdermal delivery of active agents for therapeutic and medicinal purposes |
CN102573489A (en) | 2009-08-10 | 2012-07-11 | 纽帕特公司 | Methods for iontophoretically treating nausea and migraine |
WO2011046927A1 (en) * | 2009-10-13 | 2011-04-21 | Nupathe,Inc. | Transdermal methods and systems for the delivery of rizatriptan |
US8685038B2 (en) | 2009-12-07 | 2014-04-01 | Incube Labs, Llc | Iontophoretic apparatus and method for marking of the skin |
WO2011100376A2 (en) | 2010-02-10 | 2011-08-18 | Incube Labs, Llc | Methods and architecture for power optimization of iontophoretic transdermal drug delivery |
CN101829407B (en) * | 2010-05-14 | 2012-03-28 | 武汉海纳川科技有限公司 | Semiconductor laser blood oxygen therapeutic apparatus |
KR200457838Y1 (en) | 2010-05-27 | 2012-01-05 | 주식회사 가람아이앤씨 | Portable Massager using an analog based step-up transformer circuit of 1.5V battery |
CN101869739A (en) * | 2010-07-20 | 2010-10-27 | 段峰 | Self-adaptive control skin surface electrical stimulation device and method |
CA2817824A1 (en) | 2010-11-23 | 2012-05-31 | Nupathe, Inc. | User-activated self-contained co-packaged iontophoretic drug delivery system |
EP3626304A1 (en) | 2011-03-24 | 2020-03-25 | Incube Labs, Llc | System and method for biphasic transdermal iontophoretic delivery of therapeutic agents |
US8428708B1 (en) | 2012-05-21 | 2013-04-23 | Incline Therapeutics, Inc. | Self-test for analgesic product |
US8428709B1 (en) * | 2012-06-11 | 2013-04-23 | Incline Therapeutics, Inc. | Current control for electrotransport drug delivery |
US8301238B2 (en) | 2011-03-31 | 2012-10-30 | Incline Therapeutics, Inc. | Two-part electrotransport device |
US8781571B2 (en) | 2011-03-31 | 2014-07-15 | Incline Therapeutics, Inc. | Switch validation circuit and method |
US9731121B2 (en) | 2011-03-31 | 2017-08-15 | Incline Therapeutics, Inc. | Switch validation circuit and method |
GB201414695D0 (en) * | 2014-08-19 | 2014-10-01 | Femeda Ltd | Electrostimulation related devices and methods |
US10463854B2 (en) | 2015-02-24 | 2019-11-05 | Elira, Inc. | Systems and methods for managing symptoms associated with dysmenorrhea using an electro-dermal patch |
JP2018050879A (en) * | 2016-09-28 | 2018-04-05 | 株式会社大島製作所 | Electric stimulation device |
USD821593S1 (en) * | 2016-11-23 | 2018-06-26 | Elira, Inc. | Electro-dermal patch for use as a medical device |
CN114081475A (en) * | 2017-11-28 | 2022-02-25 | 韦斯特伯格控股公司 | Training auxiliary stimulator and method for providing electrical stimulation |
US11251635B2 (en) | 2017-12-19 | 2022-02-15 | Welch Allyn, Inc. | Vital signs monitor with a removable and dischargable battery |
CN109564457B (en) * | 2018-10-30 | 2022-08-02 | 深圳市锐明技术股份有限公司 | Power-off protection circuit, device and system for vehicle-mounted equipment |
US20230195149A1 (en) * | 2021-12-17 | 2023-06-22 | ONiO AS | Power saving in an embedded system |
Family Cites Families (81)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
FR558409A (en) * | 1922-11-08 | 1923-08-27 | water level square | |
US3618601A (en) * | 1969-10-16 | 1971-11-09 | Thatcher W Richardson | Iontophoresis unit |
US3991755A (en) * | 1973-07-27 | 1976-11-16 | Medicon, Inc. | Iontophoresis apparatus for applying local anesthetics |
US4019510A (en) * | 1975-02-10 | 1977-04-26 | Sybron Corporation | Therapeutic method of using low intensity direct current generator with polarity reversal |
US4141359A (en) * | 1976-08-16 | 1979-02-27 | University Of Utah | Epidermal iontophoresis device |
JPS5347192A (en) * | 1976-10-13 | 1978-04-27 | Matsushita Electric Ind Co Ltd | Device for introducing fluorine ion to tooth |
US4301794A (en) * | 1978-10-18 | 1981-11-24 | Robert Tapper | Method for iontophoretic treatment |
US4340047A (en) * | 1978-10-18 | 1982-07-20 | Robert Tapper | Iontophoretic treatment apparatus |
US4250878A (en) * | 1978-11-22 | 1981-02-17 | Motion Control, Inc. | Non-invasive chemical species delivery apparatus and method |
JPS56501274A (en) * | 1979-10-10 | 1981-09-10 | ||
US4292968A (en) * | 1979-11-26 | 1981-10-06 | Sybron Corporation | Electric supply for ion therapy |
US4383529A (en) * | 1980-11-03 | 1983-05-17 | Wescor, Inc. | Iontophoretic electrode device, method and gel insert |
US4406658A (en) * | 1981-03-06 | 1983-09-27 | Medtronic, Inc. | Iontophoretic device with reversible polarity |
DE3137384A1 (en) * | 1981-09-19 | 1983-04-07 | Bayer Ag, 5090 Leverkusen | FLOCKABLE STABILITY MIXED-PHASE PIGMENTS WITH RUTILE STRUCTURE, METHOD FOR THEIR PRODUCTION AND THEIR USE |
US4457748A (en) * | 1982-01-11 | 1984-07-03 | Medtronic, Inc. | Non-invasive diagnosis method |
US4456012A (en) * | 1982-02-22 | 1984-06-26 | Medtronic, Inc. | Iontophoretic and electrical tissue stimulation device |
EP0092015A1 (en) * | 1982-04-16 | 1983-10-26 | Roland Brodard | Ionizing device |
US4808152A (en) * | 1983-08-18 | 1989-02-28 | Drug Delivery Systems Inc. | System and method for controlling rate of electrokinetic delivery of a drug |
US5224928A (en) * | 1983-08-18 | 1993-07-06 | Drug Delivery Systems Inc. | Mounting system for transdermal drug applicator |
CA1262564A (en) * | 1983-09-01 | 1989-10-31 | Minoru Sasaki | Iontophoresis device |
EP0308572B1 (en) * | 1983-09-01 | 1995-11-08 | Hisamitsu Pharmaceutical Co., Inc. | An iontophoresis device |
US4855243A (en) * | 1983-09-26 | 1989-08-08 | H.S.G. Venture (A Joint Venture Partnership) | Neurological and biological molecular electro-optical devices and methods |
JPS6222662A (en) * | 1985-07-19 | 1987-01-30 | 林原 健 | Ion introducing electronic treatment device |
JPS62139672A (en) * | 1985-12-14 | 1987-06-23 | 林原 健 | Remedy device for positive and negative iontophoresis |
IE60941B1 (en) * | 1986-07-10 | 1994-09-07 | Elan Transdermal Ltd | Transdermal drug delivery device |
US5250022A (en) * | 1990-09-25 | 1993-10-05 | Rutgers, The State University Of New Jersey | Iontotherapeutic devices, reservoir electrode devices therefore, process and unit dose |
US5042975A (en) * | 1986-07-25 | 1991-08-27 | Rutgers, The State University Of New Jersey | Iontotherapeutic device and process and iontotherapeutic unit dose |
US4725263A (en) * | 1986-07-31 | 1988-02-16 | Medtronic, Inc. | Programmable constant current source transdermal drug delivery system |
JPS63145669A (en) * | 1986-10-11 | 1988-06-17 | 林原 健 | Switch for positive and negative iontophorese |
US4786277A (en) * | 1986-11-21 | 1988-11-22 | Trustees Of Boston University | Electrodes, electrode assemblies, methods, and systems for tissue stimulation |
US4822334A (en) * | 1986-12-04 | 1989-04-18 | Robert Tapper | Electrical dosimetry control system |
FR2607708B3 (en) * | 1986-12-05 | 1989-02-24 | Bontemps Raymond | DEVICE FOR SUBCUTANEOUS TRANSFER OF MEDICINAL SUBSTANCES |
US4878892A (en) * | 1987-02-10 | 1989-11-07 | Drug Delivery Systems Inc. | Electrolytic transdermal delivery of polypeptides |
US4931046A (en) * | 1987-05-15 | 1990-06-05 | Newman Martin H | Iontophoresis drug delivery system |
US5013293A (en) * | 1987-05-28 | 1991-05-07 | Drug Delivery Systems Inc. | Pulsating transdermal drug delivery system |
US5312325A (en) * | 1987-05-28 | 1994-05-17 | Drug Delivery Systems Inc | Pulsating transdermal drug delivery system |
US4866442A (en) * | 1987-06-01 | 1989-09-12 | Steim Joseph M | Analog to digital converter employing delta-sigma modulation |
US4764168A (en) * | 1987-08-28 | 1988-08-16 | Suh Ku W | Tympanic membrane implant |
US4942883A (en) * | 1987-09-29 | 1990-07-24 | Newman Martin H | Drug delivery device |
US4997418A (en) * | 1988-04-21 | 1991-03-05 | C. P. Chambers | Epidermal iontophoresis device |
GB2219210A (en) * | 1988-05-31 | 1989-12-06 | S G Daniel | Apparatus for modulating electro-dynamic fields associated with living tissue |
US4927408A (en) | 1988-10-03 | 1990-05-22 | Alza Corporation | Electrotransport transdermal system |
US5006108A (en) * | 1988-11-16 | 1991-04-09 | Noven Pharmaceuticals, Inc. | Apparatus for iontophoretic drug delivery |
US5135478A (en) * | 1989-05-10 | 1992-08-04 | Drug Delivery Systems Inc. | Multi-signal electrical transdermal drug applicator |
CA2071321C (en) * | 1989-05-10 | 2000-12-12 | Dan Sibalis | Multi-signal electrical transdermal drug applicator |
JPH0366384A (en) * | 1989-08-04 | 1991-03-22 | Senjiyu Seiyaku Kk | System for controlling release of physiologically active material |
DE59004707D1 (en) * | 1989-10-12 | 1994-03-31 | Siemens Ag | FILTER CONNECTOR. |
ES2095929T3 (en) * | 1989-10-23 | 1997-03-01 | Theratech Inc | IONTOPHORETIC DEVICE USING A REGIME REGULATOR. |
IT1244030B (en) * | 1989-12-21 | 1994-06-28 | Elan Corp Plc | TWO-PART DEVICE FOR THE CONTROLLED ADMINISTRATION OF AN INGREDIENT |
US5047007A (en) * | 1989-12-22 | 1991-09-10 | Medtronic, Inc. | Method and apparatus for pulsed iontophoretic drug delivery |
DE4028125A1 (en) * | 1990-01-17 | 1991-07-18 | Klimke Markus | Application plaster for regulated dosing of various pharmacons - uses electrical correct for percutaneous transport for local and systematic therapy |
JPH05506165A (en) * | 1990-03-30 | 1993-09-16 | アルザ・コーポレーション | Delivery device for iontophoresis |
WO1991015261A1 (en) * | 1990-03-30 | 1991-10-17 | Medtronic, Inc. | Activity controlled electrotransport drug delivery device |
US5213568A (en) * | 1990-03-30 | 1993-05-25 | Medtronic Inc. | Activity controlled electrotransport drug delivery device |
US5207752A (en) * | 1990-03-30 | 1993-05-04 | Alza Corporation | Iontophoretic drug delivery system with two-stage delivery profile |
CA2081896A1 (en) * | 1990-06-15 | 1991-12-16 | James E. Shapland | Drug delivery apparatus and method |
US5160316A (en) * | 1990-09-10 | 1992-11-03 | Henley Julian L | Iontophoretic drug delivery apparatus |
US5224927A (en) * | 1990-11-01 | 1993-07-06 | Robert Tapper | Iontophoretic treatment system |
US5254081A (en) * | 1991-02-01 | 1993-10-19 | Empi, Inc. | Multiple site drug iontophoresis electronic device and method |
US5169384A (en) * | 1991-08-16 | 1992-12-08 | Bosniak Stephen L | Apparatus for facilitating post-traumatic, post-surgical, and/or post-inflammatory healing of tissue |
EP0604504A4 (en) * | 1991-08-26 | 1995-05-17 | Univ Rutgers | Iontotherapeutic device and process. |
EP0615461B1 (en) * | 1991-12-03 | 1996-09-25 | Alza Corporation | Iontophoretic delivery device and power supply therefor |
US5256137A (en) * | 1992-03-10 | 1993-10-26 | Becton Dickinson And Company | Biphasic power source for use in an iontophoretic drug delivery system |
US5246418A (en) * | 1991-12-17 | 1993-09-21 | Becton Dickinson And Company | Iontophresis system having features for reducing skin irritation |
CA2084734C (en) * | 1991-12-17 | 1998-12-01 | John L. Haynes | Iontophoresis system having features for reducing skin irritation |
US5499967A (en) * | 1992-02-27 | 1996-03-19 | Societe Anonyme Dite: Laboratoires D'hygiene Societe Anonyme Dite: Et De Dietetique (L.H.D.) | Transdermal drug delivery device with waveshape generator |
FR2688106B1 (en) * | 1992-02-27 | 1994-09-09 | Lhd Lab Hygiene Dietetique | DEVICE FOR GENERATING AN PREDETERMINED WAVEFORM ELECTRIC VOLTAGE, IONOPHORETIC APPARATUS FOR TRANSDERMAL DELIVERY OF MEDICAMENTS. |
GB2265088B (en) | 1992-03-10 | 1996-02-07 | Kyosti Eero Antero Kontturi | Electrochemical device for drug delivery |
US5189307A (en) * | 1992-03-13 | 1993-02-23 | Empi, Inc. | Isolated current mirror with optical insulator generating feedback signal |
US5306235A (en) * | 1992-09-30 | 1994-04-26 | Becton Dickinson And Company | Failsafe iontophoresis drug delivery system |
US5533971A (en) | 1993-09-03 | 1996-07-09 | Alza Corporation | Reduction of skin irritation during electrotransport |
US5540654A (en) | 1994-09-02 | 1996-07-30 | North Carolina State University | Iontophoretic electrode |
US5697896A (en) | 1994-12-08 | 1997-12-16 | Alza Corporation | Electrotransport delivery device |
US5879322A (en) | 1995-03-24 | 1999-03-09 | Alza Corporation | Self-contained transdermal drug delivery device |
IE960312A1 (en) * | 1995-06-02 | 1996-12-11 | Alza Corp | An electrotransport delivery device with voltage boosting¹circuit |
CA2218369C (en) | 1995-06-05 | 2010-02-09 | Alza Corporation | Transdermal electrotransport delivery of fentanyl and sufentanil |
US6167301A (en) * | 1995-08-29 | 2000-12-26 | Flower; Ronald J. | Iontophoretic drug delivery device having high-efficiency DC-to-DC energy conversion circuit |
DE69633733T2 (en) | 1995-08-31 | 2006-02-02 | Hisamitsu Pharmaceutical Co., Inc., Tosu | IONTOPHORETIC DEVICE AND CORRESPONDING METHOD FOR CONTROLLING THE ELECTRICITY |
FR2755842B1 (en) * | 1996-11-19 | 1999-04-23 | Lhd Lab Hygiene Dietetique | METHOD FOR MEASURING THE SKIN RESISTANCE OF A PATIENT SUBJECT TO A TRANSDERMAL ADMINISTRATION OF MEDICAMENT |
JP2002508228A (en) | 1997-12-16 | 2002-03-19 | アルザ・コーポレーション | Regulator with artificial load to maintain regulated dosing |
JP2001286569A (en) * | 2000-04-05 | 2001-10-16 | Polytronics Ltd | Endermism device |
-
1996
- 1996-04-24 IE IE960312A patent/IE960312A1/en not_active IP Right Cessation
- 1996-04-25 BE BE9600363A patent/BE1009518A5/en not_active IP Right Cessation
- 1996-05-30 ES ES96916910T patent/ES2184867T3/en not_active Expired - Lifetime
- 1996-05-30 DE DE19681422T patent/DE19681422T1/en not_active Withdrawn
- 1996-05-30 WO PCT/US1996/008258 patent/WO1996038199A1/en active IP Right Grant
- 1996-05-30 AT AT0903496A patent/AT408616B/en not_active IP Right Cessation
- 1996-05-30 AU AU59630/96A patent/AU700477B2/en not_active Ceased
- 1996-05-30 AT AT96916910T patent/ATE225200T1/en not_active IP Right Cessation
- 1996-05-30 CN CN96194375A patent/CN1099300C/en not_active Expired - Fee Related
- 1996-05-30 DK DK96916910T patent/DK0830176T3/en active
- 1996-05-30 MX MX9709365A patent/MX9709365A/en not_active IP Right Cessation
- 1996-05-30 CA CA002217711A patent/CA2217711C/en not_active Expired - Fee Related
- 1996-05-30 PT PT96916910T patent/PT830176E/en unknown
- 1996-05-30 EP EP96916910A patent/EP0830176B1/en not_active Expired - Lifetime
- 1996-05-30 CH CH02788/97A patent/CH690818A5/en not_active IP Right Cessation
- 1996-05-30 KR KR1019970708300A patent/KR100454667B1/en not_active IP Right Cessation
- 1996-05-30 JP JP8536747A patent/JPH11511677A/en active Pending
- 1996-05-30 DE DE69624109T patent/DE69624109T2/en not_active Expired - Lifetime
-
1997
- 1997-09-29 US US08/939,921 patent/US6035234A/en not_active Expired - Lifetime
- 1997-12-02 SE SE9704478A patent/SE520344C2/en not_active IP Right Cessation
-
2001
- 2001-12-26 US US10/025,980 patent/US20020087193A1/en not_active Abandoned
-
2002
- 2002-09-25 US US10/253,419 patent/US6842640B2/en not_active Expired - Fee Related
-
2004
- 2004-11-30 US US10/999,504 patent/US7708731B2/en not_active Expired - Fee Related
Also Published As
Publication number | Publication date |
---|---|
KR19990014954A (en) | 1999-02-25 |
DE19681422T1 (en) | 1998-05-20 |
CN1186449A (en) | 1998-07-01 |
SE520344C2 (en) | 2003-07-01 |
CN1099300C (en) | 2003-01-22 |
US6035234A (en) | 2000-03-07 |
DE69624109T2 (en) | 2003-06-18 |
AU5963096A (en) | 1996-12-18 |
DE69624109D1 (en) | 2002-11-07 |
US20050075623A1 (en) | 2005-04-07 |
KR100454667B1 (en) | 2005-01-17 |
ATE225200T1 (en) | 2002-10-15 |
JPH11511677A (en) | 1999-10-12 |
US6842640B2 (en) | 2005-01-11 |
CA2217711C (en) | 2009-05-19 |
EP0830176B1 (en) | 2002-10-02 |
AT408616B (en) | 2002-01-25 |
CH690818A5 (en) | 2001-01-31 |
DK0830176T3 (en) | 2003-02-03 |
SE9704478L (en) | 1997-12-02 |
ES2184867T3 (en) | 2003-04-16 |
MX9709365A (en) | 1998-02-28 |
US20030018296A1 (en) | 2003-01-23 |
SE9704478D0 (en) | 1997-12-02 |
BE1009518A5 (en) | 1997-04-01 |
US20020087193A1 (en) | 2002-07-04 |
ATA903496A (en) | 2001-06-15 |
WO1996038199A1 (en) | 1996-12-05 |
EP0830176A1 (en) | 1998-03-25 |
PT830176E (en) | 2003-02-28 |
US7708731B2 (en) | 2010-05-04 |
AU700477B2 (en) | 1999-01-07 |
IE960312A1 (en) | 1996-12-11 |
Similar Documents
Publication | Publication Date | Title |
---|---|---|
CA2217711A1 (en) | Electrotransport delivery with voltage boosting circuit | |
AU6608400A (en) | High pulse rate pulse power system with fast rise time and low leakage current | |
AU6271296A (en) | Electrotransport agent delivery method and apparatus | |
EP1046407A2 (en) | Device for iontophoresis | |
EP1109595A4 (en) | Method and apparatus for low power, regulated output in battery powered electrotherapy devices | |
CA2136337A1 (en) | Electrical Stimulation for Treatment of Incontinence and Other Neuro-Muscular Disorders | |
HK1045217A1 (en) | Opto-electrical devices | |
WO2003051453A3 (en) | Device for muscle stimulation | |
EP0878982A3 (en) | High voltage discharge lamp device | |
SE9300306D0 (en) | SETTING TO REGULATE POWER SUPPLY TO AN ELECTROSTATIC DUST DISPENSER | |
BR0303573A (en) | Automatic or semi-automatic external defibrillator, automatic or semi-automatic external defibrillator system, power supply for an automatic or semi-automatic external defibrillator, and method | |
ATE290417T1 (en) | IMPLANTABLE THREE PHASE WAVEFORM DEFIBRILLATOR | |
EP0577987A3 (en) | Device for controlling the output voltage of an engine-driven generator. | |
CA2247681A1 (en) | Methods for implementing current delivery profiles used in an iontophoretic system | |
US5256137A (en) | Biphasic power source for use in an iontophoretic drug delivery system | |
WO1999027990A3 (en) | Stereospecific delivery of a drug using electrotransport | |
IL105073A0 (en) | User activated iontophoretic device and method for using same | |
SG81867A1 (en) | Voltage regulator for crt electrode supply | |
TR27201A (en) | Voltage boosting device for CRT electrode supply unit. | |
AU643760B2 (en) | Method and composition for increased skin concentration of active agents by iontophoresis | |
JPS521444A (en) | Constant current power supply system | |
IT1240713B (en) | Multichannel electrical stimulation device, specifically for the neuromuscular system | |
JPS53102242A (en) | All position welding method | |
CA2042994A1 (en) | Iontophoretic delivery device | |
EP0776724A3 (en) | Electrical discharge power supply circuit |
Legal Events
Date | Code | Title | Description |
---|---|---|---|
EEER | Examination request | ||
MKLA | Lapsed |