CA2257254A1 - Antibiotic producing microbe - Google Patents
Antibiotic producing microbeInfo
- Publication number
- CA2257254A1 CA2257254A1 CA002257254A CA2257254A CA2257254A1 CA 2257254 A1 CA2257254 A1 CA 2257254A1 CA 002257254 A CA002257254 A CA 002257254A CA 2257254 A CA2257254 A CA 2257254A CA 2257254 A1 CA2257254 A1 CA 2257254A1
- Authority
- CA
- Canada
- Prior art keywords
- producing microbe
- antibiotic producing
- microbe
- cyclosporin
- antibiotic
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Granted
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K7/00—Peptides having 5 to 20 amino acids in a fully defined sequence; Derivatives thereof
- C07K7/64—Cyclic peptides containing only normal peptide links
- C07K7/645—Cyclosporins; Related peptides
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K38/00—Medicinal preparations containing peptides
-
- Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
- Y10—TECHNICAL SUBJECTS COVERED BY FORMER USPC
- Y10S—TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
- Y10S435/00—Chemistry: molecular biology and microbiology
- Y10S435/8215—Microorganisms
- Y10S435/911—Microorganisms using fungi
Abstract
A cyclosporin-producing microbe is described. A process for the production of cyclosporin, comprising culturing the microbe and recovering the desired form of cyclosporin produced, is described.
Applications Claiming Priority (3)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
US08/658,653 | 1996-06-05 | ||
US08/658,653 US5747330A (en) | 1996-06-05 | 1996-06-05 | Antibiotic producing microbe |
PCT/IB1997/000654 WO1997046580A1 (en) | 1996-06-05 | 1997-06-05 | Antibiotic producing microbe |
Publications (2)
Publication Number | Publication Date |
---|---|
CA2257254A1 true CA2257254A1 (en) | 1997-12-11 |
CA2257254C CA2257254C (en) | 2002-08-13 |
Family
ID=24642117
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
CA002257254A Expired - Fee Related CA2257254C (en) | 1996-06-05 | 1997-06-05 | Antibiotic producing microbe |
Country Status (8)
Country | Link |
---|---|
US (2) | US5747330A (en) |
EP (1) | EP0906336B1 (en) |
AT (1) | ATE275153T1 (en) |
AU (1) | AU2912297A (en) |
CA (1) | CA2257254C (en) |
DE (1) | DE69730497D1 (en) |
ES (1) | ES2227693T3 (en) |
WO (2) | WO1997046575A1 (en) |
Families Citing this family (12)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US6176701B1 (en) * | 1997-10-01 | 2001-01-23 | Barnett Joel Robinson | Method for improving fuel efficiency in combustion chambers |
US20030220234A1 (en) * | 1998-11-02 | 2003-11-27 | Selvaraj Naicker | Deuterated cyclosporine analogs and their use as immunodulating agents |
AU750245B2 (en) | 1997-10-08 | 2002-07-11 | Aurinia Phamaceuticals Inc. | Deuterated cyclosporine analogs and their use as immunomodulating agents |
DE69939335D1 (en) | 1998-12-30 | 2008-09-25 | Dexcel Ltd | DISPERSIBLE CONCENTRATE FOR THE ADMINISTRATION OF CYCLOSPORIN |
US7732404B2 (en) * | 1999-12-30 | 2010-06-08 | Dexcel Ltd | Pro-nanodispersion for the delivery of cyclosporin |
DE60023189D1 (en) | 2000-02-29 | 2006-02-23 | Biocon Ltd | PREPARATION AND CLEANING OF CYCLOSPORIN-A |
US6547900B2 (en) | 2001-01-24 | 2003-04-15 | Breed Automotive Technology, Inc. | Method of stabilizing the density of gas generant pellets containing nitroguanidine |
PL210795B1 (en) | 2001-10-19 | 2012-03-30 | Isotechnika Inc | The method of producing the ISATX247 enriched isomer (E), the method of producing the ISATX247 enriched mixture of the (Z) isomer, the method of stereoselective synthesis of the (E) ISATX247 isomer, the method of stereoselective synthesis of the (Z) isomer ISATX247 and the method of producing the mixture of ISATX247 isomers |
KR101072121B1 (en) | 2008-02-19 | 2011-10-10 | (주)차바이오앤디오스텍 | Method for mass culture of cyclosporine at Tolypocladium niveum |
EP2151450A1 (en) | 2008-07-29 | 2010-02-10 | Sandoz AG | Method for processing microbiologically produced cyclic oligopeptides |
US10945443B2 (en) | 2017-09-29 | 2021-03-16 | Valent Biosciences Llc | Tolypocladium album strain |
CN115125148A (en) * | 2021-03-24 | 2022-09-30 | 宁夏泰胜生物科技有限公司 | Culture medium and culture method for producing cyclosporine by fermentation of Sinkiang saururi |
Family Cites Families (18)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US4117118A (en) * | 1976-04-09 | 1978-09-26 | Sandoz Ltd. | Organic compounds |
CH633826A5 (en) * | 1977-04-06 | 1982-12-31 | Sandoz Ag | Process for the preparation of a novel antibiotic |
DE2819094A1 (en) * | 1977-05-10 | 1978-11-23 | Sandoz Ag | CYCLOSPORIN DERIVATIVES, THEIR USE AND MANUFACTURING |
US4215199A (en) * | 1978-06-05 | 1980-07-29 | Sandoz Ltd. | Antibiotic production |
SE448386B (en) * | 1978-10-18 | 1987-02-16 | Sandoz Ag | NEW CYCLOSPORIN DERIVATIVES, PROCEDURE FOR PREPARING THEM AND PHARMACEUTICAL COMPOSITION CONTAINING THEM |
DE3260468D1 (en) * | 1981-01-09 | 1984-09-06 | Sandoz Ag | Novel cyclosporins |
JPS5877894A (en) * | 1981-11-05 | 1983-05-11 | Mitsui Toatsu Chem Inc | Removing method of protein |
CH667274A5 (en) * | 1984-03-23 | 1988-09-30 | Sandoz Ag | CYCLOSPORINE, THEIR PRODUCTION AND PHARMACEUTICAL COMPOSITIONS CONTAINING THEM. |
EP0373260B1 (en) * | 1987-06-22 | 1994-03-09 | Merck & Co. Inc. | Cyclosporin derivatives with modified "8-amino acid" |
HU201577B (en) * | 1988-12-20 | 1990-11-28 | Gyogyszerkutato Intezet | Process for producing cyclosporin antibiotics |
JPH02216453A (en) * | 1989-02-17 | 1990-08-29 | Sekisui Chem Co Ltd | Method for measuring cyclosporin |
EP0568698B1 (en) * | 1991-01-25 | 1997-09-10 | Fujisawa Pharmaceutical Co., Ltd. | Process for producing cyclosporin a and/or c |
ES2078374T3 (en) * | 1991-04-06 | 1995-12-16 | Dresden Arzneimittel | PROCEDURE FOR THE PRODUCTION BY FERMENTATION AND ISOLATION OF CYCLOSPORINE A, AND NEW STRAINS FORMING CYCLOSPORIN. |
HU213553B (en) * | 1992-05-25 | 1997-07-28 | Biogal Gyogyszergyar | Process for isolating of cyclosporin-a |
FI92334C (en) * | 1992-12-30 | 1994-10-25 | Leiras Oy | Process for producing cyclosporins and new Tolypocladium strain useful in the process |
FR2723846B1 (en) * | 1994-08-24 | 1997-06-13 | Hi Pharmtech | SOLID PHARMACEUTICAL FORM FOR THE ADMINISTRATION OF A LIPOSOLUBLE LIQUID ACTIVE SUBSTANCE |
KR100304324B1 (en) * | 1994-10-13 | 2001-11-22 | 김용규 | Method for manufacturing cyclosporine a |
KR0126610B1 (en) * | 1994-10-18 | 1997-12-29 | 김충환 | Producing method of cyclosporina by cell fusioned microorganism |
-
1996
- 1996-06-05 US US08/658,653 patent/US5747330A/en not_active Expired - Lifetime
-
1997
- 1997-03-05 US US08/810,077 patent/US5801020A/en not_active Expired - Lifetime
- 1997-06-05 ES ES97923272T patent/ES2227693T3/en not_active Expired - Lifetime
- 1997-06-05 EP EP97923272A patent/EP0906336B1/en not_active Expired - Lifetime
- 1997-06-05 WO PCT/IB1997/000914 patent/WO1997046575A1/en not_active Application Discontinuation
- 1997-06-05 DE DE69730497T patent/DE69730497D1/en not_active Expired - Lifetime
- 1997-06-05 CA CA002257254A patent/CA2257254C/en not_active Expired - Fee Related
- 1997-06-05 WO PCT/IB1997/000654 patent/WO1997046580A1/en active IP Right Grant
- 1997-06-05 AT AT97923272T patent/ATE275153T1/en not_active IP Right Cessation
- 1997-06-05 AU AU29122/97A patent/AU2912297A/en not_active Abandoned
Also Published As
Publication number | Publication date |
---|---|
WO1997046575A1 (en) | 1997-12-11 |
EP0906336A1 (en) | 1999-04-07 |
DE69730497D1 (en) | 2004-10-07 |
CA2257254C (en) | 2002-08-13 |
WO1997046580A1 (en) | 1997-12-11 |
AU2912297A (en) | 1998-01-05 |
US5747330A (en) | 1998-05-05 |
EP0906336B1 (en) | 2004-09-01 |
ES2227693T3 (en) | 2005-04-01 |
ATE275153T1 (en) | 2004-09-15 |
US5801020A (en) | 1998-09-01 |
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Legal Events
Date | Code | Title | Description |
---|---|---|---|
EEER | Examination request | ||
MKLA | Lapsed |
Effective date: 20160606 |