CA2314562A1 - Reducing hair growth, hair follicle and hair shaft size and hair pigmentation - Google Patents

Reducing hair growth, hair follicle and hair shaft size and hair pigmentation Download PDF

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Publication number
CA2314562A1
CA2314562A1 CA002314562A CA2314562A CA2314562A1 CA 2314562 A1 CA2314562 A1 CA 2314562A1 CA 002314562 A CA002314562 A CA 002314562A CA 2314562 A CA2314562 A CA 2314562A CA 2314562 A1 CA2314562 A1 CA 2314562A1
Authority
CA
Canada
Prior art keywords
composition
hair
powder
isoflavones
amount
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Granted
Application number
CA002314562A
Other languages
French (fr)
Other versions
CA2314562C (en
Inventor
Miri Seiberg
Stanley S. Shapiro
Jue-Chen Liu
Jonathan Miller
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Johnson and Johnson Consumer Inc
Original Assignee
Johnson and Johnson Consumer Companies LLC
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
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Application filed by Johnson and Johnson Consumer Companies LLC filed Critical Johnson and Johnson Consumer Companies LLC
Publication of CA2314562A1 publication Critical patent/CA2314562A1/en
Application granted granted Critical
Publication of CA2314562C publication Critical patent/CA2314562C/en
Anticipated expiration legal-status Critical
Expired - Fee Related legal-status Critical Current

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Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K8/00—Cosmetics or similar toiletry preparations
    • A61K8/18—Cosmetics or similar toiletry preparations characterised by the composition
    • A61K8/96—Cosmetics or similar toiletry preparations characterised by the composition containing materials, or derivatives thereof of undetermined constitution
    • A61K8/97—Cosmetics or similar toiletry preparations characterised by the composition containing materials, or derivatives thereof of undetermined constitution from algae, fungi, lichens or plants; from derivatives thereof
    • A61K8/9783—Angiosperms [Magnoliophyta]
    • A61K8/9789—Magnoliopsida [dicotyledons]
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K8/00—Cosmetics or similar toiletry preparations
    • A61K8/18—Cosmetics or similar toiletry preparations characterised by the composition
    • A61K8/96—Cosmetics or similar toiletry preparations characterised by the composition containing materials, or derivatives thereof of undetermined constitution
    • A61K8/97—Cosmetics or similar toiletry preparations characterised by the composition containing materials, or derivatives thereof of undetermined constitution from algae, fungi, lichens or plants; from derivatives thereof
    • A61K8/9783—Angiosperms [Magnoliophyta]
    • A61K8/9794—Liliopsida [monocotyledons]
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P17/00—Drugs for dermatological disorders
    • A61P17/14—Drugs for dermatological disorders for baldness or alopecia
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61Q—SPECIFIC USE OF COSMETICS OR SIMILAR TOILETRY PREPARATIONS
    • A61Q5/00—Preparations for care of the hair
    • A61Q5/08—Preparations for bleaching the hair
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61Q—SPECIFIC USE OF COSMETICS OR SIMILAR TOILETRY PREPARATIONS
    • A61Q7/00—Preparations for affecting hair growth
    • A61Q7/02—Preparations for inhibiting or slowing hair growth
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K2800/00—Properties of cosmetic compositions or active ingredients thereof or formulation aids used therein and process related aspects
    • A61K2800/74—Biological properties of particular ingredients
    • A61K2800/78—Enzyme modulators, e.g. Enzyme agonists
    • A61K2800/782—Enzyme inhibitors; Enzyme antagonists

Abstract

The present invention utilizes natural and/or synthetic serine protease inhibitory agents or botanical extracts containing serine protease inhibitory activity, with or without the addition of one or more isoflavones and/or additional natural extracts containing one or more isoflavones, and their ability to affect changes in mammalian hair growth, hair follicle and hair shaft size and hair pigmentation.

Claims (52)

1. A method for effecting changes in mammalian hair appearance, heir growth, hair pigmentation and hair follicle and hair shaft size, comprising topical application to the skin of a mammal an effective amount of a topically active composition comprising one or more compounds derived from one or more of the botanical families leguminosae, solanaceae, gramineae and cucurbitaceae.
2. The method of claim 1 wherein said extract contains at least one serine protease inhibitory activity.
3. The method of claim 2 wherein said at least one serine protease inhibitory active agent is a serine protease inhibitor.
4. The method of claim 3 wherein said at least one serine protease inhibitor is present in an amount, based upon the total volume of the topically active composition, of from about 0.0001% (w/v) to 20% (w/v).
5. The method of claim 4 wherein the at least one serine protease inhibitor is present in an amount, based upon the total volume of the topically active composition, of from about 0.001 (w/v) to about 5%
(w/v).
6. The method of claim 1 wherein one of said changes is a delay in hair growth, reduced hair follicle and hair shaft size and reduced hair pigmentation.
7. The method of claim 1 wherein said topically active composition further comprises a pharmaceutically or cosmetically acceptable vehicle.
8. The method of claim 1 wherein said topically active composition further comprises one or more isoflavones.
9. The method of claim 8 wherein said topically active composition further comprises a pharmaceutically or cosmetically acceptable vehicle.
10. The method of claim 1 wherein said typically active composition further comprises natural extracts containing one or more isoflavones.
11. The method of claim 1 wherein said composition is applied topically in conjunction with one or more products whose purpose is to either facilitate the removal of hair or actually remove hair or reduce hair visibility or improve hair style or improve hair management.
12. The method of claim 1 wherein said composition is applied topically before or following hair removal.
13. The method of claim 1 wherein said composition is applied topically during hair removal.
14. The method of claim 1 wherein said composition is applied topically in conjunction with one or more of the group consisting of: depilatory agents, shampoo, hair conditioner, styling gel, hair care products, waxing products, shaving products, hair-removal products, after-shave products, deodorant, anti-perspirant, electrolysis, laser hair removal, light-induced hair removal, mask, bath additives.
15. The method of claim 1 further comprising leaving said composition on raid skin for a period sufficient to effect said changes.
16. The method of claim 1 wherein said period is daily treatment for at least about four weeks.
17. A method according to claim 16 wherein said composition is applied daily for at least eight weeks.
18. A method according to claim 1 wherein said composition is applied daily to reduce or prevent pseudofolliculitis barbae.
19. A method according to claim 1 wherein said composition is applied daily to the axilliary area to reduce hair growth.
20. A method according to claim 1 wherein said composition is applied daily to the scalp to style and improve management of African type hair.
21. A method according to claim 1 wherein said composition is added daily to a bath.
22. A method according to claim 1 wherein said composition is used daily on facial or body parts for delaying hair growth and reducing hair visibility in sufferers of hirsutism.
23. A composition for affecting changes in mammalian hair growth, hair pigmentation and hair shaft and follicle size, comprising topically applying to skin of a mammal an effective amount of a topically active composition comprising one or more compounds derived from one or more of the botanical families leguminosae, solanaceae, gramineae and cucurbitaceae.
24. The composition of claim 23 wherein the extract contains at least one serine protease inhibitory activity.
25. The composition of claim 24 wherein the at least one serine protease inhibitory active agent is present in an amount, based upon the total volume of the topically active composition, of from about 0.0001%
(w/v) to about 20% (w/v).
26. The composition of claim 25 wherein the at least one protease inhibitory active agent is present in an amount, based upon the total volume of the topically active composition, of from about 0.001% (w/v) to about 5% (w/v).
27. The composition of claim 23 wherein the composition further comprises one or more isoflavones.
28. The composition of claim 23 wherein the composition further comprises one or more natural extracts containing one or more isoflavones.
29. The composition of claim 23 wherein the composition further comprises surfactants, moisturizers, humectants, foaming agents, cosmetic adjuvants, buffering agents, preservatives, anti-oxidants, conditioners, depigmenting agents, hair removal agents, anti-aging agents, sunscreens, fragrances, colorants, or mixtures thereof.
30. The composition of claim 23 wherein said composition is in the form of liquid, cream, gel, paste, powder, essence, mousse, emulsion, film patch or spray.
31. The composition of claim 23 wherein said composition further comprises one or more products whose purpose is to either facilitate the removal of hair or actually remove hair or reduce hair visibility or improve hair management.
32. The composition of claim 23 wherein said composition further comprises one or more of the group consisting of depilatory cream, shampoo, hair conditioner, styling gel, hair care products, waxing products, shaving products, hair removal products, after-shave products, deodorant, anti-perspirant, pre- or post -electrolysis products, pre- or post-laser hair removal products, pre- or post-light-induced hair removal products, mask, bath additives.
33. A composition according to claim 23 wherein said compound is derived from legumes.
34. A composition according to claim 33 wherein said compound is derived from say, lima and/or black beans.
35. A composition according to claim 34 wherein said compound is selected from the group consisting of soybean milk, limabean milk, blackbean milk, soybean extract, limabean extract, blackbean extract, soybean paste, limabean paste, blackbean paste, soybean powder, blackbean powder, limabean powder, soymilk powder, blackbean milk powder and limabean milk powder and mixtures thereof.
36. A composition according to claim 35 wherein said compound is a fraction of soybean milk, soybean extract, soybean paste, limabean milk, limabean extract, limabean paste, blackbean milk, blackbean extract, blackbean paste, soybean powder, blackbean powder, limabean powder, soymilk powder, blackbean milk powder and limabean milk powder and mixtures thereof.
37. A composition according to claim 35 comprising bean milk in an amount of from about 1 to about 99% by weight.
38. A composition according to claim 35 comprising soybean powder, soymilk powder or a mixture thereof in an amount of from about 1 to about 99% by weight.
39. A composition according to claim 36 comprising soybean trypsin inhibitor, limabean trypsin inhibitor or blackbean trypsin inhibitor in an amount of from about 0.0001 to about 20% by weight.
40. A composition according to claim 33 said composition further comprising one or more isoflavones.
41. A composition according to claim 33 said composition further comprising one or more natural extracts containing one or more isoflavones.
42. A composition according to claim 40 wherein said one or more isoflavones are present in said composition in amount of from about 0.00001 to about 0.1 % by weight.
43. A composition according to claim 41 wherein said one or more natural extract containing said one or more isoflavones are present in said composition in amount of from about 0.00001 to about 0.1 % by weight.
44. A cosmetic composition according to claim 23, said composition further comprising a cosmetically-acceptable vehicle.
45. A composition according to claim 23 wherein said composition further comprises liposomes.
46. A composition according to claim 45 wherein said composition comprises glycerol dilaurate, cholesterol, polyoxyethylene-10-stearyl ether and polyoxyethylene-9-lauryl ether.
47. A composition according to claim 23 wherein said composition comprises from about 1 to about 99% bean milk, from about 0.1 to about 20% emulsifier and preservatives in an effective amount.
48. A composition according to claim 23 wherein said composition comprises from about 0.5 to about 20 %

soybean powder or soymilk powder, from about 0.1 to about 20% emulsifier and preservatives in an effective amount.
49. A composition according to claim 47 wherein said composition further comprises one or more isoflavones in an amount of from about 0.00001 to about 0.1%.
50. A composition according to claim 47 wherein said composition further comprises one or more natural extracts comprising one ar more isoflavones in an amount of from about 0.0001 to about 0.1%.
51. A composition according to claim 23 wherein said composition further comprises one or more isoflavones in an amount of from about 0.0001 to about 0.1 %.
52. A composition according to claim 48 wherein said composition further comprises one or mare natural extracts comprising one or more isoflavones in an amount of from about 0.0005 to about 0.05 %.
CA2314562A 1999-07-27 2000-07-26 Reducing hair growth, hair follicle and hair shaft size and hair pigmentation Expired - Fee Related CA2314562C (en)

Applications Claiming Priority (4)

Application Number Priority Date Filing Date Title
US14577499P 1999-07-27 1999-07-27
US60/145,774 1999-07-27
US09/621,565 2000-07-21
US09/621,565 US7985404B1 (en) 1999-07-27 2000-07-21 Reducing hair growth, hair follicle and hair shaft size and hair pigmentation

Publications (2)

Publication Number Publication Date
CA2314562A1 true CA2314562A1 (en) 2001-01-27
CA2314562C CA2314562C (en) 2011-08-23

Family

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Family Applications (1)

Application Number Title Priority Date Filing Date
CA2314562A Expired - Fee Related CA2314562C (en) 1999-07-27 2000-07-26 Reducing hair growth, hair follicle and hair shaft size and hair pigmentation

Country Status (10)

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US (3) US7985404B1 (en)
EP (1) EP1074240B1 (en)
JP (1) JP2001072555A (en)
KR (1) KR20010015444A (en)
CN (1) CN100337685C (en)
AT (1) ATE474551T1 (en)
CA (1) CA2314562C (en)
DE (1) DE60044697D1 (en)
ES (1) ES2347316T3 (en)
HK (1) HK1032540A1 (en)

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HK1032540A1 (en) 2001-07-27
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