CA2339353A1 - Fast dissolving orally consumable films - Google Patents

Fast dissolving orally consumable films Download PDF

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Publication number
CA2339353A1
CA2339353A1 CA002339353A CA2339353A CA2339353A1 CA 2339353 A1 CA2339353 A1 CA 2339353A1 CA 002339353 A CA002339353 A CA 002339353A CA 2339353 A CA2339353 A CA 2339353A CA 2339353 A1 CA2339353 A1 CA 2339353A1
Authority
CA
Canada
Prior art keywords
films
disclosed
fast dissolving
orally consumable
pullulan
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Granted
Application number
CA002339353A
Other languages
French (fr)
Other versions
CA2339353C (en
Inventor
Sau-Hung Spence Leung
Robert S. Leone
Lori Dee Kumar
Neema Kulkarni
Albert F. Sorg
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Warner Lambert Co LLC
Original Assignee
Warner-Lambert Company
Sau-Hung Spence Leung
Robert S. Leone
Lori Dee Kumar
Neema Kulkarni
Albert F. Sorg
Warner-Lambert Company Llc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Warner-Lambert Company, Sau-Hung Spence Leung, Robert S. Leone, Lori Dee Kumar, Neema Kulkarni, Albert F. Sorg, Warner-Lambert Company Llc filed Critical Warner-Lambert Company
Priority to CA002520986A priority Critical patent/CA2520986C/en
Publication of CA2339353A1 publication Critical patent/CA2339353A1/en
Application granted granted Critical
Publication of CA2339353C publication Critical patent/CA2339353C/en
Anticipated expiration legal-status Critical
Expired - Lifetime legal-status Critical Current

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Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/70—Web, sheet or filament bases ; Films; Fibres of the matrix type containing drug
    • A—HUMAN NECESSITIES
    • A23—FOODS OR FOODSTUFFS; TREATMENT THEREOF, NOT COVERED BY OTHER CLASSES
    • A23G—COCOA; COCOA PRODUCTS, e.g. CHOCOLATE; SUBSTITUTES FOR COCOA OR COCOA PRODUCTS; CONFECTIONERY; CHEWING GUM; ICE-CREAM; PREPARATION THEREOF
    • A23G3/00—Sweetmeats; Confectionery; Marzipan; Coated or filled products
    • A23G3/34—Sweetmeats, confectionery or marzipan; Processes for the preparation thereof
    • A23G3/50—Sweetmeats, confectionery or marzipan; Processes for the preparation thereof characterised by shape, structure or physical form, e.g. products with supported structure
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K8/00—Cosmetics or similar toiletry preparations
    • A61K8/02—Cosmetics or similar toiletry preparations characterised by special physical form
    • A61K8/0208—Tissues; Wipes; Patches
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K8/00—Cosmetics or similar toiletry preparations
    • A61K8/02—Cosmetics or similar toiletry preparations characterised by special physical form
    • A61K8/0216—Solid or semisolid forms
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
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    • A61K8/19—Cosmetics or similar toiletry preparations characterised by the composition containing inorganic ingredients
    • A61K8/20—Halogens; Compounds thereof
    • A61K8/21—Fluorides; Derivatives thereof
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
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    • A61K8/18—Cosmetics or similar toiletry preparations characterised by the composition
    • A61K8/30—Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds
    • A61K8/33—Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds containing oxygen
    • A61K8/34—Alcohols
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
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    • A61K8/30—Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds
    • A61K8/33—Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds containing oxygen
    • A61K8/34—Alcohols
    • A61K8/347—Phenols
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
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    • A61K8/37—Esters of carboxylic acids
    • A—HUMAN NECESSITIES
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    • A61K8/40—Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds containing nitrogen
    • A61K8/41—Amines
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    • A—HUMAN NECESSITIES
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    • A61K8/30—Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds
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    • A61K8/72—Cosmetics or similar toiletry preparations characterised by the composition containing organic macromolecular compounds
    • A61K8/73—Polysaccharides
    • A61K8/731—Cellulose; Quaternized cellulose derivatives
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    • A—HUMAN NECESSITIES
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    • A61K8/8129—Compositions of homopolymers or copolymers of compounds having one or more unsaturated aliphatic radicals, each having only one carbon-to-carbon double bond, and at least one being terminated by an alcohol, ether, aldehydo, ketonic, acetal or ketal radical; Compositions of hydrolysed polymers or esters of unsaturated alcohols with saturated carboxylic acids; Compositions of derivatives of such polymers, e.g. polyvinylmethylether
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    • A61K8/922—Oils, fats or waxes; Derivatives thereof, e.g. hydrogenation products thereof of vegetable origin
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    • A61K9/0056—Mouth soluble or dispersible forms; Suckable, eatable, chewable coherent forms; Forms rapidly disintegrating in the mouth; Lozenges; Lollipops; Bite capsules; Baked products; Baits or other oral forms for animals
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    • A61K9/0053—Mouth and digestive tract, i.e. intraoral and peroral administration
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    • A61K9/20—Pills, tablets, discs, rods
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Abstract

Physiologically acceptable films, including edible films, are disclosed. The films include a water soluble film-forming polymer such as pullulan. Edible films are disclosed that include pullulan and antimicrobially effective amounts of the essential oils thymol, methyl salicylate, eucalyptol and menthol. The edible films are effective at killing the plaque-producing germs that cause dental plaque, gingivitis and bad breath. The film can also contain pharmaceutically acitve agents.
Methods for producing the films are also disclosed.
CA002339353A 1998-09-25 1999-09-23 Fast dissolving orally consumable films Expired - Lifetime CA2339353C (en)

Priority Applications (1)

Application Number Priority Date Filing Date Title
CA002520986A CA2520986C (en) 1998-09-25 1999-09-23 Physiological compatible film

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US10179898P 1998-09-25 1998-09-25
US60/101,798 1998-09-25
PCT/US1999/022115 WO2000018365A2 (en) 1998-09-25 1999-09-23 Fast dissolving orally consumable films

Related Child Applications (1)

Application Number Title Priority Date Filing Date
CA002520986A Division CA2520986C (en) 1998-09-25 1999-09-23 Physiological compatible film

Publications (2)

Publication Number Publication Date
CA2339353A1 true CA2339353A1 (en) 2000-04-06
CA2339353C CA2339353C (en) 2006-01-24

Family

ID=22286467

Family Applications (1)

Application Number Title Priority Date Filing Date
CA002339353A Expired - Lifetime CA2339353C (en) 1998-09-25 1999-09-23 Fast dissolving orally consumable films

Country Status (29)

Country Link
US (8) US6596298B2 (en)
EP (2) EP1115372B1 (en)
JP (1) JP2002525306A (en)
KR (1) KR20010075347A (en)
CN (2) CN101810547A (en)
AR (2) AR020513A1 (en)
AT (1) ATE326203T1 (en)
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Cited By (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO2022140841A1 (en) * 2020-12-28 2022-07-07 Psilo Scientific Ltd Transmucosal psychoactive alkaloid composition and preparation thereof
US11571450B2 (en) 2020-06-17 2023-02-07 Psilo Scientific Ltd Aqueous extraction of psychoactive compounds from psilocybin fungus

Families Citing this family (515)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US20030211136A1 (en) * 1998-09-25 2003-11-13 Neema Kulkarni Fast dissolving orally consumable films containing a sweetener
US20030206942A1 (en) * 1998-09-25 2003-11-06 Neema Kulkarni Fast dissolving orally consumable films containing an antitussive and a mucosa coating agent
US6596298B2 (en) * 1998-09-25 2003-07-22 Warner-Lambert Company Fast dissolving orally comsumable films
EP1139793B1 (en) 1998-12-23 2009-10-14 Mount Sinai School of Medicine of New York University Inhibitors of the bitter taste response
US20040115252A1 (en) * 1999-06-25 2004-06-17 Thomas Leon Methods of treating illnesses in non-human mammals
DE60016927T2 (en) 1999-07-02 2005-12-22 The Procter & Gamble Company, Cincinnati COMPOSITIONS CONTAINING ORGANOSILOXAN RESINS FOR THE RELEASE OF MOIST MAINTENANCE MATERIALS AND FOR EXTENDING THE RELEASE
EP1204699B1 (en) * 1999-07-22 2005-06-08 Warner-Lambert Company LLC Pullulan film compositions
US7314716B2 (en) * 1999-11-19 2008-01-01 Mount Sinai School Of Medicine Gustducin γ subunit materials and methods
US7067116B1 (en) * 2000-03-23 2006-06-27 Warner-Lambert Company Llc Fast dissolving orally consumable solid film containing a taste masking agent and pharmaceutically active agent at weight ratio of 1:3 to 3:1
US6315987B1 (en) * 2000-05-10 2001-11-13 Isp Investments Inc. Polymeric delivery and release systems for oral care actives
DE10032456A1 (en) 2000-07-04 2002-01-31 Lohmann Therapie Syst Lts Rapidly disintegrating dosage form for the release of active substances in the mouth or in the body cavities
USRE44145E1 (en) 2000-07-07 2013-04-09 A.V. Topchiev Institute Of Petrochemical Synthesis Preparation of hydrophilic pressure sensitive adhesives having optimized adhesive properties
US6391886B1 (en) * 2000-12-04 2002-05-21 The Procter & Gamble Company Oral compositions having improved consumer aesthetics
DE10063945A1 (en) * 2000-12-20 2002-07-04 Henkel Kgaa Remineralizing dental adhesive film
US20060062864A1 (en) * 2000-12-28 2006-03-23 Mccleary Edward L Weight loss composition and method
US20040043013A1 (en) 2000-12-28 2004-03-04 Mccleary Edward Larry Metabolic uncoupling therapy
JP2004532814A (en) * 2001-01-09 2004-10-28 ラヴィファーム・ラボラトリーズ・インク Apparatus for local and systemic delivery of actives and method of making same
DE60218425D1 (en) 2001-01-23 2007-04-12 Beek Global Llc Van PESTICIDAL COMPOUNDS AND COMPOSITIONS
DE10107659B4 (en) 2001-02-19 2008-03-13 Lts Lohmann Therapie-Systeme Ag Mucoadhesive disintegratable drug preparation for drug administration in veterinary and human medicine
EP2324821A1 (en) * 2001-02-28 2011-05-25 Axiomedic Ltd. Oral care compositions
US8980334B2 (en) 2001-02-28 2015-03-17 Axiomedic Ltd. Double-layered absorbable solid compositions for the topical treatment of oral mucosal disorders
US20060014773A1 (en) * 2001-04-19 2006-01-19 Mccleary Edward L Mental agility lozenge, edible strip, food or drink
US20060110478A1 (en) * 2004-11-22 2006-05-25 Mccleary Edward L Delivery system and method for supporting and promoting healthy sexual function and prevention and treatment of sexual dysfunction
US20050215727A1 (en) 2001-05-01 2005-09-29 Corium Water-absorbent adhesive compositions and associated methods of manufacture and use
US8206738B2 (en) 2001-05-01 2012-06-26 Corium International, Inc. Hydrogel compositions with an erodible backing member
DE60239528D1 (en) 2001-05-01 2011-05-05 Corium International Redwood City TWO-PHASE, WATER-ABSORBING BIOADHESIVE COMPOSITION
US8541021B2 (en) 2001-05-01 2013-09-24 A.V. Topchiev Institute Of Petrochemical Synthesis Hydrogel compositions demonstrating phase separation on contact with aqueous media
US20050113510A1 (en) 2001-05-01 2005-05-26 Feldstein Mikhail M. Method of preparing polymeric adhesive compositions utilizing the mechanism of interaction between the polymer components
JP4116447B2 (en) 2001-05-01 2008-07-09 エイ．ブイ．トップチーブ インスティテュート オブ ペトロケミカル シンセシス Hydrogel composition
US8840918B2 (en) 2001-05-01 2014-09-23 A. V. Topchiev Institute of Petrochemical Synthesis, Russian Academy of Sciences Hydrogel compositions for tooth whitening
US6976647B2 (en) * 2001-06-05 2005-12-20 Elan Pharma International, Limited System and method for milling materials
US6660292B2 (en) * 2001-06-19 2003-12-09 Hf Flavoring Technology Llp Rapidly disintegrating flavored film for precooked foods
US6656493B2 (en) 2001-07-30 2003-12-02 Wm. Wrigley Jr. Company Edible film formulations containing maltodextrin
US6419903B1 (en) * 2001-08-20 2002-07-16 Colgate Palmolive Company Breath freshening film
JP5089840B2 (en) * 2001-09-25 2012-12-05 救急薬品工業株式会社 Nicotine-containing film preparation
ES2344407T3 (en) * 2001-10-09 2010-08-26 Arrow Coated Products Limited MANUFACTURING PROCEDURE OF A SOLUBLE FILM SYSTEM IN EMBEDDED WATER.
US11207805B2 (en) 2001-10-12 2021-12-28 Aquestive Therapeutics, Inc. Process for manufacturing a resulting pharmaceutical film
US7357891B2 (en) 2001-10-12 2008-04-15 Monosol Rx, Llc Process for making an ingestible film
US7425292B2 (en) 2001-10-12 2008-09-16 Monosol Rx, Llc Thin film with non-self-aggregating uniform heterogeneity and drug delivery systems made therefrom
CA2473975C (en) * 2001-10-12 2011-05-03 Monosolrx Llc Glucan based film delivery systems
US20060039958A1 (en) * 2003-05-28 2006-02-23 Monosolrx, Llc. Multi-layer films having uniform content
US20070154527A1 (en) * 2001-10-12 2007-07-05 Monosoirx, Llc Topical film compositions for delivery of actives
US10285910B2 (en) 2001-10-12 2019-05-14 Aquestive Therapeutics, Inc. Sublingual and buccal film compositions
US8900498B2 (en) 2001-10-12 2014-12-02 Monosol Rx, Llc Process for manufacturing a resulting multi-layer pharmaceutical film
US8663687B2 (en) 2001-10-12 2014-03-04 Monosol Rx, Llc Film compositions for delivery of actives
US20070281003A1 (en) 2001-10-12 2007-12-06 Fuisz Richard C Polymer-Based Films and Drug Delivery Systems Made Therefrom
US20110033542A1 (en) * 2009-08-07 2011-02-10 Monosol Rx, Llc Sublingual and buccal film compositions
US7910641B2 (en) * 2001-10-12 2011-03-22 Monosol Rx, Llc PH modulated films for delivery of actives
US20100021526A1 (en) * 2001-10-12 2010-01-28 Monosol Rx, Llc Ph modulated films for delivery of actives
US8603514B2 (en) 2002-04-11 2013-12-10 Monosol Rx, Llc Uniform films for rapid dissolve dosage form incorporating taste-masking compositions
US20190328679A1 (en) 2001-10-12 2019-10-31 Aquestive Therapeutics, Inc. Uniform films for rapid-dissolve dosage form incorporating anti-tacking compositions
US8765167B2 (en) 2001-10-12 2014-07-01 Monosol Rx, Llc Uniform films for rapid-dissolve dosage form incorporating anti-tacking compositions
US7666337B2 (en) 2002-04-11 2010-02-23 Monosol Rx, Llc Polyethylene oxide-based films and drug delivery systems made therefrom
US8900497B2 (en) 2001-10-12 2014-12-02 Monosol Rx, Llc Process for making a film having a substantially uniform distribution of components
US20030099691A1 (en) * 2001-11-16 2003-05-29 Susan Lydzinski Films containing starch
GB0128674D0 (en) * 2001-11-30 2002-01-23 Boots Co Plc Treatment of sleep disorders and the like
EP1790687A3 (en) * 2001-12-11 2007-07-25 Ceapro Inc. Cereal beta glucan compositions, methods of preparation and uses thereof
US20050031674A1 (en) * 2001-12-11 2005-02-10 Ceapro, Inc Cereal beta glucan compositions, methods of preparation and uses thereof
KR20030054221A (en) * 2001-12-24 2003-07-02 애경산업(주) Composite film composition for oral cavity and preparing method thereof
US20050003048A1 (en) * 2002-02-11 2005-01-06 Edizone, Lc Electrolyte-containing orally soluble films
US20040247746A1 (en) * 2002-02-11 2004-12-09 Edizone, Lc Delivery units of thick orally soluble polymer
US20040247744A1 (en) * 2002-02-11 2004-12-09 Edizone, Lc Vitamin-containing orally soluble films
US20030224090A1 (en) * 2002-02-11 2003-12-04 Edizone, Lc Snacks of orally soluble edible films
US20040247649A1 (en) * 2002-02-11 2004-12-09 Edizone, Lc Medicine-containing orally soluble films
US20050100640A1 (en) * 2002-02-11 2005-05-12 Pearce Tony M. Microcapsule edibles
US20030191029A1 (en) * 2002-03-28 2003-10-09 Elementis Specialties, Inc. Aqueous-based oil well drilling fluids containing high amylose starch polymers
AU2003224890A1 (en) * 2002-04-08 2003-10-27 Lavipharm Laboratories Inc. Drug-complex microparticles and methods of making/using same
US8017150B2 (en) * 2002-04-11 2011-09-13 Monosol Rx, Llc Polyethylene oxide-based films and drug delivery systems made therefrom
EP1504765B1 (en) * 2002-05-16 2015-07-22 Kyukyu Pharmaceutical Co., Ltd. Quickly soluble film preparations
DE10224607B4 (en) * 2002-06-04 2008-03-13 Lts Lohmann Therapie-Systeme Ag Film-form, disintegratable preparations for drug release and process for their preparation
JP2004018470A (en) * 2002-06-18 2004-01-22 Takasago Internatl Corp Antimicrobial perfume composition, foul breath-preventing perfume composition, and composition for oral cavity containing the compositions
US20030235613A1 (en) * 2002-06-19 2003-12-25 Cts Chemical Industries Ltd. Popping oral administration form
US20030235606A1 (en) * 2002-06-21 2003-12-25 Nussen Kenneth H. Oral hygiene products and methods of making oral hygiene products
US20030235630A1 (en) * 2002-06-21 2003-12-25 Nussen Kenneth H. Dental hygiene products and methods of making dental hygiene products
US6937455B2 (en) * 2002-07-03 2005-08-30 Kronos Advanced Technologies, Inc. Spark management method and device
US20050025719A1 (en) * 2002-06-21 2005-02-03 Nussen Kenneth H. Method and apparatus for oral hygiene products with green tea extract
US20050287231A1 (en) * 2002-06-21 2005-12-29 Nussen Kenneth H Method and apparatus for oral hygiene products with green tea extract
US7347985B2 (en) * 2002-06-25 2008-03-25 Wm. Wrigley Jr. Company Breath freshening and oral cleansing product with magnolia bark extract
US7632525B2 (en) 2002-06-25 2009-12-15 Wm. Wrigley Jr. Company Breath freshening and oral cleansing product with magnolia bark extract in combination with surface active agents
US7595065B2 (en) * 2002-06-25 2009-09-29 Wm. Wrigley Jr. Company Breath freshening and oral cleansing products with synergistic combinations of magnolia bark extract and essential oils
WO2004000235A2 (en) * 2002-06-25 2003-12-31 Wm. Wrigley Jr. Company Breath freshening and oral cleansing product with magnolia bark extract
US7150780B2 (en) * 2004-01-08 2006-12-19 Kronos Advanced Technology, Inc. Electrostatic air cleaning device
US20040013723A1 (en) * 2002-07-16 2004-01-22 PARIKH Rita M. Oral care capsules
CN1747656B (en) 2002-07-22 2011-05-04 莫诺索尔克斯有限公司 Packaging and dispensing of rapid dissolve dosage form
US20040018156A1 (en) * 2002-07-23 2004-01-29 Szeles Lori H Enzyme enhanced breath freshening film
GB0217382D0 (en) * 2002-07-26 2002-09-04 Pfizer Ltd Process for making orally consumable dosage forms
AU2002950426A0 (en) * 2002-07-29 2002-09-12 Patrick John Shanahan Anti microbial oro-dental system
AU2003281744B2 (en) * 2002-07-29 2005-03-10 Patrick John Shanahan Oral and dental composition
US7241411B2 (en) 2002-08-23 2007-07-10 Acupac Packaging, Inc. Thin film strips
US6824829B2 (en) * 2002-08-23 2004-11-30 Acupac Packaging, Inc. Process for manufacturing thin film strips
CA2495064A1 (en) * 2002-08-27 2004-03-11 Wm. Wrigley Jr. Company Breath freshening and oral cleansing product using salicylaldehyde
US20040043134A1 (en) * 2002-08-27 2004-03-04 Corriveau Christine Leclair Rolled edible thin film products and methods of making same
WO2004019802A2 (en) * 2002-08-27 2004-03-11 Wm. Wrigley Jr. Company Breath freshening and oral cleansing product using carvacrol
DE60333196D1 (en) * 2002-08-27 2010-08-12 Wrigley W M Jun Co AIRBORNE AND MOUTHPROOF PRODUCT USING CARDAMOM L
GB2408686A (en) * 2002-09-06 2005-06-08 Mars Inc Edible films having distinct regions
US20040120991A1 (en) * 2002-09-07 2004-06-24 Mars Incorporated Edible films having distinct regions
US8524200B2 (en) 2002-09-11 2013-09-03 The Procter & Gamble Company Tooth whitening products
US20050019277A1 (en) * 2002-09-11 2005-01-27 The Procter & Gamble Company Tooth whitening products
US20040052853A1 (en) * 2002-09-16 2004-03-18 Cp Kelco, U.S., Inc. Pectin films
US6916463B2 (en) 2002-09-24 2005-07-12 The Procter & Gamble Company Oral products having an aesthetic layer
JP4776233B2 (en) * 2002-11-12 2011-09-21 エラン ファーマ インターナショナル，リミティド Fast disintegrating solid formulation that is resistant to abrasion and contains pullulan
US8999372B2 (en) * 2002-11-14 2015-04-07 Cure Pharmaceutical Corporation Methods for modulating dissolution, bioavailability, bioequivalence and drug delivery profile of thin film drug delivery systems, controlled-release thin film dosage formats, and methods for their manufacture and use
US20040131662A1 (en) * 2003-11-12 2004-07-08 Davidson Robert S. Method and apparatus for minimizing heat, moisture, and shear damage to medicants and other compositions during incorporation of same with edible films
US20040191302A1 (en) 2003-03-28 2004-09-30 Davidson Robert S. Method and apparatus for minimizing heat, moisture, and shear damage to medicants and other compositions during incorporation of same with edible films
US9561182B2 (en) * 2003-08-22 2017-02-07 Cure Pharmaceutical Corporation Edible films for administration of medicaments to animals, methods for their manufacture and methods for their use for the treatment of animals
US20040136923A1 (en) * 2002-11-14 2004-07-15 Davidson R Steven Edible film for relief of cough or symptoms associated with pharyngitis
US20040096569A1 (en) * 2002-11-15 2004-05-20 Barkalow David G. Edible film products and methods of making same
EP1575554A1 (en) * 2002-12-06 2005-09-21 Monosolrx Llc Thin film delivery systems for volatile decongestants
US20040115137A1 (en) * 2002-12-17 2004-06-17 Verrall Andrew P. Water-soluble film for oral administration
WO2004058231A2 (en) * 2002-12-26 2004-07-15 University Of Manitoba Dissolving film comprising a therapeutically active agent within the film or in a pouch formed by the film
US6669929B1 (en) * 2002-12-30 2003-12-30 Colgate Palmolive Company Dentifrice containing functional film flakes
SE0302947D0 (en) * 2003-01-24 2003-11-07 Magle Ab A composition material for transmucosal delivery
WO2004066986A1 (en) * 2003-01-30 2004-08-12 Monosolrx Llc Thin film with non-self-aggregating uniform heterogeneity and drug delivery systems made therefrom
US20040228892A1 (en) * 2003-02-28 2004-11-18 Berry Craig J. Delivery system for cosmetic and skincare products
US7041311B2 (en) 2003-02-28 2006-05-09 International Flavors & Fragrances Inc. Preparation for saliva flow
AT414095B (en) * 2003-03-11 2006-09-15 Gebro Pharma Gmbh Preparation useful e.g. to treat dry mucous membrane in oral and throat area comprises medical and/or food organic substance, flavor material, mucoadhesive substance, sugar (alcohol) and carrier substance e.g. fat and/or oil
US20040180110A1 (en) * 2003-03-14 2004-09-16 Atul Mistry Chewing gum and confectionery compositions containing an endothermic agent
US20040185093A1 (en) * 2003-03-18 2004-09-23 Szymczak Christopher E. Compositions containing sucralose
MXPA05010197A (en) * 2003-03-26 2005-11-08 Procter & Gamble Rapidly dissolving edible film compositions with improved film strength and stability.
EP1605905A1 (en) * 2003-03-26 2005-12-21 The Procter & Gamble Company Rapidly dissolving edible film compositions with cellulose film forming polymers
US20040202698A1 (en) * 2003-04-02 2004-10-14 The Procter & Gamble Company Drug delivery systems comprising an encapsulated active ingredient
US20040202755A1 (en) * 2003-04-08 2004-10-14 Myers Gale D. Speckled confection pieces
JP2006524743A (en) * 2003-04-14 2006-11-02 エフ　エム　シー　コーポレーション Uniform thermoreversible alginate film and soft capsule made therefrom
US6708826B1 (en) * 2003-04-30 2004-03-23 Warner-Lambert Company, Llc Packaged supply of individual doses of a personal care product
GB0312419D0 (en) * 2003-05-30 2003-07-02 Boots Healthcare Int Ltd Use of a compound in the treatment of sleep disorders and the like, in providing refreshedness on waking and a method for the treatment of grogginess
GB0312425D0 (en) * 2003-05-30 2003-07-09 Boots Co Plc Use of a compound in the treatment of sleep disorders and the like,in providing refreshedness on waking and a method for the treatment of grogginess therewith
DE10325140B4 (en) * 2003-06-04 2014-12-31 Lts Lohmann Therapie-Systeme Ag Direct coating method and apparatus
US8703209B2 (en) * 2003-06-17 2014-04-22 Edward Larry McCleary Composition and method for modulating hydrogen ion physiology
US20070059346A1 (en) * 2003-07-01 2007-03-15 Todd Maibach Film comprising therapeutic agents
US9675548B2 (en) * 2003-07-24 2017-06-13 GlaxoSmithKline, LLC Orally dissolving films
US20050069501A1 (en) * 2003-08-15 2005-03-31 Sayed Ibrahim Rapid temporary tooth whitening composition
US7666396B2 (en) * 2003-09-11 2010-02-23 Kimberly-Clark Worldwide, Inc. Single-use moisturizing product
US20050072443A1 (en) * 2003-10-06 2005-04-07 Kuchenbecker Lee Ann Dental hygiene accessories
US20050075432A1 (en) * 2003-10-07 2005-04-07 Verrall Andrew P. Acidulent film and method of making same
US20050079253A1 (en) * 2003-10-10 2005-04-14 Hiroshi Nakamura Bilayer edible sheet
US9248146B2 (en) * 2003-10-24 2016-02-02 Adhesives Research, Inc. Dissolvable adhesive films for delivery of pharmaceutical or cosmetic agents
DK1695094T3 (en) * 2003-10-24 2013-09-16 Adhesives Res Inc Disintegrating films for diagnostic devices
NO320283B1 (en) * 2003-10-30 2005-11-21 Ntnu Technology Transfer As Use of the plant Sphagnum, oral hygiene product and methods for controlling unwanted bacterial flora on teeth
US20050147651A1 (en) * 2003-11-03 2005-07-07 Hill's Pet Nutrition, Inc. Coated pet food composition
AU2004289248B2 (en) 2003-11-07 2012-05-03 U.S. Smokeless Tobacco Company Llc Tobacco compositions
US8627828B2 (en) 2003-11-07 2014-01-14 U.S. Smokeless Tobacco Company Llc Tobacco compositions
WO2005048931A2 (en) * 2003-11-13 2005-06-02 Dbc, Llc Dissolving thin film xanthone supplement
DE10354894A1 (en) * 2003-11-24 2005-07-07 Hf Arzneimittelforschung Gmbh Oral formulations of deoxypeganine and their applications
US7285520B2 (en) 2003-12-01 2007-10-23 Kimberly-Clark Worldwide, Inc. Water disintegratable cleansing wipes
PL1713544T3 (en) 2003-12-16 2009-12-31 Colgate Palmolive Co Oral and personal care compositions and methods
NZ548218A (en) 2003-12-19 2009-02-28 Univ Melbourne Antimicrobial composition comprising a casein peptide and a divalent cation useful for treating dental caries
US20050136112A1 (en) * 2003-12-19 2005-06-23 Pediamed Pharmaceuticals, Inc. Oral medicament delivery system
US20050137262A1 (en) * 2003-12-22 2005-06-23 Hu Patrick C. Highly concentrated pourable aqueous solutions of potassium ibuprofen, their preparation and their uses
DE102004002951A1 (en) * 2004-01-21 2005-08-11 Wella Ag Process for producing hair-setting products in film form
CA2554649C (en) * 2004-01-30 2015-10-27 Corium International, Inc. Rapidly dissolving film for delivery of an active agent
AR047658A1 (en) 2004-02-03 2006-02-01 Cargill Inc CONCENTRATE OF PROTEINS AND WATER CURRENT WITH HYDROSOLUBBLE CARBOHYDRATES
US20050186256A1 (en) * 2004-02-20 2005-08-25 Dihel Deborah L. Dissolvable film comprising an active ingredient and method of manufacture
US20050186257A1 (en) * 2004-02-20 2005-08-25 Todd Manegold Dissolvable film and method of manufacture
US20050196348A1 (en) * 2004-03-03 2005-09-08 Constantine Georgiades Stabilized peroxide compositions
US20080003248A1 (en) * 2004-03-03 2008-01-03 Constantine Georgiades Whitening products
US20050196354A1 (en) * 2004-03-03 2005-09-08 Andre Soshinsky Film compositions
US20050196497A1 (en) * 2004-03-03 2005-09-08 Kraft Foods Holdings, Inc. Antimicrobial effect of chitosan in beverages
US20050196355A1 (en) * 2004-03-03 2005-09-08 Constantine Georgiades Film products having controlled disintegration properties
WO2005092278A1 (en) * 2004-03-03 2005-10-06 Warner-Lambert Company Llc Stabilized peroxide compositions
US20070190125A1 (en) * 2004-03-03 2007-08-16 Constantine Georgiades Positioning feature for aiding use of film or strip product
US20070269519A1 (en) * 2004-03-03 2007-11-22 Constantine Georgiades Whitening products
US20050208108A1 (en) * 2004-03-19 2005-09-22 Jannusch Leonard C Thermoplastic films and methods for making
US20050226964A1 (en) * 2004-04-07 2005-10-13 Michael Small Water soluble seal and cap
US7850987B2 (en) * 2004-04-08 2010-12-14 Micronutrient, Llc Nutrient composition(s) and system(s) for individualized, responsive dosing regimens
US20050226906A1 (en) * 2004-04-08 2005-10-13 Micro Nutrient, Llc Nutrient system for individualized responsive dosing regimens
US7785619B2 (en) * 2004-04-08 2010-08-31 Micro Nutrient, Llc Pharmanutrient composition(s) and system(s) for individualized, responsive dosing regimens
US20050230871A1 (en) * 2004-04-20 2005-10-20 Bess William S Fast-dissolving films
EP1593376A1 (en) * 2004-05-04 2005-11-09 Warner-Lambert Company LLC Improved pullulan capsules
US7118732B2 (en) * 2004-05-10 2006-10-10 Colgate-Palmolive Company Tooth-whitening compositions comprising silicone polymer and methods therefor
CA2470463C (en) 2004-06-09 2012-09-18 Lornamead Brands, Inc. Tooth whitening products and methods of making the same
EP1758554A1 (en) * 2004-06-12 2007-03-07 Passion For Life Healthcare Limited Soluble strip for oral or topical adminstration
US7281541B2 (en) * 2004-06-16 2007-10-16 Lorch Leonard G Dental floss
US20050281757A1 (en) * 2004-06-17 2005-12-22 Sayed Ibrahim Oral care film
US9267167B2 (en) * 2004-06-28 2016-02-23 Becton, Dickinson And Company Dissolvable films and methods including the same
US7334538B1 (en) * 2004-07-27 2008-02-26 Aquascience Research Group, Inc. Topical medicants for aquatic animals
US20060024425A1 (en) 2004-07-30 2006-02-02 Wm. Wrigley Jr. Company Edible film compositions
DE602005021126D1 (en) 2004-08-02 2010-06-17 Glaxo Group Ltd NEW COMPOSITION AGAINST XEROSTOMY
JP5270158B2 (en) 2004-08-05 2013-08-21 コリウム インターナショナル， インコーポレイテッド Adhesive composition
US7959902B1 (en) * 2004-09-21 2011-06-14 Postlewaite Laura M Device and method for treating the oral cavity
US20060062811A1 (en) * 2004-09-21 2006-03-23 Szymczak Christopher E Medicinal cooling emulsions
DK1791791T3 (en) * 2004-09-27 2019-08-26 Special Water Patents B V Methods and compositions for treating water
CA2582326A1 (en) * 2004-09-30 2006-04-13 Homaro R. Cantu System and methods for preparing substitute food items
CN101146457B (en) * 2004-09-30 2012-03-28 好时公司 Sealed, edible film strip packets and methods of making and using them
US20060104910A1 (en) * 2004-11-15 2006-05-18 Keith Lerner Over dosage indicating medicated film strip
US8758816B2 (en) * 2004-11-24 2014-06-24 Meda Pharmaceuticals Inc. Compositions comprising azelastine and methods of use thereof
US20070020330A1 (en) * 2004-11-24 2007-01-25 Medpointe Healthcare Inc. Compositions comprising azelastine and methods of use thereof
DK2486942T3 (en) 2004-11-24 2019-01-28 Meda Pharmaceuticals Inc COMPOSITIONS CONTAINING AZELASTINE AND PROCEDURES FOR USING IT
KR100701409B1 (en) * 2004-11-26 2007-03-30 한국유나이티드제약 주식회사 Pharmaceutical formulations containing sumatriptan succinate
US20060159773A1 (en) * 2005-01-20 2006-07-20 Stephen Holt Herbal compositions containing hoodia
WO2006081618A1 (en) 2005-02-02 2006-08-10 Novapharm Research (Australia) Pty Ltd Biostatic polymeric formed articles
US20070275135A1 (en) * 2005-02-09 2007-11-29 First Flavor, Inc. Taste sampling process and product
DE602006020985D1 (en) * 2005-02-14 2011-05-12 Mcneil Ppc Inc PACKAGING FOR A BODY CARE PRODUCT
US20090076168A1 (en) * 2005-03-04 2009-03-19 Tien Canh Le Amine-based and imine-based polymers, uses and preparation thereof
US20060207721A1 (en) * 2005-03-17 2006-09-21 Greg Slominski Polymer adhesive splicing of water-soluble, orally ingestible thin film webs
WO2006107390A2 (en) 2005-04-04 2006-10-12 Kronos Advanced Technologies, Inc. An electrostatic fluid accelerator for and method of controlling a fluid flow
US8597709B2 (en) 2005-04-12 2013-12-03 Inovobiologic Inc. Dietary supplement and methods of use
US8062686B2 (en) 2005-04-12 2011-11-22 InovoBiologics, Inc. Dietary supplement, and methods of use
EP1877094A1 (en) * 2005-05-03 2008-01-16 Innozen, Inc. Edible film for transmucosal delivery of nutritional supplements
US20060254949A1 (en) * 2005-05-12 2006-11-16 Staggs William B Jr Credit card-shaped drug delivery system
EP1888025B1 (en) * 2005-06-08 2020-08-12 Basf Corporation Medicament carrier composition and method of forming a film therefrom
US8975227B2 (en) 2005-07-15 2015-03-10 Emisphere Technologies, Inc. Intraoral dosage forms of glucagon
AU2006279593B2 (en) * 2005-08-18 2011-06-02 Colgate-Palmolive Company Cleansing compositions containing film
US7861728B2 (en) * 2006-02-10 2011-01-04 R.J. Reynolds Tobacco Company Smokeless tobacco composition having an outer and inner pouch
EP1948236B1 (en) 2005-09-27 2021-03-03 Special Water Patents B.V. Methods and compositions for treatment of skin
US20070077300A1 (en) * 2005-09-30 2007-04-05 Wynn David W Oral compositions containing a salivation inducing agent
US20070098746A1 (en) 2005-11-02 2007-05-03 Nichols William M Multi-layered coating technology for taste masking
US7470442B2 (en) * 2005-12-02 2008-12-30 Gic Innovations Company Confectionary compositions with magnolia bark extract
US7544377B2 (en) * 2005-12-02 2009-06-09 Gic Innovations Company Chewable compositions with fast release magnolia bark extract
US7592025B2 (en) * 2005-12-02 2009-09-22 Gic Innovations Company Vehicles for oral care with magnolia bark extract
US20070134297A1 (en) * 2005-12-08 2007-06-14 Naqam Washington Device to aid in sexual pleasure
US20070137668A1 (en) * 2005-12-15 2007-06-21 Borschke August J Smoking articles and wrapping materials therefor
US20070140992A1 (en) * 2005-12-21 2007-06-21 Lynn Schick Taste masking of essential oils using a hydrocolloid
US20070148213A1 (en) 2005-12-22 2007-06-28 Sayed Ibrahim Film containing compositions
WO2007078874A2 (en) * 2005-12-30 2007-07-12 Cogentus Pharmaceuticals, Inc. Oral pharmaceutical formulations containing non-steroidal anti-inflammatory drugs and acid inhibitors
WO2007084587A2 (en) * 2006-01-20 2007-07-26 Monosol Rx, Llc Film lined pouch and method of manufacturing this pouch
US7810507B2 (en) * 2006-02-10 2010-10-12 R. J. Reynolds Tobacco Company Smokeless tobacco composition
CN101384249B (en) * 2006-02-17 2011-11-30 诺瓦提斯公司 Disintegrable oral films
US9668476B2 (en) * 2006-02-23 2017-06-06 Lanxess Corporation Removable antimicrobial coating compositions and methods of use
JP5242543B2 (en) * 2006-03-16 2013-07-24 ノバルティス アーゲー Solid dosage form containing a taste masked active agent
US20070218090A1 (en) * 2006-03-17 2007-09-20 Craig Berry Dissolvable strip for delivery of an agent
EP2007362B1 (en) 2006-04-04 2018-09-05 KG Acquisition LLC Oral dosage forms including an antiplatelet agent and an acid inhibitor
US20070231387A1 (en) * 2006-04-04 2007-10-04 Luigi Levi Film-coated solid dosage forms
US20070235350A1 (en) * 2006-04-06 2007-10-11 John Warlick Wallet Sized Medicament Dispenser
US20070235349A1 (en) * 2006-04-06 2007-10-11 General Patent, Llc Medicament Dispenser
WO2007127810A2 (en) * 2006-04-25 2007-11-08 Kronos Advanced Technologies, Inc. Electrostatic loudspeaker and method of acoustic waves generation
IL175338A0 (en) * 2006-05-01 2006-09-05 Biota Ltd Orally administrable films and preparation thereof
US8187659B2 (en) * 2006-05-02 2012-05-29 Jerry Robertson Real Estate Llc Solid medicament dosage form consumption aid
US7946296B2 (en) 2006-05-26 2011-05-24 Philip Morris Usa Inc. Dissolvable tobacco film strips and method of making the same
TW200815048A (en) * 2006-06-05 2008-04-01 Verus Pharmaceuticals Inc Methods for buccal, lingual or sublingual dosing regimens of epinephrine for the treatment of allergic emergencies
TW200817049A (en) * 2006-06-05 2008-04-16 Verus Pharmaceuticals Inc Epinephrine dosing regimens comprising buccal, lingual or sublingual and injectable dosage forms
JP4859115B2 (en) * 2006-06-07 2012-01-25 松谷化学工業株式会社 Edible film for oral hygiene
US20080152761A1 (en) * 2006-12-20 2008-06-26 Shiji Shen Packaging of Food Products with Pullulan Films
US20070292481A1 (en) * 2006-06-16 2007-12-20 Hoffman Andrew J Packaging of Food Products with Pullulan Films
US20070298078A1 (en) * 2006-06-27 2007-12-27 Harrison Michael D Water Soluble Article for Imparting Dietary Fiber to Bottled Water
WO2008008120A1 (en) * 2006-07-14 2008-01-17 Fmc Corporation Solid form
JP2009541301A (en) * 2006-07-14 2009-11-26 ザ プロクター アンド ギャンブル カンパニー Treatment article capable of delivering intensive care and overall treatment simultaneously
US20080026062A1 (en) * 2006-07-31 2008-01-31 Isaac Farr Pharmaceutical compositions including nano-sized active agent
US20080026040A1 (en) * 2006-07-31 2008-01-31 Isaac Farr Active agent-releasing dosage forms
CA2656397A1 (en) * 2006-09-05 2008-03-13 University Of Manitoba Antimicrobial coatings
JP5014712B2 (en) * 2006-09-06 2012-08-29 ライオン株式会社 Oral dissolution film
CN101516331A (en) * 2006-09-20 2009-08-26 莫诺索尔克斯有限公司 Edible water-soluble film containing a foam reducing flavoring agent
CN101534799A (en) * 2006-09-29 2009-09-16 莫诺索尔克斯有限公司 Film embedded packaging and method of making same
MX2009003372A (en) * 2006-10-02 2009-09-24 Labtec Gmbh Non-mucoadhesive film dosage forms.
US20100172956A1 (en) * 2006-10-13 2010-07-08 Thomas Kalili Dissolving strip for oral mucosa as a systemic drug delivery route
DE102006061287A1 (en) * 2006-12-22 2008-06-26 Lts Lohmann Therapie-Systeme Ag Edible foil-shaped preparation with cola flavor
WO2008080146A1 (en) * 2006-12-26 2008-07-03 Discus Dental, Llc Disposable tongue scraper
US20100215774A1 (en) * 2007-02-09 2010-08-26 Todd Maibach Film comprising nitroglycerin
MX2009006114A (en) * 2007-03-02 2009-11-10 Meda Pharmaceuticals Inc Compositions comprising carisoprodol and methods of use thereof.
US20080220029A1 (en) * 2007-03-05 2008-09-11 Charlene Ng Fast-dissolving/disintegrating film preparation having high proportion of active
US8663659B2 (en) * 2007-03-07 2014-03-04 Novartis Ag Orally administrable films
US20090011115A1 (en) * 2007-03-13 2009-01-08 Foss Carter D Edible Pullulan Films Containing Flavoring
US8568777B2 (en) * 2007-03-30 2013-10-29 Monosol Rx, Llc Packaged film dosage unit containing a complexate
CA2682752C (en) 2007-04-05 2015-07-07 University Of Kansas Rapidly dissolving pharmaceutical compositions comprising pullulan
US8900629B2 (en) 2007-04-05 2014-12-02 University Of Kansas Rapidly dissolving pharmaceutical compositions comprising pullulan
WO2008127902A2 (en) * 2007-04-12 2008-10-23 Tate & Lyle Ingredients Americas, Inc. Pullulan film containing sweetener
US20080260836A1 (en) * 2007-04-18 2008-10-23 Thomas James Boyd Films Comprising a Plurality of Polymers
US20080274187A1 (en) * 2007-05-02 2008-11-06 J.C. Bright M. Ltd. Hard capsule composition and method of use
WO2008137164A1 (en) * 2007-05-07 2008-11-13 Hwa-Song Liu Edible thin film strips and process for making
US20080311162A1 (en) * 2007-05-16 2008-12-18 Olivia Darmuzey Solid form
EP2161021B1 (en) * 2007-06-07 2017-03-08 Sato Pharmaceutical Co. Ltd. Medicinal film preparation with rapidly dissolving property and flexibility
CN101073407B (en) * 2007-06-15 2011-04-20 广东富味制果厂有限公司 Edible refreshing pearl and its production
US20090004254A1 (en) * 2007-06-19 2009-01-01 Todd Maibach Film comprising active drugs
WO2008157033A1 (en) 2007-06-20 2008-12-24 Mcneil-Ppc, Inc Products for whitening teeth
JP5101191B2 (en) * 2007-06-29 2012-12-19 リンテック株式会社 Film-form preparation and method for producing the same
US20090010998A1 (en) * 2007-07-03 2009-01-08 Marchitto Kevin S Drug-delivery patch comprising a dissolvable layer and uses thereof
EP2179666B1 (en) 2007-07-23 2012-08-29 R.J.Reynolds Tobacco Company Smokeless Tobacco Compositions And Methods For Treating Tobacco For Use Therein
JP5628031B2 (en) * 2007-07-25 2014-11-19 スリーエム イノベイティブ プロパティズ カンパニー Therapeutic dental composition and related methods
US20090036413A1 (en) * 2007-07-31 2009-02-05 Bill Mcanalley Compositions, uses, and method of making wound care products from naturally occurring food ingredients
KR100937625B1 (en) * 2007-08-10 2010-01-20 주식회사 제닉 Dissolvable Web Porous Film and Preparing Method Thereof
US8323695B2 (en) 2007-08-13 2012-12-04 Mcneil-Ppc, Inc. Method for stabilizing phenylephrine
JP2009096803A (en) * 2007-09-26 2009-05-07 Showa Kako Kk Oral cavity patch type slowly soluble preparation
WO2009043588A2 (en) * 2007-10-02 2009-04-09 LABTEC Gesellschaft für technologische Forschung und Entwicklung mbH Ph regulating antibacterial films for the oral or vaginal cavity
KR100905027B1 (en) * 2007-10-03 2009-06-30 (주)씨엘팜 Edible Film
EA021392B1 (en) 2007-10-11 2015-06-30 Филип Моррис Продактс С.А. Smokeless tobacco product
US9125434B2 (en) * 2007-10-11 2015-09-08 Philip Morris Products S.A. Smokeless tobacco product, smokeless tobacco product in the form of a sheet, extrudable tobacco composition, method for manufacturing a smokeless tobacco product, method for delivering super bioavailable nicotine contained in tobacco to a user, and packaged smokeless tobacco product sheet
US20090098192A1 (en) * 2007-10-11 2009-04-16 Fuisz Richard C Extrudable and Extruded Compositions for Delivery of Bioactive Agents, Method of Making Same and Method of Using Same
US20090142452A1 (en) * 2007-11-19 2009-06-04 Michael David Campbell Dissolvable Orally Consumable Flavored Sensual Enhancement Films
WO2009073190A1 (en) * 2007-12-04 2009-06-11 Swedish Match North America, Inc. Fast dissolving films and coatings for controlled release of flavors, active pharmaceutical ingredients, food substances, and nicotine
US20090162516A1 (en) * 2007-12-21 2009-06-25 Brown Solomon E Edible, water-soluble film
MX2010006972A (en) 2007-12-21 2010-08-26 Ligand Pharm Inc Selective androgen receptor modulators (sarms) and uses thereof.
US8771643B2 (en) 2008-01-04 2014-07-08 Schabar Research Associates Llc Use of analgesic potentiating compounds to potentiate the analgesic properties of an analgesic compound
EP2234606A2 (en) * 2008-01-31 2010-10-06 McNeil-PPC, Inc. Edible film-strips with modified release active ingredients
EP2244699A2 (en) * 2008-01-31 2010-11-03 Mcneil-PPC, Inc Edible film-strips for immediate release of active ingredients
US8497409B2 (en) 2008-02-29 2013-07-30 Kimberly-Clark Worldwide, Inc. Absorbent article having an olfactory wetness signal
CA2726259C (en) 2008-06-04 2014-07-29 Colgate-Palmolive Company Oral care implement with cavitation system
GB2460915B (en) 2008-06-16 2011-05-25 Biovascular Inc Controlled release compositions of agents that reduce circulating levels of platelets and methods therefor
TWI513478B (en) * 2008-08-25 2015-12-21 Kyukyu Yakuhin Kogyo Kk Lopamine hydrochloride (LOPERAMIDE) hydrochloride film preparation
US8715715B2 (en) 2008-11-03 2014-05-06 Nal Pharmaceuticals Ltd. Dosage form for insertion into the mouth
CA2749564C (en) * 2009-01-13 2016-11-15 Monosolrx Llc Unit assembly for multiple film dosages, apparatus, and methods
WO2010083035A2 (en) 2009-01-14 2010-07-22 Corium International, Inc. Transdermal administration of tamsulosin
WO2010083360A2 (en) 2009-01-16 2010-07-22 Mutual Pharmaceutical Company, Inc. Controlled-release formulations
US20100209484A1 (en) * 2009-02-13 2010-08-19 Hoo-Kyun Choi Transdermal Triptan Delivery System
CA2755543A1 (en) * 2009-03-13 2010-09-16 Nucitec S.A. De C.V. Compositions and methods for treatment and prevention of cardiovascular disease
EP2233134A1 (en) 2009-03-27 2010-09-29 McNeil AB Multi-portion intra-oral dosage form with organoleptic properties
US20100256197A1 (en) * 2009-04-02 2010-10-07 Silver Eagle Labs Nv, Llc Nicotine Dissolving Film With Or Without Menthol
US20100256215A1 (en) * 2009-04-02 2010-10-07 Silver Eagle Labs Nv, Llc Menthol-Melatonin Dissolving Film
JP2010254603A (en) * 2009-04-23 2010-11-11 Osaka Univ Oral cavity composition
TWI442937B (en) * 2009-05-26 2014-07-01 Colgate Palmolive Co Higher loading zinc-containing films
CA2760227C (en) 2009-05-26 2015-05-05 Colgate-Palmolive Company Dentifrice composition
TWI396554B (en) 2009-05-26 2013-05-21 Colgate Palmolive Co Oral care formulations that enhance amount of soluble zinc
WO2010150930A1 (en) * 2009-06-25 2010-12-29 (주)벡스코아 Fast dissolving film for oral administration which prevents unpleasant taste effectively
US20110177146A1 (en) * 2009-07-27 2011-07-21 E. I. Du Pont De Nemours And Company Removable antimicrobial coating compositions containing cationic rheology agent and methods of use
CN102470078A (en) * 2009-07-30 2012-05-23 宝洁公司 Oral care articles and methods
US20110027199A1 (en) * 2009-07-30 2011-02-03 Danny Frye Drink container with a breath strip
US8475832B2 (en) 2009-08-07 2013-07-02 Rb Pharmaceuticals Limited Sublingual and buccal film compositions
TR200907338A1 (en) * 2009-09-28 2011-04-21 Yedi̇tepe Üni̇versi̇tesi̇ A film strip containing natural ingredients.
KR20140088236A (en) 2009-10-01 2014-07-09 앱탈리스 파마테크, 인코포레이티드 Orally administered corticosteroid compositions
US8357398B2 (en) * 2009-10-21 2013-01-22 Alitair Pharmaceuticals Inc. Benzonatate compositions and methods of use
WO2014057351A1 (en) * 2012-10-11 2014-04-17 Ix Biopharma Ltd Solid dosage form
US9549842B2 (en) 2011-02-04 2017-01-24 Joseph E. Kovarik Buccal bioadhesive strip and method of treating snoring and sleep apnea
US8701671B2 (en) 2011-02-04 2014-04-22 Joseph E. Kovarik Non-surgical method and system for reducing snoring
CA2780264C (en) 2009-12-04 2016-02-02 Colgate-Palmolive Company Dissolvable films containing high concentrations of nonionic surfactants such as polysorbates to enhance high solid loadings
US10610528B2 (en) 2009-12-08 2020-04-07 Intelgenx Corp. Solid oral film dosage forms and methods for making same
US20110136815A1 (en) 2009-12-08 2011-06-09 Horst Zerbe Solid oral film dosage forms and methods for making same
WO2011081625A1 (en) 2009-12-30 2011-07-07 Novartis Ag Melt extruded thin strips containing coated pharmaceutical actives
ES2539660T3 (en) 2009-12-30 2015-07-02 Novartis Ag Thin extruded nicotine strips
TWI458497B (en) 2010-01-13 2014-11-01 Colgate Palmolive Co Stabilization of zinc oxide film in oral compositions
TWI435733B (en) 2010-01-29 2014-05-01 Colgate Palmolive Co Oral care formulations for malodor control
US8397945B2 (en) 2010-02-23 2013-03-19 R.J. Reynolds Tobacco Company Dispensing container
KR20130029758A (en) * 2010-03-03 2013-03-25 코와 가부시키가이샤 Film preparation containing medicament with unpleasant taste
DE102010014869A1 (en) * 2010-04-13 2011-10-13 Lts Lohmann Therapie-Systeme Ag Hydrogel for natural cosmetic purposes
US20110268809A1 (en) 2010-04-28 2011-11-03 Paul Andrew Brinkley Nicotine-Containing Pharmaceutical Compositions
US20110274628A1 (en) 2010-05-07 2011-11-10 Borschke August J Nicotine-containing pharmaceutical compositions
US8232238B2 (en) 2010-06-03 2012-07-31 The Clorox Company Concentrated film delivery systems
EP2579844B1 (en) 2010-06-10 2016-02-24 Midatech Ltd. Nanoparticle film delivery systems
CN103140207A (en) 2010-06-23 2013-06-05 高露洁-棕榄公司 Encapsulation of ingredients in lactose matrix to form active encapsulates
RU2013103829A (en) 2010-06-30 2014-08-10 Колгейт-Палмолив Компани MULTI-LAYERED FILMS FOR DELIVERY OF TASTE-AROMATIC ADDITIVES
SG185629A1 (en) 2010-06-30 2012-12-28 Colgate Palmolive Co Flavor release from multilayer film during brushing
EP2588655B1 (en) 2010-07-02 2017-11-15 The Procter and Gamble Company Method for delivering an active agent
MX2013000201A (en) 2010-07-02 2013-08-21 Procter & Gamble Methods of delivering a health care active by administering personal health care articles comprising a filament.
WO2012003316A1 (en) 2010-07-02 2012-01-05 The Procter & Gamble Company Process for making films from nonwoven webs
RU2541949C2 (en) 2010-07-02 2015-02-20 Дзе Проктер Энд Гэмбл Компани Filaments, containing active agent, non-woven cloths and methods of obtaining them
EP2588589B2 (en) 2010-07-02 2023-07-19 The Procter & Gamble Company Process for the production of a detergent product
WO2012003365A1 (en) 2010-07-02 2012-01-05 The Procter & Gamble Company Filaments comprising an ingestible active agent nonwoven webs and methods for making same
US10028520B2 (en) 2010-09-02 2018-07-24 R.J. Reynolds Tobacco Company Apparatus for manufacturing a smokeless tobacco product incorporating an object, and associated method
DE102010048408A1 (en) 2010-10-15 2012-04-19 Lts Lohmann Therapie-Systeme Ag Laminate with improved water retention behavior
US9149959B2 (en) 2010-10-22 2015-10-06 Monosol Rx, Llc Manufacturing of small film strips
US10238684B2 (en) 2010-11-18 2019-03-26 Foundational Biosystems, Llc Micro- and nano-quantity sleep enhancing nutrient composition and method of enhancing central nervous system protein clearance using same
US9648874B2 (en) * 2010-12-07 2017-05-16 Kimberly-Clark Worldwide, Inc. Natural, multiple use and re-use, user saturated wipes
CA2817046C (en) 2010-12-07 2016-08-16 Colgate-Palmolive Company Oral and personal care compositions comprising zinc containing films
JP2014501258A (en) 2010-12-23 2014-01-20 コルゲート・パーモリブ・カンパニー Fluid composition comprising a structuring agent
CA2821921A1 (en) 2010-12-23 2012-06-28 Colgate-Palmolive Company Aqueous oral care composition comprising xanthan gum, cellulose gum and carbomer
EP2663294B1 (en) 2011-01-11 2015-09-30 Capsugel Belgium NV New hard capsules comprising pullulan
US9277977B2 (en) 2011-01-24 2016-03-08 Leonard G. Lorch Dental floss
US9277976B2 (en) 2011-01-24 2016-03-08 Leonard G. Lorch Dental floss
US8381742B2 (en) 2011-01-24 2013-02-26 Leonard G. Lorch Dental floss
US10206765B2 (en) 2011-01-24 2019-02-19 Leonard G. Lorch Dental floss
US10085938B2 (en) 2011-02-04 2018-10-02 Joseph E. Kovarik Method and system for preventing sore throat in humans
US11844720B2 (en) 2011-02-04 2023-12-19 Seed Health, Inc. Method and system to reduce the likelihood of dental caries and halitosis
US11357722B2 (en) 2011-02-04 2022-06-14 Seed Health, Inc. Method and system for preventing sore throat in humans
EP2701534A1 (en) 2011-04-28 2014-03-05 ACME Specialty Products, LLC Taste masking compositions and edible forms thereof
KR101303479B1 (en) * 2011-07-28 2013-09-06 (주)씨엘팜 Composition for edible film and pharmaceutical preparation for edible film containing drugs
JP5781037B2 (en) * 2011-09-15 2015-09-16 ローム アンド ハース カンパニーＲｏｈｍ Ａｎｄ Ｈａａｓ Ｃｏｍｐａｎｙ Low gloss aqueous coating composition comprising poly (ethylene oxide)
JP5496287B2 (en) * 2011-09-15 2014-05-21 ローム アンド ハース カンパニー Low gloss aqueous coating composition containing poly (ethylene oxide) for use in leather
US9084439B2 (en) 2011-09-22 2015-07-21 R.J. Reynolds Tobacco Company Translucent smokeless tobacco product
US20130078307A1 (en) 2011-09-22 2013-03-28 Niconovum Usa, Inc. Nicotine-containing pharmaceutical composition
US9474303B2 (en) 2011-09-22 2016-10-25 R.J. Reynolds Tobacco Company Translucent smokeless tobacco product
US9629392B2 (en) 2011-09-22 2017-04-25 R.J. Reynolds Tobacco Company Translucent smokeless tobacco product
AU2012315782B2 (en) 2011-09-30 2015-10-29 Perio Sciences, Llc Antioxidant compositions for treatment of inflammation or oxidative damage
US9907748B2 (en) 2011-10-21 2018-03-06 Niconovum Usa, Inc. Excipients for nicotine-containing therapeutic compositions
CA2855732C (en) 2011-12-15 2016-06-28 Colgate-Palmolive Company Aqueous oral care compositions
US8574628B2 (en) * 2011-12-19 2013-11-05 Kimberly-Clark Worldwide, Inc. Natural, multiple release and re-use compositions
US9763928B2 (en) 2012-02-10 2017-09-19 Niconovum Usa, Inc. Multi-layer nicotine-containing pharmaceutical composition
US9420825B2 (en) 2012-02-13 2016-08-23 R.J. Reynolds Tobacco Company Whitened tobacco composition
JP6050031B2 (en) * 2012-06-01 2016-12-21 森下仁丹株式会社 Film formulation
WO2014000803A1 (en) * 2012-06-28 2014-01-03 Optimags Dr. Zimmermann Gmbh Method for producing a film formulation for an edible film, and the use thereof
WO2014018075A1 (en) 2012-07-23 2014-01-30 Crayola, Llc Dissolvable films and methods of using the same
CN102836144A (en) * 2012-09-28 2012-12-26 天津市聚星康华医药科技有限公司 Deoxidized epinephrine oral instant film and preparation method thereof
DE202013000446U1 (en) * 2012-10-04 2013-10-07 Maria Clementine Martin Klosterfrau Vertriebsgesellschaft Mbh Composition, in particular pharmaceutical composition, in particular for administration in hoarseness and sore throat
CN102871984B (en) * 2012-11-05 2015-11-11 天津市聚星康华医药科技有限公司 A kind of Phenylephrine hydrochloride oral instant membrane and preparation method thereof
US8859005B2 (en) 2012-12-03 2014-10-14 Intercontinental Great Brands Llc Enteric delivery of functional ingredients suitable for hot comestible applications
WO2014105783A1 (en) * 2012-12-28 2014-07-03 Noven Pharmaceuticals, Inc. Compositions and methods for transdermal delivery of amphetamine and clonidine
WO2014116770A1 (en) 2013-01-23 2014-07-31 Arx, Llc Production of unit dose constructs
EP2950775B1 (en) * 2013-01-31 2018-08-01 The Procter and Gamble Company Cleansing composition and a wet wipe comprising the same
US20140255452A1 (en) 2013-03-11 2014-09-11 Niconovum Usa, Inc. Method and apparatus for differentiating oral pouch products
WO2014159673A2 (en) 2013-03-14 2014-10-02 Altria Client Services Inc. Soft oral product
WO2014145699A1 (en) 2013-03-15 2014-09-18 New Jersey Institute Of Technology System and method for fabrication of uniform polymer films containing nano and micro particles via continuous drying process
US9278050B2 (en) 2013-04-01 2016-03-08 Trevor Anderson Dissolvable medication administration bag and method of using the same
PH12014000076A1 (en) 2013-07-01 2015-09-07 Priscila F Kimes Improved processes in the preparation of coconut meat based composition and films
TW201503831A (en) * 2013-07-11 2015-02-01 Agrofresh Inc Humidity activated formulation for volatile compounds
TW201536214A (en) * 2013-07-16 2015-10-01 Colgate Palmolive Co System and method for making an oral care formulation
WO2015034678A2 (en) 2013-09-06 2015-03-12 Aptalis Pharmatech, Inc. Corticosteroid containing orally disintegrating tablet compositions for eosinophilic esophagitis
US11503853B2 (en) 2013-09-09 2022-11-22 R.J. Reynolds Tobacco Company Smokeless tobacco composition incorporating a botanical material
US10357054B2 (en) 2013-10-16 2019-07-23 R.J. Reynolds Tobacco Company Smokeless tobacco pastille
WO2015068058A1 (en) 2013-11-06 2015-05-14 Rk Technology & Investments Pte. Ltd. Tobacco free 'niconuts'and the process thereof
WO2015066819A1 (en) 2013-11-08 2015-05-14 Carlos Filipe Method of stabilizing molecules without refrigeration using water soluble polymers and applications thereof in performing chemical reactions
US9668970B2 (en) 2013-12-02 2017-06-06 Intelgenx Corp. Film dosage form with extended release mucoadhesive particles
US10272038B2 (en) 2013-12-02 2019-04-30 Intelgenx Corp. Film dosage form with extended release mucoadhesive particles
US11033493B2 (en) 2013-12-02 2021-06-15 Intelgenx Corp. Film dosage form with extended release mucoadhesive particles
US11826388B2 (en) 2013-12-20 2023-11-28 Seed Health, Inc. Topical application of Lactobacillus crispatus to ameliorate barrier damage and inflammation
US11839632B2 (en) 2013-12-20 2023-12-12 Seed Health, Inc. Topical application of CRISPR-modified bacteria to treat acne vulgaris
US11833177B2 (en) 2013-12-20 2023-12-05 Seed Health, Inc. Probiotic to enhance an individual's skin microbiome
EP3094323A4 (en) 2014-01-17 2017-10-11 Ligand Pharmaceuticals Incorporated Methods and compositions for modulating hormone levels
US9392814B2 (en) 2014-06-06 2016-07-19 Nicholas J. Singer Delivery system for drinks
US20160044955A1 (en) * 2014-08-13 2016-02-18 R.J. Reynolds Tobacco Company Smokeless tobacco products
US10959456B2 (en) 2014-09-12 2021-03-30 R.J. Reynolds Tobacco Company Nonwoven pouch comprising heat sealable binder fiber
FR3029103B1 (en) 2014-11-27 2018-02-16 Societe Industrielle Limousine D'application Biologique SOLUBLE ADHESIVE DRESSING BASED ON MINERALS
US20160157515A1 (en) 2014-12-05 2016-06-09 R.J. Reynolds Tobacco Company Smokeless tobacco pouch
CA2969466A1 (en) 2014-12-09 2016-06-16 Monosolrx Llc Linear polysaccharide based film products
US9956323B2 (en) 2014-12-18 2018-05-01 Cook Medical Technologies Llc Medical devices for local bioactive delivery
EP3061501A1 (en) 2015-02-27 2016-08-31 Rottapharm Ltd. Composition for the treatment of acne
US20160339086A1 (en) * 2015-05-19 2016-11-24 Suzy Cohen Compositions and methods for treating thyroid disease
USD773313S1 (en) 2015-06-23 2016-12-06 Nicholas J. Singer Package
EP3117825A1 (en) 2015-07-16 2017-01-18 Rottapharm S.p.A. Oral formulation comprising berberine and morus alba extract
US10342646B2 (en) * 2015-10-17 2019-07-09 James D. Welch Method of, and system for smoothing teeth
US11103732B1 (en) * 2015-10-17 2021-08-31 James D. Welch Method of improving the condition of teeth
US10532046B2 (en) 2015-12-03 2020-01-14 Niconovum Usa, Inc. Multi-phase delivery compositions and products incorporating such compositions
US20170165252A1 (en) 2015-12-10 2017-06-15 Niconovum Usa Inc. Protein-enriched therapeutic composition
US10499684B2 (en) 2016-01-28 2019-12-10 R.J. Reynolds Tobacco Company Tobacco-derived flavorants
US11154087B2 (en) 2016-02-02 2021-10-26 R.J. Reynolds Tobacco Company Method for preparing flavorful compounds isolated from black liquor and products incorporating the flavorful compounds
US10702590B2 (en) 2016-04-12 2020-07-07 Script Essentials, Llc Compositions and methods for treating thyroid disease
EP3766488A1 (en) 2016-04-12 2021-01-20 Schaneville, Scott Ingestible films having substances from hemp or cannabis
KR20230137362A (en) 2016-05-05 2023-10-04 어퀘스티브 테라퓨틱스, 아이엔씨. Enhanced delivery epinephrine compositions
US11273131B2 (en) 2016-05-05 2022-03-15 Aquestive Therapeutics, Inc. Pharmaceutical compositions with enhanced permeation
JP2018000402A (en) * 2016-06-30 2018-01-11 静岡県 Tongue cover
CN109562075A (en) * 2016-07-05 2019-04-02 葛兰素史克消费保健（美国）控股有限责任公司 Peroral dosage form comprising quick release outer coatings
WO2018022516A1 (en) * 2016-07-25 2018-02-01 Olyxir, Llc Olive leaf powder (olp) strips
TWI728172B (en) 2016-08-18 2021-05-21 美商愛戴爾製藥股份有限公司 Methods of treating eosinophilic esophagitis
US11007144B2 (en) 2016-11-15 2021-05-18 Klaria Pharma Holding Ab Pharmaceutical formulation
US9700518B1 (en) 2016-11-21 2017-07-11 Karl Wei Cao Dip molding process for the manufacture of hard capsule shells
US9579292B1 (en) 2016-11-21 2017-02-28 Karl Wei Cao Film forming hard capsule solution
CN110049803B (en) * 2017-01-09 2022-06-07 宝洁公司 Barrier patch with dissolvable film and method of improving the appearance of skin
JP6893650B2 (en) * 2017-02-24 2021-06-23 学校法人福岡大学 Release-controlled film containing water-soluble polysaccharides as the main component
US11091446B2 (en) 2017-03-24 2021-08-17 R.J. Reynolds Tobacco Company Methods of selectively forming substituted pyrazines
US10470487B2 (en) 2017-04-06 2019-11-12 R.J. Reynolds Tobacco Company Smoke treatment
BR112019021396A2 (en) 2017-04-14 2020-04-28 Capsugel Belgium Nv pullulan manufacturing process
US11576870B2 (en) 2017-04-14 2023-02-14 Capsugel Belgium Nv Pullulan capsules
DE102017112527B4 (en) 2017-06-07 2019-01-03 Lts Lohmann Therapie-Systeme Ag Fast disintegrating foam wafers with a high basis weight
GB201709141D0 (en) 2017-06-08 2017-07-26 Klaria Pharma Holding Ab Pharmaceutical formulation
DK3678648T3 (en) 2017-09-08 2023-09-11 Insignis Therapeutics Inc METHODS OF USING DIPIVEFRIN
US11779446B2 (en) 2017-11-21 2023-10-10 3M Innovative Properties Company Oral compositions and methods of use
DE102017127434A1 (en) 2017-11-21 2019-05-23 Lts Lohmann Therapie-Systeme Ag Pocket-shaped oral-release films with high drug loading
EP3727336A1 (en) 2017-12-20 2020-10-28 3M Innovative Properties Company Oral compositions and methods of use
US11324681B2 (en) 2017-12-20 2022-05-10 3M Innovative Properties Company Oral compositions and methods of use
WO2019147523A1 (en) 2018-01-26 2019-08-01 The Procter & Gamble Company Water-soluble articles and related processes
US11053466B2 (en) 2018-01-26 2021-07-06 The Procter & Gamble Company Water-soluble unit dose articles comprising perfume
US11193097B2 (en) 2018-01-26 2021-12-07 The Procter & Gamble Company Water-soluble unit dose articles comprising enzyme
CA3087583C (en) 2018-01-26 2024-01-09 The Procter & Gamble Company Water-soluble unit dose articles comprising perfume
WO2019168829A1 (en) 2018-02-27 2019-09-06 The Procter & Gamble Company A consumer product comprising a flat package containing unit dose articles
CN112384504A (en) 2018-06-15 2021-02-19 R.J.雷诺兹烟草公司 Purification of nicotine
GB2575625A (en) 2018-06-22 2020-01-22 Church & Dwight Co Inc Oral care compositions comprising benzocaine and mucoadhesive thin films formed therefrom
WO2020010173A1 (en) * 2018-07-06 2020-01-09 Kansas State University Research Foundation Lipid nanoemulsion-doped antimicrobial packaging films
US10982176B2 (en) 2018-07-27 2021-04-20 The Procter & Gamble Company Process of laundering fabrics using a water-soluble unit dose article
US20200196658A1 (en) 2018-12-20 2020-06-25 R.J. Reynolds Tobacco Company Method for whitening tobacco
DE102019100483A1 (en) 2019-01-10 2020-07-16 Lts Lohmann Therapie-Systeme Ag Oral thin film
EP3918045A1 (en) 2019-01-28 2021-12-08 The Procter & Gamble Company Recycleable, renewable, or biodegradable package
EP3930685A1 (en) 2019-03-01 2022-01-05 Insignis Therapeutics, Inc. Dipivefrin orally disintegrating tablet formulations
EP3712237A1 (en) 2019-03-19 2020-09-23 The Procter & Gamble Company Fibrous water-soluble unit dose articles comprising water-soluble fibrous structures
KR20200117411A (en) * 2019-04-04 2020-10-14 (주)지웰바이오 Antibacterial Composition for Inhibiting Oral Bacteria and orally disintegrating film
US11213062B2 (en) 2019-05-09 2022-01-04 American Snuff Company Stabilizer for moist snuff
CA3134222C (en) 2019-06-28 2024-01-16 The Procter & Gamble Company Dissolvable solid fibrous articles containing anionic surfactants
JP2022542838A (en) * 2019-08-14 2022-10-07 インターコンチネンタル グレート ブランズ エルエルシー Confectionery chip product and method of making same
US20210068448A1 (en) 2019-09-11 2021-03-11 Nicoventures Trading Limited Method for whitening tobacco
US20210068447A1 (en) 2019-09-11 2021-03-11 R. J. Reynolds Tobacco Company Pouched products with enhanced flavor stability
US20210068446A1 (en) 2019-09-11 2021-03-11 R. J. Reynolds Tobacco Company Oral product with cellulosic flavor stabilizer
CA3150662A1 (en) 2019-09-11 2021-03-18 Michael Andrew Zawadzki Alternative methods for whitening tobacco
US11369131B2 (en) 2019-09-13 2022-06-28 Nicoventures Trading Limited Method for whitening tobacco
JP2023506123A (en) 2019-10-31 2023-02-15 ニコベンチャーズ トレーディング リミテッド Oral product and manufacturing method
WO2021116856A2 (en) 2019-12-09 2021-06-17 Nicoventures Trading Limited Oral products
US11617744B2 (en) 2019-12-09 2023-04-04 Nico Ventures Trading Limited Moist oral compositions
WO2021116916A1 (en) 2019-12-09 2021-06-17 Nicoventures Trading Limited Oral product with multiple flavors having different release profiles
US11883527B2 (en) * 2019-12-09 2024-01-30 Nicoventures Trading Limited Oral composition and method of manufacture
WO2021116824A1 (en) 2019-12-09 2021-06-17 Nicoventures Trading Limited Oral product comprising a cannabinoid
WO2021116881A1 (en) 2019-12-09 2021-06-17 Nicoventures Trading Limited Oral product in a pourous pouch comprising a fleece material
WO2021116826A1 (en) 2019-12-09 2021-06-17 Nicoventures Trading Limited Oral product comprising a cannabinoid
WO2021116895A2 (en) 2019-12-09 2021-06-17 Nicoventures Trading Limited Stimulus-responsive pouch
US20210169138A1 (en) 2019-12-09 2021-06-10 Nicoventures Trading Limited Fibrous fleece material
WO2021116823A1 (en) 2019-12-09 2021-06-17 Nicoventures Trading Limited Oral product
US20210169123A1 (en) 2019-12-09 2021-06-10 Nicoventures Trading Limited Pouched products with enhanced flavor stability
BR112022010899A2 (en) 2019-12-09 2022-09-06 Nicoventures Trading Ltd ORAL PRODUCT WITH DISSOLUBLE COMPONENT
WO2021116842A1 (en) 2019-12-09 2021-06-17 Nicoventures Trading Limited Oral products with controlled release
US20210169784A1 (en) 2019-12-09 2021-06-10 Nicoventures Trading Limited Buffered oral compositions
WO2021116825A1 (en) 2019-12-09 2021-06-17 Nicoventures Trading Limited Oral product
US20210169785A1 (en) 2019-12-09 2021-06-10 Nicoventures Trading Limited Oral compositions with reduced water activity
US11872231B2 (en) 2019-12-09 2024-01-16 Nicoventures Trading Limited Moist oral product comprising an active ingredient
US11793230B2 (en) 2019-12-09 2023-10-24 Nicoventures Trading Limited Oral products with improved binding of active ingredients
US11672862B2 (en) 2019-12-09 2023-06-13 Nicoventures Trading Limited Oral products with reduced irritation
US20210169783A1 (en) 2019-12-09 2021-06-10 Nicoventures Trading Limited Oral products with controlled release
EP4072329A1 (en) 2019-12-09 2022-10-19 Nicoventures Trading Limited Process
EP4072301A1 (en) 2019-12-09 2022-10-19 Nicoventures Trading Limited Nanoemulsion for oral use
US11826462B2 (en) 2019-12-09 2023-11-28 Nicoventures Trading Limited Oral product with sustained flavor release
US20210169890A1 (en) 2019-12-09 2021-06-10 Nicoventures Trading Limited Oral composition with polymeric component
AU2020400386A1 (en) 2019-12-09 2022-07-07 Nicoventures Trading Limited Pouched products with heat sealable binder
US20210169868A1 (en) 2019-12-09 2021-06-10 Nicoventures Trading Limited Oral compositions with reduced water content
US20210170031A1 (en) 2019-12-09 2021-06-10 Nicoventures Trading Limited Oral composition with nanocrystalline cellulose
US20210169786A1 (en) 2019-12-09 2021-06-10 Nicoventures Trading Limited Oral composition with beet material
US20210169132A1 (en) 2019-12-09 2021-06-10 Nicoventures Trading Limited Oral composition including gels
US20210169126A1 (en) 2019-12-09 2021-06-10 Nicoventures Trading Limited Oral composition with salt inclusion
WO2021116919A1 (en) 2019-12-09 2021-06-17 Nicoventures Trading Limited Fleece for oral product with releasable component
WO2021116884A1 (en) 2019-12-09 2021-06-17 Nicoventures Trading Limited Layered fleece for pouched product
US11712059B2 (en) 2020-02-24 2023-08-01 Nicoventures Trading Limited Beaded tobacco material and related method of manufacture
WO2021250516A1 (en) 2020-06-08 2021-12-16 Nicoventures Trading Limited Effervescent oral composition comprising an active ingredient
IL299845A (en) 2020-07-15 2023-03-01 Schabar Res Associates Llc Unit oral dose compositions composed of ibuprofen and famotidine for the treatment of acute pain and the reduction of the severity and/or risk of heartburn
CA3124579A1 (en) 2020-07-15 2022-01-15 Schabar Research Associates Llc Unit oral dose compositions composed of naproxen sodium and famotidine for the treatment of acute pain and the reduction of the severity of heartburn and/or the risk of heartburn
MX2023001042A (en) 2020-07-31 2023-02-16 Procter & Gamble Water-soluble fibrous pouch containing prills for hair care.
GB202013491D0 (en) 2020-08-27 2020-10-14 Nicoventures Holdings Ltd Oral Product
US11937626B2 (en) 2020-09-04 2024-03-26 Nicoventures Trading Limited Method for whitening tobacco
CN112076165B (en) * 2020-09-08 2022-05-13 北京哈三联科技有限责任公司 Orally disintegrating tablet capable of freshening breath and preparation method thereof
US20240008522A1 (en) 2020-11-18 2024-01-11 Nicoventures Trading Limited Oral products
WO2022106923A1 (en) 2020-11-18 2022-05-27 BioPharma Synergies, S. L. Orodispersible powder composition comprising an antihistamine compound
WO2022162558A1 (en) 2021-01-28 2022-08-04 Nicoventures Trading Limited Method for sealing pouches
WO2022224196A1 (en) 2021-04-22 2022-10-27 Nicoventures Trading Limited Orally dissolving films
US20220354155A1 (en) 2021-04-30 2022-11-10 Nicoventures Trading Limited Multi-compartment oral pouched product
WO2022229929A1 (en) 2021-04-30 2022-11-03 Nicoventures Trading Limited Oral products with high-density load
WO2022234522A1 (en) 2021-05-06 2022-11-10 Nicoventures Trading Limited Oral compositions and related methods for reducing throat irritation
CA3222813A1 (en) 2021-06-16 2022-12-22 Anthony Richard Gerardi Pouched product comprising dissolvable composition
CA3223902A1 (en) 2021-06-25 2022-12-29 Richard Svensson Oral products and method of manufacture
US20230138306A1 (en) 2021-09-30 2023-05-04 Nicoventures Trading Limited Oral product with a basic amine and an ion pairing agent
FR3128880A1 (en) * 2021-11-10 2023-05-12 Strand Cosmetics Europe WATER SOLUBLE FILM FOR TOPICAL APPLICATION
US20230148652A1 (en) 2021-11-15 2023-05-18 Nicoventures Trading Limited Oral products with nicotine-polymer complex
WO2023084499A1 (en) 2021-11-15 2023-05-19 Nicoventures Trading Limited Products with enhanced sensory characteristics
US20230309603A1 (en) 2022-03-31 2023-10-05 R.J. Reynolds Tobacco Company Agglomerated botanical material for oral products
WO2023194959A1 (en) 2022-04-06 2023-10-12 Nicoventures Trading Limited Pouched products with heat sealable binder
WO2023222213A1 (en) 2022-05-18 2023-11-23 Symrise Ag Antimicrobial mixtures
WO2023248187A1 (en) 2022-06-24 2023-12-28 Nicoventures Trading Limited Oral composition comprising a receptor modulator

Family Cites Families (95)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB1142325A (en) 1965-05-14 1969-02-05 Higham Stanley Russell Means for administering drugs
US3492131A (en) 1966-04-18 1970-01-27 Searle & Co Peptide sweetening agents
DE2012775C3 (en) 1970-03-18 1973-10-04 V.P. Variopharm Gmbh Herstellung Und Vertrieb Pharmazeutischer, Kosmetischer Und Chemischer Erzeugnisse, 6656 Einoed Ointment foils and process for their manufacture
US3784390A (en) 1971-07-23 1974-01-08 Hayashibara Biochem Lab Shaped bodies of pullulan and their use
US4197289A (en) 1975-12-15 1980-04-08 Hoffmann-La Roche Inc. Novel dosage forms
US4562020A (en) * 1982-12-11 1985-12-31 Kabushiki Kaisha Hayashibara Seibutsu Kagaku Kenkyujo Process for producing self-supporting glucan film
JPS59111817A (en) * 1982-12-11 1984-06-28 Hayashibara Biochem Lab Inc Manufacture of pullulan self-supporting film
US4795436A (en) 1983-11-14 1989-01-03 Bio-Mimetics, Inc. Bioadhesive composition and method of treatment therewith
JPS60219238A (en) 1984-04-14 1985-11-01 Hayashibara Biochem Lab Inc Formed product containing slowly disintegrating pullulan and its production
EP0161681A3 (en) 1984-05-17 1987-04-29 Mitsubishi Acetate Co., Ltd. Gel plate and process for preparing same
US4843098A (en) * 1985-02-05 1989-06-27 Warner-Lambert Company Ingestible aggregate and delivery system prepared therefrom
DE3532860C1 (en) * 1985-09-14 1987-03-12 Blendax Werke Schneider Co Oral hygiene products
JPH0653657B2 (en) 1985-09-26 1994-07-20 サンスタ−株式会社 Bath agent
JPH07553B2 (en) 1985-12-09 1995-01-11 佐藤製薬株式会社 Film preparation
IL78826A (en) 1986-05-19 1991-05-12 Yissum Res Dev Co Precursor composition for the preparation of a biodegradable implant for the sustained release of an active material and such implants prepared therefrom
CA1313620C (en) 1986-08-08 1993-02-16 Yasunobu Okada Oral drug delivery systems
EP0256611A1 (en) 1986-08-08 1988-02-24 Squibb Japan Inc. Oral drug delivery systems
JPS6359855A (en) 1986-08-29 1988-03-15 Jun Kawai Edible film
DE3630603A1 (en) 1986-09-09 1988-03-10 Desitin Arzneimittel Gmbh PHARMACEUTICAL AND DOSAGE FORM FOR MEDICINAL ACTIVE SUBSTANCES, REAGENTS OR THE LIKE, AND METHOD FOR THE PRODUCTION THEREOF
JPH0739508B2 (en) 1986-11-11 1995-05-01 株式会社林原生物化学研究所 Pullulan / polyethylene glycol aggregate, its production method and use
US4923394A (en) * 1986-11-19 1990-05-08 Nippon Tansan Gas Co., Ltd. Portable torch
US4851394A (en) 1986-12-30 1989-07-25 Uni Colloid Kabushiki Kaisha Glucomannan/polyhydric alcohol composition and film prepared therefrom
JPS63250319A (en) 1987-04-06 1988-10-18 Fujimoto Seiyaku Kk Pharmaceutical preparation suitable in oral cavity
JPS63250318A (en) 1987-04-06 1988-10-18 Fujimoto Seiyaku Kk Pharmaceutical preparation suitable in oral cavity
US4820506A (en) 1987-05-01 1989-04-11 Research Foundation, State University Of New York Salivary stimulant
JPS63280014A (en) 1987-05-12 1988-11-17 Sekisui Chem Co Ltd Plaster composition for bad breath prevention
JPS63296655A (en) 1987-05-29 1988-12-02 Toppan Printing Co Ltd Production of edible sheet
US4975426A (en) 1987-06-08 1990-12-04 Analgesic Associates Cough/cold mixtures comprising non-sedating antihistamine drugs
JP2642354B2 (en) 1987-06-11 1997-08-20 株式会社 三和化学研究所 Manufacturing method of sustained release buccal
JPS63310818A (en) 1987-06-12 1988-12-19 Sato Seiyaku Kk Sheet preparation to be applied to oral mucosa
JPH01160455A (en) 1987-12-17 1989-06-23 Yoshikawa Kikai Seisakusho:Kk Feeding method of lump-like cake material and device therefor
CN1036967A (en) * 1988-02-04 1989-11-08 武田药品工业株式会社 Edible film
US5047244A (en) 1988-06-03 1991-09-10 Watson Laboratories, Inc. Mucoadhesive carrier for delivery of therapeutical agent
DE3827561C1 (en) * 1988-08-13 1989-12-28 Lts Lohmann Therapie-Systeme Gmbh & Co Kg, 5450 Neuwied, De
JPH0259513A (en) * 1988-08-24 1990-02-28 Kiyuukiyuu Yakuhin Kogyo Kk Oral cavity mucosa-attaching type halitosis-preventing agent
US5089307A (en) * 1989-05-23 1992-02-18 Mitsubishi Rayon Co., Ltd. Edible film and method of making same
US5354551A (en) 1989-10-14 1994-10-11 Desitin Arzneimittel Gmbh Oral and dental hygiene preparation
US5284659A (en) * 1990-03-30 1994-02-08 Cherukuri Subraman R Encapsulated flavor with bioadhesive character in pressed mints and confections
DE4018247A1 (en) 1990-06-07 1991-12-12 Lohmann Therapie Syst Lts MANUFACTURING METHOD FOR QUICK-DISINFITTING FILM-SHAPED PHARMACEUTICAL FORMS
GB9017800D0 (en) 1990-08-14 1990-09-26 Unilever Plc Moisture barrier and its preparation
JPH04117242A (en) * 1990-09-05 1992-04-17 Fuji Oil Co Ltd Production of nonfusible film
US5185153A (en) * 1990-10-04 1993-02-09 The Research Foundation Of The State University Of New York Agents effecting the lysis of oral bacteria
JP2785080B2 (en) 1991-02-27 1998-08-13 日清製油株式会社 Bath composition
TW209174B (en) * 1991-04-19 1993-07-11 Takeda Pharm Industry Co Ltd
JPH051198A (en) 1991-06-26 1993-01-08 Japan Happy:Kk Water-soluble film
US5141961A (en) 1991-06-27 1992-08-25 Richrdson-Vicks Inc. Process for solubilizing difficulty soluble pharmaceutical actives
JPH05236885A (en) 1991-07-17 1993-09-17 Tazawa Toshihiko Flavoring and refreshing food formed into film
JPH0541602A (en) 1991-08-06 1993-02-19 Fujitsu General Ltd Primary radiator in common use with circularly polarized wave and linearly polarized wave
US5188822A (en) * 1991-08-07 1993-02-23 Chesebrough-Pond's Usa Co., Division Of Conopco Inc. Oral compositions containing an aminosilicone and a lipophilic compound
BR9206408A (en) 1991-08-23 1994-11-22 Gillette Canada Oral brush, extended release matrix, process for releasing an antimicrobial agent from an oral brush and for releasing an antimicrobial agent in an animal's mouth and an oral wear indicator brush
US5580578A (en) * 1992-01-27 1996-12-03 Euro-Celtique, S.A. Controlled release formulations coated with aqueous dispersions of acrylic polymers
JP3232488B2 (en) 1992-08-20 2001-11-26 株式会社林原生物化学研究所 High content of pullulan, its production method and use
US5286502A (en) * 1992-04-21 1994-02-15 Wm. Wrigley Jr. Company Use of edible film to prolong chewing gum shelf life
US5411945A (en) 1992-08-29 1995-05-02 Kabushiki Kaisha Hayashibara Seibutsu Kagaku Kenkyujo Pullulan binder and its uses
CA2169729C (en) * 1993-08-19 2001-04-03 James E. Biegajski Water-soluble pressure-sensitive mucoadhesive
US5536263A (en) 1994-03-30 1996-07-16 Lectec Corporation Non-occulusive adhesive patch for applying medication to the skin
JP3313244B2 (en) * 1994-08-11 2002-08-12 三井化学株式会社 Salicylate resin and method for producing the same
US5529783A (en) 1994-12-19 1996-06-25 Mcneil-Ppc, Inc. Rotor granulation and coating of acetaminophen, pseudoephedrine, chlorpheniramine, and, optionally dextromethorphan
US5641512A (en) 1995-03-29 1997-06-24 The Procter & Gamble Company Soft gelatin capsule compositions
JPH11506769A (en) * 1995-06-05 1999-06-15 ホワイトヒル・オーラル・テクノロジー・インコーポレイテツド Products based on oral ultramulsion
EP0750905B1 (en) 1995-06-27 2003-01-02 Kao Corporation Patch comprising water soluble adhesive sheet
JPH09124512A (en) 1995-10-26 1997-05-13 Res Inst For Prod Dev Water-soluble medicine-pullulan combination preparation for targeting liver
JP2791317B2 (en) 1995-12-26 1998-08-27 株式会社三和化学研究所 Multilayer film preparation
AU1533697A (en) * 1996-01-24 1997-08-20 Warner-Lambert Company Peroxide/essential oils containing mouthwash compositions and two-part mouthwash systems
US5912007A (en) 1996-02-29 1999-06-15 Warner-Lambert Company Delivery system for the localized administration of medicaments to the upper respiratory tract and methods for preparing and using same
EP0803243B1 (en) 1996-04-24 2003-03-19 Pfizer Inc. Cyclodextrins and phenolic compounds in dental products
DK0922464T3 (en) * 1996-07-12 2005-06-06 Daiichi Seiyaku Co Quickly disintegrable, compression molded materials and processes for making the same
AU4428397A (en) * 1996-09-20 1998-04-14 Warner-Lambert Company Oral compositions containing a zinc compound
DE19646392A1 (en) * 1996-11-11 1998-05-14 Lohmann Therapie Syst Lts Preparation for use in the oral cavity with a layer containing pressure-sensitive adhesive, pharmaceuticals or cosmetics for dosed delivery
DE19652268C2 (en) 1996-12-16 2000-06-29 Lohmann Therapie Syst Lts Medicinal preparation for the release of apomorphine in the oral cavity
DE19652188C2 (en) 1996-12-16 2002-02-14 Lohmann Therapie Syst Lts Flat drug preparation for application and release of buprenorphine or a pharmacologically comparable substance in the oral cavity and process for its preparation
JPH10179451A (en) 1996-12-20 1998-07-07 Aisin Seiki Co Ltd Raising and lowering device for toilet seat with hot water washing device
JPH10179045A (en) 1996-12-25 1998-07-07 Osaka Kagaku Gokin Kk Sheet-like edible molding
US5885594A (en) * 1997-03-27 1999-03-23 The Procter & Gamble Company Oral compositions having enhanced mouth-feel
US6136297A (en) 1997-06-06 2000-10-24 The Procter & Gamble Company Delivery system for an oral care substance using a strip of material having low flexural stiffness
JPH1160455A (en) * 1997-06-13 1999-03-02 Yuusuke Nonomura Controlling agent for bacterial flora including preventing agent for dental caries and controlling
GB2328443B (en) * 1997-08-21 2001-09-05 Reckitt & Colmann Prod Ltd In situ formation of pharmaceutically acceptable polymeric material
JP3460538B2 (en) 1997-10-08 2003-10-27 救急薬品工業株式会社 Fast dissolving film preparation
CA2300205A1 (en) * 1997-12-22 1999-07-01 Warner-Lambert Company Compositions for inhibiting gingivitis
US6432442B1 (en) * 1998-02-23 2002-08-13 Mcneil-Ppc, Inc. Chewable product
US6132702A (en) * 1998-02-27 2000-10-17 The Procter & Gamble Company Oral care compositions comprising chlorite and methods
US20030211136A1 (en) * 1998-09-25 2003-11-13 Neema Kulkarni Fast dissolving orally consumable films containing a sweetener
US6596298B2 (en) * 1998-09-25 2003-07-22 Warner-Lambert Company Fast dissolving orally comsumable films
US6231957B1 (en) * 1999-05-06 2001-05-15 Horst G. Zerbe Rapidly disintegrating flavor wafer for flavor enrichment
US7067116B1 (en) * 2000-03-23 2006-06-27 Warner-Lambert Company Llc Fast dissolving orally consumable solid film containing a taste masking agent and pharmaceutically active agent at weight ratio of 1:3 to 3:1
US6372252B1 (en) * 2000-04-28 2002-04-16 Adams Laboratories, Inc. Guaifenesin sustained release formulation and tablets
US20020131990A1 (en) 2000-11-30 2002-09-19 Barkalow David G. Pullulan free edible film compositions and methods of making the same
US6656493B2 (en) 2001-07-30 2003-12-02 Wm. Wrigley Jr. Company Edible film formulations containing maltodextrin
CA2457086A1 (en) 2001-08-17 2003-02-27 Smithkline Beecham P.L.C. Oral care substance delivery strip
US6419903B1 (en) 2001-08-20 2002-07-16 Colgate Palmolive Company Breath freshening film
EP3542793A1 (en) 2001-10-12 2019-09-25 Aquestive Therapeutics, Inc. Thin film with non-self-aggregating uniform heterogeneity, process for their production and drug delivery systems made therefrom
EP2332523B8 (en) 2001-10-12 2022-04-20 Aquestive Therapeutics, Inc. Uniform films for rapid dissolve dosage form incorporating taste-masking compositions
CA2473975C (en) 2001-10-12 2011-05-03 Monosolrx Llc Glucan based film delivery systems
US20030224090A1 (en) 2002-02-11 2003-12-04 Edizone, Lc Snacks of orally soluble edible films
CA2554649C (en) * 2004-01-30 2015-10-27 Corium International, Inc. Rapidly dissolving film for delivery of an active agent

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US11571450B2 (en) 2020-06-17 2023-02-07 Psilo Scientific Ltd Aqueous extraction of psychoactive compounds from psilocybin fungus
US11642385B2 (en) 2020-06-17 2023-05-09 Psilo Scientific Ltd. Basic extraction of psychoactive compounds from psychoactive organisms
WO2022140841A1 (en) * 2020-12-28 2022-07-07 Psilo Scientific Ltd Transmucosal psychoactive alkaloid composition and preparation thereof
US11786506B2 (en) 2020-12-28 2023-10-17 Psilo Scientific Ltd Transmucosal psychoactive alkaloid composition and preparation thereof

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US20010022964A1 (en) 2001-09-20
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PE20000972A1 (en) 2000-10-02
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WO2000018365A3 (en) 2000-11-16
CY1105213T1 (en) 2010-03-03
PT1115372E (en) 2006-07-31
UY25728A1 (en) 1999-11-17
SI1115372T1 (en) 2006-10-31
EP1676557A3 (en) 2006-09-06
BR9914064B1 (en) 2011-08-23
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US7491406B2 (en) 2009-02-17
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WO2000018365A2 (en) 2000-04-06
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US20090163530A1 (en) 2009-06-25
TWI286943B (en) 2007-09-21
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BR9914064A (en) 2001-06-19
ES2260961T3 (en) 2006-11-01
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