CA2518664A1 - Saturated and unsaturated n-alkamides exhibiting taste and flavor enhancement effect in flavor compositions - Google Patents

Abstract

The present invention is directed to novel compounds and a process for augmenting or imparting a flavor enhancement effect or modifying the perception of one or more of the five basic taste qualities sweet, sour, salt , bitter and umami, to a foodstuff, chewing gum, medicinal product, toothpaste, alcoholic beverage, aqueous beverage, snack, sauce or soup comprising the step of adding to a foodstuff, chewing gum, medicinal product, toothpaste, alcoholic beverage, aqueous beverage, snack, sauce or soup a flavor enhancement or modification of basic taste quality augmenting, enhancing or imparting quantity and concentration of at least one N-substituted unsaturated alkyl amide defined according to the structures:

Description

i LA PP.ESENTE PARTIE DE CETTE DE~L~NTJE OLT CE BREVETS
COyIPREND PLUS D'UN TOLYIE.
CECI EST LE T01~IE ~ DE
NOTE: Pour les tomes additionels, veillez contacter 1e Bureau Canadien des Brevets.
~TI1~I~~ A~~IJIC~,TI~i~tS / P~~'EI'~'~'S
TTtIIS SECTION OF THE APPLICATION / P ATEN T CON T Aii~S ivi0~rcE
THAN ONE VOLU1~IE.
THIS IS VOLUO~IE ~ OF
NOTE: For additional voiumes please contact the Canadian Patent Offce.

SATURATED AND UNSATURATED N-ALKAMIDES EXHIBITING TASTE AND
FLAVOR ENHANCEMENT EFFECT IN FLAVOR COMPOSITIONS
FIELD OF THE INVENTION
Saturated and unsaturated N-alkamide compounds having sweet, salt or umami taste and flavor enhancement quality.
BACKGROUND OF THE INVENTION
The term Umami, from the Japanese word to describe savory or meaty, is the term used to describe the unique overall fullness, savory or salivatory taste of food. Materials that exhibit this taste quality generally potentate the intensity of glutamate solutions and this is one important characteristic of umami taste. It is increasingly becoming recognized as the fifth sense of taste, the others being sour, sweet, salt and bitter.
Compounds traditionally described as possessing this character are monosodium glutamate (MSG), protein hydrolysates, some amino acids and certain nucleotides and phosphates.
MSG is the most widely used material as a 'taste enhancer' where it synergizes the perception of 'savory' ingredients, but has also been alleged to cause allergic reaction to a proportion of the population.
Among other chemical compounds, several nucleotides have also been described to exhibit the umami effect including Adenosine 5'-(trihydrogen diphosphate), 5'-Cytidylic acid (5'-CMP) , 5' -Uridylic acid (5' -UMP) , 5' -Adenylic acid (5' -AMP) , 5' -Guanylic acid (5'-GMP), 5'-Inosinic acid (5'-IMP) and the di-sodium salts of 5'-Guanylic acid and 5'-Inosinic acid.

Recent literature cites an extensive range of other organic compounds as taste active components of mixtures shown to give the umami taste effect. These include but are not necessarily limited to: organic acids such as succinic acid, lactic acid, saturated straight chain aliphatic acids of six, eight, fourteen, fifteen, sixteen, and seventeen carbon chain lengths, Z4,Z7, Z10,Z13,Z16,Z19-docosahexaenoic acid, Z5,Z8,Z11,Z14,Z17-eicosapentaenoic acid, Z9,Z12, Z16, Z19-octadecadienoic acid, Z9-octadecenoic acid, glutaric acid, adipic acid, suberic acid, and malonic acid. Amino acids having umami effects reported iri the literature include glutamic acid, aspartic acid, threonine, alanine, valine, histidine, praline, tyrosine, cystine, methionine, pyroglutamic acid, leucine, lycine, and glycine.
Dipeptides possessing umami properties include Val-Glu and Glu-Asp.
Other miscellaneous compounds having umami properties include alpha-amino adipic acid, malic acid, alpha -aminobutyric acid, alpha -aminoisobutyric acid, E2,E4-hexadienal, E2,E4-heptadienal, E2,E4-octadienal, E2,E4-decadienal, Z4-heptenal, E2,Z6-nonadienal, methional, E3,E5-octadien-2-one, 1,6-hexanediamine, tetramethylpyrazine, trimethylpyrazine, cis-6-dodecen-4-olide, glutamate glycoconjugates, fish sauce blended with anchovy paste (U. S.
Patent Application 2003/0142090) and a number of naturally occurring amino-acids.
Additionally, a variety of molecules are known by those skilled in the art to provide salt enhancement, these include but are not limited to Adenosine 5'-(trihydrogen diphosphate), 5'-Cytidylic acid (5'-CMP), 5'-Uridylic acid (5'-UMP), 5'-Adenylic acid (5'-AMP), 5'-Guanylic acid (5'-GMP), 5'-Inosinic acid (5'-IMP) and the di-sodium salts of 5'-Guanylic acid and 5'-Inosinic acid, (+)-(S)-Alapyridaine (chemical name N-(1-Carboxyethyl)-6-hydroxymethyl pyridinium-3-ol), succinic acid, cetylpyridium chloride, bretylium tosylate, various polypeptides, mixtures of calcium salts of ascorbic acid, potassium chloride, calcium chloride, magnesium chloride, arginine ammonium chloride, alpha-amino acids and their corresponding hydrogen chloride, ammonium and sodium salts and a number of natural plant extracts. Uses of these materials are described in various U.S. Patents 4,997,672;
5,288,510; 6,541,050, U.S. Patent Application 2003/0091721 and Eur. Pat. Appl. 2003/1291342.
Additionally, choline chloride has been shown to enhance salt and increase palatability of sodium chloride reduced systems, Physiol Behav. 1994,55(6), 1039-46.
In addition to this work, our work has included the identification of new flavor materials described in US Serial Number 10/919,631 filed on August 17, 2004; US Serial Number 10/861,751 filed on June 4, 2004; and US Serial Number 10/783,652 filed February 20, 2004.
Despite these disclosures there is an ongoing need for new flavor ingredients particularly those that exhibit advantageous properties for flavor enhancement or modulation, or more preferably the lowering of MSG and /or salt levels in foodstuffs.

SiJMMARY OF THE INVENTION
The present invention relates to novel compounds and a process for augmenting or imparting a flavor enhancement effect or modifying the perception of one or more of the five basic taste qualities sweet, sour, salt , bitter and umami, to a foodstuff, chewing gum, medicinal product, toothpaste, alcoholic beverage, aqueous beverage, snack, sauce or soup comprising the step of adding to a foodstuff, chewing gum, medicinal product, toothpaste, alcoholic beverage, aqueous beverage, snack, sauce or soup a flavor enhancement or modification of basic taste quality augmenting, enhancing or imparting quantity and concentration of at least one N-substituted unsaturated alkyl amide defined according to the structures:

E/Z
R6 \ H R2 R6 H R2 where Ri = H or methyl;
R2 is selected from the group consisting of H, Cl-C~ alkyl, alkenyl and methylene:
R3 is selected from the group consisting of H, C1-Ce straight or branched chain alkyl, alkenyl, dienalkyl and phenyl;
or if Rl = H, RZ and R' taken together can represent , ~ , ~ ~ , cyclopropyl, cyclobutyl, cyclopentyl, cyclopentenyl, cyclohexyl, or cyclohexenyl;

or if R1 = Me, R' and R' taken together can represent ~ , or cyclopropyl, R~ is selected from the group consisting of H, methyl or ethyl;
RJ is selected from the group consisting of H, methyl and ethyl;
R6 is selected from the group consisting of H, C1-Co straight or branched chain alkyl, alkenyl, alkyldienyl, acyclic or containing no more than one ring;
except for in the case of structure 1 when if Ry - H or methyl and RS = H or methyl, RE as described above and phenyl.
The above formulae define novel compounds with the proviso that in structure l, if R1=H and Rz=H, then R' can not be H or methyl unless R~=RS=H.
As used herein compounds described in structure 2 will be referred to as ~~cyclopropylic amides".
A second embodiment relates to novel compounds and a process for augmenting or imparting a flavor enhancement effect or modifying the perception of one or more of the five basic taste qualities sweet, sour, salt , bitter and umami, to a foodstuff, chewing gum, medicinal product, toothpaste, alcoholic beverage, aqueous beverage, snack, sauce or soup comprising the step of adding to a foodstuff, chewing gum, medicinal product, toothpaste, alcoholic beverage, aqueous beverage, snack, sauce or soup a flavor enhancement or modification of basic taste quality augmenting, enhancing or imparting quantity and concentration of at least one N-substituted unsaturated alkyl amide defined according to the structure:

~ IZ R~ R1 R6 ~ ~ N ~ R2 R6 N R2 where R~' - H or methyl;
R' is selected from the group consisting of H, C1-C9 alkyl, alkenyl and methylene;
R3 is selected from the group consisting of H; C1-Ce straight or branched chain alkyl, alkenyl, dienalkyl and phenyl;
or if R1 - H, R2 and R' taken together can represent ~ , ~/ , ~ ~ , cyclopropyl, cyclobutyl, cyclopentyl, cyclopentenyl, cyclohexyl, or cyclohexenyl;
or if R1 = Me, R' and RJ taken together can represent -' or cyclopropyl, R~ is selected from the group consisting of C1-CS alkyl, alkenyl; removed methylene RJ is selected from the group consisting of H, methyl or ethyl;
R6 is selected from the group consisting of H, methyl and ethyl;
R' is selected from the group consisting of H, C1-C9 straight or branched chain alkyl, alkenyl, alkyldienyl, acyclic or containing no more than one ring;
except for in the case of structure 3 when if RS = H or methyl and R6 = H or methyl, R' as described above and phenyl.

A third embodiment relates to novel compounds and a process for augmenting or imparting a flavor enhancement effect or modifying the perception of one or more of the five basic taste qualities sweet, sour, salt , bitter and umami, to a foodstuff, chewing gum, medicinal product, toothpaste, alcoholic beverage, aqueous beverage, snack, sauce or soup comprising the step of adding to a foodstuff, chewing gum, medicinal product, toothpaste, alcoholic beverage, aqueous beverage, snack, sauce or soup a flavor enhancement or modification of basic taste quality augmenting, enhancing or imparting quantity and concentration of at least one N-substituted unsaturated alkyl amide defined according to the structure:

R6 N ~ R2 where Ri - H or methyl;
R2 is selected from the group consisting of H, C1-CQ alkyl, alkenyl and methylene;
R' is selected from the group consisting of H, C1-Ce straight or branched chain alkyl, alkenyl, dienalkyl and phenyl;
or if R1 = H, R2 and R3 taken together can represent , ~-' , ~ ~ , cyclopropyl, cyclobutyl, cyclopentyl, cyclopentenyl, cyclohexyl, or cyclohexenyl;
or if R1 = Me, R' and R3 taken together can represent or cyclopropyl, Rq is selected from the group consisting of C1-Cq alkyl;

RS is selected from the group consisting of H, methyl or ethyl;
R6 is selected from the group consisting of H, methyl and ethyl;
R' is selected from the group consisting of H, C1-C9 straight or branched chain alkyl, alkenyl, alkyldienyl, acyclic or containing no more than one ring;
except for in the case of structure 4 when if RS = H or methyl and R6 = H or methyl, R' as described above and phenyl.
In addition to the novel compounds and the use of the compounds to enhance the taste of foodstuffs by the incorporation of the above ingredients and others set forth in this specification in foodstuff and other materials.
DETAILED DESCRIPTION OF THE INVENTION
The formula set forth above describes a general class of novel materials that we have found to enhance the flavor characteristics of food.
In a more preferred embodiment of the invention the amides have the structure set forth in I and 2 with wherein where R1 = H or methyl;
RZ is selected from the group consisting of H, C1-Cq alkyl, alkenyl and methylene;
R~' is selected from the group consisting of H, C1-Ca straight or branched chain alkyl, alkenyl, dienalkyl and phenyl;
or if R1 = H, R2 and R' taken together can represent , cyclopropyl, cyclobutyl, ~ , cyclopentyl, cyclopentenyl, cyclohexyl, or cyclohexenyl;

or if R1 = Me, RZ and R3 taken together can represent , or cyclopropyl, RS is selected from the group consisting of H, methyl or ethyl;
RS is selected from the group consisting of H, methyl and ethyl;
R~ is selected from the group consisting of H, C1-C9 straight or branched chain alkyl, alkenyl, alkyldienyl, acyclic or containing no more than one ring;
except for in the case of structure 1 when if R9 = H or methyl and RS = H or methyl, R6 as described above and phenyl.
The above compounds of the present invention can be used in accordance with the present method in enhancing the salt and umami effects in foods. The above formulae define novel compounds with the proviso that in structure l, if R'=H and R2=H, then R~ can not be H or methyl unless R9=RS=H.
In a highly preferred embodiment of the invention the amides have the structure set forth below:

R6 \/Z N R 1 ' R2 Formula I

where Rl = H or methyl;
R2 is selected from the group consisting of H, Ci-CQ alkyl, alkenyl and methylene;
R3 is selected from the group consisting of H, C1-C6 straight or branched chain alkyl, alkenyl, dienalkyl and phenyl;
or if R1 = H, RZ and R' taken together can represent , ~ , ~ ~ , cyclopropyl, cyclobutyl, cyclopentyl, cyclopentenyl, cyclohexyl, or cyclohexenyl;
or if R1 = Me, R' and R' taken together can represent or cyclopropyl, R9 is selected from the group consisting of H, methyl or ethyl;
RS is selected from the group consisting of H, methyl and ethyl;
R6 is selected from the group consisting of H, C;-Cg straight or branched chain alkyl, alkenyl, alkyldienyl, acyclic or containing no more than one ring;
except for in the case of structure 1 when if R4 = H or methyl and Ry - H or methyl, RE as described above and phenyl.
The above compounds of the present invention can be used in accordance with the present method in enhancing the salt and umami effects in foods. The above formulae define novel compounds with the proviso that in structure l, if R1=H and RZ=H, then R' can not be H or methyl unless R9=RS=H.
As used herein the compounds under structure 1 and formula 1 will be referred to as "alkenylamides".
In the most preferred embodiment of the invention the amides have the structure set forth below:

\ \Z R7 N
H

Formula II
wherein: R" is selected from the group consisting of H, methyl;
R~ is selected from the group consisting of H or methyl, or R' and Ra taken together can represent cyclopropyl, or ;
R~ is selected from the group consisting of H or methyl; and Ri° is selected from the group consisting of H or methyl.
The above compounds of the present invention can be used in accordance with the present method in enhancing the salt and umami effects in foods. The above compounds are also novel with the proviso that in Formula II, if R' - H, then Re can not be H or methyl.
In another preferred embodiment of the invention the amides have the structure set forth below:

R6 1'' ~N ~R2 R6 ~ N RZ

where Rl = H or methyl;
R2 is selected from the group consisting of H, C1-Ca alkyl, alkenyl and methylene;
R3 is selected from the group consisting of H, C1-Ce straight or branched chain alkyl, alkenyl, dienalkyl and phenyl;

or if R' = H, RZ and R' taken together can represent , ~-' , ~ ~ , cyclopropyl, cyclobutyl, cyclopentyl, cyclopentenyl, cyclohexyl, or cyclohexenyl;
or if Rj = Me, R' and R' taken together can represent , or cyclopropyl, R° is selected from the group consisting of C1-C~ alkyl, alkenyl and methylene;
RS is selected from the group consisting of H, methyl or ethyl;
R6 is selected from the group consisting of H, methyl and ethyl;
R' is selected from the group consisting of H, C1-Co straight or branched chain alkyl, alkenyl, alkyldienyl, acyclic or containing no more than one ring;
except for in the case of structure 1 when if R' - H or methyl and R6 = H or methyl, R' as described above and phenyl.
In an additional embodiment of the invention a novel compounds and a process for augmenting or imparting a flavor enhancement effect or modifying the perception of one or more of the five basic taste qualities sweet, sour, salt , bitter and umami, to a foodstuff, chewing gum, medicinal product, toothpaste, alcoholic beverage, aqueous beverage, snack, sauce or soup comprising the step of adding to a foodstuff, chewing gum, medicinal product, toothpaste, alcoholic beverage, aqueous beverage, snack, sauce or soup a flavor enhancement or modification of basic taste quality augmenting, enhancing or imparting quantity and concentration of at least one N-substituted unsaturated alkyl amide defined according to the structure:

R6 N~~
t R3 where R1 = H or methyl;
RZ is selected from the group consisting of H, C1-CQ alkyl, alkenyl and methylene:
R' is selected from the group consisting of H, C1-C~ straight or branched chain alkyl, alkenyl, dienalkyl and phenyl;
or if R1 = H, R' and R' taken together can represent , ~ cyclopropyl, cyclobutyl, ~' cyclopentyl, cyclopentenyl, cyclohexyl, or cyclohexenyl;
or if R1 = Me, R' and R' taken together can represent ~-' , or cyclopropyl, R4 is selected from the group consisting of C1-C9 alkyl:
R' is selected from the group consisting of H, methyl or ethyl;
R6 is selected from the group consisting of H, methyl and ethyl;
R' is selected from the group consisting of H, Cl-C9 straight or branched chain alkyl, alkenyl, alkyldienyl, acyclic or containing no more than one ring;
except for in the case of structure 4 when if RS = H or methyl and R~ = H or methyl, R' as described above and phenyl.
As used herein the most preferred compounds will be referred to hereinafter as dienalkylamides.

As used throughout the application, ~ is understood to represent an alkene terminus as depicted in Rz, R3, R' and Re with an attachment to the alpha carbon of the acid moiety in structures l, 2, 3, 4, 5 and Formulae I and II set forth in the examples.
Our invention specifically relates to the novel compositions according to the Structure 3 above:
R'' R' R' R" R' R° R7 Compound Double bond configuration as per drawing H cyclopropyl CHI H H CH,CHZCH=CHCHzCHz N
H cyclopropyl CH2CH3 H H CH,CHZCH~HCHzCHz ~~--(~;N
H cyclopropyl CH2CH2CH3 H H CH,CHzCH=CHCHzCHz N
H cyclopropyl Isopropyl H H CH,CH2CH~HCHzCHz o~
~~--(~~N
CH, CHzCH~HCHz CHz H cyclopropyl t-butyl H H
N
H cyclopropyl Vinyl H H CH,CHzCH~HCHzCHz ~~--(VAN
H cyclopropyl Allyl H H CH,CHZCH=CHCHzCHz o_; ,, ~--~N
H cyclopropyl CH2 H H CH,CHzCH=CHCHzcHz Cyclo- N
propyl CH3 CHzCH=CHCHz CHz 0~-H cyclopropyl butyl H ~~--(~~H
N
H cyclopropyl Sec-butyl H H CH,CHzCH=CHCHzCHz ~~--(~~N
H -cyclopropyl CH3 H H CH,CHzCH=CHCHzCHz --o R R R R R R7 Double bond configuration as per drawing H cyclopropyl CH3CH2 H H cH,CHzCH=CHCHzCHz ~ N
H cyclopropyl CH3CH2CH2 H H CH,cH2CH=CHCHzCH2 \ N
H cyclopropyl Isopropyl H H CH,cH_cH=CHCHzCHz N
H cyclopropyl t-butyl H H CH,cH2CH=CHCHzCHZ
H cyclopropyl vinyl H H cH,cH,cH=CHCHzcHZ
N
H cyclopropyl allyl H H cH,cHZCH=cHCHzcH2 w w N
H H CH, CHzCH=CHCHs CHi H cyclopropyl CH2 ~ w Cyclo- N
propyl H cyclopropyl butyl H H CH,cHzCH=CHCHzCHz H cyclopropyl Sec-butyl H H cH,CHzCH=CHCHzCH_ o H cyclopropyl CH3 H H GCH w H cyclopropyl CH3CH2 H H CH ~ N
G

H cyclopropyl CH3CH2CH2 H H GCH
~N
I~I\
O
H cyclopropyl Isopropyl H H

R R R R R R R7 Double bond configuration as per drawing H cyclopropyl t-butyl H H GCH
~~N

H cyclopropyl vinyl H H GCH w N
w w H cyclopropyl allyl H H GCH N

H cyclopropyl CH2 H H GCH w N
Cyclo- \
propyl H cyclopropyl butyl H H GCH w N

H cyclopropyl Sec-butyl H H GCH
\ ,N
W
H cyclopropyl CH3 H H GCH
\ o N

H cyclopropy \ o \ N
H cyclopropyl CH3CH2CH2 H H CH
G
H cyclopropyl Isopropyl H H CH
G ~o \ N
H cyclopropyl t-butyl H H GCH
\ o w N

!~ R R R R R R7 Double bond configuration as per drawing H cyclopropyl vinyl H H CH
G °
N
H cyclopropyl allyl H H CH

N
H cyclopropyl CH2 H H CH
Cyclo- °
propyl ~ N
H cyclopropyl butyl H H GCH

N
H cyclopropyl Sec-butyl H H CH

N
O
H cyclopropyl CH3 Me H
~I

H cyclopropyl CH3CH2 Me H
I N
O
H cyclopropyl CH3CH2CH2 Me H
I N
W
O
H cyclopropyl Isopropyl Me H
w H cyclopropyl t-butyl Me H
N
O
H cyclopropyl vinyl Me H ~ I ~ ~ N
y I I

R R R R R R R7 Double bond configuration as per drawing H cyclopropyl allyl Me H ~ I / I ~ N
O

H cyclopropyl CH2 Me H
/ I W N
Cyclo-propyl H cyclopropyl butyl Me H
/ I W N
N
H cyclopropyl Sec-butyl Me H
\
H cyclopropyl CH3 Me H i I I
/ o N
H cyclopropyl CH3CH2 Me H i I I
/ o N
J
H cyclopropyl CH3CH2CH2 Me H i I I
/ o N
H cyclopropyl Isopropyl Me H i I I /

N
H cyclopropyl t-butyl Me H / I I /
\ o N
~/W
H cyclopropyl Vinyl Me H ~ I I /
\ o N
VJ

R R R R R R R7 Compouna Double bond configuration as per drawing H cyclopropyl Allyl Me H i I I

\ 0 \ N
H cyclopropyl CH2 Me H / I \

Cyclo- \ I /
Propyl N

H cyclopropyl Butyl Me H ~ I I
/ o \
\ N
H cyclopropyl Sec-butyl Me H i I I
/ o \ N
O
I \
H cyclopropyl CH3 Me H
\ / I 10 \ o H cyclopropyl CH3CH2 Me H I
/ I \ N
\ \
O
H cyclopropyl CH3CH2CH2 Me H / I
\ \ I \ N l~
O
H cyclopropyl Isopropyl Me H i I , \ N
\ \I 0 ro 1 t-but 1 Me H ~ I II
H cyclop pY y , I \ N
VV\

H cyclopropyl vinyl Me H
U
\ N
\ \ I
O
H cyclopropyl allyl Me H
I / I \ NO
\ 0 R R R R R R R7 Compound Double bond configuration as per drawing H cyclopropyl CH2 Me H
\ I N
Cyclo-propyl H cyclopropyl butyl Me H , °
\ I \I N
H cyclopropyl Sec-butyl Me H
\ ~I N
H cyclopropyl CH3 H Me \ I ~ o N
I
H cyclopropyl CH3CH2 H Me ~ I
w I ~ o N
H cyclopropyl CH3CH2CH2 H IMe / I
\ ~ oII
~N~
H cyclopropyl isopropyl H Me ~ I
\ ~ '~ o \ N
H cyclopropyl t-butyl H Me ~ I I ~ I, o \
\ N
H cyclopropyl vinyl H Me I
\ I ~ o \ N
H cyclopropyl allyl H Me ~ I
\ ~ ~ o \ N

Rl R' R' R" R' R° R7 Compound Double bond configuration as per drawing H cyclopropyl CH2 H Me ~ w Cyclo- ~ ~ I ' o Propyl \ N
H cyclopropyl butyl H Me I

\ N- 1''/
H cyclopropyl Sec-butyl H Me ,,~.
i o \ N-H cyclopropyl CH3 Me H CH,cHzcH=CHCHzCHz ~~--(~~N
H cyclopropyl CH3CH2 Me H cH,CHzCH=CHCHzCHz o,; -,, ~--~N
J
H cyclopropyl CH3CH2CH2 Me H CH,CHzCH=CHCHzCHz N\
H cyclopropyl isopropyl Me H cH,CHzCH=CHCHzcH2 N
H cyclopropyl t-butyl Me H CH,CHzCH=CHCHzcHz N
H cyclopropyl VlIlyl Me H CH3CHzCH=CHCHzCHz N
H cyclopropyl allyl Me H CH,CHzCH=CHCHzCHz N
H cyclopropyl CH2 Me H CH,CHzCH=CHCHzCHz Cyclo- N
propyl H cyclopropyl butyl Me H CH, CHzCH=CHCHz CHz ~~--(~~N
2i R R R R R R R7 Compound Double bond configuration as per drawing H cyclopropyl CH3CH2CH2 H H
\ N
H cyclopropyl isopropyl H H , I I °
\ I N
H cyclopropyl t-butyl H H
\ ~ I N
H cyclopropyl vinyl H H / I ~o , \ N.
O \ I [/~
~_ H cyclopropyl allyl H H
\ N
\ \I
H cyclopropyl CH2 H H / °
Cyclo- ~ \ N
\ ~ \ I
propyl H cyclopropyl butyl H H
\ N
\ i \I
H cyclopropyl Sec-butyl H H , °
\ N
\ \I
H cyclopropyl CH3 H H / \
0 I.
\ o \ N
VV
H cyclopropyl CH3CH2 H H \
\ ~ I '' o \ N
H cyclopropyl CH3CH2CH2 H H
\ ~ I ~ o \ N- Y/

R1 R' R' R" R' R° R7 Compound Double bond configuration as per drawing H cyclopropyl isopropyl H H
f w I ~ o \ N
H cyclopropyl t-butyl H H I
~I ' o H cyclopropyl vinyl H H , \
I
w ~ ~ o N' ~/J
H cyclopropyl allyl H H ~ \
I

\ N' H cyclopropyl CH2 H H , I \
Cyclo- ~ ~ ~ o propyl N
H cyclopropyl butyl H H I
w I ~ o \ N
H cyclopropyl Sec-butyl H H I
o N- Y/
Me Me CH3 H Me (CH3)iC=CHCHzCHz o \ \ N
I
Me Me CH3CH2 H Me (CH,)zC=CHCHzCHz o J
Me Me CH3CH2CH2 H Me (CH3)ZC=CHCHzCH~ o \ \
N

R1 R' R' R" R° R° R7 Compound Double bond configuration as per drawing Me Me isopropyl H Me (CHs)zC=CHCHZCHz N
Me Me t-butyl H Me (CHs)zC=CHCHzCHz Me Me vinyl H Me (CHs)zC=CHCHzCHz o w w N
J
Me Me allyl H Me (CHs)zC=CHCH2CHz w w N
Me Me CH2 H Me (CHs)zC=CHCHzCHz Cyclo- ~ ~ N
propyl Me Me butyl H Me I (CH;)zC=CHCHzCHz w w N
Me Me Sec-butyl H Me (CH3)zC=CHCHzCHz o N
w w Me Me CH3 H Me (CH3)zC:CHCHzCHz w w N
Me Me CH3CH2 H Me (CH3)zC:CHCHzCHz w w Me Me CH3CH2CH2 H Me (CH3)zC:CHCHzCHz ~~
w w N
Me Me isopropyl H Me (CH3)zC:CHCHzCHz w w Me Me t-butyl H Me (CHs)zC:CHCHzCHz R1 R' R' R" R' R° R7 Compound Double bond configuration as per drawing Me Me vinyl H Me (CH3)zC:CHCH2CHz w w N
J
Me Me allyl H Me (CHz)zC:CHCHzCHz ~N
Me Me CH2 H Me (CHs)zC:CHCH2CHz Cyclo- ~ ~ o propyl N
Me Me butyl H Me (CHz)zC:CHCHzCHz 0~' ~N~
Me Me Sec-butyl H Me (CH;)zC:CHCHzCHz w w N
Et H CH3 H Me (CH3)zC=CHCHZCHz o w w N
Et H CH3CH2 H Me (CH3)zC=CHCHzCHz w w N
,/
Et H CH3CH2CH2 H Me (CH3)zC=CHCHZCHz N
Et H isopropyl H Me (CH,)zC=CHCHZCHz w w N
Et H t-butyl H Me (CH3)zC=CHCH2CHz o w w N
Et H vinyl H Me (CH3)zC=CHCHZCHz Et H allyl H Me (CH3)zC=CHCHZCHz N
Et H CH2 H Me (CH3)2C=CHCHzCHz Cyclo- ~ ~ N
propyl R1 Rz Rj R" R' R° R7 Compound Double bond configuration as per drawing Et H butyl H Me (CH~)zC=CHCHzCHz o w w /N
Et H Sec-butyl H Me (CH=)zC=CHCH2CHz w w N
Et H CH3 H Me (CHs)zC=CHCH2CHz N
Et H CH3CH2 H Me (CHz)zC=CHCHzCHz w w N
J
Et H CH3CH2CH2 H Me (CH3)zC=CHCHZCHz N- v Et H isopropyl H Me (CH3)zC=CHCHzCHz N
Et H t-butyl H Me (CH,)zC=CHCHZCHz W w N
Et H vinyl H Me (CH;)zC=CHCHzCHz w w N
Et H allyl H Me (CH3)zC=CHCHZCHz N
Et H CH2 H Me (CH3)zC=CNCHzCHz Cyclo- ~ ~ o propyl N
Et H butyl H Me (CH3)zC=CHCHzCHz w w ~N

R R R3 R' R' R° R7 Compound Double bond configuration as per drawing Et H Sec-butyl H Me (CH3)zC=CHCHZCHZ
w w N
Me ~,T CH3 Me H °
\ / I \ N
O
Me H CH3CH2 Me H
\ \ I \ N
Me H CH3CH2CH2 Me H
\ / I \ N
\

Me H isopropyl Me H I , I \ N

Me H t-butyl Me H
\ / I \ N
O
Me H vinyl Me H i / I \ N

Me H allyl Me H I , I \ N

Me H CH2 Me H 'I
Cyclo- \ / I \ N
propyl \

Me H butyl Me H I / I \ N
Me H sec-butyl Me H
\ \ I \ N
Me H CH3 Me H I
\ I / o \ N-I

R R R R R~ Double bond configuration R
R

as per drawing Me CH3CH2 Me /

w N

Me CH3CH2CH2 H Me H 0 ,o ~/
N

Me isopropyl / I I
H Me H 0 N

Me t-butyl H
H Me 0 N

Me H vinyl Me H
O .o ~/
N

Me H allyl Me H I

w N

MeH CH2 Me H / I I
Cyclo-propyl ~ N~/

Me butyl Me H / I I

w \ N

H Sec-butyl Me H
Me I i o w \ N

R R R3 R R' R R7 Compound Double bond configuration as per drawing Me H CH3 H Me ~ ~ J
\ N' Me H ~ H Me ~
CH3CH2 ~ \

N

Me H CH3CH2CH2 H Me , \ N_ \ \I

Me H isopropyl H Me , \ N

Me H t-butyl H Me o \ w I N

Me H vinyl H Me \

N

Me H allyl H Me \ \ N
WI

Me H CH2 H Me Cyclo- \
propyl Me H ~ H Me , ~ /
butyl \ N
I

Me H Sec-butyl H Me N

Me H CH3 H Me I

\ N

Me H CH3CH2 H Me I w N

R R R R RS R6 R7 Compound Double bond configuration as per dra~~ring Me H CH3CH2CH2 H Me I \
w I /
\ N
Me H Isopropyl H Me I \
wI /
\ N
Me H t-butyl H Me I
\I /
\ N
Me H Vinyl H Me ~ I
\ I /
\ N
Me H Allyl H Me I
\I
\ N
Me H CH2 H Me , w Cyclo- \ I I ~ o Propyl N
Me H Butyl H Me I w \ I ~ o \ N-Me H Sec-butyl H Me I \
\I /
\ N
H H CH3 Me H
\ / I \ N
H H CH3CH2 Me H
\ I /I \ N

R R R R RS R6 R7 Compound Double bond configuration as per drawing H H CH3CH2CH2 Me H
H H Isopropyl Me H , I °
\ N

\ , N
H H t-butyl Me H , o 0 \, O
H H Vinyl Me H ~
\ N' \
/ \ N
H H Allyl Me H / o w \I
H H CH2 Me H
Cyclo- ~ I I \ N
Propyl H H Butyl Me H ~ o \ N
O
H H Sec-butyl Me H I I
H H CH3 Me H ~ ~ I \
\ N
H H CH3CH2 Me H I \

\ N
i g H CH3CH2CH2 Me H ~ I I

\ N- \
H H Isopropyl Me H , I \

\ N' \

R1 R' R' R" R' R R7 Compound Double bond configuration as per drawing H H t-butyl Me H I

\ I /
N

H H Vinyl Me H I

\ I /
N

H H Allyl Me H I
~

N

H H CH2 Me H w Cyclo- \ ~ I ~ o Propyl N

H H Butyl Me H

\ ~ /
\ N

H H Sec-butyl Me H I

\ I /
\ N

H H CH3 H Me /
N
\i y i H H CH3CH2 H Me ~
N- \

H H CH3CH2CH2 H Me o \ N
I

H H Isopropyl H Me , N

H H t-butyl H Me , N-\ / I

W

H H Vinyl H Me /
H H Allyl H Me /
H H CH2 H Me /
Cyclo- \
Propyl H H Butyl H Me H H Sec-butyl H Me ~ /
N
\
H H CHI H Me / I
~ o \ N
H H CH3CH2 H Me / I I
-o ~N~
H H CH3CH2CH2 H Me \ ~ I ~ o \ N
H H Isopropyl H Me / I I
\ o N
H H t-butyl H Me \ ~ I i o w N
H H Vinyl H Me / I I

N
Compound Double bond configuration as per drawing I

~ I ~ N
O
\ N

~I

R R R R R R R7 Compound Double bond configuration as per drawing H H Allyl H Me I

w N

H H CH2 H Me Cyclo- ~ ~ ~ o Propyl ~ N
i b H H Butyl H Me N
H H Sec-butyl H Me \ N
H H CH3 M2 H CH,CHzCH=CHCHzCHz N
H H CH3CH2 Me H CH,CHzCH=CHCHzCHz °
N
H H CH.iCH2CHZ Me H CH,CHzCH=CHCHzCHz N
I SOpropyl Me H CH, CHzCH=CHCHz CHz °
H H t-butyl Me H CH,CHzCH=CHCHzCHz o, --N
H H Vinyl Me H CH,CHzCH=CHCHzCHz N
H H Al l y1 Me H cH, CHZCH=CHCHz CHz N
H H CH2 Me H cH, CHzCH=CHCHz CHz Cyclo- N
Propyl R R6 R7 C:ompouna Double bond configuration as per drawing Me H CH, CHZCH=CHCHz CHz N
tyl Me H CH,CH2CH=CHCHzCHz O
N
Me H CH, CHzCH=CHCHz CHz O
N
~2 Me H CH, CHZCH=CHCHz CHz O
N
:CH2 M2 H CH, CHzCH=CHCHz CHz p w N
~pyl M2 H CH, CHzCH=CHCHz CHz p N
tyl Me H CH, CHzCH=CHCHz CHz p N
y1 Me H CH, CHzCH=CHCHz CHz p N-y 1 Me H CH, CHzCH=CHCHz CHz ~ O
N
Me H CH, CHzCH~HCHz CHz O

pyl :y1 Me H CHs CHzCH=CHCHz CHz O
N
butyl Me H CH,CHzCH=CHCHzCHz O
N
O
H3 H H CH w ~I

R1 R' R' R" R° R° R7 Compound Double bond configuration as per drawing Me H CH3CH2 H H GCH
~N
o Me H CH3CH2CH2 H H ~ GCH
~N
Me H Isopropyl H H GCH
\ ~N
Me H t-butyl H H GCH °II
~N~
O
Me H Vinyl H H GCH
~N
\ _ Me H Allyl H H \
\ G"
GCH ~ ~.
Me H CH2 H H CH II
Cyclo_ ~ ~ N
Propyl Me H Butyl H H °
\ G~,"
G~H ~ NG
Me H Sec-butyl H H GCH
\ ~N
Me H CH3 H H GCH
\ N
Me H CH3CH2 H H GCH
W N
Me H CH3CH2CH2 H H GH
W N

R R R7 Compouna Double bond configuration as per drawing H H CH

N
H H CH

N
H H GCH
\ oII
N
H H CH

~N~
H H CH
G ~~
\ N
H H CH

\ N
L H H ~CH
I
\ o \ N
O
H H CH w ~N
O
H H GCH w \

2 H H GCH ~~ w~
N

R1 Rj R' R" R' R° R7 Compound Double bond configuration as per drawing H H Isopropyl H H ~CH
~N
\ O
H H t-butyl ~ H H GCH
~N
H H Vinyl H H GCH
\
H H Allyl H H ~CH
w H H CH2 H H CH ~~
Cyclo- \ N
Propyl H H Butyl H H CH
\ N
H H Sec-butyl H H GCH
~,~~NJ~
H H CH3 H H GCH \
\ N
H H CH3CH2 H I H ~CH \
w \ N
H H CH3CH2CH2 H H GCH \
\ N
H H Isopropyl H H /\CH \
~ w~J, \ N

R R R R R R R7 Compound Double bond configuration as per drawing H H t-butyl H H GCH \
\ o \ N
H H Vinyl H H CH
G
\ N
H H Allyl H H CH \

\ N
H H CH2 H H CH \
cyclo- ~ G o propyl \ N
H H Butyl H H GCH \
\ o \ N
H H Sec-butyl H H CH

\ N~

Me Me CH3 H H CH
\ N
O
Me Me CH3CH2 H H GCH
\

Me Me CH3CH2CH2 H H GCH
~N
I~I\
Me Me Isopropyl H H CH
\ N
\
O
Me Me t-butyl H H GCH
\ N

R R R R R R R7 Compound Double bond configuration as per drawing Me Me Vinyl H I H GCH
\

Me Me Allyl ~ H I H ~CH
N~
\
°
Me Me CH2 H H GCH
Cyclo- \ N
Propyl c Me Me Butyl H ~ H I GCH
N
Me Me Sec-butyl H H CH
~N
I
Me Me CH3 H H GCH
N
Me Me CH3CH2 H H GCH
Me Me CH3CH2CH2 H H CH II
N
Me Me Isopropyl H H GCH ~ \ N
Me Me t-butyl H H GCH
Me Me Vinyl H H CH ~ °
G ,;
J
Me Me Allyl H H CH ~ °II
\ N
Me Me CH2 H H CH ~ o Cyclo- \ N
G
Propyl Rl R' R' R" R' R° R7 Compound Double bond configuration as per drawing Me Me Butyl H H ~CH
JJ
\ N
Me Me Sec-butyl H H ~CH
[~, \ N
Me H Et CH3 H Me (CH3)zC=CHCHzCHz o N
Me H Et CH3CH2 H Me (CHz)zC=CHCHzCHz o /N
Me H Et CH3CH2CH2 H Me (CH;)zC=CHCHzCHz ~N~
Me H Et Isopropyl H Me (CH;)zC=CHCHzCHz J o w w Me H Et t-butyl H Me (CHs)zC=CHCHzCHz o w w N
Me H Et Vinyl H Me (CH,)zC=CHCHzCHz o N
J
Me H Et Allyl H Me (CH,)ZC=CHCHZCH2 0 N
Me H Et CH2 H Me (CHz)zC=CHCHzCHz o Cyclo- ~ ~ N
Propyl Me H Et Butyl H Me (CH,)zC=CHCHZCHz o ,,-N
w w Me H Et Sec-butyl H Me (CH3)zC=CHCHzCHz o w w N
Me H Et CH3 H Me (CH3)zC=CHCHZCH2 N' Y

Rl R' R' R" R' R° R7 Compound Double bond configuration as per drawing Me H Et CH3CH2 H Me (CHz)zC=CHCHzCHz O
~N~
Me H Et CH3CH2CH2 H Me (CH;)zC=CHCHZCH \~
w N
Me H Et Isopropyl H Me (CH3)ZC=CHCH2CH2 w w N
Me H Et t-butyl H Me (CHz)2C=CHCH~CH2 ' oI, ~N~
Me H Et Vinyl H Me (CH~)zC=CHCH~CHZ
N
J
Me H Et Allyl H Me (CH3)zC=CHCH~CHz w w Me H Et CH2 H Me (CH3)ZC=CHCHZCHZ
Cyclo- ~ ~ o propyl Me H Et butyl H Me (CH3)zC=CHCHzCH2 w ~N~
Me H Et Sec-butyl H Me (CH3)zC=CHCHzCH I\2 w w 0I[
N
H cyclopropyl CH3 H Me (CH3)ZC=CHCH2CH2 N
H cyclopropyl CH3CH2 H Me (CH3)zC=CHCHZCHz o 'N

Ry R' R' R' R' R° R7 Compound Double bond configuration as per drawing H cyclopropyl CH3CH2CH2 H Me (CH3)ZC=CHCHZCH2 - o ~N
H cyclopropyl Isopropyl H Me (CHs)2C=CHCHZCH2 J/ - o w w N
H cyclopropyl t-butyl H Me (CH3)ZC=CHCHZCH2 0 N
H cyclopropyl Vinyl H ~ Me (CH3)2C=CHCHZCH~ o-w w N
J
H cyclopropyl Allyl H Me (CH~)~C=CHCH2CHz o w w N
H cyclopropyl CH2 H Me (CH3)zC=CHCHzCH~ I o Cyclo- ~ ~ N
Propyl H cyclopropyl Butyl H Me (CH~)2C=CHCHzCHz ,,-N
H cyclopropyl Sec-butyl H Me (CH3)zC=CHCHZCH2 0 w N
H cyclopropyl CH3 H Me (CH3)zC=CHCHzCH2 w w N- Y/
~/~
H cyclopropyl CH3CH2 H Me (CHs)aC=CHCH2CH2 CN
H cyclopropyl CH3CH2CH2 H Me (CH3)ZC=CHCHZCHz w w 'N
H cyclopropyl Isopropyl H Me (CHs)zC=CHCHZCHz //J\J\

R R R R4 R5 R6 R7 Compound Double bond configuration as per drawing H cyclopropyl t-butyl H Me (CHs)zC=CHCHzCHZ

N
H cyclopropyl Vinyl H Me (CH3)ZC=CHCHZCH~
w w J
H cyclopropyl Allyl H Me (CH3)zC=CHCHZCH1 w w N
H cyclopropyl CH2 H Me (CHs)zC=CHCHZCH ~/2 Cyclo- ~ ~ o PropYl N
H cyclopropyl butyl H Me (CH,)~C=CHCHZCHZ J
W w ~N~
H cyclopropyl Sec-butyl ~ H Me (CH3)2C=CHCHzCHz w w N
H Me CH3 H Me (CH3)ZC=CHCHzCHZ
N
H Me CH3CH2 H Me (CH;)ZC=CHCHZCH~
w w 'N
H Me CH3CH2CH2 H Me (CHs)zC=CHCHZCH2 ~N
H Me Isopropyl H Me (CH3)zC=CHCHzCHz w w N
H Me t-butyl H Me (CH3)ZC=CHCHzCH2 N
H Me Vinyl H Me (CHs)zC=CHCHZCHZ o w w N
J
H Me Allyl H Me (CH3)zC=CHCHZCH?
w w N

Rl R' R' R" R' R° R7 Compound Double bond configuration as per drawing H Me CH2 H Me (CH3)zC=CHCHzCHz Cyclo- ~ ~ N
Propyl H Me Butyl H Me (CH=)zC=CHCH2CHz o ~N
w w H Me Sec-butyl ' H Me (CHz)zC=CHCHzCHz /~' o N
H Me CH3 H Me (CH,)zC=CHCH2CHz W w N
H Me CH3CH2 H Me (CH3)2C=CHCHZCHz ~ w CN' Y
H Me CH3CH2CH2 H Me (CH3)zC=CHCHZCH Iz w w N- I
H Me Isopropyl H Me (CH,)zC=CHCHZCHz w N- Y
I
H Me t-butyl H Me (CH3)zC=CHCHzCH~
H Me V i ny 1 H Me (CH3)zC=CHCHZCHz ~ w N
J
H Me Allyl H Me (CH,)zC=CHCHZCHz N
H Me CH2 H Me (CH3)zC=CHCHzCHz Cyclo- ~ ~ o propyl N

R Rz Rj R° R' R° R7 Compound Double bond configuration as per drawing H Me butyl H Me (CHs)2C=CHCHzCHz \ \

~N~
H Me Sec-butyl H Me (CH3)zC=CHCHzCHz \ \

N
H ~ CH3 H Me (CHa)zC=CHCHZCH2 0 \ \ N
H ~ CH3CH2 H Me (CHa)zC=CHCHZCH2 0 \ \ N
O
CH3CH2CH2 H Me (CHs)zC=CHCHZCHZ
H ~ I sopropyl H Me (CHs)zC=CHCH2CHz o \ \ N
H ~ t-butyl H Me (CH,)zC=CHCHZCHZ o \ \ N
H ~ Vinyl H Me (CH;)zC=CHCHZCHZ o \ \ N
J
H ~ Allyl H Me (CH~)2C=CHCH2CH~ o \ \ N
I
H ~ CH2 H Me (CH1)aC=CHCHZCH~ o~~
Cyclo- w \ N
Propyl H ~ Butyl H Me (CHs)aC=CHCHZCH2 0 \ \ N
H ~ Sec-butyl H Me (CH3OC=CHCHZCHz o \ \ N
H ~ CH3 H Me (CH3)zC=CHCHZCHZ

N

Rl R' R' R" R' R° R7 Compound Double bond configuration as per drawing H ~ CH.5CH2 H Me (CH,)zC=CHCHZCHz w N
H ~ CH3CH2CH2 H Me (CH3)zC=CHCHZCHz w N
H ~ Isopropyl H Me (CHz)zC=CHCHZCHZ
'~ ~ W
N
H ~ t-butyl H Me (CN;)zC=CHCHZCHz w N- v H ~ Vinyl H Me (CH;)zC=CHCHzCHz w N
J
H ~ Allyl H Me (CHz)zC=CHCHZCH2 w N
H ~ CH2 H Me (CH~)zC=CHCHzCH2 Cyclo- ~ ~ o propyl N
H ~ butyl H Me (CH;)zC=CHCHzCHz w Q(~
N- v H ~ Sec-butyl H Me (CH3)zC=CHCHzCHz w N- v H CH3 H Me (CH3)zC=CHCHZCHz ~ I
N
J
H CH3CH2 H Me (CH3)zC=CHCHzCHz o N

R~ R' R' R" R' R° R7 Compound Double bond configuration as per dravting H CH3CH2CH2 H Me (CH3)zC=CHCHZCHz o N
H Isopropyl H Me (CHs)zC=CHCH2CHz i o N
H t-butyl H Me (CHs)zC=CHCHZCHz I o N
H Vinyl H Me (CH~)zC=CHCHzCHz 0 N-H Allyl H Me (CH3)zC=CHCHZCHz o N
H CH2 H Me (CHa)zC=CHCHZCHz o Cyclo- ~ ~ N
Propyl H Butyl H Me (CH,)zC=CHCHZCHz o N
H Sec-butyl H Me (CH3)zC=CHCHZCHz o N
H CH3 H Me (CHs)zC=CHCHzCHz N v H ~ CH3CH2 H Me (CH3)ZC=CHCHZCH2 w w N
H CH3CH2CH2 H Me (CHg),C=CHCHzCHz N
H I sopropyl H Me (CH3)zC=CHCH2CHz 0'I
N

R' R' R' R" R' R° R7 Compound Double bond configuration as per drawing H t-butyl H Me (CH3)zC=CHCHzCHz 0!I
N' v H Vinyl H Me (CH3)ZC=CHCHzCHz 0)I /
N
J
H Allyl H Me (CH3)zC=CHCHzCHz 0I~
N' v H CH2 H Me (CH~)zC=CHCH2CH~ I
Cyclo- ~ ~ o propyl N
H butyl H Me (CHa)zC=CHCHzCH2 N' v H Sec-butyl H Me (CH;)zC=CHCH2CHz 0~i N
H cyclopropyl CH3 H H CH~(CH2)4CH=CHCH2 CH2 \ \
N
H cyclopropyl CH3CH2 H H CH~(CH2)QCH=CHCHZ CHz \ \
N
H CyClOpropyl CH3CH2CH2 H H CHx(CHz)QCH=CHCHZ CHZ

\ \
N
H cyclopropyl Isopropyl H H CH3(CHz)4CH=CHCHzCH2 \ \
N

5~

R R Rj R~ R' R° R7 Compound Double bond configuration as per drawing H cyclopropyl t-butyl H H CH,(CH2)4CH=CHCHz CH2 N
H cyclopropyl Vinyl H H CH,(CHZ)4CH=CHCHz CH2 w w N
J
H cyclopropyl Allyl H H CH,(CHz)4CH=CHCHZ CH2 N
H cyclopropyl CH2 H H CH,(CHz)4CH=CHCH2 CHz [

Cyclo-Fropyl N
H cyclopropyl Butyl H H CH3(CH2)QCH=CHCH2 CH2 o' N
H cyclopropyl Sec-butyl H H CH3(CHz)4CH=CHCHz CHZ

N
H cyclopropyl CH3 H H CH3(CHZ)QCH=CHCHz CHZ

N
H cyclopropyl CH3CH2 H H CH3(CHz)4CH=CHCHz CH2 N
Sl Et R R R R R R7 Double bond configuration as per drawing H cyclopropyl CH3CH2CH2 H H CHz(CHZ)QCH=CHCHZ CHZ
N 'C
H cyclopropyl Isopropyl H H CH3(CH2)4CH=CHCHzCH~

N
H cyclopropyl t-butyl H H CH~(CH2)4CH=CHCHZ CHz N
V
H cyclopropyl Vinyl H H CHz(CHZ)QCH=CHCH2 CHz N- 'C /
VJ
H cyclopropyl Allyl H H CH=(CHz)4CH=CHCH2 CHZ

N- 'C /
H cyclopropyl CH2 H H CH~(CHz)aCH=CHCH~ CHz Cyclo- ~ ~ ~ o Propyl N
H cyclopropyl Butyl H H CH3(CHz)QCH=CHCHz CHZ
O
N- 'C
H cyclopropyl Sec-butyl H H CH3(CHzj4CH=CHCHz CH2 N

R R R R R R7 Double bond configuration I I I I as ner drawing H cyclopropyl CH3 H Me /~CH
I\

H cyclopropyl CH3CH2 H Me ~H ~ N
w H cyclopropyl CH3CH2CH2 H Me /~CH
/I v N
O
H cyclopropyl Isopropyl H Me /~CH ~ N
I~\

H cyclopropyl t-butyl H Me /~CH ~ N
I\
H cyclopropyl Vinyl H Me CH \ No w H cyclopropyl Allyl H Me /~CH ~ N
I~I\
w H cyclopropyl CH2 H Me //~CH ~ N
Cyclo- \
Propyl H cyclopropyl Butyl H Me /~CH N
I~I\
w o H cyclopropyl Sec-butyl H Me ~CH
/I~/I N
H cyclopropyl CH3 H Me /~CH

N
H cyclopropyl CH3CH2 H Me /~CH

w N

tt R R R R R R7 Double bond configuration as per drawing H cyclopropyl CH3CH2CH2 H Me /~CH
w /N
H cyclopropyl Isopropyl H Me /~CH
I w w N
H cyclopropyl t-butyl H Me ~ /~CH
w N
H cyclopropyl Vinyl H Me /~CH

N
~J
H cyclopropyl Allyl H Me /~CH
w N
H cyclopropyl CH2 H Me /~CH
Cyclo- I~/I
Propyl w H cyclopropyl Butyl H Me /~CH
I

\ N
H cyclopropyl Sec-butyl H Me /~CH

\ N 7/

R R R R R R R7 Compound Double bond configuration as per drawing H cyclopropyl CH3 H Me Me N
H cyclopropyl CH3CH2 H Me Me H cyclopropyl ICH3CH2CH2 H Me Me \ N
H cyclopropyl Isopropyl H Me \ N
H cyclopropyl t-butyl H Me Me \ N
H cyclopropyl Vinyl H Me Me \ N
J
H cyclopropyl Allyl H Me Me \ N
H cyclopropyl CH2 H Me Me o Cyclo- N
Propyl H cyclopropyl Butyl H Me Me \ N
H cyclopropyl Sec-butyl H Me ~ Me N
H cyclopropyl CH3 H H °
CH \
N
H cyclopropyl CH3CH2 H H
CH
N
H cyclopropyl CH3CH2CH2 H H \ CH
\
N
H cyclopropyl Isopropyl H H \ CH
N

Et R R R R R R~ Double bond configuration as per drawing H cyclopropyl t-butyl H H CH
,~~,"~N
O
~-I cyclopropyl Vinyl H H ~ CH \ N
w w H cyclopropyl A11y1 H H CH \ N

H cyclopropyl CH2 H H CH \
Cyclo- ~ \
,~~,"~N
Propyl H cyclopropyl Butyl H H CH \
~~~~~~~~ N
O
H cyclopropyl Sec-butyl H H CH \
,~~~,.~N
H cyclopropyl CH3 IH H CH

\ N
H cyclopropyl CH3CH2 H H CH
w CN
H cyclopropyl CH3CH2CH2 H H
w \ N
H cyclopropyl Isopropyl H H CH
i \ N T/

R R R R R R R7 Compound Double bond configuration as per drawing H cyclopropyl t-butyl H H CH

N
H cyclopropyl Vinyl H H CH

N
J
H cyclopropyl Allyl H H CH

\ N
H cyclopropyl CH2 H H C [/H
Cyclo-Propyl °
\ N- Y/
H cyclopropyl Butyl H H CH

H cyclopropyl Sec-butyl H H CH

\ N V I
H H CH3 H Me /~CH ~°
~/ \ N' \
H H CH3CH2 H Me \ °
\

H H CH3CH2CH2 H Me /~CH
\ N

R R R R RS R6 R7 Compound Double bond configuration as per drawing H H Isopropyl H Me /~~CH ~ N

H H t-butyl H Me /~CH
\ N
H H Vinyl H Me CH
N
J
H H Allyl H Me /~CH
H H CH2 H Me CH o \ -N
Cyclo-Propyl H H Butyl H Me CH ~°
N' \
w H H Sec-butyl H Me CH °
\ N
H H CH3 H Me /~CH

w N
H H CH3CH2 H Me /~CH

N- \
J
H H CH3CH2CH2 H Me /~CH
-~ w N
H H Isopropyl H Me CH

N

R R R R R R R7 Compound Double bond configuration as per drawing H H t-butyl H Me /~CH

\ N
H H Vinyl H Me /~CH
,,// w \ N
J
H H Allyl H Me //~CH
'I~~ w w N
H H CH2 H Me /~CH
Cyclo- ~/ \
Propyl °
\ N
H H Butyl H Me /~CH
O
N
H H Sec-butyl H Me /~CH
\

N

\ N~ I

\ N
~ 1 \ o \ N

R R R R R R7 Double bond configuration as per drawing H H Isopropyl H H CH w N

H H t-butyl H H CH
N

H H Vinyl H H CH w J

H H Allyl H H CH w H H CH2 H H CH w N
Cyclo-Propyl H H Butyl H H CH w N

H H Sec-butyl H H CH ~ w N

i w N
J

i w N
H H Isopropy l H H CH

N

R R R R7 Compound Double bond configuration as per drawing t-butyl H H CH

\ N
Vinyl H H CH
i \ N
J
Allyl H H CH
i \ N

Cyclo-Propyl N II
Butyl H H C ~H

N
Sec-Butyl H H ~CH
i N
CH3 H H CH3 CHzCH=CHCHz CHz N
CH3CH2 H H CH,CHzCH=CHCHzCHz N
CH3CH2CH2 H H CH,CHzCH=CHCHzCHz --~N
Isopropyl H H CH,CHzCH=CHCHzCHz N

R R~ R' R" R' R° R7 Compound Double bond configuration as per drawing Me H t-butyl H H CH, CHZCH~HCHz CHz o N
Me H Vlnyl H H CH3CHZCH~HCHzCHz o N
Me H Allyl H H CH,CHZCH~HCHzCHz N
Me H CH2 H H CH3 CHzCH=CHCHz CHz o Cyclo- N
propyl Me H Butyl H H CHz CHZCH=CHCHz CHz o N
Me H S2C-butyl H H CHI CHzCH=CHCHz CHz o N
Me H CH,3 H H CHz CHZCH~HCHz CHz ~--~N
Me H CH3CH2 H H cH,CHzCH~HCHzCHz o~
N
Me H CH3CH2CH2 H H cH,CH2CH=CHCHzcHz o~
N
Me H Isopropyl H H cH,cHzcH=CHCHzCHz o~
N
Me H t-butyl H H cH, CHzCH=CHCHz CHz o~
Y--'N
Me H V i n y 1 H H CH, CHzCH~HCHz CHz Y--'N

R R R7 Compound Double bond configuration as per drawing Al l y H H CH, CHzCH~HCHz CHz 1 ~--~N

CHG H H CH, CHsCH=CHCHz CHz Cyclo-propyl Butyl H H CH, CH2CH=CHCHz CHz o N

sec-butylH H CH,CHZCH=CHCHzCHz o ~

N

CH 3 H CH, CHzCH=CHCHz CHz H

N

CH3CH2 H H CH, CHzCH=CHCHz CHz o N

CH3CH2CH H H CH,CHzCH=CHCHzCHz o N

IsopropylH H CH,CHzCH=CHCHzCH2 N

t-butyl H H CH, CHzCH=CHCHz CHz ~ I
N

Vlriyl H H CH~CHzCH=CHCHzCHz o N
~) Al l y1 H H CH, CH2CH=CHCHz CHz N

CH2 H H CH3 CHzCH=CHCHz CHz o Cyclo- N

propyl R R6 R7 ~:ompouna Double bond configuration as per drawing y1 H H CH, CHzCH=CHCHz CHz o N
utyl H H CH, CHzCH=CHCHz CHz N
[ J H H CH, CHzCH=CHCHz CHz o N
CHG H H CH,CHzCH=CHCHzCHz o N
~2CH2 H H CH,CHzCH=CHCHzCHz N
rOpyl H H CH, CHzCH~HCHz CHz o N
utyl H H CH,CHzCH=CHCHZCHz o N
nyl. H H CH3 CHzCH=CHCHz CHz o N
y _ l y l H H CH, CH2CH=CHCHz CH2 0 N
~H2 H H CH3 CHzCH=CHCHz CHz o opyl utyl H H CH,CH2CH=CHCHzCHz N

R1 RZ R' R" R' Rb R7 Compound Double bond configuration as per drawing H H Sec-butyl H H cH;CHzCH=CHCHzCHz N

Our invention specifically relates to the novel compositions according to the formula I above:
Rl R' R'' R" R'' R° Compound Double bond configuration as per drawing H H Me (CH~)zC=CHCHZCHz o \ \ /
H
H H Me (CH3)zC=CHCHzCHz ~' N~--/~
H
H H Me (CH,)zC=CHCHZCHz o \ \ N / /
H
H H Me (CH3)zC=CHCHzCHz \ \
N /
H
H H Me (CH,)zC=CHCHzCHz o /
\ \ N /
H
H H Me (CHs)zC=CHCH2CHz /
N /
H
H H H CHI CHZCH=CHCHz CHz \ \ o N / /
H
H H H CHI CHzCH=CHCHz CHz \ /

N /
H
H cyclopropyl H H cH, CHzCH=CHCHz CHz o N
H

Ry R' R' R" R' R° Compound Double bond configuration as per drawing H cyclopropyl H I-i CH,CHZCH=CHCH2CH2 \ w N
H
H cyclopropyl H H ~H o \ N- Y/
\ C,~Y~ [/H
H cyclopropyl H H CH \

\ N
~H
H cyclopropyl Me H ~ o \ ~ ~ \
\ I H
Me H H H Me , o \I
H H H H Me ~ o \ ~ I
H H H H Me ~ I \
\
\ N
H
H H H Me H CHI CHZCH~HCH~ CHZ
N
H
H H I H Me H CH, CHzCH~HCHZ CHZ o \ \ N
H
H ~ H Me H H ~CH
~N
\ H
H H Me H H ~CH \
[\ O
\ N_ v H
H H H H H ~CH
~N
\ H
H H H H H \
~CH
\ o \ N
H
Me Me Me H H ~CH o \ ~H

R' R' R' R" R' R° Compound Double bond configuration as per drawing Me Me Me H H GCH ~ °
w H
Me H Et H Me (CH3)zC=CHCHZCHz °
w w N
H
Me H Et H Me (CHa)zC=CHCHZCHz w w H
Refering to Formula II above, the present invention relates to the novel compositions according to the formula II above:
R R R R Geranyl 2,3-double Compound Bond configuration Cyclopropyl Me Me E °
N
H
Cyclopropyl Me Me Z
w w N- Y/
~/H
Me Me Me Me E °
N
H
Me Me Me Me Z
w w H
Me Me E °
~ N
H
Me Me Z

N_ H
Me Me E
\ N
H
Me Me Z
N
H

These compounds and uses thereof have been found beneficial in augmenting or imparting an olfactory effect taste enhancement or somatosensory effect to a foodstuff, chewing gum, medicinal product, toothpaste, alcoholic beverage, aqueous beverage, snack, sauce or soup particularly providing a (a) umami taste, (b) salt effects, (c) flavor enhancement, and (d) preferred overall flavor profile.
More specifically, examples of the organoleptic properties for the dienalkylamides of our invention are as follows:
Relating to Formula I
R R R R R R Compound Taste profile H cyclopropyl H H cH3CHCH o Moderate Umami, CHCHZ

w w N~ off fish oily " character H cyclopropyl H H cH, o Oily, moderate (CHz)aCH=CHCI-12I umami ~ ~

CHz N~
~/H

H H H Me H cH3CHCH~HCHzo Potent warming at w ~ N~ lOppm H

Relating to Formula II
R R R R Compound Taste profile Cyclopropyl Me Me ~ Salt, MSG, Umami, mouthfeel, lasting sweetness.

Cyclopropyl Me Me Salty, MSG, Umami, o brothy, mouthfeel, sweetness.
H

R R R R Compound Taste profile Me Me Me Me ~ Some salt enhancement, umami and strong MSG
effect, sweet end profile Me Me Me Me ' Salt enhancement, MSG
\ o enhancement, Umami, brothy, sweet end profile Me Me °~~ Moderate umami, salt ~ N~ like, lemon character.
H
Me Me Moderate umami, some saltiness.
N
H
Me Me ~ Clean, weak umami effect ~ N ~ at lOppm H
Me Me ~ Clean, weak umami effect at lOppm Relating to Structure 3 R R R R R R R Compound Taste profile H Cyclopropyl Et H Me (CHs)ZC=CH~Ii Weak salt and CHZCHz \ \ N~ Umami ~V/J

Other novel compounds of the present invention include the following according to Structure 1 above:
R1 R2 R3 R4 R5 R6 Compound Double bond configuration as per drawing H cyclopropyl H CH3(CHz)4CH=CHCHZ

\ \
N

H

H cyclopropyl Me H CH

/~ H
\

R1 RZ R3 R4 R5 R6 Compound Double bond configuration as per drawing H cyclopropyl H Me /~CH

\ N- Y/
[[//H
H cyclopropyl H Me Me \ N
H
H cyclopropyl H Me °
CH H
\
H cyclopropyl H Me -CH ~ o \ N
H
H cyclopropyl H H cH °
\ I H
H cyclopropyl H H
CH
N
H
H H H H Me //~CH °
w \ H
H H H H Me /~CH

N
H
H H H H Me w CH H
w H H H H Me -CH
\ N
H
H H H H H CH
w H
H H H H H CH
i ~ N
H

R1 R2 R3 R4 R5 R6 Compound Double bond configuration as per drawing Me H Me (CH;)ZC=CHa ~ CH2CH2 ~ ~ N r H

Other compounds of the present invention include the following according to Structure 2 above:
R1 R2 R3 R4 R5 R6 Compound H cyclopropyl H Me (CH,)zC=CHCH2CH2 /~~ o N- Y/

[/H

H cyclopropyl H H CH,CHZCH=CHCHzCHz H

H ~ H Me (CH,)ZC=CHCHZCHZ o N- v H

H H H H Me (CH3)zC=CHCHZCHZ

N
H

H H Me H Me (CH3)zC=CHCHzCH2 0 N

H

H Me Me H Me (CH3)zC=CHCH~CHz o N

H

Other compounds of the present invention include the following according to Structure 4 above:

R R R R R5 R6 R7 Compound Double bond configuration.
as per drawing H CyClOprOpyl CH3 H H cH, CHZCH=CHCHz CHz N
H cyclopropyl CH2CH3 H H CH,CHiCH~HCHzCHz ~~---~~~N
H cyclopropyl CH2CH2CH3 H H cH,cH2cH=CHCHzCHz o N
H cyclopropyl Isopropyl H H cH,CHzCH~HCHzCHz o N
H cyclopropyl t-butyl H H cH,CHzCH~HCHzCHz o N
H cyclopropyl Vinyl H H CH, CH2CH~HCHz CHz o N
H cyclopropyl Allyl H H cH,cHZcH=CHCHzCHz o N
H cyclopropyl CH2 H H cH, CHzCH=CHCHz CHz o Cyclo- N
propyl H cyclopropyl butyl H H cH,CHZCH=CHCHzCHz o N
w H cyclopropyl .Sec-butyl H H CH,CH2CH~HCHzCH2 0 N
H cyclopropyl CH3 H H CH,CHZCH~HCHzCHz o N
H cyclopropyl CH3CH2 H H CH,CHzCH~HCHzCHz 0 w N
H cyclopropyl CH3CH2CH2 H H CH,CHzcH=cHCH2CH2 0 H cyclopropyl Isopropyl H H CH,CH2CH=CHCHZCHz w N

R1 R~ R' R" R' R° R7 Compound Double bond configuration as per drawing H cyclopropyl t-butyl H H cH,CH2CH=CHCHZcHz °
N
H cyclopropyl vinyl H H cH,CHzCH=CHCHzCHz °
\
N
H cyclopropyl -allyl H H cH,CHzcH=CHCHzCI-12 °
N
H cyclopropyl .CH2 H H cH,CHzCH~HCHzCHz °
Cyclo- \
propyl N
H cyclopropyl butyl H H cH, CHzCH=CHCH~ cH2 °
N
H cyclopropyl Sec-butyl H H cH,CHZCH~HCHzCHZ °
N
H cyclopropyl CH3 H H °
(~ ,CH
~\v~N
H cyclopropyl CH3CH2 H H ~CH
~N
H cyclopropyl CH3CH2CH2 H H °
GCH
~N
'\
H cyclopropyl Isopropyl H H GCH
H cyclopropyl t-butyl H H ,/\CH
~N
H cyclopropyl vinyl H H GCH
~N
/1 _\
H cyclopropyl allyl H H ~CH
~N
'\

R R Rj R" R' R° R7 Compound Double bond configuration as per drawing H cyclopropyl CH2 H H °
CH
Cyclo-propyl H cyclopropyl butyl H H CH ~° , N- Y/
H cyclopropyl Sec-butyl H H ~CH \/~\/~
~~~~N
H cyclopropyl CH3 H H ~CH \
N
I
H cyclopropyl CH3CH2 H H ~CH \
N
H cyclopropyl CH3CH2CH2 H H ~CH \
w H cyclopropyl Isopropyl H H CH
G ~°, N
H cyclopropyl t-butyl H H ~CH \
N
H cyclopropyl vinyl H H

N
H cyclopropyl allyl H H CH \
G °
N- Y/

R Rz Rj R" R~ R° R7 Compound Double bond configuration as per drawing H cyclopropyl CH2 H H GCH
Cyclo-w propyl N
H cyclopropyl butyl H H ~CH
N
H cyclopropyl Sec-butyl H H GCH
w H cyclopropyl CH3 Me H ~ °
I ~ I I
H cyclopropyl CH3CH2 Me H I , I N
H cyclopropyl CH3CH2CH2 Me H I
H cyclopropyl Isopropyl Me H I , I N
H cyclopropyl t-butyl Me H I I
H cyclopropyl vinyl Me H I
H cyclopropyl allyl Me H
N
H cyclopropyl CH2 Me H ~ °
Cyclo- ~ I ~ I N
propyl R R R R RS R6 R7 Compound Double bond configuration as per drawing H cyclopropyl butyl Me H
\ \ I N
H cyclopropyl Sec-butyl Me H
\ \I N
H cyclopropyl CH3 Me H , I I

\
I
H cyclopropyl CH3CH2 Me H
w i N
J
H cyclopropyl CH3CH2CH2 Me H I
~i \ o N
H cyclopropyl Isopropyl Me H
\ ~ o N
H cyclopropyl t-butyl Me H
\ ~ I ~ o N
H cyclopropyl Vinyl Me H I
\ ~ ~ o N
J
H cyclopropyl Allyl Me H ~ I I \
\ '~ oI' N

R' R' R' R" R' R° R7 Compound Double bond configuration as per drawing H cyclopropyl CH2 Me H ~ \
Cyclo- \ I I ~ o Propyl N
H cyclopropyl Butyl Me H I \
\ I ~ o N
H cyclopropyl Sec-butyl Me H I \
\ I ~ oII
N
H cyclopropyl CH3 H Me , o \ I \ I I
H cyclopropyl CH3CH2 H Me \ I I
H cyclopropyl CH3CH2CH2 H Me o \ I \ I N
H cyclopropyl isopropyl H Me I I
H cyclopropyl t-butyl H Me ~ o \ I \ I N
H cyclopropyl vinyl H Me ,, o \ I \ I
H cyclopropyl allyl H Me I I
H cyclopropyl CH2 H Me ~ o Cyclo- \ I ~ I N
propyl \

Rl R' R' R" R' R° R7 Compound Double bond configuration as per drawing H cyclopropyl butyl H Me \ I I
H cyclopropyl Sec-butyl H Me I I
H cyclopropyl CH3 H Me w I ~ o N- Y/
(/I
H cyclopropyl CH3CH2 H Me w ~ ~ o N
H cyclopropyl CH3CH2CH2 H Me ~ I
w I ~ o N- Y/
H cyclopropyl isopropyl H Me ~ I
w I ~ o N
H cyclopropyl t-butyl H Me I
w I ~ o ~N
H cyclopropyl vinyl H Me ~ I
o L
H cyclopropyl allyl H Me I

N- Y/
H cyclopropyl CH2 H Me Cyclo- ~ ~ I ~ o Propyl N

R R R R° R' R6 R7 Compound Double bond configuration as per drawing H cyclopropyl butyl H Me w I ~ o N- Y/
[/t H cyclopropyl Sec-butyl H Me w I ~ o N- Y/
H cyclopropyl CH3 Me H cH,CHzCH=CHCHzCHz N
H cyclopropyl CH3CH2 Me H cH,cHZCH=CHCHzCHz N~-~(~
H cyclopropyl ~ CH3CH2CH2 Me H CH,CHZCH=CHCHzCHz o~
N
H cyclopropyl isopropyl Me H cH,CHZCH=CHCHZCHz o N
H cyclopropyl t-butyl Me H cH,cHZCH=CHCH2CH2 0 N
H cyclopropyl vinyl Me H CH,CHzCH~HCHzcHZ ~ o_, ~N
H cyclopropyl allyl Me H CH,CHzCH~HCHzCHz ~~-(~~N
H cyclopropyl CH2 Me H cH,CNzCH=CHCHzCHz o Cyclo- N
propyl H cyclopropyl butyl Me H CH,CHZCH~HCHzCHz o" "
~--~N
H cyclopropyl Sec-butyl Me H cH,CH2CH~HCHzCHz ~N

R1 RZ R' R" R' R° R7 Compound Double bond configuration as per drawing H CyClopropyl CH3 Me H CH,CHzCH=CHCHzCHz oII
I V
H cyclopropyl CH3CH2 Me H ~ CH,CHzCH=CHCHZcHz p \ J
H cyclopropyl CH3CH2CH2 Me H CH,CHzCH~HCHzCHz oII
N
H cyclopropyl isopropyl Me H cH,CHzCH=CHCHzCHz o N
H cyclopropyl t-butyl Me H cH,CH2CH=CHCHzCH2 0II
N T/
H cyclopropyl vinyl Me H cH, CH2CH=CHCH2 cH2 0 H cyclopropyl allyl Me H cH,CHzCH~HCHzCHZ p H cyclopropyl CH2 Me H CH,CHzCH=CHCH~CHZ o Cyclo- w propyl H cyclopropyl butyl Me H CH,CHzCH~HCHzCHz ~ O
w N
H cyclopropyl Sec-butyl Me H cH,CHICH~HCHzCH2 0 w N
H cyclopropyl CH3 H H ~
\ I ~ I I
H cyclopropyl CH3CH2 H H
\ ~ I N
so R R R R R R R7 Compound Double bond configuration as per drawing H cyclopropyl CH3CH2CH2 H H - o \ I
C;V~N~/
H cyclopropyl isopropyl H H , o \ I / I N
H cyclopropyl t-butyl H H o I N
H cyclopropyl vinyl H H o / N
I
H cyclopropyl allyl H~ H ~ o \ / I N
H cyclopropyl CH2 IH H ~ o Cyclo- \ I / I N
propyl H cyclopropyl butyl H H o / I N
[/\
H cyclopropyl Sec-butyl H H ~ o \ / I N
H cyclopropyl CH3 H H I I / o ~N~
(/i H cyclopropyl CH3CH2 H H
I
\ I / o N- Y/
H cyclopropyl CH3CH2CH2 H [/H
I
\ I / o N- Y/

Rl R' R' R" R' R° R7 Compound Double bond configuration as per drawing H cyclopropyl isopropyl H H

N- Y/
H cyclopropyl t-butyl H H I

N- Y/
H cyclopropyl vinyl H H
I
w I ~ o N- Y/
~/
H cyclopropyl allyl H H I w N- Y/
H cyclopropyl CH2 H H ~ I w Cyclo- ~ I ~ o propyl N
H cyclopropyl butyl H H I
w I ~ o N
H cyclopropyl Sec-butyl H H
w I ~ o N- Y/
Me Me CH3 H Me (~Ha)z~=CHCH2CH2 N
Me Me CH3CH2 H Me (CHa)2C=CHCH2CH~
N
J
Me Me CH3CH2CH2 H Me (CH3)ZC=CHCHZCH~
N

R1 R' R' R" R'' R° R7 Compound Double bond configuration as per drawing Me Me isopropyl H Me (CH3)ZC=CHCHzCHz o N
Me Me t-butyl H Me ~ (CH;)zC=CHCHZCHz o Me Me vinyl H Me (CH~)ZC=CHCHZCHz J
Me Me allyl H Me (CHx)ZC=CHCHZCHz o Me Me CH2 H Me (CH3)zC=CHCHZCHz Cyclo- ~ N
propyl Me Me butyl H Me (CH;)zC=CHCHZCHz o N
Me Me Sec-butyl H Me (CHs)zC=CHCH2CH2 0 w N
Me Me CH3 H Me (CHs)zC:CHCH2CH2 w N
Me Me CH3CH2 H Me (CHz)2C:CHCHZCHz N
Me Me CH3CH2CH2 H Me (CH3)2C:CHCHzCH2 N
Me Me isopropyl H Me (CH3)2C:CHCHZCHz w N
Me Me t-butyl H Me (CH3)~C:CHCHzCH~
N

R1 R' R' R" R' R° R7 Compound Double bond configuration as per drawing Me Me vinyl H Me (CH3)zC:CHCH2CHz N
J
Me Me a 11 y1 H Me (CH3)zC:CHCHzCHz N
Me Me CH2 H Me (CH3)zC:CHCH2CHz Cyclo- ~~~ o propyl N
Me Me butyl H Me (CH3)zC:CHCH,CHz ~N~
Me Me Sec-butyl H Me (CH3)zC:CHCH2CHz N
H H CH3 H Me (CHs)zC=CHCHZCHz o w N
H H CH3CH2 H Me (CH3)zC=CHCHZCH2 0 N
-/
H H CH3CH2CH2 H Me (CHs)zC=CHCHzCHZ o w N
H H isopropyl H Me (CH,)zC=CHCHZCHz o w N
H H t-butyl H Me (CH3)zC=CHCHzCHz o N
H H vinyl H Me (CH3)zC=CHCH2CHz o w N
H H allyl H Me (CH3)2C=CHCH2CH2 N
H H CH2 H Me (CH3)zC=CHCHZCHz oII
Cyclo- ~ N
propyl Rl R' R' R" R" R° R7 Compound Double bond configuration as per drawing H H butyl H Me (CHs)zC=CHCHZCHz o w N
H H Sec-butyl H Me (CH3)zC=CHCHZCHz o w N
H H CH3 H Me (CH3)zC=CHCHzCHz N v H H CH3CH2 H Me (CH,)zC=CHCHzCHz 0I' N
H H CH3CH2CH2 H Me (CH,)zC=CHCHZCHz ~JI'w 0'I
N
H H isopropyl H Me (CH3)zC=CHCHZCHz N v H H t-butyl H Me (CH3)zC=CHCH2CHz w N
H H vinyl H Me (CH3)zC=CHCH2CHz ~N~
H H allyl H Me (CH3)ZC=CHCH2CH2 N' v H H CH2 H Me (CH3)zC=CHCHzCHz Cyclo- ~~ o propyl N
H H butyl H Me (CH3)zC=CHCH2CHz N

R R R3 R' R' R° R7 Compound Double bond configuration as per drawing H H Sec-butyl H Me (CHz)zC=CHCHzCHz W

N
Me H CH3 Me H
\ I \ I N~
Me H CH3CH2 Me H , °
\ I \ I N~
C~J
Me H CH3CH2CH2 Me H ~
\ I I N~
Me H isopropyl Me H
\ \ I N
Me H t-butyl Me H ~ °
\ \ I N
Me H vinyl Me H o \ I \ I N~
Me H allyl Me H , °
\ \I
O - N
Me H CH2 Me H ~ °II
Cyclo- \ II ~ I N
propyl Me H butyl Me H o \ \ I N
Me H sec-butyl Me H , °
\ I \ I N~
Me H CH3 Me H I
\I
N

R R R3 R R' R~ R7 Compound Double bond configuration as per drawing Me H CH3CH2 Me H I

w N

Me H CH3CH2CH2 Me H I

~N

Me H isopropyl Me H I w I

w I ~ o N

Me H t-butyl Me H I

N

Me H vinyl Me H

N

Me H allyl Me H I w N

Me H CH2 Me I , w Cyclo- Y: ~ I
I

~

propyl N

Me H butyl Me H

i N

Me H Sec-butyl Me H I w w ~N

g7 R R Rj R R' R R7 Compound Double bond configuration as per drawing Me H CH3 H Me ~ o \ I \ I N~

Me H CH3CH2 H Me ~
I /
N~

\ I
\

Me H CH3CH2CH2 H Me ~
N

\ \ I

Me H isopropyl H Me \ I I N~

\

Me H t-butyl H Me o \ I I N~

\

Me H vinyl H Me , \ I N

Me H allyl H Me o \ I I N~

\

Me H CH2 H Me , II
Cyclo- \ I / I N

propyl \

Me H butyl H Me o \ I N

Me H Sec-butyl H Me , \ I I N~

\

Me H CH3 H Me I
\I /

~N

Me H CH3CH2 H Me I \
I

\ /
N

8g R R R R R' Rb R7 Compound Double bond configuration as per drawing Me H CH3CH2CH2 H Me I

N

Me H Isopropyl H Me I

w ~ o N

Me H t-butyl H Me N

Me H Vinyl H Me w ~N

Me H A11y1 H Me N

Me H CH2 H Me I
Cyclo- I ~

o Propyl N

Me H Butyl H Me N

Me H Sec-butyl H Me I

N

H H CH3 Me H , I N
I

H H CH3CH2 Me H ~
N

Rl R' R' R" R' R° R7 Compound Double bond configuration as per drawing H H CH3CH2CH2 Me H , o \ I / I N~
H H Isopropyl Me H o I /I N~
H H t-butyl Me H ~ ou / I N
H H Vinyl Me H ~ o \ /I N
C;
H H Allyl Me H
/ I N
H H CH2 Me H I' Cyclo- \ I / I N
Propyl H H Butyl Me H o I / I N~
H H Sec-butyl Me H , o \ I \ I N.~
H ~ H CH3 Me H I \
H H CH3CH2 Me H I \
I /
N
H H CH3CH2CH2 Me H I \
I /
'N
H H Isopropyl Me H I
\ I /
~N

Double bond configuration as per drawing H H t-butyl Me H / I I /
o N
H H Vinyl Me H / I I /

N
H H Allyl Me H / I I /
O
N
W
H H CH2 Me I H I
/
Cyclo- \
Propyl N
w H H Butyl Me H / I I /
\ o N
H ~ Sec-butyl Me H / I \ I
H / o N
O
H H CH3 H Me / I / N
I I

H H CH3CH2 H Me i I , N
\ w I v O
H H CH3CH2CH2 H Me / I N
OII
H H Isopropyl H Me / I / N
\

H H t-butyl H Me /
/ I N~
\ ~ v R1 R' R' R" R R R7 Compourid Double bond configuration as per drawing H H Vinyl H Me /
N

\ I

H H Allyl H Me /
N

\ I

H H CH2 H Me ~~
Cyclo- \ I / I N

Propyl \

H H Butyl H Me I N-~

\ \ I

H H Sec-butyl H Me /
N

I

H H CH3 H Me I \

\ I /
-N
I

H H CH3CH2 H Me I \

\ I /
!y H H CH3CH2CH2 H Me I

\I /
L]" 'N

H H Isopropyl H Me I \

\i /

H H t-butyl H Me I \

\ I /
~N

H H Vinyl H Me I \

I
~N

R1 R' R' R" R' R° R7 Compound Double bond configuration as per drawing H H Allyl H Me I w w H H I CH2 H Me ~ w Cyclo- ~ I ~ ~~ o Propyl N
b H H Butyl H Me w ~N
H H Sec-butyl H Me ~N
CH, CHzCH=CHCHi CH2 H H CH3 Me H
N
I
H H CH3CH2 -Me H CH,CH2CH=CHCHZCHz N\
H H CH3CH2CH2 Me H CH,CHZCH=CHCHzCHz N
H H Isopropyl Me H CH,CHzCH=CHCHzCHz o N
H H t-butyl Me H CH,CHzCH=CHCHzCHz N
H H Vlriyl Me H CH, CHzCH=CHCHz CHz o N
H H Al l y1 Me H CH, CHzCH=CHCHz CHz N
H H CH2 Me H CH, CHzCH=CHCHz CHz Cyclo- N
Propyl Rl R' R' R" R' R° R7 Compound Double bond configuration as per drawing CHI CHzCH~HCHz CHz H H Butyl Me H
N
H H Sec-butyl Me H cH,CH2CH~HCHzCHz T~N
H H CH3 Me H CH, CHzCH~HCHz CHz C
N
H H CH3CH2 Me H CH,CHzCH~HCH2CHz o'I
N
H H CH3CH2CH2 Me H cH,CHzCH~HCHzCHz o N
CH, CHzCH=CHCHz CHz H H Isopropyl Me H
N
H H t-butyl Me H CH, CHzCH=CHCHz CHz N_ \
H H Vinyl Me H cH, CHZCH~HCHz CHz 0 N- \
H H Al lyl Me H cH, CHzCH=CHCHz CHz N' H H CH2 Me H CH, CHzCH=CHCHz CHz p Cyclo- w N
Propyl CH3 CHzCH=CHCHz CHz Q
H H Butyl Me H
w N
CHa CH2CH=CHCHz CHz H H Sec-butyl Me H o w N

N' v R'' R' R' R" R' R° ~ R7 Compound Double bond configuration as per drawing GCH
~~N

~CH
~N
''\
H H Isopropyl H H
~CH
N
\
H H t-butyl H H
GCH
H H Vinyl H H
~CH
~N
\
H H Allyl H H °
GCH N
H H CH2 H H °
~CH
Cyclo- N
Propyl ~ \
H H Butyl H H GCH
w H H Sec-butyl ~ H H
~CH
~N
H H CH3 H H GCH \
N
H H CH3CH2 H H i'\CH \

H H CH3CH2CH2 H H GCH \
w N

Rl RZ R' R" R" R° R7 Compound Double bond configuration as per drawing H H Isopropyl H H /\CH \
N
H H t-butyl H H /\CH \
~ w~J, N
H H Vinyl H H /\CH \
N
H H Allyl H H ~CH \
N
H H CH2 H H ,/\CH \
Cyclo ~
Propyl N
b H H Butyl H H /\CH \
w~
N
H H Sec-butyl H H /\CH \
w~
N

N

\ o C.~N

R R R7 Compound Double bond configuration as per drawing ropyl H H GCH
~N
O'I
utyl H H ~ H N

nyl H H GCH
\

_1y1 H H GCH
\
- o ~H2 H H CI H
clo- N
opYl utyl H H GCH
~N
''\
O
-butyl H H GCH
~~~~ N

N

G
N

\ oII
N
~propyl H H CH

N-R1 RZ Rj R" R' R° R7 Compound Double bond configuration as per drawing H H t-butyl H H /\CH \
w N
H H Vinyl H H GCH \
w N
H H Allyl H H GCH
~N
H H CH2 H H /\CH \
cyclo ~-w propyl N
b H H Butyl H H GCH \
w N
H H Sec-butyl H H /\CH \
~w~J, N
Me Me CH3 H H
GCH
~\V~-~--~N
Me Me CH3CH2 H H °
GCH
o'°'' Me Me CH3CH2CH2 H H \ °
~N
G~H
'\

Rl R' R' R" R' R° R7 Compound Double bond configuration as per drawing Me Me Vinyl H H
~CH
Me Me Allyl H H
~CH
Me Me CH2 H H
CH
Cyclo- N
Propyl Me Me Butyl H H
H
~N
Me Me Sec-butyl H H ~CH
~,~~N
Me Me CH3 H H ~CH
I
Me Me CH3CH2 H H ~CH

N
Me Me CH3CH2CH2 H H GCH
/N
Me Me Isopropyl H H ~ ~CH

w w N
Me Me t-butyl H H ~CH
N
Me Me Vinyl H H GCH
N
J
Me Me Allyl H H CH

N

Rl R' R' R" R° R° R7 Compound Double bond configuration as per drawing Me Me CH2 H H GCH
Cyclo-Propyl Me Me Butyl H H
GCH ~\.~ o ~N
Me Me Sec-butyl H H
~CH o N
Me H CHS H Me ~ (CHs)zC=CHCHZCHz o I
Me H CH3CH2 H Me (CHs)zC=CHCHZCHz o ~N~
Me H CH3CH2CH2 H Me (CHa)zC=CHCHzCHz '( o w Me H Isopropyl H Me (CHa)zC=CHCHzCH2 0 N
Me H t-butyl H Me (CH3)2C=CHCHZCHZ o w Me H Vinyl H Me (CH3)2C=CHCH2CHz ' o w N
J
Me H Allyl H Me (CH3)iC=CHCHzCHz o w Me H CH2 H Me (CH3)ZC=CHCHZCHz o Cyclo- ~ N
Propyl Me H Butyl H Me (CH3)zC=CHCH2CH2 0 N
1~~

R R R R R R R7 Compound Double bond configuration as per drawing Me H Sec-butyl H Me (CHa)zC=CHCHzCHz o N
Me H CH3 H Me (CHz)ZC=CHCH2CHz I
Me H CH3CH2 H Me (CH3)zC=CHCHZCHZ
0iI
~N~
Me H CH3CH2CH2 H Me (CH~)zC=CHCHZCH '( I\~
0fI
N
Me H Isopropyl H Me I (CHsOC=CHCHZCHz 0'I
N
Me H t-butyl H Me (CH3)zC=CHCHzCHz I\
0'I
N
Me H Vinyl H Me (CHs)2C=CHCH2CH I\Z
0,I
N
I\J
Me H A11y1 H Me (CH,)~C=CHCH=CHZ
0'I
N
Me H CH2 H Me (CH3)2C=CHCHzCH2 Cyclo- o propyl Me H butyl H Me (CHz)ZC=CHCHZCHz N
1~1 Rl R' R' R" R' R° R7 Compound Double bond configuration as per drawing Me H Sec-butyl H Me (CHa)zC=CHCHZCHZ

N
Me H CH3 H Me (CH3)2C=CHCHZCHz o w I
Me H CH3CH2 H Me (CH3)zC=CHCHZCHZ o /N
Me H CH3CH2CH2 H Me (CHa)zC=CHCH2CH I(2 w N
Me H Isopropyl H Me (CHs)zC=CHCHZCHz w Me H t-butyl H Me (CH3)zC=CHCHzCHz w Me H Vinyl H Me (CH3)~C=CHCHZCHz -- o N
J
Me H Allyl H Me (CH3)zC=CHCHzCHz w N
Me H CH2 H Me (CH3)zC=CHCH2CHz Cyclo- ~ N
Propyl Me H Butyl H Me (CHs)zC=CHCHZCHz w N
Me H Sec-butyl H Me (CH3)zC=CHCH2CHz o N
Me H CH3 H Me (CH3)ZC=CHCHZCHZ
N- Y/
(/~
Me H CH3CH2 H Me (CH3)zC=CHCH~CHZ
i ,N- Y/

R R R R° R' R° R7 Compound Double bond configuration as per drawing Me H CH3CH2CH2 H Me (CH3)zC=CHCHzCHz ~N
Me H Isopropyl H Me (CH,)zC=CHCH2CH2 N T/
Me H t-butyl H Me (CH,),C=CHCHzCHz W
0I' N T/
Me H Vinyl H Me (CH;)zC=CHCHZCHz N
J
Me H Allyl H Me (CH,)2C=CHCHzCHz W

N T/
V
Me H CH2 H Me (CH;)ZC=CHCHzCH~
Cyclo- o propyl N
Me H butyl H Me (CH3)ZC=CHCHzCHz w N
Me H Sec-butyl H Me (CHs)zC=CHCH2CHz 0~I
N T/
Me H CH3 H Me (CH3)ZC=CHCHZCHZ
w N
Me H CH3CH2 H Me (CH3)zC=CHCHzCH2 0 ~N
Me H CH3CH2CH2 H Me (CH3)2C=CHCHzCH2 N
i R1 R' R' R" R' R° R7 Compound Double bond configuration as per drawing Me H Isopropyl H Me (CH;)zC=CHCHzCHz o N
Me H t-butyl H Me (CH,)zC=CHCHzCHz w N
Me H Vinyl H Me (CH;)zC=CHCHzCHz o w N
J
Me H Allyl H Me (CH3)zC=CHCH2CHz o w N
Me H CH2 _H Me (CH;)zC=CHCH,CHz o Cyclo- ~ N
Propyl C=CHCH,CHz Me H Butyl H Me (CN3)z w N
Me H Sec-butyl H Me (CH;)zC=CHCHZCHz o N
Me H CH3 H Me (CHs)zC=CHCH2CHz N
Me H CH3CH2 H Me (CHz)zC=CHCH2CHz ~N~
Me H CH3CH2CH2 H Me (CHs)zC=CHCH2CHz w .N
Me H Isopropyl H Me (CH;)zC=CHCHzCH /l\z N
Me H t-butyl H Me (CHs)zC=CHCH2CHz N

Rl R' R' R" R' R° R7 Coiapound Double bond configuration as per drawing Me H Vinyl H Me (CHs)zC=CHCHZCHz 0I' N
IJ
Me H Allyl H Me (CH;)zC=CHCH2CH2 N
Me H CH2 H Me (CHsOC=CHCHZCH l2 Cyclo- '~~ o propyl N
Me H butyl H Me (CH3)zC=CHCH2CHz w N
Me H Sec-butyl H Me (CH3)~C=CHCHZCH2 Me H CH3 H Me (CHz)2C=CHCHZCHz o N
Me H CH3CH2 H Me (CH3)zC=CHCHZCHZ o N.
Me H CH3CH2CH2 H Me (CHz)ZC=CHCHzCHz oII
N
Me H Isopropyl H Me (CH3)~C=CHCHzCH~ o N
Me H t-butyl H Me (CH3)zC=CHCHzCHz o N
Me H Vinyl H Me (CH3)zC=CHCHZCH2 0 N~
J
Me H Allyl H Me (CH3)2C=CHCHZCH2 0 N

R R R R° R' R° R7 Compound Double bond configuration as per drawing Me H CH2 H Me (CH3)zC=CHCHZCHz II
Cyclo- ~ N
Propyl Me H Butyl H Me (CH3)zC=CHCHZCH2 N
Me H Sec-butyl H Me (CH3)zC=CHCHzCHz oII
N
Me H CH.S H Me (CH3)zC=CHCHZCHZ

N
Me H CH3CH2 H Me (CHz)2C=CHCH~CHz W

N
Me H CH3CH2CH2 H Me (CH;)zC=CHCHzCHz w N
Me H Isopropyl H Me (CH3)zC=CHCHZCHz N
Me H t-butyl H Me (CH3)zC=CHCHZCHz N
Me H Vinyl H Me (CH3)zC=CHCHzCHz N v J
Me H Allyl H Me (CH3)ZC=CHCHzCH2 w N
Me H CH2 H Me (CH3)zC=CHCHzCHz Cyclo- o propyl N
i R1 R' R' R" R' R° R7 Compound Double bond configuration as per drawing Me H butyl H Me (CH;)zC=CHCH2CHz N
Me H Sec-butyl H Me (CHs)zC=CHCHZCHz N
Me H CH3 H Me (CHs)zC=CHCHzCHz o N
Me H CH3CH2 _H Me (CH3)zC=CHCH2CHz o N
Me H CH3CH2CH2 H Me (CH3)zC=CHCHZCHz o N
Me H Isopropyl H Me (CHs)zC=CHCH2CHz I' I o '~~,nN.~
Me H t-butyl H Me (CHs)zC=CHCHzCHz o N
Me H Vinyl H Me (CHs)zC=CHCHZCHz o N.
J
Me H Allyl H Me (CHz)zC=CHCHzCHz o'I
N
Me H CH2 H Me (CHs)aC=CHCHzCHz o Cyclo- ~ N
Propyl Me H Butyl H Me (CH3)zC=CHCH2CHz N
Me H Sec-butyl H Me (CH3)zC=CHCHZCHz o N

Rl R' R' R° R' R° R7 Compound Double bond configuration as per drawing Me H CH3 H Me (CHs)zC=CHCHZCHZ
N
Me H CH3CH2 H ~ Me I (CHs)zC=CHCHzCHz N
Me H CH3CH2CH2 H Me (~H3)zC=CHCHZCHz N
Me H Isopropyl ( H Me (CHs)zC=CHCHzCHz i N
J
Me H t-butyl H Me (CHs)zC=CHCHzCHz N
Me H Vinyl H Me (CHa)zC=CHCH2CHz I
N
J
Me H Allyl H Me (CHz)ZC=CHCHZCHZ
N
Me H CH2 H Me (CH~)zC=CHCHZCH2 Cyclo- '~'~'~ o propyl N
Me H butyl H Me (CH3)zC=CHCH2CHz w o N
Me H Sec-butyl H Me (CHs)zC=CHCHZCHz N
H cyclopropyl CH3 H H CHs(CHz)aCH=CHCHz CHz I

R R R R R R R7 Double bond configuration as per drawing H cyclopropyl CH3CH2 H H CH,(CH2)4CH=CHCHz CHz o w N
I
H cyclopropyl CH3CH2CH2 H H CH3(CH2)4CH=CHCH2 CHz o N
H cyclopropyl Isopropyl H H CHz(CHz)QCH=CHCHzCH2 0 N
[/
H cyclopropyl t-butyl ' H H CHz(CHZ)4CH=CHCHZ CH2 0 H cyclopropyl Vinyl H H CH3(CHz)4CH=CHCHz CHI o N
J

H cyclopropyl Allyl H H CH~(CHz)4CH=CHCHz CHI
N
H cyclopropyl CH2 H H CH3(CHz)4CH=CHCH2 CHz o Cyclo- ~ N
Propyl H cyclopropyl Butyl H H CHz(CH2)4CH=CHCH2 CHz N

R R R R R R R7 Double bond configuration as per drawing H cyclopropyl Sec-butyl H H CHz(CHz)4CH=CHCH2 CHz o w N
H cyclopropyl CH3 H H CHz(CH2)4CH=CHCH2 CHz O
N
VV
H cyclopropyl CH3CH2 H H CH~(CH2)4CH=CHCH~ CH2 w O
N 'C I
H cyclopropyl CH3CH2CH2 H H CHz(CHZ)4CH=CHCH2 CH2 N- 'C /
cyclopropyl Isopropyl H H CH,(CH~)4CH=CHCHzCHz N
H cyclopropyl t-butyl H H CH3(CHz)4CH=CHCHZ CHZ
O
N
H cyclopropyl Vinyl H H CH3(CHz)QCH=CHCHZ CHz N
VJ
H cyclopropyl Allyl H H CHz(CHz)QCH=CHCHZ CHZ

N

R~ Compound R R R R Rv Double bond configuration as per drawing cyclopropyl CH2 H H CH,(CHz)4CH=CHCH2 CH2 Cyclo- ~ o Propyl N
cyclopropyl Butyl H H CH,(CHZ)QCH=CHCHz CH2 N
H cyclopropyl Sec-butyl ~ H H CH~(CHz)4CH=CHCHZ CHZ

N
VV
H cyclopropyl CH3 H Me /~CH
N
\
O
H cyclopropyl CH3CH2 H Me /~CH
~N
O
H cyclopropyl CH3CH2CH2 H Me /~CH

H cyclopropyl Isoproyyl H Me /~CH
// ~ N
O
H cyclopropyl t-butyl H Me /~CH N

H cyclopropyl Vinyl H Me /~CH
N
\ J

H cyclopropyl Allyl H Me /~CH
H cyclopropYl CH2 H Me CH
Cyclo-~ Propyl -° CA 02518664 2005-09-09 R RE R~ compouna R R R R~ Double bond configuration as per drawing H cyclopropyl Butyl H Me /~CH
N
O
H cyclopropyl Sec-butyl H Me /~CH
H cyclopropyl CH3 H Me /~CH

N
H cyclopropyl CH3CH2 H Me /~CH
w w H cyclopropyl CH3CH2CH2 H Me /~CH
w N
H cyclopropyl Isopropyl H Me CH
w w ~N~
H cyclopropyl t-butyl H Me /~CH

N '( H cyclopropyl Vinyl H Me CH
w N
VVJ

Et R R R R R R7 Double bond configuration as per drawing H cyclopropyl Allyl H Me /~CH
I w N T/
H cyclopropyl CH2 H Me /~CH
Cyclo- Jew Propyl °II
N
H cyclopropyl Butyl H Me /~~H
w N
H cyclopropyl Sec-butyl H Me w N T/
H cyclopropyl CH3 H Me Me ~~
N '( /
V
H cyclopropyl CH3CH2 H Me Me H cyclopropyl CH3CH2CH2 H Me Me H cyclopropyl Isopropyl H Me N
H cyclopropyl t-butyl H Me Me N
H cyclopropyl Vinyl H Me I I III I

R R R R R R R7 Double bond configuration as per drawing H cyclopropyl Allyl H Me Me N
Me ~ O
H cyclopropyl CH2 H Me Cyclo Propyl H cyclopropyl Butyl H Me Me N
H cyclopropyl Sec-butyl H Me Me H cyclopropyl CH3 H H CH N
~~\~~~I~
- o H cyclopropyl CH3CH2 H H
\ ~~~~~~~~N
O
H cyclopropyl CH3CH2CH2 H H CH
\ ~~~~~~~~N
O
H cyclopropyl Isopropyl H H CH
\ ,,~,,.,~N
O
H cyclopropyl t-butyl H 1'~ CH
\ ~~~~~~~~N
O
H cyclopropyl Vinyl H H CH
\ ,C~~J ~
- o H cyclopropyl Allyl H H
,,1,,~,~N
H H
H cyclopropyl CH2 CH N
Cyclo- \
Propyl R R R R R R R7 Double bond configuration as per drawing H cyclopropyl Allyl H ~ H ~ \ CH
H cyclopropyl CH2 H H CH
Cyclo- W
Propyl ~o ~
N '( H cyclopropyl Butyl H H CH
I

N
VI
H cyclopropyl Sec-butyl H IH ~ CH

H H CH3 H Me /~CH
'N
\ I
O
H H CH3CH2 H Me /~CH
w H H CH3CH2CH2 H Me /~CH
JJ~~\ N
O
H H Isopropyl H Me /~CH N

H H t-butyl H Me /~CH
w H H Vinyl H Me /~CH N
\ v J

R R R R R R7 Double bond configuration as per drawing H H Allyl H Me /~CH
I v~ N
O
H H CH2 H Me //~CH
~N
Cyclo- \ \
Propyl H H Butyl H Me /~CH
J~ ~ N
O
H H Sec-butyl H Me /~CH
i H H CH3 H Me /~CH
\

N
H H CH3CH2 H Me /~CH

N
J
H H CH3CH2CH2 H Me //~CH

N
H H Isopropyl H Me /~CH
\

N
w H H t-butyl H Me CH

N

R R R R R R~ Double bond configuration as per dravring H H Vinyl H Me //~CH
w N
H H Allyl H Me /~CH
w w N
H H CH2 H Me //~CH
// w Cyclo- w Propyl o N
H H Butyl H Me /~CH
I w N
H H Sec-butyl H Me /~CH
y w N
I OII

w ~v I

J~J~" 1 H H Isopropyl H H CH

H H t-butyl H H CH

R R R R R R R~ Double bond configuration as per drawing H H Vinyl H H CH
\ ~~~ J

H H Allyi H H CH
I
\

N
Cyclo- \ \
Propyl H H Butyl H H CH
N
O
H H Sec-butyl H H CH
N

i w N

i N
J

i N
H H Isopropyl H H CH

N
H H t-butyl H H CH
i N

R R R R R R R7 Double bond configuration as per drawing H H Vinyl H H CH

N
J
H H Allyl H H CH
i N

Cyclo-Propyl ~ °II
N
H H Butyl H H CH
i N
H H Sec-Butyl H H CH
i N
H CH 3 H H CH, CH2CH=CHCHz CHz Me N~
Me H CH3CH2 H H cH, CHZCH=CHCHz CHz N
Me H CH3CH2CH2 H H CH,CHzCH=CHCHzCH2 N
H Isopropyl H H CH, CHzCH=CHCHz CH, °
Me Me H t-butyl H H CH, CHzCH=CHCHz CHz °

Compouna Double bond configuration as per drawing H H CH, CH2CH=CHCHz CHz o N
H H CH; CHzCH=CHCHz CHz o N
H H CH, CHzCH=CHCHz CHz o N
H H CH, CHZCH=CHCHz CHz --~N
1 H H CH, CHzCH=CHCHz CHz o N
H H CHz CHzCH=CHCHz CHz o N
H H CH, CHzCH=CHCHz CHz 0 N
H2 H H CH, CHzCH=CHCHz CHz o~
~N
y 1 H H CH, CHzCH=CHCHz CHz o N
'1 H H CH, CHzCH=CHCHz CHz o N
H H CH, CHzCH=CHCHz CHz o N
H H CH, CHZCH=CHCHz CHz o N

R R6 R7 compouna Double bond configuration as per drawing H H CH; CHZCH=CHCHz CHz o N
H H I CH, CHsCH=CHCHz CHz ~ o H H CH, CHzCH=CHCHz CHz o N
v H H CHs CHzCH=CHCHz CHz N
H H CH, CHzCH=CHCHz CHz N
2 H H CH, CH2CH=CHCHz CHz N
Z H H CH, CHzCH=CHCHz CHz N
_ H H CH, CHzCH=CHCHz CHz N
H H CH, CHzCH=CHCHz CH_ o N
H H CH, CH2CH=CHCHz CHz N
H H CH, CHZCH=CHCHz CHz o N
L
H H CH3 CH2CH=CHCHz CHz N

R R2 R3 R° R' R° R7 Compound Double bond configuration as per drawing H H S2C-blltyl H H CH,CHzCH~HCHzCHz N
H H CHI H H CH, CH2CH~HCHx CHz o~
N
H H C H 3 C H 2 H H CH3 CHzCH=CHCHx CNx o~
N
H H CH3CH2CH2 H H CH,CHzCH~HCHxCHx o~
N
H H Isopropyl H H cN,cHxCH=CHCHzCNx o~
N
H H t-butyl H H CH,CHZCH=CHCHxCHx o~
N
H H V i n y 1 H H CN, CHxCH=CHCHx CHx o~
N
H H Al l y1 H H CH, CHzCH~HCHz CHz N
H H CHL H H CH, CNzCH=CHCHx CHx Cyclo propyl H H Butyl H H CN, CN2CH=CHCHx CHi o~
N
H H Sec-butyl H H CH,CHxcH=CHCHzCHx o~
N

Other compounds of the present invention include the following according to Structure 5 above:
R1 R' R' R" R' R R7 Compound ~ Double bond configuration as per drawing H cyclopropyl H H Me ( CH; ) ~ C=CHCH2CH~o N
H

H H CH=CHI H H Me ( CH; ) 2 C=CHCH2CH2 H

H H CH ( CH; H H Me ( CH; ) ~ C=CHCHZCH~
_ ) Z H

H H H H H Me ( CH; ) ~ C=CHCHZCHZ

~N~

H

H H Me H H Me ( CH: ) ~ C=CHCH~CH~o N

H

H Me Me H H Me (CH;) a C=CHCH~CHzo N
H

H Cyclopropyl H H H CH;CH~ CH=CHCHZCH~o N
H

H H H Me H H CH;CH~ CH=CHCH~CH~o N~

The following compounds and Chemical Abstract (CA) names are provided for various compounds of the present invention.
Compound # Structure (Novel compounds)CA Index Name 2,6-nonadienamide, N-[(2E)-3,7-dimethyl-2,6-octadienyl]-, (2E,6Z)-2,6-nonadienamide, N-[(2Z)-3,7-H dimethyl-2,6-octadienyl]-, (2E,6Z)-p 2,6-octadienamide, N-[(2E)-3,7-w w dimethyl-2,6-octadienyl]-3,7-r r N dimethyl-, (2E)-H

2,6-octadienamide, N-[(2Z)-3,7-dimethyl-2,6-octadienyl]-3,7-n dimethyl-, (2E)-Compound # Structure (Novel compounds) CA Index Name 2,6-octadienamide, N-[(2E)-3,7-° ~ ~ dimethyl-2,6-octadienyl]-3,7-f", dimethyl-, (2Z)-2,6-octadienamide, N-[(2Z)-3,7-6 0 ~, dimethyl-2,6-octadienyl]-3,7-f", dimethyl-, (2Z)-7 w w 2,6-octadienamide, 3,7-dimethyl-N-[(2Z,6Z)-2,6-nonadienyl)-, (2E)-i 2,6-octadienamide, 3,7-dimethyl-N-,"i [(2Z,6Z)-2,6-nonadienyl]-, (2Z)-9 N Cyclopropanecarboxamide, N-" [(2Z,6Z)-2,6-nonadienyl]-w w N Cyclopropanecarboxamide, N-" [(2E,6Z)-2,6-nonadienyl)-11 H Cyclopropanecarboxamide, N-[(2E)-3-(3-cyclohexen-1-yl)-2-propenyl]-12 °
Cyclopropanecarboxamide, N-[(2Z)-s-" (3-cyclohexen-1-yl)-2-propenyl]-1'~ ~ ~ ~ N~ Cyclopropanecarboxamide,~ N-[ (2E)-2-"
methyl-3-phenyl-2-propenyl)-I\

Cyclopropanecarboxamide, N-[(2Z)-2-methyl-3-phenyl-2-propenyl]-\ ~ H~/ Cyclopropanecarboxamide, N-((2E)-3-phenyl-2-butenyl]-16 / °
Cyclopropanecarboxamide, N-[(2Z)-3-phenyl-2-butenyl]-o, ,, 1~ H Cyclopropanecarboxamide, N-[(2Z,6Z)-2-methyl-2,6-nonadienyl]-Compound # Structure (Novel compounds) CA Index Name 18 ~ ~ N~ Cyclopropanecarboxamide, N-" [(2E,6Z)-2-methyl-2,6-nonadienyl]-c 1g ~ ~ N Cyciopropanecarboxamide, N-[(2E)-~-I "~

w phenyl-2-propenyl]-~

Cyclopropanecarboxamide, N-[(2Z)-3-" phenyl-2-propenyl]-w w 1 H~ ropanamide, N-[(2E)-3,7-dimethyl-2,6-octadienyl]-2,2-dimethyl-N Propanamide, N-[(2Z)-3,7-dimethyl-" 2,6-octadienyl]-2,2-dimethyl-Butanamide, N-[(2E)-3,7-dimethyl-H 2,6-octadienyl]-Butanamide, N-[(2Z)-3,7-dimethyl-H 2,6-octadienyl]-25 ~ w I H Propanamide, N-[(2E)-2-methyl-3-phenyl-2-propenyl]-i 26 ~
Propanamide, N-[(2Z)-2-methyl-3-phenyl-2-propenyl]-27 ~
~

~ ~ Propanamide, N-[(2E)-3-phenyl-2-H

butenyl]-I

28 ' o Propanamide, N-[(22)-3-phenyl-2-H butenyl)-29 ~ H~ Acetamide, N-[(2E)-2-methyl-3-\ I phenyl-2-propenyl]-Compound # Structure (Novel compounds)CA Index Name I

30 ~
II Acetamide, N-[(2Z)-2-methyl-3-" phenyl-2-propenyl]-cII
31 i ~
~

N Acetamide, N-[(2E)-3-phenyl-2-H

butenyl]-I

32 ~ Acetamide, N-[(2Z)-3-phenyl-2-H butenyl]-33 ~ id N

Acetam -[( e, Z,6Z)-2-methyl-2,6-H nonadienyll-34 ~ ~ N~ Acetamide, N-[(2E,6Z)-2-methyl-2,6-H nonadienyl]-35 H~ Propanamide, N-[(2E)-3-(3-cyclohexen-1-yl)-2-propenyl)-Propanamide, N-[(2Z)-3-(3-H cvclohexen-1-yl)-2-propenyl]-7 ~

N Acetamide, N-[(2E)-3-(3-cyclohexen-H

1-yl)-2-propenyl]-w Acetamide, N-[(2Z)-3-(3-cyclohexen-H 1-yl)-2-propenyl]-Propanamide, N-[(2E)-3-(3-39 ~ cyclohexen-1-yl)-2-propenyl]-2,2-h l di met y -Propanamide, N-[(2Z)-3-(3-cyclohexen-1-yl)-2-propenyl]-2,2-dimethyl-utanamide, N-[(2E)-3,7-dimethyl-2,6-octadienyl]-2-methyl-Compound # Structure (Novel compounds) CA Index Name 42 N Butanamide, N-[(2Z)-3,7-dimethyl-H
2,6-octadienyl]-2-methyl-43 w w N~ Cyclopropanecarboxamide, N-[(2E)-3,7-dimethyl-2,6-octadienyl]-a N Cyclopropanecarboxamide, N-[(2Z)-H 3,7-dimethyl-2,6-octadienyl]-45 ~ ~ N Propanamide, N-[(2E)-3,7-dimethyl-2,6-octadienyl]-2-methyl-46 Propanamide, N-[(2Z)-3,7-dimethyl-N
H 2,6-octadienyl]-2-methyl-0!' 2-butenamide, N-[(2E)-3,7-dimethyl-2,6-octadienyl]-, (2E)-48 , 2-butenamide, N-[(2Z)-3,7-dimethyl-2,6-octadienyl]-, (2E)-2-butenamide, N-[(2E)-3,7-dimethyl-2,6-octadienyl]-3-methyl-50 \ ~ °
2-butenamide, N-[(2Z)-3,7-dimethyl-H 2,6-octadienyl]-3-methyl-51 ~ ~ N~ Cyclopropanecarboxamide, N
" [(2E,6Z)-2,6-dodecadienyl]
Cyclopropanecarboxamide, N-[(2E)-3 52 N (4-methyl-3-cyclohexen-1-yl)-2-H
butenyl]-I
53 Cyclopropanecarboxamide, N-[(2Z)-3-N (9-methyl-3-cyclohexen-1-yl)-2-" butenyl]-Compound # Structure (Novel compounds)CA Index Name H Cyclopropanecarboxamide, N-(3-methyl-2-butenyl)-55 ~ N Cyclopropanecarboxamide, N-[(2E)-H (2,6,6-trimethyl-3-cyclohexen-1-yl)-2-butenyl]-56 Cyclopropanecarboxamide, N-[(2Z)-(2,6,6-trimethyl-3-cyclohexen-1-yl)-2-butenyl]-5~ ~ Cyclopropanecarboxamide, N-[(2E)-(2,4-dimethyl-3-cyclohexen-1-l)-2-y propenyl]-~l 58 ~ Cyclopropanecarboxamide, N-[(2Z)-(2,4-dimethyl-3-cyclohexen-1-yl)-2-~

" propenyl]-59 ~

Acetamide N -( y H i -((2E)-3 4-meth 1-3-cyclohexen-1-yl)-2-butenyl]-w Acetamide, N-[(2Z)-3-(4-methyl-3-" cyclohexen-1-yl)-2-butenyl]-61 ~ ~ Acetamide, N-[ (2E)-3-(2, 6, H trimethyl-3-cyclohexen-1-yl)-2-butenylj-~ _ Acetamide, N-[(2Z)-3-(2,6,6-trimethyl-3-cyclohexen-1-yl)-2-butenyl]-63 ~

Acetamide N , y --[(2E)-3-(2 4-dimeth 1 3-cyclohexen-1-yl)-2-propenyl]-Acetamide, N-[(2Z)-3-(2,4-dimethyl-H 3-cyclohexen-1-yl)-2-propenyl]-Cyclopropanecarboxamide, N-[[2-~ ~ methyl-2-(9-methyl-3-pentenyl)cyclopropyl]methyl]-Compound # Structure (Novel compounds)CA Index Name o Cyclopropanecarboxamide, N-[[2-66 w ~ [(3z)-3-N

hexenyl]cyclopropyl]methyl]-68 \ ~

Propanamide, N-[(2Z)-3,7-dimethyl-H 2,6-octadienyl]-w w cetamide, N-[(2Z)-3,7-dimethyl-H 2,6-octadienyl]-71 ~ Cyclopropanecarboxamide, N-methyl-N N-[(2Z,6Z)-2,6-nonadienyl]-72 ~ Cyclopropanecarboxamide, N-ethyl-N-[(2Z,6Z)-2,6-nonadienyl]-73 ~ Cyclopropanecarboxamide, N-N [(2Z,6Z)-2,6-nonadienyl]-N-propyl-7g ~ Cyclopropanecarboxamide, N-(1-N methylethyl) -N-[(2Z,6Z)-2,6-nonadienyij-Cyclopropanecarboxamide., N-(1,1-dimethylethyl) -N-[(2Z,6Z)-2,6-nonadienyl]-~ Cyclopropanecarboxamide, N-ethenyl-N-[(2Z,6Z)-2,6-nonadienyl]-77 ~ Cyclopropanecarboxamide, N-N [(2Z,6Z)-2,6-nonadienyl]-N-(2-propenyl)-78 Cyclopropanecarboxamide, N-N (cyclopropylmethyl) -N-((2Z,6Z)-2,6-nonadienyl]-79 Cyclopropanecarboxamide, N-butyl-N-N [(2Z,6Z)-2,6-nonadienyl]-w Compound # Structure (Novel compounds) CA Index Name 8~ °~ Cyclopropanecarboxamide, N-[(2Z,6Z)-2,6-nonadienyl]-N-(2-methylpropyl) 81 ~ o Cyclopropanecarboxamide, N-methyl-N-[(2E,6Z)-2,6-nonadienyl]-N
82 0 ~Cyclopropanecarboxamide, N-ethyl-N-propyl-84 (1-85 (1~1-2, 6_ g6 2thenyl-8~ \ o Cyclopropanecarboxamide, N-((2E,6Z)-2,6-nonadieryl]-N-(2-propenyl)-88 I o ICyclopropanecarboxamide, N-(cyclopropylmethyl) -N-[(2E,6Z)-2,6-nonadienyl]-89 o Cyclopropanecarboxamide, N-butyl-N-[(2E,62)-2,6-nonadienyl]-o Cyclopropanecarboxamide, N-[(2E,6Z)-2,6-nonadienyl]-N-(2-methylpropyl)-I
91 o Cyclopropanecarboxamide, N-methyl- I
N N-[(2E)-3-(3-cyclohexen-1-yl)-2 propenyl]-Compound # Structure (Novel compounds)CA Index Name 92 Cyclopropanecarboxamide, N-ethyl-N N-[(2E)-3-(3-cyclohexen-1-yl)-2-propenyl]-93 Cyclopropanecarboxamide, N-[(2E)-3-N (3-cyclohexen-1-yl)-2-propenyl]-N-propyl 9q Cyclopropanecarboxamide, N-(1-methylethyl)- N-[(2E)-3-(3-cyclohexen-1-yl)-2-propenyl]-95 Cyclopropanecarboxamide, N-(1,1-dimethylethyl)-N-((2E)-3-(3-cyclohexen-1-yl)-2-propenyl]-96 I Cyclopropanecarboxamide, N-ethenyl-N N-[(2E)-3-(~-cyclohexen-1-yl)-2-propenyl]-o Cyclopropanecarboxamide, N-[(2E)-3-N (3-cyclohexen-1-yl)-2-propenyl]-N-(2-propenyl)-98 o Cyclopropanecarboxamide, N-N (cyclopropylmethyl) - N-((2E)-3-(3-cyclohexen-I-yl)-2-propenyl]-99 o Cyclopropanecarboxamide, N-butyl-N-N [(2E)-3-(3-cyclohexen-1-yl)-2-propenyl]-100 Cyclopropanecarboxamide, N-[(2E)-3-N (3-cyclohexen-1-yl)-2-propenyl]-N-(2-methylpropyl)-101 ~ Cyclopropanecarboxamide, N-methyl-N-[(2Z)-3-(3-cyclohexen-1-yl)-2-II propenyl]-N

102 w Cyclopropanecarboxamide, N-ethyl-N-[(2Z)-3-(3-cyclohexen-1-yl)-2-propenyl]-~ N

103 w Cyclopropanecarboxamide, N-[(2Z)-3-(3-cyclohexen-1-yl)-2-propenyl]-N-propyl-\ N

Compound # Structure (Novel compounds)CA Index Name 104 w Cyclopropanecarboxamide, N-(1-methylethyl)-N-[(2Z)-3-(3-cyclohexen-1-yl)-2-propenyl]-\ N

105 ,~ Cyclopropanecarboxamide, N-(1,1-dimethylethyl)-N-[(2Z)-3-(3-cyclohexen-1-yl)-2-N propenyl]-106 w Cyclopropanecarboxamide, N-ethenyl-N-[(2Z)-3-(3-cyclohexen-1-yl)-2-propenyl]-\

N

107 w Cyclopropanecarboxamide, N-[(2Z)-3-(3-cyclohexen-1-yl)-2-propenyl]-N-(2-propenyl)-\

N

108 ~ Cyclopropanecarboxamide, N-(cyclopropylmethyl)- N-[(2Z)-3-(3-o cyclohexen-1-yl)-2-propenyl]-\ N

109 w Cyclopropanecarboxamide, N-butyl-N-[(2Z)-3-(3-cyclohexen-1-yl)-2-propenyl]-\ N

110 w Cyclopropanecarboxamide, N-[(2Z)-3-(3-cyclohexen-1-yl)-2-propenyl]-N-(2-methylpropyl)-\ N

111 Cyclopropanecarboxamide, N-methyl-N N-[(2E)-2-methyl-3-phenyl-2-propenyl]-112 Cyclopropanecarboxamide, N-ethyl-N-i I ~ N [(2E)-2-methyl-3-phenyl-2-propenyl]-113 Cyclopropanecarboxamide, N-[(2E)-2-i ~ N methyl-3-phenyl-2-propenyl]-N-propyl Compound # Structure (Novel compounds) CA Index Name 114 ~ Cyclopropanecarboxamide, N-(1-methylethyl)- N-[(2E)-2-methyl-3-phenyl-2-propenyl]-115 ° Cyclopropanecarboxamide, N-(l,l-w N dimethylethyl)-N-[(2E)-2-methyl-3-phenyl-2-propenyl]-116 o Cyclopropanecarboxamide, N-ethenyl-N N-[(2E)-2-methyl-3-phenyl-2-propenyl]-117 ° Cyclopropanecarboxamide, N-[(2E)-2-i ~ N methyl-3-phenyl-2-propenyl]-N-(2-propenyl)_ 118 o Cyclopropanecarboxamide, N-[(2E)-2-w N methyl-3-phenyl-2-propenyl]-N-(cyclopropylmethyl)-119 o Cyclopropanecarboxamide, N-butyl-N-i ~ N [(2E)-2-methyl-3-phenyl-2-propenyl]-120 o Cyclopropanecarboxamide, N-[(2E)-2-N methyl-3-phenyl-2-propenyl]-N-(2-~ methylpropyl)-121 w Cyclopropanecarboxamide, N-methyl-N-[(2Z)-2-methyl-3-phenyl-2-propenyl]-\ N
122 w Cyclopropanecarboxamide, N-ethyl-N-[(2Z)-2-methyl-3-phenyl-2-propenyl]-\ N
J
123 ~ Cyclopropanecarboxamide, N-[(2Z)-2-methyl-3-phenyl-2-propenyl]-N-propyl \ N
124 w Cyclopropanecarboxamide, N-(1-methylethyl)- N-[(2Z)-2-methyl-3-phenyl-2-propenyl]-w Compound # Structure (Novel compounds) CA Index Name 125 I w Cyclopropanecarboxamide, N-(1,1-dimethylethyl)-o N-[(2Z)-2-methyl-3-phenyl-2-propenyl]-126 Cyclopropanecarboxamide, N-ethenyl-N-[(2Z)-2-methyl-3-phenyl-2-propenyl]-\ N
J
127 I w Cyclopropanecarboxamide, N-[(2Z)-2-methyl-3-phenyl-2-propenyl]-N-(2-propenyl)-\ N
128 ~ Cyclopropanecarboxamide, N-(cyclopropylmethyl) -N-[(2Z)-2-° methyl-3-phenyl-2-propenyl]-\ N
b 129 I w Cyclopropanecarboxamide, N-butyl-N-[(2Z)-2-methyl-3-phenyl-2-propenyl]-\ N
130 I w Cyclopropanecarboxamide, N-[(2Z)-2-methyl-3-phenyl-2-propenyl]-N-(2-° methylpropyl)-N
I
131 ° Cyclopropanecarboxamide, N-[(2E)-3-i ~ N phenyl-2-butenyl]-N-methyl-132 Cyclopropanecarboxamide, N-[(2E)-3-i ~ N phenyl-2-butenyl]-N-ethyl-J
133 Cyclopropanecarboxamide, N-[(2E)-3-i ~ N phenyl-2-butenyl]-N-propyl-Compound # Structure (Novel compounds) CA Index Name 134 ° Cyclopropanecarboxamide, N-[(2E)-3-~ N phenyl-2-butenyl]-N-(1-methylethyl)-135 o Cyclopropanecarboxamide, N-[(2E)-3-i ~ N phenyl-2-butenyl]-N-(1,1-dimethylethyl)-136 ° Cyclopropanecarboxamide, N-[(2E)-3-i ~ N phenyl-2-butenyl]-N-ethenyl-~I
137 ° Cyclopropanecarboxamide, N-[(2E)-3-i ~ N phenyl-2-butenyl]-N-(2-propenyl)-138 o Cyclopropanecarboxamide, N-[(2E)-3-i ~ N phenyl-2-butenyl]-N-(cyclopropylmethyl)-139 o Cyclopropanecarboxamide, N-[(2E)-3-~ N phenyl-2-butenyl]-N-butyl-w 140 ° Cyclopropanecarboxamide, N-[(2E)-3-i ~ N phenyl-2-butenyl]-N-(2-methylpropyl)-141 I ~ ~Cyclopropanecarboxamide, N-[(2Z)-3-phenyl-2-butenyl]-N-methyl-N
V
142 I w Cyclopropanecarboxamide, N-[(2Z)-3-phenyl-2-butenyl]-N-ethyl-N
143 I w Cyclopropanecarboxamide, N-[(2Z)-3-phenyl-2-butenyl]-N-propyl-\ N
144 I w Cyclopropanecarboxamide, N-[(2Z)-3-phenyl-2-butenyl]-N-(1-methylethyl)-\ N

Compound # Structure (Novel compounds) CA Index Name 145 I w Cyclopropanecarboxamide, N-((2Z)-3-phenyl-2-butenyl]-N-(1,1-dimethylethyl)-\ N
146 ~ w Cyclopropanecarboxamide, N-[(2Z)-~-phenyl-2-butenyl]-N-ethenyl-\ N
147 ! w Cyclopropanecarboxamide, N-[(2Z)-3-phenyl-2-butenyl]-N-(2-propenyl)-\ N
148 I w Cyclopropanecarboxamide, N-[(22)-..
phenyl-2-butenyl]-N-(cyclopropylmethyl)-\ N
149 ~ w Cyclopropanecarboxamide, N-[(2Z)-3-phenyl-2-butenyl]-N-butyl-\ N
150 I w Cyclopropanecarboxamide, N-[(2Z)-3-phenyl-2-butenyl]-N-(2-methylpropyl)-\ N
151 °~ Cyclopropanecarboxamide, N-methyl-N N-[(2Z,6Z)-2-methyl-2,6-nonadienyl]-152 °~ Cyclopropanecarboxamide, N-ethyl-N-N [(2Z,6Z)-2-methyl-2,6-nonadienyl]-153 ° Cyclopropanecarboxamide, N- I!
N [(2Z,6Z)-2-methyl-2,6-nonadienyl]-N-propyl-154 ° Cyclopropanecarboxamide, N-(1-N methylethyl)- N-[(2Z,6Z)-2-methyl-2,6-nonadienyl]-Compound # Structure (Novel compounds)CA Index Name 155 ~ Cyclopropanecarboxamide, N-(2-N methylpropyl)-N-[(2Z,6Z)-2-methyl-2,6-nonadienyl]-156 ~ Cyclopropanecarboxamide, N-ethenyl-N N-[(2Z,6Z)-2-methyl-2,6-nonadienyl]-157 ~ Cyclopropanecarboxamide, N-N [(2Z,6Z)-2-methyl-2,6-nonadienyl]-N-(2-propenyl)-' 158 o Cyclopropanecarboxamide, N-(cyclopropylmethyl) -N-[(2Z,6Z)-2-~ methyl-2,6-nonadienyl]-159 ~ Cyclopropanecarboxamide, N-butyl-N-N [(2Z,6Z)-2-methyl-2,6-nonadienyl]-160 ~ Cyclopropanecarboxamide, N-N [(2Z,6Z)-2-methyl-2,6-nonadienyl]-N-(2-methylpropyl)-161 Cyclopropanecarboxamide, N-methyl-N-[(2E,6Z)-2-methyl-2,6-N nonadienyl]-I

162 Cyclopropanecarboxamide, N-ethyl-N-[(2E,6Z)-2-methyl-2,6-nonadienyl]-N
J

163 Cyclopropanecarboxamide, N-[(2E,62)-2-methyl-2,6-nonadienyl]-N N-propyl-164 Cyclopropanecarboxamide, N-(1-methylethyl)-N-[(2E,6Z)-2-methyl-N 2,6-nonadienyl]-165 o Cyclopropanecarboxamide, N-(1,1-dimethylethyl)-N N-[(2E,6Z)-2-methyl-2,6-nonadienyl]-166 o Cyclopropanecarboxamide, N-ethenyl-~ ~ N-[(2E,6Z)-2-methyl-2,6-nonadienyl]
N- 1"/

Compound # Structure (Novel compounds) CA Index Name 167 Cyclopropanecarboxamide, N-[(2E,6Z)-2-methyl-2,6-nonadienyl]-N~ N-(2-propenyl)-168 ~ Cyclopropanecarboxamide, N-(cyclopropylmethyl) -N-[(2E,6Z)-2-N~ methyl-2,6-nonadienyl]-169 Cyclopropanecarboxamide, N-butyl-~ , N-[(2E,6Z)-2-methyl-2,6-N
nonadienyl]-170 Cyclopropanecarboxamide, N-[(2E,6Z)-2-methyl-2,6-nonadienyll_-N N-(2-methylpropyl)-171 Cyclopropanecarboxamide, N-methyl-N-[(2E)-3-phenyl-2-propenyl]-172 Cyclopropanecarboxamide, N-ethyl-N-[(2E)-3-phenyl-2-propenyl]-173 Cyclopropanecarboxamide, N-[(2E)-3-N phenyl-2-propenyl]-N-propyl-174 Cyclopropanecarboxamide, N-(1-~ methylethyl)-N-[(2E)-3-phenyl-2-~ N

I propenyl]-175 Cyclopropanecarboxamide, N-(1,1-i dimethylethyl)- N-[(2E)-3-phenyl-2-~ N

I propenyl]-176 Cyclopropanecarboxamide, N-ethenyl-N N-[(2E)-3-phenyl-2-propenyl]-~I

177 Cyclopropanecarboxamide, N-[(2E)-3-phenyl-2-propenyl]-N-(2-propenyl)-178 ~ Cyclopropanecarboxamide, N-N (cyclopropylmethyl) -N-[(2E)-3-phenyl-2-propenyl]-Compound # Structure (Novel compounds) CA Index Name 179 o Cyclopropanecarboxamide, N-butyl-N-N [(2E)-3-phenyl-2-propenyl]-180 o Cyclopropanecarboxamide, N-[(2E)-3-N phenyl-2-propenyl]-N-(2-methylpropyl)-181 ~ Cyclopropanecarboxamide, N-methyl-N-[(2Z)-3-phenyl-2-propenyl]-\ N' ~/
182 ~ Cyclopropanecarboxamide, N-ethyl-N-[(2Z)-3-phenyl-2-propenyl]-\ N
183 ~ Cyclopropanecarboxamide, N-[(2Z)-3-phenyl-2-propenyl]-N-propyl-\ N-[/
184 ~ Cyclopropanecarboxamide, N-(1-methylethyl)-N-[(2Z)-3-phenyl-2-propenyl]-\ N
185 ~ Cyclopropanecarboxamide, N-(l,l-dimethylethyl)- N-[(2Z)-3-phenyl-2-° propenyl]-\ N
186 ~ Cyclopropanecarboxamide, N-ethenyl-N-[(2Z)-3-phenyl-2-propenyl]-\ N
J
187 ~ Cyclopropanecarboxamide, N-[(2Z)-3-phenyl-2-propenyl]-N-2-propenyl-\ N

Compound # Structure (Novel compounds) CA Index Name 188 - ~ Cyclopropanecarboxamide, N-(cyclopropylmethyl) -N-[(2Z)-3-phenyl-2-propenyl]-\ N
189 ~ Cyclopropanecarboxamide, N-butyl-N-[(2Z)-3-phenyl-2-propenyl]-\ N-190 w Cyclopropanecarboxamide, N-[(2Z)-3-phenyl-2-propenyl]-N-(2-methylpropyl)-\ N
191 ~ o Propanamide, N-methyl-N-[(2E)-3,7-N dimethyl-2,6-octadienyl]-2,2-(~ dimethyl-192 Propanamide, N-ethyl-N-[(2E)-3,7-dimethyl-2,6-octadienyl]-2,2-dimethyl-193 Propanamide, N-[(2E)-3,7-dimethyl-N 2,6-octadienyl]-N-propyi-2,2-dimethyl-194 I c Propanamide, N-(1-methylethyl)-N-N [(2E)-3,7-dimethyl-2,6-octadienyl]-2,2-dimethyl-195 Propanamide, N-(1,1-dimethylethyl)-N-[(2E)-3,7-dimethyl-2,6-octadienyl]-2,2-dimethyl-196 Propanamide, N-ethenyl-N-[(2E)-3,7-N dimethyl-2,6-octadienyl]-2,2-dimethyl-19~ Propanamide, N-[(2E)-3,7-dimethyl-N 2,6-octadienyl]-N-(2-propenyl)-2,2-dimethyl-o Propanamide, N-(cyclopropylmethyl)-N N-[(2E)-3,7-dimethyl-2,6-octadienyl]-2,2-dimethyl-Compound # Structure (Novel compounds)CA Index Name 199 Propanamide, N-butyl-N-((2E)-3,7-N dimethyl-2,6-octadienyl]-2,2-dimethyl-o Propanamide, N-[(2E)-3,7-dimethyl-N 2,6-octadienyl]-N-(2-methylpropyl)-2,2-dimethyl-20I Propanamide, N-methyl-N-[(2Z)-3,7-dimethyl-2,6-octadienyl]-2,2-N dimethyl-I

202 Propanamide, N-ethyl-N-[(2Z)-3,7-dimethyl-2,6-octadienyl]-2,2-N dimethyl-203 Propanamide, N-[(2Z)-3,7-dimethyl-w o 2,6-octadienyl]-N-propyl-2,2-dimethyl-N

204 Propanamide, N-(1-methylethyl)-N-[(2Z)-3,7-dimethyl-2,6-octadienyl]-N 2,2-dimethyl-205 Propanamide, N-(1,1-dimethylethyl)-N-[(2Z)-3,7-dimethyl-2,6-octadienyl]-2,2-dimethyl-N

206 Propanamide, N-ethenyl-N-[(2Z)-3,7-o dimethyl-2,6-octadienyl]-2,2-dimethyl-N

207 Propanamide, N-[(2Z)-3,7-dimethyl-~ ~ 0 2,6-octadienyl]-N-(2-propenyl)-2,2-N dimethyl-U

208 Propanamide, N-(cyclopropylmethyl)-o N-[(2Z)-3,7-dimethyl-2,6-N octadienyl]-2,2-dimethyl-209 Propanamide, N-butyl-N-[(2Z)-3,7-dimethyl-2,6-octadienyl]-2,2-dimethyl-N

Compound # Structure (Novel compounds)CA Index Name 210 Propanamide, N-[(2Z)-3,7-dimethyl-2,6-octadienyl]-N-(2-methylpropyl)-N 2,2-dimethyl-211 I' Butanamide, N-methyl-N-[(2E)-3,7-N~ dimethyl-2,6-octadienyl]-I

212 Butanamide, N-ethyl-N-[(2E)-3,7-N dimethyl-2,6-octadienyl]-213 Butanamide, N-[(2E)-3,7-dimethyl-N 2,6-octadienyl]-N-propyl-214 II Butanamide, N-(1-methylethyl)-N-N~ [(2E)-3,7-dimethyl-2,6-octadienyl]-215 II Butanamide, N-(1,1-dimethylethyl)-N~ N-[(2E)-3,7-dimethyl-2,6-octadienyl]-216 ~ Butanamide, N-ethenyl-N-[(2E)-3,7-N dimethyl-2,6-octadienyl]-217 Butanamide, N-[(2E)-3,7-dimethyl-N 2,6-octadienyl]-N-(2-propenyl)-218 ~~ Butanamide, N-(cyclopropylmethyl)-N~ N-[(2E)-3,7-dimethyl-2,6-octadienyl]-219 II Butanamide, N-butyl-N-[(2E)-3,7-N~ dimethyl-2,6-octadienyl]-220 II Butanamide, N-[(2E)-3,7-dimethyl-N~ 2,6-octadienyl]-N-(2-methylpropyl)-221 Butanamide, N-methyl-N-[(2Z)-3,7-I' dimethyl-2,6-octadienyl]-N

Compound # Structure (Novel compounds)CA Index Name 222 Butanamide, N-ethyl-N-[(2Z)-3,I-oII dimethyl-2,6-octadienyl]-N

223 Butanamide, N-[(2Z)-3,7-dimethyl-0II 2,6-octadienyl]-N-propyl-N

224 Butanamide, N-(1-methylethyl)-N-o,I [(2Z)-3,7-dimethyl-2,6-octadienyl]-N

225 Butanamide, N-(l,l-dimethylethyl)-o N-[(2Z)-3,7-dimethyl-2,6-N~ octadienyl]-226 Butanamide, N-ethenyl-N-[(2Z)-3,7-dimethyl-2,6-octadienyl]-N

227 Butanamide, N-[(2Z)-3,7-dimethyl-2,6-octadienyl]-N-(2-propenyl)-N

228 Butanamide, N-(cyclopropylmethyi)-o N-[(2Z)-3,7-dimethyl-2,6-octadienyl]-N

229 Butanamide, N-butyl-N-[(2Z)-3,7-dimethyl-2,6-octadienyl]-~N

230 Butanamide, N-[(2Z)-3,7-dimethyl-2,6-octadienyl]-N-(2-methylpropyl)-N

231 ~~~ Propanamide, N-methyl-N-[(2E)-2-~ m th l-3-hen 1]-N y I p y propeny e 232 ~~~ Propanamide, N-ethyl-N-[(2E)-2-N!'/ methyl-3-phenyl-2-propenyl]-Compound # Structure (Novel compounds)CA Index Name 233 ofI Propanamide, N-[(2E)-2-methyl-3-~ hen l-2-ro en l]-N-ro N p y p p y p py w 234 ~~ Propanamide, N-(1-methylethyl)-N-N~ [(2E)-2-methyl-3-phenyl-2-ro en 1)-p p y 235 ~ Propanamide, N-(1,1-dimethylethyl)-N-[(2E)-2-meth h i ~ N y p eny propenyl]-236 [~ Propanamide, N-ethenyl-N-[(2E)-2-~ meth l-3-hen l-2-ro en 1)-N y p y p p y w 237 Propanamide, N-[(2E)-2-methyl-3-hen l-2-ro en 1]-N-(2--w ~ y p p p y propeny ) Propanamide, N-(cyclopropylmethyl)-238 ~ N-[(2E)-2-meth h l-2-~ ~ N y p eny en l]-ro y p p 239 ~~ Propanamide, N-butyl-N-[(2E)-2-~ meth l-3-hen l-2-ro 1)-N y p y p peny w 240 ~~ Propanamide, N-[(2E)-2-methyl-3-~ l-2-h n l]-N-i ~ N propeny p e y ( meth l ro 1)-y p py 241 w Propanamide, N-methyl-N-[(2Z)-2-methyl-3-phenyl-2-propenyl)-0'' \ N

242 w Propanamide, N-ethyl-N-[(2Z)-2-methyl-3-phenyl-2-propenyl)-\ N' v 243 w Propanamide, N-[(2Z)-2-methyl-3-phenyl-2-propenyl]-N-propyl-\ N- v Compound # Structure (Novel compounds)CA Index Name 244 ~ Propanamide, N-(1-methylethyl)-N-I [(2Z)-2-methyl-3-phenyl-2-propenyl]-\ N

245 ~ Propanamide, N-(1-methylethyl)-N-[(2Z)-2-methyl-3-phenyl-2-propenyl]-\ N

246 w Propanamide, N-ethenyl-N-[(2Z)-2-methyl-3-phenyl-2-propenyl]-\ N' v 247 ~ Propanamide, N-[(2Z)-2-methyl-3-I phenyl-2-propenyl]-N-2-propenyl-\ N_ v 248 ~ Propanamide, N-(cyclopropylmethyl)-N-[(2Z)-2-methyl-3-phenyl-2-propenyl]-\ N

249 w Propanamide, N-butyl-N-[(2Z)-2-I methyl-3-phenyl-2-propenyl]-\ N- v 250 ~, Propanamide, N-[(2Z)-2-methyl-3-phenyl-2-propenyl]-N-(2-methylpropyl)-\ N

251 oII Propanamide, N-[(2E) -3-phenyl-2-i ~ N~ butenyl]- N-methyl-252 o Propanamide, N-[(2E) -3-phenyl-2-i ~ N butenyl]- N-ethyl-253 ~II Propanamide, N-[(2E) -3-phenyl-2-~ l]-N-buten ro N p y py w Compound # Structure (Novel compounds)CA Index Name 254 oII Propanamide, N-[(2E) -3-phenyl-2-~ N~ butenyl]-N-(1-methylethyl)-255 o Propanamide, N-[(2E) -3-phenyl-2-i ~ N butenyl]-N-(1,1-dimethylethyl)-~I
I

256 Propanamide, N-[(2E) -3-phenyl-2-i ~ N butenyl]-N-ethenyl-~i Propanamide, N-[(2E) -3-phenyl-2-257 ~ ~ N butenyl]-N-(2-propenyl)-258 o Propanamide, N-[(2E) -3-phenyl-2-i ~ N butenyl]-N-(cyclopropylmethyl)-259 Propanamide, N-[(2E) -3-phenyl-2-i ~ N butenyl]-N-butyl-260 ~~ Propanamide, N-[(2E) -3-phenyl-2-i ~ N~ butenyl]-N-(2-methylpropyl)-261 ~ Propanamide, N-[(2Z) -3-phenyl-2-butenyl]-N-methyl-'~N~

262 w Propanamide, N-[(2Z) -3-phenyl-2-butenyl]-N-ethyl-\ N

263 ~ Propanamide, N-[(2Z) -3-phenyl-2-butenyl]-N-propyl-\ N

264 w Propanamide, N-[(2Z) -3-phenyl-2-butenyl]-N-(1-methylethyl)-\ N

Compound # Structure (Novel compounds)CA Index Name 265 ~ Propanamide, N-[(2Z)- 3-phenyl-2-butenyl]-N-(1,1-dimethylethyl)-\ N-266 w Propanamide, N-[(2Z) -3-phenyl-2-butenyl]-N-ethenyl-\ N

267 ~ Propanamide, N-[(2Z) -3-phenyl-2-butenyl]-N-(2-propenyl)-\ N

268 w Propanamide, N-[(2Z) -3-phenyl-2-butenyl]-N-(cyclopropylmethyl)-\ N.

269 w Propanamide, N-[(2Z)- 3-phenyl-2-~ , butenyl]-N-butyl-N

270 w Propanamide, N-((2Z) -3-phenyl-2-I butenyl]-N-(2-methylpropyl)-\ N

271 o Acetamide, N-methyl-N-[(2E)-2-~I
~ l-3-hen l-2-ro en meth 1]-I w i p p p y y y 272 Acetamide, N-ethyl-N-[(2E)-2-hen l-2-ro en meth 1]-y p p y y p 273 I[ Acetamide, N-[(2E)-2-methyl-3-~

i I ~ N phenyl-2-propenyl]-N-propyl-w 274 oII Acetamide, N-(1-methylethyl)-N-~ [(2E)-2-meth l-3-hen N y p y propenyl]-Compound # Structure (Novel compounds)CA Index Name 275 Acetamide, N-(1,1-dimethylethyl)-N-[(2E)-2-meth hen w N y y p propenyl]-276 oII Acetamide, N-ethenyl-N-[(2E)-2-~ meth l-3-hen l-2-ro en 1]-i w N y p y p p y L-277 o Acetamide, N-[(2E)-2-methyl-3-hen 1]-N-(2--y propeny p propeny ) 278 Acetamide, N-(cyclopropylmethyl)-N-[(2E)-2-meth l-3-hen N y p y en ro 1]-y p p 279 oII Acetamide, N-butyl-N-[(2E)-2-~ meth l-3-he l-2-ro l -w N y p p peny ny ]

280 II Acetamide, N-[(2E)-2-methyl-3-~ n l-2-l)-N-(2-h l I ~ N y propeny p e m th ro 1)-l y py e p 281 ~ Acetamide, N-methyl-N-[(2Z)-2-methyl-3-phenyl-2-propenyl]-\ N' \

282 w Acetamide, N-ethyl-N-[(2Z)-2-~~ methyl-3-phenyl-2-propenyl)-0fI
\ N

283 w Acetamide, N-[(2Z)-2-methyl-3-phenyl-2-propenyl]-N-propyl-\ N

284 w Acetamide, N-(1-methylethyl)-N-[(2Z)-2-methyl-3-phenyl-2-propenyl]-\

N

285 w Acetamide, N-(l,l-dimethylethyl)-N-[(2Z)-2-methyl-3-phenyl-2-propenyl]-\ N

Compound # Structure (Novel compounds) CA Index Name 286 I ~ Acetamide, N-ethenyl-N-[(2Z)-2-methyl-3-phenyl-2-propenyl]-O
N
287 - ~ Acetamide, N-[(2Z)-2-methyl-3-phenyl-2-propenyl]-N-(2-propenyl)-N
288 ~ Acetamide, N-(cyclopropylmethyl)-N-[(22)-2-methyl-3-phenyl-2-o propenyl]-N
v 2g9 ~ Acetamide, N-butyl-N-[(2Z)-2-methyl-3-phenyl-2-propenyl]-N
290 w Acetamide, N-[(2Z)-2-methyl-3-phenyl-2-propenyl]-N-(2-methylpropyl)-N
291 o Acetamide, N-[(2E)-3-phenyl-2-i ~ N butenyl]-N-methyl-292 o Acetamide, N-[(2E)-3-phenyl-2-i I ~ N butenyl]-N-ethyl-w 293 oII Acetamide, N-((2E)-3-phenyl-2-i ~ N~ butenyl]-N-propyl-o Acetamide, N-[(2E)-3-phenyl-2-294 ~ ~ N~ butenyl]-N-(1-methylethyl)-o Acetamide, N-[(2E)-3-phenyl-2-295 ~ ~ N~ butenyl]-N-(l,l-dimethylethyl)-296 oII Acetamide, N-[(2E)-3-phenyl-2-i ~ N~ butenyl]-N-ethenyl)-Compound # Structure (Novel compounds)CA Index Name 297 oiI Acetamide, N-[(2E)-3-phenyl-2-i- ~ N~ butenyl]-N-(2-propenyl)-298 ~ oiI Acetamide, N-((2E)-3-phenyl-2-i ~ N~ butenyl]-N-(cyclopropylmethyl)-' ~I

299 oII Acetamide, N-[(2E)-3-phenyl-2-~~ l]-N-b ~ t t b N u eny u y 300 ' oII Acetamide, N-[(2E)-3-phenyl-2-~ i]-N-(2-~ b t th l l -i u N eny me y propy ) I

301 w Acetamide, N-[(2Z)-3-phenyl-2-butenyl]-N-methyl-N

302 ~ Acetamide, N-[(2Z)-3-phenyl-2-butenyl]-N-ethyl-N

303 ~ Acetamide, N-[(2Z)-3-phenyl-2-butenyl]-N-propyl-N

I

304 w Acetamide, N-[(2Z)-3-phenyl-2-butenyl]-N-(1-methylethyl)-N- \

305 ~ Acetamide, N-[(22)-3-phenyl-2-butenyl]-N-(l,l-dimethylethyl)-w N

306 ~ Acetamide, N-[(2Z)-3-phenyl-2-butenyl]-N-ethenyl)-N

Compound # Structure (Novel compounds)CA Index Name 307 w Acetamide, N-[(2Z)-3-phenyl-2-butenyl]-N-(2-propenyl)-N

308 ~ Acetamide, N-[(2Z)-3-phenyl-2-butenyl]-N-(cyclopropylmethyl)-N

b 309 ~ Acetamide, N-[(2Z)-3-phenyl-2-butenyl]-N-butyl-N

310 ~ Acetamide, N-[(2Z)-3-phenyl-2-butenyl]-N-(2-methylpropyl)-N

311 ~ Acetamide, N-methyl-N-[(2Z,6Z)-2-N methyl-2,6-nonadienyl]-I

~ Acetamide, N-ethyl-N-[(2Z,6Z)-2-N methyl-2,6-nonadienyl]-313 ~ Acetamide, N-[(2Z,6Z)-2-methyl-2,6-N nonadienyl]-N-propyl-314 ~ Acetamide, N-(1-methylethyl)-N-[(2Z,62)-2-methyl-2,6-nonadienyl]-315 ~ Acetamide, N-(1,1-dimethylethyl)-N-[(2Z,6Z)-2-methyl-2,6-nonadienyl]-316 ~ Acetamide, N-ethenyl-N-[(2Z,6Z)-2-methyl-2,6-nonadienyl]-317 ~ Acetamide, N-[(2Z,6Z)-2-methyl-2,6-N nonadienyl]-N-(2-propenyl)-Compound # Structure (Novel compounds)CA Index Name 318 ~ Acetamide, N-(cyclopropylmethyl)-N-N [(2Z,6Z)-2-methyl-2,6-nonadienyl]-319 ~ Acetamide, N-butyl-N-[ (2Z, 6Z)-2-~ methyl-2,6-nonadienyl]-N

~

320 ~ Acetamide, N-[(2Z,6Z)-2-methyl-2,6-N nonadienyl]-N-(2-methylpropyl)-321 o Cyclopropylcarboxamide, N-methyl-N-((2E,6Z)-2-methyl-2,6-nonadienyl]-322 o Cyclopropylcarboxamide, N-ethyl-N-((2E,6Z)-2-methyl-2,6-nonadienyl]-~ ~'/

323 o Cyclopropylcarboxamide, N-[(2E,6Z)-2-methyl-2,6-nonadienyl)-N-propyl-N

324 ~ o Cyclopropylcarboxamide, N-(1-methylethyl)-N-[(2E,6Z)-2-methyl-~

~N 2,6-nonadienyl]-325 o Cyclopropylcarboxamide, N-(1,1-dimethylethyl)-N-((2E,6Z)-2-methyl-2,6-nonadienyl]-326 ~ o Cyclopropylcarboxamide, N-ethenyl-N-((2E,6Z)-2-methyl-2,6-~

N nonadienyl]-327 o Cyclopropylcarboxamide, N-[(2E,6Z)-I

2-methyl-2,6-nonadienyl]-N-(2-N
propenyl)-328 o Cyclopropylcarboxamide, N-(cyclopropylmethyl)-N-((2E,6Z)-2-N methyl-2,6-nonadienyl]-329 o Cyclopropylcarboxamide, N-butyl-N-[(2E,6Z)-2-methyl-2,6-nonadienyl)-Compound # Structure (Novel compounds)CA Index Name 330 Cyclopropylcarboxamide, N-[(2E,6Z)-c-methyl-2,6-nonadienyl]-N-(2-N meth i ro 1)-Y P Py 331 I ~ Fropanamide, N-methyl-N-[(2E)-~-(~-~ cyciohexen-1-yi)-2-propenyl]-~~N~
w 332 'I Proparamide, N-ethyl-N-[(2E)-~-(3-cyclohexen-1-yl)-2-propenyl]-w %

333 j ~ Propanamide, N-[(2E)-3-(~-N~' cyclohexen-1-yl)-2-propenyli-N-~~ propyi-334 Propar_~amide, N-(i-methylethyl)-N-~ ~

,, [ ( 2E ) --- ( ~-cyclchexen-i-lrl ) -2-proper_~yl i -335 II Fropanamide, N-(i,i-dimethyiethvl)-~N~ N-[(2E)-3-(3-cyclohexen-1-yi)-2-propenyll_-33E ~ I Propanamide, N-ethenyl-N-((2E)-~ !
~-l h l , ( ~ cyc o exen--y )-2-properyil-~ i 337 Prcpanamide, N-[(2E)-3-(~-~N cycichexen-1-yl)-2-propenyll-N-(2-i ~~~ propenyl ) -i I

33~ .' ~ FrcpGnamide, N-(cyclcprcpyimethyi)-N N-[(2E)-~-(3-cyclohexen-1-yl)-2-propenyl]-339 ~~
Propanamide, N-butyl-N-[(2E)-3-(3-~ l h 1)-2-N o exen cyc y propenyl]-340 o'I Propanamide, N-[(2E)-3-(3-~

N cyclohexen-1-yl)-2-propenyl]-N-(2-methylpropyl)-341 ~ Propanamide, N-methyl-N-[(2Z)-3-(3-cyclohexen-1-yl)-2-propenyl]-\ N

(Compound # Structure (Novel compounds)CA Index Name ~

3Q~ ~ Propanamide, N-ethyl-N-[(2Z)-3-(3-cyclohexen-1-yl)-2-propenyl]-I

~N~
I

343 ~, ~ Propanamide, N- [ (2Z)-3- ( i cyclohexen_-1-yl)-c-propenyl~-N-I

propyl-N

344 , Propanamide, N-(1-methylethyl)-IV-[(2Z)-~-(~-cyclohexen-1-yl)-2-I propenyl]-i \ N I

I, ~ I j 34~ ( ~ ~ Frcpanamide, N-(1,1-dimethylethyl)-I

i _2_ N-[(22)-_-(-cyclohexen-1-yi;~

~ prcpenyl]- i N i I

346 \ Froponamide, N-ethenyl-N-[(2Z)-3-(3-cyclohexen-1-yl)-2-propenyl]-\ b N

i I
' Pro anamide, N-[(2Z)-3-(~-3 4 ;~ i ~~ ~ p Icyclohexen-1-_yl)-2-propenyli-N-(2-c I
l -I ~ / propeny \ N- ) i i 348 ' ~~ ~ Prepanamide, N-(cyclopropylmethyl)-j ~ l,r.-[(2Z)-?-(~-cyclohexen-i-yl)-~-Ipropenyi~_ i b I

349 w Propanamide, N-butyl-N-[(2Z)-3-(3-cyclohexen-1-yl)-2-propenyl]-N.

350 I ~ Propanamide, N-[(2Z)-3-(3-I cyclohexen-1-yl)-2-propenyl]-N-(2-methylpropyl)-N

IS$

-. I
Compound # Structure (Novel compounds)CA Index Name 351 ~ Acetamide, N-methyl-N-[(2E)-3-(3-lohexen-1-l)-2-ll i i j y I cyc propeny -352 ~ I Acetamide, N-ethyl-N-[(2E)-3-(3-~ cyclohexen-_-yl ) -2-properly /~/~/~N~ ~ 1 i -I i I

353 Acetamide, N-[(2E)-3-(3-cyciohexen-I
ro en l)-2-ij-N-i-l-i y p p y propy ~ AcetGmide, N-(1-methylethyl)-N-~
~

~N [(2E)-2-(Z-cyclohexen-i-yl)-2-~ I

~ propenyl]-i i ~ ACet2mide, N-(i,1-dimethylethyl)-N-n [(2E;-~-(Z-cyclohexen-1-yi)-2-I

prcpe:~y1 ] -( _ 356 0 ~ Acetamide, N-ethenyl-N-[(2E)-2-(~-i h l o exen y ) cyc propenylj-a Acetamide, N-[(2E)-3-(3-cyclohexen-i /~/~N _-yl)-~-propenyl]-N-(2-propenyl)-, ~~, 358 ~ ~ oII Acetamide, N-(cyclopropyimethyl)-~

~N [(2E)-3-(3-cyclohexen-1-y11-2-i ~ ~ ~ propenylj-U
i 359 ~ ~ ~ Acetarr~~ ae, N-outy-N- [
( 2E ) -~- ( 3-r~N~ ~cycichexer.-i-yl)-c-prepenyli-360 oII Acetamide, N-((2E)-3-(3-cyclohexen-~

N 1-yl)-2-propenyl]-N-(2-methylpropyl)-361 ~ Acetamide, N-methyl-N-[(2Z)-3-(3-I cyclohexen-1-yl)-2-propenyl]-~N~

362 ~ Acetamide, N-ethyl-N-[(2Z)-~-(3-cyclohexen-1-yl)-2-propenyl]-\ N

i I
Compound # Structure (Novel compounds)CA Index Name 363 ~ y Acetamide, N-[(2Z)-3-(3-cyclohexen-1-yl ) -2-propenyl ] -N-propyi -w i N

I i 364 j F_cetamide, N- (1-methyiethyl ) -N-[(2Z)-3-(~-cyclohexen-1-yl)-~-i~ ~ propenyll-/\

365 I ~ Acetamide, N-(1,1-dimethyiethyl)-N-~~ I [(2Z)-3-(~-cyclohexen-1-yl)-~-j Ipropenyl!-N

366 ' ~; jAcetamide, N-ethenyl-N-[(2Z)-~-(~-I icyclohexen-i-yl)-2-prcpenyli-I ~N~ i i I
i ~ I

367 w Acetamide, N-[(22)-3-(3-cyciohexen-1-yl)-2-propenyl]-N-(2-propenyl)-I W N-'\

I

368 I . IAcetamide, N-(cyclopropylmethyl)-N-[ ( 2Z ) -..- ( ~-cyclohexen-1-yl ) -2-~\~ propenyii-~
~

N

i ~ ~Acetamide, N-butyl-N-[(2Z)-_-(3-365 ~

j i ;c~-clchexer-i-yl)-2-prcpenyl~-~N ~ I

370 ~ Acetamide, N-[(2Z)-3-(3-cyclohexen-1-yl)-2-propenyl]-N-(2-methylpropyl)-\ N

o Fropanamide, N-methyl-N-[(2E)-3-(~-~ c clohexen-1 1 -2 p y N Y -y ) -pro en 1)-2,2-dimethyl-Compound # &tructure (Novel compounds)CA Index Name 372 Propanamide, N-ethyl-N-[(2E)-3-('?-cyclchexen-1-yl)-2-propenyl]-2,2-dimethyl-373 j ~ PropGnamide, N-[(2E)-3-(?-cyclchexen-1-yi)-2-prcpenyl]-N-propyl-2,2-drmethyl- j Propanamide, N-(1-methylethyl)-N-G
37_ [(2E)-2-(3-cyclohexen-1-yl)-2-propenyll-2,2-dimethyi-375 ~ PropGnemide, N-(l,i-dimethylethyl)-N-[(2E)-=-(3-cyclohexen-I-yl)-2-' ~ propenyll_-2,2-dimethyl-y / /W

37 6 I o ~ Fropanarr~.ide, N-a thenyi-R-[ ( 2E ) -~ (~-cyclohexen-i-yl)-2-propenyii-2,2-dimethyl-377 Propanamide, N-[(2E)-~-(~- I

cyciohexen-1-yl)-2-propenyl]-N-(2-propenyl)-2,2-dimethyl-378 PropanGmide, N-(cyclopropylmethyi)-N-[(2E)-~-(2-cyclchexen-i-yl)-2-propenyl]-2,2-dimethyl-379 ! ~ Propanamide, N-butyl-N-[(2E)-3-(3-Icyclohexen.-i-yl)-2-propenyll-2,2-~dimethy1-j 380 ~ ~ ~ Prcpa:~amide, Iv-[ (2E)-~-(?-i j cyclohexen-1-yl)-2-propenyl]-N-(2-methylpropyl)-2 2-dimethyl-, 381 o Propanamide, N-methyl-N-[(2Z)-3-(3-~ cyclohexen-1-yl)-2-propenyl]-2,2-dimethyl-382 ~ o Propanamide, N-ethyl-N-[(2Z)-3-(~-cyclohexen-1-yl)-2-propenyl]-2,2-dimethyl-383 o Propanamide, N-[(2Z)-3-(3-~ cyclohexen-1-yl)-2-propenyl]-N-propyl-2,2-dimethyl-Compound # Structure (Novel compounds)CA Index Name 384 I ~ c Propanamide, N-(1-methylethyl)-N-' I [(2Z)-3-(3-cyclohexen-1-yl)-2-propenyl]-2,2-dimethyl-I

38' ~ o I Fropanamide, N-(1,1-dimethylethyl)-p N-[(22)-3-(3-cyclohexen-1-yl)-2-!

~ propenyli-2,2-dimethyl-i -fi 386 ~, c, Propanamide, N-ethenyl-N-[(22)-I f\ ! (3-cyclohexen-1-yl)-2-propenyl]-2,2-dimethyi-38i ~ o Fropanamide, N-[(2Z)-3-(3-cyclohexen-1-yl)-2-propenyl]-N-(2-propenyl)-2,2-dimethyl-:~88 ~ o Fropanamide, N-(cyclopropylmethyl)-y ', N-((2Z;-3-(~-cyclohexen-1-yl)-2-h I propenyl]-2,2-dimethyi-' 389 c Fropanamide, N-butyl-N-[(2Z)-3-(3-cyclohexen-1-yl)-2-propenyll-2,2-N dimethyl-!3gG - i ~' c Propanamide, N-[(22)-3-(3-~

i ~ ~: ' ~ cyclchexen-1-yi)-2-prcpenyl]-N-(2-j I imetuylpropyl)-2,2-dimethyl-~A1 I ! IButanamide, N-methyl-N-[(2E)-3,7-idimethyl-2,6-octadienyl]-2-methyl-i i a I
I

1 392 ~ ~ ~ ~ ButGnamiae, N-ethyl-N-[ (2E;-, I ~ ~ ~ i- i ~ciimethyi-2,6-octadienyl]-2-methyl-I

I

393 Butanamide, N-[(2E)-3,7-dimethyl-2,6-octadienyl]-N-propyl-2-methyl-o Butanamide, N-(1-methylethyl)-N-((2E)-3,7-dimethyl-2,6-octadienyl]-2-methyl-395 Butanamide, N-(1,1-dimethylethyl)-N-((2E)-3,7-dimethyl-2,6-octadienyl]-2-methyl-Compound # Structure (Novel compounds)CA Index Name 396 i Butanamide, N-ethenyl-N-((2E)-3,7-dimethyl-2,6-octadienyl]-2-methyl-397 I I Butanamide, N-[(2E)-3,7-dimethyl-2,6-octadienyl]-N-(2-propenyl)-2-methyl-398 Butanamide, N-(cyclopropylmethyl)-N N-[(2E)-3,7-dimethyl-2,6-octadienyl]-2-methyl-399 ~ ~ o Butanamide, N-butyl-N-[(2E)-3,7-N dimethyl-2,6-octadienyl]-2-methyl-400 ~ Butanamide, N-[(2E)-3,7-dimethyl-N 2,6-octadienyl]-N-(2-methylpropyl)-2-methyl-401 Butanamide, N-methyl-N-[(2Z)-3,7-oII dimethyl-2,6-octadienyl]-2-methyl-N
I

402 'Butanamide, N-ethyl-N-[(2Z)-3,7-oII dimethyl-2,6-octadienyl]-2-methyl-~N~

403 Butanamide, N-[(2Z)-3,7-dimethyl-2,6-octadienyl]-N-propyl-2-methyl-N

404 Butanamide, N-(1-methylethyl)-N-o [(2Z)-3,7-dimethyl-2,6-octadienyl]-2-methyl-N

405 Butanamide, N-(1,1-dimethylethyl)-o N-[(2Z)-3,7-dimethyl-2,6-octadienyl)-2-methyl-N

406 Butanamide, N-ethenyl-N-[(2Z)-3,7-oII dimethyl-2,6-octadienyl]-2-methyl-N
I\J

Compound # Structure (Novel compounds)CA Index Name 407 Butanamide, N-[(2Z)-3,7-dimethyl-0 2,6-octadienyl]-N-(2-propenyl)-2-methyl-N

408 Butanamide, N-(cyclopropylmethyl)-N-[(2Z)-3,7-dimethyl-2,6-N octadienyl]-2-methyl-409 Butanamide, N-butyl-N-[(2Z)-3,7-oI' dimethyl-2,6-octadienyl]-2-methyl-~N~

410 Butanamide, N-[(2Z)-3,7-dimethyl-0 2,6-octadienyl]-N-(2-methylpropyl)-2-methyl-N

411 Cyclopropanecarboxamide, N-methyl-N N-[(2E)-3,7-dimethyl-2,6-octadienyl]-412 Cyclopropanecarboxamide, N-ethyl-N-N [(2E)-3,7-dimethyl-2,6-octadienyl]-413 Cyclopropanecarboxamide, N-[(2E)-N 3,7-dimethyl-2,6-octadienyl)-N-propyl-414 Cyclopropanecarboxamide, N-(1-N methylethyl)-N-[(2E)-3,7-dimethyl-2,6-octadienyl]-415 Cyclopropanecarboxamide, N-(l,l-N dimethylethyl)-N-[(2E)-3,7-dimethyl-2,6-octadienyl]-416 Cyclopropanecarboxamide, N-ethenyl-N-[(2E)-3,7-dimethyl-2,6-octadienyl]-417 Cyclopropanecarboxamide, N-[(2E)-3,7-dimethyl-2,6-octadienyl]-N-2-propenyl-418 Cyclopropanecarboxamide, N-N (cyclopropylmethyl) -N-[(2E)-3,7-dimethyl-2,6-octadienyl)-Compound # Structure (Novel compounds)CA Index Name 419 Cyclopropanecarboxamide, N-butyl-N-N [(2E)-3,7-dimethyl-2,6-octadienyl]-420 Cyclopropanecarboxamide, N-[(2E)-N 3,7-dimethyl-2,6-octadienyl]-N-(2-methylpropyl)-421 Cyclopropanecarboxamide, N-methyl-N-[(2Z)-3,7-dimethyl-2,6-N octadienyl]-I

422 Cyclopropanecarboxamide, N-ethyl-N-w Q [(2Z)-3,7-dimethyl-2,6-octadienyl]-~N~
[[//

423 Cyclopropanecarboxamide, N-[(2Z)-w 3,7-dimethyl-2,6-octadienyl]-N-ProPYl_ ~N

424 Cyclopropanecarboxamide, N-(1-w methylethyl)-N-[(2Z)-3,7-dimethyl-N 2,6-octadienyl]-425 Cyclopropanecarboxamide, N-(1,i-w o dimethylethyl)-N-[{2Z)-3,7-N dimethyl-2,6-octadienyl]-426 Cyclopropanecarboxamide, N-ethenyl-N-[(2Z)-3,7-dimethyl-2,6-N octadienyl]-J

427 Cyclopropanecarboxamide, N-[(2Z)-0 3,7-dimethyl-2,6-octadienyl]-N-2-N propenyl-428 Cyclopropanecarboxamide, N-w o (cyclopropylmethyl) -N-[(2Z)-3,7-N dimethyl-2,6-octadienyl]-429 Cyclopropanecarboxamide, N-butyl-N-w [(2Z)-3,7-dimethyl-2,6-octadienyl]-~N~

Compound # Structure (Novel compounds)CA Index Name 430 Cyclopropanecarboxamide, N-[(2Z)-3,7-dimethyl-2,6-octadienyl]-N-(2-methylpropyl)-431 ~ Propanamide, N-methyl-N-((2E)-3,7-dimethyl-2,6-octadienyl]-2-methyl-I

432 Propanamide, N-ethyl-N-[(2E)-3,7-dimethyl-2,6-octadienyl]-2-methyl-433 Propanamide, N-[(2E)-3,7-dimethyl-fN 2,6-octadienyl]-N-propyl-2-methyl-434 ~ Propanamide, N-(1-methylethyl)-N-[(2E)-3,7-dimethyl-2,6-octadienyl]-2-methyl-435 Propanamide, N-(l,l-dimethylethyl)-N-((2E)-3,7-dimethyl-2,6-octadienyl]-2-methyl-436 I Propanamide, N-ethenyl-N-[(2E)-3,7-~ dimethyl-2,6-octadienyl]-2-methyl-437 Propanamide, N-[(2E)-3,7-dimethyl-L,6-octadienyl]-N-(2-propenyl)-2-methyl-438 Propanamide, N-(cyclopropylmethyl)-N N-[(2E)-3,7-dimethyl-2,6-octadienyl]-2-methyl-439 Propanamide, N-butyl-N-[(2E)-3,7-N dimethyl-2,6-octadienyl]-2-methyl-440 ~ Propanamide, N-[(2E)-3,7-dimethyl-2,6-octadienyl]-N-(2-methylpropyl)-2-methyl-441 Propanamide, N-methyl-N-[(2Z)-3,7-o~~ dimethyl-2,6-octadienyl]-2-methyl-N
II

Compound # Structure (Novel compounds)CA Index Name 442 Propanamide, N-ethyl-N-[(2Z)-3,7-o dimethyl-2,6-octadienyl]-2-methyl-.N
'( 443 Propanamide, N-[(2Z)-3,7-dimethyl-II 2,6-octadienyl]-N-propyl-2-methyl-N

444 Propanamide, N-(1-methylethyl)-N-w o [(2Z)-3,7-dimethyl-2,6-octadienyl]-2-methyl-N

445 Propanamide, N-(1,1-dimethylethyl)-w o N-[(2Z)-3,7-dimethyl-2,6-octadienyl]-2-methyl-N

446 Propanamide, N-ethenyl-N-[(2Z)-3,7-o dimethyl-2,6-octadienyl]-2-methyl-J

447 Propanamide, N-[(2Z)-3,7-dimethyl-w o 2,6-octadienyl]-N-(2-propenyl)-2-methyl-N

448 Propanamide, N-(cyclopropylmethyl)-o N-[(2Z)-3,7-dimethyl-2,6-N octadienyl]-2-methyl-449 Propanamide, N-butyl-N-[(2Z)-3,7-o dimethyl-2,6-octadienyl]-2-methyl-~N~
I

450 Propanamide, N-[(2Z)-3,7-dimethyl-0 2,6-octadienyl]-N-(2-methylpropyl)-2-methyl-451 2-butenamide, N-methyl-N-[(2E)-3,7-N dimethyl-2,6-octadienyl]-, (2E)-I

452 II 2-butenamide, N-ethyl-N-[(2E)-3,7-N~ dimethyl-2,6-octadienyl]-, (2E)-Compound # Structure (Novel compounds)CA Index Name 453 2-butenamide, N-[(2E)-3,7-dimethyl-N 2,6-octadienyl]-N-propyl-, (2E)-454 II 2-butenamide, N-(1-methylethyl)-N-~ [(2E)-3,7-dimethyl-2,6-octadienyl]-N~

(2E)-455 II 2-butenamide, N-(1,1-N~ dimethylethyl)-N-[(2E)-3,7-dimethyl-2,6-octadienyl]-, (2E)-456 ~ 2-butenamide, N-ethenyl-N-[(2E)-N ~ 3,7-dimethyl-2,6-octadienyl]-, (2E)_ 457 ~~ 2-butenamide, N-[(2E)-3,7-dimethyi-N~ 2,6-octadienyl]-N-(2-propenyl)-, (2E)-458 Ii 2-butenamide, N-N~ (cyclopropylmethyl)-N-[(2E)-3,7-dimethyl-2,6-octadienyl]-, (2E)-459 'I 2-butenamide, N-butyl-N-[(2E)-3,7-~N~ dimethyl-2,6-octadienyl]-, (2E)-460 2-butenamide, N-[(2E)-3,7-dimethyl-N 2,6-octadienyl]-N-(2-methylpropyl)-(2E) -461 I 2-butenamide, N-methyl-N-[(2Z)-3,7-dimethyl-2,6-octadienyl]-, (2E)-II
N

462 2-butenamide, N-ethyl-N-[(2Z)-3,7-dimethyl-2,6-octadienyl]-, (2E)-N

463 2-butenamide, N-[(2Z)-3,7-dimethyl-w ~ 2,6-octadienyl]-N-propyl-, (2E)-N

464 2-butenamide, N-(1-methylethyl)-N-[(2Z)-3,7-dimethyl-2,6-octadienyl]-N~ . (2E) _ Compound # Structure (Novel compounds)CA Index Name 465 2-butenamide, N-(l,i-o dimethylethyl)-N-[(2Z)-3,7-N~ dimethyl-2,6-octadienyl]-, (2E)-466 2-butenamide, N-ethenyl-N-[(2Z)-w o 3,7-dimethyl-2,6-octadienylj-, (2E) _ 467 2-butenamide, N-[(2Z)-3,7-dimethyl-0 2,6-octadienyl]-N-(2-propenyl)-, (2E) _ 468 2-butenamide, N-a (cyclopropylmethyl)-N-[(2Z)-3,7-N~ dimethyl-2,6-octadienyl]-, (2E)-469 2-butenamide, N-butyl-N-[(2Z)-3,7-o dimethyl-2,6-octadienyl]-, (2E)-N

470 2-butenamide, N-[(2Z)-3,7-dimethyl-0 2,6-octadienyl]-N-(2-methylpropyl)-N~ . (2E)-471 0 2-butenamide, N-methyl-N-[(2E)-3,7-N dimethyl-2,6-octadienyl]-3-methyl-I

472 ~ 2-butenamide, N-ethyl-N-[(2E)-3,7-N dimethyl-2,6-octadienyl]-3-methyl-473 ~II ~/ 2-butenamide, N-[(2E)-3,7-dimethyl-N~ 2,6-octadienyl]-N-propyl-3-methyl-474 ~ 2-butenamide, N-(1-methylethyl)-N-N [(2E)-3,7-dimethyl-2,6-octadienyl]-3-methyl-475 ~ 2-butenamide, N-(l,l-N dimethylethyl)-N-[(2E)-3,7-dimethyl-2,6-octadienyl]-3-methyl-476 2-butenamide, N-ethenyl-N-[(2E)-N ~ 3,7-dimethyl-2,6-octadienyl]-3-methyl-Compound # Structure (Novel compounds)CA Index Name 477 ~ 2-butenamide, N-[(2E)-3,7-dimethyl-N 2,6-octadienyl]-N-(2-propenyl)-3-methyl-478 2-butenamide, N-N ~ (cyclopropylmethyl)-N-((2E)-3,7-dimethyl-2,6-octadienyl]-3-methyl-479 ~ 2-butenamide, N-butyl-N-[(2E)-3,7-N dimethyl-2,6-octadienyl]-3-methyl-480 ~ 2-butenamide, N-[(2E)-3,7-dimethyl-N 2,6-octadienyl]-N-(2-methylpropyl)-3-methyl-481 2-butenamide, N-methyl-N-[(2Z)-3,7-o dimethyl-2,6-octadienyl]-3-methyl-N- '"

482 2-butenamide, N-ethyl-N-((2Z)-3,7-o dimethyl-2,6-octadienyl]-3-methyl-N

983 2-butenamide, N-[(2Z)-3,7-dimethyl-0 2,6-octadienyl]-N-propyl-3-methyl-N

484 . 2-butenamide,.N-(1-methylethyl)-N-o [(2Z)-3,7-dimethyl-2,6-octadienyl]-N 3-methyl-485 2-butenamide, N-(1,1-o dimethylethyl)-N-[(2Z)-3,7-N dimethyl-2,6-octadienyl]-3-methyl-486 2-butenamide, N-ethenyl-N-[(2Z)-0 3,7-dimethyl-2,6-octadienyl]-3-N methyl-487 ~ 2-butenamide, N-[(2Z)-3,7-dimethyl-0 2,6-octadienyl]-N-(2-propenyl)-3-N methyl-Compound # Structure (Novel compounds) CA Index Name 488 2-butenamide, N-w o , (cyclopropylmethyl)-N-[(2Z)-3,7-N~ dimethyl-2,6-octadienyl]-3-methyl-489 2-butenamide, N-butyl-N-[(2Z)-3,7-o dimethyl-2,6-octadienyl]-3-methyl-N

490 2-butenamide, N-[(2Z)-3,7-dimethyl-0 2,6-octadienyl]-N- (2-methylpropyl)-N 3-methyl-491 o Cyclopropanecarboxamide, N-~ ~ [(2E,6Z)-2,6-dodecadienyl]-N-i' Y/ methyl-[/

492 ~ Cyclopropanecarboxamide, N-((2E,6Z)-2,6-dodecadienyl]-N-ethyl-493 o Cyclopropanecarboxamide, N-~ [(2E,6Z)-2,6-dodecadienyl]-N-~ propyl-~ ~N~

494 o Cyclopropanecarboxamide, N-(1-~ methylethyl )-N-[(2E,6Z)-2,6-A dodecadienyl]-N' Y/

495 0 Cyclopropanecarboxamide, N-(1,1-~ dimethylethyl)-N-[(2E,6Z)-2,6-~ dodecadienyl]-N' Y/

496 ~ Cyclopropanecarboxamide, N-ethenyl-N-[(2E,6Z)-2,6-dodecadienyl]-N
J

497 , 0 Cyclopropanecarboxamide, N-~ [(2E,6Z)-2,6-dodecadienyl]-N-(2-~ propenyl)-N~

498 o Cyclopropanecarboxamide, N-~ ~ (cyclopropylmethyl)-N-[(2E,6Z)-2,6-N' Y/ dodecadienyl]-Compound # Structure (Novel compounds)CA Index Name 499 O Cyclopropanecarboxamide, N-butyl-N-\ ~ [(2E,6Z)-2,6-dodecadienyl]-N

500 O Cyclopropanecarboxamide, N-~ ~ [(2E,6Z)-2,6-dodecadienyl]-N-(2-N' Y/ methylpropyl)-501 Cyclopropanecarboxamide, N-[(2Z,6Z)-2,6-dodecadienyl]-N-O methyl-N
V

50~ Cyclopropanecarboxamide, N-[(2Z,6Z)-2,6-dodecadienyl]-N-ethyl-N

503 Cyclopropanecarboxamide, N-[(2Z,6Z)-2,6-dodecadienyl]-N-O propyl_ N

504 Cyclopropanecarboxamide, N-(1-methylethyl )-N-[(2Z,6Z)-2,6-O dodecadienyl]-N

505 Cyclopropanecarboxamide, N-(l,l-dimethylethyl)-N-[(2Z,6Z)-2,6-O dodecadienyl]-N

506 Cyclopropanecarboxamide, N-ethenyl-N-((2Z,6Z)-2,6-dodecadienyl]-O

N
VJ

Compound # Structure (Novel compounds) CA Index Name 507 Cyclopropanecarboxamide, N-[(2Z,6Z)-2,6-dodecadienyl]-N-(2-0 propenyl)-N
508 V Cyciopropanecarboxamide, N-(cyclopropylmethyl)-N-[(2Z,6Z)-2,6-O dodecadienylJ-N
Vd 509 /~/~ Cyclopropanecarboxamide, N-butyl-N-[(2Z,6Z)-2,6-dodecadienyl]-O
N
510 Cyclopropanecarboxamide, N-[(2Z,6Z)-2,6-dodecadienyl]-N-(2-O methylpropyl)-N
511 Cyclopropanecarboxamide, N-[(2E)-3-N (4-methyl-3-cyclohexen-1-yl)-2-butenyl]-N-methyl-512 ~ Cyclopropanecarboxamide, N-[(2E)-3-(4-methyl-3-cyclohexen-1-yl)-2-butenyl]-N-ethyl-513 o Cyclopropanecarboxamide, N-[(2E)-3-(4-methyl-3-cyclohexen-1-yl)-2-butenyl]-N-propyl-514 Cyclopropanecarboxamide, N-[(2E)-3-(4-methyl-3-cyclohexen-1-yl)-2-butenylJ-N-(1-methylethy1)-515 o Cyclopropanecarboxamide, N-[(2E)-3-N (4-methyl-3-cyclohexen-1-yl)-2-butenylJ-N-(1,1-dimethylethyl)-516 0 Cyclopropanecarboxamide, N-[(2E)-3-N (4-methyl-3-cyclohexen-1-yl)-2-butenylJ-N-ethenyl-Compound # Structure (Novel compounds) CA Index Name 517 ~ Cyclopropanecarboxamide, N-[(2E)-3-N (4-methyl-3-cyclohexen-1-yl)-2-butenyl]-N-(2-propenyl)-N-[(2E)-3-518 Cyclopropanecarboxamide, N (4-methyl-3-cyclohexen-1-yl)-2 butenyl]-N-(cyclopropylmethyl) 519 Cyclopropanecarboxamide, N-[(2E)-3 N (4-methyl-3-cyclohexen-1-yl)-2-butenyl]-N-butyl-52G Cyclopropanecarboxamide, N-[(2E)-3-N (4-methyl-3-cyclohexen-1-yl)-2-butenyl]-N-(2-methylpropyl)-521 Cyclopropanecarboxamide, N-[(2Z)-3-(4-methyl-3-cyclohexen-1-yl)-2-butenyl]-N-methyl-N
[[//~
522 Cyclopropanecarboxamide, N-[(2Z)-3 (4-methyl-3-cyclohexen-1-yl)-2-butenyl]-N-ethyl-N
523 [/ Cyclopropanecarboxamide, N-[(2Z)-3-(4-methyl-3-cyclohexen-1-yl)-2-butenyl]-N-propyl- i N
524 Cyclopropanecarboxamide, N-[(2Z)-3-(4-methyl-3-cyclohexen-1-yl)-2-butenyl]-N-(1-methylethy1)-N
525 V Cyclopropanecarboxamide, N-[(2Z)-3-(4-methyl-3-cyclohexen-1-yl)-2-butenyl]-N-(1,1-dimethylethyl)-N T/

Compound # Structure (Novel compounds)CA Index Name 526 Cyclopropanecarboxamide, N-[(2Z)-3-(4-methyl-3-cyclohexen-1-yl)-2-butenyl]-N-ethenyl-N
//

[[
J

527 Cyclopropanecarboxamide, N-[(2Z)-3-(4-methyl-3-cyclohexen-1-yl)-2-butenyl]-N-(2-propenyl)-\ N
VV

528 Cyclopropanecarboxamide, N-[(2Z)-3-w (4-methyl-3-cyclohexen-1-yl)-2-butenyl]-N-(cyclopropylmethyl)-\ N

529 Cyclopropanecarboxamide, N-[(2Z)-3-w (4-methyl-3-cyclohexen-1-yl)-2-butenyl]-N-butyl-\ N
~

530 Cyclopropanecarboxamide, N-[(2Z)-3-w (4-methyl-3-cyclohexen-1-yl)-2-butenyl]-N-(2-methylpropyl)-\ N
V

531 Cyclopropanecarboxamide, N-(3-N methyl-2-butenyl)-N-methyl-I

532 Cyclopropanecarboxamide, N-(3-N methyl-2-butenyl)-N-ethyl-533 Cyclopropanecarboxamide, N-(3-N methyl-2-butenyl)-N-propyl-534 Cyclopropanecarboxamide, N-(3-N methyl-2-butenyl)-N-(1-methylethyl)-535 Cyclopropanecarboxamide, N-(3-N methyl-2-butenyl)-N-(1,1-dlmethylethyl)-Compound # Structure (Novel compounds)CA Index Name 536 Cyclopropanecarboxamide, N-(3-methyl-2-butenyl)-N-ethenyl-537 Cyclopropanecarboxamide, N-(3-methyl-2-butenyl)-N-(2-propenyl)-538 Cyclopropanecarboxamide, N-(3-methyl-2-butenyl)-N-(cyclopropylmethyl)-539 Cyclopropanecarboxamide, N-(~-methyl-2-butenyl)-N-butyl-540 Cyclopropanecarboxamide, N-(3-methyl-2-butenyl)-N-(2-methylpropyl)-541 o Cyclopropanecarboxamide, N-methyl-N-[(2E)-3-(2,4-dimethyl-3-cyclohexen-1-yl)-2-propenyl]-542 o Cyclopropanecarboxamide, N-ethyl-N-[(2E)-3-(2,4-dimethyl-3-cyclohexen-1-yl)-2-propenyl]-543 Cyclopropanecarboxamide, N-[(2E)-(2,4-dimethyl-3-cyclohexen-1-yl)-2-propenyl]-N-propyl-544 o Cyciopropanecarboxamide, N-(i-methylethyl)-N-[(2E)-3-(2,4-dimethyl-3-cyclohexen-1-yl)-2-propenyl]-545 Cyclopropanecarboxamide, N-(l,l-methylethyl)-N-[(2E)-3-(2,9-dimethyl-3-cyclohexen-1-yl)-2-propenyl]-546 Cyclopropanecarboxamide, N-ethenyl-N-[(2E)-3-(2,4-dimethyl-3-cyclohexen-1-yl)-2-propenyl]-Cyclopropanecarboxamide, N-[(2E)-3-(2,4-dimethyl-3-cyclohexen-1-yl)-2-propenyl]-N-(2-propenyl)-Compound # Structure (Novel compounds) CA Index Name 548 ~ Cyclopropanecarboxamide, N-N (cyclopropylmethyl)-N-[(2E)-3-(2,4-dimethyl-3-cyclohexen-1-yl)-2-propenyl]-549 ° Cyclopropanecarboxamide, N-butyl-N
N [(2E)-3-(2,4-dimethyl-3-cyclohexen 1-yl)-2-propenyl]
550 o Cyclopropanecarboxamide, N-[(2E)-3 N (2,4-dimethyl-3-cyclohexen-1-yl)-2 propenyl]-N-(2-methylpropyl) 551 Cyclopropanecarboxamide, N-methyl-i N-[(2Z)-3-(2,4-dimethyl-3-cyclohexen-1-yl)-2-propenyl]-N
[[//~
552 Cyclopropanecarboxamide, N-ethyl-N
i [(2Z)-3-(2,4-dimethyl-3-cyclohexen-1-yl)-2-propenyl]-0I' N
553 Cyclopropanecarboxamide, N-[(2Z)-3-i (2,4-dimethyl-3-cyclohexen-1-yl)-2-propenyl]-N-propyl-N T/
V
554 Cyclopropanecarboxamide, N-(1 i methylethyl)-N-[(2Z)-3-(2,4-dimethyl-3-cyclohexen-1-yl)-2-propenyl]-N
555 Cyclopropanecarboxamide, N-(l,l-i methylethyl)-N-[(2Z)-3-(2,4-dimethyl-3-cyclohexen-1-yl)-2-propenyl]-N
556 Cyclopropanecarboxamide, N-ethenyl-i N-[(22)-3-(2,4-dimethyl-3-cyclohexen-1-yl)-2-propenyl]-N
[[//J

Compound # Structure (Novel compounds)CA Index Name 557 Cyclopropanecarboxamide, N-[(2Z)-3-r (2,4-dimethyl-3-cyclohexen-1-yl)-2-propenyl]-N-(2-propenyl)-\ N

558 Cyclopropanecarboxamide, N-r (cyclopropylmethyl)-N-[(2Z)-3-(2,4-dimethyl-3-cyclohexen-1-yl)-2-propenyl]-\ N

559 Cyclopropanecarboxamide, N-butyl-N-r [(2Z)-3-(2,9-dimethyl-3-cyclohexen-1-yl)-2-propenyl]-\ N

560 Cyclopropanecarboxamide, N-[(2Z)-3-r (2,9-dimethyi-3-cyclohexen-1-yl)-2-propenyl]-N-(2-methylpropyl)-561 Acetamide, N-[(2E)-3-(4-methyl-3-N cyclohexen-1-yl)-2-butenyl]-N-methyl-562 II Acetamide, N-[(2E)-3-(4-methyl-3-~

N cyclohexen-1-yl)-2-butenyl]-N-ethyl-563 ~ II Acetamide, N-[(2E)-3-(4-methyl-3-~

N cyclohexen-1-yl)-2-butenyl]-N-propyl-564 II Acetamide, N-[(2E)-3-(4-methyl-3-~

N cyclohexen-1-yl)-2-butenyl]-N-(1-methylethyl)-565 I' Acetamide, N-[(2E)-3-(4-methyl-3-~

N cyclohexen-1-yl)-2-butenyl]-N-(1,1-~ dimethylethyl)-566 II Acetamide, N-[(2E)-3-(4-methyl-3-~

N cyclohexen-1-yl)-2-butenyl]-N-ethenyl-Compound # Structure (Novel compounds)CA Index Name 567 II Acetamide, N-[(2E)-3-(4-methyl-3-~

N cyclohexen-1-yl)-2-butenyl]-N-(2-propenyl)-568 Acetamide, N-[(2E)-3-(4-methyl-3-~

N cyclohexen-1-yl)-2-butenyl]-N-(cyclopropylmethyl)-569 Acetamide, N-[(2E)-3-(4-methyl-3-~ l N cyc ohexen-1-yl)-2-butenyl]-N-butyl-570 II Acetamide, N-[(2E)-3-(4-methyl-3-~

N cyclohexen-1-yl)-2-butenyl]-N-(2-methylpropyl)-571 Acetamide, N-[(2Z)-3-(4-methyl-3-cyclohexen-1-yl)-2-butenyl]-N-methyl-N

572 Acetamide, N-[(2Z)-3-(4-methyl-3-cyclohexen-1-yl)-2-butenyl]-N-ethyl-N

573 Acetamide, N-[(2Z)-3-(4-methyl-3-cyclohexen-i-yl)-2-butenyl]-N-propyl-o N

579 Acetamide, N-[(2Z)-3-(4-methyl-3-w cyclohexen-1-yl)-2-butenyl]-N-(1-methylethyl)-N

575 Acetamide, N-[(2Z)-3-(4-methyl-3-cyclohexen-1-yl)-2-butenyl]-N-(1,1-dimethylethyl)-N

Compound # Structure (Novel compounds)CA Index Name 576 Acetamide, N-[(2Z)-3-(9-methyl-3-cyclohexen-1-yl)-2-butenyl]-N-ethenyl-\ N

577 Acetamide, N-[(2Z)-3-(4-methyl-3-cyclohexen-1-yl)-2-butenyl]-N-(2-propenyl)-\ N

578 - Acetamide, N-[(2Z)-3-(9-methyl-3-cyclohexen-1-yl)-2-butenyl]-N-(cyclopropylmethyl)-\ N

579 Acetamide, N-[(2Z)-3-(4-methyl-3-cyclohexen-1-yl)-2-butenyl]-N-butyl-\ N

580 Acetamide, N-[(2Z)-3-(9-methyl-3-cyclohexen-1-yl)-2-butenyl]-N-(2-methylpropyl)-\ N

581 oII Acetamide, N-methyl-N-((2E)-3-(2,4-~

N dimethyl-3-cyclohexen-1-yl)-2-I propenyl]-582 II Acetamide, N-ethyl-N-[(2E)-3-(2,4-~

N dimethyl-3-cyclohexen-1-yl)-2-propenyl]-583 oII Acetamide, N-[(2E)-3-(2,9-dimethyl-~

N 3-cyclohexen-1-yl)-2-propenyl]-N-propyl-584 II Acetamide, N-(1-methylethyl)-N-~

N [(2E)-3-(2,4-dimethyl-3-cyclohexen-1-yl)-2-propenyl]-Compound # Structure (Novel compounds) CA Index Name 585 Acetamide, N-(1,1-dimethylethyl)-N-[(2E)-3-(2,4-dimethyl-3-cyclohexen-1-yl)-2-propenyl]-586 Acetamide, N-ethenyl-N-[(2E)-3-(2,4-dimethyl-3-cyclohexen-1-yl)-2-propenyl]-587 II Acetamide, N-[(2E)-3-(2,4-dimethyl-~

N 3-cyclohexen-1-yl)-2-propenyl]-N-(2-propenyl)-588 II Acetamide, N-(cyclopropylmethyl)-N-~

N [(2E)-3-(2,4-dimethyl-3-cyclohexen-1-yl)-2-propenyl]-589 II Acetamide, N-butyl-N-[(2E)-3-(2,4-~

N dimethyl-3-cyclohexen-1-yl)-2-propenyl]-o Acetamide, N-[(2E)-3-(2,4-dimethyl-590 ~
~

N 3-cyclohexen-1-yl)-2-propenyl]-N-(2-methylpropyl)-591 ~ Acetamide, N-methyl-N-[(2Z)-3-(2,4-dimethyl-3-cyclohexen-1-yl)-2-propenyl]-N

592 ~ Acetamide, N-ethyl-N-[(2Z)-3-(2,4-i dimethyl-3-cyclohexen-1-yl)-2-propenyl]-N ' J

593 Acetamide, N-[(2Z)-3-(2,4-dimethyl-i 3-cyclohexen-1-yl)-2-propenyl]-N-propyl-N- \

594 ~ Acetamide, N-(1-methylethyl)-N-i [(2Z)-3-(2,4-dimethyl-3-cyclohexen-1-yl)-2-propenyl]-N

17g Compound # Structure (Novel compounds)CA Index Name 595 Acetamide, N-(l,l-dimethylethyl)-N-i [(2Z)-3-(2,4-dimethyl-3-cyclohexen-1-yl)-2-propenyl]-N \

596 ' Acetamide, N-ethenyl-N-[(2Z)-3-i (2,4-dimethyl-3-cyclohexen-1-yl)-2-propenyl]-0'' N

J

597 Acetamide, N-[(2Z)-3-(2,4-dimethyl-i 3-cyclohexen-1-yl)-2-propenyl]-N-(2-propenyl)-N

598 Acetamide, N-(cyclopropylmethyl)-N-i [(2Z)-3-(2,4-dimethyl-3-cyclohexen-1-yl)-2-propenyl]-0~I
N

599 Acetamide, N-butyl-N-[(2Z)-3-(2,9-i dimethyl-3-cyclohexen-1-yl)-2-propenyl]-N

600 Acetamide, N-[(2Z)-3-(2,4-dimethyl-3-cyclohexen-1-yl)-2-propenyl]-N-(2-methylpropyl)-601 ~ Propanamide, N-methyl-N-(2,6-N nonadienyl)-602 ~ Propanamide, N-ethyl-N-(2,6-N nonadienyl)-603 ~ Propanamide, N-(2,6-nonadienyl)-N-N propyl-Compound # Structure (Novel compounds)CA Index Name 604 ~ Propanamide, N-(1-methylethyl)-N-N (2,6-nonadienyl)-Propanamide, N-(1,1-dimethylethyl)-N N-(2,6-nonadienyl)-Propanamide, N-ethenyl-N-(2,6-N nonadienyl)-607 ~ Propanamide, N-(2,6-nonadienyl)-N-N (2-propenyl)-608 ~ Propanamide, N-(cyclopropylmethyl)-N N-(2,6-nonadienyl)-Propanamide, N-butyl-N-(2,6-N nonadienyl)-610 ~ Propanamide, N-(2,6-nonadienyl)-N-N (2-methylpropyl)-611 Propanamide, N-methyl-N-(2,6-nonadienyl)-N

612 Propanamide, N-ethyl-N-(2,6-nonadienyl)-N

613 Propanamide, N-(2,6-nonadienyl)-N-propyl-N

614 Propanamide, N-(1-methylethyl)-N-(2,6-nonadienyl)-N

615 Propanamide, N-(1,1-dimethylethyl)-N-(2,6-nonadienyl)-N

Compound # Structure (Novel compounds)CA Index Name 616 Propanamide, N-ethenyl-N-(2,6-nonadienyl)-N
y 617 Propanamide, N-(2,6-nonadienyl)-N-o '\
(2-propenyl)-N

618 Propanamide, N-(cyclopropylmethyl)-~ N-(2,6-nonadienyl)-N

Propanamide, N-butyl-N-(2,6-~o~~ nonadienyl)-N

620 Propanamide, N-(2,6-nonadienyl)-N-o ~ (2-meth 1 ro 1)-Y P PY

N

Acetamide, N-methyl-N-(2,6-N nonadienyl)-o~ Acetamide, N-ethyl-N-(2,6-N nonadienyl)-o Acetamide, N-(2,6-nonadienyl)-N-~ ~ r l-~ p opy 624 ~ Acetamide, N-(1-methylethyl)-N-N (2,6-nonadienyl)-625 ~ Acetamide, N-(1,1-dimethylethyl)-N-N (2,6-nonadienyl)-o~ Acetamide, N-ethenyl-N-(2,6-N nonadienyl)-O

627 ~ Acetamide, N-(2,6-nonadienyl)-N-(2-N propenyl)-Compound # Structure (Novel compounds)CA Index Name 628 ~ Acetamide, N-(cyclopropylmethyl)-N-N (2,6-nonadienyl)-d Acetamide, N-butyl-N-(2,6-N nonadienyl)-v 630 ~ Acetamide, N-(2,6-nonadienyl)-N-(2-N methylpropyl)-631 Acetamide, N-methyl-N-(2,6-nonadienyl)-N

632 Acetamide, N-ethyl-N-(2,6-nonadienyi)-N

633 Acetamide, N-(2,6-nonadienyl)-N-propyl_ N

634 Acetamide, N-(1-methylethyl)-N-o~
(2,6-nonadienyl)-N

635 Acetamide, N-(1,1-dimethylethyl)-N-o~
(2,6-nonadienyl)-N

636 Acetamide, N-ethenyl-N-(2,6-nonadienyl)-N

637 Acetamide, N-(2,6-nonadienyl)-N-(2-propenyl)-N

638 Acetamide, N-(cyclopropylmethyl)-N-(2,6-nonadienyl)-N

Compound # Structure (Novel compounds)CA Index Name 639 Acetamide, N-butyl-N-(2,6-nonadienyl)-N

640 Acetamide, N-(2,6-nonadienyl)-N-(2-~ methylpropyl)-N

641 ~ Cyclopropanecarboxamide, N-[[2-N [(3Z)_3_ hexenyl]cyclopropyl]methyll-N-methyl-642 ~ Cyclopropanecarboxamide, N-ethyl-N-[ (2_ [ (3Z)-g_ N hexenyl]c clo rop 1]meth 1]-Y P Y Y

643 ~ Cyclopropanecarboxamide, N-[[2-N [(3Z)_3_ hexenyl]cyclopropyl]methyl]-N-propyl-644 Cyclopropanecarboxamide, N-(1-N methylethyl)-N-[[2-[(3Z)-3-hexenyl]cyclopropyl]methyl]-645 ~ Cyclopropanecarboxamide, N-(l,i-N dimethylethyl)-N-[[2-[(3Z)-3-hexenyl]cyclopropyl]methyl]-646 ~ Cyclopropanecarboxamide, N-ethenyl-N N-((2-[(3Z)-3-hexenyl]cyclopropyl]methyll-647 Cyclopropanecarboxamide, N-[[2-N [(gZ)_3_ hexenyl]cyclopropyl]methyl]-N-(2-propenyl)-648 ~ Cyclopropanecarboxamide, N-[[2-N [(3Z)_3_ hexenyl]cyclopropyl]methyl]-N-(cyclopropylmethyl)-649 ~ Cyclopropanecarboxamide, N-butyl-N-N [[2_[(3Z)_3_ hexenyl]cyclopropyl]methyl]-650 ~ Cyclopropanecarboxamide, N-[(2-N [(3Z)_3_ hexenyl]cyclopropyl]methyl]-N-(2-methylpropyl)-Compound # Structure (Novel compounds)CA Index Name 651 o Cyclopropanecarboxamide, N-[[2-[(3Z)-3-hexenyl]cyclopropyl]methyl]-N-methyl-652 ~ o Cyclopropanecarboxamide, N-ethyl-N-[[2-[(3Z)-3-hexenyl]cyclopropyl]methyl]-653 Cyclopropanecarboxamide, N-[[2-[ (3Z)-3-hexenyl]cyclopropyl]methyl]-N-propyl-654 p Cyclopropanecarboxamide, N-(1-methylethyl)-N-[[2-[(3Z)-3-hexenyl]cyclopropyl]methyl]-655 Cyclopropanecarboxamide, N-(l,l-dimethylethyl)-N-[[2-[(3Z)-~-hexenyl]cyclopropyl]methyl]-656 o Cyclopropanecarboxamide, N-ethenyl-N-[[2-[(3Z)-3-hexenyl]cyclopropyl]methyl]-657 o Cyclopropanecarboxamide, N-[[2-[(3Z)-3-hexenyl]cyclopropyl]methyl]-N-(2-l propeny )-658 p Cyclopropanecarboxamide, N-[[2-[(3Z)-3-hexenyl]cyclopropyl]methyl]-N-(cyclopropylmethyl)-659 o Cyclopropanecarboxamide, N-butyl-N-[[2-[(3Z)_~_ hexenyl]cyclopropyl]methyl]-660 o Cyclopropanecarboxamide, N-[[2-[(3Z)-3-hexenyl]cyclopropyl]methyl]-N-(2-methylpropyl)-661 Cyclopropanecarboxamide, N-[(2-[3-cyclohexen-1-yl]-cyclopropyl)-l]-N-meth meth y y 662 Cyclopropanecarboxamide, N-ethyl-N-((2-[3- cyclohexen-1-yl]-cyclopropyl)-methyl]-Compound # Structure (Novel compounds)CA Index Name 663 o Cyclopropanecarboxamide, N-[(2-[3-N cyclohexen-1-yl]-cyclopropyl)-methyl]-N-propyl-664 0 ~ Cyclopropanecarboxamide, N-(1-methyl ethyl ) -N- [ ( 2- [ 3-cyclohexen-1-yl]-cyclopropyl)-methyl]-665 Cyclopropanecarboxamide, N-(l,l-dimethylethyl)-N-[(2-[3-cyclohexen-1-yl]-cyclopropyl)-methyl]-666 o Cyclopropanecarboxamide, N-ethenyl-N N-[(2-[3- cyclohexen-1-yl]-cyclopropyl)-methyl]-667 Cyclopropanecarboxamide, N-[(2-[3-N cyclohexen-1-yl]-cyclopropyl)-methyl]-N-(2-propenyl)-668 Cyclopropanecarboxamide, N-[(2-[3-N cyclohexen-1-yl]-cyclopropyl)-methyl]-N-(cyclopropylmethyl)-669 Cyclopropanecarboxamide, N-butyl-N-N [(2-[3-cyclohexen-1-yl]-cyclopropyi)-methyl]-670 Cyclopropanecarboxamide, N-[(2-[3-N cyclohexen-1-yl]-cyclopropyl)-methyl]-N-(2-methylpropyl)-671 w Cyclopropanecarboxamide, N-[(2-[3-cyclohexen-1-yl]-cyclopropyl)-oII methyl]-N-methyl-N

672 ~ Cyclopropanecarboxamide, N-ethyl-N-[(2-[3-cyclohexen-1-yl]-oI' cyclopropyl)-methyl]-N

673 ~ Cyclopropanecarboxamide, N-[(2-[3-cyclohexen-1-yl]-cyclopropyl)-methyl]-N-propyl-N

Compound # Structure (Novel compounds) CA Index Name 674 ~ Cyclopropanecarboxamide, N-(1-methylethyl)-N-[(2-[3-cyclohexen-1-° yl]-cyclopropyl)-methyl]-675 ~ Cyclopropanecarboxamide, N-(l,l-dimethylethyl)-N-[(2-[3-cyclohexen-° 1-yl]-cyclopropyl)-methyl]-N
676 ~ Cyclopropanecarboxamide, N-ethenyl-N-[(2-[3-cyclohexen-1-yl]-° cyclopropyl)-methyl]-Cyclopropanecarboxamide, N-[(2-[3-677 cyclohexen-1-yl]-cyclopropyl)-methyl]-N-(2-propenyl)-~N~
678 ~ Cyclopropanecarboxamide, N-[(2-[3-cyclohexen-1-yl]-cyclopropyl)-° meth 1 -N
y ] -(cyclopropylmethyl)-679 ~ Cyclopropanecarboxamide, N-butyl-N-[(2-[3-cyclohexen-1-yl]-cyclopropyl)-methyl]-N
680 ~ Cyclopropanecarboxamide, N-[(2-[3-cyclohexen-1-yl]-cyclopropyl)-methyl]-N-(2-methylpropyl)-N
681 ° Cyclopropanecarboxamide, N-[(1-i N methyl-2-phenyl-cyclopropyl)-methyl]-N-methyl-682 ° Cyclopropanecarboxamide, N-ethyl-N-N [(1-methyl-2-phenyl-cyclopropyl)-methyl]-Compound # Structure (Novel compounds) CA Index Name Cyclopropanecarboxamide, N-[(1-683 ~ N ~ methyl-2-phenyl-cyclopropyl)-methyl]-N-propyl-684 ° Cyclopropanecarboxamide, N-(1-N methylethyl)-N-[(1-methyl-2-phenyl-cyclopropyl)-methyl]-685 ° Cyclopropanecarboxamide, N-(1,1-N dimethylethyl)-N-[(1-methyl-2-phenyl-cyclopropyl)-methyl]-686 o Cyclopropanecarboxamide, N-ethenyl-N N-[(1-methyl-2-phenyl-cyclopropyl)-methyl]-687 Cyclopropanecarboxamide, N-[(1-N methyl-2-phenyl-cyclopropyl)-methyl]-N-(2-propenyl)-688 Cyclopropanecarboxamide, N-[(1-N methyl-2-phenyl-cyclopropyl)-methyl]-N-(cyclopropylmethyl)-689 o Cyclopropanecarboxamide, N-butyl-N-N~ [(1-methyl-2-phenyl-cyclopropyl)-methyl]-690 o Cyclopropanecarboxamide, N-[(1-N methyl-2-phenyl-cyclopropyl)-methyl]-N-(2-methylpropyl)-691 ~ w Cyclopropanecarboxamide, N-[(1-methyl-2-phenyl-cyclopropyl)-o methyl]-N-methyl-N
VV
692 I w Cyclopropanecarboxamide, N-ethyl-N-[(1-methyl-2-phenyl-cyclopropyl)-oI' methyl]-N
J
693 ~ Cyclopropanecarboxamide, N-[(1-methyl-2-phenyl-cyclopropyl)-o methyl]-N-propyl-N
1g7 Compound # Structure (Novel compounds) CA Index Name 694 ~ Cyclopropanecarboxamide, N-(1-methylethyl)-N-[(1-methyl-2-phenyl-° cyclopropyl)-methyl]-N
695 w Cyclopropanecarboxamide, N-(1,1-dimethylethyl)-N-[(1-methyl-2-° phenyl-cyclopropyl)-methyl]-N
696 ~ ~/ Cyclopropanecarboxamide, N-ethenyl-N-[(1-methyl-2-phenyl-cyclopropyl)-methyl]-N
J
697 ~ w Cyclopropanecarboxamide, N-[(1-methyl-2-phenyl-cyclopropyl)-II methyl]-N-(2-propenyl)-N
i ~ Cyclopropanecarboxamide, N-[(1-methyl-2-phenyl-cyclopropyl)-methyl]-N-(cyclopropylmethyl)-N
b 699 w Cyclopropanecarboxamide, N-butyl-N-[(1-methyl-2-phenyl-cyclopropyl)-methyl]-N
700 w Cyclopropanecarboxamide, N-[(i-methyl-2-phenyl-cyclopropyl)-methyl]-N-(2-methylpropyl)-701 ° - Cyclopropanecarboxamide, N-[(2-i N methyl-2-phenyl-cyclopropyl)-methyl]-N-methyl-702 ° Cyclopropanecarboxamide, N-ethyl-N-N [(2-methyl-2-phenyl-cyclopropyl)-methyl] - j 703 Cyclopropanecarboxamide, N-[(2-N methyl-2-phenyl-cyclopropyl)-methyl]-N-propyl-Compound # Structure (Novel compounds) CA Index Name 704 ° Cyclopropanecarboxamide, N-(1-i N methylethyl)-N-[(2-methyl-2-phenyl-cyclopropyl)-methyl]-705 ° Cyclopropanecarboxamide, N-(l,l-N dimethylethyl)-N-[(2-methyl-2-phenyl-cyclopropyl)-methyl]-706 ° Cyclopropanecarboxamide, N-ethenyl-N N-[(2-methyl-2-phenyl-cyclopropyl)-methyl]-707 o Cyclopropanecarboxamide, N-[(2-i N methyl-2-phenyl-cyclopropyl)-methyl]-N-(2-propenyl)-708 o Cyclopropanecarboxamide, N-[(2-i N methyl-c-phenyl-cyclopropyl)-methyl]-N-(cyclopropylmethyl)-709 ° Cyclopropanecarboxamide, N-butyl-N-N [(2-methyl-2-phenyl-cyclopropyl)-methyl]-710 ° Cyclopropanecarboxamide, N-[(2-N methyl-2-phenyl-cyclopropyl)-methyl]-N-(2-methylpropyl)-711 I ~ Cyclopropanecarboxamide, N-[(2-methyl-2-phenyl-cyclopropyl)-~ , methyl]-N-methyl-N
(/
712 ~ Cyclopropanecarboxamide, N-ethyl-N-[(2-methyl-2-phenyl-cyclopropyl)-methyl]-N
713 ~ Cyclopropanecarboxamide, N-[(2-methyl-2-phenyl-cyclopropyl)-~ , methyl]-N-propyl-N
714 ~ Cyclopropanecarboxamide, N-(1-methylethyl)-N-[(2-methyl-2-phenyl-~° ~, cyclopropyl)-methyl]-N
[/.

Compound # Structure (Novel compounds) CA Index Name 715 ~ Cyclopropanecarboxamide, N-(l,l-dimethylethyl)-N-[(2-methyl-2-phenyl-cyclopropyl)-methyl]-N
716 I w Cyclopropanecarboxamide, N-ethenyl N-[(2-methyl-2-phenyl-cyclopropyl) o methyl]
717 ~ Cyclopropanecarboxamide, N-[(2-methyl-2-phenyl-cyclopropyl)-methyl]-N-(2-propenyl)-N
718 ~ Cyclopropanecarboxamide, N-[(2-methyl-2-phenyl-cyclopropyl)-methyl]-N-(cyclopropylmethyl)-N
719 I ~ Cyclopropanecarboxamide, N-butyl-N-[(2-methyl-2-phenyl-cyclopropyl)-methyl]-~N
720 ~ Cyclopropanecarboxamide, N-[(2-methyl-2-phenyl-cyclopropyl)-~ , methyl]-N-(2-methylpropyl)-N- 1'/
721 °~ Cyclopropanecarboxamide, N-[(i-N methyl-2-[(3Z)-3-hexenyl]-I cyclopropyl)-methyl]-N-methyl-722 °~ Cyclopropanecarboxamide, N-ethyl-N-N [(1-methyl-2-[(3Z)-3-hexenyl]-cyclopropyl)-methyl]-723 °~ Cyclopropanecarboxamide, N-[(1-N methyl-2-[(3Z)-3-hexenyl]-cyclopropyl)-methyl]-N-propyl-o Cyclopropanecarboxamide, N-(1-724 methylethyl)-N-[(1-methyl-2-[(3Z)-N
3-hexenyl]-cyclopropyl)-methyl]-Compound # Structure (Novel compounds)CA Index Name 725 ~ Cyclopropanecarboxamide, N-(1,1-dimethylethyl)-N-[(1-methyl-2-[(3Z)-3-hexenyl]-cyclopropyl)-methyl]-726 ~ Cyclopropanecarboxamide, N-ethenyl-N-[(1-methyl-2-[(3Z)-3-hexenyl]-cyclopropyl)-methyl]-727 Cyclopropanecarboxamide, N-[(1-methyl-2-[(3Z)-3-hexenyl]-cyclopropyl)-methyl]-N-(2-propeny1)-728 Cyclopropanecarboxamide, N-[(i-methyl-2-[(3Z)-3-hexenyl]-cyclopropyl)-methyl]-N-(cyclopropylmethyl)-729 Cyclopropanecarboxamide, N-butyl-N-[(1-methyl-2-[(3Z)-3-hexenyl]-cyclopropyl)-methyl]-730 ~ Cyclopropanecarboxamide, N-[(1-methyl-2-[(3Z)-3-hexenyl]-cyclopropyl)-methyl]-N-(2-methylpropyl)-~

731 0 Cyclopropanecarboxamide, N-[(1-methyl-2-[(3Z)-3-hexenyl]-~

I I cyclopropyi)-methyl]-N-methyl-732 o Cyclopropanecarboxamide, N-ethyl-N-[(1-methyl-2-[(3Z)-3-hexenyl]-cyclopropyl)-methyl]-J

733 ~ o Cyclopropanecarboxamide, N-[(1-methyl-2-[(3Z)-3-hexenyl]-cyclopropyl)-methyl]-N-propyl-734 o Cyclopropanecarboxamide, N-(1-methylethyl)-N-[(1-methyl-2-[(3Z)-3-hexenyl]-cyclopropyl)-methyl]-735 o Cyclopropanecarboxamide, N-(1,1-dimethylethyl)-N-[(1-methyl-2-[(3Z)-3-hexenyl]-cyclopropyl)-methyl]-736 o Cyclopropanecarboxamide, N-ethenyl-N-[(1-methyl-2-[(3Z)-3-hexenyl]-cyclopropyl)-methyl]-Compound # Structure (Novel compounds)CA Index Name 737 Cyclopropanecarboxamide, N-[(1-methyl-2-[(3Z)-3-hexenyl]-cyclopropyl)-methyl]-N-(2-propeny1)-738 Cyclopropanecarboxamide, N-[(1-methyl-2-[(3Z)-3-hexenyll_-cyclopropyl)-methyl]-N-(cyclopropylmethyl)-739 o Cyclopropanecarboxamide, N-butyl-N-[(1-methyl-2-[(3Z)-3-hexenyl]-cyclopropyl)-methyl]-740 o Cyclopropanecarboxamide, N-[(1-methyl-2-[(32)-3-hexenyl]-cyclopropyl)-methyl]-N-(2-methylpropyl)-741 o Cyclopropanecarboxamide, N-[(2-i N phenyl-cyclopropyl)-methyl]-N-methyl-742 Cyclopropanecarboxamide, N-ethyl-N-[(2-phenyl-cyclopropyl)-methyl]-743 Cyclopropanecarboxamide, N-[(2-i N phenyl-cyclopropyl)-methyl]-N-propyl-744 Cyclopropanecarboxamide, N-(1-methylethyl)-N-[(2-phenyl-cyclopropyl)-methyl]-745 Cyclopropanecarboxamide, N-(l,l-dimethylethyl)-N-[(2-phenyl-cyclopropyl)-methyl]-746 Cyclopropanecarboxamide, N-ethenyl-i N N-[(2-methyl-2-phenyl-cyclopropyl)-methyl]-747 o Cyclopropanecarboxamide, N-[(2-phenyl-cyclopropyl)-methyl]-N-(2-propenyl)-748 Cyclopropanecarboxamide, N-[(2-phenyl-cyclopropyl)-methyl]-N-(cyclopropylmethyl)-Compound # Structure (Novel compounds) CA Index Name 749 ° Cyclopropanecarboxamide, N-butyl-N-N ((2-phenyl-cyclopropyl)-methyl]-w 750 o Cyclopropanecarboxamide, N-[(2-N phenyl-cyclopropyl)-methyl]-N-(2-methylpropyl)-751 ~ Cyclopropanecarboxamide, N-((2-phenyl-cyclopropyl)-methyl]-N-methyl-N
752 ~ Cyclopropanecarboxamide, N-ethyl-N-[(2-phenyl-cyclopropyl)-methyl]-N- 1'/
753 I w Cyclopropanecarboxamide, N-[(2-phenyl-cyclopropyl)-methyl]-N-propyi-N
754 /~ Cyclopropanecarboxamide, N-(1-methylethyl)-N-[(2-phenyl-cyclopropyl)-methyl]-N
755 ~ Cyclopropanecarboxamide, N-(1,1-dimethylethyl)-N-[(2-phenyl-cyclopropyl)-methyl]-N
756 ~ Cyclopropanecarboxamide, N-ethenyl-N-[(2-methyl-2-phenyl-cyclopropyl)-methyl]-N
757 - ~ Cyclopropanecarboxamide, N-[(2-phenyl-cyclopropyl)-methyl]-N-(2-~o ~, propenyl)-N' Y/
758 ~ Cyclopropanecarboxamide, N-[(2-phenyl-cyclopropyl)-methyl]-N-~ A (cyclopropylmethyl)-N _ Y/

Compound # Structure (Novel compounds)CA Index Name 759 ~ Cyclopropanecarboxamide, N-butyl-N-I ~I [(2-phenyl-cyclopropyl)-methyl]-N- 1'/

760 w Cyclopropanecarboxamide, N-[(2-phenyl-cyclopropyl)-methyl]-N-(2-methylpropyl)-N T/

761 o Propanamide, N-((2-methyl-2-[4-N~ methyl-3-pentenyl]-cyclopropyl)-I I' methyl]-N-methyl-2,2-dimethyl-762 Propanamide, N-ethyl-N-[(2-methyl-2-[4-methyl-3-pentenyl]-cyclopropyl)-methyl]-2,2-dimethyl-763 Propanamide, N-((2-methyl-2-[4-N methyl-3-pentenyl]-cyclopropyl)-methyl]-N-propyl-2,2-dimethyl-764 Propanamide, N-(1-methylethyl)-N-N [(2-methyl-2-[4-methyl-3-pentenyl]-cyclopropyl)-methyl]-2,2-dimethyl-765 Propanamide, N-(1,1-dimethylethyl)-N-[(2-methyl-2-(4-methyl-3-pentenyl]-cyclopropyl)-methyl]-2,2-dimethyl-766 Propanamide, N-ethenyl-N-[(2-methyl-2-[4-methyl-3-pentenyl]-cyclopropyl)-methyl]-2,2-dimethyl-767 o Propanamide, N-[(2-methyl-2-[9-N methyl-3-pentenyl]-cyclopropyl)-methyl]-N-(2-propenyl)-2,2-dimethyl-768 Propanamide, N-[(2-methyl-2-[4-N methyl-3-pentenyl]-cyclopropyl)-methyl]-N-(cyclopropylmethyl)-2,2-dimethyl-769 Propanamide, N-butyl-N-[(2-methyl-2-[4-methyl-3-pentenyl]-cyclopropyl)-methyl]-2,2-dimethyl-Compound # Structure (Novel compounds) CA Index Name 770 Propanamide, N-[(2-methyl-2-[a-N methyl-3-pentenyl]-cyclopropyl)-methyl]-N-(2-methylpropyl)-2,2-dimethyl-771 Propanamide, N-[(2-methyl-2-[4-o methyl-3-pentenyl]-cyclopropyl)-methyll-N-methyl-2,2-dimethyl-N
772 Propanamide, N-ethyl-N-[(2-methyl-0 2-[4-methyl-3-pentenyl]-~N cyclopropyl)-methyl]-2,2-dimethyl-773 - Propanamide, N-[(2-methyl-2-(4-methyl-3-pentenyl]-cyclopropyl)-methyl]-N-propyl-2,2-dimethyl-N
774 Propanamide, N-(1-methylethyl)-N-o [(2-methyl-2-[4-methyl-3-pentenyl]-cyclopropyl)-methyl]-2,2-dimethyl-N
775 Propanamide, N-(1,1-dimethylethyl)-o N-[(2-methyl-2-[4-methyl-3-pentenyl]-cyclopropyl)-methyl]-2,2-dimethyl-776 Propanamide, N-ethenyl-N-[(2-o methyl-2-[4-methyl-3-pentenyl]-cyclopropyl)-methyl)-2,2-dimethyl-N
J
777 Propanamide, N-[(2-methyl-2-[4-o methyl-3-pentenylj-cycloprcpyl)-N methyl]-N-(2-propenyl)-2,2-dimethyl-778 Propanamide, N-[(2-methyl-2-[4-o methyl-3-pentenyl]-cyclopropyl)-methyl]-N-(cyclopropylmethyl)-2,2-N
dimethyl-779 - Propanamide, N-butyl-N-[(2-methyl-0 2-[4-methyl-3-pentenyl)-~N cyclopropyl)-methyl)-2,2-dimethyl-'' Propanamide, N-[(2-methyl-2-(4-o methyl-3-pentenyl]-cyclopropyl)-methyl]-N-(2-methylpropyl)-2,2-dimethyl-Compound # Structure (Novel compounds)CA Index Name 781 II Butanamide, N-[(2-methyl-2-[4-methyl-3-pentenyl]-cyclopropyl)-I methyl]-N-methyl-782 ~ Butanamide, N-ethyl-N-[(2-methyl-2-[4-methyl-?-pentenyl]-cyclopropyl) methyl]-783 iI Butanamide, N-[(2-methyl-2-[4-methyl-3-pentenyl]-cyclopropyl)-methyl]-N-propy1-789 II Butanamide, N-(1-methylethyl)-N-[(2-methyl-2-[4-methyl-3-pentenyl]-cyclopropyl)-methyl]-785 ~~ Butanamide, N-(l,l-dimethylethyl)-N-[(2-methyl-2-[4-methyl-3-pentenyl]-cyclopropyl)-methyl]-786 I' Butanamide, N-ethenyl-N-[(2-methyl-2-[4-methyl-3-pentenyl]-cyclopropyl)-methy1]-787 Butanamide, N-[(2-methyl-2-[4-methyl-3-pentenyl]-cyclopropyl)-methyl]-N-(2-propenyl)-788 Butanamide, N-[(2-methyl-2-[4-methyl-3-pentenyl]-cyclopropyl)-methyl]-N-(cyclopropylmethyl)-789 Butanamide, N-butyl-N-((2-methyl-2-[4-methyl-3-pentenyl]-cyclopropyl)-methyl]-790 II Butanamide, N-[(2-methyl-2-[4-methyl-3-pentenyl]-cyclopropyl)-methyl]-N-(2-methylpropyl)-791 Butanamide, N-[(2-methyl-2-[4-o methyl-3-pentenyl]-cyclopropyl)-methyl]-N-methyl-I

792 Butanamide, N-ethyl-N-[(2-methyl-2-[4-methyl-3-pentenyl]-cyclopropyl)-methyl]-Compound # Structure (Novel compounds)CA Index Name 793 Butanamide, N-[(2-methyl-2-[4-o methyl-3-pentenyl]-cyclopropyl)-methyl]-N-propyl-794 Butanamide, N-(1-methylethyl)-N-o [(2-methyl-2-[4-methyl-3-pentenyl]-N~ cyclopropyl)-methyl]-Butanamide, N-(1,1-dimethylethyl)-N-[(2-methyl-2-[9-methyl-3-pentenyl]-cyclopropyl)-methyl]-796 Butanamide, N-ethenyl-N-[(2-methyl-0 2-[4-methyl-3-pentenyl)-cyclopropyi)-methyl]-797 Butanamide, N-[(2-methyl-2-[4-o methyl-3-pentenyl]-cyclopropyl)-methyl]-N-(2-propenyl)-798 Butanamide, N-[(2-methyl-2-[4-o methyl-?-pentenyl]-cyclopropyl)-methyl]-N-(cyclopropylmethyl)-799 Butanamide, N-butyl-N-[(2-methyl-2-[4-methyl-3-pentenyl]-cyclopropyl)-methyl]-800 Butanamide, N-[(2-methyl-2-[4-o methyl-3-pentenyl]-cyclopropyl)-methyl]-N-(2-methylpropyl)-801 Propanamide, N-[(1-methyl-2-phenyl-i N cyclopropyl)-methyl]-N-methyl-802 JI Propanamide, N-ethyl-N-[(1-methyl-2-phenyl-cyclopropyl)-methyl]-J

803 ~~ Propanamide, N-[(1-methyl-2-phenyl-cyclopropyl)-methyl]-N-propyl-I

I

Compound # Structure (Novel compounds)CA Index Name 804 II Propanamide, N-(1-methylethyl)-N-~ [(1-meth l-2-hen 1-c clo 1)-N y p y y propy methyl] -805 Propanamide, N-(1,1-dimethylethyl)-~ N-[(1-meth l-2-hen 1)-1-c c1 o N y p y y opr py methyl]-806 ~~ Propanamide, N-ethenyl-N-[(1-i N~ methyl-2-phenyl-cyclopropyl)-methyl]-807 o~~ Propanamide, N-((1-methyl-2-phenyl-~

N cyclopropyl)-methyl)-N-(2-propenyl)-808 oII Propanamide, N-[(1-methyl-2-phenyl--~ clo ro c l)-meth l]-N-N py y p y (cyclopropylmethyl)-809 o Propanamide, N-butyl-N-[(1-methyl-hen 1-c clo ro l)-meth 1]-N p y y p y py 810 Propanamide, N-[(1-methyl-2-phenyl-clo ro c l)-meth l)-N-(2-N p y py y methylpropyl)-811 ~ ~ Propanamide, N-[(1-methyl-2-phenyl-cyclopropyl)-methyl]-N-methyl-N

812 w Propanamide, N-ethyl-N-[(1-methyl-I 2-phenyl-cyclopropyl)-methyl]-N' 813 w Propanamide, N-[(1-methyl-2-phenyl-cyclopropyl)-methyl)-N-propyl-N- "' 814 ~ Propanamide, N-(1-methylethyl)-N-[(1-methyl-2-phenyl-cyclopropyl)-~o J methyl]-N

Compound # Structure (Novel compounds)CA Index Name 815 w Propanamide, N-(l,l-dimethylethyl)-I N-[(1-methyl-2-phenyl-cyclopropyl)-~ ~. methyl]-N

816 w Propanamide, N-ethenyl-N-[(1-I , methyl-2-phenyl-cyclopropyl)-~ / methyl]-N

817 ~ Propanamide, N-[(1-methyl-2-phenyl-I cyclopropyl)-methyl]-N-(2-propenyl)-N

818 ~ Propanamide, N-[(1-methyl-2-phenyl-cyclopropyl)-methyl]-N-~oI' / (cyclopropylmethyl)-N

819 w Propanamide, N-butyl-N-[(1-methyl--I ~ 2-phenyl-cyclopropyl)-methyl]-N

820 w Propanamide, N-[(1-methyl-2-phenyl-I , cyclopropyl)-methyl]-N-(2-methylpropyl)-N

821 ~~ Propanamide, N-[(2-methyl-2-phenyi-cyclopropyl)-methyl]-N-methyl-822 Propanamide, N-ethyl-N-[(2-methyl-i N 2-phenyl-cyclopropyl)-methyl]-I

823 II Propanamide, N-[(2-methyl-2-phenyl-~ ro l)-meth clo l]-N-ro c i py N y p p y py I w 824 II Propanamide, N-(1-methylethyl)-N--N~ [(2-methyl-2-phenyl-cyclopropyl)-i I methyl] -Compound # Structure (Novel compounds)CA Index Name 825 Propanamide, N-(1,1-dimethylethyl)-~

N N-[(2-methyl-2-phenyl-cyclopropyl)-methyl]-82 6 I' Propanamide, N-ethenyl-N-[(2-~ m l-2-hen 1-c clo th r l -N p y y p e y opy ) r=- methyl]-827 o~~ Propanamide, N-[(2-methyl-2-phenyl-~ c clo ro l)-meth l]-N-(2-N y p py y propenyl)-828 Propanamide, N-[(2-methyl-2-phenyl-ro l)-meth l]-N-c clo i N y y p py (cyclopropylmethyl)-829 II Propanamide, N-butyl-N-[(2-methyl-~ l-h l l)-th l -N p eny cyc opropy me y ]

w 830 II Pro,panamide, N-[(2-methyl-2-phenyl-~ c clo ro l)-meth l]-N-(2-N y p py y methylpropyl)-831 w Propanamide, N-[(2-methyl-2-phenyl-cyciopropyl)-methyl]-N-methyl-N-832 w Propanamide, N-ethyl-N-[(2-methyl-I ~I 2-phenyl-cyclopropyl)-methyl]-N

833 ~ Propanamide, N-[(2-methyl-2-phenyl-cyclopropyl)-methyl]-N-propyl-N- "' 834 ~ Propanamide, N-(1-methylethyl)-N--[(2-methyl-2-phenyl-cyclopropyl)-methyl]-N

zoo Compound # Structure (Novel compounds)CA Index Name 835 ~ Propanamide, N-(1,1-dimethylethyl)-I N-[(2-methyl-2-phenyl-cyclopropyl)-~ / methyl)-N

836 w I Propanamide, N-ethenyl-N-[(2-methyl-2-phenyl-cyclopropyl)-~ / methyl]-N

837 ~ Propanamide, N-[(2-methyl-2-phenyl-cyclopropyl)-methyl]-N-(2-propenyl)-N

838 ~ Propanamide, N-[(2-methyl-2-phenyl-cyclopropyl)-methyl]-N-~ ~ (cyclopropylmethyl)-~

N

839 ~ Propanamide, N-butyl-N-[(2-methyl-2-phenyl-cyclopropyl)-methyl]-N.

840 w Propanamide, N-[(2-methyl-2-phenyl-cyclopropyl)-methyl]-N-(2-~ r methylpropyl)-N

841 II Acetamide, N-[(1-methyl-2-phenyl-~

i N cyclopropyi)-methyl]-N-methyl-~I I

842 ~II Acetamide, N-ethyl-N-[(1-methyl-2-N~ phenyl-cyclopropyl)-methyl]-843 Acetamide, N-[(1-methyl-2-phenyl-N cyclopropyl)-methyl]-N-propyl-844 II Acetamide, N-(1-methylethyl)-N-[(1-N~ methyl-2-phenyl-cyclopropyl)-methyl]-Compound # Structure (Novel compounds)CA Index Name 845 !I Acetamide, N-(1,1-dimethylethyl)-N-~

i ((1-methyl-2-phenyl-cyclopropyl)-N

I methyl] -846 I( Acetamide, N-ethenyl-N-[(1-methyl-~

N 2-phenyl-cyclopropyl)-methyl]-L-_ 847 Acetamide, N-[(1-methyl-2-phenyl-i cyclopropyl)-methyl)-N-(2-N

I propenyl)-848 II Acetamide, N-[(1-methyl-2-phenyl-~ l)-meth clo ro l)-N-c i p N py y y I (cyclopropylmethyl)-849 I1 Acetamide, N-butyl-N-[(1-methyl-2-N~ phenyl-cyclopropyl)-methyl)-850 II Acetamide, N-[(1-methyl-2-phenyl-i cyclopropyl)-methyl]-N-(2-N~

I methylpropyl)-851 ~ Acetamide, N-[(1-methyl-2-phenyl-I cyclopropyl)-methyl]-N-methyl-N- \

852 ~ Acetamide, N-ethyl-N-[(1-methyl-2-I phenyl-cyclopropyl)-methyl)-N

853 ~ Acetamide, N-[(1-methyl-2-phenyl-cyclopropyl)-methyl]-N-propyl-N

854 w Acetamide, N-(1-methylethyl)-N-[(1-methyl-2-phenyl-cyclopropyl)-~ methyl]-N' \

855 ~ Acetamide, N-(1,1-dimethylethyl)-N-[(1-methyl-2-phenyl-cyclopropyl)-methyl]-N

Compound # Structure (Novel compounds) CA Index Name 856 ~ Acetamide, N-ethenyl-N-[(1-methyl-2-phenyl-cyclopropyl)-methyl]-N
857 ~ ~ Acetamide, N-[(1-methyl-2-phenyl-cyclopropyl)-methyl]-N-(2-propenyl)-N
I
858 I ~ Acetamide, N-[(1-methyl-2-phenyl-cyclopropyl)-methyl]-N-(cyclopropylmethyl)-N
859 w IAcetamide, N-butyl-N-[(1-methyl-2-Ilphenyl-cyclopropyl)-methyl]-N
860 w Acetamide, N-[(1-methyl-2-phenyl-cyclopropyl)-methyl]-N-(2-methylpropyl)-N
861 ° Acetamide, N-[(2-methyl-2-phenyl-i N cyclopropyl)-methyl]-N-methyl-w I I
862 ° Acetamide, N-ethyl-N-[(2-methyl-2-i I N~ phenyl-cyclopropyl)-methyll_-863 ° Acetamide, N-[(2-methyl-2-phenyl-N~ cyclopropyl)-methyl)-N-propyl-w 864 Acetamide, N-(1-methylethyl)-N-[(2-i N methyl-2-phenyl-cyclopropyl)-methyl]-865 ° Acetamide, N-(1,1-dimethylethyl)-N-N~ [(2-methyl-2-phenyl-cyclopropyl)-methyl] -866 ~II Acetamide, N-ethenyl-N-[(2-methyl-N~ 2-phenyl-cyclopropyl)-methyl]-Compound # Structure (Novel compounds)CA Index Name 867 o Acetamide, N-[(2-methyl-2-phenyl-i N cyclopropyl)-methyl]-N-(2-propenyl)-868 - ~ Acetamide, N-[(2-methyl-2-phenyl-c clo ro l)-meth l]-N-i y N py y p I (cyclopropylmethyl)-o Acetamide, N-butyl-N-[(2-methyl-2-869 ~ l-c hen clo ro l)-meth l]-~ N p y y p py y v w 8~~ ~ Acetamide, N-[(2-methyl-2-phenyl-i cyclopropyl)-methyl]-N-(2-N

I methylpropyl)-871 ~ Acetamide, N-[(2-methyl-2-phenyl-( cyclopropyl)-methyl]-N-methyl-N

872 ~ Acetamide, N-ethyl-N-[(2-methyl-2-phenyl-cyclopropyl)-methyl]-N

873 ~ Acetamide, N-[(2-methyl-2-phenyl-cyclopropyl)-methyl]-N-propyl-N' \

874 ~ Acetamide, N-(1-methylethyl)-N-[(2-methyl-2-phenyl-cyclopropyl)-methyl]-N

875 ~ Acetamide, N-(1,1-dimethylethyl)-N-I [(2-methyl-2-phenyl-cyclopropyl)-methyl]-N

876 - ~ Acetamide, N-ethenyl-N-[(2-methyl-2-phenyl-cyclopropyl)-methyl]-N

Compound # Structure (Novel compounds) CA Index Name 877 ~ Acetamide, N-[(2-methyl-2-phenyl-cyclopropyl)-methyl]-N-(2-propenyl)-N

Acetamide, N-[(2-methyl-2-phenyl-cyclopropyl)-methyl]-N-o (cyclopropylmethyl)-N

_ b 879 ~ Acetamide, N-butyl-N-[(2-methyl-2-phenyl-cyclopropyl)-methyl]-N-880 ~ Acetamide, N-[(2-methyl-2-phenyl-I cyclopropyl)-methyl]-N-(2-methylpropyl)-N

881 0\1 Acetamide, N-[(1-methyl-2-[(3Z)-3-N hexenyl]-cyclopropyl)-methyl]-N-I methyl-882 ~ Acetamide, N-ethyl-N-[(1-methyl-2-[(3Z)-3-hexenyl]-cyclopropyl)-methyl] -883 / o~ Acetamide, N-[(1-methyl-2-[(3Z)-~-N hexenyl]-cyclopropyl)-methyl]-N-propyl-884 ~ o Acetamide, N-(1-methylethyl)-N-[(1-methyl-2-[(3Z)-3-hexenyl]-cyclopropyl)-methyl)-885 0\\ Acetamide, N-(1,1-dimethylethyl)-N-N [(1-methyl-2-[(3Z)-3-hexenyl]-cyclopropyl)-methyl]-886 0\\ Acetamide, N-ethenyl-N-[(1-methyl-N 2-[(3Z)-3-hexenyl]-cyclopropyl)-methyl]-Compound # Structure (Novel compounds)CA Index Name g8~ ~ Acetamide, N-[(1-methyl-2-[(3Z)-3-hexenyl)-cyclopropyl)-methyl]-N-(2-propeny1)-888 ~ Acetamide, N-[(1-methyl-2-[(3Z)-3-hexenyl]-cyclopropyl)-methyl]-N-(cyclopropylmethyl)-889 ~ Acetamide, N-butyl-N-[(1-methyl-2-[(3Z)-3-hexenyl]-cyclopropyl)-t--~ methyl ] -890 ~ Acetamide, N-[(1-methyl-2-[(3Z)-3-hexenyll__-cyclopropyl)-methyl]-N-(2-methylpropyl)-891 o Acetamide, N-[(1-methyl-2-((3Z)-3-hexenyl)-cyclopropyl)-methyl]-N-I
methyl-892 o Acetamide, N-ethyl-N-[(1-methyl-2-[(3Z)-3-hexenyl7-cyclopropyl)-methyl]-$93 Acetamide, N-((1-methyl-2-[(3Z)-3-hexenyl]-cyclopropyl)-methyll_-N-propyl-894 o Acetamide, N-(1-methylethyl)-N-[(1-methyl-2-[(3Z)-3-hexenyl]-cyclopropyl)-methyl]-895 Acetamide, N-(1,1-dimethylethyl)-N-[(1-methyl-2-[(3Z)-3-hexenyl)-cyclopropyl)-methyl]-896 o Acetamide, N-ethenyl-N-[(1-methyl-2-[(3Z)-3-hexenyl]-cyclopropyl)-methyl]-897 - Acetamide, N-((1-methyl-2-[(3Z)-3-hexenyl]-cyclopropyl)-methyl]-N-(2-propeny1)-898 o Acetamide, N-[(1-methyl-2-[(3Z)-3-hexenyl]-cyclopropyl)-methyl]-N-(cyclopropylmethyl)-Compound # Structure (Novel compounds)CA Index Name 899 o Acetamide, N-butyl-N-[(1-methyl-2-[(3Z)-3-hexenyl]-cyclopropyl)-methyl]-900 I Acetamide, N-[(1-methyl-2-[(3Z)-3-j hexenyl]-cyclopropyl)-methyl]-N-(2-~

N methyipropyl)-901 Propanamide, N-[(2-[3-cyclohexen-1-clo ro l)-meth 1]-c l]-N-th I py y y p y me y 902 ~ Propanamide, N-ethyl-N-[(2-[3-l h l l cyc o exen--y ]-cyc opropyl)-methyl]-903 ~~~ Propanamide, N-[(2-[3-cyclohexen-1-l]-c clo ro l)-meth l]-N-l-w y y p y py propy 904 II Propanamide, N-(1-methylethyl)-N-[(2-[3- cyclohexen-1-yl]-cyclopropyl)-methyll-905 Propanamide, N-(1,1-dimethylethyl)-l N N-[( -[3-cyc ohexen-1-yl]-cyclopropyl)-methyl]-906 o'I Propanamide, N-ethenyl-N-[(2-[3-c clohexen-1-l]-c clo ro 1)-y y py y p methyl]-907 0 ~Propanamide, N-[(1-[3-cyclohexen-h yl]-cyclopropyl)-met yll-N-(2-propenyl)-gOg o Propanamide, N-[(2-[3-cyclohexen-1-yl]-cyclopropyl)-methyl]-N-(cyclopropylmethyl)-gOg ~ Propanamide, N-butyl-N-[(2-[3-l cyclohexen-1-y ]-cyclopropyl)-methyl] -910 ~~~ Propanamide, N-[(2-[3-cyclohexen-1-yl]-cyclopropyl)-methyl]-N-(2-methylpropyl)-Compound # Structure (Novel compounds)CA Index Name 911 ~ Propanamide, N-[(2-[3-cyclohexen-1-yl]-cyclopropyl)-methyl]-N-methyl-N

912 w Propanamide, N-ethyl-N-[(2-[3-cyclohexen-1-yl cyclopropyl)-~o / methyl ) -N

913 w Propanamide, N-[(2-[3-cyclohexen-1-yl)-cyclopropyl)-methyl]-N-propyl-N

914 w Propanamide, N-(1-methylethyl)-N-[(2-[3- cyclohexen-1-yl]-cyclopropyl)-methyl)-N

915 ~ Propanamide, N-(1,1-dimethylethyl)-N-[(2-[3-cyclohexen-1-yl]-cyclopropyl)-methyl]-N

916 w Propanamide, N-ethenyl-N-[(2-[3-cyclohexen-1-yl]-cyclopropyl)-methyl]-N

917 ~ Propanamide, N-((2-[3-cyclohexen-1-yl]-cyclopropyl)-methyl]-N-(2-~ / propenyl)-N

918 ~ Propanamide, N-[(2-[3-cyclohexen-1--yl]-cyclopropyl)-methyl]-N-~ ! (cyclopropylmethyl)-N
b 919 ~ Propanamide, N-butyl-N-[(2-[3-cyclohexen-1-yl]-cyclopropyl)-~ / methyl]-N

Compound # Structure (Novel compounds)CA Index Name 920 ~ Propanamide, N-[(2-[3-cyclohexen-1-yl]-cyclopropyl)-methyl]-N-(2-methylpropyl)-N

921 II Acetamide, N-[(2-[3-cyclohexen-i-~ l]-c clo ro l]-N-meth l)-meth N y w I y p py y y 922 Acetamide, N-ethyl-N-[(2-[3-N cyclohexen-1-yl]-cyclopropyl)-methyl]-923 II Acetamide, N-((2-[3-cyclohexen-1-~ l]-c clo ro l]-N-l)-meth ro N y y py p p y py 924 oII Acetamide, N-(1-methylethyl)-N-[(2-~

N [3- cyclohexen-1-yl]-cyclopropyl)-methyl]-925 II Acetamide, N-(1,1-dimethylethyl)-N-~

N [(2-[3- cyclohexen-1-yl]-cyclopropyl)-methyl]-926 Acetamide, N-ethenyl-N-[(2-[3-cyclohexen--yl]-cyclopropyl)-methyl]-927 o Acetamide, N-[(2-(3-cyclohexenyl]-c clo ro l)-meth l]-N-(2-y p py y propenyl)-928 oII Acetamide, N-[(2-[3-cyclohexenyl]-~

N cyclopropyl)-methyl]-N-(cyclopropylmethyl)-929 ~II Acetamide, N-butyl-N-[(2-[3-~

N cyclohexenyl cyclooctenyl]-cyclopropyl)-methyl]-930 ~II Acetamide, N-[(2-[3-cyclohexenyl]-~

N cyclopropyl)-methyl]-N-(2-methylpropyl)-Compound # Structure (Novel compounds)CA Index Name 931 w Acetamide, N-[(2-[3-cyclohexenyl]-cyclopropyl)-methyl]-N-methyl-N' i 932 ~ Acetamide, N-ethyl-N-[(2-[3-cyclohexenyl]-cyclopropyl)-methyl]-N.

933 ~ Acetamide, N-[(2-[3-cyclohexenyl]-cyclopropyl)-methyl]-N-propyl-N

934 ~ Acetamide, N-(1-methylethyl)-N-[(2-i [3- cyclohexen-1-yl]-cyclopropyl)-~o methyl]-N' \

935 ~ Acetamide, N-(l,l-dimethylethyl)-N-[(2-[3- cyclohexen-1-yl]-cyclopropyl)-methyl]-N

936 w Acetamide, N-ethenyl-N-[(2-[3-cyclohexen-1-yl]-cyclopropyl)-methyl J -N

- ~ Acetamide, N-[(2-[3-cyclohexenyl]-cyclopropyl)-methyl]-N-(2-propenyl)-N

938 w Acetamide, N-[(2-[3-cyclohexenyl]-cyclopropyl)-methyl]-N-(cyclopropylmethyl)-N
b 939 ~ Acetamide, N-butyl-N-[(2-[3-cyclohexenyl cyclooctenyl]-cyclopropyl)-methyl]-N

21~

Compound # Structure (Novel compounds) CA Index Name 940 w Acetamide, N-[(2-[3- cyclohexen-1-yl]-cyclopropyl)-methyl]-N-(2-~ methylpropyl)-N- ' 941 Propanamide, N-((2-[3-N cyclohexenyl]-cyclopropyl)-methyl]-I N-methyl-2,2-dimethyl-942 Propanamide, N-ethyl-N-[(2-[3-cyclohexen-1-yl]-cyclopropyl)-methyl]-2,2-dimethyl-943 o Propanamide, N-[(2-[3-N cyclohexenyl]-cyclopropyl)-methyl]-N-propyl-2,2-dimethyl-944 o Propanamide, N-(1-methylethyl)-N-N [(2-[3- cyclohexen-1-yl cyclopropyl)-methyl]-2,2-dimethyl-945 o Propanamide, N-(l,l-dimethylethyl)-N N-[(2-[3-cyclohexenyl]-cyclopropyl)-methyl]-2,2-dimethyl-946 Propanamide, N-ethenyl-N-[(2-[3-cyclohexen-1-yl]-cyclopropyl)-methyl]-2,2-dimethyl-947 Propanamide, N-[(2-[3-N cyclohexenyl]-cyclopropyl)-methyl]-N-(2-propenyl)-2,2-dimethyl-948 Propanamide, N-[(2-[3-cyclohexenyl]-cyclopropyl)-methyl]-N-(cyclopropylmethyl)-2,2-dimethyl-949 Propanamide, N-butyl-N-[(2-[3-N cyclohexen-1-yl]-cyclopropyl)-methyl]-2,2-dimethyl-950 Propanamide, N-[(2-[3-N cyclohexenyl]-cyclopropyl)-methyl]-N-(2-methylpropyl)-2,2-dimethyl-951 Propanamide, N-[(2-[3-cyclohexenyl]-cyclopropyl)-methyl]-N~ N-methyl-2,2-dimeth 1-I I' y Compound # Structure (Novel compounds) CA Index Name 952 Propanamide, N-ethyl-N-[(2-[3-cyclohexen-1-yl]-cyclopropyl)-N meth 1]-2,2-dimeth 1-Y Y

953 Propanamide, N-[(2-[3-cyclohexenyl cyclocctenyl]-cyclopropyl)-methyl]-N- ro 1-2,2-dimeth 1-P PY Y

954 Propanamide, N-(1-methylethyl)-N-[(2-[3- cyclohexen-1-yl]-N c clo ro 1)-meth 1]-2,2-dimeth Y P PY Y Y

955 Propanamide, N-(1,1-dimethylethyl)-N-[(2-[3-cyclooctenyl]-c clo ro 1 -meth 1 -2 2-dimeth Y P PY ) Y ] . Y

956 Propanamide, N-ethenyl-N-[(2-[3-cyclohexen-1-yl]-cyclopropyl)-methyl]-2,2-dimethyl-Propanamide, N-[(2-[3-cyclohexenyl]-cyclopropyl)-methyl]-N N-(2-propen 1)-2,2-dimeth 1-Y Y

958 Propanamide, N-[(2-[3-cyclohexenyl]-cyclopropyl)-methyl]-N-(cyclopropylmethyl)-2,2-dimethyl-959 Propanamide, N-butyl-N-[(2-[3-cyclohexen-1-yl]-cyclopropyl)-N methyl]-2,2-dimethyl-960 Propanamide, N-[(2-[3-cyclohexenyl]-cyclopropyl)-methyl]-N-(2-methylpropyl)-2,2-dimeth Y

961 Butanamide, N-[(2-methyl-2-[4-methyl-3-pentenyl]-cyclopropyl)-~

I methyl]-N-methyl-2-methyl-962 Butanamide, N-ethyl-N-[(2-methyl-[4-methyl-3-pentenyl]-cyclopropyl)-methyl]-2-methyl-963 Butanamide, N-((2-methyl-2-[4-methyl-3-pentenyl]-cyclopropyl)-methyl]-N-propyl-2-methyl-Compound # Structure (Novel compounds)CA Index Name 964 Butanamide, N-(1-methylethyl)-N-[(2-methyl-2-[4-methyl-3-pentenyl]-cyclopropyl)-methyl]-2-methyl-965 Butanamide, N-(l,l-dimethylethyl)-N-[(2-methyl-2-[4-methyl-3-pentenyl]-cyclopropyl)-methyl]-2-methyl-966 Butanamide, N-ethenyl-N-[(2-methyl-2-[4-methyl-3-pentenyl]-cyclopropyl)-methyl]-2-methyl-967 Butanamide, N-[(2-methyl-2-[4-N methyl-3-pentenyl]-cyclopropyl)-methyl]-N-(2-propenyl)-2-methyl-968 ' Butanamide, N-[(2-methyl-2-[4-N methyl-3-pentenyl]-cyclopropyl)-methyl]-N-(cyclopropylmethyl)-2-methyl-969 Butanamide, N-butyl-N-[(2-methyl-N [4-methyl-3-pentenyl]-cyclopropyl)-methyl]-2-methyl-970 Butanamide, N-[(2-methyl-2-[4-N methyl-3-pentenyl]-cyclopropyl)-methyl]-N-(2-methylpropyl)-2-methyl-Butanamide, N-[(2-methyl-2-[4-methyl-3-pentenyl]-cyclopropyl)-N methyl]-N-methyl-2-methyl-I

972 Butanamide, N-ethyl-N-[(2-methyl-[4-methyl-3-pentenyl]-cyclopropyl)-N methyl]-2-methyl-973 Butanamide, N-[(2-methyl-2-[4-o methyl-3-pentenyl]-cyclopropyl)-N methyl]-N-propyl-2-methyl-974 Butanamide, N-(1-methylethyl)-N-[(2-methyl-2-[4-methyl-3-pentenyl]-cyclopropyl)-methyl]-2-methyl-N

Compound # Structure (Novel compounds)CA Index Name 975 Butanamide, N-(1,1-dimethylethyl)-N-[(2-methyl-2-[4-methyl-3-N pentenyl]-cyclopropyl)-methyl]-2-methyl-976 Butanamide, N-ethenyl-N-[(2-methyi-2-[4-methyl-3-pentenyl]-cyclopropyl)-methyl]-2-methyl-N
i 977 Butanamide, N-[(2-methyl-2-[4-methyl-3-pentenyl]-cyclopropyl)-methyll-N-(2-propenyl)-2-methyl-978 Butanamide, N-[(2-methyl-2-[4-o methyl-3-pentenyl]-cyclopropyl)-~ methyl]-N-(cyclopropylmethyl)-2-N~ methyl-L

979 ' Butanamide, N-butyl-N-((2-methyl-2-[9-methyl-3-pentenyl]-cyclopropyl)-methyll-2-methyl-N

~8~ Butanamide, N-[(2-methyl-2-[4-o methyl-3-pentenyl]-cyclopropyl)-methyl]-N-(2-methylpropyl)-2-methyl-981 o Cyclopropanecarboxamide, N-[(2-N'~ methyl-2-[4-methyl-3-pentenyl]-I V cyclopropyl)-methyl]-N-methyl-982 Cyclopropanecarboxamide, N-ethyl-N-N [(2-methyl-2-[4-methyl-3-pentenyl]-cyclopropyl)-methyl]-983 Cyclopropanecarboxamide, N-[(2-N methyl-2-[4-methyl-3-pentenyl]-cyclopropyl)-methyl]-N-propyl-984 Cyclopropanecarboxamide, N-(1-N methylethyl)-N-[(2-methyl-2-[4-methyl-3-pentenyl]-cyclopropyl)-methyl]-o Cyclopropanecarboxamide, N-(l,l-~ N dimethylethyl)-N-[(2-methyl-2-[4-methyl-3-pentenyl]-cyclopropyl)-methyl]-Compound # Structure (Novel compounds)CA Index Name g86 o Cyclopropanecarboxamide, N-ethenyl-~

N N-[(2-methyl-2-[4-methyl-3-pentenyl]-cyclopropyl)-methyl]-o Cyclopropanecarboxamide, N-[(2-N methyl-2-[4-methyl-3-pentenyl]-cyclopropyl)-methyl]-N-(2-propeny1)-9g8 Cyclopropanecarboxamide, N-[(2-N methyl-2-(4-methyl-3-pentenyl]-cyclopropyl)-methyl]-N-(cyclopropylmethyl)-98G o Cyclopropanecarboxamide, N-butyl-N-N [(2-methyl-2-[4-methyl-3-pentenyl]-cyclopropyl)-methyl]-99G Cyclopropanecarboxamide, N-[(2-N methyl-2-[4-methyl-3-pentenyl]-cyclopropyl)-methyl]-N-(2-methylpropyl)-g91 - Cyclopropanecarboxamide, N-[(2-methyl-2-[4-methyl-3-pentenyl]-cyclopropyl)-methyl]-N-methyl-N

992 Cyclopropanecarboxamide, N-ethyl-N-o [(2-methyl-2-[4-methyl-3-pentenyl]-CN
cyclopropyl)-methyl]-993 Cyclopropanecarboxamide, N-[(2-o methyl-2-(4-methyl-3-pentenyl]-cyclopropyl)-methyl]-N-propyl-~N

994 Cyclopropanecarboxamide, N-(1-p methylethyl)-N-[(2-methyl-2-[4-methyl-3-pentenyl]-cyclopropyl)-N

methyl]-995 Cyclopropanecarboxamide, N-(l,l-o dimethylethyl)-N-[(2-methyl-2-[4-methyl-3-pentenyl]-cyclopropyl)-l methyl]-996 Cyclopropanecarboxamide, N-ethenyl-o N-[(2-methyl-2-[4-methyl-3-pentenyl]-cyclopropyl)-methyl]-N

J

Compound # Structure (Novel compounds)CA Index Name Cyclopropanecarboxamide, N-[(2-o methyl-2-[4-methyl-3-pentenyl]-N cyclopropyl)-methyl]-N-(2-propenyl)-9g8 Cyclopropanecarboxamide, N-[(2-o _3_ Y ._ methyl-2-[4-methyl penten 1 N cyclopropyl)-methyl)-N-(cyclopropylmethyl)-999 Cyclopropanecarboxamide, N-butyl-N-[(2-methyl-2-[4-methyl-3-pentenyl]-cyclopropyl)-methyl]-N

J

1000 Cyclopropanecarboxamide, N-[(2-methyl-2-[4-methyl-3-pentenyl]-cyclopropyl)-methyl]-N-(2-N

methylpropyl)-1001 Propanamide, N-((2-methyl-2-[4-methyl-3-pentenyl]-cyclopropyl)-methyl]-N-methyl-2-methyl-1002 Propanamide, N-ethyl-N-[(2-methyl-N 2-(4-methyl-3-pentenyl]-cyclopropyl)-methyl)-2-methyi-1003 Propanamide, N-[(2-methyl-2-[4-N methyl-3-pentenyl]-cyclopropyl)-methyl)-N-propyl-2-methyl-Propanamide, N-(1-methylethyl)-N-N ((2-methyl-2-[4-methyl-3-pentenyl]-cyclopropyl)-methyl]-2-methyl-7.005 Propanamide, N-(1,1-dimethylethyl)-N-[(2-methyl-2-(9-methyl-3-pentenyl]-cyclopropyl)-methyl]-2-methyl-1006 Propanamide, N-ethenyl-N-[(2-N methyl-2-[4-methyl-3-pentenyl]-cyclopropyl)-methyl]-2-methyl-Propanamide, N-[(2-methyl-2-[4-~ N methyl-3-pentenyl]-cyclopropyl)-methyl]-N-(2-propenyl)-2-methyl-Compound # Structure (Novel compounds)CA Index Name 1008 ~ Propanamide, N-[(2-methyl-2-[4-N methyl-3-pentenyl]-cyclopropyl)-methyl]-N-(cyclopropylmethyl)-2-methyl-1009 Propanamide, N-butyl-N-((2-methyl-N 2-[4-methyl-3-pentenyl]-cyclopropyl)-methyl]-2-methyl-1010 ~ Propanamide, N-[(2-methyl-2-[4-N methyl-3-pentenyl]-cyclopropyl)-methyl]-N-(2-methylpropyl)-2-methyl-1011 Propanamide, N-[(2-methyl-2-[4-o methyl-3-pentenyl]-cyclopropyl)-methyl]-N-methyl-2-methyl-N

1012 Propanamide, N-ethyl-N-[(2-methyl-0 2-[4-methyl-3-pentenyl]-cycloprdpyl)-methyl]-2-methyl-'N
(' 1013 Propanamide, N-[(2-methyl-2-(4-o methyl-3-pentenyl]-cyclopropyl)-N~- methyl]-N-propyl-2-methyl-1014 Propanamide, N-(1-methylethyl)-N-o [(2-methyl-2-[4~methyl-3-pentenyl]-cyclopropyl)-methyl]-2-methyl-1015 Propanamide, N-(l,l-dimethylethyl)-o N-[(2-methyl-2-[4-methyl-3-N pentenyl]-cyclopropyl)-methyl]-2-j methyl-1016 Propanamide, N-ethenyl-N-[(2-o methyl-2-[4-methyl-3-pentenyl]-cyclopropyl)-methyl]-2-methyl-N

J

1017 Propanamide, N-[(2-methyl-2-[4-o methyl-3-pentenyl]-cyclopropyl)-methyl]-N-(2-propenyl)-2-methyl-N

1018 Propanamide, N-[(2-methyl-2-[9-o methyl-3-pentenyl]-cyclopropyl)-methyl]-N-(cyclopropylmethyl)-2-N

methyl-Compound # Structure (Novel compounds)CA Index Name 1019 Propanamide, N-butyl-N-[(2-methyl-0 2-[4-methyl-3-pentenyl]-cyclopropyl)-methyl]-2-methyl-1020 Propanamide, N-[(2-methyl-2-[4-o methyl-3-pentenyl]-cyclopropyl)-methyl]-N-(2-methylpropyl)-2-methyl-1021 II 2-butenamide, N-[(2-methyl-2-[4-methyl-3-pentenyl]-cyclopropyl)-I methyl]-N-methyl-1022 0 2-butenamide, N-ethyl-N-((2-methyl-2-[4-methyl-3-pentenylj-cyclopropyl)-methylj-1023 ~ 2-butenamide, N-[(2-methyl-2-(9-methyl-3-pentenyl]-cyclopropyl)-methyl]-N-propyi-1024 0 2-butenamide, N-(1-methylethyl)-N-[(2-methyl-2-[4-methyl-3-pentenyl]-cyclopropyl)-methyl]-1025 ,I 2-butenamide, N-(l,l-dimethylethyl)-N-[(2-methyl-2-[4-methyl-3-pentenyl]-cyclopropyl)-methyl]-1026 l 2-butenamide, N-ethenyl-N-[(2-methyl-2-[9-methyl-3-pentenyl]-cyclopropyl)-methyl]-1027 II 2-butenamide, N-[(2-methyl-2-(4-~ methyl-3-pentenyl]-cyclopropyl)-methyl]-N-(2-propenyl)-1028 ~~ 2-butenamide, N-[(2-methyl-2-[4-methyl-3-pentenyl]-cyclopropyl)-methyl]-N-(cyclopropylmethyl)-1029 II 2-butenamide, N-butyl-N-[(2-methyl-2-[4-methyl-3-pentenyl]-cyclopropyl)-methyl]-Compound # Structure (Novel compounds)CA Index Name 1030 2-butenamide, N-[(2-methyl-2-[4-methyl-3-pentenyl]-cyclopropyl)-methyl]-N-(2-methylpropyl)-1031 1 2-butenamide, N-[(2-methyl-2-[9-o methyl-3-pentenyl]-cyclopropyl)-~ methyl]-N-methyl-I

1032 2-butenamide, N-ethyl-N-[(2-methyl-0 2-[4-methyl-3-pentenyl]-cyclopropyl)-methyl]-1033 2-butenamide, N-[(2-methyl-2-[4-o methyl-3-pentenyl]-cyclopropyl)-methyl]-N-propyl-1034 2-butenamide, N-(1-methylethyl)-N-o [(2-methyl-2-[4-methyl-3-pentenyl]-cyclopropyl)-methyl]-1035 2-butenamide, N-(1,1-o dimethylethyl)-N-[(2-methyl-2-[4-methyl-3-pentenyl]-cyclopropyl)-methyl]-1036 2-butenamide, N-ethenyl-N-[(2-o methyl-2-[4-methyl-3-pentenyl]-cyclopropyl)-methyl]-J

1037 2-butenamide, N-[(2-methyl-2-[4-a methyl-3-pentenyll-cyclopropyl)-methyl]-N-(2-propenyl)-1038 2-butenamide, N-[(2-methyl-2-[9-o methyl-3-pentenyl]-cyclopropyl)-methyl]-N-(cyclopropylmethyl)-1039 2-butenamide, N-butyl-N-((2-methyl-0 2-[4-methyl-3-pentenyl]-cyclopropyl)-methyl]-1040 2-butenamide, N-[(2-methyl-2-[4-o methyl-3-pentenyl]-cyclopropyl)-methyl]-N-(2-methylpropyl)-Compound # Structure (Novel compounds)CA Index Name 1041 2-butenamide, N-[(2-methyl-2-[4-methyl-3-pentenyl]-cyclopropyl)-I methyl]-N-methyl-3-methyl-1042 2-butenamide, N-ethyl-N-[(2-methyl-2-[4-methyl-3-pentenyl]-cyclopropyl)-methyl]-3-methyl-1043 2-butenamide, N-[(2-methyl-2-[4-methyl-3-pentenyl]-cyclopropyl)-methyl]-N-propyl-3-methyl-1044 ~ ' 2-butenamide, N-(1-methylethyl)-N-[(2-methyl-2-[4-methyl-3-pentenyl]-cyclopropyl)-methyl]-3-methyl-1045 2-butenamide, N-(1,1-dimethylethyl)-N-[(2-methyl-2-[4-methyl-3-pentenyl]-cyclopropyl)-methyl]-3-methyl-1046 2-butenamide, N-ethenyl-N-[(2-methyl-2-[4-methyl-3-pentenyl]-cyclopropyl)-methyl]-3-methyl-1047 2-butenamide, N-[(2-methyl-2-[4-methyl-3-pentenyl]-cyclopropyl)-i methyl]-N-(2-propenyl)-3-methyi-1048 2-butenamide, N-[(2-methyl-2-[4-methyl-3-pentenyl]-cyclopropyl)-methyl]-N-(cyclopropylmethyl)-3-methyl-1049 ' I 2-butenamide, N-butyl-N-[(2-methyl-2-[4-methyl-3-pentenyl]-cyclopropyl)-methyl]-3-methyl-1050 2-butenamide, N-[(2-methyl-2-[4-methyl-3-pentenyl]-cyclopropyl)-methyl]-N-(2-methylpropyl)-3-methyl-1051 2-butenamide, N-[(2-methyl-2-[4-methyl-3-pentenyl]-cyclopropyl)-methyl]-N-methyl-3-methyl-I

1052 2-butenamide, N-ethyl-N-[(2-methyl-0 2-[4-methyl-3-pentenyl]-cyclopropyl)-methyl]-3-methyl-Compound # Structure (Novel compounds)CA Index Name 1053 2-butenamide, N-[(2-methyl-2-[4-o methyl-3-pentenyl]-cyclopropyl)-methyl)-N-propyl-3-methyl-1054 2-butenamide, N-(1-methylethyl)-N-o ((2-methyl-2-[4-methyl-3-penten 1]-~ Y

l cyclopropyl)-methyl]-3-methyl-1055 2-butenamide, N-(1,1-o dimethylethyl)-N-[(2-methyl-2-[4-methyl-3-pentenyl]-cyclopropyl)-methyl]-3-methyl-1056 2-butenamide, N-ethenyl-N-[(2-o methyl-2-(4-methyl-3-pentenyl]-cyclopropyl)-methyl)-3-methyl-J

1057 2-butenamide, N-[(2-methyl-2-[4-o methyl-3-pentenyl]-cyclopropyl)-methyl]-N-(2-propenyl)-3-methyl-1058 2-butenamide, N-[(2-methyl-2-[4-o methyl-3-pentenyl]-cyclopropyl)-methyl]-N-(cyclopropylmethyl)-3-methyl-2-butenamide, N-but 1-N
1059 y -((2-methyl-0 2-[4-methyl-3-pentenyl]-cyclopropyl)-methyl]-3-methyl-1060 2-butenamide, N-[(2-methyl-2-[4-o methyl-3-pentenyl]-cyclopropyl)-methyl]-N-(2-methylpropyl)-3-methyl-1061 0 Cyclopropanecarboxamide, N-[(2-[3Z-~ ~ nonenyl]-cyclopropyl)-methyl]-N-methyl I
[/

1062 ~ Cyclopropanecarboxamide, N-ethyl-N-~ ~ [(2-[3Z-nonenyl]-cyclopropyl)-N' Y/ methyl]-Compound # Structure (Novel compounds)CA Index Name 1063 O Cyclopropanecarboxamide, N-[(2-[3Z-~ nonenyl]-cyclopropyl)-methyl]-N-~ propyl-N' Y/

1064 O Cyclopropanecarboxamide, N-(1-~ methylethyl)-N-[(2-[3Z-nonenyl]-~ cyclopropyl)-methyl]-N' Y/

1065 O Cyclopropanecarboxamide, N-(1,1-~ ~ dimethylethyl)-N-((2-[3Z-nonenyl]-N' Y/ cyclopropyl)-methyl]-1066 O Cyclopropanecarboxamide, N-ethenyl-~ N-[(2-[3Z-nonenyl)-cyclopropyl)-~ methyl]-N~
[/

1067 O Cyclopropanecarboxamide, N-[(2-[3Z-~ ~ nonenyl]-cyclopropyl)-methyl]-N-(2-N' Y/ propenyl)-1068 o Cyclopropanecarboxamide, N-[(2-[3Z-nonenyl]-cyclopropyl)-methyl]-N-N
(cyclopropylmethyl)-1069 O Cyclopropanecarboxamide, N-butyl-N-~ ~ [(2-[3Z-nonenyl]-cyclopropyl)-N' Y/ methyl] -[/ I

1070 o Cyclopropanecarboxamide, N-((2-[3Z-,~ ~ nonenyl]-cyclopropyl)-methyl]-N-(2-N' Y/ methylpropyl)-1071 Cyclopropanecarboxamide, N-[(2-[3Z-nonenyl]-cyclopropyl)-methyl]-N-O methyl N
V

1072 Cyclopropanecarboxamide, N-ethyl-N-[(2-[3Z-nonenyl]-cyclopropyl)-O methyl] -N

Compound # Structure (Novel compounds)CA Index Name 1073 Cyclopropanecarboxamide, N-[(2-[3Z-nonenyl]-cyclopropyl)-methyl]-N-O propyl-N

1074 Cyclopropanecarboxamide, N-(1-methylethyl)-N-[(2-[3Z-nonenyl]-O cyclopropyl)-methyl]-N 'C

1075 Cyclopropanecarboxamide, N-(1,1-dimethylethyl)-N-[(2-[3Z-nonenyl]-O cyclopropyl)-methyll_-N

1076 Cyclopropanecarboxamide, N-ethenyl-N-[(2-[3Z-nonenylJ-cyclopropyl)-O methyl]-N
VJ

1077 Cyclopropanecarboxamide, N-[(2-[3Z-nonenyl]-cyclopropyl)-methyl]-N-(2-O propenyl)-N

1078 Cyclopropanecarboxamide, N-[(2-[3Z-nonenyl]-cyclopropyl)-methyl]-N-O (cyclopropylmethyl)-N 'C

1079 Cyclopropanecarboxamide, N-butyl-N-[(2-[3Z-nonenyl]-cyclopropyl)-O methyl]-N 'C

1080 Cyclopropanecarboxamide, N-[(2-[3Z-nonenyl]-cyclopropyl)-methyl]-N-(2-O methylpropyl)-N

Compound # Structure (Novel compounds) CA Index Name 1081 ° Cyclopropanecarboxamide, N-[(2-N~/ methyl-2-[4-methyl-3-cyclohexen-1-I V yl]-cyclopropyl)-methyl]-N-methyl-1082 o Cyclopropanecarboxamide, N-ethyl-N-N [(2-methyl-2-[4-methyl-3-cyclohexen-1-yl]-cyclopropyl)-methyl]-1083 Cyclopropanecarboxamide, N-((2-N methyl-2-[4-methyl-3-cyclohexen-1 yl]-cyclopropyl)-methyl]-N-propyi 1084 ' ° Cyclopropanecarboxamide, N-(1 N methylethyl)-N-[(2-methyl-2-[4-methyl-3-cyclohexen-1-yl]-cyclopropyl)-methyl]-1085 ° Cyclopropanecarboxamide, N-(i,l-N dimethyiethyl)-N-[(2-methyl-2-[4-methyl-3-cyclohexen-1-yl]-cyclopropyl)-methyl]-Cyclopropanecarboxamide, N-ethenyl-N N-[(2-methyl-2-[4-methyl-3-cyclohexen-1-yl]-cyclopropyl)-methyl]-1087 o Cyclopropanecarboxamide, N-[(2-N methyl-2-[4-methyl-3-cyclohexen-i-yl]-cyclopropyl)-methyl]-N-(2-propenyl)-IO$8 Cyclopropanecarboxamide, N-[(2-N methyl-2-[4-methyl-3-cyclohexen-1-yl]-cyclopropyl)-methyl]-N-(cyciopropylmethyl)-1089 Cyclopropanecarboxamide, N-butyl-N-N [(2-methyl-2-[4-methyl-3-cyclohexen-1-yl]-cyclopropyl)-methyl]-1090 Cyclopropanecarboxamide, N-[(2-N methyl-2-[4-methyl-3-cyclohexen-1-yl]-cyclopropyl)-methyl]-N-(2-methylpropyl)-1091 Cyclopropanecarboxamide, N-[(2-methyl-2-[4-methyl-3-cyclohexen-1-yl]-cyclopropyl)-methyl]-N-methyl-N
I

Compound # Structure (Novel compounds)CA Index Name 1092 Cyclopropanecarboxamide, N-ethyl-N-[(2-methyl-2-[4-methyl-3-cyclohexen-1-yl]-cyclopropyl)-methyl]-1093 Cyclopropanecarboxamide, N-[(2-methyl-2-[4-methyl-3-cyclohexen-1-yl]-cyclopropyl)-methyl]-N-propyl-N

1094 Cyclopropanecarboxamide, N-(1-methylethyl)-N-[(2-methyl-2-[4-methyl-3-cyclohexen-1-yl]-cyclopropyl)-methyl]-1095 ' Cyclopropanecarboxamide, N-(l,l-y dimethylethyl)-N-[(2-methyl-2-[4-methyl-3-cyclohexen-1-yl]-~ ~ cyclopropyl)-methyl]- j N~ I

1096 ~ Cyclopropanecarboxamide, N-ethenyl-w N-[(2-methyl-2-[4-methyl-3-cyclohexen-1-yl]-cyclopropyl)-II methyl]-~N~
~/J

1097 Cyclopropanecarboxamide, N-[(2-methyl-2-[4-methyl-3-cyclohexen-1-yl]-cyclopropyl)-methyl]-N-(2-propenyl)-N

1098 Cyclopropanecarboxamide, N-[(2-methyl-2-[4-methyl-3-cyclohexen-1-yl]-cyclopropyl)-methyl]-N-(cyclopropylmethyl)-N

1099 Cyclopropanecarboxamide, N-butyl-N-[(2-methyl-2-[4-methyl-3-cyclohexen-1-yl]-cyclopropyl)-~ , methyl]-N

Compound # Structure (Novel compounds)CA Index Name 1100 Cyclopropanecarboxamide, N-[(2-methyl-2-[4-methyl-3-cyclohexen-I-yl]-cyclopropyl)-methyl]-N-(2-methylpropyl)-1101 Cyclopropanecarboxamide, N-[(2,2-dimethyl-cyclopropyl)-methyl]-N-methyl-1102 Cyclopropanecarboxamide, N-ethyl-N-[(2,2-dimethyl-cyclopropyl)-methylj-1103 ~ Cyclopropanecarboxamide, N-[(2,2-dimethyl-cyclopropyl)-methyl]-N-propyl-1104 Cyclopropanecarboxamide, N-(1-methylethyl)-N-[(2,2-dimethyl-cyclopropyl)-methyl]-1105 o Cyclopropanecarboxamide, N-(1,1-dimethylethyl)-N-[(2,2-dimethyl-cyclopropyl)-methyl]-1106 Cyclopropanecarboxamide, N-ethenyl-N-[(2,2-dimethyl-cyclopropyl)-methyl]-1107 ~ Cyclopropanecarboxamide, N-{(2,2-dimethyl-cyclopropyl)-methyl]-N-(2-propenyl)-1108 Cyclopropanecarboxamide, N-[(2,2-dimethyl-cyclopropyl)-methyl]-N-(cyclopropylmethyl)-1109 Cyclopropanecarboxamide, N-butyl-N-[(2,2-dimethyl-cyclopropyl)-methyl]-1110 Cyclopropanecarboxamide, N-[(2,2-dimethyl-cyclopropyl)-methyl]-N-(2-methylpropyl)-1111 Cyclopropanecarboxamide, N-[(2-[2,4-dimethyl-3-cyclohexen-I-yl]-cyclopropyl)-methyl]-N-methyl-Compound # Structure (Novel compounds)CA Index Name 1112 Cyclopropanecarboxamide, N-ethyl-N-N [(2-[2,4-dimethyl-3-cyclohexen-1-yl]-propyl)-methyl-Cyclopropanecarboxamide, N-((2-1113 N [2,4-dimethyl-3-cyclohexen-1-yl]-cyclopropyl)-methyl]-N-propyl-1114 Cyclopropanecarboxamide, N-(1-N methylethyl)-N-[(2-[2,4-dimethyl-3-cyclohexen-1-yl]-cyclopropyl)-methyll_-1115 Cyclopropanecarboxamide, N-(l,l-N dimethylethyl)-N-((2-(2,4-dimethyl-3-cyclohexen-1-yl]-cyclopropyl)-methyl]-1116 o Cyclopropanecarboxamide, N-ethenyl-N N-((2-(2,4-dimethyl-3-cyclohexen-1-j yl]- cyclopropyl)-methyl]-1117 Cyclopropanecarboxamide, N-[(2-N [2,9-dimethyl-3-cyclohexen-1-yl]-propyl)-methyl]-N-(2-propenyl)-1118 Cyclopropanecarboxamide, N-[(2-N [2,4-dimethyl-3-cyclohexen-1-yl]-cyclopropyl)-methyl]-N-(cyclopropylmethyl)-1119 Cyclopropanecarboxamide, N-butyl-N-N [(2-[2,4-dimethyl-3-cyclohexen-1-yl]- cyclopropyl)-methyl]-1120 Cyclopropanecarboxamide, N-[(2-N [2,4-dimethyl-3-cyclohexen-1-yl]-cyclopropyl)-methyl]-N-(2-methylpropyl)-1121 Cyclopropanecarboxamide, N-[(2-i [2,4-dimethyl-3-cyclohexen-1-y1]-cyclopropyl)-methyl]-N-methyl-1122 Cyclopropanecarboxamide, N-ethyl-N-i [(2-[2,4-dimethyl-3-cyclohexen-1-yl]-cyclopropyl)-methyl]-~N~

Compound # Structure (Novel compounds)CA Index Name 1123 Cyclopropanecarboxamide, N-[(2-i [2,4-dimethyl-3-cyclohexen-1-yl)-cyclopropyl)-methyl]-N-propyl-N
[/~

1124 Cyclopropanecarboxamide, N-(1-i methylethyl)-N-[(2-[2,4-dimethyl-3-cyclohexen-1-yl]-cyclopropyl)-methyl]-N T/
V

1125 ~ Cyclopropanecarboxamide, N-(i,l-i dimethylethyl)-N-[(2-[2,4-dimethyl-3-cyclohexen-1-yl]-cyclopropy1)-methyl]-N

1126 Cyclopropanecarboxamide, N-ethenyl-i N-[(2-[2,4-dimethyl-3-cyclohexen-1-y1]- cyclopropyl)-methyl]-~N~
[[//J

1127 [ Cyclopropanecarboxamide, N-[(2-i [2,4-dimethyl-3-cyclohexen-2-yl]-cyclopropyl)-methyl]-N-(2-propenyl)-N

1128 Cyclopropanecarboxamide, N-[(2-i [2,4-dimethyl-3-cyclohexen-1-yl]-cyclopropyl)-methyl)-N- I

(cyclopropylmethyl)-N

1129 Cyclopropanecarboxamide, N-butyl-N-i [(2-[2,4-dimethyl-3-cyclohexen-1-y1]- cyclopropyl)-methyl]-~N~

1130 Cyclopropanecarboxamide, N-[(2-i [2,4-dimethyl-3-cyclohexen-1-yl]-cyclopropyl)-methyl]-N-(2-methylpropyl)-N

Compound # Structure (Novel compounds)CA Index Name 1131 Acetamide, N-[(2-methyl-2-[4-N~ methyl-3-cyclohexen-1-yl]-I cyclopropyl)-methyl]-N-methyl-o Acetamide, N-ethyl-N-[(2-methyl-2-1132 N~ [4-methyl-3-cyclohexen-1-yl]-cyclopropyl)-methyl]-1133 fI Acetamide, N-[(2-methyl-2-[4-N~ methyl-3-cyclohexen-1-y1]-cyclopropyl)-methyl]-N-propyl-1134 II Acetamide, N-(1-methylethyl)-N-[(2-N~ methyl-2-[4-methyl-3-cyclohexen-1-yl]-cyclopropyl)-methyl]-o Acetamide, N-(1,1-dimethylethyl)-N-I' [(2-methyl-2-[4-methyl-3-N~

cyclohexen-1-yl]-cyclopropyl)-methyl]-o Acetamide, N-ethenyl-N-[(2-methyl-1136 N~ 2-[4-methyl-3-cyclohexen-1-yl]-cyclopropyl)-methyl]-1137 oII Acetamide, N-[(2-methyl-2-[4-N~ methyl-3-cyclohexen-1-yl]-cyclopropyl)-methyl]-N-(2-propenyl)-o Acetamide, N-((2-methyl-2-[4-1138 N~ methyl-3-cyclohexen-1-yl]-cyclopropyl)-methyl]-N-(cyclopropylmethyl)-1139 ' o~~ Acetamide, N-butyl-N-[(2-methyl-2-N~ [4-methyl-3-cyclohexen-1-yl]-cyclopropyl)-methyl]-o Acetamide, N-[(2-methyl-2-[4-1140 N.~ methyl-3-cyclohexen-1-yl]-cyclopropyl)-methyl]-N-(2-methylpropyl)-1141 Acetamide, N-[(2-methyl-2-[4-methyl-3-cyclohexen-1-yl]-cyclopropyl)-methyl]-N-methyl-N
I

Compound # Structure (Novel compounds)CA Index Name 1142 Acetamide, N-ethyl-N-[(2-methyl-2-w [4-methyl-3-cyclohexen-1-yl]-cyclopropyl)-methyl]-N
J

1143 Acetamide, N-[(2-methyl-2-[4-methyl-3-cyclohexen-1-yl)-cyclopropyl)-methyl]-N-propyl-0I!
N

1144 Acetamide, N-(1-methylethyl)-N-[(2-methyl-2-[4-methyl-3-cyclohexen-1-yl]-cyclopropyl)-methyl]-N

1145 Acetamide, N-(i,l-dimethylethyl)-N-[(2-methyl-2-[4-methyl-3-cyclohexen-1-yl)-cyclopropyl)-methyl)-N
I

1146 Acetamide, N-ethenyl-N-[(2-methyl-w 2-[4-methyl-3-cyclohexen-1-yl]-cyclopropyl)-methyl)-0!I
N
J

1147 Acetamide, N-[(2-methyl-2-[4-w methyl-3-cyclohexen-1-yl)-cyclopropyl)-methyl]-N-(2-II propenyl)-N

1148 Acetamide, N-[(2-methyl-2-[4-methyl-3-cyclohexen-1-yl]-cyclopropyl)-methyl]-N-o (cyclopropylmethyl)-N

Compound # Structure (Novel compounds)CA Index Name 1149 Acetamide, N-butyl-N-[(2-methyl-2-(4-methyl-3-cyclohexen-1-yl]-cyclopropyl)-methyl]-N

1150 Acetamide, N-[(2-methyl-2-[4-methyl-3-cyclohexen-1-yl]-cyclopropyl)-methyl]-N-(2-II methylpropyl)-N

1151 II Acetamide, N-[(2-[2,4-dimethyi-3-~ i h N cyc o exen-1-yl]-cyclopropyl)-methyl]-N-methyl-1152 II Acetamide, N-ethyl-N-[(2-[2,4-~

N dimethyl-3-cyclohexen-1-yl]-cyclopropyl)-methyl]-1153 oII Acetamide, N-[(2-[2,4-dimethyl-3-~ l h N cyc o exen-1-yl]-cyclopropyl)-methyl]-N-propyl-1154 o Acetamide, N-(1-methylethyl)-N-[(2-di [
, -methyl-3-cyclohexen-1-yl]-cyclopropyl)-methyl]-o Acetamide, N-(l,l-dimethylethyl)-N-[( -[
,4-dimethyl-3-cyclohexen-1-yi]-cyclopropyl)-methyl]-1156 ~~~ Acetamide, N-ethenyl-N-[(2-[2,4-~

N dimethyl-3-cyclohexen-1-yl]-cyclopropyl)-methyl]-1157 ~~ Acetamide, N-[(2-[2,4-dimethyl-3-~ l N cyc ohexen-1-yl]-cyclopropyl)-methyl]-N-(2-propenyl)-1158 II Acetamide, N-[(2-[2,4-dimethyl-3-~ h N cyclo exen-1-yl]-cyclopropyl)-methyl]-N-(cyclopropylmethyl)-Compound # Structure (Novel compounds)CA Index Name 1159 I, Acetamide, N-butyl-N-[(2-[2,4-~

N dimethyl-3-cyclohexen-1-yl]-cyclopropyl)-methyl]-1160 ~ Acetamide, N-[(2-[2,4-dimethyl-3-N cyclohexen-1-yl]-cyclopropyl)-methyl]-N-(2-methylpropyl)-2161 Acetamide, N-[(2-[2,4-dimethyl-3-cyclohexen-1-yl]-cyclopropyl)-methyl]-N-methyl-N

1162 Acetamide, N-ethyl-N-[(2-[2,9-i dimethyl-3-cyclohexen-1-yl]-cyclopropyl)-methyl]-N
J

1163 Acetamide, N-[(2-[2,4-dimethyl-3-i cyclohexen-1-yl)-cyclopropyl)-methyl)-N-propyl-j N

1164 Acetamide, N-(1-methylethyl)-N-[(2-i [2,4-dimethyl-3-cyclohexen-1-yl]-cyclopropyl)-methyl]-N

1165 Acetamide, N-(1,1-dimethylethyl)-N-i [(2-[2,4-dimethyl-3-cyclohexen-1-yl]-cyclopropyl)-methyl]-N

1166 Acetamide, N-ethenyl-N-[(2-[2,4-i dimethyl-3-cyclohexen-1-yl]-cyclopropyl)-methyl]-N
J

Compound # Structure (Novel compounds)CA Index Name 1167 ~ Acetamide, N-[(2-[2,4-dimethyl-3-i cyclohexen-1-ylJ-cyclopropyl)-methyl]-N-(2-propenyl)-N

1168 Acetamide, N-((2-[2,4-dimethyl-3-i cyclohexen-1-yl]-cyclopropyl)-methyl]-N-(cyclopropylmethyl)-N

1169 Acetamide, N-butyl-N-[(2-[2,4-i dimethyl-3-cyclohexen-1-yl]-cyclopropyl)-methyl]-N' \

1170 Acetamide, N-[(2-[2,4-dimethyl-3-i cyclohexen-1-yl]-cyclopropyl)-methyl]-N-(2-methylpropyl)-N

1171 Propanamide, N-[(2-[3Z-hexenyl]-N cyclopropyl)-methyl]-N-methyl-1172 ~ Propanamide, N-ethyl-N-[(2-[3Z-N hexenyl]-cyclopropyl)-methylJ-1173 ~ Propanamide, N-[(2-[3Z-hexenyl]-N cyclopropyl)-methyl]-N-propyl-1174 ~ Propanamide, N-(1-methylethyl)-N-N [(2-[3Z-hexenyl]-cyclopropyl)-methyl]-1175 ~ Propanamide, N-(1,1-dimethylethyl)-N N-((2-[3Z-hexenyl]-cyclopropyl)-methyl]-Compound # Structure (Novel compounds) CA Index Name 1176 ~ Propanamide, N-ethenyl-N-[(2-[3Z-N hexenyl]-cyclopropyl)-methyl]-O

1177 ~~ Propanamide, N-[(2-[3Z-hexenyl]-N cyclopropyl)-methyl]-N-(2-propenyl)-1178 ~ Propanamide, N-[(2-[3Z-hexenyl]-N cyclopropyl)-methyl]-N-(cyclopropylmethyl)-1179 ~ Propanamide, N-butyl-N-[(2-[3Z-N hexenyl]-cyclopropyl)-methyl]-1180 ~ Propanamide, N-[(2-[3Z-hexenyl]-N cyclopropyl)-methyl]-N-(2-methylpropyl)-1181 Propanamide, N-[(2-[3Z-hexenyl]-~/ cyclopropyl)-methyl]-N-methyl-N

1182 Propanamide, N-ethyl-N-[(2-[3Z-~/ hexenyl]-cyclopropyl)-methyl]-N

1183 Propanamide, N-[(2-[3Z-hexenyl]-~ cyclopropyl)-methyl]-N-propyl-N
i 1184 Propanamide, N-(1-methylethyl)-N-o ~
-' [(2-[32-hexenyl]-cyclopropyl)-N methyl]-1185 Propanamide, N-(1,1-dimethylethyl)-~/ N-[(2-[3Z-hexenyl]-cyclopropyl)-N methyl]-1186 Propanamide, N-ethenyl-N-[(2-[3Z-~./ hexenyl]-cyclopropyl)-methyl]-N

1187 Propanamide, N-[(2-[3Z-hexenyl]-~/ cyclopropyl)-methyl]-N-(2-N propenyl)-Compound # Structure (Novel compounds)CA Index Name 1188 Propanamide, N-[(2-[3Z-hexenyll-~ cyclopropyl)-methylj-N-(cyclopropylmethyl)-1189 Propanamide, N-butyl-N-[(2-[3Z-hexenyl]-cyciopropyl)-methyl]-N

1190 Propanamide, N-[(2-[3Z-hexenylj-~/ cyclopropyl)-methyl]-N-(2-N methylpropyl)-1191 ~ Acetamide, N-[(2-[3Z-hexenylj-N cycloprcpyl)-methyl)-N-methyl-v 1192 ~ Acetamide, N-ethyl-N-[(2-[3Z-N hexenyl]-cyclopropyl)-methyl]-1193 ~ Acetamide, N-[(2-[3Z-hexenyl)-N cyclopropyl)-methyl)-N-propyl-1194 ~ Acetamide, N-(1-methylethyl)-N-[(2-N [3Z-hexenyl]-cyclopropyl)-methyll_-1195 '~ Acetamide, N-(1,1-dimethylethyl)-N-[(2-[3Z-hexenyl]-cyclopropyl)-methyl]_ 1196 ~ Acetamide, N-ethenyl-N-[(2-[3Z-N hexenyl]-cyclopropyl)-methyl)-1197 ~ Acetamide, N-[(2-(3Z-hexenyl]-N cyclopropyl)-methyl]-N-(2-propenyl)-1198 ~ Acetamide, N-[(2-[3Z-hexenyl]-N cyclopropyl)-methyl]-N-(cyclopropylmethyl)-Compound # Structure (Novel compounds)CA Tndex Name 1199 ~ Acetamide, N-butyl-N-[(2-[3Z-N hexenyl]-cyclopropyl)-methyl]-1200 ~ Acetamide, N-[(2-[3Z-hexenyl]-cyclopropyl)-methyl]-N-(2-methylpropyl)-1201 Acetamide, N-[(2-[3Z-hexenylJ-~. cyclopropyl)-methyl]-N-methyl-N

1202 ~ Acetamide, N-ethyl-N-[(2-[3Z-~ hexenyl]-cyclopropyl)-methyl]-N

1203 Acetamide, N-[(2-[3Z-hexenyl]-c clo ro 1)-meth 1]-N
N Y P pY y -propyl-1204 Acetamide, N-(1-methylethyl)-N-[(2-~ [3Z-hexenyl]-cyclopropyl)-methyl]-N

2205 Acetamide, N-(1,1-dimethylethyl)-N-I

, ~ [(2-(3Z-hexenyl]-cyclopropyl)-N methyl]-1206 Acetamide, N-ethenyl-N-[(2-[3Z-~ hexenyl]-cyclopropyl)-methyl]-N

1207 Acetamide, N-[(2-(3Z-hexenyl]-~ cyclopropyl)-methyl]-N-(2-propenyl)-1208 Acetamide, N-[(2-[3Z-hexenyl]-o~ cyclopropyl)-methyl]-N-(cyclopropylmethyl)-1209 Acetamide, N-butyl-N-[(2-(3Z-~ hexenyl]-cyclopropyl)-methyl]-N

Compound # Structure (Novel compounds) CA Index Name 1210 Acetamide, N-[(2-[3Z-hexenyl]-cyclopropyl)-methyl]-N-(2-methylpropyl)-1211 2-butenamide, N-[(2E)-3,7-dimethyl-2,6-octadienyl]-2-methyl-(2E)-N
H

1212 2-butenamide, N-[(2Z)-3,7-dimethyl-2,6-octadienyl]-2-methyl-(2E)-I H i[ _ 1213 2-butenamide, N-[[2-methyl-2-(4-methyl-3-H pentenyl)cyclopropyl]methyl]-~ o Acetamide, N-[[2-methyl-2-(4-1214 methyl-3-H pentenyl)cyclopropyl]methyl]-Propanamide, N-[[2-methyl-2-(4-~ methyl-3-H pentenyl)cyclopropyl]methylj-1216 Propanamide, N-[[2-methyl-2-(4-N~/ methyl-3-I pentenyl)cyclcpropyl]methyl]-2-methyl-1217 2-methyl-2-(4-methyl-3-pentenyl)Cyclopropanecarboxamide, N-cyclopropyl-1218 c-methyl-2-(4-methyl-3-pentenyl) Cyclopropanecarboxamide, N-2-propenyl-1219 2-methyl-2-(4-methyl-3-pentenyl) Cyclopropanecarboxamide, N-2-methylpropanyl-2-methyl-2-(4-methyl-3-pentenyl) Cyclopropanecarboxamide, N-methyl-1221 2-methyl-2-(4-methyl-3-pentenyl) Cyclopropanecarboxamide, N-ethyl-Compound # Structure (Novel compounds)CA Index Name 1222 ~ 2-methyl-2-(9-methyl-3-pentenyl) Cyclopropanecarboxamide, N-1-methylethyl-1223 0 2-methyl-2-(4-methyl-3-pentenyl) Cyclopropanecarboxamide, N-cyclopropyl-1224 0 2-methyl-2-(4-methyl-3-pentenyl) Cyclopropanecarboxamide, N,N-I dimethyl-We have surprisingly found the literature has not previously reported dienalkylamides, alkenylamides, or cyclopropylic amides as having or enhancing umami flavor. In addition, closely structurally related compounds such as dienals and unsaturated acids, are not specifically reported to possess umami character when tasted in isolation. In addition the ability to provide an enhanced saltiness for the product without increasing sodium level is not disclosed or suggested by the prior art. The salt enhancing properties of the compounds of the present invention are important because it allows flavorists to provide the desired salty taste profile in foods and beverages without actually having higher salt levels in the food.
Therefore the consumer can have both the taste profile that they desire while without having the adverse health effects associated with increased salt levels such as hypertension.
As used herein olfactory effective amount is understood to mean the amount of compound in flavor compositions the individual component will contribute to its particular olfactory characteristics, but the flavor, taste and aroma effect on the overall composition will be the sum of the effects of each of the flavor ingredients. As used herein taste effects include salt, sweet and umami effects. Thus the compounds of the invention can be used to alter the taste characteristics of the flavor composition by modifying the taste reaction contributed by another ingredient in the composition. The amount will vary depending on many factors including other ingredients, their relative amounts and the effect that is desired.
The level of cyclopropylic amides, alkenylamides and dienalkylamides used in products is greater than 50 parts per billion, generally provided at a level of from about 0.01 parts per million to about 50 parts per million in the finished product, more preferably from about 0.1 parts per million to about 20 parts per million by weight, and in preferred embodiments from about 0.5 to about 5 parts per million.
The usage level of cyclopropylic amides, alkenylamides, and dienalkylamides varies depending on the product in which the dienalkylamides are employed. For example, alcoholic beverages the usage level is from about 0.1 to about 5 parts per million, preferably from about 0.5 to about 3 and most preferably from about 1 to about 2 parts per million by weight. Non-alcoholic beverages are flavored at levels of from about 0.05 parts per million to about 5 parts per million, preferably from about 0.1 parts per billion to about 2 parts per million and in highly preferred situations of from about 0.7 to about 1 parts per billion. Other products such as snack foods, candy and gum products can be advantageously flavored using compounds of the present invention at levels described above.
Among the preferred compounds of the present invention are:
2-butenamide, N-[(2E)-3,7-dimethyl-2,6-octadienyl]-, (2E)-2-butenamide, N-[(2Z)-3,7-dimethyl-2,6-octadienyl]-, (2E)-2-butenamide, N-[(2E)-3,7-dimethyl-2,6-octadienyl]-3-methyl-2-butenamide, N-[(2Z)-3,7-dimethyl-2,6-octadienyl]-3-methyl-2-butenamide, N-[(2E)-3,7-dimethyl-2,6-octadienyl]-2-methyl-(2E)-2-butenamide, N-[(2Z)-3,7-dimethyl-2,6-octadienyl]-2-methyl-(2E)-Cyclopropanecarboxamide, N-[(2Z,6Z)-2,6-nonadienyl]-Cyclopropanecarboxamide, N-[(2E,6Z)-2,6-nonadienyl]-Cyclopropanecarboxamide, N-[(2E)-3-(3-cyclohexen-1-yl)-2-propenyl]-Cyclopropanecarboxamide, N-[(2E,6Z)-2,6-dodecadienyl]-Cyclopropanecarboxamide, N-[(2E)-3,7-dimethyl-2,6-octadienyl]-Cyclopropanecarboxamide, N-[(2Z)-3,7-dimethyl-2,6-octadienyl]-Propanamide, N-[(2E)-3,7-dimethyl-2,6-octadienyl]- 2-methyl-Propanamide, N-[(2Z)-3,7-dimethyl-2,6-octadienyl]- 2-methyl-Acetamide, N-[(2Z,6Z)-2,6-nonadienyl]-Acetamide, N-[(2E,6Z)-2,6-nonadienyl]-Acetamide, N-[(2Z,6Z)-2-methyl-2,6-nonadienyl]-Acetamide, N-[(2Z,6Z)-2-methyl-2,6-nonadienyl]-Cyclopropanecarboxamide, N-[[2-methyl-2-(4-methyl-3-pentenyl)cyclopropyl)methyl]-Acetamide, N-[[2-methyl-2-(4-methyl-3-pentenyl)cyclopropyl]methyl]-Cyclopropanecarboxamide, N-methyl-N-[(2E,6Z)-2,6-nonadienyl]-Cyclopropanecarboxamide, N-[(2E)-3,7-dimethyl-2,6-octadienyl]-N-methyl-Cyclopropanecarboxamide, N-[(2E)-3,7-dimethyl-2,6-octadienyl]-N-ethyl-Propanamide, N-[(2E,6Z)-2,6-nonadienyl]-N-cyclopropylmethyl-.
The present invention also provides a method for enhancing or modifying the salt flavor of a food through the incorporation of an organoleptically acceptable level of the compounds described herein. The compounds can be used individually or in combination with other salt enhancing compounds of the present invention. In addition, the salt enhancing materials of the present invention can be used in combination with other salt enhancing compositions known in the art, including those materials listed in co-pending applications US Serial Number 10/919,631 filed on August 17, 2004; US Serial Number 10/861,751 filed on June 4, 2004; and US Serial Number 10/783,652 filed February 20, 2004; and also include cetylpyridium chloride, bretylium tosylate, various polypepti des, mixtures of calcium salts of ascorbic acid, sodium chloride and potassium chloride, as described in various U.S. Patents 4,997,672; 5,288,510; 6,541,050 and U.S.
Patent Application 2003/0091721.
The salt taste enhancing compounds of the present invention may be employed to enhance the perceived salt taste of any salts used in food or beverage products. The preferred salt taste to be enhanced by the compounds of the present invention is that of sodium chloride, primarily because of the discovery that ingestion of large amounts of sodium may have adverse effects on humans and the resultant desirability of reducing salt content while retaining salt taste.
In addition, the compounds of the present invention may also be employed to enhance the perceived salt taste of known salty tasting compounds which may be used as salt substitutes, including potassium chloride and ribonucleotides. Suitable compounds also include cationic amino acids and low molecular weight dipeptides. Specific examples of these compounds are arginine hydrochloride, arginine ammonium chloride, lysine hydrochloride and lysine-ornithine hydrochloride. These compounds exhibit a salty taste but are typically useful only at low concentrations since they exhibit a bitter flavor at higher concentrations. Thus, it is feasible to reduce the sodium chloride content of a food or beverage product by first formulating a food or beverage with less sodium chloride than is necessary to achieve a desired salt taste and then adding to said food or beverage the compounds of the present invention in an amount sufficient to potentiate the salt taste of said salted food or beverage to reach said desired taste.

In addition, the sodium chloride content may be further reduced by substituting a salty-tasting cationic amino acid, a low molecular weight dipeptide or mixtures thereof for at least a portion of the salt.
In a preferred embodiment of the present invention we have found the compound of the present invention are materials used in combination with each other or other salt enhancing materials in weight ratios of from about 1:10 to about 10:1, typically from about 1:3 to about 3:1; more preferably from about 1:l on a weight basis.
In a highly preferred embodiment we have discovered that the compounds of the present invention when used in combination with the compounds disclosed in co-pending application US Serial Number 10/783,652 filed February 20, 2004. The preferred compounds disclosed in this application include but are not limited to:
N,N,3,7-Tetramethylocta-2,6-dienamide,(2E)-2-propenamide, 3-(3-cyclohexen-1-yl)-N-ethyl-,(2E)-3,7-dimethyl-2,6-octadienamide, N-ethyl-,(2E)-2,6-nonadienamide, N,N-dimethyl-, (2E,6Z)-2,6-nonadienamide, N-cyclopropyl, 2-methyl-, (2E,62)-2,6-dodecadienamide, N-ethyl-, (2E,6Z)-2,6-nonadienamide, N-cyclopropyl-, (2E,6Z)-2,6-nonadienamide, N-ethyl-, (2E,6Z)-_ The mixtures of the compounds range from about 1:10 to 10:1 weight percent, preferably from about 1:5 to about 5:1 weight percent, most preferably in a 1:2 to a 2:1 weight ratio of the compounds.
Combinations that have been found to provide high levels of salt and umami enhancing effects to products are compounds of the present invention:

2-butenamide, N-[(2E)-3,7-dimethyl-2,6-octadienyl]-, (2E)-2-butenamide, N-[(2Z)-3,7-dimethyl-2,6-octadienyl]-, (2E)-2-butenamide, N-[(2E)-3,7-dimethyl-2,6-octadienyl]-3-methyl-2-butenamide, N-[(2Z)-3,7-dimethyl-2,6-octadienyl]-3-methyl-2-butenamide, N-[(2E)-3,7-dimethyl-2,6-octadienyl]-2-methyl-(2E)-2-butenamide, N-[(2Z)-3,7-dimethyl-2,6-octadienyl]-2-methyl-(2E)-Cyclopropanecarboxamide, N-[(2Z,6Z)-2,6-nonadienyl]-Cyclopropanecarboxamide, N-[(2E,6Z)-2,6-nonadienyl]-Cyclopropanecarboxamide, N-[(2E)-3-(3-cyclohexen-1-yl)-2-propenyl]-Cyclopropanecarboxamide, N-[(2E,6Z)-2,6-dodecadienyl]-Cyclopropanecarboxamide, N-[(2E)-3,7-dimethyl-2,6-octadienyl]-Cyclopropanecarboxamide, N-[(2Z)-3,7-dimethyl-2,6-octadienyl]-Propanamide, N-[(2E)-3,7-dimethyl-2,6-octadienyl]- 2-methyl-Propanamide, N-[(2Z)-3,7-dimethyl-2,6-octadienyl]- 2-methyl-Acetamide, N-[(2Z,6Z)-2,6-nonadienyl]-Acetamide, N-[(2E,6Z)-2,6-nonadienyl]-Acetamide, N-[(2Z,6Z)-2-methyl-2,6-nonadienyl]-Acetamide, N-[(2Z,6Z)-2-methyl-2,6-nonadienyl]-Cyclopropanecarboxamide, N-[[2-methyl-2-(4-methyl-3-pentenyl)cyclopropyl]methyl]-Acetamide, N-[[2-methyl-2-(4-methyl-~-pentenyl)cyclopropyl]methyl]-Cyclopropanecarboxamide, N-methyl-N-[(2E,6Z)-2,6-nonadienyl]-Cyclopropanecarboxamide, N-[(2E)-3,7-dimethyl-2,6-octadienyl]-N-methyl-Cyclopropanecarboxamide, N-[(2E)-3,7-dimethyl-2,6-octadienyl]-N-ethyl-Propanamide, N-[(2E,6Z)-2,6-nonadienyl]-N-cyclopropylmethyl-N,N,3,7-Tetramethylocta-2,6-dienamide,(2E)-2-propenamide, 3-(3-cyclohexen-1-yl)-N-ethyl-,(2E)-3,7-dimethyl-2,6-octadienamide, N-ethyl-,(2E)-2,6-nonadienamide, N,N-dimethyl-, (2E,6Z)-2,6-nonadienamide, N-cyclopropyl, 2-methyl-, (2E,6Z)-2,6-Bode cadienamide, N-ethyl-, (2E,6Z)-2,6-nonadienamide, N-cyclopropyl-, (2E,6Z)-2,6-nonadienamide, N-ethyl-, (2E,6Z)-.
The highly preferred weight ratios of these mixtures is from about 2:1 to about 1:2 on a weight basis. Most highly preferred combination is the mixture of Cyclopropanecarboxamide, N-[(2E)-3,7-dimethyl-2,6-octadienyl]- with 2,6-nonadienamide, N-cyclopropyl-, (2E,6Z)- and 2,6-nonadienamide, N-ethyl-, (2E,6Z)-in the ratio about 2:1:1 by weight, with a total use level of 8ppm. For purpose of illustration that would be a usage level of about 4, 2 and 2 parts per million respectively by weight in a product such as a foodstuff.
The term "foodstuff" as used herein includes both solid and liquid ingestible materials for man or animals, which materials usually do, but need not, have nutritional value. Thus, foodstuffs include food products, such as, meats, gravies, soups, convenience foods, malt, alcoholic and other beverages, milk and dairy products, seafood, including fish, crustaceans, mollusks and the like, candies, vegetables, cereals, soft drinks, snacks, dog and cat foods, other veterinary products and the like.
When the compounds of this invention are used in a flavoring composition, they can be combined with conventional flavoring materials or adjuvants. Such co-ingredients or flavor adjuvants are well known in the art for such use and have been extensively described in the literature. Requirements of such adjuvant materials are: (1) that they be non-reactive with the compounds of our invention; (2) that they be organoleptically compatible with the compounds of our invention whereby the flavor of the ultimate consumable material to which the compounds are added is not detrimentally affected by the use of the adjuvant;
and (3) that they be ingestible acceptable and thus nontoxic or otherwise non-deleterious. Apart from these requirements, conventional materials can be used and broadly include other flavor materials, vehicles, stabilizers, thickeners, surface active agents, conditioners and flavor intensifiers.
Such conventional flavoring materials include saturated fatty acids, unsaturated fatty acids and amino acids; alcohols including primary and secondary alcohols, esters, carbonyl compounds including ketones, other than the dienalkylamides of our invention and aldehydes; lactones; other cyclic organic materials including benzene derivatives, acyclic compounds, heterocyclics such as furans, pyridines, pyrazines and the like;
sulfur-containing compounds including thiols, sulfides, disulfides and the like; proteins; lipids, carbohydrates; so-called flavor potentiators such as monosodium glutamate;
magnesium glutamate, calcium glutamate, guanylates and inosinates; natural flavoring materials such as hydrolyzates, cocoa, vanilla and caramel; essential oils and extracts such as anise eil, clove oil and the like and artificial flavoring materials such as vanillin, ethyl vanillin and the like.
Specific preferred flavor adjuvants include but are not limited to the following: arise oil; ethyl-2-methyl butyrate;
vanillin; cis-3-heptenol; cis-3-hexenol; trans-2-heptenal; butyl valerate; 2,3-diethyl pyrazine; methyl cyclo-pentenolone;
benzaldehyde; valerian oil; 3,4-dimethoxy-phenol; amyl acetate;
amyl cinnamate; y-butyryl lactone; furfural; trimethyl pyrazine;
phenyl acetic acid; isovaleraldehyde; ethyl maltol; ethyl vanillin: ethyl valerate; ethyl butyrate; cocoa extract; coffee extract; peppermint oil; spearmint oil; clove oil; anethol;
cardamom oil; wintergreen oil; cinnamic aldehyde; ethyl-2-methyl valerate; y-hexenyl lactone; 2,4-decadienal; 2,4-heptadienal;
methyl thiazole alcohol (4-methyl-5-~-hydroxyethyl thiazole); 2-methyl butanethiol; 4-mercapto-2-butanone; 3-mercapto-2-pentanone; 1-mercapto-2-propane; benzaldehyde; furfural; furfuryl alcohol; 2-mercapto propionic acid; alkyl pyrazine; methyl pyrazine: 2-ethyl-3-methyl pyrazine; tetramethyl pyrazine:
polysulf ides; dipropyl disulfide; methyl benzyl disulfide; alkyl thiophene; 2,3-dimethyl thiophene; 5-methyl furfural; acetyl furan; 2,4-decadienal; guiacol; phenyl acetaldehyde; ~-decalactone; d-limonene; acetoin: amyl acetate; maltol; ethyl butyrate; levulinic acid; piperonal; ethyl acetate; n-octanal; n-pentanal; n-hexanal; diacetyl; monosodium glutamate; mono-potassium glutamate; sulfur-containing amino acids, e.g., cysteine; hydrolyzed vegetable protein; 2-methylfuran-3-thiol; 2-methyldihydrofuran-3-thiol; 2,5-dimethylfuran-3-thiol; hydrolyzed fish protein; tetramethyl pyrazine; propylpropenyl disulfide;
propylpropenyl trisulfide; diallyl disulfide; diallyl trisulfide;
dipropenyl disulfide; dipropenyl trisulfide; 4-methyl-2-[(methyl-thio)-ethyl]-1,3-dithiolane; 4,5-dimethyl-2-(methylthiomethyl)-1,3-dithiolne: and 4-methyl-2-(methylthiomethyl)-1,3-dithiolane.
These and other flavor ingredients are provided in U.S. Patent Nos. 6,110,520 and 6,333,180.
The cyclopropylic amides, alkenylamides, and dienalkylamides of our invention or compositions incorporating them, as mentioned above, can be combined with one or more vehicles or carriers for adding them to the particular product.
Vehicles can be edible or otherwise suitable materials such as ethyl alcohol, propylene glycol, water and the like, as described above. Carriers include materials such as gum arabic, carrageenan, xanthan gum, guar gum and the like.
Cyclopropylic amides, alkenylamides, and dienalkylamides prepared according to our invention can be incorporated with the carriers by conventional means such as spray-drying, extrusion, drum-drying and the like. Such carriers can also include materials for coacervating the dienalkylamides of our invention to provide encapsulated products, as set forth above. When the carrier is an emulsion, the flavoring composition can also contain emulsifiers such as mono- and diglycerides or fatty acids and the like. With these carriers or vehicles, the desired physical form of the compositions can be prepared.
The quantity of cyclopropylic amides, alkenylamides, and dienalkylamides utilized should be sufficient to impart the desired flavor characteristic to the product, but on the other hand, the use of an excessive amount of the compounds is not only wasteful and uneconomical, but in some instances, too large a quantity may unbalance the flavor or other organoleptic properties of the product consumed. The quantity used will vary depending upon the ultimate foodstuff; the amount and type of flavor initially present in the foodstuff; the further process or treatment steps to which the foodstuff will be subjected;
regional and other preference factors; the type of storage, if any, to which the product will be subjected; and the preconsumption treatment such as baking, frying and so on, given to the product by the ultimate consumer. Accordingly, the terminology "organoleptically effective amount" and "sufficient amount" is understood in the context of the present invention to be quantitatively adequate to alter the flavor of the foodstuff.
With reference to the novel compounds of our invention, the synthesis is effected by means of the reaction of acid anhydride with amine, added either directly or in solution, according to the general scheme:

R6~NH2 + R2 R' '' R ~ N.~Rz R I O s I
Rs 2 Ra H Rs where R1, R2, R3, R°, RS and R6 have the meaning set forth in formula I, and structures 1 and 2 set forth above.

The synthesis of amine follows a literature procedure [The Journal of Organic Chemistry 1989, 54, 3292-3303]. The acid anhydride is dissolved in hexanes to which amine is added in 0.9 to 1.0 a quivalent at temperatures ranging 0°C to room temperature, most preferably from 10°C to 20°C. The resulting solution is aged for about 1-3 hours at room temperature.
The reaction can be quenched with aqueous sodium chloride, hydrogen chloride or sodium hydroxide depending upon the need to remove residual acid or amine. The mixture is extracted into ethereal solvent, washed to neutrality and solvent removed.
The crude product is purified by distillation or recrystallization depending on the physical properties. The reaction occurs in 35-70o mole yield based on amine.
In the case when acid anhydride is not readily available, the synthesis is effected by means of the reaction of acid with ethyl chloroformate in the presence of triethylamine and further reaction of the intermediate with amine, added either directly or in solution, according to the general scheme:
O
R2 RIO ~~) CI~O'Et Et3N Rl~ ~R
~OH Rs~N 2 C
R3 R5 Ra H Rs iii) Rs~NH2 Ra where Rl, R', R3, Rq, RS and R6 have the meaning set forth in formula I, and structures I and 2 set forth above.
The acid is dissolved in dichloromethane to which ethyl chloroformate is added in 1.0 to 2.0 equivalents at temperatures ranging from 0°C to room temperature, most preferably from 10°C
to 20°C. The resulting solution is cooled to -10°C to -30°C, and I~~1~~=~lrl~~S ~~.~ P'~E~'S ~ ~~L!~LI~E~.~
LA PI2ESENTE P~RTIE DE CETTE DEYLANDE OU CE BREVETS
COyIPREND PLUS D'UN TOME.
CECI EST LE TOyIE ~ DE
NOTE: Pour les tomes additionels, veillez contacter 1e Bureau Canadien des Brevets.
.~UiYI~~ ~,PPL,I~ATI~N S I PATENTS
TI3IS SECTION OF THE APPLICATION I P:~TEI~t T COL~('I'W 1~S ~iOi~E
THAN ONE VOLUME.
THIS IS V O L U1~IE \~__ O F
NOTE: For additional volumes alease contact the Canadian Patent Of ice.

Claims (73)

1. A N-substituted unsaturated alkyl amide compound having the structure selected from the group consisting of structure 1 and structure 2:

where R1 = H or Me;

R2 is selected from the group consisting of H, C1-C4 alkyl, alkenyl and methylene;

R3 is selected from the group consisting of H, C1-C8 straight or branched chain alkyl, alkenyl, dienalkyl and phenyl;

or if R1 = H, R2 and R3 taken together can represent cyclopropyl, cyclobutyl, cyclopentyl, cyclopentenyl, cyclohexyl, or cyclohexenyl;

R4 is selected from the group consisting of H, methyl and ethyl;

R5 is selected from the group consisting of H, methyl and ethyl;
and R6 is selected from the group consisting of H, C1-C9 straight or branched chain alkyl, alkenyl, alkyldienyl, acyclic or cyclic containing no more than one ring;

with the proviso that in structure 1 when R4 is H or methyl; and R5 = H or methyl, R6 may be selected from the group described above or phenyl, with the proviso that in structure 1, if R1=H, and R4=H, then R4 will not be H or methyl.

2. The compound of claim 1 wherein:

R1 = H or methyl;

R2 is selected from the group consisting of H, methyl and ethyl;

R3 is selected from the group consisting of H, C1-C4 alkyl, and alkenyl; or if R1 - H, R2 and R3 taken together is selected from the group consisting of cyclopropyl, cyclopentyl, cyclopentenyl, cyclohexyl and cyclohexenyl;
R4 is selected from the group consisting of H and methyl;
R5 is selected from the group consisting of H and methyl; and R6 is selected from the group consisting of C3-C7 straight or branched chain alkyl, or alkenyl, acyclic or cyclic containing no more than one ring, and in the case of structure 1, phenyl, with the proviso that in structure 1, if R1 = H and R2 - H, then R3 will not be H or methyl.

3. The compound of the formula wherein:

R1 = H or methyl;
R2 is selected from the group consisting of H and methyl;
R3 is selected from the group consisting of H, methyl, ethyl, allyl isopropyl, and propyl;
or if R1 is H, R2 and R2 taken together is selected from the group consisting of cyclopropyl, cyclopentyl, cyclopentenyl, cyclohexyl or cyclohexenyl;

R4 is selected from the group consisting of H or methyl;

R5 is selected from the group consisting of H or methyl; and R6 is selected from the group consisting of C6 straight or branched chain alkyl, alkenyl, cyclohexenyl or phenyl, with the proviso that if R1 = H and R2 = H, then R3 will not be H
or methyl.

4. The compound of the formula:

wherein R7 is selected from the group consisting of H, and methyl R8 is selected from the group consisting of H, and methyl, or R7 and R8 taken together can represent cyclopropyl, R9 is selected from the group consisting of H or methyl; and R10 is selected from the group consisting of H or methyl, with the proviso that if R7 is H, then R8 will not be H or methyl.

5. A foodstuff comprising greater than about 50 parts per billion by weight of the compound of claim 1.

6. In combination, a consumable material selected from the group consisting of beverages, foodstuff, chewing gum, dental and oral hygiene products:

and an organoleptically acceptable level of the compound of claim 1.

7. The combination of claim 6 wherein the level of the organoleptically acceptable compound is greater than about 50 parts per billion.

8. The combination of claim 6 wherein the level of the organoleptically acceptable compound is provided at a level of from about 0.01 parts per million to about 50 parts per million by weight.

9. A method of enhancing the salty taste of salt-containing beverages, foodstuff, chewing gum, dental and oral hygiene products which comprises adding a salt enhancing level of the structure selected from the group consisting of structure 1 and structure 2:

where R1 = H or Me;

R2 is selected from the group consisting of H, C1-C4 alkyl, alkenyl and methylene;

R3 is selected from the group consisting of H, C1-C8 straight or branched chain alkyl, alkenyl, dienalkyl and phenyl;

or if R1 - H, R2 and R3 taken together can represent cyclopropyl, cyclobutyl, cyclopentyl, cyclopentenyl, cyclohexyl, or cyclohexenyl;

R4 is selected from the group consisting of H, methyl and ethyl;

R5 is selected from the group consisting of H, methyl and ethyl;\
and R6 is selected from the group consisting of H, C1-C9 straight or branched chain alkyl, alkenyl, alkyldienyl, acyclic or cyclic containing no more than one ring;

with the proviso that in structure 1 when R4 is H or methyl; and R5 = H or methyl, R6 may be selected from the group described above or phenyl.

10. The combination comprising:

(a) the compound used in the method of claim 9;

(b) and a foodstuff.

11. The combination of claim 10 wherein the compound of claim 9 is described by structure 1.

12. An organoleptically acceptable combination comprising (a) the compound used in the method of claim 9;

(b) a second salt taste enhancing material;

wherein the weight ratio of (a) to (b) is from about 1 to 10 from about 10 to 1.

13. The combination of claim 12 wherein the weight ratio of (a) to (b) ranges from about 1 to 5 from about 5 to 1.

14. The combination of claim 12 wherein the ratio of (a) to (b) ranges from about 1 to 3 to about 3 to 1.

15. The combination of claim 12 wherein the compound of claim 9 is selected from the group consisting of:

2-butenamide, N-[(2E)-3,7-dimethyl-2,6-octadienyl]-, (2E)-;
2-butenamide, N-[(2Z)-3,7-dimethyl-2,6-octadienyl]-, (2E)-;
2-butenamide, N-[(2E)-3,7-dimethyl-2,6-octadienyl]-3-methyl-;
2-butenamide, N-[(2Z)-3,7-dimethyl-2,6-octadienyl]-3-methyl-;
Cyclopropanecarboxamide, N-[(2Z,6Z)-2,6-nonadienyl]-;
Cyclopropanecarboxamide, N-[(2E,6Z)-2,6-nonadienyl]-;
Cyclopropanecarboxamide, N-[(2E)-3-(3-cyclohexen-1-yl)-2-propenyl]-;
Cyclopropanecarboxamide, N-[(2E,6Z)-2,6-dodecadienyl]-;
Cyclopropanecarboxamide, N-[(2E)-3,7-dimethyl-2,6-octadienyl]-;
and Cyclopropanecarboxamide, N-[(2Z)-3,7-dimethyl-2,6-octadienyl]-.

16. A foodstuff or beverage containing the combination of claim 12 wherein the salt taste enhancer (a) is selected from the group consisting of:
2-butenamide, N-[(2E)-3,7-dimethyl-2,6-octadienyl]-, (2E)-;
2-butenamide, N-[(2Z)-3,7-dimethyl-2,6-octadienyl]-, (2E)-;
2-butenamide, N-[(2E)-3,7-dimethyl-2,6-octadienyl]-3-methyl-;
2-butenamide, N-[(2Z)-3,7-dimethyl-2,6-octadienyl]-3-methyl-;
Cyclopropanecarboxamide, N-[(2Z,6Z)-2,6-nonadienyl]-;
Cyclopropanecarboxamide, N-[(2E,6Z)-2,6-nonadienyl]-;
Cyclopropanecarboxamide, N-[(2E)-3-(3-cyclohexen-1-yl)-2-propenyl]-:
Cyclopropanecarboxamide, N-[(2E,6Z)-2,6-dodecadienyl]-;
Cyclopropanecarboxamide, N-[(2E)-3,7-dimethyl-2,6-octadienyl]-;
and Cyclopropanecarboxamide, N-[(2Z)-3,7-dimethyl-2,6-octadienyl]-.

17. The foodstuff or beverage of claim 16 wherein the salt taste enhancer (b) is selected from the group consisting of N,N,3,7-Tetramethylocta-2,6-dienamide,(2E)-;
2-propenamide, 3-(3-cyclohexen-1-yl)-N-ethyl-,(2E)-;
3,7-dimethyl-2,6-octadienamide, N-ethyl-,(2E)-;
2,6-nonadienamide, N,N-dimethyl-, (2E,6Z)-;
2,6-nonadienamide, N-cyclopropyl, 2-methyl-, (2E,6Z)-;
2,6-dodecadienamide, N-ethyl-, (2E,6Z)-;
2,6-nonadienamide, N-cyclopropyl-, (2E,6Z)-; and 2,6-nonadienamide, N-ethyl-, (2E,6Z)-.

18. A process for augmenting, enhancing or imparting an umami taste to a foodstuff, chewing gum, medicinal product, toothpaste, alcoholic beverage, aqueous beverage or soup comprising the step of adding to a foodstuff, chewing gum, medicinal product, toothpaste, alcoholic beverage, aqueous beverage or soup an organoletically acceptable level of the compound used in the method of claim 9.

19. The process of claim 18 wherein the level of the organoleptically acceptable level is greater than about 50 parts per billion by weight.

20. In combination an organoleptically acceptable amount of the compound having the structure selected from the group consisting of structure 1 and structure 2:

where R1 = H or Me;
R2 is selected from the group consisting of H, C1-C4 alkyl, alkenyl and methylene;

R3 is selected from the group consisting of H, C1-C8 straight or branched chain alkyl, alkenyl, dienalkyl and phenyl;

or if R1 = H, R2 and R3 taken together can represent cyclopropyl, cyclobutyl, cyclopentyl, cyclopentenyl, cyclohexyl, or cyclohexenyl;
R4 is selected from the group consisting of H, methyl and ethyl;
R5 is selected from the group consisting of H, methyl and ethyl;
and R6 is selected from the group consisting of H, C1-C9 straight or branched chain alkyl, alkenyl, alkyldienyl, acyclic or cyclic containing no more than one ring;
with the proviso that in structure 1 when R4 is H or methyl; and R5 = H or methyl, R6 may be selected from the group described above or phenyl;
and sodium chloride.

21. The combination of claim 20 containing an additional salt substitute compounds.

22. The combination of claim 21 where the salt substitute compound is selected from the group consisting of potassium chloride, ribonucleotides, cationic amino acids, low molecular weight dipeptides, monosodium glutamates and yeasts.

23. The combination of claim 21 wherein the salt substitute compound is selected from the group consisting of arginine hydrochloride, arginine ammonium chloride, lysine hydrochloride and lysine-ornithine hydrochloride.

24. The combination of claim 20 provided to a foodstuff, beverage, chewing gum, medicinal product, or toothpaste at a level of greater than 50 parts per billion.

25. In combination Cyclopropanecarboxamide, N-[(2E)-3,7-dimethyl-2,6-octadienyl]- ; 2,6-nonadienamide, N-cyclopropyl-, (2E,6Z)-; and 2,6-nonadienamide, N-ethyl-, (2E,6Z)-.

26. The combination of claim 25 wherein the materials are provided in a weight ratio of about 2:1:1.

27. The combination of claim 26 provided to a foodstuff, beverage, chewing gum, medicinal product, or toothpaste.

28. The combination of claim 25 provided foodstuff, beverage, chewing gum, medicinal product, or toothpaste at a level greater than about 50 parts per billion.

29. A N-substituted unsaturated alkyl amide compound having the structure selected from the group consisting of structure 3 and structure 4:

where R1 = H or methyl;
R2 is selected from the group consisting of H, C1-C4 alkyl, alkenyl and methylene;
R3 is selected from the group consisting of H, C1-C8 straight or branched chain alkyl, alkenyl, dienalkyl and phenyl;

or if R1 - H, R2 and R3 taken together can represent cyclopropyl, cyclobutyl, cyclopentyl, cyclopentenyl, cyclohexyl, or cyclohexenyl;
or if R1 = Me, R2 and R3 taken together can represent or cyclopropyl, R4 is selected from the group consisting of C1-C4 alkyl, alkenyl; removed methylene R5 is selected from the group consisting of H, methyl or ethyl;
R5 is selected from the group consisting of H, methyl and ethyl;
R6 is selected from the group consisting of H, C1-C9 straight or branched chain alkyl, alkenyl, alkyldienyl, acyclic or containing no more than one ring:
except for in the case of structure 3 when if R5 - H or methyl and R6 = H or methyl, R7 as described above and phenyl.

30. A foodstuff comprising greater than about 50 parts per billion by weight of the compound of claim 29.

31. In combination, a consumable material selected from the group consisting of beverages, foodstuff, chewing gum, dental and oral hygiene products:
and an organoleptically acceptable level of the compound of claim 29.

32. The combination of claim 31 wherein the level of the organoleptically acceptable compound is greater than about 50 parts per billion.

33. The combination of claim 31 wherein the level of the organoleptically acceptable compound is provided at a level of from about 0.01 parts per million to about 50 parts per million by weight.

34. A method of enhancing the salty taste of salt-containing beverages, foodstuff, chewing gum, dental and oral hygiene products which comprises adding a salt enhancing level of the structure selected from the group consisting of structure 3 and structure 4:

where R1 - H or methyl;
R2 is selected from the group consisting of H, C1-C4 alkyl, alkenyl and methylene;
R3 is selected from the group consisting of H, C1-C8 straight or branched chain alkyl, alkenyl, dienalkyl and phenyl;
or if R1 - H, R2 and R3 taken together can represent cyclopropyl, cyclobutyl, cyclopentyl, cyclopentenyl, cyclohexyl, or cyclohexenyl;

or if R1 - Me, R2 and R3 taken together can represent or cyclopropyl, R4 is selected from the group consisting of C1-C4 alkyl, alkenyl; removed methylene R5 is selected from the group consisting of H, methyl or ethyl;
R6 is selected from the group consisting of H, methyl and ethyl;
R7 is selected from the group consisting of H, C1-C9 straight or branched chain alkyl, alkenyl, alkyldienyl, acyclic or containing no more than one ring;
except for in the case of structure 3 when if R5 - H or methyl and R6 = H or methyl, R7 as described above and phenyl.

35. The combination comprising:
(a) the compound used in the method of claim 34;
(b) and a foodstuff.

36. The combination of claim 35 wherein the compound of claim 34 is described by structure 3.

37. An organoleptically acceptable combination comprising (a) the compound used in the method of claim 34;
(b) a second salt taste enhancing material;
wherein the weight ratio of (a) to (b) is from about 1 to from about 10 to 1.

38. The combination of claim 37 wherein the weight ratio of (a) to (b) ranges from about 1 to 5 from about 5 to 1.

39. The combination of claim 37 wherein the ratio of (a) to (b) ranges from about 1 to 3 to about 3 to 1.

40. A process for augmenting, enhancing or imparting an umami taste to a foodstuff, chewing gum, medicinal product, toothpaste, alcoholic beverage, aqueous beverage or soup comprising the step of adding to a foodstuff, chewing gum, medicinal product, toothpaste, alcoholic beverage, aqueous beverage or soup an organoletically acceptable level of the compound used in the method of claim 34.

41. The process of claim 40 wherein the level of the organoleptically acceptable level is greater than about 50 parts per billion by weight.

42. A N-substituted unsaturated alkyl amide compound having the structure:

where R1 - H or methyl;
R2 is selected from the group consisting of H, C1-C9 alkyl, alkenyl and methylene;
R3 is selected from the group consisting of H, C1-C8 straight or branched chain alkyl, alkenyl, dienalkyl and phenyl;
or if R1 = H, R2 and R3 taken together can represent cyclopropyl, cyclobutyl, cyclopentyl, cyclopentenyl, cyclohexyl, or cyclohexenyl;

or if R1 = Me, R2 and R3 taken together can represent or cyclopropyl, R4 is selected from the group consisting of C1-C4 alkyl;
R5 is selected from the group consisting of H, methyl or ethyl;
R6 is selected from the group consisting of H, methyl and ethyl;
R7 is selected from the group consisting of H, C1-C9 straight or branched chain alkyl, alkenyl, alkyldienyl, acyclic or containing no more than one ring;
except for in the case of structure 4 when if R5 - H or methyl and R6 = H or methyl, R7 as described above and phenyl.

43. A foodstuff comprising greater than about 50 parts per billion by weight of the compound of claim 42.

44. In combination, a consumable material selected from the group consisting of beverages, foodstuff, chewing gum, dental and oral hygiene products;
and an organoleptically acceptable level of the compound of claim 42.

45. The combination of claim 44 wherein the level of the organoleptically acceptable compound is greater than about 50 parts per billion.

46. The combination of claim 44 wherein the level of the organoleptically acceptable compound is provided at a level of from about 0.01 parts per million to about 50 parts per million by weight.

47. A method of enhancing the salty taste of salt-containing beverages, foodstuff, chewing gum, dental and oral hygiene products which comprises adding a salt enhancing level of the structure:

where R1 - H or methyl;
R2 is selected from the group consisting of H, C1-C4 alkyl, alkenyl and methylene;
R3 is selected from the group consisting of H, C1-C8 straight or branched chain alkyl, alkenyl, dienalkyl and phenyl;
or if R1 - H, R2 and R3 taken together can represent cyclopropyl, cyclobutyl, cyclopentyl, cyclopentenyl, cyclohexyl, or cyclohexenyl;
or if R1 - Me, R2 and R3 taken together can represent or cyclopropyl, R4 is selected from the group consisting of C1-C4 alkyl;
R5 is selected from the group consisting of H, methyl or ethyl;
R6 is selected from the group consisting of H, methyl and ethyl;
R7 is selected from the group consisting of H, C1-C9 straight or branched chain alkyl, alkenyl, alkyldienyl, acyclic or containing no more than one ring;

except for in the case of structure 4 when if R5 = H or methyl and R6 = H or methyl, R7 as described above and phenyl.

48. The combination comprising:
(a) the compound used in the method of claim 47;
(b) and a foodstuff.

49. An organoleptically acceptable combination comprising (a) the compound used in the method of claim 47;
(b) a second salt taste enhancing material;
wherein the weight ratio of (a) to (b) is from about 1 to from about 10 to 1.

50. The combination of claim 47 wherein the weight ratio of (a) to (b) ranges from about 1 to 5 from about 5 to 1.

51. The combination of claim 47 wherein the ratio of (a) to (b) ranges from about 1 to 3 to about 3 to 1.

52. A process for augmenting, enhancing or imparting an umami taste to a foodstuff, chewing gum, medicinal product, toothpaste, alcoholic beverage, aqueous beverage or soup comprising the step of adding to a foodstuff, chewing gum, medicinal product, toothpaste, alcoholic beverage, aqueous beverage or soup an organoletically acceptable level of the compound used in the method of claim 47.

53. The process of claim 52 wherein the level of the organoleptically acceptable level is greater than about 50 parts per billion by weight.

54. A foodstuff or beverage containing wherein the salt or umami taste enhancer (a) is selected from the group consisting of:
2-butenamide, N-[(2E)-3,7-dimethyl-2,6-octadienyl]-, (2E)-2-butenamide, N-[(2Z)-3,7-dimethyl-2,6-octadienyl]-, (2E)-2-butenamide, N-[(2E)-3,7-dimethyl-2,6-octadienyl]-3-methyl-2-butenamide, N-[(2Z)-3,7-dimethyl-2,6-octadienyl]-3-methyl-2-butenamide, N-[(2E)-3,7-dimethyl-2,6-octadienyl]-2-methyl-(2E)-2-butenamide, N-[(2Z)-3,7-dimethyl-2,6-octadienyl]-2-methyl-(2E)-Cyclopropanecarboxamide, N-[(2Z,6Z)-2,6-nonadienyl]-Cyclopropanecarboxamide, N-[(2E,6Z)-2,6-nonadienyl]-Cyclopropanecarboxamide, N-[(2E)-3-(3-cyclohexen-1-yl)-2-propenyl]-Cyclopropanecarboxamide, N-[(2E,6Z)-2,6-dodecadienyl]-Cyclopropanecarboxamide, N-[(2E)-3,7-dimethyl-2,6-octadienyl]-Cyclopropanecarboxamide, N-[(2Z)-3,7-dimethyl-2,6-octadienyl]-Propanamide, N-[(2E)-3,7-dimethyl-2,6-octadienyl]- 2-methyl-Propanamide, N-[(2Z)-3,7-dimethyl-2,6-octadienyl]- 2-methyl-Acetamide, N-[(2Z,6Z)-2,6-nonadienyl]-Acetamide, N-[(2E,6Z)-2,6-nonadienyl]-Acetamide, N-[(2Z,6Z)-2-methyl-2,6-nonadienyl]-Acetamide, N-[(2Z,6Z)-2-methyl-2,6-nonadienyl]-Cyclopropanecarboxamide, N-[[2-methyl-2-(4-methyl-3-pentenyl)cyclopropyl]methyl]-Acetamide, N-[[2-methyl-2-(4-methyl-3-pentenyl)cyclopropyl]methyl]-Cyclopropanecarboxamide, N-methyl-N-[(2E,6Z)-2,6-nonadienyl)-Cyclopropanecarboxamide, N-[(2E)-3,7-dimethyl-2,6-octadienyl]-N-methyl-Cyclopropanecarboxamide, N-[(2E)-3,7-dimethyl-2,6-octadienyl]-N-ethyl-Propanamide, N-[(2E,6Z)-2,6-nonadienyl]-N-cyclopropylmethyl-N,N,3,7-Tetramethylocta-2,6-dienamide,(2E)-2-propenamide, 3-(3-cyclohexen-1-yl)-N-ethyl-,(2E)-3,7-dimethyl-2,6-octadienamide, N-ethyl-,(2E)-2,6-nonadienamide, N,N-dimethyl-, (2E,6Z)-2,6-nonadienamide, N-cyclopropyl, 2-methyl-, (2E,6Z)-2,6-dodecadienamide, N-ethyl-, (2E,6Z)-2,6-nonadienamide, N-cyclopropyl-, (2E,6Z)-2,6-nonadienamide, N-ethyl-, (2E,6Z)-.

55. A N-substituted unsaturated alkyl amide compound having the structure selected from the group consisting of structure 1 and structure 2:

where R1 = H or methyl;

R2 is selected from the group consisting of H, C1-C9 alkyl, alkenyl and methylene;

R3 is selected from the group consisting of H, C1-C8 straight or branched chain alkyl, alkenyl, dienalkyl and phenyl;

or if R1 = H, R2 and R3 taken together can represent cyclopropyl, cyclobutyl, cyclopentyl, cyclopentenyl, cyclohexyl, or cyclohexenyl;

or if R1 = Me, R2 and R3 taken together can represent or cyclopropyl, R4 is selected from the group consisting of H, methyl or ethyl;

R5 is selected from the group consisting of H, methyl and ethyl;

R6 is selected from the group consisting of H, C1-C9 straight or branched chain alkyl, alkenyl, alkyldienyl, acyclic or containing no more than one ring;

with the proviso that in structure 1 when R4 is H or methyl; and R5 is H or methyl, R6 may be selected from the group described above or phenyl, and if R1=H and R2=H, then R3 can not be H or methyl unless R4=R5=H.

56. The compound of the formula where R1 = H or methyl;

R2 is selected from the group consisting of H, C1-C9 alkyl, alkenyl and methylene;

R3 is selected from the group consisting of H, C1-C8 straight or branched chain alkyl, alkenyl, dienalkyl and phenyl;

or if R1 - H, R2 and R3 taken together can represent cyclopropyl, cyclobutyl, cyclopentyl, cyclopentenyl, cyclohexyl, or cyclohexenyl;

or if R1 = Me, R2 and R3 taken together can represent or cyclopropyl, R4 is selected from the group consisting of H, methyl or ethyl;

R5 is selected from the group consisting of H, methyl and ethyl;

R6 is selected from the group consisting of H, C1-C9 straight or branched chain alkyl, alkenyl, alkyldienyl, acyclic or containing no more than one ring;

with the proviso that in structure 1 when R9 is H or methyl; and R5 is H or methyl, R6 may be selected from the group described above or phenyl, and if R1=H and R2=H, then R3 can not be H or methyl unless R4=R5=H.

57. A foodstuff comprising greater than about 50 parts per billion by weight of the compound of claim 55.

58. In combination, a consumable material selected from the group consisting of beverages, foodstuff, chewing gum, dental and oral hygiene products;

and an organoleptically acceptable level of the compound of claim 55.

59. The combination of claim 58 wherein the level of the organoleptically acceptable compound is greater than about 50 parts per billion.

60. The combination of claim 58 wherein the level of the organoleptically acceptable compound is provided at a level of from about 0.01 parts per million to about 50 parts per million by weight.

61. A method of enhancing the salty taste of salt-containing beverages, foodstuff, chewing gum, dental and oral hygiene products which comprises adding a salt enhancing level of the structure selected from the group consisting of structure 1 and structure 2:

where R1 = H or methyl;

R2 is selected from the group consisting of H, C1-C4 alkyl, alkenyl and methylene;

R3 is selected from the group consisting of H, C1-C8 straight or branched chain alkyl, alkenyl, dienalkyl and phenyl;

or if R1 = H, R2 and R3 taken together can represent cyclopropyl, cyclobutyl, cyclopentyl, cyclopentenyl, cyclohexyl, or cyclohexenyl;

or if R1 = Me, R2 and R3 taken together can represent or cyclopropyl, R4 is selected from the group consisting of H, methyl or ethyl;

R5 is selected from the group consisting of H, methyl and ethyl;

R6 is selected from the group consisting of H, C1-C9 straight or branched chain alkyl, alkenyl, alkyldienyl, acyclic or containing no more than one ring;

with the proviso that in structure 1 when R4 is H or methyl; and R5 is H or methyl, R6 may be selected from the group described above or phenyl, and if R1=H and R2=H, then R3 can not be H or methyl unless R4=R5=H.

62. The combination comprising:

(a) the compound used in the method of claim 61;

(b) and a foodstuff.

63. The combination of claim 62 wherein the compound of claim 61 is described by structure 1.

64. An organoleptically acceptable combination comprising (a) the compound used in the method of claim 61;

(b) a second salt taste enhancing material;

wherein the weight ratio of (a) to (b) is from about 1 to 10 from about 10 to 1.

65. The combination of claim 64 wherein the weight ratio of (a) to (b) ranges from about 1 to 5 from about 5 to 1.

66. The combination of claim 64 wherein the ratio of (a) to (b) ranges from about 1 to 3 to about 3 to 1.

67. A process for augmenting, enhancing or imparting an umami taste to a foodstuff, chewing gum, medicinal product, toothpaste, alcoholic beverage, aqueous beverage or soup comprising the step of adding to a foodstuff, chewing gum, medicinal product, toothpaste, alcoholic beverage, aqueous beverage or soup an organoletically acceptable level of the compound used in the method of claim 61.

68. The process of claim 67 wherein the level of the organoleptically acceptable level is greater than about 50 parts per billion by weight.

69. In combination an organoleptically acceptable amount of the compound having the structure selected from the group consisting of structure 1 and structure 2:

where R1 = H or methyl;

R2 is selected from the group consisting of H, C1-C4 alkyl, alkenyl and methylene;

R3 is selected from the group consisting of H, C1-C8 straight or branched chain alkyl, alkenyl, dienalkyl and phenyl;

or if R1 = H, R2 and R3 taken together can represent cyclopropyl, cyclobutyl, cyclopentyl, cyclopentenyl, cyclohexyl, or cyclohexenyl;

or if R1 = Me, R2 and R3 taken together can represent or cyclopropyl, R4 is selected from the group consisting of H, methyl or ethyl;

R5 is selected from the group consisting of H, methyl and ethyl;

R6 is selected from the group consisting of H, C1-C4 straight or branched chain alkyl, alkenyl, alkyldienyl, acyclic or containing no more than one ring;

with the proviso that in structure 1 when R4 is H or methyl; and R5 is H or methyl, R6 may be selected from the group described and if R1=H and R2=H, then R3 can not be H or methyl unless R4=R5=H.

70. The combination of claim 69 containing an additional salt substitute compounds.

71. The combination of claim 70 where the salt substitute compound is selected from the group consisting of potassium chloride, ribonucleotides, cationic amino acids, low molecular weight dipeptides, monosodium glutamates and yeasts.

72. The combination of claim 70 wherein the salt substitute compound is selected from the group consisting of arginine hydrochloride, arginine ammonium chloride, lysine hydrochloride and lysine-ornithine hydrochloride.

73. The combination of claim 70 provided to a foodstuff, beverage, chewing gum, medicinal product, or toothpaste at a level of greater than 50 parts per billion.