CA2340381A1 - Methods and apparatus for in situ formation of hydrogels - Google Patents

Methods and apparatus for in situ formation of hydrogels Download PDF

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Publication number
CA2340381A1
CA2340381A1 CA002340381A CA2340381A CA2340381A1 CA 2340381 A1 CA2340381 A1 CA 2340381A1 CA 002340381 A CA002340381 A CA 002340381A CA 2340381 A CA2340381 A CA 2340381A CA 2340381 A1 CA2340381 A1 CA 2340381A1
Authority
CA
Canada
Prior art keywords
cross linking
methods
linking solutions
sprayer
solutions
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Granted
Application number
CA002340381A
Other languages
French (fr)
Other versions
CA2340381C (en
Inventor
Amarpreet S. Sawhney
Patrick K. Campbell
David A. Melanson
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Incept LLC
Original Assignee
Incept Llc
Amarpreet S. Sawhney
Patrick K. Campbell
David A. Melanson
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Priority claimed from US09/134,198 external-priority patent/US6179862B1/en
Application filed by Incept Llc, Amarpreet S. Sawhney, Patrick K. Campbell, David A. Melanson filed Critical Incept Llc
Publication of CA2340381A1 publication Critical patent/CA2340381A1/en
Application granted granted Critical
Publication of CA2340381C publication Critical patent/CA2340381C/en
Anticipated expiration legal-status Critical
Expired - Lifetime legal-status Critical Current

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B17/00—Surgical instruments, devices or methods, e.g. tourniquets
    • A61B17/00491—Surgical glue applicators
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M35/00—Devices for applying media, e.g. remedies, on the human body
    • A61M35/30—Gas therapy for therapeutic treatment of the skin
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B17/00—Surgical instruments, devices or methods, e.g. tourniquets
    • A61B17/00491—Surgical glue applicators
    • A61B2017/00495—Surgical glue applicators for two-component glue
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M25/00—Catheters; Hollow probes
    • A61M25/0067—Catheters; Hollow probes characterised by the distal end, e.g. tips
    • A61M25/0068—Static characteristics of the catheter tip, e.g. shape, atraumatic tip, curved tip or tip structure
    • A61M25/0071—Multiple separate lumens

Abstract

Methods, and apparatus of forming in situ tissue adherent barriers are provided using a sprayer (90) capable of applying two or more viscous cross linking solutions to tissue. The sprayer (90) comprises separate spray nozzles (98, 100) for each of two or more cross linking solutions, wherein each nozzle (98, 100) is in communication with a gas pressurized chamber (48) also may include valves (52) that prevent back flow through the supply lines (99, 101) carrying the cross linking solutions, and a venting system (106, 108) for venting excess pressure for laparoscopic applications. In the presence of gas flow, the cross linking solutions are atomized, and mixed to form a spray. Multi-component hydrogel systems suitable for use with the inventive methods, and apparatus are also described.
CA002340381A 1998-08-14 1999-08-13 Methods and apparatus for in situ formation of hydrogels Expired - Lifetime CA2340381C (en)

Applications Claiming Priority (5)

Application Number Priority Date Filing Date Title
US09/134,198 US6179862B1 (en) 1998-08-14 1998-08-14 Methods and apparatus for in situ formation of hydrogels
US10827398P 1998-11-12 1998-11-12
US09/134,198 1998-11-12
US60/108,273 1998-11-12
PCT/US1999/018446 WO2000009199A1 (en) 1998-08-14 1999-08-13 Methods and apparatus for in situ formation of hydrogels

Publications (2)

Publication Number Publication Date
CA2340381A1 true CA2340381A1 (en) 2000-02-24
CA2340381C CA2340381C (en) 2009-01-13

Family

ID=26805729

Family Applications (1)

Application Number Title Priority Date Filing Date
CA002340381A Expired - Lifetime CA2340381C (en) 1998-08-14 1999-08-13 Methods and apparatus for in situ formation of hydrogels

Country Status (8)

Country Link
US (1) US6165201A (en)
EP (1) EP1104324B8 (en)
JP (1) JP4159254B2 (en)
AT (1) ATE502670T1 (en)
AU (1) AU5560899A (en)
CA (1) CA2340381C (en)
DE (1) DE69943297D1 (en)
WO (1) WO2000009199A1 (en)

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