CA2369697A1 - Process and composition for enhancing the action of vitamin a on the cellular activity of an individual, and use of vitamin c - Google Patents

Process and composition for enhancing the action of vitamin a on the cellular activity of an individual, and use of vitamin c Download PDF

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Publication number
CA2369697A1
CA2369697A1 CA002369697A CA2369697A CA2369697A1 CA 2369697 A1 CA2369697 A1 CA 2369697A1 CA 002369697 A CA002369697 A CA 002369697A CA 2369697 A CA2369697 A CA 2369697A CA 2369697 A1 CA2369697 A1 CA 2369697A1
Authority
CA
Canada
Prior art keywords
vitamin
composition
microspheres
group
weight
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Granted
Application number
CA002369697A
Other languages
French (fr)
Other versions
CA2369697C (en
Inventor
Roberto Alcantara Martins Zucchetti
Simoni Chitarra Souza
Luciana Villa Nova Silva
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Natura Cosmeticos SA
Original Assignee
Individual
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Individual filed Critical Individual
Publication of CA2369697A1 publication Critical patent/CA2369697A1/en
Application granted granted Critical
Publication of CA2369697C publication Critical patent/CA2369697C/en
Anticipated expiration legal-status Critical
Expired - Fee Related legal-status Critical Current

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61Q—SPECIFIC USE OF COSMETICS OR SIMILAR TOILETRY PREPARATIONS
    • A61Q19/00—Preparations for care of the skin
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K8/00—Cosmetics or similar toiletry preparations
    • A61K8/02—Cosmetics or similar toiletry preparations characterised by special physical form
    • A61K8/0241—Containing particulates characterized by their shape and/or structure
    • A61K8/025—Explicitly spheroidal or spherical shape
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K8/00—Cosmetics or similar toiletry preparations
    • A61K8/18—Cosmetics or similar toiletry preparations characterised by the composition
    • A61K8/30—Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds
    • A61K8/67—Vitamins
    • A61K8/671—Vitamin A; Derivatives thereof, e.g. ester of vitamin A acid, ester of retinol, retinol, retinal
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K8/00—Cosmetics or similar toiletry preparations
    • A61K8/18—Cosmetics or similar toiletry preparations characterised by the composition
    • A61K8/30—Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds
    • A61K8/67—Vitamins
    • A61K8/676—Ascorbic acid, i.e. vitamin C
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P17/00—Drugs for dermatological disorders
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P17/00—Drugs for dermatological disorders
    • A61P17/16—Emollients or protectives, e.g. against radiation
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K2800/00—Properties of cosmetic compositions or active ingredients thereof or formulation aids used therein and process related aspects
    • A61K2800/40—Chemical, physico-chemical or functional or structural properties of particular ingredients
    • A61K2800/56—Compounds, absorbed onto or entrapped into a solid carrier, e.g. encapsulated perfumes, inclusion compounds, sustained release forms
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K2800/00—Properties of cosmetic compositions or active ingredients thereof or formulation aids used therein and process related aspects
    • A61K2800/40—Chemical, physico-chemical or functional or structural properties of particular ingredients
    • A61K2800/59—Mixtures

Abstract

The present invention refers to a process, a composition and the use of Vitamin C for enhancing the action of Vitamin A on the cellular activity of an individual. According to the invention, the association of Vitamin C to Vitamin A will be applied to said individual at a weight ratio ranging from 1:1 to about 10:1.

Claims (6)

1. Composition for enhancing the action of Vitamin A on the cellular activity of an individual, characterized in that it contains a plurality of dispersed microspheres, said plurality of microspheres comprising Vitamin A and an antioxidant preferably Vitamin E, inserted into a first group of microspheres, and Vitamin C inserted into a second group of microspheres.
2. Composition according to claim 1, characterized in that Vitamin C is present at a composition of about 0,02% by weight, and Vitamin A is present at a concentration of about 0,009% to 0,02% by weight, based on the total weight composition.
3. Composition according to claim 2, characterized in that Vitamin C is contained in the second group of microspheres at a concentration of 0,02%.
4. A composition according to claim 3, characterized in that it contains a first group of microspheres containing Vitamin A at an average concentration of about 0,014% by weight, based on the total weight of the composition.
5. A composition according to claim 4, characterized in that it contains a first group of microsheres containing Vitamin A at an average concentration of 0,014% and Vitamin E at an average concentration of 0,0006% by weight, and cosmetic compounds se-lected from the group consisting of skin structures, preferably squalan and sphingolipide complexes, micronutrients of the skin , preferably seaweed extract, sensorial agents, pref erably moisteners such as glycerin and hydroxy prolisilan C, emollients such as buthylene glycol and cethyl lactate end silicones such as cyclometicone, solar protection factors such as Parsol 1789 and Eusolex 6300, emulsifiers, preferably Carbopol 1342 associated to trielanolamin any soybean lecitin thickeners, preferably xanthan gum;
sequestrants, preferably EDTA, antioxidants such as BHT and dl-.alpha.-tocopherol, fragrances, conservants, water and mixtures thereof.
6. A composition according to claim 1 comprising Vitamin C in association with Vitamin A at a weight ration ranging from about 1:1 to about 10:1 of Vitamin C
to Vitamin A.
CA002369697A 1998-09-08 1999-09-03 Process and composition for enhancing the action of vitamin a on the cellular activity of an individual, and use of vitamin c Expired - Fee Related CA2369697C (en)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
BRPI9803936-9 1998-09-08
BR9803936-9A BR9803936A (en) 1998-09-08 1998-09-08 Process and composition to increase the action of vitamin A on an individual's cellular activity and use of vitamin C.
PCT/BR1999/000072 WO2000013659A2 (en) 1998-09-08 1999-09-03 Process and composition for enhancing the action of vitamin a on the cellular activity of an individual, and use of vitamin c

Publications (2)

Publication Number Publication Date
CA2369697A1 true CA2369697A1 (en) 2000-03-16
CA2369697C CA2369697C (en) 2009-12-15

Family

ID=4070610

Family Applications (1)

Application Number Title Priority Date Filing Date
CA002369697A Expired - Fee Related CA2369697C (en) 1998-09-08 1999-09-03 Process and composition for enhancing the action of vitamin a on the cellular activity of an individual, and use of vitamin c

Country Status (9)

Country Link
US (1) US6967217B1 (en)
EP (1) EP1112059A2 (en)
JP (1) JP2002524405A (en)
AR (1) AR023047A1 (en)
BR (1) BR9803936A (en)
CA (1) CA2369697C (en)
CO (1) CO5150198A1 (en)
PE (1) PE20000896A1 (en)
WO (1) WO2000013659A2 (en)

Families Citing this family (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP1318784A1 (en) * 2000-09-11 2003-06-18 Industria E Comércio de Cosméticos Natura Ltda. Composition of vitamin c and/or vitamin a
US20030232091A1 (en) * 2002-06-17 2003-12-18 Adi Shefer Stabilized retinol for cosmetic dermatological, and pharmaceutical compositions, and use thereof
JP2006502127A (en) * 2002-07-24 2006-01-19 ビーエーエスエフ アクチェンゲゼルシャフト Ascorbate suspension and use as an antioxidant
US11576850B1 (en) 2020-01-06 2023-02-14 Platinum Skin Care, Inc. Face peel formulation and method of application

Family Cites Families (17)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JPH0717504B2 (en) * 1985-03-09 1995-03-01 美浜 久春 Composition for preventing and treating thrombosis
FR2591105B1 (en) 1985-12-11 1989-03-24 Moet Hennessy Rech PHARMACEUTICAL COMPOSITION, IN PARTICULAR DERMATOLOGICAL, OR COSMETIC, BASED ON HYDRATED LIPID LAMELLAR PHASES OR LIPOSOMES CONTAINING A RETINOIDE OR A STRUCTURAL ANALOG OF SUCH A RETINOID AS A CAROTENOID.
US4704280A (en) * 1986-12-19 1987-11-03 Bates Harry L Cosmetic lotion
FR2612775B1 (en) 1987-03-25 1991-10-11 Thorel Jean COMPOSITIONS FOR THE PREVENTION AND TREATMENT OF SKIN DEGENERATION
DK0381543T3 (en) * 1989-01-31 1993-10-04 Coletica Use of solutions of atelocollagen and polyholosides, e.g. glucosaminoglycans, for the preparation of microcapsules, microcapsules prepared in this manner, processes for the preparation of such microcapsules and cosmetic or pharmaceutical compositions or food compositions in which they are present
US5395620A (en) * 1989-01-31 1995-03-07 Coletica Biodegradable microcapsules having walls composed of crosslinked atelocollagen and polyholoside
US5230836A (en) 1991-06-20 1993-07-27 Kalamazoo Holdings, Inc. Low micron-sized ascorbic acid particles, especially a suspension thereof in a medium in which they are insoluble, and the use thereof as an antioxidant for mediums in which the particles remain insoluble
GB9223235D0 (en) * 1992-11-05 1992-12-16 Unilever Plc Cosmetic composition
US5720805A (en) * 1993-04-13 1998-02-24 Southwest Research Institute Titanium-tin-oxide nanoparticles, compositions utilizing the same, and the method of forming the same
FR2717686B1 (en) * 1994-03-22 1996-06-28 Fabre Pierre Cosmetique Dermo-cosmetic composition and preparation process.
US5851538A (en) 1995-12-29 1998-12-22 Advanced Polymer Systems, Inc. Retinoid formulations in porous microspheres for reduced irritation and enhanced stability
DE69810874T2 (en) * 1997-05-02 2003-09-25 Cosmoferm Bv STABLE CONCENTRATE FORMULATION OF VITAMIN C
US6194452B1 (en) * 1997-11-07 2001-02-27 Howard Murad Stable pharmaceutical compositions including ascorbic acid and methods of using same
US6015548A (en) 1998-07-10 2000-01-18 Shaklee Corporation High efficiency skin protection formulation with sunscreen agents and antioxidants
WO1999033439A1 (en) * 1997-12-24 1999-07-08 Shaklee Corporation Composition with high efficiency skin protection from damaging effects of ultraviolet light
US5891470A (en) 1998-04-17 1999-04-06 Advanced Polymer Systems, Inc. Softgel formulation containing retinol
US6228894B1 (en) * 1998-04-17 2001-05-08 Enhanced Derm Technologies, Inc. Softgel-compatible composition containing retinol

Also Published As

Publication number Publication date
JP2002524405A (en) 2002-08-06
CA2369697C (en) 2009-12-15
BR9803936A (en) 2000-04-04
WO2000013659A3 (en) 2000-07-27
CO5150198A1 (en) 2002-04-29
WO2000013659A2 (en) 2000-03-16
US6967217B1 (en) 2005-11-22
AR023047A1 (en) 2002-09-04
PE20000896A1 (en) 2000-11-08
EP1112059A2 (en) 2001-07-04

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Effective date: 20170905