CA2270995A1 - Improvements in or relating to screening for papilloma viruses - Google Patents
Improvements in or relating to screening for papilloma virusesInfo
- Publication number
- CA2270995A1 CA2270995A1 CA002270995A CA2270995A CA2270995A1 CA 2270995 A1 CA2270995 A1 CA 2270995A1 CA 002270995 A CA002270995 A CA 002270995A CA 2270995 A CA2270995 A CA 2270995A CA 2270995 A1 CA2270995 A1 CA 2270995A1
- Authority
- CA
- Canada
- Prior art keywords
- screening
- relating
- papilloma viruses
- organism
- patient
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Granted
Links
Classifications
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
- G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
- G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
- G01N33/53—Immunoassay; Biospecific binding assay; Materials therefor
- G01N33/569—Immunoassay; Biospecific binding assay; Materials therefor for microorganisms, e.g. protozoa, bacteria, viruses
- G01N33/56983—Viruses
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K16/00—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies
- C07K16/08—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from viruses
- C07K16/081—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from viruses from DNA viruses
- C07K16/084—Papovaviridae, e.g. papillomavirus, polyomavirus, SV40, BK virus, JC virus
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K2317/00—Immunoglobulins specific features
- C07K2317/30—Immunoglobulins specific features characterized by aspects of specificity or valency
- C07K2317/34—Identification of a linear epitope shorter than 20 amino acid residues or of a conformational epitope defined by amino acid residues
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K2317/00—Immunoglobulins specific features
- C07K2317/50—Immunoglobulins specific features characterized by immunoglobulin fragments
- C07K2317/55—Fab or Fab'
Abstract
Disclosed is a method of detecting a papilloma virus infection in an organism, the method comprising the steps of: obtaining a sample of the organism's cells from the site of potential infection; contacting the cells with a molecule that binds specifically to papilloma virus E4 protein; and monitoring said binding, together with a method of determining the types) of HPV infecting a patient, a method of screening a patient for the presence of a precancerous cervical lesion, and an antibody molecule of use in one of the above methods.
Applications Claiming Priority (5)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
GB9625142A GB9625142D0 (en) | 1996-12-03 | 1996-12-03 | Virus identification |
GB9625142.6 | 1996-12-03 | ||
GB9718745.4 | 1997-09-05 | ||
GBGB9718745.4A GB9718745D0 (en) | 1996-12-03 | 1997-09-05 | Improvements in or relating to screening for carcinoma |
PCT/GB1997/003321 WO1998025145A1 (en) | 1996-12-03 | 1997-12-03 | Improvements in or relating to screening for papilloma viruses |
Publications (2)
Publication Number | Publication Date |
---|---|
CA2270995A1 true CA2270995A1 (en) | 1998-06-11 |
CA2270995C CA2270995C (en) | 2006-10-10 |
Family
ID=26310537
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
CA002270995A Expired - Fee Related CA2270995C (en) | 1996-12-03 | 1997-12-03 | Improvements in or relating to screening for papilloma viruses |
Country Status (11)
Country | Link |
---|---|
US (2) | US6346377B1 (en) |
EP (1) | EP1021722B1 (en) |
JP (1) | JP4206133B2 (en) |
AT (1) | ATE299594T1 (en) |
AU (1) | AU744391B2 (en) |
CA (1) | CA2270995C (en) |
DE (1) | DE69733721T2 (en) |
DK (1) | DK1021722T3 (en) |
ES (1) | ES2242236T3 (en) |
GB (1) | GB9718745D0 (en) |
WO (1) | WO1998025145A1 (en) |
Families Citing this family (27)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
GB9718745D0 (en) * | 1996-12-03 | 1997-11-12 | Medical Res Council | Improvements in or relating to screening for carcinoma |
US6303323B1 (en) * | 1997-10-21 | 2001-10-16 | Cancer Research Campaign Technology Limited | Detection of dysplastic or neoplastic cells using anti-MCM5 antibodies |
PT1179176E (en) * | 1999-04-16 | 2006-07-31 | Ortho Mcneil Pharm Inc | METHOD FOR DETECTING T-CELLS SPECIFIC TO ANTIGEN |
GB0018140D0 (en) * | 2000-07-24 | 2000-09-13 | Medical Res Council | Screening for abnormalities |
US20070031826A1 (en) * | 2005-08-05 | 2007-02-08 | My Gene | Diagnostic kit for determining the genotype of a human papilloma virus and method of using thereof |
US20100279422A1 (en) * | 2006-08-21 | 2010-11-04 | Cmed Technologies Ltd. | Method of surface plasmon resonance (spr) technology to detect genomic disorders for prenatal diagnosis |
WO2008036465A2 (en) * | 2006-09-18 | 2008-03-27 | CMED Technologies Ltd. Office of Walkers Limited | A method to assess cancer susceptibility and differential diagnosis of metastases of unknown primary tumors |
WO2008036470A2 (en) * | 2006-09-19 | 2008-03-27 | Cmed Technologies Ltd. | A method for screening of infectious agents in blood |
US20100021971A1 (en) * | 2006-09-21 | 2010-01-28 | Cmed Technologies Ltd. | Method to remove repetitive sequences from human dna |
US20100047815A1 (en) * | 2006-09-21 | 2010-02-25 | Cmed Technologies Ltd. | Method to detect tumor markers and diagnosis of undifferentiated tumors |
WO2008085554A2 (en) * | 2006-09-25 | 2008-07-17 | Cmed Technologies Ltd. | A method to detect virus related immunologigal markers for the diagnosis of hepatitis b virus infection |
US8119350B2 (en) * | 2006-09-25 | 2012-02-21 | Cmed Technologies Ltd | Method of surface plasmon resonance (SPR) to detect genomic aberrations in patients with multiple myeloma |
US20090311699A1 (en) * | 2006-09-25 | 2009-12-17 | Cmed Technologies Ltd. | Method of surface plasmon resonance (spr) to detect genomic aberrations in patients with chronic lymphocytic leukemia |
WO2008070227A2 (en) * | 2006-09-25 | 2008-06-12 | Cmed Technologies Ltd. | A method for the identification of human immunodeficiency virus related antibodies in blood |
US20100041018A1 (en) * | 2006-09-25 | 2010-02-18 | Cmed Technologies Ltd. | Method to detect virus related immunological markers for the diagnosis of hepatitis c virus infection |
US20100047789A1 (en) * | 2006-09-25 | 2010-02-25 | Cmed Technologies Ltd. | Method of surface plasmon resonance (spr) to detect genomic disorders for postnatal diagnosis |
WO2008066994A2 (en) * | 2006-09-27 | 2008-06-05 | Cmed Technologies Ltd. | Application of surface plasmon resonance technology to maternal serum screening for congenital birth defects |
WO2008067003A2 (en) * | 2006-09-27 | 2008-06-05 | Cmed Technologies Ltd. | A method to detect virus related immunological markers for the diagnosis of respiratory tract infections |
WO2008066997A2 (en) * | 2006-09-27 | 2008-06-05 | Cmed Technologies Ltd. | A method for quantitative measurement of cardiac biochemical markers |
WO2008067008A2 (en) * | 2006-09-27 | 2008-06-05 | Cmed Technologies Ltd. | A method for the quantitative evaluation of sex hormones in a serum sample |
WO2008066996A2 (en) * | 2006-09-27 | 2008-06-05 | Cmed Technologies Ltd. | A method to detect treponema pallidum immunological markers for the diagnosis of syphilis |
WO2008070241A2 (en) * | 2006-09-27 | 2008-06-12 | Cmed Technologies Ltd. | A method to measure serum biomarkers for the diagnosis of liver fibrosis |
GB2456690B (en) * | 2006-09-28 | 2012-01-25 | Cytotrend Biotech Engineering Ltd Usa Inc | A method for quantitative detection of diabetes related immunological markers |
US8158440B2 (en) * | 2006-09-28 | 2012-04-17 | Cmed Technologies Ltd. | Method for quantitative measurement of thyroid related antibodies or antigens in a serum sample |
US7838215B2 (en) * | 2007-09-25 | 2010-11-23 | Canvir, Inc. | Advanced cervical cell screening methods |
US8168379B2 (en) | 2007-10-04 | 2012-05-01 | Cmed Technologies Ltd. | Application of surface plasmon resonance technology for detecting and genotyping HPV |
GB0820720D0 (en) * | 2008-11-12 | 2008-12-17 | Norchip As | Method for worldwide screening of pre-cancer epithelial disease of the cervix |
Family Cites Families (4)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US4777239A (en) * | 1986-07-10 | 1988-10-11 | The Board Of Trustees Of The Leland Stanford Junior University | Diagnostic peptides of human papilloma virus |
CA2038581A1 (en) * | 1990-03-20 | 1991-09-21 | Martin Muller | Seroreactive epitopes of human papillomavirus (hpv) 16 proteins |
SE9001705D0 (en) * | 1990-05-11 | 1990-05-11 | Medscand Ab | SET FOR DIAGNOSTICS OF VIRUS BREAKING TUMORS BY IMMUNOASSAY |
GB9718745D0 (en) * | 1996-12-03 | 1997-11-12 | Medical Res Council | Improvements in or relating to screening for carcinoma |
-
1997
- 1997-09-05 GB GBGB9718745.4A patent/GB9718745D0/en active Pending
- 1997-12-03 EP EP97947162A patent/EP1021722B1/en not_active Expired - Lifetime
- 1997-12-03 AU AU52311/98A patent/AU744391B2/en not_active Ceased
- 1997-12-03 WO PCT/GB1997/003321 patent/WO1998025145A1/en active IP Right Grant
- 1997-12-03 DE DE69733721T patent/DE69733721T2/en not_active Expired - Lifetime
- 1997-12-03 CA CA002270995A patent/CA2270995C/en not_active Expired - Fee Related
- 1997-12-03 JP JP52534498A patent/JP4206133B2/en not_active Expired - Fee Related
- 1997-12-03 ES ES97947162T patent/ES2242236T3/en not_active Expired - Lifetime
- 1997-12-03 AT AT97947162T patent/ATE299594T1/en not_active IP Right Cessation
- 1997-12-03 DK DK97947162T patent/DK1021722T3/en active
-
1999
- 1999-05-18 US US09/314,268 patent/US6346377B1/en not_active Expired - Fee Related
-
2001
- 2001-11-05 US US10/008,524 patent/US7135281B2/en not_active Expired - Fee Related
Also Published As
Publication number | Publication date |
---|---|
GB9718745D0 (en) | 1997-11-12 |
DK1021722T3 (en) | 2005-08-08 |
JP2001509886A (en) | 2001-07-24 |
EP1021722B1 (en) | 2005-07-13 |
EP1021722A1 (en) | 2000-07-26 |
CA2270995C (en) | 2006-10-10 |
AU744391B2 (en) | 2002-02-21 |
AU5231198A (en) | 1998-06-29 |
ATE299594T1 (en) | 2005-07-15 |
WO1998025145A1 (en) | 1998-06-11 |
JP4206133B2 (en) | 2009-01-07 |
ES2242236T3 (en) | 2005-11-01 |
US7135281B2 (en) | 2006-11-14 |
DE69733721D1 (en) | 2005-08-18 |
DE69733721T2 (en) | 2006-05-18 |
US6346377B1 (en) | 2002-02-12 |
US20030175682A1 (en) | 2003-09-18 |
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Legal Events
Date | Code | Title | Description |
---|---|---|---|
EEER | Examination request | ||
MKLA | Lapsed |
Effective date: 20141203 |