CA2337197A1 - Microdevices for screening biomolecules - Google Patents

Microdevices for screening biomolecules Download PDF

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Publication number
CA2337197A1
CA2337197A1 CA002337197A CA2337197A CA2337197A1 CA 2337197 A1 CA2337197 A1 CA 2337197A1 CA 002337197 A CA002337197 A CA 002337197A CA 2337197 A CA2337197 A CA 2337197A CA 2337197 A1 CA2337197 A1 CA 2337197A1
Authority
CA
Canada
Prior art keywords
devices
screening
microdevices
parallel
biomolecules
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Granted
Application number
CA002337197A
Other languages
French (fr)
Other versions
CA2337197C (en
Inventor
Peter Wagner
Dana Ault-Riche
Steffen Nock
Christian Itin
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Zyomyx Inc
Original Assignee
Zyomyx, Inc.
Peter Wagner
Dana Ault-Riche
Steffen Nock
Christian Itin
Advanced Biointegrated Technologies, Inc.
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Zyomyx, Inc., Peter Wagner, Dana Ault-Riche, Steffen Nock, Christian Itin, Advanced Biointegrated Technologies, Inc. filed Critical Zyomyx, Inc.
Publication of CA2337197A1 publication Critical patent/CA2337197A1/en
Application granted granted Critical
Publication of CA2337197C publication Critical patent/CA2337197C/en
Anticipated expiration legal-status Critical
Expired - Fee Related legal-status Critical Current

Links

Classifications

    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B82—NANOTECHNOLOGY
    • B82Y—SPECIFIC USES OR APPLICATIONS OF NANOSTRUCTURES; MEASUREMENT OR ANALYSIS OF NANOSTRUCTURES; MANUFACTURE OR TREATMENT OF NANOSTRUCTURES
    • B82Y30/00—Nanotechnology for materials or surface science, e.g. nanocomposites
    • Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10—TECHNICAL SUBJECTS COVERED BY FORMER USPC
    • Y10S—TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10S435/00—Chemistry: molecular biology and microbiology
    • Y10S435/805—Test papers
    • Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10—TECHNICAL SUBJECTS COVERED BY FORMER USPC
    • Y10S—TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10S435/00—Chemistry: molecular biology and microbiology
    • Y10S435/81—Packaged device or kit
    • Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10—TECHNICAL SUBJECTS COVERED BY FORMER USPC
    • Y10T—TECHNICAL SUBJECTS COVERED BY FORMER US CLASSIFICATION
    • Y10T436/00—Chemistry: analytical and immunological testing
    • Y10T436/14—Heterocyclic carbon compound [i.e., O, S, N, Se, Te, as only ring hetero atom]
    • Y10T436/142222—Hetero-O [e.g., ascorbic acid, etc.]
    • Y10T436/143333—Saccharide [e.g., DNA, etc.]

Abstract

Methods and devices for the parallel, in vitro screening of biomolecular activity using miniaturized microfabricated devices are provided. The biomolecules immobilized on the surface of the devices of the present invention include proteins, polypeptides, polynucleotides, polysaccharides, phospholipids, and related unnatural polymers of biological relevance. These devices are useful in drug development, functional proteomics and clinical diagnostics and are preferably used for the parallel screening of families of related proteins.
CA002337197A 1998-07-14 1999-07-14 Microdevices for screening biomolecules Expired - Fee Related CA2337197C (en)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US09/115,397 US6576478B1 (en) 1998-07-14 1998-07-14 Microdevices for high-throughput screening of biomolecules
US09/115,397 1998-07-14
PCT/US1999/015969 WO2000004390A2 (en) 1998-07-14 1999-07-14 Microdevices for screening biomolecules

Publications (2)

Publication Number Publication Date
CA2337197A1 true CA2337197A1 (en) 2000-01-27
CA2337197C CA2337197C (en) 2007-09-18

Family

ID=22361123

Family Applications (1)

Application Number Title Priority Date Filing Date
CA002337197A Expired - Fee Related CA2337197C (en) 1998-07-14 1999-07-14 Microdevices for screening biomolecules

Country Status (8)

Country Link
US (6) US6576478B1 (en)
EP (1) EP1097379B1 (en)
JP (1) JP4489949B2 (en)
AT (1) ATE419527T1 (en)
AU (1) AU764027B2 (en)
CA (1) CA2337197C (en)
DE (1) DE69940198D1 (en)
WO (1) WO2000004390A2 (en)

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US6576478B1 (en) 2003-06-10
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US6596545B1 (en) 2003-07-22
EP1097379A2 (en) 2001-05-09
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US20020115225A1 (en) 2002-08-22
AU764027B2 (en) 2003-08-07

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