CA2362439A1 - Endoluminal cardiac and venous valve prostheses and methods of manufacture and delivery thereof - Google Patents

Endoluminal cardiac and venous valve prostheses and methods of manufacture and delivery thereof Download PDF

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Publication number
CA2362439A1
CA2362439A1 CA002362439A CA2362439A CA2362439A1 CA 2362439 A1 CA2362439 A1 CA 2362439A1 CA 002362439 A CA002362439 A CA 002362439A CA 2362439 A CA2362439 A CA 2362439A CA 2362439 A1 CA2362439 A1 CA 2362439A1
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CA
Canada
Prior art keywords
stent body
body member
section
prosthesis according
valvular prosthesis
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Granted
Application number
CA002362439A
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French (fr)
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CA2362439C (en
Inventor
Steven R. Bailey
Christopher T. Boyle
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ABPS Venture One Ltd
Original Assignee
Steven R. Bailey
Christopher T. Boyle
Abps Venture One, Ltd.
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Publication of CA2362439A1 publication Critical patent/CA2362439A1/en
Application granted granted Critical
Publication of CA2362439C publication Critical patent/CA2362439C/en
Anticipated expiration legal-status Critical
Expired - Lifetime legal-status Critical Current

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Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61F—FILTERS IMPLANTABLE INTO BLOOD VESSELS; PROSTHESES; DEVICES PROVIDING PATENCY TO, OR PREVENTING COLLAPSING OF, TUBULAR STRUCTURES OF THE BODY, e.g. STENTS; ORTHOPAEDIC, NURSING OR CONTRACEPTIVE DEVICES; FOMENTATION; TREATMENT OR PROTECTION OF EYES OR EARS; BANDAGES, DRESSINGS OR ABSORBENT PADS; FIRST-AID KITS
    • A61F2/00—Filters implantable into blood vessels; Prostheses, i.e. artificial substitutes or replacements for parts of the body; Appliances for connecting them with the body; Devices providing patency to, or preventing collapsing of, tubular structures of the body, e.g. stents
    • A61F2/02—Prostheses implantable into the body
    • A61F2/24—Heart valves ; Vascular valves, e.g. venous valves; Heart implants, e.g. passive devices for improving the function of the native valve or the heart muscle; Transmyocardial revascularisation [TMR] devices; Valves implantable in the body
    • A61F2/2412—Heart valves ; Vascular valves, e.g. venous valves; Heart implants, e.g. passive devices for improving the function of the native valve or the heart muscle; Transmyocardial revascularisation [TMR] devices; Valves implantable in the body with soft flexible valve members, e.g. tissue valves shaped like natural valves
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61F—FILTERS IMPLANTABLE INTO BLOOD VESSELS; PROSTHESES; DEVICES PROVIDING PATENCY TO, OR PREVENTING COLLAPSING OF, TUBULAR STRUCTURES OF THE BODY, e.g. STENTS; ORTHOPAEDIC, NURSING OR CONTRACEPTIVE DEVICES; FOMENTATION; TREATMENT OR PROTECTION OF EYES OR EARS; BANDAGES, DRESSINGS OR ABSORBENT PADS; FIRST-AID KITS
    • A61F2/00—Filters implantable into blood vessels; Prostheses, i.e. artificial substitutes or replacements for parts of the body; Appliances for connecting them with the body; Devices providing patency to, or preventing collapsing of, tubular structures of the body, e.g. stents
    • A61F2/02—Prostheses implantable into the body
    • A61F2/04—Hollow or tubular parts of organs, e.g. bladders, tracheae, bronchi or bile ducts
    • A61F2/06—Blood vessels
    • A61F2/07—Stent-grafts
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61F—FILTERS IMPLANTABLE INTO BLOOD VESSELS; PROSTHESES; DEVICES PROVIDING PATENCY TO, OR PREVENTING COLLAPSING OF, TUBULAR STRUCTURES OF THE BODY, e.g. STENTS; ORTHOPAEDIC, NURSING OR CONTRACEPTIVE DEVICES; FOMENTATION; TREATMENT OR PROTECTION OF EYES OR EARS; BANDAGES, DRESSINGS OR ABSORBENT PADS; FIRST-AID KITS
    • A61F2/00—Filters implantable into blood vessels; Prostheses, i.e. artificial substitutes or replacements for parts of the body; Appliances for connecting them with the body; Devices providing patency to, or preventing collapsing of, tubular structures of the body, e.g. stents
    • A61F2/02—Prostheses implantable into the body
    • A61F2/24—Heart valves ; Vascular valves, e.g. venous valves; Heart implants, e.g. passive devices for improving the function of the native valve or the heart muscle; Transmyocardial revascularisation [TMR] devices; Valves implantable in the body
    • A61F2/2412—Heart valves ; Vascular valves, e.g. venous valves; Heart implants, e.g. passive devices for improving the function of the native valve or the heart muscle; Transmyocardial revascularisation [TMR] devices; Valves implantable in the body with soft flexible valve members, e.g. tissue valves shaped like natural valves
    • A61F2/2418—Scaffolds therefor, e.g. support stents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61F—FILTERS IMPLANTABLE INTO BLOOD VESSELS; PROSTHESES; DEVICES PROVIDING PATENCY TO, OR PREVENTING COLLAPSING OF, TUBULAR STRUCTURES OF THE BODY, e.g. STENTS; ORTHOPAEDIC, NURSING OR CONTRACEPTIVE DEVICES; FOMENTATION; TREATMENT OR PROTECTION OF EYES OR EARS; BANDAGES, DRESSINGS OR ABSORBENT PADS; FIRST-AID KITS
    • A61F2/00—Filters implantable into blood vessels; Prostheses, i.e. artificial substitutes or replacements for parts of the body; Appliances for connecting them with the body; Devices providing patency to, or preventing collapsing of, tubular structures of the body, e.g. stents
    • A61F2/02—Prostheses implantable into the body
    • A61F2/24—Heart valves ; Vascular valves, e.g. venous valves; Heart implants, e.g. passive devices for improving the function of the native valve or the heart muscle; Transmyocardial revascularisation [TMR] devices; Valves implantable in the body
    • A61F2/2427—Devices for manipulating or deploying heart valves during implantation
    • A61F2/243—Deployment by mechanical expansion
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61F—FILTERS IMPLANTABLE INTO BLOOD VESSELS; PROSTHESES; DEVICES PROVIDING PATENCY TO, OR PREVENTING COLLAPSING OF, TUBULAR STRUCTURES OF THE BODY, e.g. STENTS; ORTHOPAEDIC, NURSING OR CONTRACEPTIVE DEVICES; FOMENTATION; TREATMENT OR PROTECTION OF EYES OR EARS; BANDAGES, DRESSINGS OR ABSORBENT PADS; FIRST-AID KITS
    • A61F2/00—Filters implantable into blood vessels; Prostheses, i.e. artificial substitutes or replacements for parts of the body; Appliances for connecting them with the body; Devices providing patency to, or preventing collapsing of, tubular structures of the body, e.g. stents
    • A61F2/02—Prostheses implantable into the body
    • A61F2/24—Heart valves ; Vascular valves, e.g. venous valves; Heart implants, e.g. passive devices for improving the function of the native valve or the heart muscle; Transmyocardial revascularisation [TMR] devices; Valves implantable in the body
    • A61F2/2427—Devices for manipulating or deploying heart valves during implantation
    • A61F2/2436—Deployment by retracting a sheath
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61F—FILTERS IMPLANTABLE INTO BLOOD VESSELS; PROSTHESES; DEVICES PROVIDING PATENCY TO, OR PREVENTING COLLAPSING OF, TUBULAR STRUCTURES OF THE BODY, e.g. STENTS; ORTHOPAEDIC, NURSING OR CONTRACEPTIVE DEVICES; FOMENTATION; TREATMENT OR PROTECTION OF EYES OR EARS; BANDAGES, DRESSINGS OR ABSORBENT PADS; FIRST-AID KITS
    • A61F2/00—Filters implantable into blood vessels; Prostheses, i.e. artificial substitutes or replacements for parts of the body; Appliances for connecting them with the body; Devices providing patency to, or preventing collapsing of, tubular structures of the body, e.g. stents
    • A61F2/02—Prostheses implantable into the body
    • A61F2/24—Heart valves ; Vascular valves, e.g. venous valves; Heart implants, e.g. passive devices for improving the function of the native valve or the heart muscle; Transmyocardial revascularisation [TMR] devices; Valves implantable in the body
    • A61F2/2469—Heart valves ; Vascular valves, e.g. venous valves; Heart implants, e.g. passive devices for improving the function of the native valve or the heart muscle; Transmyocardial revascularisation [TMR] devices; Valves implantable in the body with resilient valve members, e.g. conical spiral
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61F—FILTERS IMPLANTABLE INTO BLOOD VESSELS; PROSTHESES; DEVICES PROVIDING PATENCY TO, OR PREVENTING COLLAPSING OF, TUBULAR STRUCTURES OF THE BODY, e.g. STENTS; ORTHOPAEDIC, NURSING OR CONTRACEPTIVE DEVICES; FOMENTATION; TREATMENT OR PROTECTION OF EYES OR EARS; BANDAGES, DRESSINGS OR ABSORBENT PADS; FIRST-AID KITS
    • A61F2/00—Filters implantable into blood vessels; Prostheses, i.e. artificial substitutes or replacements for parts of the body; Appliances for connecting them with the body; Devices providing patency to, or preventing collapsing of, tubular structures of the body, e.g. stents
    • A61F2/02—Prostheses implantable into the body
    • A61F2/24—Heart valves ; Vascular valves, e.g. venous valves; Heart implants, e.g. passive devices for improving the function of the native valve or the heart muscle; Transmyocardial revascularisation [TMR] devices; Valves implantable in the body
    • A61F2/2475—Venous valves
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61F—FILTERS IMPLANTABLE INTO BLOOD VESSELS; PROSTHESES; DEVICES PROVIDING PATENCY TO, OR PREVENTING COLLAPSING OF, TUBULAR STRUCTURES OF THE BODY, e.g. STENTS; ORTHOPAEDIC, NURSING OR CONTRACEPTIVE DEVICES; FOMENTATION; TREATMENT OR PROTECTION OF EYES OR EARS; BANDAGES, DRESSINGS OR ABSORBENT PADS; FIRST-AID KITS
    • A61F2/00—Filters implantable into blood vessels; Prostheses, i.e. artificial substitutes or replacements for parts of the body; Appliances for connecting them with the body; Devices providing patency to, or preventing collapsing of, tubular structures of the body, e.g. stents
    • A61F2/95—Instruments specially adapted for placement or removal of stents or stent-grafts
    • A61F2/9522—Means for mounting a stent or stent-graft onto or into a placement instrument
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61F—FILTERS IMPLANTABLE INTO BLOOD VESSELS; PROSTHESES; DEVICES PROVIDING PATENCY TO, OR PREVENTING COLLAPSING OF, TUBULAR STRUCTURES OF THE BODY, e.g. STENTS; ORTHOPAEDIC, NURSING OR CONTRACEPTIVE DEVICES; FOMENTATION; TREATMENT OR PROTECTION OF EYES OR EARS; BANDAGES, DRESSINGS OR ABSORBENT PADS; FIRST-AID KITS
    • A61F2/00—Filters implantable into blood vessels; Prostheses, i.e. artificial substitutes or replacements for parts of the body; Appliances for connecting them with the body; Devices providing patency to, or preventing collapsing of, tubular structures of the body, e.g. stents
    • A61F2/95—Instruments specially adapted for placement or removal of stents or stent-grafts
    • A61F2/958—Inflatable balloons for placing stents or stent-grafts
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61F—FILTERS IMPLANTABLE INTO BLOOD VESSELS; PROSTHESES; DEVICES PROVIDING PATENCY TO, OR PREVENTING COLLAPSING OF, TUBULAR STRUCTURES OF THE BODY, e.g. STENTS; ORTHOPAEDIC, NURSING OR CONTRACEPTIVE DEVICES; FOMENTATION; TREATMENT OR PROTECTION OF EYES OR EARS; BANDAGES, DRESSINGS OR ABSORBENT PADS; FIRST-AID KITS
    • A61F2220/00—Fixations or connections for prostheses classified in groups A61F2/00 - A61F2/26 or A61F2/82 or A61F9/00 or A61F11/00 or subgroups thereof
    • A61F2220/0008—Fixation appliances for connecting prostheses to the body
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61F—FILTERS IMPLANTABLE INTO BLOOD VESSELS; PROSTHESES; DEVICES PROVIDING PATENCY TO, OR PREVENTING COLLAPSING OF, TUBULAR STRUCTURES OF THE BODY, e.g. STENTS; ORTHOPAEDIC, NURSING OR CONTRACEPTIVE DEVICES; FOMENTATION; TREATMENT OR PROTECTION OF EYES OR EARS; BANDAGES, DRESSINGS OR ABSORBENT PADS; FIRST-AID KITS
    • A61F2220/00—Fixations or connections for prostheses classified in groups A61F2/00 - A61F2/26 or A61F2/82 or A61F9/00 or A61F11/00 or subgroups thereof
    • A61F2220/0008—Fixation appliances for connecting prostheses to the body
    • A61F2220/0016—Fixation appliances for connecting prostheses to the body with sharp anchoring protrusions, e.g. barbs, pins, spikes
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61F—FILTERS IMPLANTABLE INTO BLOOD VESSELS; PROSTHESES; DEVICES PROVIDING PATENCY TO, OR PREVENTING COLLAPSING OF, TUBULAR STRUCTURES OF THE BODY, e.g. STENTS; ORTHOPAEDIC, NURSING OR CONTRACEPTIVE DEVICES; FOMENTATION; TREATMENT OR PROTECTION OF EYES OR EARS; BANDAGES, DRESSINGS OR ABSORBENT PADS; FIRST-AID KITS
    • A61F2230/00—Geometry of prostheses classified in groups A61F2/00 - A61F2/26 or A61F2/82 or A61F9/00 or A61F11/00 or subgroups thereof
    • A61F2230/0002—Two-dimensional shapes, e.g. cross-sections
    • A61F2230/0028—Shapes in the form of latin or greek characters
    • A61F2230/005—Rosette-shaped, e.g. star-shaped
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61F—FILTERS IMPLANTABLE INTO BLOOD VESSELS; PROSTHESES; DEVICES PROVIDING PATENCY TO, OR PREVENTING COLLAPSING OF, TUBULAR STRUCTURES OF THE BODY, e.g. STENTS; ORTHOPAEDIC, NURSING OR CONTRACEPTIVE DEVICES; FOMENTATION; TREATMENT OR PROTECTION OF EYES OR EARS; BANDAGES, DRESSINGS OR ABSORBENT PADS; FIRST-AID KITS
    • A61F2230/00—Geometry of prostheses classified in groups A61F2/00 - A61F2/26 or A61F2/82 or A61F9/00 or A61F11/00 or subgroups thereof
    • A61F2230/0002—Two-dimensional shapes, e.g. cross-sections
    • A61F2230/0028—Shapes in the form of latin or greek characters
    • A61F2230/0054—V-shaped
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61F—FILTERS IMPLANTABLE INTO BLOOD VESSELS; PROSTHESES; DEVICES PROVIDING PATENCY TO, OR PREVENTING COLLAPSING OF, TUBULAR STRUCTURES OF THE BODY, e.g. STENTS; ORTHOPAEDIC, NURSING OR CONTRACEPTIVE DEVICES; FOMENTATION; TREATMENT OR PROTECTION OF EYES OR EARS; BANDAGES, DRESSINGS OR ABSORBENT PADS; FIRST-AID KITS
    • A61F2230/00—Geometry of prostheses classified in groups A61F2/00 - A61F2/26 or A61F2/82 or A61F9/00 or A61F11/00 or subgroups thereof
    • A61F2230/0063—Three-dimensional shapes
    • A61F2230/0073—Quadric-shaped
    • A61F2230/0078—Quadric-shaped hyperboloidal

Abstract

This invention relates to prosthetic cardiac and venous valves and a single catheter device and minimally invasive techniques for percutaneous and transluminal valvuloplasty and prosthetic valve implantation.

Claims (38)

1. An implantable valvular prosthesis, comprising:
a. a stent body member having lumenal and ablumenal surfaces thereof and a central annular opening along a central longitudinal axis of the stent body member;
b. a graft member covering at least a portion of at least one of the lumenal and ablumenal surfaces of the stent body member;
c. at least one biasing arm projecting from the stent body member and into the central annular opening of the stent body member; and d. at least one valve flap member coupled to the at least one biasing arm and to at least a portion of the graft member, the at least one valve flap member assuming a position, under zero pressure differential across the prosthesis, which occludes the central annular opening of the stent body member.
2. The implantable valvular prosthesis according to Claim 1, wherein the stent body member further comprises a proximal anchoring section.
3. The implantable valvular prosthesis according to Claim 1, wherein the stent body member further comprises a distal anchoring section.
4. The implantable valvular prosthesis according to Claim 2, wherein the stent body further comprises a distal anchoring section.
5. The implantable valvular prosthesis according to Claim 2, wherein the proximal anchoring section further comprises a plurality of stent struts which project radially outward away from the central longitudinal axis of the stent body member.
6. The implantable valvular prosthesis according to Claim 3, wherein the distal anchoring section further comprises a radially enlarged section of the stent body member which communicates with the central annular opening of the stent body member.
7. The implantable valvular prosthesis according to Claim 1, wherein the graft member further comprises an outer graft member coupled to the ablumenal surface of the stent body member.
8. The implantable valvular prosthesis according to Claim 1, wherein the graft member further comprises an inner graft member coupled to the lumenal surface of the stent body member.
9. The implantable valvular prosthesis according to Claim 7, wherein the graft member further comprises an inner graft member coupled to the lumenal surface of the stent body member.
10. The implantable valvular prosthesis according to Claim 9, wherein a terminal portion of the inner graft member is everted inwardly toward the central longitudinal axis of the stent body member and coupled at the eversions to the biasing arms to form the valve flap members.
11. The implantable valvular prosthesis according to Claim 10, wherein the at least one valve flap member comprise a plurality of valve flap members coupled at portions thereof to the luminal surface of the inner graft member.
12. The implantable valvular prosthesis according to Claim 11, wherein the plurality of valve flap members are coupled at equidistantly spaced intervals about the luminal surface of the inner graft member.
13. The implantable valvular prosthesis according to Claim 4, wherein the distal anchor section further comprises a diametrically enlarged section of the stent body member.
14. The implantable valvular prosthesis according to Claim 13, wherein the stent body member further comprises a flared transition section interdisposed between and interconnecting the intermediate annular section of the stent body member and the distal anchor section of the stent body member, the flared transition section projecting radially outward from the central longitudinal axis of the stent body member.
15. The implantable valvular prosthesis according to Claim 13, wherein the proximal anchor section further comprises a flange which projects radially outward and away from the central longitudinal axis of the stent body member.
16. The implantable valvular prosthesis according to Claim 15, wherein the flange projects substantially perpendicular to the central longitudinal axis of the stent body member.
17. The implantable valvular prosthesis according to Claim 13, wherein the proximal anchor section further comprises a diametrically enlarged section of the stent body member.
18. The implantable valvular prosthesis according to Claim 17, wherein the stent body member further comprises a flared transition section interdisposed between and interconnecting the intermediate annular section of the stent body member and the proximal anchor section anchor section of the stent body member, the flared transition section projecting radially outward from the central longitudinal axis of the stent body member.
19. The implantable valvular prosthesis according to Claim 14, wherein the proximal anchor section comprise a diametrically enlarged section of the stent body member and the stent body member further comprises a flared transition section interdisposed between and interconnecting the intermediate annular section of the stent body member and the proximal anchor section of the stent body member, the flared transition section projecting radially outward from the central longitudinal axis of the stent body member.
20. The implantable valvular prosthesis according to Claim 4, wherein proximal and the distal anchor sections of the stent body member each further comprise a flange which projects radially outward and away from the central longitudinal axis of the stent body member.
21. The implantable valvular prosthesis according to Claim 20, wherein the flanges of each of the proximal and distal anchor section of the stent body member project substantially perpendicular to the central longitudinal axis of the stent body member.
22. The implantable valvular prosthesis according to Claim 4, wherein the each of the proximal and the distal anchor sections further comprise diametrically enlarged sections of the stent body member.
23. The implantable valvular prosthesis according to Claim 22, wherein the stent body member further comprises proximal and distal flared transition sections interdisposed between and interconnecting opposing ends of the intermediate annular section of the stent body member and the proximal and distal anchor section anchor section of the stent body member, respectively, the flared transition sections projecting radially outward from the central longitudinal axis of the stent body member.
24. The implantable valvular prosthesis according to Claim 1, wherein the at least one biasing arm has a length which is greater than a length of a radius of the central annular opening of the stent body member.
25. The implantable valvular prosthesis according to Claim 15, wherein the flange further comprises an oriented opening in the flange.
26. An implantable valvular prosthesis, comprising:
a. a tubular stent body member comprising a plurality of spaced struts with interstices intermediate adjacent pairs of struts, the tubular stent body having lumenal and ablumenal surfaces thereof, a central annular opening along a central longitudinal axis of the stent body member, a proximal anchor section, a distal anchor section and an intermediate annular section;
b. a graft member covering at least a portion of at least one of the lumenal and ablumenal surfaces of the stent body member;
c. biasing arms projecting from the stent body member at a proximal end of the intermediate annular section and into the central annular opening of the stent body member; and d. valve flap members coupled to the biasing arms and to at least a portion of the graft member, the valve flap members assuming a closed position under zero strain load conditions.
27. The implantable valvular prosthesis according to Claim 26, wherein proximal and the distal anchor sections of the stent body member each further comprise a flange which projects radially outward and away from the central longitudinal axis of the stent body member.
28. The implantable valvular prosthesis according to Claim 27, wherein the flanges of each of the proximal and distal anchor section of the stent body member project substantially perpendicular to the central longitudinal axis of the stent body member.
29. The implantable valvular prosthesis according to Claim 26, wherein the each of the proximal and the distal anchor sections further comprise diametrically enlarged sections of the stent body member.
30. The implantable valvular prosthesis according to Claim 29, wherein the stent body member further comprises proximal and distal transition sections interdisposed between and interconnecting opposing ends of the intermediate annular section of the stent body member and the proximal and distal anchor section anchor section of the stent body member, respectively, the transition sections projecting radially outward from the central longitudinal axis of the stent body member.
31. The implantable valvular prosthesis according to Claim 26, wherein the proximal anchor section further comprises a flange section which projects radially outward from the stent body member away from the central longitudinal axis of the stent body member, and distal anchor section further comprises a diametrically enlarged section of the stent body member.
32. The implantable valvular prosthesis according to Claim 31, further comprising a transition section intermediate the distal anchor section and the intermediate annular section.
33. The implantable valvular prosthesis according to Claim 31, wherein the flange section projects substantially perpendicular away from the central longitudinal axis of the stent body member.
34. A catheter, comprising:
a. a catheter body defining a central longitudinal lumen;
b. an inflatable balloon positioned proximate the distal end of the catheter body and in fluid flow communication with the central longitudinal lumen;

c. a sheath positioned proximate the distal end of the catheter, distal the inflatable balloon and fixedly coupled to the catheter body and distally extensible therefrom;
d. a guidewire shaft positioned co-axially within the central longitudinal lumen of the catheter body and passing through an entire longitudinal length of the catheter body; and e. an annular plug member concentrically coupled to the guidewire shaft and positioned distal the inflatable balloon and proximal the sheath, the annular plug member terminating the central longitudinal lumen of the catheter body in a fluid tight manner and being moveable therein.
35. The catheter of Claim 34, further comprising a valve stent member, in a reduced diametric state, positioned within the sheath and concentrically about the guidewire shaft and distal the annular plug member.
36. A method of endoluminally delivering a valve stent within an anatomic passageway, comprising the steps of:
a. percutaneously passing a catheter endoluminally through an anatomic passageway to a valued anatomic situs within a body;
b. dilatating an inflatable balloon section of the catheter to dilatate anatomic valves at the anatomic situs within the body;
c. withdrawing the catheter from the dilatated valves at the anatomic situs and positioning a proximal end of a valve stent residing on the catheter;

d. positionally stabilizing the proximal end of the valve stent within the anatomic situs and withdrawing the catheter, inflatable balloon and sheath in a retrograde fashion thereby deploying the valve stent within the anatomic situs.
37. An implantable septal prosthesis, comprising:
a. a tubular stent body member comprising a plurality of spaced struts with interstices intermediate adjacent pairs of struts, the tubular stent body having lumenal and ablumenal surfaces thereof, a central annular opening along a central longitudinal axis of the stent body member, a proximal anchor section, a distal anchor section and an intermediate annular section;
b. a graft member covering at least a portion of at least one of the lumenal and ablumenal surfaces of the stent body member and subtending the central annular opening of the tubular stent body member.
38. The implantable valvular prosthesis according to Claim 38, wherein proximal and the distal anchor sections of the stent body member each further comprise a flange which projects radially outward and away from the central longitudinal axis of the stent body member.
CA2362439A 1999-12-31 2000-12-18 Endoluminal cardiac and venous valve prostheses and methods of manufacture and delivery thereof Expired - Lifetime CA2362439C (en)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US09/477,120 1999-12-31
US09/477,120 US6458153B1 (en) 1999-12-31 1999-12-31 Endoluminal cardiac and venous valve prostheses and methods of manufacture and delivery thereof
PCT/US2000/034591 WO2001049213A2 (en) 1999-12-31 2000-12-18 Endoluminal cardiac and venous valve prostheses and methods of manufacture and delivery thereof

Publications (2)

Publication Number Publication Date
CA2362439A1 true CA2362439A1 (en) 2001-07-12
CA2362439C CA2362439C (en) 2010-06-22

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Family Applications (1)

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CA2362439A Expired - Lifetime CA2362439C (en) 1999-12-31 2000-12-18 Endoluminal cardiac and venous valve prostheses and methods of manufacture and delivery thereof

Country Status (8)

Country Link
US (9) US6458153B1 (en)
EP (2) EP1187582B1 (en)
JP (1) JP2003518984A (en)
AT (1) ATE498373T1 (en)
AU (2) AU783906B2 (en)
CA (1) CA2362439C (en)
DE (1) DE60045632D1 (en)
WO (1) WO2001049213A2 (en)

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US6006134A (en) 1998-04-30 1999-12-21 Medtronic, Inc. Method and device for electronically controlling the beating of a heart using venous electrical stimulation of nerve fibers
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US6652578B2 (en) 2003-11-25
US20010021872A1 (en) 2001-09-13
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US20040106976A1 (en) 2004-06-03
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US9421100B2 (en) 2016-08-23
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US20080125853A1 (en) 2008-05-29

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