CA2494030A1 - Method for spectrophotometric blood oxygenation monitoring - Google Patents

Method for spectrophotometric blood oxygenation monitoring Download PDF

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Publication number
CA2494030A1
CA2494030A1 CA002494030A CA2494030A CA2494030A1 CA 2494030 A1 CA2494030 A1 CA 2494030A1 CA 002494030 A CA002494030 A CA 002494030A CA 2494030 A CA2494030 A CA 2494030A CA 2494030 A1 CA2494030 A1 CA 2494030A1
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Prior art keywords
wavelength
light signal
subject
tissue
attenuation
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CA002494030A
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French (fr)
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CA2494030C (en
Inventor
Bo Chen
Paul B. Benni
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CAS Medical Systems Inc
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    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B5/00—Measuring for diagnostic purposes; Identification of persons
    • A61B5/145—Measuring characteristics of blood in vivo, e.g. gas concentration, pH value; Measuring characteristics of body fluids or tissues, e.g. interstitial fluid, cerebral tissue
    • A61B5/1455—Measuring characteristics of blood in vivo, e.g. gas concentration, pH value; Measuring characteristics of body fluids or tissues, e.g. interstitial fluid, cerebral tissue using optical sensors, e.g. spectral photometrical oximeters
    • A61B5/14551—Measuring characteristics of blood in vivo, e.g. gas concentration, pH value; Measuring characteristics of body fluids or tissues, e.g. interstitial fluid, cerebral tissue using optical sensors, e.g. spectral photometrical oximeters for measuring blood gases
    • A61B5/14553—Measuring characteristics of blood in vivo, e.g. gas concentration, pH value; Measuring characteristics of body fluids or tissues, e.g. interstitial fluid, cerebral tissue using optical sensors, e.g. spectral photometrical oximeters for measuring blood gases specially adapted for cerebral tissue

Abstract

A method and apparatus for non-invasively determining the blood oxygen saturation level within a subject's tissue is provided that utilizes a near infrared spectrophotometric (NIBS) sensor capable of transmitting a light signal into the tissue of a subject and sensing the light signal once it has passed through the tissue via transmittance or reflectance. The method includes the steps of: (1) transmitting a light signal into the subject's tissue, wherein the transmitted light signal includes a first wavelength, a second wavelength, and a third wavelength; (2) sensing a first intensity and a second intensity of the light signal, along the first, second, and third wavelengths after the light signal travels through the subject at a first and second predetermined distance; (3) determining an attenuation of the light signal for each of the first, second, and third wavelengths using the sensed first intensity and sensed second intensity of the first, second, and third wavelengths; (4) determining a difference in attenuation of the light signal between the first wavelength and the second wavelength, and between the first wavelength and the third wavelength; and (5) determining the blood oxygen saturation level within the subject's tissue using the difference in attenuation between the first wavelength and the second wavelength, and the difference in attenuation between the first wavelength and the third wavelength.
CA002494030A 2002-07-26 2003-07-24 Method for spectrophotometric blood oxygenation monitoring Expired - Lifetime CA2494030C (en)

Applications Claiming Priority (5)

Application Number Priority Date Filing Date Title
US39893702P 2002-07-26 2002-07-26
US60/398,937 2002-07-26
US40727702P 2002-08-30 2002-08-30
US60/407,277 2002-08-30
PCT/US2003/022999 WO2004010844A2 (en) 2002-07-26 2003-07-24 Method for spectrophotometric blood oxygenation monitoring

Publications (2)

Publication Number Publication Date
CA2494030A1 true CA2494030A1 (en) 2004-02-05
CA2494030C CA2494030C (en) 2009-06-09

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CA002494030A Expired - Lifetime CA2494030C (en) 2002-07-26 2003-07-24 Method for spectrophotometric blood oxygenation monitoring

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US (3) US7072701B2 (en)
EP (1) EP1545298B1 (en)
JP (2) JP4465271B2 (en)
AU (1) AU2003254135B2 (en)
CA (1) CA2494030C (en)
WO (1) WO2004010844A2 (en)

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