CA2339353A1 - Fast dissolving orally consumable films - Google Patents

Fast dissolving orally consumable films Download PDF

Info

Publication number
CA2339353A1
CA2339353A1 CA002339353A CA2339353A CA2339353A1 CA 2339353 A1 CA2339353 A1 CA 2339353A1 CA 002339353 A CA002339353 A CA 002339353A CA 2339353 A CA2339353 A CA 2339353A CA 2339353 A1 CA2339353 A1 CA 2339353A1
Authority
CA
Canada
Prior art keywords
films
disclosed
fast dissolving
orally consumable
pullulan
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Granted
Application number
CA002339353A
Other languages
French (fr)
Other versions
CA2339353C (en
Inventor
Sau-Hung Spence Leung
Robert S. Leone
Lori Dee Kumar
Neema Kulkarni
Albert F. Sorg
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Warner Lambert Co LLC
Original Assignee
Warner-Lambert Company
Sau-Hung Spence Leung
Robert S. Leone
Lori Dee Kumar
Neema Kulkarni
Albert F. Sorg
Warner-Lambert Company Llc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Warner-Lambert Company, Sau-Hung Spence Leung, Robert S. Leone, Lori Dee Kumar, Neema Kulkarni, Albert F. Sorg, Warner-Lambert Company Llc filed Critical Warner-Lambert Company
Priority to CA002520986A priority Critical patent/CA2520986C/en
Publication of CA2339353A1 publication Critical patent/CA2339353A1/en
Application granted granted Critical
Publication of CA2339353C publication Critical patent/CA2339353C/en
Anticipated expiration legal-status Critical
Expired - Lifetime legal-status Critical Current

Links

Classifications

    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00Medicinal preparations characterised by special physical form
    • A61K9/70Web, sheet or filament bases ; Films; Fibres of the matrix type containing drug
    • AHUMAN NECESSITIES
    • A23FOODS OR FOODSTUFFS; TREATMENT THEREOF, NOT COVERED BY OTHER CLASSES
    • A23GCOCOA; COCOA PRODUCTS, e.g. CHOCOLATE; SUBSTITUTES FOR COCOA OR COCOA PRODUCTS; CONFECTIONERY; CHEWING GUM; ICE-CREAM; PREPARATION THEREOF
    • A23G3/00Sweetmeats; Confectionery; Marzipan; Coated or filled products
    • A23G3/34Sweetmeats, confectionery or marzipan; Processes for the preparation thereof
    • A23G3/50Sweetmeats, confectionery or marzipan; Processes for the preparation thereof characterised by shape, structure or physical form, e.g. products with supported structure
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K8/00Cosmetics or similar toiletry preparations
    • A61K8/02Cosmetics or similar toiletry preparations characterised by special physical form
    • A61K8/0208Tissues; Wipes; Patches
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K8/00Cosmetics or similar toiletry preparations
    • A61K8/02Cosmetics or similar toiletry preparations characterised by special physical form
    • A61K8/0216Solid or semisolid forms
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K8/00Cosmetics or similar toiletry preparations
    • A61K8/18Cosmetics or similar toiletry preparations characterised by the composition
    • A61K8/19Cosmetics or similar toiletry preparations characterised by the composition containing inorganic ingredients
    • A61K8/20Halogens; Compounds thereof
    • A61K8/21Fluorides; Derivatives thereof
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K8/00Cosmetics or similar toiletry preparations
    • A61K8/18Cosmetics or similar toiletry preparations characterised by the composition
    • A61K8/30Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds
    • A61K8/33Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds containing oxygen
    • A61K8/34Alcohols
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K8/00Cosmetics or similar toiletry preparations
    • A61K8/18Cosmetics or similar toiletry preparations characterised by the composition
    • A61K8/30Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds
    • A61K8/33Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds containing oxygen
    • A61K8/34Alcohols
    • A61K8/347Phenols
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K8/00Cosmetics or similar toiletry preparations
    • A61K8/18Cosmetics or similar toiletry preparations characterised by the composition
    • A61K8/30Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds
    • A61K8/33Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds containing oxygen
    • A61K8/37Esters of carboxylic acids
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K8/00Cosmetics or similar toiletry preparations
    • A61K8/18Cosmetics or similar toiletry preparations characterised by the composition
    • A61K8/30Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds
    • A61K8/40Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds containing nitrogen
    • A61K8/41Amines
    • A61K8/416Quaternary ammonium compounds
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K8/00Cosmetics or similar toiletry preparations
    • A61K8/18Cosmetics or similar toiletry preparations characterised by the composition
    • A61K8/30Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds
    • A61K8/40Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds containing nitrogen
    • A61K8/43Guanidines
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K8/00Cosmetics or similar toiletry preparations
    • A61K8/18Cosmetics or similar toiletry preparations characterised by the composition
    • A61K8/30Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds
    • A61K8/40Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds containing nitrogen
    • A61K8/44Aminocarboxylic acids or derivatives thereof, e.g. aminocarboxylic acids containing sulfur; Salts; Esters or N-acylated derivatives thereof
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K8/00Cosmetics or similar toiletry preparations
    • A61K8/18Cosmetics or similar toiletry preparations characterised by the composition
    • A61K8/30Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds
    • A61K8/49Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds containing heterocyclic compounds
    • A61K8/4973Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds containing heterocyclic compounds with oxygen as the only hetero atom
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K8/00Cosmetics or similar toiletry preparations
    • A61K8/18Cosmetics or similar toiletry preparations characterised by the composition
    • A61K8/30Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds
    • A61K8/64Proteins; Peptides; Derivatives or degradation products thereof
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K8/00Cosmetics or similar toiletry preparations
    • A61K8/18Cosmetics or similar toiletry preparations characterised by the composition
    • A61K8/30Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds
    • A61K8/64Proteins; Peptides; Derivatives or degradation products thereof
    • A61K8/645Proteins of vegetable origin; Derivatives or degradation products thereof
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K8/00Cosmetics or similar toiletry preparations
    • A61K8/18Cosmetics or similar toiletry preparations characterised by the composition
    • A61K8/30Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds
    • A61K8/64Proteins; Peptides; Derivatives or degradation products thereof
    • A61K8/65Collagen; Gelatin; Keratin; Derivatives or degradation products thereof
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K8/00Cosmetics or similar toiletry preparations
    • A61K8/18Cosmetics or similar toiletry preparations characterised by the composition
    • A61K8/72Cosmetics or similar toiletry preparations characterised by the composition containing organic macromolecular compounds
    • A61K8/73Polysaccharides
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K8/00Cosmetics or similar toiletry preparations
    • A61K8/18Cosmetics or similar toiletry preparations characterised by the composition
    • A61K8/72Cosmetics or similar toiletry preparations characterised by the composition containing organic macromolecular compounds
    • A61K8/73Polysaccharides
    • A61K8/731Cellulose; Quaternized cellulose derivatives
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K8/00Cosmetics or similar toiletry preparations
    • A61K8/18Cosmetics or similar toiletry preparations characterised by the composition
    • A61K8/72Cosmetics or similar toiletry preparations characterised by the composition containing organic macromolecular compounds
    • A61K8/73Polysaccharides
    • A61K8/732Starch; Amylose; Amylopectin; Derivatives thereof
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K8/00Cosmetics or similar toiletry preparations
    • A61K8/18Cosmetics or similar toiletry preparations characterised by the composition
    • A61K8/72Cosmetics or similar toiletry preparations characterised by the composition containing organic macromolecular compounds
    • A61K8/73Polysaccharides
    • A61K8/733Alginic acid; Salts thereof
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K8/00Cosmetics or similar toiletry preparations
    • A61K8/18Cosmetics or similar toiletry preparations characterised by the composition
    • A61K8/72Cosmetics or similar toiletry preparations characterised by the composition containing organic macromolecular compounds
    • A61K8/73Polysaccharides
    • A61K8/736Chitin; Chitosan; Derivatives thereof
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K8/00Cosmetics or similar toiletry preparations
    • A61K8/18Cosmetics or similar toiletry preparations characterised by the composition
    • A61K8/72Cosmetics or similar toiletry preparations characterised by the composition containing organic macromolecular compounds
    • A61K8/81Cosmetics or similar toiletry preparations characterised by the composition containing organic macromolecular compounds obtained by reactions involving only carbon-to-carbon unsaturated bonds
    • A61K8/8129Compositions of homopolymers or copolymers of compounds having one or more unsaturated aliphatic radicals, each having only one carbon-to-carbon double bond, and at least one being terminated by an alcohol, ether, aldehydo, ketonic, acetal or ketal radical; Compositions of hydrolysed polymers or esters of unsaturated alcohols with saturated carboxylic acids; Compositions of derivatives of such polymers, e.g. polyvinylmethylether
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K8/00Cosmetics or similar toiletry preparations
    • A61K8/18Cosmetics or similar toiletry preparations characterised by the composition
    • A61K8/72Cosmetics or similar toiletry preparations characterised by the composition containing organic macromolecular compounds
    • A61K8/81Cosmetics or similar toiletry preparations characterised by the composition containing organic macromolecular compounds obtained by reactions involving only carbon-to-carbon unsaturated bonds
    • A61K8/8141Compositions of homopolymers or copolymers of compounds having one or more unsaturated aliphatic radicals, each having only one carbon-to-carbon double bond, and at least one being terminated by only one carboxyl radical, or of salts, anhydrides, esters, amides, imides or nitriles thereof; Compositions of derivatives of such polymers
    • A61K8/8147Homopolymers or copolymers of acids; Metal or ammonium salts thereof, e.g. crotonic acid, (meth)acrylic acid; Compositions of derivatives of such polymers
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K8/00Cosmetics or similar toiletry preparations
    • A61K8/18Cosmetics or similar toiletry preparations characterised by the composition
    • A61K8/72Cosmetics or similar toiletry preparations characterised by the composition containing organic macromolecular compounds
    • A61K8/81Cosmetics or similar toiletry preparations characterised by the composition containing organic macromolecular compounds obtained by reactions involving only carbon-to-carbon unsaturated bonds
    • A61K8/8141Compositions of homopolymers or copolymers of compounds having one or more unsaturated aliphatic radicals, each having only one carbon-to-carbon double bond, and at least one being terminated by only one carboxyl radical, or of salts, anhydrides, esters, amides, imides or nitriles thereof; Compositions of derivatives of such polymers
    • A61K8/8152Homopolymers or copolymers of esters, e.g. (meth)acrylic acid esters; Compositions of derivatives of such polymers
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K8/00Cosmetics or similar toiletry preparations
    • A61K8/18Cosmetics or similar toiletry preparations characterised by the composition
    • A61K8/72Cosmetics or similar toiletry preparations characterised by the composition containing organic macromolecular compounds
    • A61K8/81Cosmetics or similar toiletry preparations characterised by the composition containing organic macromolecular compounds obtained by reactions involving only carbon-to-carbon unsaturated bonds
    • A61K8/817Compositions of homopolymers or copolymers of compounds having one or more unsaturated aliphatic radicals, each having only one carbon-to-carbon double bond, and at least one being terminated by a single or double bond to nitrogen or by a heterocyclic ring containing nitrogen; Compositions or derivatives of such polymers, e.g. vinylimidazol, vinylcaprolactame, allylamines (Polyquaternium 6)
    • A61K8/8176Homopolymers of N-vinyl-pyrrolidones. Compositions of derivatives of such polymers
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K8/00Cosmetics or similar toiletry preparations
    • A61K8/18Cosmetics or similar toiletry preparations characterised by the composition
    • A61K8/72Cosmetics or similar toiletry preparations characterised by the composition containing organic macromolecular compounds
    • A61K8/84Cosmetics or similar toiletry preparations characterised by the composition containing organic macromolecular compounds obtained by reactions otherwise than those involving only carbon-carbon unsaturated bonds
    • A61K8/86Polyethers
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K8/00Cosmetics or similar toiletry preparations
    • A61K8/18Cosmetics or similar toiletry preparations characterised by the composition
    • A61K8/92Oils, fats or waxes; Derivatives thereof, e.g. hydrogenation products thereof
    • A61K8/922Oils, fats or waxes; Derivatives thereof, e.g. hydrogenation products thereof of vegetable origin
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00Medicinal preparations characterised by special physical form
    • A61K9/0012Galenical forms characterised by the site of application
    • A61K9/0053Mouth and digestive tract, i.e. intraoral and peroral administration
    • A61K9/0056Mouth soluble or dispersible forms; Suckable, eatable, chewable coherent forms; Forms rapidly disintegrating in the mouth; Lozenges; Lollipops; Bite capsules; Baked products; Baits or other oral forms for animals
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00Medicinal preparations characterised by special physical form
    • A61K9/0012Galenical forms characterised by the site of application
    • A61K9/0053Mouth and digestive tract, i.e. intraoral and peroral administration
    • A61K9/006Oral mucosa, e.g. mucoadhesive forms, sublingual droplets; Buccal patches or films; Buccal sprays
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00Medicinal preparations characterised by special physical form
    • A61K9/70Web, sheet or filament bases ; Films; Fibres of the matrix type containing drug
    • A61K9/7007Drug-containing films, membranes or sheets
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P1/00Drugs for disorders of the alimentary tract or the digestive system
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P1/00Drugs for disorders of the alimentary tract or the digestive system
    • A61P1/02Stomatological preparations, e.g. drugs for caries, aphtae, periodontitis
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P1/00Drugs for disorders of the alimentary tract or the digestive system
    • A61P1/04Drugs for disorders of the alimentary tract or the digestive system for ulcers, gastritis or reflux esophagitis, e.g. antacids, inhibitors of acid secretion, mucosal protectants
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P1/00Drugs for disorders of the alimentary tract or the digestive system
    • A61P1/12Antidiarrhoeals
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P11/00Drugs for disorders of the respiratory system
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P11/00Drugs for disorders of the respiratory system
    • A61P11/10Expectorants
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P11/00Drugs for disorders of the respiratory system
    • A61P11/14Antitussive agents
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00Drugs for disorders of the nervous system
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00Drugs for disorders of the nervous system
    • A61P25/04Centrally acting analgesics, e.g. opioids
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P29/00Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/04Antibacterial agents
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P37/00Drugs for immunological or allergic disorders
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61QSPECIFIC USE OF COSMETICS OR SIMILAR TOILETRY PREPARATIONS
    • A61Q11/00Preparations for care of the teeth, of the oral cavity or of dentures; Dentifrices, e.g. toothpastes; Mouth rinses
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00Medicinal preparations characterised by special physical form
    • A61K9/20Pills, tablets, discs, rods
    • A61K9/2072Pills, tablets, discs, rods characterised by shape, structure or size; Tablets with holes, special break lines or identification marks; Partially coated tablets; Disintegrating flat shaped forms

Abstract

Physiologically acceptable films, including edible films, are disclosed. The films include a water soluble film-forming polymer such as pullulan. Edible films are disclosed that include pullulan and antimicrobially effective amounts of the essential oils thymol, methyl salicylate, eucalyptol and menthol. The edible films are effective at killing the plaque-producing germs that cause dental plaque, gingivitis and bad breath. The film can also contain pharmaceutically acitve agents.
Methods for producing the films are also disclosed.
CA002339353A 1998-09-25 1999-09-23 Fast dissolving orally consumable films Expired - Lifetime CA2339353C (en)

Priority Applications (1)

Application Number Priority Date Filing Date Title
CA002520986A CA2520986C (en) 1998-09-25 1999-09-23 Physiological compatible film

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US10179898P 1998-09-25 1998-09-25
US60/101,798 1998-09-25
PCT/US1999/022115 WO2000018365A2 (en) 1998-09-25 1999-09-23 Fast dissolving orally consumable films

Related Child Applications (1)

Application Number Title Priority Date Filing Date
CA002520986A Division CA2520986C (en) 1998-09-25 1999-09-23 Physiological compatible film

Publications (2)

Publication Number Publication Date
CA2339353A1 true CA2339353A1 (en) 2000-04-06
CA2339353C CA2339353C (en) 2006-01-24

Family

ID=22286467

Family Applications (1)

Application Number Title Priority Date Filing Date
CA002339353A Expired - Lifetime CA2339353C (en) 1998-09-25 1999-09-23 Fast dissolving orally consumable films

Country Status (29)

Country Link
US (8) US6596298B2 (en)
EP (2) EP1115372B1 (en)
JP (1) JP2002525306A (en)
KR (1) KR20010075347A (en)
CN (2) CN1321080A (en)
AR (2) AR020513A1 (en)
AT (1) ATE326203T1 (en)
AU (1) AU771862B2 (en)
BR (2) BR9917781B1 (en)
CA (1) CA2339353C (en)
CO (2) CO4940396A1 (en)
CY (1) CY1105213T1 (en)
DE (1) DE69931380T2 (en)
DK (1) DK1115372T3 (en)
EE (1) EE200100186A (en)
ES (1) ES2260961T3 (en)
GT (2) GT199900164A (en)
HK (1) HK1040619A1 (en)
ID (1) ID27740A (en)
IL (2) IL141919A0 (en)
NO (1) NO20011476D0 (en)
PA (1) PA8482401A1 (en)
PE (1) PE20000972A1 (en)
PT (1) PT1115372E (en)
SI (1) SI1115372T1 (en)
TW (2) TWI238067B (en)
UY (1) UY25728A1 (en)
WO (1) WO2000018365A2 (en)
ZA (1) ZA200101706B (en)

Cited By (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO2022140841A1 (en) * 2020-12-28 2022-07-07 Psilo Scientific Ltd Transmucosal psychoactive alkaloid composition and preparation thereof
US11571450B2 (en) 2020-06-17 2023-02-07 Psilo Scientific Ltd Aqueous extraction of psychoactive compounds from psilocybin fungus

Families Citing this family (517)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US20030211136A1 (en) * 1998-09-25 2003-11-13 Neema Kulkarni Fast dissolving orally consumable films containing a sweetener
US20030206942A1 (en) 1998-09-25 2003-11-06 Neema Kulkarni Fast dissolving orally consumable films containing an antitussive and a mucosa coating agent
US6596298B2 (en) * 1998-09-25 2003-07-22 Warner-Lambert Company Fast dissolving orally comsumable films
CA2356533C (en) 1998-12-23 2010-07-13 Mount Sinai School Of Medicine Inhibitors of the bitter taste response
US20040115252A1 (en) * 1999-06-25 2004-06-17 Thomas Leon Methods of treating illnesses in non-human mammals
PL200936B1 (en) 1999-07-02 2009-02-27 Procter & Gamble Delivery system for oral care compositions comprising organosiloxane reins using a removable backing strip
DK1204699T3 (en) * 1999-07-22 2005-08-15 Warner Lambert Co Film compositions of pullulan
US7314716B2 (en) * 1999-11-19 2008-01-01 Mount Sinai School Of Medicine Gustducin γ subunit materials and methods
US7067116B1 (en) * 2000-03-23 2006-06-27 Warner-Lambert Company Llc Fast dissolving orally consumable solid film containing a taste masking agent and pharmaceutically active agent at weight ratio of 1:3 to 3:1
US6315987B1 (en) * 2000-05-10 2001-11-13 Isp Investments Inc. Polymeric delivery and release systems for oral care actives
DE10032456A1 (en) 2000-07-04 2002-01-31 Lohmann Therapie Syst Lts Rapidly disintegrating dosage form for the release of active substances in the mouth or in the body cavities
USRE44145E1 (en) 2000-07-07 2013-04-09 A.V. Topchiev Institute Of Petrochemical Synthesis Preparation of hydrophilic pressure sensitive adhesives having optimized adhesive properties
US6391886B1 (en) * 2000-12-04 2002-05-21 The Procter & Gamble Company Oral compositions having improved consumer aesthetics
DE10063945A1 (en) * 2000-12-20 2002-07-04 Henkel Kgaa Remineralizing dental adhesive film
US20040043013A1 (en) 2000-12-28 2004-03-04 Mccleary Edward Larry Metabolic uncoupling therapy
US20060062864A1 (en) * 2000-12-28 2006-03-23 Mccleary Edward L Weight loss composition and method
EP1370206A4 (en) * 2001-01-09 2006-04-05 Lavipharm Lab Inc Devices for local and systemic delivery of active substances and methods of manufacturing thereof
PL364571A1 (en) 2001-01-23 2004-12-13 Dusan Ninkov Pesticidal compounds and compositions
DE10107659B4 (en) * 2001-02-19 2008-03-13 Lts Lohmann Therapie-Systeme Ag Mucoadhesive disintegratable drug preparation for drug administration in veterinary and human medicine
EP1236466B1 (en) * 2001-02-28 2011-09-21 Axiomedic Ltd. Solid self-adhesive compositions for topical treatment of oral mucosal disorders
US8980334B2 (en) 2001-02-28 2015-03-17 Axiomedic Ltd. Double-layered absorbable solid compositions for the topical treatment of oral mucosal disorders
US20060014773A1 (en) * 2001-04-19 2006-01-19 Mccleary Edward L Mental agility lozenge, edible strip, food or drink
US20060110478A1 (en) * 2004-11-22 2006-05-25 Mccleary Edward L Delivery system and method for supporting and promoting healthy sexual function and prevention and treatment of sexual dysfunction
US20050113510A1 (en) 2001-05-01 2005-05-26 Feldstein Mikhail M. Method of preparing polymeric adhesive compositions utilizing the mechanism of interaction between the polymer components
EP1390085B1 (en) 2001-05-01 2009-08-05 A.V. Topchiev Institute of Petrochemical Synthesis Hydrogel compositions
US8541021B2 (en) 2001-05-01 2013-09-24 A.V. Topchiev Institute Of Petrochemical Synthesis Hydrogel compositions demonstrating phase separation on contact with aqueous media
EP1390084B1 (en) 2001-05-01 2011-03-23 A.V. Topchiev Institute of Petrochemical Synthesis Two-phase, water-absorbent bioadhesive composition
US8840918B2 (en) 2001-05-01 2014-09-23 A. V. Topchiev Institute of Petrochemical Synthesis, Russian Academy of Sciences Hydrogel compositions for tooth whitening
US20050215727A1 (en) 2001-05-01 2005-09-29 Corium Water-absorbent adhesive compositions and associated methods of manufacture and use
US8206738B2 (en) 2001-05-01 2012-06-26 Corium International, Inc. Hydrogel compositions with an erodible backing member
US6976647B2 (en) * 2001-06-05 2005-12-20 Elan Pharma International, Limited System and method for milling materials
US6660292B2 (en) * 2001-06-19 2003-12-09 Hf Flavoring Technology Llp Rapidly disintegrating flavored film for precooked foods
US6656493B2 (en) 2001-07-30 2003-12-02 Wm. Wrigley Jr. Company Edible film formulations containing maltodextrin
US6419903B1 (en) * 2001-08-20 2002-07-16 Colgate Palmolive Company Breath freshening film
JP5089840B2 (en) * 2001-09-25 2012-12-05 救急薬品工業株式会社 Nicotine-containing film preparation
ES2344407T3 (en) * 2001-10-09 2010-08-26 Arrow Coated Products Limited MANUFACTURING PROCEDURE OF A SOLUBLE FILM SYSTEM IN EMBEDDED WATER.
US20070154527A1 (en) * 2001-10-12 2007-07-05 Monosoirx, Llc Topical film compositions for delivery of actives
US7910641B2 (en) * 2001-10-12 2011-03-22 Monosol Rx, Llc PH modulated films for delivery of actives
US8663687B2 (en) 2001-10-12 2014-03-04 Monosol Rx, Llc Film compositions for delivery of actives
US7357891B2 (en) 2001-10-12 2008-04-15 Monosol Rx, Llc Process for making an ingestible film
US20070281003A1 (en) 2001-10-12 2007-12-06 Fuisz Richard C Polymer-Based Films and Drug Delivery Systems Made Therefrom
US10285910B2 (en) 2001-10-12 2019-05-14 Aquestive Therapeutics, Inc. Sublingual and buccal film compositions
US8765167B2 (en) * 2001-10-12 2014-07-01 Monosol Rx, Llc Uniform films for rapid-dissolve dosage form incorporating anti-tacking compositions
US20060039958A1 (en) * 2003-05-28 2006-02-23 Monosolrx, Llc. Multi-layer films having uniform content
US8603514B2 (en) 2002-04-11 2013-12-10 Monosol Rx, Llc Uniform films for rapid dissolve dosage form incorporating taste-masking compositions
US8900498B2 (en) 2001-10-12 2014-12-02 Monosol Rx, Llc Process for manufacturing a resulting multi-layer pharmaceutical film
US20110033542A1 (en) 2009-08-07 2011-02-10 Monosol Rx, Llc Sublingual and buccal film compositions
US11207805B2 (en) 2001-10-12 2021-12-28 Aquestive Therapeutics, Inc. Process for manufacturing a resulting pharmaceutical film
US20100021526A1 (en) * 2001-10-12 2010-01-28 Monosol Rx, Llc Ph modulated films for delivery of actives
US8900497B2 (en) 2001-10-12 2014-12-02 Monosol Rx, Llc Process for making a film having a substantially uniform distribution of components
CA2473975C (en) * 2001-10-12 2011-05-03 Monosolrx Llc Glucan based film delivery systems
US7425292B2 (en) * 2001-10-12 2008-09-16 Monosol Rx, Llc Thin film with non-self-aggregating uniform heterogeneity and drug delivery systems made therefrom
US7666337B2 (en) 2002-04-11 2010-02-23 Monosol Rx, Llc Polyethylene oxide-based films and drug delivery systems made therefrom
US20190328679A1 (en) 2001-10-12 2019-10-31 Aquestive Therapeutics, Inc. Uniform films for rapid-dissolve dosage form incorporating anti-tacking compositions
US20030099691A1 (en) * 2001-11-16 2003-05-29 Susan Lydzinski Films containing starch
GB0128674D0 (en) * 2001-11-30 2002-01-23 Boots Co Plc Treatment of sleep disorders and the like
EP1790687A3 (en) * 2001-12-11 2007-07-25 Ceapro Inc. Cereal beta glucan compositions, methods of preparation and uses thereof
ATE374796T1 (en) * 2001-12-11 2007-10-15 Ceapro Inc COMPOSITIONS BASED ON BETA GLUCAN FROM CEREALS, METHOD OF PRODUCTION AND USES
KR20030054221A (en) * 2001-12-24 2003-07-02 애경산업(주) Composite film composition for oral cavity and preparing method thereof
US20040247744A1 (en) * 2002-02-11 2004-12-09 Edizone, Lc Vitamin-containing orally soluble films
US20050100640A1 (en) * 2002-02-11 2005-05-12 Pearce Tony M. Microcapsule edibles
US20050003048A1 (en) * 2002-02-11 2005-01-06 Edizone, Lc Electrolyte-containing orally soluble films
US20040247649A1 (en) * 2002-02-11 2004-12-09 Edizone, Lc Medicine-containing orally soluble films
US20030224090A1 (en) * 2002-02-11 2003-12-04 Edizone, Lc Snacks of orally soluble edible films
US20040247746A1 (en) * 2002-02-11 2004-12-09 Edizone, Lc Delivery units of thick orally soluble polymer
US20030191029A1 (en) * 2002-03-28 2003-10-09 Elementis Specialties, Inc. Aqueous-based oil well drilling fluids containing high amylose starch polymers
WO2003086363A1 (en) * 2002-04-08 2003-10-23 Lavipharm Laboratories Inc. Drug-complex microparticles and methods of making/using same
US8017150B2 (en) * 2002-04-11 2011-09-13 Monosol Rx, Llc Polyethylene oxide-based films and drug delivery systems made therefrom
AU2003235294B2 (en) * 2002-05-16 2008-04-17 Kyukyu Pharmaceutical Co., Ltd. Quickly soluble film preparations
DE10224607B4 (en) * 2002-06-04 2008-03-13 Lts Lohmann Therapie-Systeme Ag Film-form, disintegratable preparations for drug release and process for their preparation
JP2004018470A (en) * 2002-06-18 2004-01-22 Takasago Internatl Corp Antimicrobial perfume composition, foul breath-preventing perfume composition, and composition for oral cavity containing the compositions
US20030235613A1 (en) * 2002-06-19 2003-12-25 Cts Chemical Industries Ltd. Popping oral administration form
US20050287231A1 (en) * 2002-06-21 2005-12-29 Nussen Kenneth H Method and apparatus for oral hygiene products with green tea extract
US20050025719A1 (en) * 2002-06-21 2005-02-03 Nussen Kenneth H. Method and apparatus for oral hygiene products with green tea extract
US20030235606A1 (en) * 2002-06-21 2003-12-25 Nussen Kenneth H. Oral hygiene products and methods of making oral hygiene products
US6937455B2 (en) * 2002-07-03 2005-08-30 Kronos Advanced Technologies, Inc. Spark management method and device
US20030235630A1 (en) * 2002-06-21 2003-12-25 Nussen Kenneth H. Dental hygiene products and methods of making dental hygiene products
US7347985B2 (en) * 2002-06-25 2008-03-25 Wm. Wrigley Jr. Company Breath freshening and oral cleansing product with magnolia bark extract
US7595065B2 (en) * 2002-06-25 2009-09-29 Wm. Wrigley Jr. Company Breath freshening and oral cleansing products with synergistic combinations of magnolia bark extract and essential oils
RU2338549C2 (en) * 2002-06-25 2008-11-20 Вм. Ригли Дж. Компани Product with extract of magnolia bark, freshening breath and disinfecting oral cavity
US7632525B2 (en) * 2002-06-25 2009-12-15 Wm. Wrigley Jr. Company Breath freshening and oral cleansing product with magnolia bark extract in combination with surface active agents
US7150780B2 (en) * 2004-01-08 2006-12-19 Kronos Advanced Technology, Inc. Electrostatic air cleaning device
US20040013723A1 (en) * 2002-07-16 2004-01-22 PARIKH Rita M. Oral care capsules
CA2505796C (en) 2002-07-22 2012-01-03 Monosolrx Llc Packaging and dispensing of rapid dissolve dosage form
US20040018156A1 (en) * 2002-07-23 2004-01-29 Szeles Lori H Enzyme enhanced breath freshening film
GB0217382D0 (en) * 2002-07-26 2002-09-04 Pfizer Ltd Process for making orally consumable dosage forms
AU2003281744B2 (en) * 2002-07-29 2005-03-10 Patrick John Shanahan Oral and dental composition
AU2002950426A0 (en) * 2002-07-29 2002-09-12 Patrick John Shanahan Anti microbial oro-dental system
US6824829B2 (en) * 2002-08-23 2004-11-30 Acupac Packaging, Inc. Process for manufacturing thin film strips
US7241411B2 (en) 2002-08-23 2007-07-10 Acupac Packaging, Inc. Thin film strips
EP1534252B1 (en) * 2002-08-27 2010-06-30 Wm. Wrigley Jr. Company Breath freshening and oral cleansing product using cardamom oil
US20040043134A1 (en) * 2002-08-27 2004-03-04 Corriveau Christine Leclair Rolled edible thin film products and methods of making same
AU2003260091A1 (en) * 2002-08-27 2004-03-19 Wm. Wrigley Jr. Company Breath freshening and oral cleansing product using carvacrol
CA2495064A1 (en) * 2002-08-27 2004-03-11 Wm. Wrigley Jr. Company Breath freshening and oral cleansing product using salicylaldehyde
AU2003265964A1 (en) * 2002-09-06 2004-03-29 Mars, Incorporated Edible films having distinct regions
US20040120991A1 (en) * 2002-09-07 2004-06-24 Mars Incorporated Edible films having distinct regions
US8524200B2 (en) 2002-09-11 2013-09-03 The Procter & Gamble Company Tooth whitening products
US20050019277A1 (en) * 2002-09-11 2005-01-27 The Procter & Gamble Company Tooth whitening products
US20040052853A1 (en) * 2002-09-16 2004-03-18 Cp Kelco, U.S., Inc. Pectin films
US6916463B2 (en) 2002-09-24 2005-07-12 The Procter & Gamble Company Oral products having an aesthetic layer
US20040156895A1 (en) * 2002-11-12 2004-08-12 Elan Pharma International Ltd. Solid dosage forms comprising pullulan
US9561182B2 (en) * 2003-08-22 2017-02-07 Cure Pharmaceutical Corporation Edible films for administration of medicaments to animals, methods for their manufacture and methods for their use for the treatment of animals
US8999372B2 (en) * 2002-11-14 2015-04-07 Cure Pharmaceutical Corporation Methods for modulating dissolution, bioavailability, bioequivalence and drug delivery profile of thin film drug delivery systems, controlled-release thin film dosage formats, and methods for their manufacture and use
US20040131662A1 (en) * 2003-11-12 2004-07-08 Davidson Robert S. Method and apparatus for minimizing heat, moisture, and shear damage to medicants and other compositions during incorporation of same with edible films
US20040191302A1 (en) * 2003-03-28 2004-09-30 Davidson Robert S. Method and apparatus for minimizing heat, moisture, and shear damage to medicants and other compositions during incorporation of same with edible films
AU2003295577A1 (en) * 2002-11-14 2004-06-15 Zengen, Inc. Edible film for relief of cough or symptoms associated with pharyngitis
US20040096569A1 (en) * 2002-11-15 2004-05-20 Barkalow David G. Edible film products and methods of making same
CA2508145A1 (en) * 2002-12-06 2004-06-24 Monosolrx Llc Thin film delivery systems for volatile decongestants
US20040115137A1 (en) * 2002-12-17 2004-06-17 Verrall Andrew P. Water-soluble film for oral administration
AU2003287838A1 (en) * 2002-12-26 2004-07-22 University Of Manitoba Dissolving film comprising a therapeutically active agent within the film or in a pouch formed by the film
US6669929B1 (en) * 2002-12-30 2003-12-30 Colgate Palmolive Company Dentifrice containing functional film flakes
SE0302947D0 (en) * 2003-01-24 2003-11-07 Magle Ab A composition material for transmucosal delivery
ATE553746T1 (en) * 2003-01-30 2012-05-15 Monosolrx Llc METHOD FOR PRODUCING A THIN FILM CONTAINING THERMOLABILITY ACTIVE INGREDIENTS
US20040228892A1 (en) * 2003-02-28 2004-11-18 Berry Craig J. Delivery system for cosmetic and skincare products
US7041311B2 (en) 2003-02-28 2006-05-09 International Flavors & Fragrances Inc. Preparation for saliva flow
AT414095B (en) * 2003-03-11 2006-09-15 Gebro Pharma Gmbh Preparation useful e.g. to treat dry mucous membrane in oral and throat area comprises medical and/or food organic substance, flavor material, mucoadhesive substance, sugar (alcohol) and carrier substance e.g. fat and/or oil
US20040180110A1 (en) * 2003-03-14 2004-09-16 Atul Mistry Chewing gum and confectionery compositions containing an endothermic agent
US20040185093A1 (en) * 2003-03-18 2004-09-23 Szymczak Christopher E. Compositions containing sucralose
WO2004087089A2 (en) * 2003-03-26 2004-10-14 The Procter & Gamble Company Rapidly dissolving edible film compositions with improved film strength and stability
EP1605905A1 (en) * 2003-03-26 2005-12-21 The Procter & Gamble Company Rapidly dissolving edible film compositions with cellulose film forming polymers
US20040202698A1 (en) * 2003-04-02 2004-10-14 The Procter & Gamble Company Drug delivery systems comprising an encapsulated active ingredient
US20040202755A1 (en) * 2003-04-08 2004-10-14 Myers Gale D. Speckled confection pieces
EP1620059A2 (en) * 2003-04-14 2006-02-01 Fmc Corporation Delivery systems of homogeneous, thermoreversible gel film containing kappa-2 carrageenan
US6708826B1 (en) 2003-04-30 2004-03-23 Warner-Lambert Company, Llc Packaged supply of individual doses of a personal care product
GB0312425D0 (en) * 2003-05-30 2003-07-09 Boots Co Plc Use of a compound in the treatment of sleep disorders and the like,in providing refreshedness on waking and a method for the treatment of grogginess therewith
GB0312419D0 (en) * 2003-05-30 2003-07-02 Boots Healthcare Int Ltd Use of a compound in the treatment of sleep disorders and the like, in providing refreshedness on waking and a method for the treatment of grogginess
DE10325140B4 (en) * 2003-06-04 2014-12-31 Lts Lohmann Therapie-Systeme Ag Direct coating method and apparatus
US8703209B2 (en) * 2003-06-17 2014-04-22 Edward Larry McCleary Composition and method for modulating hydrogen ion physiology
WO2005004989A2 (en) * 2003-07-01 2005-01-20 Todd Maibach Film comprising therapeutic agents
ES2654062T3 (en) * 2003-07-24 2018-02-12 Glaxosmithkline Llc Oral Dissolution Films
US20050069501A1 (en) * 2003-08-15 2005-03-31 Sayed Ibrahim Rapid temporary tooth whitening composition
US7666396B2 (en) * 2003-09-11 2010-02-23 Kimberly-Clark Worldwide, Inc. Single-use moisturizing product
US20050072443A1 (en) * 2003-10-06 2005-04-07 Kuchenbecker Lee Ann Dental hygiene accessories
US20050075432A1 (en) * 2003-10-07 2005-04-07 Verrall Andrew P. Acidulent film and method of making same
US20050079253A1 (en) * 2003-10-10 2005-04-14 Hiroshi Nakamura Bilayer edible sheet
US9248146B2 (en) * 2003-10-24 2016-02-02 Adhesives Research, Inc. Dissolvable adhesive films for delivery of pharmaceutical or cosmetic agents
CA2543324C (en) 2003-10-24 2011-02-01 Adhesives Research, Inc. Rapidly disintegrating films for delivery of pharmaceutical or cosmetic agents
NO320283B1 (en) * 2003-10-30 2005-11-21 Ntnu Technology Transfer As Use of the plant Sphagnum, oral hygiene product and methods for controlling unwanted bacterial flora on teeth
CA2544078C (en) * 2003-11-03 2013-08-06 Hill's Pet Nutrition, Inc. Coated pet food composition
US8627828B2 (en) 2003-11-07 2014-01-14 U.S. Smokeless Tobacco Company Llc Tobacco compositions
AU2004289248B2 (en) 2003-11-07 2012-05-03 U.S. Smokeless Tobacco Company Llc Tobacco compositions
US7182964B2 (en) * 2003-11-13 2007-02-27 Dbc, Llc Dissolving thin film xanthone supplement
DE10354894A1 (en) * 2003-11-24 2005-07-07 Hf Arzneimittelforschung Gmbh Oral formulations of deoxypeganine and their applications
US7285520B2 (en) 2003-12-01 2007-10-23 Kimberly-Clark Worldwide, Inc. Water disintegratable cleansing wipes
RU2006125452A (en) 2003-12-16 2008-01-27 Колгейт-Палмолив Компани (US) COMPOSITIONS AND METHODS FOR CARE OF THE ORAL CAVITY AND BODY
US20050136112A1 (en) * 2003-12-19 2005-06-23 Pediamed Pharmaceuticals, Inc. Oral medicament delivery system
MXPA06007043A (en) 2003-12-19 2007-05-23 Univ Melbourne Antimicrobial composition.
US20050137262A1 (en) * 2003-12-22 2005-06-23 Hu Patrick C. Highly concentrated pourable aqueous solutions of potassium ibuprofen, their preparation and their uses
DE102004002951A1 (en) * 2004-01-21 2005-08-11 Wella Ag Process for producing hair-setting products in film form
WO2005074894A1 (en) 2004-01-30 2005-08-18 Corium International Rapidly dissolving film for delivery of an active agent
AR047658A1 (en) 2004-02-03 2006-02-01 Cargill Inc CONCENTRATE OF PROTEINS AND WATER CURRENT WITH HYDROSOLUBBLE CARBOHYDRATES
US20050186256A1 (en) * 2004-02-20 2005-08-25 Dihel Deborah L. Dissolvable film comprising an active ingredient and method of manufacture
US20050186257A1 (en) * 2004-02-20 2005-08-25 Todd Manegold Dissolvable film and method of manufacture
US20050196355A1 (en) * 2004-03-03 2005-09-08 Constantine Georgiades Film products having controlled disintegration properties
US20070190125A1 (en) 2004-03-03 2007-08-16 Constantine Georgiades Positioning feature for aiding use of film or strip product
US20080003248A1 (en) * 2004-03-03 2008-01-03 Constantine Georgiades Whitening products
US20050196497A1 (en) * 2004-03-03 2005-09-08 Kraft Foods Holdings, Inc. Antimicrobial effect of chitosan in beverages
US20050196348A1 (en) * 2004-03-03 2005-09-08 Constantine Georgiades Stabilized peroxide compositions
US20050196354A1 (en) * 2004-03-03 2005-09-08 Andre Soshinsky Film compositions
EP1732507A1 (en) * 2004-03-03 2006-12-20 Warner-Lambert Company LLC Stabilized peroxide compositions
US20070269519A1 (en) * 2004-03-03 2007-11-22 Constantine Georgiades Whitening products
US20050208108A1 (en) * 2004-03-19 2005-09-22 Jannusch Leonard C Thermoplastic films and methods for making
US20050226964A1 (en) * 2004-04-07 2005-10-13 Michael Small Water soluble seal and cap
US7850987B2 (en) * 2004-04-08 2010-12-14 Micronutrient, Llc Nutrient composition(s) and system(s) for individualized, responsive dosing regimens
US20050226906A1 (en) * 2004-04-08 2005-10-13 Micro Nutrient, Llc Nutrient system for individualized responsive dosing regimens
US7785619B2 (en) * 2004-04-08 2010-08-31 Micro Nutrient, Llc Pharmanutrient composition(s) and system(s) for individualized, responsive dosing regimens
US20050230871A1 (en) * 2004-04-20 2005-10-20 Bess William S Fast-dissolving films
EP1593376A1 (en) * 2004-05-04 2005-11-09 Warner-Lambert Company LLC Improved pullulan capsules
US7118732B2 (en) * 2004-05-10 2006-10-10 Colgate-Palmolive Company Tooth-whitening compositions comprising silicone polymer and methods therefor
CA2470463C (en) 2004-06-09 2012-09-18 Lornamead Brands, Inc. Tooth whitening products and methods of making the same
WO2005120455A1 (en) * 2004-06-12 2005-12-22 Passion For Life Healthcare Limited Soluble strip for oral or topical administration
US7281541B2 (en) * 2004-06-16 2007-10-16 Lorch Leonard G Dental floss
US20050281757A1 (en) * 2004-06-17 2005-12-22 Sayed Ibrahim Oral care film
US9267167B2 (en) * 2004-06-28 2016-02-23 Becton, Dickinson And Company Dissolvable films and methods including the same
US7334538B1 (en) * 2004-07-27 2008-02-26 Aquascience Research Group, Inc. Topical medicants for aquatic animals
US20060024425A1 (en) 2004-07-30 2006-02-02 Wm. Wrigley Jr. Company Edible film compositions
BRPI0514037B8 (en) * 2004-08-02 2021-05-25 Glaxo Group Ltd composition for oral care
MX2007001512A (en) 2004-08-05 2007-04-20 Corium Int Inc Adhesive composition.
US7959902B1 (en) * 2004-09-21 2011-06-14 Postlewaite Laura M Device and method for treating the oral cavity
US20060062811A1 (en) * 2004-09-21 2006-03-23 Szymczak Christopher E Medicinal cooling emulsions
DK1791791T3 (en) * 2004-09-27 2019-08-26 Special Water Patents B V Methods and compositions for treating water
WO2007099398A2 (en) 2005-09-27 2007-09-07 Naturalite Benelux B.V. Methods and compositions for treatment of skin
KR101388955B1 (en) * 2004-09-30 2014-04-24 더 허쉬 컴퍼니 Sealed, edible film strip packets and methods of making and using them
CA2582326A1 (en) * 2004-09-30 2006-04-13 Homaro R. Cantu System and methods for preparing substitute food items
US20060104910A1 (en) * 2004-11-15 2006-05-18 Keith Lerner Over dosage indicating medicated film strip
US8758816B2 (en) * 2004-11-24 2014-06-24 Meda Pharmaceuticals Inc. Compositions comprising azelastine and methods of use thereof
HUE031470T2 (en) 2004-11-24 2017-07-28 Meda Pharmaceuticals Inc Compositions comprising azelastine and methods of use thereof
US20070020330A1 (en) 2004-11-24 2007-01-25 Medpointe Healthcare Inc. Compositions comprising azelastine and methods of use thereof
KR100701409B1 (en) * 2004-11-26 2007-03-30 한국유나이티드제약 주식회사 Pharmaceutical formulations containing sumatriptan succinate
CA2596311A1 (en) * 2005-01-20 2006-07-27 Stephen Holt Herbal compositions containing hoodia
NZ556713A (en) 2005-02-02 2010-01-29 Novapharm Res Australia Biostatic polymer
US20070275135A1 (en) * 2005-02-09 2007-11-29 First Flavor, Inc. Taste sampling process and product
RU2401232C2 (en) 2005-02-14 2010-10-10 МакНЕЙЛ-ППС, ИНК. Package for individual medicinal agents
CA2603139A1 (en) * 2005-03-04 2006-09-08 Technologies Pharmaguild Inc. Amine-based and imine-based polymers, uses and preparation thereof
US20060207721A1 (en) * 2005-03-17 2006-09-21 Greg Slominski Polymer adhesive splicing of water-soluble, orally ingestible thin film webs
WO2006107390A2 (en) 2005-04-04 2006-10-12 Kronos Advanced Technologies, Inc. An electrostatic fluid accelerator for and method of controlling a fluid flow
US8597709B2 (en) 2005-04-12 2013-12-03 Inovobiologic Inc. Dietary supplement and methods of use
US8062686B2 (en) 2005-04-12 2011-11-22 InovoBiologics, Inc. Dietary supplement, and methods of use
KR20080007449A (en) * 2005-05-03 2008-01-21 이노젠, 인크. Edible film for transmucosal delivery of nutritional supplements
US20060254949A1 (en) * 2005-05-12 2006-11-16 Staggs William B Jr Credit card-shaped drug delivery system
US9023382B2 (en) * 2005-06-08 2015-05-05 Basf Corporation Medicament carrier composition and method of forming a film therefrom
WO2007011958A2 (en) 2005-07-15 2007-01-25 Emisphere Technologies, Inc. Intraoral dosage forms of glucagon
WO2007022229A1 (en) * 2005-08-18 2007-02-22 Colgate-Palmolive Company Cleansing compositions containing film
US7861728B2 (en) * 2006-02-10 2011-01-04 R.J. Reynolds Tobacco Company Smokeless tobacco composition having an outer and inner pouch
US20070077300A1 (en) * 2005-09-30 2007-04-05 Wynn David W Oral compositions containing a salivation inducing agent
US20070098746A1 (en) * 2005-11-02 2007-05-03 Nichols William M Multi-layered coating technology for taste masking
CN101321513A (en) * 2005-12-02 2008-12-10 Gic创新公司 Vehicles for oral care with magnolia bark extract
DK1954301T3 (en) * 2005-12-02 2013-08-05 Gic Innovations Company CONFECTURE COMPOSITIONS WITH MAGNOLIA BARK EXTRACT
US7544377B2 (en) * 2005-12-02 2009-06-09 Gic Innovations Company Chewable compositions with fast release magnolia bark extract
US20070134297A1 (en) * 2005-12-08 2007-06-14 Naqam Washington Device to aid in sexual pleasure
US20070137668A1 (en) * 2005-12-15 2007-06-21 Borschke August J Smoking articles and wrapping materials therefor
US20070140992A1 (en) * 2005-12-21 2007-06-21 Lynn Schick Taste masking of essential oils using a hydrocolloid
US20070148213A1 (en) * 2005-12-22 2007-06-28 Sayed Ibrahim Film containing compositions
WO2007078874A2 (en) * 2005-12-30 2007-07-12 Cogentus Pharmaceuticals, Inc. Oral pharmaceutical formulations containing non-steroidal anti-inflammatory drugs and acid inhibitors
WO2007084587A2 (en) * 2006-01-20 2007-07-26 Monosol Rx, Llc Film lined pouch and method of manufacturing this pouch
US7810507B2 (en) * 2006-02-10 2010-10-12 R. J. Reynolds Tobacco Company Smokeless tobacco composition
AU2007214474B2 (en) * 2006-02-17 2011-01-20 Novartis Ag Disintegrable oral films
WO2007100653A2 (en) * 2006-02-23 2007-09-07 E. I. Du Pont De Nemours And Company Removable antimicrobial coating compositions and methods of use
US8986735B2 (en) * 2006-03-16 2015-03-24 Novartis Ag Solid dosage form containing a taste masked active agent
US20070218090A1 (en) * 2006-03-17 2007-09-20 Craig Berry Dissolvable strip for delivery of an agent
US20070231387A1 (en) * 2006-04-04 2007-10-04 Luigi Levi Film-coated solid dosage forms
SI2007362T1 (en) 2006-04-04 2018-12-31 Kg Acquisition Llc Oral dosage forms including an antiplatelet agent and an acid inhibitor
US20070235350A1 (en) * 2006-04-06 2007-10-11 John Warlick Wallet Sized Medicament Dispenser
US20070235349A1 (en) * 2006-04-06 2007-10-11 General Patent, Llc Medicament Dispenser
WO2007127810A2 (en) * 2006-04-25 2007-11-08 Kronos Advanced Technologies, Inc. Electrostatic loudspeaker and method of acoustic waves generation
IL175338A0 (en) * 2006-05-01 2006-09-05 Biota Ltd Orally administrable films and preparation thereof
US8187659B2 (en) * 2006-05-02 2012-05-29 Jerry Robertson Real Estate Llc Solid medicament dosage form consumption aid
US7946296B2 (en) 2006-05-26 2011-05-24 Philip Morris Usa Inc. Dissolvable tobacco film strips and method of making the same
WO2007143676A2 (en) * 2006-06-05 2007-12-13 Verus Pharmaceuticals, Inc. Epinephrine dosing regimens comprising buccal, lingual or sublingual and injectable dosage forms
WO2007143674A2 (en) * 2006-06-05 2007-12-13 Verus Pharmaceuticals, Inc. Methods for buccal, lingual or sublingual dosing regimens of epinephrine for the treatment of allergic emergencies
JP4859115B2 (en) * 2006-06-07 2012-01-25 松谷化学工業株式会社 Edible film for oral hygiene
US20070292481A1 (en) * 2006-06-16 2007-12-20 Hoffman Andrew J Packaging of Food Products with Pullulan Films
US20080152761A1 (en) * 2006-12-20 2008-06-26 Shiji Shen Packaging of Food Products with Pullulan Films
US20070298078A1 (en) * 2006-06-27 2007-12-27 Harrison Michael D Water Soluble Article for Imparting Dietary Fiber to Bottled Water
CN101489519B (en) * 2006-07-14 2013-05-08 宝洁公司 Treatment articles capable of delivering intensive care and overall treatment simultaneously
US20080014228A1 (en) * 2006-07-14 2008-01-17 Olivia Darmuzey Solid form
US20080026062A1 (en) * 2006-07-31 2008-01-31 Isaac Farr Pharmaceutical compositions including nano-sized active agent
US20080026040A1 (en) * 2006-07-31 2008-01-31 Isaac Farr Active agent-releasing dosage forms
WO2008028278A1 (en) * 2006-09-05 2008-03-13 University Of Manitoba Antimicrobial coatings
JP5014712B2 (en) * 2006-09-06 2012-08-29 ライオン株式会社 Oral dissolution film
AU2007297697A1 (en) * 2006-09-20 2008-03-27 Monosol Rx Llc Edible water-soluble film containing a foam reducing flavoring agent
CA2664615A1 (en) * 2006-09-29 2008-04-10 Monosol Rx, Llc Film embedded packaging and method of making same
KR101448050B1 (en) * 2006-10-02 2014-10-14 랍테크 게젤샤프트 퓌르 테히놀로기슈 포르슝 운트 엔트빅클룽 엠베하 Non-mucoadhesive film dosage forms
US20100172956A1 (en) * 2006-10-13 2010-07-08 Thomas Kalili Dissolving strip for oral mucosa as a systemic drug delivery route
DE102006061287A1 (en) * 2006-12-22 2008-06-26 Lts Lohmann Therapie-Systeme Ag Edible foil-shaped preparation with cola flavor
US20090198262A1 (en) * 2006-12-26 2009-08-06 Discus Dental, Llc Disposable tongue scraper
US20100215774A1 (en) * 2007-02-09 2010-08-26 Todd Maibach Film comprising nitroglycerin
WO2008109018A1 (en) * 2007-03-02 2008-09-12 Meda Pharmaceuticals Inc. Compositions comprising carisoprodol and methods of use thereof
US20080220029A1 (en) * 2007-03-05 2008-09-11 Charlene Ng Fast-dissolving/disintegrating film preparation having high proportion of active
CN101621990B (en) * 2007-03-07 2012-11-21 诺瓦提斯公司 Orally administrable films
US20090011115A1 (en) * 2007-03-13 2009-01-08 Foss Carter D Edible Pullulan Films Containing Flavoring
US8568777B2 (en) * 2007-03-30 2013-10-29 Monosol Rx, Llc Packaged film dosage unit containing a complexate
US8900629B2 (en) 2007-04-05 2014-12-02 University Of Kansas Rapidly dissolving pharmaceutical compositions comprising pullulan
WO2008124617A2 (en) 2007-04-05 2008-10-16 University Of Kansas Rapidly dissolving pharmaceutical compositions comprising pullulan
US20080274252A1 (en) * 2007-04-12 2008-11-06 Hoffman Andrew J Pullulan film containing sweetener
US20080260836A1 (en) * 2007-04-18 2008-10-23 Thomas James Boyd Films Comprising a Plurality of Polymers
US20080274187A1 (en) * 2007-05-02 2008-11-06 J.C. Bright M. Ltd. Hard capsule composition and method of use
US20080279903A1 (en) * 2007-05-07 2008-11-13 Liu Hwa-Song Edible thin film strips and process for making
US20080311162A1 (en) * 2007-05-16 2008-12-18 Olivia Darmuzey Solid form
JP5177447B2 (en) * 2007-06-07 2013-04-03 佐藤製薬株式会社 Film preparation having fast solubility and flexibility
CN101073407B (en) * 2007-06-15 2011-04-20 广东富味制果厂有限公司 Edible refreshing pearl and its production
US20090004254A1 (en) * 2007-06-19 2009-01-01 Todd Maibach Film comprising active drugs
WO2008157033A1 (en) 2007-06-20 2008-12-24 Mcneil-Ppc, Inc Products for whitening teeth
JP5101191B2 (en) * 2007-06-29 2012-12-19 リンテック株式会社 Film-form preparation and method for producing the same
US20090010998A1 (en) * 2007-07-03 2009-01-08 Marchitto Kevin S Drug-delivery patch comprising a dissolvable layer and uses thereof
CN101873809B (en) 2007-07-23 2014-11-12 R.J.雷诺兹烟草公司 Smokeless tobacco compositions
US8968709B2 (en) 2007-07-25 2015-03-03 3M Innovative Properties Company Therapeutic dental composition and related methods
CA2695157A1 (en) * 2007-07-31 2009-02-05 Bill Mcanalley And Associates, Llc Compositions, uses, and method of making wound care products from naturally occurring food ingredients
KR100937625B1 (en) * 2007-08-10 2010-01-20 주식회사 제닉 Dissolvable Web Porous Film and Preparing Method Thereof
US8323695B2 (en) 2007-08-13 2012-12-04 Mcneil-Ppc, Inc. Method for stabilizing phenylephrine
JP2009096803A (en) * 2007-09-26 2009-05-07 Showa Kako Kk Oral cavity patch type slowly soluble preparation
WO2009043588A2 (en) * 2007-10-02 2009-04-09 LABTEC Gesellschaft für technologische Forschung und Entwicklung mbH Ph regulating antibacterial films for the oral or vaginal cavity
KR100905027B1 (en) * 2007-10-03 2009-06-30 (주)씨엘팜 Edible Film
MY185299A (en) 2007-10-11 2021-04-30 Philip Morris Products Sa Smokeless tobacco product
US9125434B2 (en) 2007-10-11 2015-09-08 Philip Morris Products S.A. Smokeless tobacco product, smokeless tobacco product in the form of a sheet, extrudable tobacco composition, method for manufacturing a smokeless tobacco product, method for delivering super bioavailable nicotine contained in tobacco to a user, and packaged smokeless tobacco product sheet
US20090098192A1 (en) * 2007-10-11 2009-04-16 Fuisz Richard C Extrudable and Extruded Compositions for Delivery of Bioactive Agents, Method of Making Same and Method of Using Same
US20090142452A1 (en) * 2007-11-19 2009-06-04 Michael David Campbell Dissolvable Orally Consumable Flavored Sensual Enhancement Films
US20090253754A1 (en) * 2007-12-04 2009-10-08 Francesca Selmin Fast dissolving films and coatings for controlled release of flavors, active pharmaceutical ingredients, food substances, and nicotine
EP2489656A1 (en) 2007-12-21 2012-08-22 Ligand Pharmaceuticals Inc. Selective androgen receptor modulators (sarms) and uses thereof
US20090162516A1 (en) * 2007-12-21 2009-06-25 Brown Solomon E Edible, water-soluble film
CA2930063C (en) 2008-01-04 2017-01-31 Schabar Research Associates Llc Unit oral solid dose compositions composed of naproxen sodium and nizatidine
WO2009099830A2 (en) * 2008-01-31 2009-08-13 Mcneil-Ppc, Inc. Edible film-strips for immediate release of active ingredients
EP2234606A2 (en) * 2008-01-31 2010-10-06 McNeil-PPC, Inc. Edible film-strips with modified release active ingredients
US8497409B2 (en) 2008-02-29 2013-07-30 Kimberly-Clark Worldwide, Inc. Absorbent article having an olfactory wetness signal
ES2525123T3 (en) 2008-06-04 2014-12-17 Colgate-Palmolive Company Implementation for oral care with cavitation system
GB2462022B (en) 2008-06-16 2011-05-25 Biovascular Inc Controlled release compositions of agents that reduce circulating levels of platelets and methods thereof
EP2324833B1 (en) * 2008-08-25 2017-07-19 Kyukyu Pharmaceutical Co., Ltd. Film preparation containing loperamide hydrochloride
US8715715B2 (en) 2008-11-03 2014-05-06 Nal Pharmaceuticals Ltd. Dosage form for insertion into the mouth
AU2010204863A1 (en) * 2009-01-13 2011-09-01 Monosol Rx Llc Unit assembly for multiple film dosages, apparatus, and methods
EP2387394B1 (en) 2009-01-14 2018-05-02 Corium International, Inc. Transdermal administration of tamsulosin
US20100183717A1 (en) 2009-01-16 2010-07-22 Kristin Arnold Controlled-release formulations
US20100209484A1 (en) * 2009-02-13 2010-08-19 Hoo-Kyun Choi Transdermal Triptan Delivery System
MX357919B (en) * 2009-03-13 2018-07-25 Nucitec Sa De Cv Compositions and methods for treatment and prevention of cardiovascular disease.
EP2233134A1 (en) 2009-03-27 2010-09-29 McNeil AB Multi-portion intra-oral dosage form with organoleptic properties
US20100256215A1 (en) * 2009-04-02 2010-10-07 Silver Eagle Labs Nv, Llc Menthol-Melatonin Dissolving Film
US20100256197A1 (en) * 2009-04-02 2010-10-07 Silver Eagle Labs Nv, Llc Nicotine Dissolving Film With Or Without Menthol
JP2010254603A (en) * 2009-04-23 2010-11-11 Osaka Univ Oral cavity composition
MX339923B (en) 2009-05-26 2016-06-16 Colgate-Palmolive Company * Dentifrice composition.
TWI396554B (en) 2009-05-26 2013-05-21 Colgate Palmolive Co Oral care formulations that enhance amount of soluble zinc
TWI442937B (en) * 2009-05-26 2014-07-01 Colgate Palmolive Co Higher loading zinc-containing films
WO2010150930A1 (en) * 2009-06-25 2010-12-29 (주)벡스코아 Fast dissolving film for oral administration which prevents unpleasant taste effectively
US20110177146A1 (en) * 2009-07-27 2011-07-21 E. I. Du Pont De Nemours And Company Removable antimicrobial coating compositions containing cationic rheology agent and methods of use
WO2011014401A2 (en) * 2009-07-30 2011-02-03 The Procter & Gamble Company Oral care articles and methods
US20110027199A1 (en) * 2009-07-30 2011-02-03 Danny Frye Drink container with a breath strip
US8475832B2 (en) 2009-08-07 2013-07-02 Rb Pharmaceuticals Limited Sublingual and buccal film compositions
TR200907338A1 (en) * 2009-09-28 2011-04-21 Yedi̇tepe Üni̇versi̇tesi̇ A film strip containing natural ingredients.
SI3403654T1 (en) 2009-10-01 2019-10-30 Adare Dev I L P Orally administered corticosteroid compositions
US8357398B2 (en) * 2009-10-21 2013-01-22 Alitair Pharmaceuticals Inc. Benzonatate compositions and methods of use
WO2014057351A1 (en) * 2012-10-11 2014-04-17 Ix Biopharma Ltd Solid dosage form
US9549842B2 (en) 2011-02-04 2017-01-24 Joseph E. Kovarik Buccal bioadhesive strip and method of treating snoring and sleep apnea
US8701671B2 (en) 2011-02-04 2014-04-22 Joseph E. Kovarik Non-surgical method and system for reducing snoring
US9408798B2 (en) 2009-12-04 2016-08-09 Colgate-Palmolive Company Dissolvable films containing high concentrations of nonionic surfactants such as polysorbates to enhance high solid loadings
US20110136815A1 (en) * 2009-12-08 2011-06-09 Horst Zerbe Solid oral film dosage forms and methods for making same
US10610528B2 (en) 2009-12-08 2020-04-07 Intelgenx Corp. Solid oral film dosage forms and methods for making same
PT2519225E (en) 2009-12-30 2015-07-27 Novartis Ag Melt extruded nicotine thin strips
EP2519224A1 (en) 2009-12-30 2012-11-07 Novartis AG Melt extruded thin strips containing coated pharmaceutical actives
TWI458497B (en) 2010-01-13 2014-11-01 Colgate Palmolive Co Stabilization of zinc oxide film in oral compositions
TWI435733B (en) * 2010-01-29 2014-05-01 Colgate Palmolive Co Oral care formulations for malodor control
US8397945B2 (en) 2010-02-23 2013-03-19 R.J. Reynolds Tobacco Company Dispensing container
WO2011108643A1 (en) * 2010-03-03 2011-09-09 救急薬品工業株式会社 Film preparation containing medicament with unpleasant taste
DE102010014869A1 (en) * 2010-04-13 2011-10-13 Lts Lohmann Therapie-Systeme Ag Hydrogel for natural cosmetic purposes
US20110268809A1 (en) 2010-04-28 2011-11-03 Paul Andrew Brinkley Nicotine-Containing Pharmaceutical Compositions
US20110274628A1 (en) 2010-05-07 2011-11-10 Borschke August J Nicotine-containing pharmaceutical compositions
US8232238B2 (en) 2010-06-03 2012-07-31 The Clorox Company Concentrated film delivery systems
WO2011156711A1 (en) 2010-06-10 2011-12-15 Schobel Alexander M Nanoparticle film delivery systems
JP2013529633A (en) 2010-06-23 2013-07-22 コルゲート・パーモリブ・カンパニー Encapsulation of ingredients in a lactose matrix to form an effective encapsulating agent
EP2588200B1 (en) 2010-06-30 2018-02-28 Colgate-Palmolive Company Multilayer films for delivery of flavor
US20130095159A1 (en) 2010-06-30 2013-04-18 Colgate-Palmolive Company Flavor release from multilayer film during brushing
EP2588288B1 (en) 2010-07-02 2015-10-28 The Procter and Gamble Company Process for making films from nonwoven webs
EP2588653B1 (en) 2010-07-02 2018-06-20 The Procter and Gamble Company Method of treating a fabric article
ES2792800T3 (en) 2010-07-02 2020-11-12 Procter & Gamble Methods of delivery of a health care active substance by administering personal health care items comprising a filament
RU2640933C1 (en) 2010-07-02 2018-01-12 Дзе Проктер Энд Гэмбл Компани Filaments containing active components, suitable for oral supplementation, non-woven fabrics and methods of manufacturing them
MX2012015187A (en) 2010-07-02 2013-05-09 Procter & Gamble Method for delivering an active agent.
MX345025B (en) 2010-07-02 2017-01-12 Procter & Gamble Detergent product.
US10028520B2 (en) 2010-09-02 2018-07-24 R.J. Reynolds Tobacco Company Apparatus for manufacturing a smokeless tobacco product incorporating an object, and associated method
DE102010048408A1 (en) 2010-10-15 2012-04-19 Lts Lohmann Therapie-Systeme Ag Laminate with improved water retention behavior
US9149959B2 (en) 2010-10-22 2015-10-06 Monosol Rx, Llc Manufacturing of small film strips
US10238684B2 (en) 2010-11-18 2019-03-26 Foundational Biosystems, Llc Micro- and nano-quantity sleep enhancing nutrient composition and method of enhancing central nervous system protein clearance using same
MY163370A (en) 2010-12-07 2017-09-15 Colgate Palmolive Co Oral and personal care compositions
US9648874B2 (en) * 2010-12-07 2017-05-16 Kimberly-Clark Worldwide, Inc. Natural, multiple use and re-use, user saturated wipes
RU2582945C2 (en) 2010-12-23 2016-04-27 Колгейт-Палмолив Компани Liquid compositions, containing structuring agent
CN103260600B (en) 2010-12-23 2015-12-02 高露洁-棕榄公司 Comprise the aqueous oral care composition of xanthan gum, cellulose gum and carbomer
EP2663294B1 (en) 2011-01-11 2015-09-30 Capsugel Belgium NV New hard capsules comprising pullulan
US9277976B2 (en) 2011-01-24 2016-03-08 Leonard G. Lorch Dental floss
US9277977B2 (en) 2011-01-24 2016-03-08 Leonard G. Lorch Dental floss
US8381742B2 (en) 2011-01-24 2013-02-26 Leonard G. Lorch Dental floss
US10206765B2 (en) 2011-01-24 2019-02-19 Leonard G. Lorch Dental floss
US11357722B2 (en) 2011-02-04 2022-06-14 Seed Health, Inc. Method and system for preventing sore throat in humans
US11951139B2 (en) 2015-11-30 2024-04-09 Seed Health, Inc. Method and system for reducing the likelihood of osteoporosis
US11844720B2 (en) 2011-02-04 2023-12-19 Seed Health, Inc. Method and system to reduce the likelihood of dental caries and halitosis
US10085938B2 (en) 2011-02-04 2018-10-02 Joseph E. Kovarik Method and system for preventing sore throat in humans
US11951140B2 (en) 2011-02-04 2024-04-09 Seed Health, Inc. Modulation of an individual's gut microbiome to address osteoporosis and bone disease
EP2701534A1 (en) 2011-04-28 2014-03-05 ACME Specialty Products, LLC Taste masking compositions and edible forms thereof
KR101303479B1 (en) * 2011-07-28 2013-09-06 (주)씨엘팜 Composition for edible film and pharmaceutical preparation for edible film containing drugs
JP5496287B2 (en) * 2011-09-15 2014-05-21 ローム アンド ハース カンパニー Low gloss aqueous coating composition containing poly (ethylene oxide) for use in leather
JP5781037B2 (en) * 2011-09-15 2015-09-16 ローム アンド ハース カンパニーRohm And Haas Company Low gloss aqueous coating composition comprising poly (ethylene oxide)
US9084439B2 (en) 2011-09-22 2015-07-21 R.J. Reynolds Tobacco Company Translucent smokeless tobacco product
US20130078307A1 (en) 2011-09-22 2013-03-28 Niconovum Usa, Inc. Nicotine-containing pharmaceutical composition
US9629392B2 (en) 2011-09-22 2017-04-25 R.J. Reynolds Tobacco Company Translucent smokeless tobacco product
US9474303B2 (en) 2011-09-22 2016-10-25 R.J. Reynolds Tobacco Company Translucent smokeless tobacco product
WO2013049507A1 (en) 2011-09-30 2013-04-04 Perio Sciences, Llc Antioxidant compositions for treatment of inflammation or oxidative damage
US9907748B2 (en) 2011-10-21 2018-03-06 Niconovum Usa, Inc. Excipients for nicotine-containing therapeutic compositions
CN107648070A (en) 2011-12-15 2018-02-02 高露洁-棕榄公司 Aqueous oral care composition
US8574628B2 (en) * 2011-12-19 2013-11-05 Kimberly-Clark Worldwide, Inc. Natural, multiple release and re-use compositions
US9763928B2 (en) 2012-02-10 2017-09-19 Niconovum Usa, Inc. Multi-layer nicotine-containing pharmaceutical composition
US9420825B2 (en) 2012-02-13 2016-08-23 R.J. Reynolds Tobacco Company Whitened tobacco composition
JP6050031B2 (en) * 2012-06-01 2016-12-21 森下仁丹株式会社 Film formulation
PL2866592T3 (en) * 2012-06-28 2017-01-31 Optimags Dr Zimmermann Gmbh Method for producing a film formulation for an edible film, and the use thereof
CA2878680C (en) 2012-07-23 2019-09-17 Crayola, Llc Dissolvable films and methods of using the same
CN102836144A (en) * 2012-09-28 2012-12-26 天津市聚星康华医药科技有限公司 Deoxidized epinephrine oral instant film and preparation method thereof
DE202013000446U1 (en) * 2012-10-04 2013-10-07 Maria Clementine Martin Klosterfrau Vertriebsgesellschaft Mbh Composition, in particular pharmaceutical composition, in particular for administration in hoarseness and sore throat
CN102871984B (en) * 2012-11-05 2015-11-11 天津市聚星康华医药科技有限公司 A kind of Phenylephrine hydrochloride oral instant membrane and preparation method thereof
US8859005B2 (en) 2012-12-03 2014-10-14 Intercontinental Great Brands Llc Enteric delivery of functional ingredients suitable for hot comestible applications
WO2014105783A1 (en) * 2012-12-28 2014-07-03 Noven Pharmaceuticals, Inc. Compositions and methods for transdermal delivery of amphetamine and clonidine
US9545376B2 (en) 2013-01-23 2017-01-17 Arx, Llc Production of unit dose constructs
WO2014120566A1 (en) * 2013-01-31 2014-08-07 The Procter & Gamble Company Cleansing composition and a wet wipe comprising the same
US20140255452A1 (en) 2013-03-11 2014-09-11 Niconovum Usa, Inc. Method and apparatus for differentiating oral pouch products
EP2968196A2 (en) 2013-03-14 2016-01-20 Altria Client Services LLC Soft oral product
WO2014145699A1 (en) 2013-03-15 2014-09-18 New Jersey Institute Of Technology System and method for fabrication of uniform polymer films containing nano and micro particles via continuous drying process
US9278050B2 (en) 2013-04-01 2016-03-08 Trevor Anderson Dissolvable medication administration bag and method of using the same
PH12014000076A1 (en) 2013-07-01 2015-09-07 Priscila F Kimes Improved processes in the preparation of coconut meat based composition and films
TW201503831A (en) * 2013-07-11 2015-02-01 Agrofresh Inc Humidity activated formulation for volatile compounds
TW201536214A (en) * 2013-07-16 2015-10-01 Colgate Palmolive Co System and method for making an oral care formulation
WO2015034678A2 (en) 2013-09-06 2015-03-12 Aptalis Pharmatech, Inc. Corticosteroid containing orally disintegrating tablet compositions for eosinophilic esophagitis
US11503853B2 (en) 2013-09-09 2022-11-22 R.J. Reynolds Tobacco Company Smokeless tobacco composition incorporating a botanical material
US10357054B2 (en) 2013-10-16 2019-07-23 R.J. Reynolds Tobacco Company Smokeless tobacco pastille
WO2015068058A1 (en) 2013-11-06 2015-05-14 Rk Technology & Investments Pte. Ltd. Tobacco free 'niconuts'and the process thereof
WO2015066819A1 (en) 2013-11-08 2015-05-14 Carlos Filipe Method of stabilizing molecules without refrigeration using water soluble polymers and applications thereof in performing chemical reactions
US9668970B2 (en) 2013-12-02 2017-06-06 Intelgenx Corp. Film dosage form with extended release mucoadhesive particles
US10272038B2 (en) 2013-12-02 2019-04-30 Intelgenx Corp. Film dosage form with extended release mucoadhesive particles
US11033493B2 (en) 2013-12-02 2021-06-15 Intelgenx Corp. Film dosage form with extended release mucoadhesive particles
US11833177B2 (en) 2013-12-20 2023-12-05 Seed Health, Inc. Probiotic to enhance an individual's skin microbiome
US11839632B2 (en) 2013-12-20 2023-12-12 Seed Health, Inc. Topical application of CRISPR-modified bacteria to treat acne vulgaris
US11826388B2 (en) 2013-12-20 2023-11-28 Seed Health, Inc. Topical application of Lactobacillus crispatus to ameliorate barrier damage and inflammation
US10441567B2 (en) 2014-01-17 2019-10-15 Ligand Pharmaceuticals Incorporated Methods and compositions for modulating hormone levels
US9392814B2 (en) 2014-06-06 2016-07-19 Nicholas J. Singer Delivery system for drinks
US20160044955A1 (en) * 2014-08-13 2016-02-18 R.J. Reynolds Tobacco Company Smokeless tobacco products
US10959456B2 (en) 2014-09-12 2021-03-30 R.J. Reynolds Tobacco Company Nonwoven pouch comprising heat sealable binder fiber
FR3029103B1 (en) 2014-11-27 2018-02-16 Societe Industrielle Limousine D'application Biologique SOLUBLE ADHESIVE DRESSING BASED ON MINERALS
US20160157515A1 (en) 2014-12-05 2016-06-09 R.J. Reynolds Tobacco Company Smokeless tobacco pouch
CA2969466A1 (en) 2014-12-09 2016-06-16 Monosolrx Llc Linear polysaccharide based film products
US9956323B2 (en) 2014-12-18 2018-05-01 Cook Medical Technologies Llc Medical devices for local bioactive delivery
EP3061501A1 (en) 2015-02-27 2016-08-31 Rottapharm Ltd. Composition for the treatment of acne
US20160339086A1 (en) * 2015-05-19 2016-11-24 Suzy Cohen Compositions and methods for treating thyroid disease
USD773313S1 (en) 2015-06-23 2016-12-06 Nicholas J. Singer Package
EP3117825A1 (en) 2015-07-16 2017-01-18 Rottapharm S.p.A. Oral formulation comprising berberine and morus alba extract
US11103732B1 (en) * 2015-10-17 2021-08-31 James D. Welch Method of improving the condition of teeth
US10342646B2 (en) * 2015-10-17 2019-07-09 James D. Welch Method of, and system for smoothing teeth
US10532046B2 (en) 2015-12-03 2020-01-14 Niconovum Usa, Inc. Multi-phase delivery compositions and products incorporating such compositions
US20170165252A1 (en) 2015-12-10 2017-06-15 Niconovum Usa Inc. Protein-enriched therapeutic composition
US10499684B2 (en) 2016-01-28 2019-12-10 R.J. Reynolds Tobacco Company Tobacco-derived flavorants
US11154087B2 (en) 2016-02-02 2021-10-26 R.J. Reynolds Tobacco Company Method for preparing flavorful compounds isolated from black liquor and products incorporating the flavorful compounds
US10265362B2 (en) 2016-04-12 2019-04-23 Scott Schaneville Ingestible films having substances from hemp or cannabis
US10702590B2 (en) 2016-04-12 2020-07-07 Script Essentials, Llc Compositions and methods for treating thyroid disease
US11273131B2 (en) 2016-05-05 2022-03-15 Aquestive Therapeutics, Inc. Pharmaceutical compositions with enhanced permeation
CN109310646A (en) 2016-05-05 2019-02-05 阿奎斯蒂弗医疗股份有限公司 Enhance the adrenaline composition of delivering
JP2018000402A (en) * 2016-06-30 2018-01-11 静岡県 Tongue cover
JP2019524709A (en) * 2016-07-05 2019-09-05 グラクソスミスクライン・コンシューマー・ヘルスケア・ホールディングス・ユーエス・リミテッド・ライアビリティ・カンパニーGlaxosmithkline Consumer Healthcare Holdings (Us) Llc Oral dosage form with immediate release outer coating
WO2018022516A1 (en) * 2016-07-25 2018-02-01 Olyxir, Llc Olive leaf powder (olp) strips
TWI728172B (en) 2016-08-18 2021-05-21 美商愛戴爾製藥股份有限公司 Methods of treating eosinophilic esophagitis
MX2019005160A (en) 2016-11-15 2019-10-15 Klaria Pharma Holding Ab Pharmaceutical formulation.
US9579292B1 (en) 2016-11-21 2017-02-28 Karl Wei Cao Film forming hard capsule solution
US9700518B1 (en) 2016-11-21 2017-07-11 Karl Wei Cao Dip molding process for the manufacture of hard capsule shells
EP3565642A1 (en) * 2017-01-09 2019-11-13 The Procter and Gamble Company Barrier patch with soluble film and methods of improving skin appearance
JP6893650B2 (en) * 2017-02-24 2021-06-23 学校法人福岡大学 Release-controlled film containing water-soluble polysaccharides as the main component
US11091446B2 (en) 2017-03-24 2021-08-17 R.J. Reynolds Tobacco Company Methods of selectively forming substituted pyrazines
US10470487B2 (en) 2017-04-06 2019-11-12 R.J. Reynolds Tobacco Company Smoke treatment
CN110678555B (en) 2017-04-14 2023-10-13 比利时胶囊公司 Method for preparing pullulan
US11576870B2 (en) 2017-04-14 2023-02-14 Capsugel Belgium Nv Pullulan capsules
DE102017112527B4 (en) 2017-06-07 2019-01-03 Lts Lohmann Therapie-Systeme Ag Fast disintegrating foam wafers with a high basis weight
GB201709141D0 (en) 2017-06-08 2017-07-26 Klaria Pharma Holding Ab Pharmaceutical formulation
KR102182559B1 (en) 2017-09-08 2020-11-24 인시그니스 쎄라퓨틱스, 인코포레이티드 How to use difibephrine
CN111372555A (en) 2017-11-21 2020-07-03 3M创新有限公司 Water-in-bag plant-based oil emulsion for oral cavity and use method thereof
DE102017127434A1 (en) 2017-11-21 2019-05-23 Lts Lohmann Therapie-Systeme Ag Pocket-shaped oral-release films with high drug loading
JP7341143B2 (en) 2017-12-20 2023-09-08 スリーエム イノベイティブ プロパティズ カンパニー Oral composition and method of use
WO2019123261A2 (en) 2017-12-20 2019-06-27 3M Innovative Properties Company Oral compositions and methods of use
JP7110355B2 (en) 2018-01-26 2022-08-01 ザ プロクター アンド ギャンブル カンパニー Water soluble unit dose articles containing enzymes
JP7127135B2 (en) 2018-01-26 2022-08-29 ザ プロクター アンド ギャンブル カンパニー Water soluble products and related processes
US20190233785A1 (en) 2018-01-26 2019-08-01 The Procter & Gamble Company Water-soluble unit dose articles comprising perfume
US11053466B2 (en) 2018-01-26 2021-07-06 The Procter & Gamble Company Water-soluble unit dose articles comprising perfume
WO2019168829A1 (en) 2018-02-27 2019-09-06 The Procter & Gamble Company A consumer product comprising a flat package containing unit dose articles
WO2019239356A1 (en) 2018-06-15 2019-12-19 R. J. Reynolds Tobacco Company Purification of nicotine
GB2575625A (en) 2018-06-22 2020-01-22 Church & Dwight Co Inc Oral care compositions comprising benzocaine and mucoadhesive thin films formed therefrom
WO2020010173A1 (en) * 2018-07-06 2020-01-09 Kansas State University Research Foundation Lipid nanoemulsion-doped antimicrobial packaging films
US10982176B2 (en) 2018-07-27 2021-04-20 The Procter & Gamble Company Process of laundering fabrics using a water-soluble unit dose article
US20200196658A1 (en) 2018-12-20 2020-06-25 R.J. Reynolds Tobacco Company Method for whitening tobacco
DE102019100483A1 (en) 2019-01-10 2020-07-16 Lts Lohmann Therapie-Systeme Ag Oral thin film
CN113748195B (en) 2019-01-28 2024-01-19 宝洁公司 Recyclable, renewable or biodegradable packaging
WO2020180608A1 (en) 2019-03-01 2020-09-10 Insignis Therapeutics, Inc. Dipivefrin orally disintegrating tablet formulations
EP3712237A1 (en) 2019-03-19 2020-09-23 The Procter & Gamble Company Fibrous water-soluble unit dose articles comprising water-soluble fibrous structures
KR20200117411A (en) * 2019-04-04 2020-10-14 (주)지웰바이오 Antibacterial Composition for Inhibiting Oral Bacteria and orally disintegrating film
US11213062B2 (en) 2019-05-09 2022-01-04 American Snuff Company Stabilizer for moist snuff
CA3134222C (en) 2019-06-28 2024-01-16 The Procter & Gamble Company Dissolvable solid fibrous articles containing anionic surfactants
CN114173570A (en) * 2019-08-14 2022-03-11 洲际大品牌有限责任公司 Confectionery sheet products and methods of making the same
US20210068448A1 (en) 2019-09-11 2021-03-11 Nicoventures Trading Limited Method for whitening tobacco
US20210068446A1 (en) 2019-09-11 2021-03-11 R. J. Reynolds Tobacco Company Oral product with cellulosic flavor stabilizer
US20210068447A1 (en) 2019-09-11 2021-03-11 R. J. Reynolds Tobacco Company Pouched products with enhanced flavor stability
EP4027817A1 (en) 2019-09-11 2022-07-20 Nicoventures Trading Limited Alternative methods for whitening tobacco
US11369131B2 (en) 2019-09-13 2022-06-28 Nicoventures Trading Limited Method for whitening tobacco
MX2022005285A (en) 2019-10-31 2022-05-24 Nicoventures Trading Ltd Oral product and method of manufacture.
US20210169783A1 (en) 2019-12-09 2021-06-10 Nicoventures Trading Limited Oral products with controlled release
US20210169132A1 (en) 2019-12-09 2021-06-10 Nicoventures Trading Limited Oral composition including gels
US11883527B2 (en) * 2019-12-09 2024-01-30 Nicoventures Trading Limited Oral composition and method of manufacture
US20210169890A1 (en) 2019-12-09 2021-06-10 Nicoventures Trading Limited Oral composition with polymeric component
WO2021116826A1 (en) 2019-12-09 2021-06-17 Nicoventures Trading Limited Oral product comprising a cannabinoid
WO2021116842A1 (en) 2019-12-09 2021-06-17 Nicoventures Trading Limited Oral products with controlled release
US20210170031A1 (en) 2019-12-09 2021-06-10 Nicoventures Trading Limited Oral composition with nanocrystalline cellulose
WO2021116825A1 (en) 2019-12-09 2021-06-17 Nicoventures Trading Limited Oral product
BR112022010899A2 (en) 2019-12-09 2022-09-06 Nicoventures Trading Ltd ORAL PRODUCT WITH DISSOLUBLE COMPONENT
WO2021116823A1 (en) 2019-12-09 2021-06-17 Nicoventures Trading Limited Oral product
US11826462B2 (en) 2019-12-09 2023-11-28 Nicoventures Trading Limited Oral product with sustained flavor release
WO2021116895A2 (en) 2019-12-09 2021-06-17 Nicoventures Trading Limited Stimulus-responsive pouch
WO2021116824A1 (en) 2019-12-09 2021-06-17 Nicoventures Trading Limited Oral product comprising a cannabinoid
US20210169785A1 (en) 2019-12-09 2021-06-10 Nicoventures Trading Limited Oral compositions with reduced water activity
US20210169784A1 (en) 2019-12-09 2021-06-10 Nicoventures Trading Limited Buffered oral compositions
US11672862B2 (en) 2019-12-09 2023-06-13 Nicoventures Trading Limited Oral products with reduced irritation
WO2021116881A1 (en) 2019-12-09 2021-06-17 Nicoventures Trading Limited Oral product in a pourous pouch comprising a fleece material
WO2021116856A2 (en) 2019-12-09 2021-06-17 Nicoventures Trading Limited Oral products
US11872231B2 (en) 2019-12-09 2024-01-16 Nicoventures Trading Limited Moist oral product comprising an active ingredient
EP4072301A1 (en) 2019-12-09 2022-10-19 Nicoventures Trading Limited Nanoemulsion for oral use
US20210169868A1 (en) 2019-12-09 2021-06-10 Nicoventures Trading Limited Oral compositions with reduced water content
WO2021116916A1 (en) 2019-12-09 2021-06-17 Nicoventures Trading Limited Oral product with multiple flavors having different release profiles
WO2021116919A1 (en) 2019-12-09 2021-06-17 Nicoventures Trading Limited Fleece for oral product with releasable component
US20210169786A1 (en) 2019-12-09 2021-06-10 Nicoventures Trading Limited Oral composition with beet material
US20210169126A1 (en) 2019-12-09 2021-06-10 Nicoventures Trading Limited Oral composition with salt inclusion
US20210169138A1 (en) 2019-12-09 2021-06-10 Nicoventures Trading Limited Fibrous fleece material
WO2021116827A1 (en) 2019-12-09 2021-06-17 Nicoventures Trading Limited Process
WO2021116884A1 (en) 2019-12-09 2021-06-17 Nicoventures Trading Limited Layered fleece for pouched product
CA3159451A1 (en) 2019-12-09 2021-06-17 Savannah JOHNSON Pouched products with heat sealable binder
US20210169123A1 (en) 2019-12-09 2021-06-10 Nicoventures Trading Limited Pouched products with enhanced flavor stability
US11793230B2 (en) 2019-12-09 2023-10-24 Nicoventures Trading Limited Oral products with improved binding of active ingredients
US11617744B2 (en) 2019-12-09 2023-04-04 Nico Ventures Trading Limited Moist oral compositions
US11712059B2 (en) 2020-02-24 2023-08-01 Nicoventures Trading Limited Beaded tobacco material and related method of manufacture
WO2021250516A1 (en) 2020-06-08 2021-12-16 Nicoventures Trading Limited Effervescent oral composition comprising an active ingredient
EP4181912A1 (en) 2020-07-15 2023-05-24 Schabar Research Associates LLC Unit oral dose compositions composed of ibuprofen and famotidine for the treatment of acute pain and the reduction of the severity and/or risk of heartburn
CA3124579A1 (en) 2020-07-15 2022-01-15 Schabar Research Associates Llc Unit oral dose compositions composed of naproxen sodium and famotidine for the treatment of acute pain and the reduction of the severity of heartburn and/or the risk of heartburn
CN115867357A (en) 2020-07-31 2023-03-28 宝洁公司 Water-soluble fiber pouch containing spherulites for hair care
GB202013491D0 (en) 2020-08-27 2020-10-14 Nicoventures Holdings Ltd Oral Product
US11937626B2 (en) 2020-09-04 2024-03-26 Nicoventures Trading Limited Method for whitening tobacco
CN112076165B (en) * 2020-09-08 2022-05-13 北京哈三联科技有限责任公司 Orally disintegrating tablet capable of freshening breath and preparation method thereof
US20240008522A1 (en) 2020-11-18 2024-01-11 Nicoventures Trading Limited Oral products
EP4247331A1 (en) 2020-11-18 2023-09-27 BioPharma Synergies, S. L. Orodispersible powder composition comprising an antihistamine compound
US20220232881A1 (en) 2021-01-28 2022-07-28 Nicoventures Trading Limited Method for sealing pouches
EP4326095A1 (en) 2021-04-22 2024-02-28 Nicoventures Trading Limited Orally dissolving films
EP4329522A1 (en) 2021-04-30 2024-03-06 Nicoventures Trading Limited Oral products with high-density load
US20220354155A1 (en) 2021-04-30 2022-11-10 Nicoventures Trading Limited Multi-compartment oral pouched product
WO2022234522A1 (en) 2021-05-06 2022-11-10 Nicoventures Trading Limited Oral compositions and related methods for reducing throat irritation
WO2022264066A1 (en) 2021-06-16 2022-12-22 Nicoventures Trading Limited Pouched product comprising dissolvable composition
WO2022269556A1 (en) 2021-06-25 2022-12-29 Nicoventures Trading Limited Oral products and method of manufacture
US20230138306A1 (en) 2021-09-30 2023-05-04 Nicoventures Trading Limited Oral product with a basic amine and an ion pairing agent
FR3128880A1 (en) * 2021-11-10 2023-05-12 Strand Cosmetics Europe WATER SOLUBLE FILM FOR TOPICAL APPLICATION
US20230148660A1 (en) 2021-11-15 2023-05-18 Nicoventures Trading Limited Products with enhanced sensory characteristics
US20230148652A1 (en) 2021-11-15 2023-05-18 Nicoventures Trading Limited Oral products with nicotine-polymer complex
US20230309603A1 (en) 2022-03-31 2023-10-05 R.J. Reynolds Tobacco Company Agglomerated botanical material for oral products
WO2023194959A1 (en) 2022-04-06 2023-10-12 Nicoventures Trading Limited Pouched products with heat sealable binder
WO2023222213A1 (en) 2022-05-18 2023-11-23 Symrise Ag Antimicrobial mixtures
WO2023248187A1 (en) 2022-06-24 2023-12-28 Nicoventures Trading Limited Oral composition comprising a receptor modulator

Family Cites Families (95)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB1142325A (en) 1965-05-14 1969-02-05 Higham Stanley Russell Means for administering drugs
US3492131A (en) 1966-04-18 1970-01-27 Searle & Co Peptide sweetening agents
DE2012775C3 (en) 1970-03-18 1973-10-04 V.P. Variopharm Gmbh Herstellung Und Vertrieb Pharmazeutischer, Kosmetischer Und Chemischer Erzeugnisse, 6656 Einoed Ointment foils and process for their manufacture
US3784390A (en) 1971-07-23 1974-01-08 Hayashibara Biochem Lab Shaped bodies of pullulan and their use
US4197289A (en) 1975-12-15 1980-04-08 Hoffmann-La Roche Inc. Novel dosage forms
JPS59111817A (en) * 1982-12-11 1984-06-28 Hayashibara Biochem Lab Inc Manufacture of pullulan self-supporting film
US4562020A (en) * 1982-12-11 1985-12-31 Kabushiki Kaisha Hayashibara Seibutsu Kagaku Kenkyujo Process for producing self-supporting glucan film
US4795436A (en) 1983-11-14 1989-01-03 Bio-Mimetics, Inc. Bioadhesive composition and method of treatment therewith
JPS60219238A (en) 1984-04-14 1985-11-01 Hayashibara Biochem Lab Inc Formed product containing slowly disintegrating pullulan and its production
EP0161681A3 (en) 1984-05-17 1987-04-29 Mitsubishi Acetate Co., Ltd. Gel plate and process for preparing same
US4843098A (en) * 1985-02-05 1989-06-27 Warner-Lambert Company Ingestible aggregate and delivery system prepared therefrom
DE3532860C1 (en) * 1985-09-14 1987-03-12 Blendax Werke Schneider Co Oral hygiene products
JPH0653657B2 (en) 1985-09-26 1994-07-20 サンスタ−株式会社 Bath agent
JPH07553B2 (en) 1985-12-09 1995-01-11 佐藤製薬株式会社 Film preparation
IL78826A (en) 1986-05-19 1991-05-12 Yissum Res Dev Co Precursor composition for the preparation of a biodegradable implant for the sustained release of an active material and such implants prepared therefrom
CA1313620C (en) 1986-08-08 1993-02-16 Yasunobu Okada Oral drug delivery systems
EP0256611A1 (en) 1986-08-08 1988-02-24 Squibb Japan Inc. Oral drug delivery systems
JPS6359855A (en) 1986-08-29 1988-03-15 Jun Kawai Edible film
DE3630603A1 (en) 1986-09-09 1988-03-10 Desitin Arzneimittel Gmbh PHARMACEUTICAL AND DOSAGE FORM FOR MEDICINAL ACTIVE SUBSTANCES, REAGENTS OR THE LIKE, AND METHOD FOR THE PRODUCTION THEREOF
JPH0739508B2 (en) 1986-11-11 1995-05-01 株式会社林原生物化学研究所 Pullulan / polyethylene glycol aggregate, its production method and use
US4923394A (en) * 1986-11-19 1990-05-08 Nippon Tansan Gas Co., Ltd. Portable torch
US4851394A (en) 1986-12-30 1989-07-25 Uni Colloid Kabushiki Kaisha Glucomannan/polyhydric alcohol composition and film prepared therefrom
JPS63250319A (en) 1987-04-06 1988-10-18 Fujimoto Seiyaku Kk Pharmaceutical preparation suitable in oral cavity
JPS63250318A (en) 1987-04-06 1988-10-18 Fujimoto Seiyaku Kk Pharmaceutical preparation suitable in oral cavity
US4820506A (en) 1987-05-01 1989-04-11 Research Foundation, State University Of New York Salivary stimulant
JPS63280014A (en) 1987-05-12 1988-11-17 Sekisui Chem Co Ltd Plaster composition for bad breath prevention
JPS63296655A (en) 1987-05-29 1988-12-02 Toppan Printing Co Ltd Production of edible sheet
US4975426A (en) * 1987-06-08 1990-12-04 Analgesic Associates Cough/cold mixtures comprising non-sedating antihistamine drugs
JP2642354B2 (en) 1987-06-11 1997-08-20 株式会社 三和化学研究所 Manufacturing method of sustained release buccal
JPS63310818A (en) 1987-06-12 1988-12-19 Sato Seiyaku Kk Sheet preparation to be applied to oral mucosa
JPH01160455A (en) 1987-12-17 1989-06-23 Yoshikawa Kikai Seisakusho:Kk Feeding method of lump-like cake material and device therefor
CN1036967A (en) * 1988-02-04 1989-11-08 武田药品工业株式会社 Edible film
US5047244A (en) 1988-06-03 1991-09-10 Watson Laboratories, Inc. Mucoadhesive carrier for delivery of therapeutical agent
DE3827561C1 (en) * 1988-08-13 1989-12-28 Lts Lohmann Therapie-Systeme Gmbh & Co Kg, 5450 Neuwied, De
JPH0259513A (en) * 1988-08-24 1990-02-28 Kiyuukiyuu Yakuhin Kogyo Kk Oral cavity mucosa-attaching type halitosis-preventing agent
US5089307A (en) * 1989-05-23 1992-02-18 Mitsubishi Rayon Co., Ltd. Edible film and method of making same
US5354551A (en) 1989-10-14 1994-10-11 Desitin Arzneimittel Gmbh Oral and dental hygiene preparation
US5284659A (en) * 1990-03-30 1994-02-08 Cherukuri Subraman R Encapsulated flavor with bioadhesive character in pressed mints and confections
DE4018247A1 (en) 1990-06-07 1991-12-12 Lohmann Therapie Syst Lts MANUFACTURING METHOD FOR QUICK-DISINFITTING FILM-SHAPED PHARMACEUTICAL FORMS
GB9017800D0 (en) 1990-08-14 1990-09-26 Unilever Plc Moisture barrier and its preparation
JPH04117242A (en) * 1990-09-05 1992-04-17 Fuji Oil Co Ltd Production of nonfusible film
US5185153A (en) * 1990-10-04 1993-02-09 The Research Foundation Of The State University Of New York Agents effecting the lysis of oral bacteria
JP2785080B2 (en) 1991-02-27 1998-08-13 日清製油株式会社 Bath composition
TW209174B (en) * 1991-04-19 1993-07-11 Takeda Pharm Industry Co Ltd
JPH051198A (en) 1991-06-26 1993-01-08 Japan Happy:Kk Water-soluble film
US5141961A (en) * 1991-06-27 1992-08-25 Richrdson-Vicks Inc. Process for solubilizing difficulty soluble pharmaceutical actives
JPH05236885A (en) 1991-07-17 1993-09-17 Tazawa Toshihiko Flavoring and refreshing food formed into film
JPH0541602A (en) 1991-08-06 1993-02-19 Fujitsu General Ltd Primary radiator in common use with circularly polarized wave and linearly polarized wave
US5188822A (en) * 1991-08-07 1993-02-23 Chesebrough-Pond's Usa Co., Division Of Conopco Inc. Oral compositions containing an aminosilicone and a lipophilic compound
ES2124739T3 (en) 1991-08-23 1999-02-16 Gillette Co SUSTAINED RELEASE MATRICES FOR DENTAL USE.
US5580578A (en) * 1992-01-27 1996-12-03 Euro-Celtique, S.A. Controlled release formulations coated with aqueous dispersions of acrylic polymers
JP3232488B2 (en) 1992-08-20 2001-11-26 株式会社林原生物化学研究所 High content of pullulan, its production method and use
US5286502A (en) * 1992-04-21 1994-02-15 Wm. Wrigley Jr. Company Use of edible film to prolong chewing gum shelf life
US5411945A (en) 1992-08-29 1995-05-02 Kabushiki Kaisha Hayashibara Seibutsu Kagaku Kenkyujo Pullulan binder and its uses
WO1995005416A2 (en) * 1993-08-19 1995-02-23 Cygnus Therapeutic Systems Water-soluble pressure-sensitive mucoadhesive and devices provided therewith for emplacement in a mucosa-lined body cavity
US5536263A (en) 1994-03-30 1996-07-16 Lectec Corporation Non-occulusive adhesive patch for applying medication to the skin
JP3313244B2 (en) * 1994-08-11 2002-08-12 三井化学株式会社 Salicylate resin and method for producing the same
US5529783A (en) * 1994-12-19 1996-06-25 Mcneil-Ppc, Inc. Rotor granulation and coating of acetaminophen, pseudoephedrine, chlorpheniramine, and, optionally dextromethorphan
US5641512A (en) * 1995-03-29 1997-06-24 The Procter & Gamble Company Soft gelatin capsule compositions
CN1190342A (en) 1995-06-05 1998-08-12 白山口腔技术有限公司 Oral care ultramulsion based product
EP0750905B1 (en) 1995-06-27 2003-01-02 Kao Corporation Patch comprising water soluble adhesive sheet
JPH09124512A (en) 1995-10-26 1997-05-13 Res Inst For Prod Dev Water-soluble medicine-pullulan combination preparation for targeting liver
JP2791317B2 (en) 1995-12-26 1998-08-27 株式会社三和化学研究所 Multilayer film preparation
AU1533697A (en) * 1996-01-24 1997-08-20 Warner-Lambert Company Peroxide/essential oils containing mouthwash compositions and two-part mouthwash systems
US5912007A (en) 1996-02-29 1999-06-15 Warner-Lambert Company Delivery system for the localized administration of medicaments to the upper respiratory tract and methods for preparing and using same
EP0803243B1 (en) 1996-04-24 2003-03-19 Pfizer Inc. Cyclodextrins and phenolic compounds in dental products
ATE400299T1 (en) * 1996-07-12 2008-07-15 Daiichi Seiyaku Co RAPIDLY DEGRADING, PRESSURE-FORMED MATERIALS AND THE PROCESS FOR THEIR PRODUCTION
US6121315A (en) * 1996-09-20 2000-09-19 Warner-Lambert Company Oral compositions containing a zinc compound
DE19646392A1 (en) * 1996-11-11 1998-05-14 Lohmann Therapie Syst Lts Preparation for use in the oral cavity with a layer containing pressure-sensitive adhesive, pharmaceuticals or cosmetics for dosed delivery
DE19652188C2 (en) 1996-12-16 2002-02-14 Lohmann Therapie Syst Lts Flat drug preparation for application and release of buprenorphine or a pharmacologically comparable substance in the oral cavity and process for its preparation
DE19652268C2 (en) 1996-12-16 2000-06-29 Lohmann Therapie Syst Lts Medicinal preparation for the release of apomorphine in the oral cavity
JPH10179451A (en) 1996-12-20 1998-07-07 Aisin Seiki Co Ltd Raising and lowering device for toilet seat with hot water washing device
JPH10179045A (en) 1996-12-25 1998-07-07 Osaka Kagaku Gokin Kk Sheet-like edible molding
US5885594A (en) * 1997-03-27 1999-03-23 The Procter & Gamble Company Oral compositions having enhanced mouth-feel
US6136297A (en) 1997-06-06 2000-10-24 The Procter & Gamble Company Delivery system for an oral care substance using a strip of material having low flexural stiffness
JPH1160455A (en) * 1997-06-13 1999-03-02 Yuusuke Nonomura Controlling agent for bacterial flora including preventing agent for dental caries and controlling
GB2328443B (en) * 1997-08-21 2001-09-05 Reckitt & Colmann Prod Ltd In situ formation of pharmaceutically acceptable polymeric material
JP3460538B2 (en) 1997-10-08 2003-10-27 救急薬品工業株式会社 Fast dissolving film preparation
WO1999032075A1 (en) * 1997-12-22 1999-07-01 Warner-Lambert Company Compositions for inhibiting gingivitis
US6432442B1 (en) * 1998-02-23 2002-08-13 Mcneil-Ppc, Inc. Chewable product
US6132702A (en) * 1998-02-27 2000-10-17 The Procter & Gamble Company Oral care compositions comprising chlorite and methods
US6596298B2 (en) * 1998-09-25 2003-07-22 Warner-Lambert Company Fast dissolving orally comsumable films
US20030211136A1 (en) * 1998-09-25 2003-11-13 Neema Kulkarni Fast dissolving orally consumable films containing a sweetener
US6231957B1 (en) * 1999-05-06 2001-05-15 Horst G. Zerbe Rapidly disintegrating flavor wafer for flavor enrichment
US7067116B1 (en) * 2000-03-23 2006-06-27 Warner-Lambert Company Llc Fast dissolving orally consumable solid film containing a taste masking agent and pharmaceutically active agent at weight ratio of 1:3 to 3:1
US6372252B1 (en) * 2000-04-28 2002-04-16 Adams Laboratories, Inc. Guaifenesin sustained release formulation and tablets
US20020131990A1 (en) 2000-11-30 2002-09-19 Barkalow David G. Pullulan free edible film compositions and methods of making the same
US6656493B2 (en) 2001-07-30 2003-12-02 Wm. Wrigley Jr. Company Edible film formulations containing maltodextrin
CN1571654A (en) 2001-08-17 2005-01-26 史密丝克莱恩比彻姆有限公司 Oral care substance delivery strip
US6419903B1 (en) * 2001-08-20 2002-07-16 Colgate Palmolive Company Breath freshening film
DK2332523T4 (en) 2001-10-12 2022-02-21 Aquestive Therapeutics Inc Uniform films for rapid-dissolution dosage form containing taste-masking preparations
ES2735512T3 (en) 2001-10-12 2019-12-19 Aquestive Therapeutics Inc Thin film with uniform non-self-aggregating heterogeneity, process for its production and drug delivery systems made from it
CA2473975C (en) 2001-10-12 2011-05-03 Monosolrx Llc Glucan based film delivery systems
US20030224090A1 (en) 2002-02-11 2003-12-04 Edizone, Lc Snacks of orally soluble edible films
WO2005074894A1 (en) * 2004-01-30 2005-08-18 Corium International Rapidly dissolving film for delivery of an active agent

Cited By (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US11571450B2 (en) 2020-06-17 2023-02-07 Psilo Scientific Ltd Aqueous extraction of psychoactive compounds from psilocybin fungus
US11642385B2 (en) 2020-06-17 2023-05-09 Psilo Scientific Ltd. Basic extraction of psychoactive compounds from psychoactive organisms
WO2022140841A1 (en) * 2020-12-28 2022-07-07 Psilo Scientific Ltd Transmucosal psychoactive alkaloid composition and preparation thereof
US11786506B2 (en) 2020-12-28 2023-10-17 Psilo Scientific Ltd Transmucosal psychoactive alkaloid composition and preparation thereof
US11957659B2 (en) 2020-12-28 2024-04-16 Psilo Scientific Ltd. Transmucosal dephosphorylated psychoactive alkaloid composition and preparation thereof

Also Published As

Publication number Publication date
CO4930288A1 (en) 2000-06-27
EP1676557A3 (en) 2006-09-06
US6923981B2 (en) 2005-08-02
PA8482401A1 (en) 2001-12-14
JP2002525306A (en) 2002-08-13
WO2000018365A2 (en) 2000-04-06
KR20010075347A (en) 2001-08-09
PE20000972A1 (en) 2000-10-02
DE69931380D1 (en) 2006-06-22
ES2260961T3 (en) 2006-11-01
US7025983B2 (en) 2006-04-11
US20030054034A1 (en) 2003-03-20
US20040136922A1 (en) 2004-07-15
UY25728A1 (en) 1999-11-17
TWI286943B (en) 2007-09-21
US7491406B2 (en) 2009-02-17
DK1115372T3 (en) 2006-09-18
CN101810547A (en) 2010-08-25
US20050031675A1 (en) 2005-02-10
GT199900164AA (en) 2001-03-16
TWI238067B (en) 2005-08-21
US20010022964A1 (en) 2001-09-20
PT1115372E (en) 2006-07-31
SI1115372T1 (en) 2006-10-31
US20060039953A1 (en) 2006-02-23
EE200100186A (en) 2002-08-15
HK1040619A1 (en) 2002-06-21
ID27740A (en) 2001-04-26
US7867509B2 (en) 2011-01-11
TW200528146A (en) 2005-09-01
US20030206941A1 (en) 2003-11-06
BR9914064A (en) 2001-06-19
NO20011476L (en) 2001-03-22
ZA200101706B (en) 2003-05-28
ATE326203T1 (en) 2006-06-15
EP1115372A2 (en) 2001-07-18
US7407669B2 (en) 2008-08-05
US20090163530A1 (en) 2009-06-25
US6596298B2 (en) 2003-07-22
IL141919A0 (en) 2002-03-10
DE69931380T2 (en) 2007-05-31
EP1115372B1 (en) 2006-05-17
CY1105213T1 (en) 2010-03-03
IL192633A0 (en) 2009-02-11
AU771862B2 (en) 2004-04-01
GT199900164A (en) 2001-03-16
WO2000018365A3 (en) 2000-11-16
CO4940396A1 (en) 2000-07-24
CA2339353C (en) 2006-01-24
US20030008008A1 (en) 2003-01-09
BR9917781B1 (en) 2011-11-29
BR9914064B1 (en) 2011-08-23
NO20011476D0 (en) 2001-03-22
CN1321080A (en) 2001-11-07
EP1676557A2 (en) 2006-07-05
AR020513A1 (en) 2002-05-15
AU6059399A (en) 2000-04-17
AR064901A2 (en) 2009-05-06

Similar Documents

Publication Publication Date Title
CA2339353A1 (en) Fast dissolving orally consumable films
CA2520986A1 (en) Physiological compatible film
WO2004058217A3 (en) Water-soluble film for oral use
JP4817721B2 (en) Composition applied to mouth for releasing nicotine as active substance in oral cavity and method for producing the same
AU1044902A (en) Pectin film compositions
WO2003011259A8 (en) Improved edible film formulations containing maltodextrin
CA2371940A1 (en) Pregelatinized starch in a controlled release formulation
ATE444738T1 (en) IMPROVED EDIBLE FILM FORMULATIONS WITH MALTODEXTRIN
WO1996015786A3 (en) Oral compositions containing ondansetron
DE102005033942A1 (en) Non-spitting, oral, fast-disintegrating film for antiemetic or antimigraine
CA2377174A1 (en) Oral administration forms for administering a fixed tramadol and diclofenac combination
EP0966966A3 (en) Nefazodone dosage form
ATE287264T1 (en) ORAL MEDICINAL PRODUCTS CONTAINING BUPRENORPHINE
GB2574878A (en) Oral compositions and mucoadhesive thin films formed therefrom
IT1240843B (en) XANTHINIC DERIVATIVES 1-7 SUBSTITUTED FOR ANTIASMATIC ACTIVITY, THEIR PHYSIOLOGICALLY ACCEPTABLE SALTS, THEIR PHARMACEUTICAL COMPOSITIONS AND PROCEDURE FOR THEIR PREPARATION.
JP2000063268A (en) Oral mucosa adhesion-type controlled release troche and periodontal disease therapeutic agent
EP1051993A3 (en) 5HT1 receptor agonists and either a COX-2 inhibitor or NSAID for the treatment of migraine
ECSP993152A (en) ORALLY CONSUMABLE FILMS THAT DISSOLVE QUICKLY
US20070292531A1 (en) Composition for oral use and methods for application of same
TH64450A (en) An oral edible film that dissolves quickly. Which contains ion exchange resins as a flavoring agent.

Legal Events

Date Code Title Description
EEER Examination request
MKEX Expiry

Effective date: 20190923