CA2413806A1 - Electrokinetic delivery device - Google Patents

Electrokinetic delivery device Download PDF

Info

Publication number
CA2413806A1
CA2413806A1 CA002413806A CA2413806A CA2413806A1 CA 2413806 A1 CA2413806 A1 CA 2413806A1 CA 002413806 A CA002413806 A CA 002413806A CA 2413806 A CA2413806 A CA 2413806A CA 2413806 A1 CA2413806 A1 CA 2413806A1
Authority
CA
Canada
Prior art keywords
pad
electrode
medicament
contained
applicator
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Granted
Application number
CA002413806A
Other languages
French (fr)
Other versions
CA2413806C (en
Inventor
Julian L. Henley
Kuo Wei Chang
Joseph Potter
Dennis I. Goldberg
Christopher H. Porter
V. Lorenzo Porcelli
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Biophoretic Therapeutic Systems LLC
Original Assignee
Biophoretic Therapeutic Systems, Llc
Julian L. Henley
Kuo Wei Chang
Joseph Potter
Dennis I. Goldberg
Christopher H. Porter
V. Lorenzo Porcelli
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Biophoretic Therapeutic Systems, Llc, Julian L. Henley, Kuo Wei Chang, Joseph Potter, Dennis I. Goldberg, Christopher H. Porter, V. Lorenzo Porcelli filed Critical Biophoretic Therapeutic Systems, Llc
Publication of CA2413806A1 publication Critical patent/CA2413806A1/en
Application granted granted Critical
Publication of CA2413806C publication Critical patent/CA2413806C/en
Anticipated expiration legal-status Critical
Expired - Fee Related legal-status Critical Current

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61N—ELECTROTHERAPY; MAGNETOTHERAPY; RADIATION THERAPY; ULTRASOUND THERAPY
    • A61N1/00—Electrotherapy; Circuits therefor
    • A61N1/02—Details
    • A61N1/04—Electrodes
    • A61N1/0404—Electrodes for external use
    • A61N1/0408—Use-related aspects
    • A61N1/0428—Specially adapted for iontophoresis, e.g. AC, DC or including drug reservoirs
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61N—ELECTROTHERAPY; MAGNETOTHERAPY; RADIATION THERAPY; ULTRASOUND THERAPY
    • A61N1/00—Electrotherapy; Circuits therefor
    • A61N1/18—Applying electric currents by contact electrodes
    • A61N1/20—Applying electric currents by contact electrodes continuous direct currents
    • A61N1/30—Apparatus for iontophoresis, i.e. transfer of media in ionic state by an electromotoric force into the body, or cataphoresis
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61N—ELECTROTHERAPY; MAGNETOTHERAPY; RADIATION THERAPY; ULTRASOUND THERAPY
    • A61N1/00—Electrotherapy; Circuits therefor
    • A61N1/02—Details
    • A61N1/04—Electrodes
    • A61N1/0404—Electrodes for external use
    • A61N1/0408—Use-related aspects
    • A61N1/0428—Specially adapted for iontophoresis, e.g. AC, DC or including drug reservoirs
    • A61N1/0432—Anode and cathode
    • A61N1/0436—Material of the electrode
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61N—ELECTROTHERAPY; MAGNETOTHERAPY; RADIATION THERAPY; ULTRASOUND THERAPY
    • A61N1/00—Electrotherapy; Circuits therefor
    • A61N1/02—Details
    • A61N1/04—Electrodes
    • A61N1/0404—Electrodes for external use
    • A61N1/0408—Use-related aspects
    • A61N1/0428—Specially adapted for iontophoresis, e.g. AC, DC or including drug reservoirs
    • A61N1/0432—Anode and cathode
    • A61N1/044—Shape of the electrode
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61N—ELECTROTHERAPY; MAGNETOTHERAPY; RADIATION THERAPY; ULTRASOUND THERAPY
    • A61N1/00—Electrotherapy; Circuits therefor
    • A61N1/02—Details
    • A61N1/04—Electrodes
    • A61N1/0404—Electrodes for external use
    • A61N1/0408—Use-related aspects
    • A61N1/0428—Specially adapted for iontophoresis, e.g. AC, DC or including drug reservoirs
    • A61N1/0448—Drug reservoir

Abstract

An electrokinetic delivery or diagnostic device (10) for self-administration of a medicament. The device includes a housing (12) containing a power supply (14), a first active electrode (24) and a ground tactile electrode (30). An applicator (40) includes a pad (44) for containing medicament for overlying the first electrode (24) of the device (10). The medicament may be applied by the user to the pad (44), contained within the pad (44) or contained in rupturable capsules (56) within the pad (44), together with a hydrogel if necessary for imparting electrical conductivity. In another form, the applicator (70) is self-contained, having a power supply (74), a first electrode (78) overlying a pad (44a) and a ground electrode (80) from the opposite side of the pad (44a) whereby an individual presses the pad (44a) against the treatment site to complete the electrical circuit and electrokinetically drive the medicament into the treatment site.
CA002413806A 2000-05-31 2001-05-21 Electrokinetic delivery device Expired - Fee Related CA2413806C (en)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US09/584,138 2000-05-31
US09/584,138 US6477410B1 (en) 2000-05-31 2000-05-31 Electrokinetic delivery of medicaments
PCT/US2001/016069 WO2001091853A1 (en) 2000-05-31 2001-05-21 Electrokinetic delivery device

Publications (2)

Publication Number Publication Date
CA2413806A1 true CA2413806A1 (en) 2001-12-06
CA2413806C CA2413806C (en) 2006-09-19

Family

ID=24336071

Family Applications (1)

Application Number Title Priority Date Filing Date
CA002413806A Expired - Fee Related CA2413806C (en) 2000-05-31 2001-05-21 Electrokinetic delivery device

Country Status (11)

Country Link
US (5) US6477410B1 (en)
EP (2) EP2277584A1 (en)
JP (1) JP4199457B2 (en)
CN (1) CN1287877C (en)
AU (5) AU2001274851B2 (en)
BR (1) BR0111288A (en)
CA (1) CA2413806C (en)
HK (1) HK1054338A1 (en)
MX (1) MXPA02011842A (en)
RU (1) RU2268075C2 (en)
WO (1) WO2001091853A1 (en)

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