CA2278176A1 - Novel minerals and methods for their production and use - Google Patents

Novel minerals and methods for their production and use Download PDF

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Publication number
CA2278176A1
CA2278176A1 CA002278176A CA2278176A CA2278176A1 CA 2278176 A1 CA2278176 A1 CA 2278176A1 CA 002278176 A CA002278176 A CA 002278176A CA 2278176 A CA2278176 A CA 2278176A CA 2278176 A1 CA2278176 A1 CA 2278176A1
Authority
CA
Canada
Prior art keywords
oxoacid
anion
anions
precipitant
production
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Granted
Application number
CA002278176A
Other languages
French (fr)
Other versions
CA2278176C (en
Inventor
Ronald S. Sapieszko
Erik M. Erbe
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Orthovita Inc
Original Assignee
Orthovita, Inc.
Ronald S. Sapieszko
Erik M. Erbe
Vita Licensing, Inc.
Vita Special Purpose Corporation
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Orthovita, Inc., Ronald S. Sapieszko, Erik M. Erbe, Vita Licensing, Inc., Vita Special Purpose Corporation filed Critical Orthovita, Inc.
Publication of CA2278176A1 publication Critical patent/CA2278176A1/en
Application granted granted Critical
Publication of CA2278176C publication Critical patent/CA2278176C/en
Anticipated expiration legal-status Critical
Expired - Fee Related legal-status Critical Current

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
    • A61L27/00—Materials for grafts or prostheses or for coating grafts or prostheses
    • A61L27/02—Inorganic materials
    • A61L27/12—Phosphorus-containing materials, e.g. apatite
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K6/00—Preparations for dentistry
    • A61K6/15—Compositions characterised by their physical properties
    • A61K6/17—Particle size
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K6/00—Preparations for dentistry
    • A61K6/60—Preparations for dentistry comprising organic or organo-metallic additives
    • A61K6/69—Medicaments
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K6/00—Preparations for dentistry
    • A61K6/70—Preparations for dentistry comprising inorganic additives
    • A61K6/71—Fillers
    • A61K6/74—Fillers comprising phosphorus-containing compounds
    • A61K6/75—Apatite
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K6/00—Preparations for dentistry
    • A61K6/70—Preparations for dentistry comprising inorganic additives
    • A61K6/71—Fillers
    • A61K6/77—Glass
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K6/00—Preparations for dentistry
    • A61K6/70—Preparations for dentistry comprising inorganic additives
    • A61K6/78—Pigments
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K6/00—Preparations for dentistry
    • A61K6/80—Preparations for artificial teeth, for filling teeth or for capping teeth
    • A61K6/831—Preparations for artificial teeth, for filling teeth or for capping teeth comprising non-metallic elements or compounds thereof, e.g. carbon
    • A61K6/833—Glass-ceramic composites
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K6/00—Preparations for dentistry
    • A61K6/80—Preparations for artificial teeth, for filling teeth or for capping teeth
    • A61K6/849—Preparations for artificial teeth, for filling teeth or for capping teeth comprising inorganic cements
    • A61K6/864—Phosphate cements
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
    • A61L24/00—Surgical adhesives or cements; Adhesives for colostomy devices
    • A61L24/02—Surgical adhesives or cements; Adhesives for colostomy devices containing inorganic materials
    • C—CHEMISTRY; METALLURGY
    • C01—INORGANIC CHEMISTRY
    • C01B—NON-METALLIC ELEMENTS; COMPOUNDS THEREOF; METALLOIDS OR COMPOUNDS THEREOF NOT COVERED BY SUBCLASS C01C
    • C01B25/00—Phosphorus; Compounds thereof
    • C01B25/16—Oxyacids of phosphorus; Salts thereof
    • C01B25/26—Phosphates
    • C01B25/32—Phosphates of magnesium, calcium, strontium, or barium
    • C01B25/324—Preparation from a reaction solution obtained by acidifying with an acid other than orthophosphoric acid
    • C—CHEMISTRY; METALLURGY
    • C01—INORGANIC CHEMISTRY
    • C01B—NON-METALLIC ELEMENTS; COMPOUNDS THEREOF; METALLOIDS OR COMPOUNDS THEREOF NOT COVERED BY SUBCLASS C01C
    • C01B25/00—Phosphorus; Compounds thereof
    • C01B25/16—Oxyacids of phosphorus; Salts thereof
    • C01B25/26—Phosphates
    • C01B25/36—Aluminium phosphates
    • C—CHEMISTRY; METALLURGY
    • C01—INORGANIC CHEMISTRY
    • C01B—NON-METALLIC ELEMENTS; COMPOUNDS THEREOF; METALLOIDS OR COMPOUNDS THEREOF NOT COVERED BY SUBCLASS C01C
    • C01B25/00—Phosphorus; Compounds thereof
    • C01B25/16—Oxyacids of phosphorus; Salts thereof
    • C01B25/26—Phosphates
    • C01B25/37—Phosphates of heavy metals
    • C—CHEMISTRY; METALLURGY
    • C01—INORGANIC CHEMISTRY
    • C01B—NON-METALLIC ELEMENTS; COMPOUNDS THEREOF; METALLOIDS OR COMPOUNDS THEREOF NOT COVERED BY SUBCLASS C01C
    • C01B25/00—Phosphorus; Compounds thereof
    • C01B25/16—Oxyacids of phosphorus; Salts thereof
    • C01B25/26—Phosphates
    • C01B25/37—Phosphates of heavy metals
    • C01B25/375—Phosphates of heavy metals of iron
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61F—FILTERS IMPLANTABLE INTO BLOOD VESSELS; PROSTHESES; DEVICES PROVIDING PATENCY TO, OR PREVENTING COLLAPSING OF, TUBULAR STRUCTURES OF THE BODY, e.g. STENTS; ORTHOPAEDIC, NURSING OR CONTRACEPTIVE DEVICES; FOMENTATION; TREATMENT OR PROTECTION OF EYES OR EARS; BANDAGES, DRESSINGS OR ABSORBENT PADS; FIRST-AID KITS
    • A61F2310/00—Prostheses classified in A61F2/28 or A61F2/30 - A61F2/44 being constructed from or coated with a particular material
    • A61F2310/00005—The prosthesis being constructed from a particular material
    • A61F2310/00179—Ceramics or ceramic-like structures
    • A61F2310/00293—Ceramics or ceramic-like structures containing a phosphorus-containing compound, e.g. apatite

Abstract

Uniformly sized and shaped particles of metal salts are provided comprised of one or more metal cations in combination with one or more simple oxoacid anions and a general method for the controlled precipitation of said metal salts from aqueous solutions. The methods proceed via the in situ homogeneous production of simple or complex oxoacid anions in which one or more of the nonmetallic elements e.g. Group 5B and 6B (chalcogenides), and 7B (halides) comprising the first oxoacid anion undergo oxidation to generate the precipitant anionic species along with concurrent reduction of the nonmetallic element of a second, dissimilar oxoacid anion. The oxoacid anions are initially present in solution with one or more metal cations known to form insoluble salts with the precipitant anion.
CA002278176A 1997-01-16 1998-01-13 Novel minerals and methods for their production and use Expired - Fee Related CA2278176C (en)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US08/784,439 1997-01-16
US08/784,439 US5939039A (en) 1997-01-16 1997-01-16 Methods for production of calcium phosphate
PCT/US1998/000527 WO1998031630A1 (en) 1997-01-16 1998-01-13 Novel minerals and methods for their production and use

Publications (2)

Publication Number Publication Date
CA2278176A1 true CA2278176A1 (en) 1998-07-23
CA2278176C CA2278176C (en) 2005-04-12

Family

ID=25132461

Family Applications (1)

Application Number Title Priority Date Filing Date
CA002278176A Expired - Fee Related CA2278176C (en) 1997-01-16 1998-01-13 Novel minerals and methods for their production and use

Country Status (14)

Country Link
US (3) US5939039A (en)
EP (1) EP0980338B1 (en)
JP (2) JP4135990B2 (en)
KR (1) KR20000070171A (en)
AT (1) ATE271523T1 (en)
AU (1) AU730352B2 (en)
CA (1) CA2278176C (en)
DE (1) DE69825156T2 (en)
ES (1) ES2226094T3 (en)
IL (1) IL130738A0 (en)
PT (1) PT980338E (en)
TW (1) TW442440B (en)
WO (1) WO1998031630A1 (en)
ZA (1) ZA9711219B (en)

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US9789225B2 (en) 2004-06-23 2017-10-17 Orthovita, Inc. Shapeable bone graft substitute and instruments for delivery thereof

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US10441683B2 (en) 2004-06-23 2019-10-15 Orthovita, Inc. Method for restoring bone using shapeable bone graft substitute and instruments for delivery thereof

Also Published As

Publication number Publication date
US6325987B1 (en) 2001-12-04
AU5913798A (en) 1998-08-07
JP2000512971A (en) 2000-10-03
US5939039A (en) 1999-08-17
EP0980338A4 (en) 2000-02-23
EP0980338B1 (en) 2004-07-21
DE69825156D1 (en) 2004-08-26
EP0980338A1 (en) 2000-02-23
AU730352B2 (en) 2001-03-08
TW442440B (en) 2001-06-23
KR20000070171A (en) 2000-11-25
JP4987655B2 (en) 2012-07-25
CA2278176C (en) 2005-04-12
ATE271523T1 (en) 2004-08-15
WO1998031630A1 (en) 1998-07-23
IL130738A0 (en) 2000-06-01
ES2226094T3 (en) 2005-03-16
US20020039552A1 (en) 2002-04-04
ZA9711219B (en) 1998-06-23
PT980338E (en) 2004-10-29
JP2008050260A (en) 2008-03-06
US6969501B2 (en) 2005-11-29
JP4135990B2 (en) 2008-08-20
DE69825156T2 (en) 2005-07-28

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