CA2342023A1 - Paramagnetic particle detection - Google Patents

Paramagnetic particle detection Download PDF

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Publication number
CA2342023A1
CA2342023A1 CA002342023A CA2342023A CA2342023A1 CA 2342023 A1 CA2342023 A1 CA 2342023A1 CA 002342023 A CA002342023 A CA 002342023A CA 2342023 A CA2342023 A CA 2342023A CA 2342023 A1 CA2342023 A1 CA 2342023A1
Authority
CA
Canada
Prior art keywords
sample
particle detection
paramagnetic particle
coil
exposed
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Granted
Application number
CA002342023A
Other languages
French (fr)
Other versions
CA2342023C (en
Inventor
Peter Hawkins
Richard William Luxton
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Randox Laboratories Ltd
Original Assignee
Randox Laboratories Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Randox Laboratories Ltd filed Critical Randox Laboratories Ltd
Publication of CA2342023A1 publication Critical patent/CA2342023A1/en
Application granted granted Critical
Publication of CA2342023C publication Critical patent/CA2342023C/en
Anticipated expiration legal-status Critical
Expired - Fee Related legal-status Critical Current

Links

Classifications

    • GPHYSICS
    • G01MEASURING; TESTING
    • G01RMEASURING ELECTRIC VARIABLES; MEASURING MAGNETIC VARIABLES
    • G01R33/00Arrangements or instruments for measuring magnetic variables
    • G01R33/12Measuring magnetic properties of articles or specimens of solids or fluids
    • G01R33/1223Measuring permeability, i.e. permeameters
    • YGENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10TECHNICAL SUBJECTS COVERED BY FORMER USPC
    • Y10STECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10S436/00Chemistry: analytical and immunological testing
    • Y10S436/804Radioisotope, e.g. radioimmunoassay

Abstract

A method of determining the number of magnetic particles within a sample using a tuned circuit having a capacitor and a coil. The method comprises: a. determini:ng the difference in the resonant frequency of the tuned circuit when the sample is exposed to a magnetic field generated by the coil and when the sample is not exposed to the magnetic field generated by the coil; and b. using the difference in the resonant frequency to determine the number of magnetic particles within the sample.
CA002342023A 2000-04-10 2001-03-26 Paramagnetic particle detection Expired - Fee Related CA2342023C (en)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
EP00302993.1 2000-04-10
EP00302993 2000-04-10

Publications (2)

Publication Number Publication Date
CA2342023A1 true CA2342023A1 (en) 2001-10-10
CA2342023C CA2342023C (en) 2007-07-03

Family

ID=8172903

Family Applications (1)

Application Number Title Priority Date Filing Date
CA002342023A Expired - Fee Related CA2342023C (en) 2000-04-10 2001-03-26 Paramagnetic particle detection

Country Status (10)

Country Link
US (1) US7241630B2 (en)
JP (1) JP2002005892A (en)
CN (1) CN1208621C (en)
AR (1) AR027785A1 (en)
AT (1) ATE300743T1 (en)
AU (1) AU770502B2 (en)
BR (1) BR0101432A (en)
CA (1) CA2342023C (en)
DE (1) DE60112159T2 (en)
MX (1) MXPA01003640A (en)

Cited By (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP2535712A1 (en) 2011-06-15 2012-12-19 F. Hoffmann-La Roche AG Analytical system for the preparation of biological material

Families Citing this family (20)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB0124341D0 (en) * 2001-10-10 2001-11-28 Randox Lab Ltd Assay
JP3682459B1 (en) * 2004-03-26 2005-08-10 株式会社ディーゼルユナイテッド Magnetic substance concentration measuring device, detection sensitivity improvement method, zero point compensation method, and zero point correction method
JP3682460B1 (en) * 2004-04-09 2005-08-10 株式会社ディーゼルユナイテッド Athletic institution
JP4731927B2 (en) * 2005-01-31 2011-07-27 キヤノン株式会社 Magnetic sensor and detection kit
FI20065257A0 (en) * 2006-04-21 2006-04-21 Magnasense Oy Arrangement and method for measuring magnetic particles
FI121248B (en) * 2006-04-21 2010-08-31 Magnasense Technologies Oy Device for measuring magnetic particles and the corresponding method
RU2444736C2 (en) * 2006-05-09 2012-03-10 Конинклейке Филипс Электроникс Н.В. Target molecule detection in sample
US8725245B2 (en) * 2006-08-14 2014-05-13 Kimberly-Clark Worldwide, Inc. Resonant coil for measuring specimen condition
US7755351B2 (en) * 2007-01-23 2010-07-13 The Boeing Company Method and apparatus for detecting inconsistencies in fiber reinforced resin parts using eddy currents
CA2682211A1 (en) * 2007-03-21 2008-09-25 University Of The West Of England, Bristol Particle facilitated testing
US7768257B2 (en) * 2007-05-17 2010-08-03 Alcotek, Inc. Systems and methods for determining the position of an electrical solenoid
SE532617C2 (en) * 2007-11-13 2010-03-02 Lifeassays Ab Publ Magnetic detector coil mechanism
CN101903760A (en) * 2007-12-20 2010-12-01 皇家飞利浦电子股份有限公司 Positioning of magnetic coils in a sensor device
WO2009148668A2 (en) * 2008-03-07 2009-12-10 California Institute Of Technology Effective-inductance-change based magnetic particle sensing
CN102246034B (en) * 2008-09-15 2014-03-12 加利福尼亚技术学院 Frequency-shift CMOS magnetic biosensor array with single bead sensitivity and no external magnet
US9599591B2 (en) 2009-03-06 2017-03-21 California Institute Of Technology Low cost, portable sensor for molecular assays
TWI404340B (en) * 2009-11-23 2013-08-01 Mstar Semiconductor Inc Offset phase-locked loop transmitter and method thereof
US9778225B2 (en) 2010-11-15 2017-10-03 Regents Of The University Of Minnesota Magnetic search coil for measuring real-time brownian relaxation of magnetic nanoparticles
DE102013109467A1 (en) * 2013-08-30 2015-03-05 MRB Forschungszentrum für Magnet - Resonanz - Bayern e.V. Method and device for analyzing a sample volume comprising magnetic particles
JP6291635B2 (en) * 2014-02-10 2018-03-14 弘美 西村 Metal material identification device

Family Cites Families (25)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US3858111A (en) * 1970-11-02 1974-12-31 Singer Co Method and apparatus for sensing chemical process concentrations
US3719882A (en) * 1970-11-12 1973-03-06 A Pincus Resonant circuit apparatus for detecting electromagnetic conductive bodies
JPS5414242A (en) * 1977-07-04 1979-02-02 Hitachi Ltd Measuring method for toner concentration in developer
US4314821A (en) * 1979-04-09 1982-02-09 Minnesota Mining And Manufacturing Company Sandwich immunoassay using piezoelectric oscillator
JPS6390765A (en) * 1986-10-03 1988-04-21 Nippon Telegr & Teleph Corp <Ntt> Squid immunoassay
US4912976A (en) * 1987-06-26 1990-04-03 Beckman Instruments, Inc. Liquid level sensing apparatus
US5679342A (en) * 1987-11-18 1997-10-21 Chiron Corporation Hepatitis C virus infected cell systems
JPH02133689A (en) * 1988-11-14 1990-05-22 Mitsubishi Heavy Ind Ltd Twin-wire former of paper-making machine
DE3900413A1 (en) 1989-01-09 1990-07-12 N Proizv Ob Abrazivam I Slifov DEVICE FOR MEASURING THE CONTENT OF MAGNETIC COMPONENTS OF NON-METAL SAMPLES
JP2847788B2 (en) * 1989-08-11 1999-01-20 日本電気株式会社 Measuring device for cement content in cement mixture
JPH03269256A (en) * 1990-03-19 1991-11-29 Nec Corp Measuring apparatus for amount of cement in cement mixture
JPH05172781A (en) * 1991-12-26 1993-07-09 Hitachi Metals Ltd Differential amplification type toner sensor
JP2981951B2 (en) * 1992-06-23 1999-11-22 株式会社新川 Wire bonding equipment
JPH0653823A (en) * 1992-07-31 1994-02-25 Matsushita Electric Ind Co Ltd Synthesizer device
US5493922A (en) * 1993-07-09 1996-02-27 Akzo N.V. Liquid level sensing probe and control circuit
US5528142A (en) 1995-06-19 1996-06-18 Feickert; Carl A. Resonant eddy analysis- a contactless, inductive method for deriving quantitative information about the conductivity and permeability of a test sample
JP3248832B2 (en) 1995-08-31 2002-01-21 三菱電機株式会社 Sensor circuit
JP3749959B2 (en) * 1996-02-26 2006-03-01 株式会社シノテスト Measuring method of test substance using magnetic particles and measuring instrument used for the method
JPH1062390A (en) * 1996-08-23 1998-03-06 Konica Corp Toner concentration detector of image forming device
US5922537A (en) 1996-11-08 1999-07-13 N.o slashed.AB Immunoassay, Inc. Nanoparticles biosensor
US5981297A (en) * 1997-02-05 1999-11-09 The United States Of America As Represented By The Secretary Of The Navy Biosensor using magnetically-detected label
US5978694A (en) 1997-02-27 1999-11-02 Uri Rapoport Method and apparatus for detecting a magnetically responsive substance
US6046585A (en) * 1997-11-21 2000-04-04 Quantum Design, Inc. Method and apparatus for making quantitative measurements of localized accumulations of target particles having magnetic particles bound thereto
US6100660A (en) * 1998-03-30 2000-08-08 Aisin Seiki Kabushiki Kaisha Current supply controller for an electric motor
DE19929178C2 (en) * 1999-06-25 2002-10-24 Infineon Technologies Ag Phase locked loop system

Cited By (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP2535712A1 (en) 2011-06-15 2012-12-19 F. Hoffmann-La Roche AG Analytical system for the preparation of biological material

Also Published As

Publication number Publication date
BR0101432A (en) 2001-12-26
ATE300743T1 (en) 2005-08-15
MXPA01003640A (en) 2005-06-30
AR027785A1 (en) 2003-04-09
CN1208621C (en) 2005-06-29
JP2002005892A (en) 2002-01-09
CN1317693A (en) 2001-10-17
US20010050555A1 (en) 2001-12-13
CA2342023C (en) 2007-07-03
US7241630B2 (en) 2007-07-10
DE60112159D1 (en) 2005-09-01
AU770502B2 (en) 2004-02-26
AU3136501A (en) 2001-10-11
DE60112159T2 (en) 2006-04-27

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EEER Examination request
MKLA Lapsed

Effective date: 20180326