CA2364027A1 - Iodine preparation composition - Google Patents

Iodine preparation composition Download PDF

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Publication number
CA2364027A1
CA2364027A1 CA002364027A CA2364027A CA2364027A1 CA 2364027 A1 CA2364027 A1 CA 2364027A1 CA 002364027 A CA002364027 A CA 002364027A CA 2364027 A CA2364027 A CA 2364027A CA 2364027 A1 CA2364027 A1 CA 2364027A1
Authority
CA
Canada
Prior art keywords
iodine
composition
wounds
preparation composition
per
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Granted
Application number
CA002364027A
Other languages
French (fr)
Other versions
CA2364027C (en
Inventor
Dave Parsons
Elizabeth Jacques
Philip Bowler
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Convatec Technologies Inc
Original Assignee
Individual
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Individual filed Critical Individual
Publication of CA2364027A1 publication Critical patent/CA2364027A1/en
Application granted granted Critical
Publication of CA2364027C publication Critical patent/CA2364027C/en
Anticipated expiration legal-status Critical
Expired - Lifetime legal-status Critical Current

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
    • A61L15/00—Chemical aspects of, or use of materials for, bandages, dressings or absorbent pads
    • A61L15/16—Bandages, dressings or absorbent pads for physiological fluids such as urine or blood, e.g. sanitary towels, tampons
    • A61L15/42—Use of materials characterised by their function or physical properties
    • A61L15/44—Medicaments
    • A—HUMAN NECESSITIES
    • A01—AGRICULTURE; FORESTRY; ANIMAL HUSBANDRY; HUNTING; TRAPPING; FISHING
    • A01N—PRESERVATION OF BODIES OF HUMANS OR ANIMALS OR PLANTS OR PARTS THEREOF; BIOCIDES, e.g. AS DISINFECTANTS, AS PESTICIDES OR AS HERBICIDES; PEST REPELLANTS OR ATTRACTANTS; PLANT GROWTH REGULATORS
    • A01N59/00—Biocides, pest repellants or attractants, or plant growth regulators containing elements or inorganic compounds
    • A01N59/12—Iodine, e.g. iodophors; Compounds thereof
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P17/00—Drugs for dermatological disorders
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P17/00—Drugs for dermatological disorders
    • A61P17/02—Drugs for dermatological disorders for treating wounds, ulcers, burns, scars, keloids, or the like
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
    • A61L2300/00—Biologically active materials used in bandages, wound dressings, absorbent pads or medical devices
    • A61L2300/10—Biologically active materials used in bandages, wound dressings, absorbent pads or medical devices containing or releasing inorganic materials
    • A61L2300/106—Halogens or compounds thereof, e.g. iodine, chlorite
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
    • A61L2300/00—Biologically active materials used in bandages, wound dressings, absorbent pads or medical devices
    • A61L2300/40—Biologically active materials used in bandages, wound dressings, absorbent pads or medical devices characterised by a specific therapeutic activity or mode of action
    • A61L2300/404—Biocides, antimicrobial agents, antiseptic agents
    • Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10—TECHNICAL SUBJECTS COVERED BY FORMER USPC
    • Y10S—TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10S424/00—Drug, bio-affecting and body treating compositions
    • Y10S424/13—Burn treatment

Abstract

An iodine preparation composition suitable for use on wounds comprising an iodide source, an oxidant and a buffer characterised in that the iodide is held separately from the oxidant until the point of use, and that the buffer is capable of maintaining the pH of the composition at between pH 4.5 and pH 6 so that iodine is generated at a physiologically acceptable dose rate.</SDOA B>

Claims (8)

1. An iodine preparation composition suitable for use on wounds composing an iodine source, and oxidant sad a buffer characterised in that the iodine is held separately from the oxidant until the point of use, and that the buffer 19 capable of maintaining the pH of the composition at between pH 4.5 and pH 6 so that iodine is generated at a physiologically acceptable dose and rate.
2. An iodine preparation composition as claimed in claim 1 characterised in that the composition is capable of generating from 5µg of iodine per g of composition per hour to 1500µg of iodine per g of composition per hour, preferably 100µg of iodise per g of composition per hour.
3. An iodine composition as claimed in claim 2 formulated to generate the said levels of iodine over a period of three days.
4. An iodine composition according to say preceding claim wherein the pH of the composition is maintained between 5.4 and 5.8.
5. An iodine composition according to any preceding claim which includes from 0.2%
to 2% by weight of iodine.
6. The use of an iodine preparation composition according to any preceding claim for the manufacture of a medicament for use on wounds.
7. Use of an iodine preparation composition according to any preceding claim for the dent of wounds.
8. Use according to claim 6 or 7 for the treatment of sepsis in wounds.
CA2364027A 1999-03-12 2000-03-13 Iodine preparation composition Expired - Lifetime CA2364027C (en)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
GB9905663.2 1999-03-12
GBGB9905663.2A GB9905663D0 (en) 1999-03-12 1999-03-12 Iodine preparation composition
PCT/EP2000/002194 WO2000054593A1 (en) 1999-03-12 2000-03-13 Iodine preparation compositon

Publications (2)

Publication Number Publication Date
CA2364027A1 true CA2364027A1 (en) 2000-09-21
CA2364027C CA2364027C (en) 2011-09-06

Family

ID=10849464

Family Applications (1)

Application Number Title Priority Date Filing Date
CA2364027A Expired - Lifetime CA2364027C (en) 1999-03-12 2000-03-13 Iodine preparation composition

Country Status (12)

Country Link
US (1) US7014871B1 (en)
EP (1) EP1158859B1 (en)
JP (1) JP2002539140A (en)
AT (1) ATE254851T1 (en)
AU (1) AU766031B2 (en)
BR (1) BR0008952A (en)
CA (1) CA2364027C (en)
DE (1) DE60006788T2 (en)
ES (1) ES2209862T3 (en)
GB (1) GB9905663D0 (en)
NZ (1) NZ513991A (en)
WO (1) WO2000054593A1 (en)

Families Citing this family (11)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US6838050B1 (en) 1999-06-04 2005-01-04 Oxibio, Inc. Methods and devices for providing anti-infective activity to a medical device
US6592890B1 (en) 1999-10-20 2003-07-15 Oxibio, Inc. Conveyance of anti-infective activity to wound dressings
MXPA04005219A (en) * 2001-11-29 2005-06-20 Greystone Medical Group Inc Treatment of wounds and compositions employed.
GB0525504D0 (en) * 2005-12-14 2006-01-25 Bristol Myers Squibb Co Antimicrobial composition
US8303994B2 (en) * 2006-06-22 2012-11-06 Jack Howard Kessler Method for the eradication of pathogens including S. aureus and antibiotic resistant microbes from the upper respiratory tract of mammals and for inhibiting the activation of immune cells
GB201020236D0 (en) 2010-11-30 2011-01-12 Convatec Technologies Inc A composition for detecting biofilms on viable tissues
CZ303548B6 (en) 2011-01-05 2012-11-28 Contipro Pharma A.S. Iodine-forming health formulation, process of its preparation and bandage containing thereof
US20150354096A1 (en) 2012-12-20 2015-12-10 Convatec Technologies Inc. Processing of chemically modified cellulosic fibres
CA2950721C (en) * 2014-08-08 2020-05-12 Nichi-Iko Pharmaceutical Co.,Ltd. Jelly-like medicinal composition of potassium iodide
US10568770B2 (en) 2015-05-07 2020-02-25 Kci Licensing, Inc. Controlled release iodine structure for use with wound care
WO2016209966A1 (en) 2015-06-22 2016-12-29 Infection Containment Company, LLC Topical antiseptic system

Family Cites Families (7)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4271149A (en) * 1979-09-21 1981-06-02 West Agro-Chemical, Inc. Germicidal iodine compositions with enhanced iodine stability
JPH02276549A (en) 1989-04-17 1990-11-13 Takahashi Shoten:Kk Device for cutting and carrying tofu
US5081106A (en) * 1990-07-16 1992-01-14 The Oregon Health Sciences University Wound dressing protocol utilizing collagen gelatin formed with iodine
US5128136A (en) * 1990-07-16 1992-07-07 The Oregon Health Sciences University Wound healing kit comprised of gelable collagen
GB9306296D0 (en) * 1993-03-26 1993-05-19 Diversey Corp Improved iodophors,production and use thereof
GB9322555D0 (en) 1993-11-02 1993-12-22 Duncan Group Plc Sterilant system
US6939569B1 (en) * 1998-06-19 2005-09-06 Oxibio, Inc. Medical device having anti-infective and contraceptive properties

Also Published As

Publication number Publication date
ATE254851T1 (en) 2003-12-15
JP2002539140A (en) 2002-11-19
EP1158859B1 (en) 2003-11-26
BR0008952A (en) 2002-04-09
GB9905663D0 (en) 1999-05-05
AU4104900A (en) 2000-10-04
AU766031B2 (en) 2003-10-09
EP1158859A1 (en) 2001-12-05
DE60006788T2 (en) 2004-07-29
CA2364027C (en) 2011-09-06
DE60006788D1 (en) 2004-01-08
ES2209862T3 (en) 2004-07-01
WO2000054593A1 (en) 2000-09-21
NZ513991A (en) 2001-09-28
US7014871B1 (en) 2006-03-21

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Legal Events

Date Code Title Description
EEER Examination request
MKEX Expiry

Effective date: 20200313

MKEX Expiry

Effective date: 20200313