CA2386110A1 - Intranasal delivery system - Google Patents

Intranasal delivery system Download PDF

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Publication number
CA2386110A1
CA2386110A1 CA002386110A CA2386110A CA2386110A1 CA 2386110 A1 CA2386110 A1 CA 2386110A1 CA 002386110 A CA002386110 A CA 002386110A CA 2386110 A CA2386110 A CA 2386110A CA 2386110 A1 CA2386110 A1 CA 2386110A1
Authority
CA
Canada
Prior art keywords
dose
delivery
administrator
aperture
stream
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Granted
Application number
CA002386110A
Other languages
French (fr)
Other versions
CA2386110C (en
Inventor
Steven J. Penner
Randal W. Sebring
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Heska Corp
Original Assignee
Individual
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Individual filed Critical Individual
Priority to CA002541848A priority Critical patent/CA2541848C/en
Publication of CA2386110A1 publication Critical patent/CA2386110A1/en
Application granted granted Critical
Publication of CA2386110C publication Critical patent/CA2386110C/en
Anticipated expiration legal-status Critical
Expired - Lifetime legal-status Critical Current

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M15/00—Inhalators
    • A61M15/0028—Inhalators using prepacked dosages, one for each application, e.g. capsules to be perforated or broken-up
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M15/00—Inhalators
    • A61M15/0065—Inhalators with dosage or measuring devices
    • A61M15/0068—Indicating or counting the number of dispensed doses or of remaining doses
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M15/00—Inhalators
    • A61M15/0065—Inhalators with dosage or measuring devices
    • A61M15/0068—Indicating or counting the number of dispensed doses or of remaining doses
    • A61M15/0081—Locking means
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M2205/00—General characteristics of the apparatus
    • A61M2205/07—General characteristics of the apparatus having air pumping means
    • A61M2205/071—General characteristics of the apparatus having air pumping means hand operated
    • A61M2205/073—Syringe, piston type

Abstract

This invention relates to apparatus and methods of delivering various compositions including medicaments to a variety of targets. The invention includes a dose administrator (1) which may be used for intranasal delivery of compositions or medicaments, such as live virus vaccines, to both humans and animals. An axial collapse prevention element (2) to prevent excessive axial deflection of the dose administrator (1) or a dose-location coordinate indicator (3) to facilitate the delivery of a dose to the desired target location may be coupled to the dose administrator (1). An intranasal probe (4) having a force dissemination contact surface (7) may be responsive to a first end of the dose administrator (1). The dose may be delivered from a conformable dose sequestration element (10) through an aperture which penetrates the dose delivery aperture element (5) and the dose may be caused to stream by coupling a stream delivery element (6) to the dose delivery aperture element (5). The force application element (12) which acts upon the dose may be separated from the dose by a fluid dose propellant (13). While the invention may be used for numerous applications, it specifically addresses the difficulties of delivering cold-adapted live equine influenza viruses intranasally to equids.
CA002386110A 1999-09-29 2000-09-29 Intranasal delivery system Expired - Lifetime CA2386110C (en)

Priority Applications (1)

Application Number Priority Date Filing Date Title
CA002541848A CA2541848C (en) 1999-09-29 2000-09-29 Intranasal delivery system

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US09/408,584 1999-09-29
US09/408,584 US6398774B1 (en) 1999-09-29 1999-09-29 Intranasal delivery system
PCT/US2000/026870 WO2001023018A2 (en) 1999-09-29 2000-09-29 Intranasal delivery system

Related Child Applications (1)

Application Number Title Priority Date Filing Date
CA002541848A Division CA2541848C (en) 1999-09-29 2000-09-29 Intranasal delivery system

Publications (2)

Publication Number Publication Date
CA2386110A1 true CA2386110A1 (en) 2001-04-05
CA2386110C CA2386110C (en) 2006-05-30

Family

ID=23616876

Family Applications (3)

Application Number Title Priority Date Filing Date
CA2640663A Expired - Lifetime CA2640663C (en) 1999-09-29 2000-09-29 Intranasal delivery system
CA002386110A Expired - Lifetime CA2386110C (en) 1999-09-29 2000-09-29 Intranasal delivery system
CA002541848A Expired - Lifetime CA2541848C (en) 1999-09-29 2000-09-29 Intranasal delivery system

Family Applications Before (1)

Application Number Title Priority Date Filing Date
CA2640663A Expired - Lifetime CA2640663C (en) 1999-09-29 2000-09-29 Intranasal delivery system

Family Applications After (1)

Application Number Title Priority Date Filing Date
CA002541848A Expired - Lifetime CA2541848C (en) 1999-09-29 2000-09-29 Intranasal delivery system

Country Status (5)

Country Link
US (2) US6398774B1 (en)
EP (1) EP1225941A4 (en)
AU (4) AU774757B2 (en)
CA (3) CA2640663C (en)
WO (1) WO2001023018A2 (en)

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US20040039352A1 (en) * 2002-06-28 2004-02-26 Paul Bergeson Nasal dosing device
NZ543196A (en) * 2003-05-15 2008-04-30 Univ Oklahoma State DNA vaccine expressing HA1 but not HA2 of equine-2 influenza virus
US7959929B2 (en) 2005-04-21 2011-06-14 University Of Florida Research Foundation, Inc. Materials and methods for respiratory disease control in canines
US11865172B2 (en) 2005-04-21 2024-01-09 University Of Florida Research Foundation, Inc. Materials and methods for respiratory disease control in canines
US8721699B2 (en) * 2005-05-13 2014-05-13 Benechill, Inc. Methods and devices for non-invasive cerebral and systemic cooling
US7824436B2 (en) * 2005-05-13 2010-11-02 Benechill, Inc. Methods and devices for non-invasive cerebral and systemic cooling
US9358150B2 (en) 2005-05-13 2016-06-07 Benechill, Inc. Methods and devices for non-invasive cerebral and systemic cooling alternating liquid mist/gas for induction and gas for maintenance
ES2496315T3 (en) 2005-10-19 2014-09-18 University Of Florida Research Foundation, Incorporated Materials for the control of respiratory disease in canines
WO2008005577A2 (en) * 2006-07-07 2008-01-10 University Of South Florida Compositions of polyphenols and methods of use
US7749191B2 (en) * 2008-03-20 2010-07-06 Beutlich Lp, Pharmaceuticals Device and method for drug delivery
US8015873B2 (en) * 2008-04-25 2011-09-13 Hall David L Detector housing
WO2010054249A1 (en) * 2008-11-07 2010-05-14 Benechill, Inc. Methods of nasopharyngeal cooling for augmenting coronary perfusion pressure
JP5908397B2 (en) 2009-06-09 2016-04-26 デフィルス、インコーポレイテッドＤｅｆｙｒｕｓ， Ｉｎｃ． Interferon administration to prevent or treat pathogen infection
WO2010144797A2 (en) 2009-06-12 2010-12-16 Vaccine Technologies, Incorporated Influenza vaccines with enhanced immunogenicity and uses thereof
WO2010148372A1 (en) 2009-06-19 2010-12-23 Benechill Devices for cooling the nasal cavity
WO2011156594A2 (en) 2010-06-09 2011-12-15 Vaccine Technologies, Incorporated Therapeutic immunization in hiv infected subjects receiving stable antiretroviral treatment
CA2835628C (en) 2011-05-11 2023-01-03 Children's Medical Center Corporation Multiple antigen presenting immunogenic composition, and methods and uses thereof
WO2014124228A1 (en) 2013-02-07 2014-08-14 Children's Medical Center Corporation Protein antigens that provide protection against pneumococcal colonization and/or disease
US11259908B2 (en) * 2016-07-20 2022-03-01 Elanco Us Inc. Animal intranasal administration device, systems, and associated methods

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Also Published As

Publication number Publication date
AU7737600A (en) 2001-04-30
EP1225941A4 (en) 2007-07-11
WO2001023018A3 (en) 2001-12-06
EP1225941A2 (en) 2002-07-31
US7204822B1 (en) 2007-04-17
CA2541848A1 (en) 2001-04-05
CA2640663A1 (en) 2001-04-05
CA2541848C (en) 2008-12-02
AU2008202537A1 (en) 2008-06-26
AU774757B2 (en) 2004-07-08
WO2001023018A2 (en) 2001-04-05
AU2006236004A1 (en) 2006-12-07
US6398774B1 (en) 2002-06-04
AU2004218666B2 (en) 2006-08-31
CA2640663C (en) 2011-09-13
AU2004218666A1 (en) 2004-11-04
AU2006236004B2 (en) 2008-03-13
CA2386110C (en) 2006-05-30

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EEER Examination request
MKEX Expiry

Effective date: 20200929