CA2397789A1 - Novel human kinase protein and polynucleotides encoding the same - Google Patents

Novel human kinase protein and polynucleotides encoding the same Download PDF

Info

Publication number
CA2397789A1
CA2397789A1 CA002397789A CA2397789A CA2397789A1 CA 2397789 A1 CA2397789 A1 CA 2397789A1 CA 002397789 A CA002397789 A CA 002397789A CA 2397789 A CA2397789 A CA 2397789A CA 2397789 A1 CA2397789 A1 CA 2397789A1
Authority
CA
Canada
Prior art keywords
same
novel human
polynucleotides encoding
kinase protein
human kinase
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Granted
Application number
CA002397789A
Other languages
French (fr)
Other versions
CA2397789C (en
Inventor
Gregory Donoho
Erin Hilbun
C. Alexander Turner Jr.
Glenn Friedrich
Brian Zambrowicz
Arthur T. Sands
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Lexicon Pharmaceuticals Inc
Original Assignee
Individual
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Individual filed Critical Individual
Publication of CA2397789A1 publication Critical patent/CA2397789A1/en
Application granted granted Critical
Publication of CA2397789C publication Critical patent/CA2397789C/en
Anticipated expiration legal-status Critical
Expired - Fee Related legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N9/00—Enzymes; Proenzymes; Compositions thereof; Processes for preparing, activating, inhibiting, separating or purifying enzymes
    • C12N9/10—Transferases (2.)
    • C12N9/12—Transferases (2.) transferring phosphorus containing groups, e.g. kinases (2.7)
    • C12N9/1205—Phosphotransferases with an alcohol group as acceptor (2.7.1), e.g. protein kinases
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides

Abstract

Novel human polynucleotide and polypeptide sequences are disclosed that can be used in therapeutic, diagnostic, and pharmacogenomic applications.

Claims (3)

1. An isolated nucleic acid molecule comprising at least 24 contiguous bases of nucleotide sequence first disclosed in SEQ ID NO: 1.
2. An isolated nucleic acid molecule comprising a nucleotide sequence that:

(a) encodes the amino acid sequence shown in SEQ ID
NO: 2; and (b) hybridizes under stringent conditions to the nucleotide sequence of SEQ ID NO: 1 or the complement thereof.
3. An isolated nucleic acid molecule comprising a nucleotide sequence encoding the amino acid sequence shown in SEQ ID NO:2.
CA2397789A 2000-01-18 2001-01-18 Novel human kinase protein and polynucleotides encoding the same Expired - Fee Related CA2397789C (en)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US17669000P 2000-01-18 2000-01-18
US60/176,690 2000-01-18
PCT/US2001/002120 WO2001053493A2 (en) 2000-01-18 2001-01-18 Human kinase protein and polynucleotides encoding the same

Publications (2)

Publication Number Publication Date
CA2397789A1 true CA2397789A1 (en) 2001-07-26
CA2397789C CA2397789C (en) 2010-10-19

Family

ID=22645429

Family Applications (1)

Application Number Title Priority Date Filing Date
CA2397789A Expired - Fee Related CA2397789C (en) 2000-01-18 2001-01-18 Novel human kinase protein and polynucleotides encoding the same

Country Status (6)

Country Link
US (2) US6746861B2 (en)
EP (1) EP1248846A2 (en)
JP (1) JP2004504804A (en)
AU (1) AU784540B2 (en)
CA (1) CA2397789C (en)
WO (1) WO2001053493A2 (en)

Families Citing this family (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US20080050809A1 (en) * 1999-09-28 2008-02-28 Alejandro Abuin Novel human kinases and polynucleotides encoding the same
AU2001241880A1 (en) 2000-02-29 2001-09-12 Millennium Pharmaceuticals, Inc. 2504, 15977, and 14760, novel protein kinase family members and uses therefor
AU2003258095A1 (en) * 2002-08-07 2004-02-25 Exelixis, Inc. MP21S AS MODIFIERS OF THE p21 PATHWAY AND METHODS OF USE

Family Cites Families (25)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4215051A (en) 1979-08-29 1980-07-29 Standard Oil Company (Indiana) Formation, purification and recovery of phthalic anhydride
US4376110A (en) 1980-08-04 1983-03-08 Hybritech, Incorporated Immunometric assays using monoclonal antibodies
DE3301833A1 (en) 1983-01-20 1984-07-26 Gesellschaft für Biotechnologische Forschung mbH (GBF), 3300 Braunschweig METHOD FOR SIMULTANEOUS SYNTHESIS OF SEVERAL OLIGONOCLEOTIDES IN A SOLID PHASE
US4713326A (en) 1983-07-05 1987-12-15 Molecular Diagnostics, Inc. Coupling of nucleic acids to solid support by photochemical methods
US4594595A (en) 1984-04-18 1986-06-10 Sanders Associates, Inc. Circular log-periodic direction-finder array
US4631211A (en) 1985-03-25 1986-12-23 Scripps Clinic & Research Foundation Means for sequential solid phase organic synthesis and methods using the same
US4946778A (en) 1987-09-21 1990-08-07 Genex Corporation Single polypeptide chain binding molecules
US5700637A (en) 1988-05-03 1997-12-23 Isis Innovation Limited Apparatus and method for analyzing polynucleotide sequences and method of generating oligonucleotide arrays
US5424186A (en) 1989-06-07 1995-06-13 Affymax Technologies N.V. Very large scale immobilized polymer synthesis
US5744101A (en) 1989-06-07 1998-04-28 Affymax Technologies N.V. Photolabile nucleoside protecting groups
US5143854A (en) 1989-06-07 1992-09-01 Affymax Technologies N.V. Large scale photolithographic solid phase synthesis of polypeptides and receptor binding screening thereof
US5252743A (en) 1989-11-13 1993-10-12 Affymax Technologies N.V. Spatially-addressable immobilization of anti-ligands on surfaces
US6150584A (en) 1990-01-12 2000-11-21 Abgenix, Inc. Human antibodies derived from immunized xenomice
US6075181A (en) 1990-01-12 2000-06-13 Abgenix, Inc. Human antibodies derived from immunized xenomice
US5264618A (en) 1990-04-19 1993-11-23 Vical, Inc. Cationic lipids for intracellular delivery of biologically active molecules
US5877397A (en) 1990-08-29 1999-03-02 Genpharm International Inc. Transgenic non-human animals capable of producing heterologous antibodies of various isotypes
US6060296A (en) * 1991-07-03 2000-05-09 The Salk Institute For Biological Studies Protein kinases
EP0632832A1 (en) * 1993-01-21 1995-01-11 The Salk Institute For Biological Studies Protein kinases
US5605793A (en) 1994-02-17 1997-02-25 Affymax Technologies N.V. Methods for in vitro recombination
US5837458A (en) 1994-02-17 1998-11-17 Maxygen, Inc. Methods and compositions for cellular and metabolic engineering
DK0773991T3 (en) 1994-07-15 2004-10-25 Cephalon Inc Active calpain expressed in baculovirus
US5908635A (en) 1994-08-05 1999-06-01 The United States Of America As Represented By The Department Of Health And Human Services Method for the liposomal delivery of nucleic acids
US5556752A (en) 1994-10-24 1996-09-17 Affymetrix, Inc. Surface-bound, unimolecular, double-stranded DNA
US5948767A (en) 1994-12-09 1999-09-07 Genzyme Corporation Cationic amphiphile/DNA complexes
US5817479A (en) * 1996-08-07 1998-10-06 Incyte Pharmaceuticals, Inc. Human kinase homologs

Also Published As

Publication number Publication date
WO2001053493A3 (en) 2002-03-07
US20020038009A1 (en) 2002-03-28
CA2397789C (en) 2010-10-19
AU784540B2 (en) 2006-04-27
AU3106501A (en) 2001-07-31
JP2004504804A (en) 2004-02-19
US20050170364A1 (en) 2005-08-04
EP1248846A2 (en) 2002-10-16
US6746861B2 (en) 2004-06-08
WO2001053493A2 (en) 2001-07-26

Similar Documents

Publication Publication Date Title
CA2263889A1 (en) P-selectin ligand proteins
HUP0004188A2 (en) Novel nucleotide sequence coding for the pox b gene
EP1085089A3 (en) Human cyclic nucleotide phosphodiesterase
NZ505880A (en) IL-18 receptor polypeptides
CA2295999A1 (en) Nik proteins, nucleic acids and methods
AU4778101A (en) Novel polypeptides, and nucleic acids encoding the same
CA2177827A1 (en) Novel apoptosis-modulating proteins, dna encoding the proteins and methods of use thereof
CA2147623A1 (en) Novel p-selectin ligand protein
CA2327266A1 (en) Pesticidal toxins and nucleotide sequences which encode these toxins
WO1998006841A3 (en) Two human nsp-like proteins
CA2163641A1 (en) Multiple sclerosis virus
CA2294566A1 (en) Ikk-.alpha. proteins, nucleic acids and methods
CA2281206A1 (en) Geranyl diphosphate synthase genes
AU6724794A (en) GRB3-3 gene, its variants and their uses
WO1995030001A3 (en) Novel p-selectin ligand protein
GB0020331D0 (en) Enzyme
WO2004029202A3 (en) Microbial trypsin variants having chymotrypsin activity and nucleic acids encoding same
CA2397789A1 (en) Novel human kinase protein and polynucleotides encoding the same
AU5776799A (en) Modified hcv peptide vaccines
CA2448347A1 (en) Novel human hydroxylases and polynucleotides encoding the same
RU97103147A (en) DNA SEQUENCES ENCODING HUMAN PROTEINS TX AND TU RELATED TO CONVERTERING INTERLEUKIN-1-BETA ENZYME
WO2001032706A3 (en) Novel human transporter proteins and polynucleotides encoding the same
CA2311646A1 (en) Tsa305 gene
WO1998032849A3 (en) Polynucleotide associated with the bo or bor syndrome, its corresponding polypeptide and diagnostic and therapeutic applications
JP2004500045A5 (en)

Legal Events

Date Code Title Description
EEER Examination request
MKLA Lapsed