CA2411153A1 - Method for preparing a composition - Google Patents

Method for preparing a composition

Info

Publication number
CA2411153A1
CA2411153A1 CA002411153A CA2411153A CA2411153A1 CA 2411153 A1 CA2411153 A1 CA 2411153A1 CA 002411153 A CA002411153 A CA 002411153A CA 2411153 A CA2411153 A CA 2411153A CA 2411153 A1 CA2411153 A1 CA 2411153A1
Authority
CA
Canada
Prior art keywords
compositions
preparing
solution
homogeneous dispersion
relates
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Granted
Application number
CA002411153A
Other languages
French (fr)
Other versions
CA2411153C (en
Inventor
Patrick Busson
Marco Schroeder
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Cheplapharm Arzneimittel GmbH
Original Assignee
Patrick Busson
Marco Schroeder
F. Hoffmann-La Roche Ag
Cheplapharm Arzneimittel Gmbh
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Family has litigation
First worldwide family litigation filed litigation Critical https://patents.darts-ip.com/?family=8169074&utm_source=google_patent&utm_medium=platform_link&utm_campaign=public_patent_search&patent=CA2411153(A1) "Global patent litigation dataset” by Darts-ip is licensed under a Creative Commons Attribution 4.0 International License.
Application filed by Patrick Busson, Marco Schroeder, F. Hoffmann-La Roche Ag, Cheplapharm Arzneimittel Gmbh filed Critical Patrick Busson
Publication of CA2411153A1 publication Critical patent/CA2411153A1/en
Application granted granted Critical
Publication of CA2411153C publication Critical patent/CA2411153C/en
Anticipated expiration legal-status Critical
Expired - Lifetime legal-status Critical Current

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/20—Pills, tablets, discs, rods
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/10—Dispersions; Emulsions
    • A61K9/12—Aerosols; Foams
    • A61K9/122—Foams; Dry foams
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/06—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite
    • A61K47/26—Carbohydrates, e.g. sugar alcohols, amino sugars, nucleic acids, mono-, di- or oligo-saccharides; Derivatives thereof, e.g. polysorbates, sorbitan fatty acid esters or glycyrrhizin
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/30—Macromolecular organic or inorganic compounds, e.g. inorganic polyphosphates
    • A61K47/36—Polysaccharides; Derivatives thereof, e.g. gums, starch, alginate, dextrin, hyaluronic acid, chitosan, inulin, agar or pectin
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/14—Particulate form, e.g. powders, Processes for size reducing of pure drugs or the resulting products, Pure drug nanoparticles
    • A61K9/16—Agglomerates; Granulates; Microbeadlets ; Microspheres; Pellets; Solid products obtained by spray drying, spray freeze drying, spray congealing,(multiple) emulsion solvent evaporation or extraction
    • A61K9/1682—Processes
    • A61K9/1694—Processes resulting in granules or microspheres of the matrix type containing more than 5% of excipient
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/20—Pills, tablets, discs, rods
    • A61K9/2095—Tabletting processes; Dosage units made by direct compression of powders or specially processed granules, by eliminating solvents, by melt-extrusion, by injection molding, by 3D printing
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P3/00—Drugs for disorders of the metabolism
    • A61P3/04—Anorexiants; Antiobesity agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P3/00—Drugs for disorders of the metabolism
    • A61P3/06—Antihyperlipidemics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/12—Antivirals
    • A61P31/14—Antivirals for RNA viruses
    • A61P31/16—Antivirals for RNA viruses for influenza or rhinoviruses
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00

Abstract

The present invention relates to a method for the preparation of compositions, preferably pharmaceutical compositions, in form of expanded, mechanically stable, lamellar, porous, spongue-like or foam structures out of solutions and dispersions. This method comprises the steps of a) preparing a solution or a homogeneous dispersion of a liquid and a compound selected from the group consisting of one or more pharmaceutically active compounds, one or more pharmaceutically suitable excipients, and mixtures thereof, followed by b) the expansion of the solution or the homogeneous dispersion without boiling. The invention also relates to the compositions, their further processing and any corresponding dosage forms obtainable by the above method.
CA002411153A 2000-06-27 2001-06-18 Method for preparing a composition Expired - Lifetime CA2411153C (en)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
EP00113535.9 2000-06-27
EP00113535 2000-06-27
PCT/EP2001/006834 WO2002000201A2 (en) 2000-06-27 2001-06-18 Method for preparing a composition

Publications (2)

Publication Number Publication Date
CA2411153A1 true CA2411153A1 (en) 2002-01-03
CA2411153C CA2411153C (en) 2007-01-30

Family

ID=8169074

Family Applications (1)

Application Number Title Priority Date Filing Date
CA002411153A Expired - Lifetime CA2411153C (en) 2000-06-27 2001-06-18 Method for preparing a composition

Country Status (38)

Country Link
US (3) US6534087B2 (en)
EP (1) EP1296656B1 (en)
JP (2) JP4149803B2 (en)
KR (1) KR100557845B1 (en)
CN (1) CN1236764C (en)
AR (1) AR029278A1 (en)
AT (1) ATE334662T1 (en)
AU (2) AU2001281846B2 (en)
BR (1) BRPI0112014B1 (en)
CA (1) CA2411153C (en)
CY (1) CY1105714T1 (en)
CZ (1) CZ301813B6 (en)
DE (1) DE60121953T2 (en)
DK (1) DK1296656T3 (en)
EC (1) ECSP024401A (en)
EG (1) EG24141A (en)
ES (1) ES2269441T3 (en)
HK (1) HK1058314A1 (en)
HR (1) HRP20021009B1 (en)
HU (1) HU229550B1 (en)
IL (2) IL153282A0 (en)
JO (1) JO2247B1 (en)
MA (1) MA26922A1 (en)
ME (1) ME00672B (en)
MX (1) MXPA02012583A (en)
MY (1) MY129798A (en)
NO (1) NO332181B1 (en)
NZ (1) NZ523024A (en)
PE (1) PE20020101A1 (en)
PL (1) PL203804B1 (en)
PT (1) PT1296656E (en)
RU (1) RU2244542C2 (en)
SI (1) SI1296656T1 (en)
TW (1) TWI278325B (en)
UY (1) UY26799A1 (en)
WO (1) WO2002000201A2 (en)
YU (1) YU96602A (en)
ZA (1) ZA200209649B (en)

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Also Published As

Publication number Publication date
ATE334662T1 (en) 2006-08-15
NZ523024A (en) 2004-08-27
NO332181B1 (en) 2012-07-16
MEP90608A (en) 2011-12-20
JP2004501184A (en) 2004-01-15
AU2001281846B2 (en) 2006-04-27
HU229550B1 (en) 2014-01-28
UY26799A1 (en) 2001-12-28
KR100557845B1 (en) 2006-03-10
MA26922A1 (en) 2004-12-20
CY1105714T1 (en) 2010-12-22
ES2269441T3 (en) 2007-04-01
US20030039614A1 (en) 2003-02-27
JO2247B1 (en) 2004-10-07
US6534087B2 (en) 2003-03-18
AR029278A1 (en) 2003-06-18
PL203804B1 (en) 2009-11-30
PT1296656E (en) 2006-12-29
MXPA02012583A (en) 2003-04-10
WO2002000201A2 (en) 2002-01-03
BRPI0112014B1 (en) 2016-09-13
JP2007302683A (en) 2007-11-22
EP1296656B1 (en) 2006-08-02
RU2244542C2 (en) 2005-01-20
HRP20021009A2 (en) 2004-02-29
DE60121953D1 (en) 2006-09-14
US20020018812A1 (en) 2002-02-14
PE20020101A1 (en) 2002-02-12
HUP0302060A3 (en) 2006-07-28
BR0112014A (en) 2003-05-13
ZA200209649B (en) 2004-03-10
EP1296656A2 (en) 2003-04-02
AU8184601A (en) 2002-01-08
CN1236764C (en) 2006-01-18
ME00672B (en) 2011-12-20
IL153282A0 (en) 2003-07-06
DE60121953T2 (en) 2007-03-08
TWI278325B (en) 2007-04-11
CN1438880A (en) 2003-08-27
SI1296656T1 (en) 2006-12-31
NO20026197D0 (en) 2002-12-23
DK1296656T3 (en) 2006-11-27
HUP0302060A2 (en) 2003-09-29
NO20026197L (en) 2002-12-23
HRP20021009B1 (en) 2011-07-31
MY129798A (en) 2007-04-30
US20060134205A1 (en) 2006-06-22
HK1058314A1 (en) 2004-05-14
ECSP024401A (en) 2003-02-06
JP4149803B2 (en) 2008-09-17
CZ2003212A3 (en) 2003-06-18
IL153282A (en) 2008-03-20
WO2002000201A3 (en) 2002-04-18
CZ301813B6 (en) 2010-06-30
US7074431B2 (en) 2006-07-11
YU96602A (en) 2005-03-15
PL365803A1 (en) 2005-01-10
CA2411153C (en) 2007-01-30
KR20030023880A (en) 2003-03-20
EG24141A (en) 2008-08-06

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