CA2518664C - Saturated and unsaturated n-alkamides exhibiting taste and flavor enhancement effect in flavor compositions - Google Patents

Abstract

The present invention is directed to novel compounds and a process for augmenting or imparting a flavor enhancement effect or modifying the perception of one or more of the five basic taste qualities sweet, sour, salt , bitter and umami, to a foodstuff, chewing gum, medicinal product, toothpaste, alcoholic beverage, aqueous beverage, snack, sauce or soup comprising the step of adding to a foodstuff, chewing gum, medicinal product, toothpaste, alcoholic beverage, aqueous beverage, snack, sauce or soup a flavor enhancement or modification of basic taste quality augmenting, enhancing or imparting quantity and concentration of at least one N-substituted unsaturated alkyl amide defined according to the structures:
(see above formula)

Description

=
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SATURATED AND UNSATURATED N-ALKAMIDES EXHIBITING TASTE AND
FLAVOR ENHANCEMENT EFFECT IN FLAVOR COMPOSITIONS
FIELD OF THE INVENTION
Saturated and unsaturated N-alkamide compounds having sweet, salt or umami taste and flavor enhancement quality.
BACKGROUND OF THE INVENTION
The term Umami, from the Japanese word to describe savory or meaty, is the term used to describe the unique overall fullness, savory or salivatory taste of food. Materials that exhibit this taste quality generally potentate the intensity of glutamate solutions and this is one important characteristic of umami taste. It is increasingly becoming recognized as the fifth sense of taste, the others being sour, sweet, salt and bitter.
Compounds traditionally described as possessing this character are monosodium glutamate (MSG), protein hydrolysates, some amino acids and certain nucleotides and phosphates.
MSG is the most widely used material as a 'taste enhancer' where it synergizes the perception of 'savory' ingredients, but has also been alleged to cause allergic reaction to a proportion of the population.
Among other chemical compounds, several nucleotides have also been described to exhibit the umami effect including Adenosine 5'-(trihydrogen diphosphate), 5'-Cytidylic acid (5'-CMP), 5'-Uridylic acid (5'-UMP), 5'-Adenylic acid (5'-AMP), 5'-Guanylic acid (5'-GMP), 5'-Inosinic acid (5'-IMP) and the di-sodium salts of 5'-Guanylic acid and 5'-Inosinic acid.

Recent literature cites an extensive range of other organic compounds as taste active components of mixtures shown to give the umami taste effect. These include but are not necessarily limited to: organic acids such as succinic acid, lactic acid, saturated straight chain aliphatic acids of six, eight, fourteen, fifteen, sixteen, and seventeen carbon chain lengths, Z4,Z7, Z10,Z13,Z16,Z19-docosahexaenoic acid, Z5,Z8,Z11,Z14,Z17-eicosapentaenoic acid, Z9,Z12, Z16, Z19-octadecadienoic acid, Z9-octadecenoic acid, glutaric acid, adipic acid, suberic acid, and malonic acid. Amino acids having umami effects reported in the literature include glutamic acid, aspartic acid, threonine, alanine, valine, histidine, praline, tyrosine, cystine, methionine, pyroglutamic acid, leucine, lycine, and glycine.
Dipeptides possessing umami properties include Val-Glu and Glu-Asp.
Other miscellaneous compounds having umami properties include alpha-amino adipic acid, malic acid, alpha -aminobutyric acid, alpha -aminoisobutyric acid, E2,E4-hexadienal, E2,E4-heptadienal, E2,E4-octadienal, E2,E4-decadienal, Z4-heptenal, E2,Z6-nonadienal, methional, E3,E5-octadien-2-one, 1,6-hexanediamine, tetramethylpyrazine, trimethylpyrazine, cis-6-dodecen-4-olide, glutamate glycoconjugates, fish sauce blended with anchovy paste (U.S.
Patent Application 2003/0142090) and a number of naturally occurring amino-acids.
Additionally, a variety of molecules are known by those skilled in the art to provide salt enhancement, these include but are not limited to Adenosine 5'-(trihydrogen diphosphate), 5'-Cytidylic acid (5'-CMP), 5'-Uridylic acid (5'-UMP), 5'-Adenylic acid (5'-AMP), 5'-Guanylic acid (5'-GNP), 5'-Inosinic acid (5'-IMP) and the di-sodium salts of 5'-Guanylic acid and 5'-Inosinic acid, (+)-(S)-Alapyridaine (chemical name N-(1-Carboxyethyl)-6-hydroxymethyl pyridinium-3-ol), succinic acid, cetylpyridium chloride, bretylium tosylate, various polypeptides, mixtures of calcium salts of ascorbic acid, potassium chloride, calcium chloride, magnesium chloride, arginine ammonium chloride, alpha-amino acids and their corresponding hydrogen chloride, ammonium and sodium salts and a number of natural plant extracts. Uses of these materials are described in various U.S. Patents 4,997,672;
5,288,510; 6,541,050, U.S. Patent Application 2003/0091721 and Eur. Pat. Appl. 2003/1291342.
Additionally, choline chloride has been shown to enhance salt and increase palatability of sodium chloride reduced systems, Physiol Behav. 1994,55(6), 1039-46.
In addition to this work, our work has included the identification of new flavor materials described in US Serial Number 10/919,631 filed on August 17, 2004; US Serial Number 10/861,751 filed on June 4, 2004; and US Serial Number 10/783,652 filed February 20, 2004.
Despite these disclosures there is an ongoing need for new flavor ingredients particularly those that exhibit advantageous properties for flavor enhancement or modulation, or more preferably the lowering of MSG and /or salt levels in foodstuffs.

SUMMARY OF THE INVENTION
The present invention relates to novel compounds and a process for augmenting or imparting a flavor enhancement effect or modifying the perception of one or more of the five basic taste qualities sweet, sour, salt , bitter and umami, to a foodstuff, chewing gum, medicinal product, toothpaste, alcoholic beverage, aqueous beverage, snack, sauce or soup comprising the step of adding to a foodstuff, chewing gum, medicinal product, toothpaste, alcoholic beverage, aqueous beverage, snack, sauce or soup a flavor enhancement or modification of basic taste quality augmenting, enhancing or imparting quantity and concentration of at least one N-substituted unsaturated alkyl amide defined according to the structures:

E/Z
R6 vN R2 R2 where Ri = H or methyl;
R2 is selected from the group consisting of H, C1-C4 alkyl, alkenyl and methylene;
R3 is selected from the group consisting of H, C1-C8 straight or branched chain alkyl, alkenyl, dienalkyl and phenyl;
or if R' = H, R2 and R3 taken together can represent L/
Li cyclopropyl, cyclobutyl, cyclopentyl, cyclopentenyl, cyclohexyl, or cyclohexenyl;

or if R1 = Me, R2 and R3 taken together can represent Li or cyclopropyl, R4 is selected from the group consisting of H, methyl or ethyl;
R5 is selected from the group consisting of H, methyl and ethyl;
R6 is selected from the group consisting of H, C1-C9 straight or branched chain alkyl, alkenyl, alkyldienyl, acyclic or containing no more than one ring;
except for in the case of structure 1 when if R4 = H or methyl and R5 = H or methyl, R6 as described above and phenyl.
The above formulae define novel compounds with the proviso that in structure 1, if R1-H and R2-H, then R3 can not be H or methyl unless R4--R5--H.
As used herein compounds described in structure 2 will be referred to as "cyclopropylic amides".
A second embodiment relates to novel compounds and a process for augmenting or imparting a flavor enhancement effect or modifying the perception of one or more of the five basic taste qualities sweet, sour, salt , bitter and umami, to a foodstuff, chewing gum, medicinal product, toothpaste, alcoholic beverage, aqueous beverage, snack, sauce or soup comprising the step of adding to a foodstuff, chewing gum, medicinal product, toothpaste, alcoholic beverage, aqueous beverage, snack, sauce or soup a flavor enhancement or modification of basic taste quality augmenting, enhancing or imparting quantity and concentration of at least one N-substituted unsaturated alkyl amide defined according to the structure:

E/Z
R6 NI R2 R6><r R2 where RI = H or methyl;
R2 is selected from the group consisting of H, C1-C4 alkyl, alkenyl and methylene;
R3 is selected from the group consisting of H, C1-C8 straight or branched chain alkyl, alkenyl, dienalkyl and phenyl;
or if Ri = H, R2 and R5 taken together can represent L' cyclopropyl, cyclobutyl, cyclopentyl, cyclopentenyl, cyclohexyl, or cyclohexenyl;
or if R2 = Me, R2 and R5 taken together can represent , L-1 or cyclopropyl, R4 is selected from the group consisting of 01-C4 alkyl, alkenyl; removed methylene R5 is selected from the group consisting of H, methyl or ethyl;
R6 is selected from the group consisting of H, methyl and ethyl;
127 is selected from the group consisting of H, C1-C9 straight or branched chain alkyl, alkenyl, alkyldienyl, acyclic or containing no more than one ring;
except for in the case of structure 3 when if R5 = H or methyl and R6 = H or methyl, R7 as described above and phenyl.

A third embodiment relates to novel compounds and a process for augmenting or imparting a flavor enhancement effect or modifying the perception of one or more of the five basic taste qualities sweet, sour, salt , bitter and umami, to a foodstuff, chewing gum, medicinal product, toothpaste, alcoholic beverage, aqueous beverage, snack, sauce or soup comprising the step of adding to a foodstuff, chewing gum, medicinal product, toothpaste, alcoholic beverage, aqueous beverage, snack, sauce or soup a flavor enhancement or modification of basic taste quality augmenting, enhancing or imparting quantity and concentration of at least one N-substituted unsaturated alkyl amide defined according to the structure:

where RI = H or methyl;
R2 is selected from the group consisting of H, C1-C4 alkyl, alkenyl and methylene;
R3 is selected from the group consisting of H, Cl-C straight or branched chain alkyl, alkenyl, dienalkyl and phenyl;
or if R' = H, R2 and R3 taken together can represent L' </
cyclopropyl, cyclobutyl, cyclopentyl, cyclopentenyl, cyclohexyl, or cyclohexenyl;
or if Rl = Me, R2 and R3 taken together can represent or cyclopropyl, R4 is selected from the group consisting of C1-C4 alkyl;

R5 is selected from the group consisting of H, methyl or ethyl;
R6 is selected from the group consisting of H, methyl and ethyl;
R/ is selected from the group consisting of H, C1-C9 straight or branched chain alkyl, alkenyl, alkyldienyl, acyclic or containing no more than one ring;
except for in the case of structure 4 when if R5 = H or methyl and R6 = H or methyl, R7 as described above and phenyl.
In addition to the novel compounds and the use of the compounds to enhance the taste of foodstuffs by the incorporation of the above ingredients and others set forth in this specification in foodstuff and other materials.
DETAILED DESCRIPTION OF THE INVENTION
The formula set forth above describes a general class of novel materials that we have found to enhance the flavor characteristics of food.
In a more preferred embodiment of the invention the amides have the structure set forth in 1 and 2 with wherein where R' = H or methyl;
R2 is selected from the group consisting of H, C1-C4 alkyl, alkenyl and methylene;
R3 is selected from the group consisting of H, Ci-C8 straight or branched chain alkyl, alkenyl, dienalkyl and phenyl;
or if R1 = H, R2 and R3 taken together can represent L' -, cyclopropyl, cyclobutyl, cyclopentyl, cyclopentenyl, cyclohexyl, or cyclohexenyl;

or if Rl = Me, R2 and R3 taken together can represent L' or cyclopropyl, R4 is selected from the group consisting of H, methyl or ethyl;
R5 is selected from the group consisting of H, methyl and ethyl;
R6 is selected from the group consisting of H, C1-C9 straight or branched chain alkyl, alkenyl, alkyldienyl, acyclic or containing no more than one ring;
except for in the case of structure I when if R4 = H or methyl and R5 = H or methyl, R6 as described above and phenyl.
The above compounds of the present invention can be used in accordance with the present method in enhancing the salt and umami effects in foods. The above formulae define novel compounds with the proviso that in structure 1, if R1=H and R2=H, then R3 can not be H or methyl unless R4=R5=H.
In a highly preferred embodiment of the invention the amides have the structure set forth below:

E/Z

Formula I

where Rl = H or methyl;
R2 is selected from the group consisting of H, 01-04 alkyl, alkenyl and methylene;
R3 is selected from the group consisting of H, 01-C8 straight or branched chain alkyl, alkenyl, dienalkyl and phenyl;
or if R1 = H, R2 and R3 taken together can represent L/
, cyclopropyl, cyclobutyl, cyclopentyl, cyclopentenyl, cyclohexyl, or cyclohexenyl;
or if R1 - Me, R2 and R3 taken together can represent L' or cyclopropyl, R4 is selected from the group consisting of H, methyl or ethyl;
R5 is selected from the group consisting of H, methyl and ethyl;
R5 is selected from the group consisting of H, 01-08 straight or branched chain alkyl, alkenyl, alkyldienyl, acyclic or containing no more than one ring;
except for in the case of structure 1 when if R4 = H or methyl and RE H or methyl, R5 as described above and phenyl.
The above compounds of the present invention can be used in accordance with the present method in enhancing the salt and umami effects in foods. The above formulae define novel compounds with the proviso that in structure 1, if R1=H and R2=H, then R3 can not be H or methyl unless R4=-R5=H.
As used herein the compounds under structure 1 and formula 1 will be referred to as "alkenylamides".
In the most preferred embodiment of the invention the amides have the structure set forth below:

E/Z

Formula II
wherein: R7 is selected from the group consisting of H, methyl;
R8 is selected from the group consisting of H or methyl, or R' and R8 taken together can represent cyclopropyl, R9 is selected from the group consisting of H or methyl; and Ri is selected from the group consisting of H or methyl.
The above compounds of the present invention can be used in accordance with the present method in enhancing the salt and umami effects in foods. The above compounds are also novel with the proviso that in Formula II, if R7 = H, then Re can not be H or methyl.
In another preferred embodiment of the invention the amides have the structure set forth below:

E/Z

where R1 = H or methyl;
R2 is selected from the group consisting of H, Cl-C4 alkyl, alkenyl and methylene;
R3 is selected from the group consisting of H, Ci-C8 straight or branched chain alkyl, alkenyl, dienalkyl and phenyl;

or if R' = H, R2 and R3 taken together can represent , cyclopropyl, cyclobutyl, cyclopentyl, cyclopentenyl, cyclohexyl, or cyclohexenyl;
or if Ri = Me, R2 and R2 taken together can represent L' or cyclopropyl, R4 is selected from the group consisting of C1-C4 alkyl, alkenyl and methylene;
R5 is selected from the group consisting of H, methyl or ethyl;
R6 is selected from the group consisting of H, methyl and ethyl;
R7 is selected from the group consisting of H, C1-C9 straight or branched chain alkyl, alkenyl, alkyldienyl, acyclic or containing no more than one ring;
except for in the case of structure 1 when if R5 = H or methyl and R6 = H or methyl, R7 as described above and phenyl.
In an additional embodiment of the invention a novel compounds and a process for augmenting or imparting a flavor enhancement effect or modifying the perception of one or more of the five basic taste qualities sweet, sour, salt , bitter and umami, to a foodstuff, chewing gum, medicinal product, toothpaste, alcoholic beverage, aqueous beverage, snack, sauce or soup comprising the step of adding to a foodstuff, chewing gum, medicinal product, toothpaste, alcoholic beverage, aqueous beverage, snack, sauce or soup a flavor enhancement or modification of basic taste quality augmenting, enhancing or imparting quantity and concentration of at least one N-substituted unsaturated alkyl amide defined according to the structure:

R6)1-vN-<R2 where R1 = H or methyl;
R2 is selected from the group consisting of H, 01-04 alkyl, alkenyl and methylene;
R3 is selected from the group consisting of H, C1-C8 straight or branched chain alkyl, alkenyl, dienalkyl and phenyl;
or if R1 = H, R2 and R3 taken together can represent L' -1.
, cyclopropyl, cyclobutyl, cyclopentyl, cyclopentenyl, cycichexyl, or cyclohexenyl;
or if Ri - Me, R2 and R3 taken together can represent L' 1-1 or cyclopropyl, R4 is selected from the group consisting of C1-C4 alkyl;
R5 is selected from the group consisting of H, methyl or ethyl;
R6 is selected from the group consisting of H, methyl and ethyl;
R7 is selected from the group consisting of H, 01-09 straight or branched chain alkyl, alkenyl, alkyldienyl, acyclic or containing no more than one ring;
except for in the case of structure 4 when if R5 = H or methyl and R6 = H or methyl, R7 as described above and phenyl.
As used herein the most preferred compounds will be referred to hereinafter as dienalkylamides.

As used throughout the application, L' is understood to represent an alkene terminus as depicted in R2, R3, R7 and R8 with an attachment to the alpha carbon of the acid moiety in structures 1, 2, 3, 4, 5 and Formulae I and II set forth in the examples.
Our invention specifically relates to the novel compositions according to the Structure 3 above:
R1 R2 R3 R4 Rb R6 R7 __________________ Compound Double bond configuration as per drawing H cyclopropyl CH3 H H CH3CH2CH=CHCH2CH2 -.\ 0',--1 \
H cyclopropyl CH2CH3 H
H cH3cH2GiFicH2cH2 o A
---\- - N
\ ¨
H _________________________________________________________________________ cyclopropyl CH2CH2CH3 H H cH3cH2cH=--cHcH2cH2 vA
\
H
cyclopropyl Isopropyl H H CH3CH2CHHCH2CH2 _ N/ N
) H cyclopropyl t-butyl H H CH3CH2CH=CHCH2CH2 -1 _ H cyclopropyl Vinyl ________________________ H
H cx3cH2cHHcH2CH2 oH
_ H cyclopropyl Ally1 . H H
CH3CH2CH=CHCH2CH2 _ \
--\-1-/ N
\ -----=_-H cyclopropyl CH2 H -H cH3cH2cH=cHcH2cH2 0, Cyclo-A
propyl 1.
H cyclopropyl butyl H H
CH3 CH2CH=CHCH2CH2 µ.... _A
H cyclopropyl Sec-butyl H H CH3 CH2CH=CHCH2CH2 _ H cyclopropyl CH3 H H CH3CH2CH=CHCH2CH2 -''-'=N')Y
\

R R R R' R R* R7 Compound Double bond configuration as per drawing H cyclopropyl CH3CH2 ___________________________________ H H CH3 CH2CH=CHCH2 CH2 _ _ _______________________________________________________________________________ _____ H cyclopropyl CH3CH2CH2 H H CH3 CH2CH=CHCH2 CH2 _ -s.,-......."--,.......... ----, 1,1\JLT7 _ \
H cyclopropyl Isopropyl H H
cH3 cH2cH=cHcH2 CH2 -, .
o )----H cyclopropyl t-butyl H _________________ H
___________________ CH 3 CH2CH=CHCH2 CH2 =,, _ -'7-'1V)T7 ¨ __________________________________________________________ H cyclopropyl vinyl H H CH3 CH2CH=CHCH2 CH2 0 _______ _ .7wN)y _ _ H cyclopropyl allyl H H cH2 cH2cH=--cHcH2 cH2 o H cyclopropyl CH2 H H cH3 cH2cH=cncH2 cH2 o Cyclo-propyl ¨.
...
H cyclopropyl butyl H - H - CH3 CH2CH=CHCH2 H cyclopropyl Sec-butyl H H
CH3 CH2CH=CHCH2 CH2 ' ,,, 1 .), - _ H cyclopropyl CH3 H H ill 14\lsr H cyclopropyl CH3CH2 H
H o ,CH
H __________________________________________________________________________ cyclopropyl CH3CH2CH2 H H o CH
0 - (kr' H cyclopropyl Isopropyl H H
.--",-CH o Fe R2 R3 R4 R5 R6 R7 __________________ Compound Double bond configuration as per drawing _ H cyclopropyl t-butyl H H
,,-,CH o H cyclopropyl vinyl H
H ,,'ICH 0 -...-/I 0 hr:,.._.7 H cyclopropyl allyl H
H o -'---CH
¨
H cyclopropyl CH2 H
H o ''''''CH
Cyclo- 411 'Is' N)t'V
--.' propyl _ .
-H cyclopropyl butyl '1-1 H - /'CH o _______ H cyclopropyl Sec-butyl H H o -CH
)*
H ______________________________ cyclopropyl CH3 H H

o , I
H cyclopropyl CH3CH2 ________ H H

L, H cyclopropyl CH3CH2CH2 __ H - H

.)17N
ri H cyclopropyl Isopropyl H _ H ''CH

Y V
H ' cyclopropyl t-butyl H H r"'"CH

o .---,, P.' R2 R3 R4 R5 R6 R7 Compound Double bond configuration ,as per drawing _ H cyclopropyl vinyl H - H .-",CH

.-./' o tse.7 H cyclopropyl ally' H H --'--CH

....' NAV
i- -H cyclopropyl 0H2 H H v---CH
Cyclo- 40 .-.- o propyl -=,:
H cyclopropyl butyl H H .CH

."..:-.,' o N Ar _ H cyclopropyl Sec-butyl H H ' -'-'''CH

-.,.) 0 --õ,) _ .
H cyclopropyl CH3 Me H
1111 = tr jrzo H cyclopropyl - CH3CH2 Me H
1111 o 411 -' N17f H cyclopropyl CH3CH2CH2 Me - H
110 is tsavo .
, H cyclopropyl Isopropyl Me ___________ H
110 o ,31.).:LT7 H cyclopropyl t-butyl Me H
411 o N'1 -H cyclopropyl vinyl Me H

_______________________________________________________________________________ ____ el L:1----='Y

R R RR' R R* R7 Compound Double bond configuration as per drawing H cyclopropyl allyl Me H

4/0 õ N)LT7 (\
H cyclopropyl CH2 Me H
Cyclo-propyl H cyclopropyl butyl Me H

H cyclopropyl Sec-butyl Me H

NA,7 <-1 H cyclopropyl CH3 Me H

N1-v H cyclopropyl CH3CH2 -Me H

.) H cyclopropyl CH3CH2CH2 -Me H

N1,v H cyclopropyl Isopropyl Me -H
/1\
H cyclopropyl t-butyl Me H

Niv H cyclopropyl Vinyl Me H
Nlv R1 R2 R3 R4 Rb R6 R7 _________________ Compound Double bond configuration ,as per drawing H cyclopropyl Allyl Me H
Si 0 ) _ H cyclopropyl CH2 Me H
Cyclo-lel 0 _ Propyl *
H cyclopropyl Butyl Me H

- tsiKv ) ) 40H cyclopropyl Sec-butyl Me H 5 _ - NI-Icy c) H cyclopropyl -CH3 Me H .-%' NIIIT7 I
H cyclopropyl -CH3CH2 Me H

0 rji*o , H
cyclopropyl CH3CH2CH2 Me H o JY
.
_ H cyclopropyl Isopropyl Me - H

H cyclopropyl t-butyl Me H

o H cyclopropyl vinyl Me H
110 .
o Niõ)__z_Y' H cyclopropyl allyl -Me ' H

o ei N)Y
¨

R1 ' R2 R3 R4 R5 - R6 R7 ___________________ Compound Double bond configuration ,as per drawing H cyclopropyl CH2 Me - H o Cyclo-410 el propyl '\f') H ____________________________________ cyclopropyl -butyl Me H

qi H __________________________________________ ' cyclopropyl Sec-butyl -Me - __ H

o Op w&T/
H ____________________________________ cyclopropyl CH3 _____________________________________ H Me !
_ H __________________________________________ cyclopropyl -CH3CH2 __ -H Me NII
_______________________________________________________________________________ ____________ _ H __________________________________________ -cyclopropyl -CH3CH2CH2 -H Me -o H __________________________________________ cyclopropyl 'isopropyl -H Me o H __________________________________________ cyclopropyl t-butyl H Me ______________________ .
.---...õ
H __________________________________________ cyclopropyl vinyl __ H Me H __________________________________ cyclopropyl allyl __________ 11-1 Me 110 lb o Z\

RI R2 R3 R4 R5 R6 R7 __________________ Compound Double bond configuration as per drawing H cyclopropyl CH2 H Me Cyclo-Pr opyl \-() _ H cyclopropyl butyl H Me Si is 0 .
r---H cyclopropyl Sec-butyl -H - Me ''' NVJIN-7 H cyclopropyl CH3 Me H CH3 CH2CH=CHCH2CH2( > _ I
I
H cyclopropyl CH3CH2 Me H
CH3CH2CH=CHCH2CH2 H cyclopropyl CH3CH2CH2 Me H
CH3CH2CH=CHCH2CH2 0H
----\¨jr-r=<----N
- -H cyclopropyl isopropyl Me H
cH3CH2CH=CHCH2CH2 oH
H cyclopropyl t¨butyl Me H
CH3CH2CH=CHCH2CH2 ( c\____A
H cyclopropyl vinyl Me H cH3 cH2cH=cHcH2 cH2 _ .
H cyclopropyl allyl Me H CH3CH2CH=CHCH2CH2 C%--A
N
K---r---H cyclopropyl CH2 Me H CH3CH2CH=CHCH2CH2 C%--A
Cyclo-¨\¨fj propyl , H cyclopropyl butyl Me H CH3CH2CH=CHCH2CH2 0 R1 R2 R3 R4 Rb R6 R7 __________________ Compound Double bond configuration as per drawing _ _ H cyclopropyl Sec-butyl Me H cH3 CH2CH=CHCH2 CH2 / O\ fl ----"---H cyclopropyl CH3 Me H CH3 CH2CH=CHCH2 CH2 I
H cyclopropyl CH3CH2 Me H CH3 CH2CH=CHCH2 CH2 0 -', N)LT7 ) H cyclopropyl CH3CH2CH2 Me H
0-12 cH2cH-cHcH2 cH2 o -..
_ H cyclopropyl isopropyl Me H cH3 cH2cH=cHCH2 CH2 0 .
..-...'-'''N'i*
)\
, H cyclopropyl t-butyl Me H CH3 CH2CH=CHCH2 CH2 ' \

Z\
H cyclopropyl vinyl Me H cH2 cH2cH-cHcH2 cH2 o.
,,..
H cyclopropyl allyl Me H
cH3 cH2cH=cHcH2 CH2 o -, H cyclopropyl CH2 Me H
CH3 CH2CH=CHCH2 CH2 o Cyclo-propyl H cyclopropyl butyl Me H ' CH3 CH2CH=CHCH2 CH2 . _ H cyclopropyl Sec-butyl Me H CH3 CH2CH=CHCH2 CH2 ../4 __ H cyclopropyl CH3 H H
lo N,J,,c7 _ . _ H cyclopropyl CH3CH2 H H

40 ).J.LT/

R1 R2 R3 R4 R6 R6 R7 Compound Double bond configuration , as per drawing . _ H cyclopropyl CH3CH2CH2 H H
1110 o H cyclopropyl isopropyl 'H -H
= 0 X
H cyclopropyl t-butyl -H H ' 111 o 'H cyclopropyl vinyl H __ H
. o . N)Y
-H cyclopropyl ' allyl H H
Si 0 ...;} ___) H cyclopropyl CH2 H H 0 _ Cyclo-propyl 0 -s _ H cyclopropyl butyl H -H
lel o H cyclopropyl Sec-butyl H H

Op N)LT7 _1 _ r _ H cyclopropyl -CH3 H H
110 010 o NiLT7 I
_ H cyclopropyl -CH3CH2 H 'H
Pill 410 o _, .....' NAV
- _ H cyclopropyl CH3CH2CH2 H H
40 410 o _ N)Y

R1 R2 Ra R4 R5 R6 R7 Compound Double bond configuration i as per drawing .
_ H cyclopropyl isopropyl H H
:2c-iy H cyclopropyl t-butyl H H
= ,,,,,õ
.4\
H cyclopropyl vinyl -H H
= 410 H cyclopropyl allyl -H H

¨.) .
H cyclopropyl CH2 H H ' Cyclo-Si 40 propyl H cyclopropyl butyl H H

- N) H cyclopropyl Sec-butyl H - H
el 0 NJY
*
Me Me CH3 H Me (CH3)2C=CHCH2CH2 o I
Me Me CH3CH2 H Me (CH3)2C=CHCH2CH2 o rs4'i<
) ¨
Me Me CH3CH2CH2 H Me (CH3)2C=CHCH2CH2 o .

Ri R2 R3 R4 Rb R6 R7 Compound Double bond configuration as per drawing _ _______________________________________________________________________________ ______ Me Me isopropyl H Me (CH3)2C=CHCH2CH2 o '4)<
-'-' ._ .
Me Me t -butyl H Me (CH3)2C=CHCH2CH2 o -'.---=Thv'K<
---)\
Me Me vinyl H Me (CH3)2C=CHCH2CH2 o WN'l -----i"
________________ -,-_________________________________________________________________ .
- Me Me allyl H Me (CH3)2C=CHCH2CH2 o )1.,,l<
õ..,..... j -Me Me CH2 H Me (CH3)2C=CHCH2CH2 o Cyclo-N
propyl \I-1 Me Me butyl H Me - (CH3)2C=CHCH2CH2 o _ _ Me Me Sec-butyl H - Me (CH3)2C=CHCH2CH2 o --\-) _ Me Me CH3 H Me (CH3)2C:CHCH2CH2 N-k-<
I
Me Me CH 3CH2 H Me (CH3)2C:CHCH2CH2 o .
_ Me Me CH 3 CH2 CH2 H Me (CH3)2C:CHCH2CH2 ---1%------LI 0 rj _ Me Me isopropyl H Me (CH3)2C:CHCH2CH2 -. 0 :a<
Me Me t -but yl H _________________ Me (CH3)2C:CHCH2CH2 ,--L.,--`-- o NI)Li<
---) R-3- R2 R3 R4 Rb R6 R7 Compound Double bond configuration , as per drawing . - õLi, ,,,,,..,,, _ Me Me vinyl H Me kL,n3)2k_,A_A-A,n2k-r-i2 o NN)L<
,-J
_ Me Me ally]. H Me (CH3)2C:CHCH2CH2 TIT( - Me Me CH2 H Me (CH3)2C:CHCH2CH2 .
Cyclo- ,, 0 propyl N
Me Me butyl H Me (CH3)2C:CHCH2CH2 Me - Me Sec-butyl H Me (CH3)2C:CHCH2CH2 ______________________________ .
jrki<
_ Et ' H 0H3 H Me (CH3)2C=CHCH2CH2 o _________ _ i - - -Et H CH3CH2 H Me (CH3)2C=CHCH2CH2 -.
Et H CH 3 CH2 CH2 H Me (CH3)2C=CHCH2CH2 o _________ _ \ N-) _ -Et H isopropyl H Me (CH3)2C=CHCH2CH2 ')\
- _______________________ Et H t -butyl H Me (CH3)2C=CHCH2CH2 o _ --, 4\
_ _______________________ Et H vinyl H Me (CH3)2C=CHCH2CH2 o _ - _______________________ _ Et H allyl H ' Me (CH3)2C=CHCH2CH2 o ¨
Et H CH2 H Me (CH3)2C=CHCH2CH2 - __________________ o Cyc 1 o -Isrk-propyl .-) -_______________________________________________________________________________ ______ R R R R R IV R7 Compound Double bond configuration as per drawing Et H butyl H Me (0-13)2C=CHCH20-12 o _ r , Et H Sec-butyl H Me (CH3)2C=CHCH2CH2 o N.
----\
. -Et H CH3 H Me (CH3)2C=CHCH2CH2 _ -'''''''''= o N.N.11....
T
Et H CH3CH2 H Me (CH3)2C=CHCH2CH2 ) Et H CH 3 CH2 CH2 H Me (CH3)2C=CHCH2CH2 .

rN
,) -Et - H isopropyl H Me (CH3)2C-CHCH2CH2 o -Et H t -butyl H Me (CH3)2C=CHCH2CH2 -7----'`'' o _ Et H vinyl H Me (CH3)2C-CHCH20-12 Ni....,.,.__ _ Et H allyl-H Me (CH3)2C=CHCH2CH2 "- o NN) _ Et H CH2 H - Me (CH3)2C=CHCH2CH2 _ Cyclo-'''`. o propyl N
Et H - butyl H Me (CH3)2C=CHCH2CH2 ri--N-1 R' R2 R3 R4 Rb R6 R7 ________________________ Compound Double bond configuration as per drawing - T__, ' õ,, __________________________________________ - / ru \ r, rvuhr-q3 ',LT -Et H Sec-butyl n vie \-i.3,2,7-,.....2-2 .7-..,..1 o ¨7j Me H CH3 'Me H ' ______________________________________________ I.
o 410 N)L-I
.
Me H ' C1-i3CH2 Me H -o I
_ _______________________________________________________________________________ __ Me H CH3CH2CH2 -Me H
o U , N''' Me H _________________________ isopropyl Me H

o 11 , Me H t-butyl Me H

o el N) ...-i ¨ , ________________________ Me H vinyl Me __ H
NO
o Me H allyl Me __ H

o ______ 410 , N)L"'' Me H CH2 Me H
o Cyclo-propyl . _ ____________________________________________________ Me H butyl Me H

o 40, N) .-.I.s._ Me H sec-butyl Me H

o _______ lei Isi'j Me . H CH3 Me __ H _______________ = 0 ____ _ .....
N)(_, .
_______________________________________________________________________________ _ _ 111 R2 R3 R4 R6 R6 R7 Compound Double bond configuration as per drawing Me H CH3CH2 Me H

L, Me H CH3CH2CH2 Me H

Me H isopropyl Me H

Me H t-butyl Me H

\ N
_ -Me H vinyl Me H

Me H allyl Me H

N
Me H CH2 Me H
Cyclo-propyl Me H butyl Me H

Me H Sec-butyl Me H

N

121 R2 R3 R4 R5 R6 R7 Compound Double bond configuration as per drawing Me H CH3 H Me ___________ o _______________________________________________________________________________ ______ _ Me H CH3CH2 H Me III 0 N( )U
Me H CH3CH2CH2 H Me Me H isopropyl H Me _____ o ______ N'i ./c _ o Me H t-butyl H Me 'Nr.r,l-J., ---...--õõ--- ----_ Me H vinyl H Me _________ o ____ -,, Me H allyl H Me _________ o ______ --...
A.........

"1-___ _ _______________________________________________________________________________ _____ Me H CH2 H Me Cyclo-411 sej i)N )- i propyI
, _______________________________________________________________________________ ______ Me H butyl H Me --.
__ Me H Sec-butyl H Me o _ 0 ,..._.) _ Me H CH3 H Me -,...
7....u......õ, Me H CH3CH2 H Me ________ 410 o , RI- R2 R-3 R4 R5 R6 R7 Compound Double bond configuration as per drawing _ Me H CH3CH2CH2 H Me ________________________________ \ N
\
\
_ _______________________________________________________________________________ _____ Me H Isopropyl H Me 4111 el 0 ,....
N.).,...õ--_ .
_ Me H t-butyl H Me II = 0 ---- \
Me H Vinyl H Me _____________________________________ 41 1101 o ---.
...1t..õ..-t=
Me H Allyl H Me __________ lel 40 0 ...
, _______________________________________________________________________________ _____ .
_ .
Me H CH2 H Me Cyclo-Propyl N
..----1 - - _ Me H Butyl H Me .....
N)L-' \
\
Me H Sec-butyl H Me ______ ).---H H CH3 Me H _ ____________________ o fi-J1-H H CH3CH2 Me __ H
lel o Njj' RI Fe R? p,:: Rb R6 R7 __________________ Compound Double bond configuration as per drawing _ H H CH3CH2CH2 Me H
14 _ 0 ___ \
, , H H Isopropyl Me H
lel o 0 N-) ---'c H H t-butyl 'Me H
NO 010 , NA.
/)\
H H _______ Vinyl __ Me H

o ,J

Tr=
i .
H H Allyl Me H
el o __ H----o H H _ CH2 Me H
Cyclo-Propyl H H _______ Butyl __ Me H
lel o ______ rq-J

H H Sec-butyl Me H
.,1:1' _ . 10 H H CH3 __________________________ Me H
_________ 410 o __ i _ H H CH3CH2 Me H _ NO
410 o -..
WJ.L.
) _ H H CH3CH2CH2 Me H

IN o H _________________________________ H __ Isopropyl Me H

410 o W,11 /K
_ __________________________________________________________ Rl R2 R3 R4 R5 R6 R7 __________________ Compound Double bond configuration as per drawing . ._ H H t-butyl Me H

./\
-1411 0, o 410 iol 0 .J., NL___,.õ
_ .
, Cyclo-Propyl N

lel 40 , _ el 0 o N).(, * .
= 0 ...i.
=
iii .
H H CH3CH2 'H Me 0, N5k _ H H CH3CH2CH2 H Me ei ,, Na0 . H H Isopropyl H Me - .
0 .
H H t-butyl H Me el et Ri- R2 R3 R4 Rb R6 R7 Compound Double bond configuration as per drawing . _ o H H Vinyl H Me Iiil el rsiL_ ¨
H H Allyl H Me o H H CH2 H Me o Cyclo-. Ni-Propyl H H _______ Butyl __ H ________________ Me 410 ' )' o ,J-H H Sec-butyl H Me _______________________________ H
-, _ H H CH3 H Me 110 o -, )-L., _ H H CH3CH2 H Me II
410 o ) _ _ _ H H CH3CH2CH2 H Me OOP

õ.
NA.
(õ.
. , H - H Isopropyl H Me 410 o W,k , H H t-butyl H Me 410 o -,. W.11õ

H H __________________________ Vinyl H Me __________________________________ PIO
110 o -, ).
NI, .

Fe R2 R3 R4 R-5 R6 R7 Compound Double bond configuration as per drawing _ - .
H H Al lyl H Me el 0 o \ N)-.
, , H H. CH2 H Me e Cyclo-l Propyl _ _ H H Butyl H Me Si \---\--__ _ -_ H H Sec-butyl H Me Si t 1 ----(j H H CH3 Me H
CH 3 CH2CH=CHCH2 CH2 _../
/-----/ \ --N
-H H CH3CH2 Me H CH3 CH2CH=CHCH2 C..0 -----\ -7-1-(---0 \
, H H CH3CH2CH2 Me H CH3 CH2CH=CHCH2 CH2 _ /¨/---( 0-\ _ H H Isopropyl Me H oil cH2cH=clicH2 cH2 , (1)\
-I, --\___/---/ \--N
)-, H H t-butyl Me H CH3 CH2CH=CHCH2 CH2 ----\_/-1 N
H H Vinyl Me H CH3 CH2CH=CHCH2 CH2 0___ N
L-H H Al 1 yl Me H cH3 cH2cH---04012 cH2 ,.j _ , H H CH2 Me H cH3 cH2cH=cHcH2 cH2 i_ Cyclo----/
N
Propyl --R1 R2 R3 R4 Rs R6 R7 Compound Double bond configuration as per drawing _ H H Butyl Me H CH3 CH2CH=CHCH2 CH2 o /--/¨(--r--\-- \
\
- _ H H Sec-butyl Me H
CH3 cH2CH=cHCH2 CH2 ( o____ --\\_/---/ \---N
\----( ._ H H CH3 Me H CH3 CH2CH=CHCH2 CH2 õ

I
__ _ _____________________________________________________ CH3 CH2CH=CHCH2 CH2 H H CH3CH2 Me H
o ) _ __________________________________________________________ 3 = õ
H H CH3CH2CH2 Me H
CHCH2CHCHCH2 CH2 o -''----"-----nr"-IC
H H Isopropyl Me H CH3 CH2CH=CHCH2 CH2 õ

-_ CH3 CH2CH=CHCH2 CH2 õ
H H t-butyl I Me H
o )\----H H Vinyl Me H cH3 cH2cH=CHCH2 CH2 -'-.-"-M\1)4'=
_ _ I-I H Ally' Me H cH3 CH2CH=CHCH2 CH2 õ

H H CH2 Me H CH3 CH2CHHCH2 CH2 õ

Cyclo--Wts1) Propy 1 /-/
_ H H Butyl Me H
CH3 CH2CH=CHCH2 CH2 o \
\
H H Sec-butyl Me H
CH3 CH2cH=cHcH2 cH2 o ----o Me H CH3 H H --7-CH

R1 R2 P? R4 Rb R6 R7 ___________________________ Compound Double bond configuration as per drawing Me H CH3CH2 H H
Me H CH3CH2CH2 H H
/'''CH ___ o 010 L, _______________________________________________________________________________ _______ _ Me H Isopropyl H H
Me H t-butyl H H
'.../H
.
_______________________________________________________________________________ ______ .
Me H Vinyl H H
0, tsl'j Me H Allyl H H
o -Me - H CH2 H H 'CH o Cyclo- 0 N) ../
Propyl Me H Butyl H H
_ Me H Sec-butyl H H CH
.
.
-Me H CH3 H H

='-:./j o i Me H CH3CH2 H H ''CH

'..'=/ o --...
)1,.....õ, N.
I
_ _______________________________________________________________________________ ______ Me H CH3CH2CH2 H H CH
o s=-..
N....II,,...-- re R2 R3 - R4 R5 - R.6 ___________ R7 Compound Double bond configuration as per drawing , _ _______________________________________________________________________________ ______ Me H Isopropyl H H

...- o r-J\
Me H t-butyl H H --"--CH

/) _ _ Me H Vinyl H H _ CH

Nt,õ____ .
_______________________________________________________________________________ ______ _ Me H Allyl H H '''CH
_ _______________________________________________________________________________ ______ Me H CH2 H H

Cyclo-Propyl N
,,r Me H Butyl H H -'''''CH

\
\
_ Me H Sec-butyl H H
r'''''"CH /'==-=:) I
'--- o --.-W1L' o H H CH3CH2 H H '''CH
- ____________________________________________________________________________ o wiL

RI R? R.3 R4 R,5 R! R7 _________________ Compound Double bond configuration as per drawing .
_ H H Isopropyl H H
-''''''CH
o N) H H t-butyl H H
''''''CH o N
H H Vinyl H H
H H Allyl H H
----''CH o './' 4101 rsr'k ''''''CH o N
Cyclo- 410 '-,-' Propyl H H Butyl H H
L, H H Sec-butyl H H
W,k '-...,J
---_ ..,,, 0 , W1, H ' H CH3CH2 H H (CH

, W1õ
_ H H CH3CH2CH2 H H '''''''CH

o WJL
H H Isopropyl H H -CH

..,...- 0 , W1, A

Ri= R2 le R4 Rb R6 R7 Compound Double bond configuration as per drawing , _ H H t-butyl H H

\ N)1, I
1\
_ H H Vinyl H H ''/'''CH
IP
-,-.- 0 NIL.,, H - H Allyl H H vCH
IP
N)-L
H H CH2 H H .-'---.CH
cyclo- ID
-----, o propyl ")7 _ H H Butyl H H 7--CH

\ N
H H Sec-butyl H H '''''CH

,,- .
\ N.J.L, -----(\) ______________________________________________________________________________ _ Me Me 0H3 H H --CH
- _ Me - Me CH3CH2 H H
C
_ . _ o Me Me CH3CH2CH2 H H

--.,.-_ o Me Me Isopropyl H H 7''''CH
-o Me Me t-butyl H H ''''''CH
NLT( -_______________________________________________________________________________ ______ R1 R2 R3 R4 R6 R6 R7 Compound Double bond configuration as per drawing _ . .
, 0 Me Me Vinyl H H ''CH
N),<
_ , Me Me Allyl _ H H rCH
N)0C( Me Me CH2 H H -CH o Cyclo-',-Propyl _ Me Me Butyl H H ,-''''CH 0 /
Me Me Sec-butyl H H 1 CH -, 0 Me Me CH3 H H ''''CH 0 1..õ...-N,,...., I
Me ' Me CH3CH2 H H ''''CH 410o '------ NI-LH<
) _ Me Me CH3CH2CH2 H H -'''''CH 010(131 , Me Me Isopropyl H H /-"-CH 0 9 r;c4)tl<
--_______________________________________________________________________________ _____ Me Me t-butyl H H ''..CH 40 o .

Me Me Vinyl H H "CH
Me Me Allyl H H -CH 410 o -',-\Nõ...._iyit-i<
_ _______________________________________________________________________________ ______ Me Me CH2 H H '''''CH 40 ,, o Cyclo- N).
-,-Propyl V) , R1 R2 R3 R4 R5 - Rb R7 Compound Double bond configuration as per drawing Me Me Butyl 11 H 7'--CH 410 o 71)H<
_ Me Me Sec-butyl H H CH 0 ,,,, 0 Y
_ Me H Et CH3 H Me (CH3)2C=CHCH2CH2 o N'IC
I
.-_ Me H Et CH 3 CH2 - H
Me - (CH3)2C=CHCH2CH2 o Me H Et CH 3 CH 2 CH2 H Me (CH3)2C=CHCH2CH2 o _ ,--------Me H Et Isopropyl H Me (CH3)2C=CHCH2CH2 o _ ----/
- - _ Me H Et t -butyl H
Me (CH3)2C=CHCH2CH2 0 NiL-7 _ _ Me H Et Vinyl H Me (CH3)2C=CHCH2CH2 o Me H Et Allyl H Me (CH3)2C=CHCH2CH2 o _ ....-L^,.....----------_ Me H Et CH2 H Me (CH3)2C=CHCH2CH2 o .
Cyclo- ...--------,.......----- N-11-----Propyl ,v) _ Me H Et Butyl H Me (CH3)2C=CHCH2CH2 o 'N) rf Me H Et Sec-butyl H Me (CH3)2C=CHCH2CH2 o -J --_ Me H Et - CH3 H Me (CH3)2C=CHCH2CH2 _ N
I

R1 re R3 R4 __________ -5 6 R R R7 Compound Double bond configuration as per drawing Me H ' Et CH3CH2 H Me (CH3)2C=CHCH2CH2 _ ----v% o \
_ Me H Et CH3CH2CH2 H Me (CH3)2C=CHCH2CH2 Me H Et Isopropyl H ' Me -(CH3)2C=CHCH2CH2 o N-L--Me H Et t-butyl H - M= e -(CH3)2C=CHCH2CH2 _ -"-'"----'1 o ' Me H Et Vinyl H Me - (CH3)2C=CHCH2CH2 o Me H Et - Allyl H ' M= e (CH3)2C=CHCH2CH2 _ ,,,,,-,.-= 0 Cr1).
Me H - Et CH2 H Me (CH3)2C=CHCH2CH2 Cyclo- ..'-.---- o propyl isil.J.Lõ( 'I---_ Me H Et butyl H Me (CH3)2C=CHCH2CH2 .),.-o r4-JL------__/---/
Me H ' Et ' Sec-butyl -H .
Me (CH3)2C=CHCH2CH2 ---_,--,,,, o NN) --H cyclopropyl 0H3 -H Me (CH3)2C=CHCH2CH2 o *
I
H cyclopropyl CH3CH2 H
' M= e (CH3)2C=CHCH2CH2 o .....' ,,r7 I

Rl R2 R3 R4 Rs R6 R7 Compound Double bond configuration ,as per drawing H cyclopropyl CH 3 CH2 CH2 H Me (CH3)2C=CHCH2CH2 H cyclopropyl Isopropyl H Me - (CH3)2C=CHCH2CH2 H cyclopropyl t -but yl H Me (CH3)2C-cHCH2CH2 H cyclopropyl Vinyl H Me (CH3)2C=CHCH2CH2 H cyclopropyl All yl H Me (CH3)2C=cHCH2CH2 H cyclopropyl CH2 H Me (CH3)2C=CHCH2CH2 Cyclo-Propyl H cyclopropyl Butyl H Me (CH3)2C=CHCH2CH2 H cyclopropyl Sec-butyl - Me (CH3)2C=CHCH2CH2 H cyclopropyl CH3 H Me (CH3)2C=CHCH2CH2 o H cyclopropyl CH3CH2 H Me (CH3)2C-H cyclopropyl CH3CH2CH2 H Me (CH3)2C=CHCH2CH2 o "ILT/
H cyclopropyl Isopropyl H Me (CH3)20=CHCH2CH2 N. 0 r4A-c7 R1 R2 R3 ____ RR5 R6 R7 Compound Double bond configuration as per drawing _ H cyclopropyl t-butyl H Me (CH3)2C=CHCH2CH2 i N)Y
/.=
- -' H cyclopropyl Vinyl H Me (CH3)2C=CHCH2CH2 i tq)Y
-.:----i--_______________________________________________________________________________ ______ H cyclopropyl Ally' H - Me (CH3)2C=CHCH2CH2 _ H cyclopropyl _ CH2 H Me (CH3)2C=CHCH2CH2 ,)-=,õ,,, _ Cyclo- 0 propyl NN)*
H ____________________________________________________ cyclopropyl ____________________ butyl H Me (CH3)2C=CHCH2CH2 _ NN)Y---__/"--/
_ H cyclopropyl Sec-butyl H Me (CH3)2C=CHCH2CH2 -..,--. 0 NJ'IY
----\) H Me CH3 H
Me (CH3)2C=CHCH2CH2 o .------,.. ---/Ly----_ _ H Me __________________ ' CH3CH2 H Me (CH3)2C=CHCH2CH2 o 1 -!>4' I
, _______________________________________________________________________________ ______ H Me CH3CH2CH2 H
Me - (CH3)2C=CHCH2CH2 o _ -,.
r-N-1----' ---/
H Me Isopropyl H Me (CH3)2C=CHCH2CH2 o ---/
H Me t-butyl H
' Me (CH3)2C=CHCH2CH2 9 '--WN-) /
- H Me Vinyl H Me (CH3)2C=CHCH2C1-12 o ________ N)Y--'iJ-_ H Me Allyl H
Me (CH3)2C=CHCH2CH2 o --.

- RI- R2 R3 RR5 R6 ________________ R7 Compound Double bond configuration as per drawing Me CH2 H Me (CH3)2C=CHCH2CH2 Cyclo-Pr opyl .V) Me Butyl H Me (CH3)2C=CHCH2C1-I2 Me Sec-butyl H Me (CH3)2C=CHCH2CH2 0 Me CH3 H Me (CH3)2C=CHCH2CH2 o Me CH3CH2 H Me (CH3)2C=CHCH2CH2 s'= 0 ( Me CH 3 CH 2 CH2 H Me (CH3)2C=CHCH2CH2 Me Isopropyl H Me (CH3)2C=CHCH2CH2 t4)*
_ _ Me t -butyl H Me (CH3)2C=CHCH2CH2 N. 0 N
Me Vinyl H Me (CH3)2C=CHCH2CH2 o NN
-_______________________________________________________________________________ ______ Me Al lyl H Me (CH3)2C=CHCH2CH2 N. 0 Me CH2 H Me (CH3)2C=CHCH2C1-12 Cyclo-propyl R1 R2 R3 R4 R5 R6 R7 Compound Double bond configuration as per drawing H Me butyl H Me (CH3)2C=CHCH2CH2 _ ,7 o rq)*-__/----/
_ H Me Sec-butyl H Me (CH3)2C=CHCH2CH2 I
_ 5C' H CH3 H Me (CH3)2C=CHCH2CH2 o ,--teN71 I

Me (CH3)2C=CHCH2CH2 ou I
. , H CH 3 CH2 CH2 H Me (CH3)2C=CHCH2CH2 o _ H
Isopropyl H Me (CH3)2C=CHCH2CH2 o N

_ H t -butyl H Me (CH3)2C=CHCH2CH2 on ,?
7' H
,--te Vinyl H Me (CH3)2C=CHCH2CH2 o \ N)-H Al 1 yl H
Me (CH3)2C=CHCH2CH2 o ---__,) . .
_____________________________________________________ H CH2 H Me (CH3)2C=CHCH2CH2 o ,--te Cyclo- --.
,V,...,....õ
N
Propyl V) _ _______________________________________________________________________________ _____ H Butyl H
Me (CH3)2C=CHCH2CH2 o r H- Se c-but yl H Me (CH3)2C=CHCH2CH2 o '-i' '-,....-----N)-1,--= -...õ
----) H ___. CH3 H Me (CH3)2C=CHCH2CH2 I
_ _______________________________________________________________________________ ______ R-1 R2 R3 R4 R5 Rb R7 Compound Double bond configuration as per drawing _ Me (CH3)2C=CHCH2CH2 _ /I
\
- _ H CH 3 CH2 CH2 - H Me - (CH3)2C=CHCH2CH2 I, ''-v------- o )-,,N,11-_ ,---õ, ( - H
''' I s op r op yl H Me (CH3)2C=CHCH2CH2 _ H
t -but y 1 H Me (CH3)2C=CHC1-12CH2 o N.N.A.....-/-'=
-H
"''' Vinyl H Me (CH3)2C=CHCH2CH2 _ o j, H
,' Allyl H Me (CH3)2C=CHCH2CH2 _ .,) - ' CH2 H Me (CH3)2C=CHCH2CH2 .
H
Cyclo- "- o propyl Y
_ H
"' butyl H Me (CH3)2C=CHCH2CH2 '-1 N
---/----/
- -_ H -=-te Sec-butyl H Me (CH3)2C=CHCH2CH2 N. -L...., N
-----H
CH3 H Me (CH3)2C=CHCH2CH2 o H
)- CH3CH2 H Me (CH3)2C=CHCH2CH2 o I

Ri R2 R3 R4 ________________________________________________________________ Rb R6 R7 Compound Double bond configuration , as per drawing _ -H
CH 3 CH 2 CH2 H Me (CH3)2C=CHCH2CH2 o _.r..N
_ _ - -_ H
Isopropyl H Me (CH3)2C=CHCH2CH2 .._3/ 9 /
H
)..' t -butyl H Me (CH3)2C=CHCH2CH2 1 o õ1 .....1.,.., N
7( _ H
Vinyl H Me (CH3)2C=CHCH2CH2 /
--..
H
Allyl H Me (CH3)2C=CHCH2CH2 o --.
-..--,-õ) _ Me s 22 H

Propyl H 1 C=CHCH CH
(CH 3, 2 v) 9 i _ Cyclo--H
Butyl H Me (CH3)2C=CHCH2CH2 o /
-----_--pN) r _ )H Sec-butyl H Me (CH3)2C=CHCH2CH2 o _ _ H
CH3 H Me (CH3)2C=CHCH2CH2 I
_ H
CH3CH2 H me (CH3)2C=CHCH2CH2 C
_ H
CH 3 CH2 CH2 H Me (CH3)2C=CHCH2CH2 -.... .-IL....õ-H
Isopropyl H Me (CH3)2C=CHCH2CH2 R' R2 R3 R4 R5 R6 R7 Compound Double bond configuration as per drawing t -butyl H Me (CH3)20=CHCH2CH2 Li /^
H
Vinyl H Me (CH3)2C-CHCH2CH2 Al lyl H Me (CH3)2C=CHCH2CH2 /

y H Me (CH3)2C=CHCH2CH2 C clo-/
propyl butyl H Me (CH3)2C=CHCH2CH2 N
Sec-butyl H Me (CH3)2C=CHCH2CH2 H cyclopropyl CH3 H H CH3(CH2)4CH=CHCH2 CH2 /\.,-"\ 0 N)Y
H cyclopropyl CH3CH2 H
H CH3(CH2)4CH=CHCH2 Cl-I2 0 N-Jy R R KR' R R7 Compound Double bond configuration as per drawing H cyclopropyl t-butyl H H
CH3(CH2)4CH=CHCH2 CH2 H cyclopropyl Vinyl H H
CH3(CH2)4CH=CHCH2 CH2 H cyclopropyl Ally1 H H
CH3(CH2)4CH=CHCH2 CH2 H cyclopropyl CH2 H H CH(CH2)4CH=CHCH2 Cyclo-Propy1 H cyclopropyl Butyl H H
CH3(CH2)4CH=CHCH2 CH2 1-1 cyclopropyl Sec-butyl H H CH3(CH2)4CH=CHCH2 CH2 N)Y
H cyclopropyl CH3 H H
CH3(CH2)4CH=CHCH2 CH2 H cyclopropyl CH3CH2 H H
CH3(CH2)4CH=CHCH2 CH2 o MNI)/

Rl R2 R3 R4 R5 R6 R7 _______________ Compound Double bond configuration as per drawing H cyclopropyl CH 3 CH 2 CH 2 H H
CH3(CH2)4CH=CHCH2 CH2 H cyclopropyl - Isopropyl H H
CH3(CH2)4CH=CHCH2 CH2 -H cyclopropyl t-butyl H H
CH3(CH2)4CH=CHCH2 CH2 ./\./"\

- - ________________________________________________________ H cyclopropyl Vinyl H H
CH3(CH2)4CH=CHCH2 CH2 H cyclopropyl Allyl H H
CH3(CH2)4CH=CHCH2 CH2 1\1) H cyclopropyl CH2 H H CH3(CH2)4CH=CHCH2 CH2 Cyclo-Propyl o \7) H cyclopropyl Butyl H H CH3(CH2)4CH=CHCH2 CH2 H cyclopropyl Sec-butyl H H
CH3(CH2)4CH=CHCH2 CH2 `- 0 R' R2 R3 R4 R5 R6 R7 _______________ Compound Double bond configuration as per drawing H cyclopropyl CH3 H ' Me 0 til)y , H - cyclopropyl CH3CH2 H _______ Me ________________ i'''CH ii= ,, ,i)y .71-,----_ H cyclopropyl CH3CH2CH2 H Me __ 0 ))y ___________ 'V-CH
_______________________________________________________________________________ ______ _ H cyclopropyl Isopropyl H Me "r'CH 9 ,7--/ 010 N)117 ---j\
_ H - cyclopropyl . t-butyl H Me -,7',CH o H cyclopropyl Vinyl H Me ,,,".CH o - Me ____________________________________________ _ H cyclopropyl -Allyl H
v'''CH o H cyclopropyl CH2 H Me 0 ._.r.xvo Cycl o----"s`-----Propyl N
H cyclopropyl Butyl H Me _.---,-1 0- N")7 r-j H cyclopropyl Sec-butyl ' H - Me *
H cyclopropyl - CH3 H Me SO

_ -H cyclopropyl CH3CH2 H Me SO
) Ri R-2 R3 R4 R R6 R7 ___________________ Compound Double bond configuration as per drawing H
_______________________________________________________________________________ _____ cyclopropyl CH3CH2CH2 H Me õõNAT7 H cyclopropyl Isopropyl H Me :1\1)Y' _ _______________________________________________________________________________ _____ H cyclopropyl t-butyl H Me , CH

Nj*
H ______________________________ cyclopropyl Vinyl ___________________________________ H Me NAV
H ______________________________ cyclopropyl Allyl _________ H Me NAV
H cyclopropyl CH2 H MeCH
Cyclo-Propyl 010 H cyclopropyl Butyl -H Me N AT/
_ .
H cyclopropyl Sec-butyl H Me N-ity R R RS R6 R7 _______________ Compound Double bond configuration as per drawing H cyclopropyl CH3 H Me Me 0 H cyclopropyl CH3CH2 H
Me Me 0 '=-='''..Thµr-ki7 ---) H cyclopropyl CH3CH2CH2 H
' Me ' Me o N).L.7 H cyclopropyl Isopropyl H Me __ Me ____ 0 _ ----c ---)\
H cyclopropyl Vinyl H
Me Me 0 ----'-)i)jr H cyclopropyl Allyl H
Me Me 0 _ __ _ ______________________________________________________ Cyclo-r,l'iC7 Propyl \rj __ _ tsl*
--rj H cyclopropyl Sec-butyl H Me Me o _ -----"N-J.L7 *
H _______________________________ cyclopropyl CH3 __________ H H _ r'''''CH
_ H cyclopropyl - CH3CH2 H H
Si '' teit7 / ..../1\
) H cyclopropyl - CH3CH2CH2 H - Ho _ H cyclopropyl Isopropyl H H
..,--CH o fr---R R RR' R R R7 Compound Double bond configuration as per drawing H cyclopropyl t-butyl H H
N
H ______________________________ cyclopropyl Vinyl H H

N'ILT/
H ______________________________ cyclopropyl Ally1 H H

õ) H cyclopropyl CH2 H H CH
Cyclo- 00 - NAT/
Propyl H cyclopropyl Butyl __ H H CH

_____________________________________________________________________________ fly H __ cyclopropyl Sec-butyl H H
N )C17 H cyclopropyl -CH3 -H H
- NIT/
H
_______________________________________________________________________________ _____ cyclopropyl CH3CH2 -H H

H ____________________________________ cyclopropyl CH3CH2CH2 H H

H cyclopropyl Isopropyl H HCH

)1).117 R R R It'R ¨I-- b R R7 Compound ' Double bond configuration as per drawing _ H cyclopropyl t-butyl H H
/....71`-. =0 N)ly _ _______________________________________________________________________________ ___ H cyclopropyl Vinyl H H
,-"-CH ____ =0 N)L17 H cyclopropyl Allyl H -1-1 ----,kiKr _____________________________ __ __________________________ H cyclopropyl 0H2 H H ''''CH
Cyclo-.-----./-\
Propyl =0 VI
H cyclopropyl Butyl H H
---------\ 010 o NA'V
----rj H cyclopropyl Sec-butyl H
H /."-CH
.------/\

NI"V
y , H ' H CH3 H Me __ ¨__¨ .
H H CH3CH2 H _ Me /-=`-..,/ 5) H H CH3CH2CH2 -H -Me -CH
ri , Rr R3 ------2 R4 ' R5 R6 R7 ______________ Compound R
Double bond configuration as per drawing o H H Isopropyl H Me __ CH
_____________________________________________________________________________ /L
1 ______________________________________ -_ H H t-butyl H Me CH
1õ
./''''.'=./ --)..7 _______________________________________________________________________________ _______ _ H H Vinyl H Me ''CH
010 NI' -..J
H H Allyl H Me )(, ..-/
S) _ H H CH2 H Me Cyclo-010 v) .--`-':.--Propyl , ___________________________________________________________ H H Butyl H Me ____________ --"--CH __ o _ __----_______________________________________________________________________________ -H H Sec-butyl H Me -_______________________________________________________________________________ _____ _ H H CH3 H Me ----N-CH
/..-../

H H CH3CH2 H Me SO
,.. W1, ) , H H CH3CH2CH2 H Me e , H H Isopropyl H Me 7"CH
Or o .)--- ___________________________________________________________ R R K R R R7 Compound Double bond configuration as per drawing t-butyl H Me -"CH
=0 N
Vinyl H Me So N
Allyl H Me _________ N
H H CH2 H Me Cyclo-Propyl N
V) Butyl H Me W1, Sec-butyl H Me _________________________________ N
_____________________________________ CH3 H H
N) CH3CH2 H ___ H

_______________________________________________________________________________ ______ CH3CH2CH2 H H _______ R R R R. R R.' R7 Compound Double bond configuration as per drawing ________________________________________________________________________ .
o H H Isopropyl H H
=-=%,. NO tj.,l -_ _______________________________________________________________________________ ______ H H t-butyl H H v'''''CH
is-o H H Vinyl H H -CH
o H H Allyl H H (CH
--,, _______________________________________________________________________________ _______ _ , Cyclo- 0 1\12 Propyl i o H H Butyl H H
\
o H H Sec-butyl H H
-k i ___________________________________________________________ _ I __ I
H H CH3 H H =CH
.---,=''1\ ill ) _ __________________________________________________________ =0 W,k H H Isopropyl H H ''CH
SO
`-.
N.JI

R1 R2 R3 R4 R5 R6 1(7 Compound Double bond configuration as per drawing _ H H t-butyl H H 7-CH
le o \ N,k _ H ' H Vinyl H H ''''CH
le 0 \ N,K
/J
H H Allyl H H --v'CH
SO
\ N

_ H H CH2 H H (CH
Cyclo-, Propyl o \ N)' Y
H H Butyl H H
So \ N)' /
/
_______________________________________________________________________________ ____ ___ _ H H Sec-Butyl H H ('-CH

\ N)-\) - _________________________________________ CH3 CH2CH=CHCH2CH2 Me H CH3 H H
¨ /
Me H CH3CH2 H H CH3 CH2CH=CHCH2CH2 0, __ /
) CH3CH2CH=CHCH2CH2 Me __ - H _________________________ ' CH3CH2CH2 H H
, /
--\___/-2--\--N
_ , Me H Isopropyl H H CH3 cH2CH-cHCH2 CH2 0¨ /
\ _ , __________________________________________________________ RI- R2 R3 R4 Rb Rb R7 Compound Double bond configuration as per drawing _ _______________________________________________________________________________ _____ _ Me H t -butyl H H CH3CH2CHHCH2CH2 O\ /
"--\_, ---)--_ Me H Vinyl H H CH3 cH2cHHCH2 cH2 _ o, / __ -_ Me H Allyl H H CH3CH2CHHCH2CH2 % if _ \
- ______________________________________________________ Me H CH2 H H cH3 cH2cH=cHCH2 cH2 Cyclo-\-N
---\ -7--/
propyl _ _______________________________________________________________________________ _____ _ cH3 cH2cH=cHcH2 cH2 o /
Me ________ - H Butyl H H
) Me H Sec-butyl H
H cH3 cH2ca=cHcH2 cH2 o I
_______________________________________________________________________________ ______ Me H CH3 H H cH3 cH2cHHcH2 cH2 ¨\/
o \
r _____________________________ _ Me ,. _ H CH3CH2 H H cH3 cH2cHHcH2 cH2 -N
) _ _ Me H CH3CH2CH2 H H
cH3 cH2cH=cHcH2 cH2 _J_\ 0 /
-N
Me H Isopropyl H H cH3CH2CH=CHCH2CH2 - ------ -> /
)----Me H t-butyl H H 0-13 0-12cH-cHcH2 0-12--l----\--\
0\ /
\--ri .
-------_ __ _ Me H Vinyl H H CH3CH2CHHCH2CH2 -N

R R R EC R Ft R7 Compound Double bond configuration as per drawing Me H Allyl H H CH, CH2CHHCH2 CH2 ¨/¨ \--\

¨ o /
-N
- --t Me H CH2 H H CH, cH2cH--cHcH2 CH2 ----1-____ ON /
Cyclo- \_ propyl ?
_ Me H Butyl H H cif, cH20-1=-0icH2 0-12 - \
/
----N
_ _ -=
Me H Sec-butyl H H CH, CH2CHCHCH2 CH2 --/-\-\ 0 -----_ -- --H H CH3 H H CH, CH2CH=CHCH2 CH2 ---\--/-j N
-CH3 CH2CH=CHCH2 CH2 -_ H _ H CH3CH2CH2 H H cH, CH2CH=CHCH2 CH2 \--Orsi H H Isopropyl H H .
CH, CH2CH=CHCH2 CH2 R _\
- t----\_/--/-\----N
- r H H
- t¨butyl H H CH, CH2CH=CHCH2 CH2 o -\-7- -\----H H Vinyl H H
CH3 CH2CH=CHCH2 CH2 o ---\¨

?
¨ ¨
H H Al 1 yl H H CH3 CH2CH=CHCH2 CH2 o ---__ -CH3 c1-I2cHHCH2 CH2 o Cyclo- ----\-pr opy 1 R1 R2 R3 R R5 R6 R7 Compound Double bond configuration as per drawing H Butyl H H
_ _ CH3 CH2CH=CHCH2 CH2 o H
---\_/-1-\-N
_ H H Sec-butyl H
H CH3 CH2CH=CHCH2 CH2 _ \_0 ¨
_ CH2CH=CHCH2 CH2 /---\\___\ Q
N \
_ H H CH3CH2 H H- CH3 CH2CH=CHCH2 CH2 \ ¨ \
--N

-, I CH CH2CH=CHCH2 CH2 N
-H H Isopropyl H H
qµ
-NI
H H t-butyl H H
cH3 cii2cH=cHcH2 CH2 ___/ ¨\.__\ o, \¨ \
--N

. . .
H H Vinyl H
H CH3 CH2CH=CHCH2 CH2 . 0 ¨ \
-N
..
H H Al 1 yl H H
CH3 CH2CH=CHCH2 CH2 _J¨\ - 0 \¨\
--N
H H CH2 H _ H CH3 CH2CH=CHCH2 CH2 Cyclo- \--\
--N
pr opy 1 '?
H H Butyl H H CH3 CH2CH=CHCH2 CH2 _/¨_-\ 0 ___ \ ¨ \
-N

Fil R2 113 Ill Rs R6 R7 Compound Double bond configuration as per drawing -H H Sec-butyl H H
CH; CH2CH=CHCH2CH2 ____T----\___ 0 ¨ \
-------N
Our invention specifically relates to the novel compositions according to the formula I above:
R R R3 R4 R5 RE _________________ Compound Double bond configuration as per drawing _ .
H
,./,--...___/\ H Me (CH3)2C=CHCH2CH2 _ -. -, o H -- --H H Me (CH3)2C=CHCH2C-u 2 /
'L
li .
_______________________________________________________________________________ _____ _ H H Me (CH3)20=CHCH2CH2 o -, --. -- --- N
H
r-1,1 H H Me (0-13)2C-CHCH20-12 N
H
-_______________________________________________________________________________ _____ - _ H
H Me (CH3)2C=CHCH2CH2 I
----( -. 0 H
H H Me (cH3)2C-cHcH2CH2 "- 0 NN .--H
. -H H H cH, cH2cH=cticH2 CH2 NN ..' ...-H
--H H H CH3CH2CH=CHCH2CH2 H
. .
H cyclopropyl H H CHI CH2CH=CHCH2CH2 kA
_______________________________________________________________________________ ____ NI N
H

R1 R2 R3------i? R5 Rb Compound Double bond configuration as per drawing , , H cyclopropyl H H CH3 CH2CH=CHCH2CH2 H

H cyclopropyl H ___ H ________________ H cyclopropyl H H
-"---CH

u)I,,c7 H _________________________ cyclopropyl Me H
111111 o Me H H H Me le o -N.
....L., el HN
_______________ -____________________________________________________________________ H H H H Me el o ,I.

_ .
_ H H H H Me \ N..-k H
.
_ H H H Me H
cH3 CH2cHHcH2 cH2 o H
_ .
_ _______________________________________________________________________________ ______ H H H Me H CH3 CH2CHHCH2CH2 o Isrk H
H H Me H H tvCH
o .,,,..,_ ) =-...
N.A.,.......

______ _ _____________________________________________________________________________ H H Me H H
Cr ______ _ ___________________________________________ H H H H H
'''''''CH o ii H H H H CH

\ NJL
H
o Me Me Me H H _________ OH
_____________________________________________________ 010 IIAT( R1 R2 R3 Ra R5 R6 ______________ Compound Double bond configuration as per drawing _...
.
Me Me Me H H CH 0 EIN)11 _ Me H Et H Me (CH3)2C=CHCH2CH2 o -. --, ,....L.--N
H
/
Me H Et H Me (CH3)2C=CHCH2CH2 \N)L.,/
H
_ Refering to Formula II above, the present invention relates to the novel compositions according to the formula II above:
R7 Re R9 RI Geranyl 2,3-double Compound Bond configuration Cyclopropyl Me Me E
o ______ NH7' H
_ _ _______________________________________________________________________________ _____ .
Cyclopropyl Me Me Z

N
H
Me Me Me Me E
0 ______ --i N).
H
.
.
Me Me Me Me Z
o N),I...-H
_______________________________________________________________________________ _______ _ Me Me E

,.' H
_______________________________________________________________________________ ______ __ Me Me Z

H
Me Me E
o N
H
___________________ _ __________________________________ ;. Me Me Z
o N,1----,õ
H

These compounds and uses thereof have been found beneficial in augmenting or imparting an olfactory effect taste enhancement or somatosensory effect to a foodstuff, chewing gum, medicinal product, toothpaste, alcoholic beverage, aqueous beverage, snack, sauce or soup particularly providing a (a) umami taste, (b) salt effects, (c) flavor enhancement, and (d) preferred overall flavor profile.
More specifically, examples of the organoleptic properties for the dienalkylamides of our invention are as follows:
Relating to Formula I
R1 R2 R3 R4 Rb R6 Compound _____________ Taste profile _ _____________________________________________________________ H cyclopropyl H H cH3cH2cH=cHai2 o Moderate Umami, cH2 1,4)LT7 off fish oily H character - ________________________________________________________________ H cyclopropyl H H cH3 ,N,.., o Oily, moderate (cH2)4cH=cHcH2 cH2 -..-_,..-WIV
.),v umami H
-Me H , _______________________________________ .
H H H CH3CH2CHHCH2 \
o Potent warming at cH2 lOppm H
Relating to Formula II
R7 R8 RY R1 Compound Taste profile _ Cyclopropyl Me Me o Salt, MSG, Umami, ,N)LT7 mouthfeel, lasting H sweetness.
Cyclopropyl Me Me Salty, MSG, Umami, brothy, mouthfeel, sweetness.
N.J'y H
_ R7 118 R9 RI Compound Taste profile _______________________________________________________________________________ _______ ¨
Me Me Me Me 0 Some salt enhancement, =-. \ NA" umami and strong MSG
H effect, sweet end profile Me Me Me Me ' Salt enhancement, MSG ¨
enhancement, Umami, brothy, sweet end N profile H
_______________________________________________________________________________ _______ -Me 'Me 0 Moderate umami, salt ,' like, lemon character.
H
Me Me Moderate umami, some " saltiness.
H
_ _______________________________________________________________________________ ______ Me Me =-. 0 Clean, weak umami effect at lOppm H
_______________________________________________________________________________ _____ .
;'- Me Me -.. o \ N.J Clean, weak umami effect at lOppm H
Relating to Structure 3 -2 3 R4 Rb Re R7 R R Compound _____________ Taste profile H Cyclopropyl Et H Me (CA-13)2C=CH o Weak salt and CH2CH2 N, .,)1')V
Umami _______________________________________________________________________________ _______ _ Other novel compounds of the present invention include the following according to Structure 1 above:
R1 R2 R3 R4 R5 R6 Compound Double bond configuration as per drawing ________________________________________________________________________ _ H cyclopropyl H H OH3(CH2)4CH=CHCH2 CH2 /"\./\, o o H cyclopropyl H Me R1 R2 R3 R4 R5 R6 Compound Double bond configuration as per drawing H cyclopropyl H Me CH
J-y H cyclopropyl H Me Me 0 H cyclopropyl H Me CH
H cyclopropyl H Me H cyclopropyl H H CH
H
cyclopropyl H H ./CH
=0 H H Me CH
H H H Me N
H H - H H Me - H H Me CH
/CH
H H H
H H H CH

R1 R2 R3 R4 R5 R6 Compound Double bond configuration as per drawing Me /7., H Me (0-13)2C=CH o _ CH20-12 õ--k.--,-----------Other compounds of the present invention include the following according to Structure 2 above:
R1 R2 R3 R4 R5 R6 Compound H cyclopropyl H Me (CH3)2C=CHCH2CH2 o _ .-L,c7N) H
-_ H cyclopropyl H H
CH3CH2CH=CHCH2CH2 -.

H
H
47''' H Me (CH3)2C=CFICH2CH2 o N
H
_ H 1-3 H H Me -(CH3)20----CHCH2CH2 o ,,r1-z,..-,...,J,--., N
H
H H Me H Me (0-1020----CHCH2CH2 o _ N
_ H -Me Me H Me (0-13)2C=CHCH20-12 o N
H
_ Other compounds of the present invention include the following according to Structure 4 above:

, r------R1 R2 R3 R4 R5 R6 R7 __________________ Compound Double bond configuration _ as per drawing _ __ H cyclopropyl CH3 H __ H
______________________________________ CH3 CH2CH=CHCH2 CH2 _ ._ __ H cyclopropyl CH2CH3 __________________________________ H H CH3 CH2CHHCH2 CH2 _ H cyclopropyl CH2CH2CH3 H H cH3 CH2CH=CHCH2 CH2 --\=i-A-N
H cyclopropyl Isopropyl H H CH3 H cyclopropyl t-butyl H H cH, cH2cHticH2 cH2 _ .--\\--H cyclopropyl Vinyl H H CH3 CH2CHHCH2 CH2_ __v_i_A-131,1t1 ¨
H cyclopropyl Allyl ___________________________________ H H CH3 CH2CH=CHCH2 CH2 _ ----\ (--f\---H
_ H cyclopropyl CH2 H H CH3 CH2CH=CHCH2 CH2 ______________________ _ Cyclo------ --A \---N
propyl ,2..
H cyclopropyl butyl H H CH3 CH2CH=CHCH2 CH2¨
0,_<1 ---\_ ¨A--N
_ H cyclopropyl Sec-butyl H H CH3 CH2CHHCH2 CH2 -----i _ ----H cyclopropyl CH3 H H CHI CH2CHHCH2 CH2 _ N
\--ILI7 H cyclopropyl CH3CH2 H H CH3 Isr-.1 _ H cyclopropyl CH3CH2CH2 _______________________________ H H CH3 CH2CH=CHCH2 CH2 ___ N )4 H cyclopropyl Isopropyl H H CH3 CH2CH=CHCH2 CH2 r)C1...
¨
_______________________________________________________________________________ ______ _ _--,, R Rb 3 R4 Rb R.õ' Er R7 Compound ' Double bond configuration as per drawing H cyclopropyl t-butyl H , .
H CH3CH2CH=CHCH2CH2 _ r4,.....)*
H cyclopropyl vinyl H H CH3CH2CH=CHCH2CH2 __ H cyclopropyl allyl H H CH3CH2CH=CHCH2CH2 N)Y\\\ ¨
_ H cyclopropyl 0H2 H H CH3CH2CHHCH2CH2 Cyclo-propyl .,_ H cyclopropyl butyl H H CH3CH2CH=CHCH2CH2 H
cyclopropyl Sec-butyl H H CH3CH2CHHCH2CH2 _ N)Y
.-).
H cyclopropyl CH3 H - H
, 0 ' N\icr _ H cyclopropyl CH3CH2 H H ,CH
410 tsCI:T7 H cyclopropyl CH3CH2CH2 H H
./---CH 410 * tql!LC7 H cyclopropyl Isopropyl H H o OH
_ H cyclopropyl t-butyl H
o H
' OH
0 N)Y
/-\
_ H cyclopropyl vinyl H H ./."-CH o _ -:./. 0 .
N)L.,__y ______ H cyclopropyl allyl H H ' ./CH o _ R R R R' R W R7 Compound Double bond configuration as per drawing _ H cyclopropyl 0H2 H
H o _ '''''''CH
Cyclo-LI7' propyl - __________________________________________________________ H cyclopropyl butyl H H
''k=../ 410 x___ _iNV
_ H cyclopropyl Sec-butyl H Ho ='-'''CH
H ______________________________ cyclopropyl CH3 ______________________________________ H H. _ CH
el o H cyclopropyl CH3CH2 - H H ' /'-CH
le ____________ ___ = Na7 H cyclopropyl CH3CH2CH2 H - H /"CH
1.1 V
= N)7 r--1 , H __________________________________________________________ cyclopropyl Isopropyl H H
lei o 1110. N'jlii )\
H cyclopropyl - t-butyl H H '-CH

/ o ---1\
__ _ .
H cyclopropyl vinyl H H
-"'''CH

-,,-- 0 0" IseL'7 __ _ ______________________________________________________ H cyclopropyl ally1 H - H -.-'''CH

0111' N'IL-17 c=

R' R2 R3 R4 R5 Re R7 Compound Double bond configuration ,as per drawing H cyclopropyl CH2 H H
Cyclo- 110 propyl 11110. N)Ii/
-..<j H cyclopropyl butyl H H r/CH

o II N)LT7 H cyclopropyl Sec-butyl H ' H CH
.,- o N)11 .......õ,) r _ 411 H cyclopropyl CH3 Me H
¨ 1 o 0 4 N)*
H cyclopropyl CH3CH2 Me H
lel 410 ts4)3Y

H cyclopropyl CH3CH2CH2 -Me H
4110 00 1 Njj:V

H cyclopropyl Isopropyl Me H

4 o ',2'v 'H cyclopropyl It-butyl Me H

_ H cyclopropyl vinyl Me H

4 o _ - _ H cyclopropyl allyl Me H

o 40 4 N-k7 -..,-_-H cyclopropyl CH2 Me H o Cyclo-0110 I. 4 N-k7 propyl .
_ R R R R' R EC R7 Compound Double bond configuration as per drawing H ______________________________ cyclopropyl butyl Me H
el 0 0 4 N)Y
._ H cyclopropyl Sec-butyl 'Me H
el o -----c'i -H ___________________________________ cyclopropyl CH3 Me H
lel IP
o _ 1. 1,11-H ___________________________________ cyclopropyl CH3CH2 Me H
110 lb o 0. 1,4-,) H cyclopropyl CH3CH2CH2 Me H
o 1.1-kv r) H ___________________________________ cyclopropyl - Isopropyl 'Me H
lel IP
o 0,, NA,77 )-.
_ H cyclopropyl t-butyl Me H

010 o 0. NJCv >l' H ___________________________________ cyclopropyl __________ Vinyl Me H _ 410 o v e) ' H cyclopropyl Ally' Me 'H ________________ 110 o 0. NA-7 Rl R2 R3 R4 R,b R,E, R7 ____________ Compound Double bond configuration as per drawing H cyclopropyl CH2 Me H
Cyclo-__________________________________________________________ _111 410 o Propyl 1,(kv H ___________________________________ cyclopropyl Butyl Me H
1111 110 o ) H __________________ cyclopropyl ______________________________________________________ Sec-butyl -Me -H
411 110 o 0. NJL-7 H cyclopropyl CH3 H Me ________________________________________________ r? Y
H _______________________________ cyclopropyl CH3CH2 _______ H Me o ______ H
_______________________________________________________________________________ ______ cyclopropyl CH3CH2CH2 -H Me NO
o N1),7 H
_______________________________________________________________________________ ______ cyclopropyl isopropyl -H Me-lel o -_______________________________________________________________________________ _____ H cyclopropyl t-butyl H Me -o _ _______________________________________________________________________________ ______ H ______________________________ cyclopropyl vinyl ________ -H -Me o NL..)_....
__ 410 -H __ -cyclopropyl allyl H Me _ o --H cyclopropyl CH2 H Me o _ Cyclo-010 0 . N-jH7 propyl -<]

R R R 12 R R" R7 Compound Double bond configuration as per drawing H _____________________________________ cyclopropyl butyl __ H Me 40 le, . tklri H _____________________________________ cyclopropyl Sec-butyl H Me lel i _____________ o H _____________________________________ cyclopropyl CH3 _____________________________ H Me NO 110 o _ = 7)*
_ H 'cyclopropyl CH3CH2 H Me 1111 410 o = N)Y
*
H _____________________________________ cyclopropyl CH3CH2CH2 H Me 1111 110 o __ 1,1"1Y
H _____________________________________ cyclopropyl isopropyl H Me ___________________ 110 410 o = N)Y/k H cyclopropyl t-butyl H Me -1>='''N )C7 H _____________________________________ cyclopropyl vinyl __ H Me 1110 110 o ___________ __ N)Ls.,Lr H _____________________________________ 'cyclopropyl ally' __ -H Me 1111 010 o ___________ __ = N)t'T7 --H cyclopropyl CH2 H 'Me _ Cyclo-110 010 o Propyl = N)Y

R R R 1:2' R W R7 Compound Double bond configuration as per drawing , .
H cyclopropyl butyl H Me lil 40 0 1. rN)tv I r-, H cyclopropyl Sec-butyl H Me lei 40 0 H cyclopropyl CJ-13 Me H CH3CH2CH=CHCH2CH2 oA __ _ ---\ -/-----tili N
- , H cyclopropyl CH3CH2 Me H
CH3CH2CH=CHCH2CH2 _ _ ) H cyclopropyl CH3CH2CH2 Me H
cH3CH2CH=CHCH2CH2 NI N
_ H cyclopropyl isopropyl Me H
cH3CH2CH=CHCH2CH2 o__I
_---\_=/----A---H cyclopropyl t-butyl Me H
cH3CH2CH=CHCH2CH2 ' o 7,1 - \ T-P(----N N
---.) H cyclopropyl vinyl Me H cH3 cx2cxxcH2 LI \I
_ __________________________________________________________ H cyclopropyl allyl Me H cH3CH2CHHCH2CH2 N
H cyclopropyl CH2 Me - H cH3 cH2cH.---cHcH2 CH2.
OH
Cyclo-propyl .\) _ __________________________________________________________ H cyclopropyl butyl Me H CH3CH2CHHCH2CH2 _ (D__A
H cyclopropyl Sec-butyl Me H
CH3CH2CHHCH2CH2 _ o__,1 ----\____/"AV\-N

R1 R2 R3 R4 R5 R6 R7 __________________ Compound Double bond configuration as per drawing H cyclopropyl CH3 Me H CH3 CH2CH=CHCH2CH2 - 0 \.õ,xinf,K17 H cyclopropyl CH3CH2 Me H CH3 CH2CH=CHCH2 CH2 0 \-----1----)-Kr H cyclopropyl CH3CH2CH2 Me H CH3 CH2CHHCH2 CH2_ H cyclopropyl isopropyl Me H CH3 CH2CH=CHCH2 CH2 .
o H cyclopropyl t-butyl Me H
CH3 CH2CH=CHCH2 CH2 0 _ H cyclopropyl vinyl Me H CH3 CH2CH=CHCH2CH2 0 - _ H cyclopropyl allyl Me H
CH3 CH2CHHCH2 CH2 _ 1--...--_ -H cyclopropyl CH2 Me H CH3 CH2CH=CHCH2 CH2 _ o Cyclo-propyl _ H cyclopropyl butyl Me H CH3 CH2CHHCH2 CH2 _ H cyclopropyl - Sec-butyl Me H cH3cH2ciirici-12oi2 _ o .."-.
_ . .
H cyclopropyl CH3 H H
411 ei 11 jy _ H cyclopropyl CH3CH2 H H
I. o R R R R' R Pi' R7 Compound Double bond configuration as per drawing -H cyclopropyl CH3CH2CH2 H H
lel 4 ') o H ____________________________________ cyclopropyl isopropyl H H

)o r I. ;c4i H cyclopropyl t-butyl - H H ' I.

H ________________________________ cyclopropyl vinyl - H H

o 40 . jYr .
H cyclopropyl allyl H H

07.>2) o H cyclopropyl CH2 _______________________ H H ____ o Cyclo-1111 Op 0. N)V
propyl . H cyclopropyl butyl H __ H
0 ___________________________________________________________________________ . . N
___ _____________________________________ 411 H ____________________________________ cyclopropyl Sec-butyl H H ____________ ___ o _ H cyclopropyl CH3 H H

1X---y1I7 H ____________________________________ cyclopropyl CH3CH2 __ H ' H
________________ _ lel 110 o ___ = N)Y
H ____________________________________ cyclopropyl CH3CH2CH2 H H
1111 110 o = N

RI R2 R3 R4 R5 R6 R7 Compound Double bond configuration ,as per drawing H __________________________________ cyclopropyl isopropyl H H
= (10 0 = NAV
H __________________________________ cyclopropyl t-butyl H H

= N)Y
H ______________________________ cyclopropyl vinyl H H

H cyclopropyl allyl H H
410 1;, H cyclopropyl CH2 Fl H
Cyclo-propyl 1,1)Y
H cyclopropyl butyl H H

H cyclopropyl Sec-butyl -1-1 H

NI)Lr7 Me Me CH3 H Me (CF13)2C----CHCH2CH2 Me Me CH3CH2 H Me (CH3)2C----- -Me Me CH3CH2CH2 H Me (CH3)2C--NAT( R R R R" R EU R7 Compound Double bond configuration as per drawing Me Me isopropyl H Me (CH3)2C=CHCH2CH2 1<c) )\
Me Me t -butyl H - Me (CH3)2C=CHCH2CH2 o -.
Me Me vinyl - H Me (CH3)2C=CHCH2CH2 o isr-It Me Me allyl H Me (CH3)2C=CHCH2CH2 o _____ _ _.....3)'' Me Me CH2 H Me (CH3)2C=CHCH2CH2 o _____ .
Cyclo-p ropy 1 µ17.j Me Me butyl H
Me (CH3)2C=CHCH2CH20 _ Me Me Sec-butyl H Me (CH3)2C=CHCH2CH2 __ 0 _ \) Me Me CH3 H Me (CH3)2C:CHCH2CH2 I
Me Me CH3CH2 H Me (CH3)2C:CHCH2CH2 Me Me CH 3 CH 2 CH2 H Me (CH3)2C:CHCH2CH2 z_iril<
Me - Me isopropyl H Me - (CH3)2C:CHCH2CH2 N.A.-.<
.,' Me Me - t -but yl H Me (CH3)2C:CHCH2CH2 rf)<
--7t RI R2 R3 R4 Rb R6 R7 ________________ Compound Double bond configuration as per drawing _ Me Me vinyl H Me (CH3)2C:CHCH2CH2 o _ Me Me allyl H Me (CH3)2C:CHCH2CH2 1N'j<
-Me Me 0H2 H Me (CH3)2C:CHCH2CH2 Cyclo- o propyl N)L
Me Me butyl H Me ' (CH3)2C:CHCH2CH2 Me Me Sec-butyl H Me (CH3)2C:CHCH2CH2 o _ Me (CH3)2C=CHCH2CH2 o .

Me (CH3)2C=CHCH2CH2 o Me (CH3)2C=CHCH2CH2 o \
N) ) H H
isopropyl H Me (CH3)2C=CHCH2CH2 o .
H H t -but yl H
Me (CH3)2C=CHCH2CH2 o NI) '.\
H H vinyl H Me (CH3)2C=CHCH2CH2 o _ NL...
H H allyl H
Me (CH3)2C=CHCH2CH2 o N)N--' Me (CH3)2C=CHCH2CH2 o Cyclo-propyl RI R2 R3 R4 R5 R6 R7 Compound Double bond configuration as per drawing butyl H Me (CH3)2C=CHCH2CH2 N) Sec-butyl H Me (CH3)2C=CHCH2CH2 N
CH3 H Me (CH3)2C=CHCH2CH2 CH3CH2 H Me (CH3)2C=CHCH2CH2 CH 3 CH2 CH 2 - H Me (CH3)2C=CHCH2CH2 isopropylH Me (CH3)2C=CHCH2CH2 N
t -butyl H Me - (CH3)2C=CHCH2CH2 1 o !s1) vinyl H Me (CH3)2C=CHCH2CH2 a 1 lyl H Me (CH3)2C=CHCH2CH2 0H2 H Me (CH3)2C=CHCH2CH2 Cyclo-propyl butyl H Me (CH3)2C=CHCH2CH2 R1 R2 R3 R4 Rs R6 R7 Compound Double bond configuration as per drawing _ H H Sec-butyl H Me (CH3)2C=CHCH2CH2 o N)tN
Me H CH3 Me H
laill 0 Me H CH3CH2 Me H

40 ) 0 ts1) Me H CH3CH2CH2 Me H

0 ______ Me H isopropyl Me H

= 4 N) )\
. ¨
Me H t-butyl Me H

el 4 N) ----I Me H vinyl Me H

0 _______ 4 )-T, Me H - allyl Me H

o el 4 N) _ Me H CH2 Me H
o Cyclo- 11 gall 4 N
propyl Me H butyl Me H

o 40 4 N1) \---\----.
¨
Me H sec-butyl Me H
le o _______ 40 4 N) Me H CH3 Me H
lei 40 .

R1 R2 R3 R4 Rb RE R7 ______________ Compound Double bond configuration ,as per drawing , _______________________________________________________________________________ _____ .
Me H CH3CH2 Me H
el 010 o = N'IL
Me H CH3CH2CH2 Me ____________ H
ill 11110. N )I
--..-\
, Me H isopropyl Me H

o = INI) _ Me H t-butyl Me H

410 o = N) A
Me H vinyl Me __ H
lel 410 o Me H allyl Me __ H

010 o = N).
. _ ________________________ Me H CH2 Me H
Cyclo- 1 11111 IP o propyl N)-Me H butyl Me H

III. N
Me H Sec-butyl Me H _______ 1110 110 o ____________ ____ K_-R1 R2 R3 R4 Rs R6 R7 Compound Double bond configuration as per drawing Me H CH3 H Me el el o Me H CH3CH2 H Me o ei N) C ________ Me H CH3CH2CH2 H Me o Me H isopropyl H Me 1111 o _ Me H t-butyl H Me o Me H vinyl H Me , .
Me H ally' H Me o K,--Me H CH2 H Me o Cyclo-1,,,\I,ria._ propyl _ Me H butyl H Me Me H Sec-butyl H Me o NIK
_ Me H CH3 H Me 110 o r;1 Me H CH3CH2 H Me 410 o ) Ill R2 R3 R4 115 R6 R7 _________________ Compound Double bond configuration as per drawing Me H CH3CH2CH2 H Me ________________________________ 1111 110 o = N \) N
Me H Isopropyl H Me 110 010 o = ts!) /\
Me H t-butyl H Me -----", Me H Vinyl H Me ...;i.\

o L=
Me H Allyl H Me 1111 410 o = N)-7.
Me H CH2 H Me Cyclo-NO I
o Propyl .----/
Me H Butyl H Me ____________________________________ o \ \
Me H Sec-butyl H Me 10 110 o H H ______ CH3 __ Me H
411 o ______ el 4 r4) I
H H CH3CH2 Me H
00 0 4 N ____________ R R2 R3 R4 R7 _____________ Compound Double bond configuration as per drawing .
H _________________________________ H __ CH3CH2CH2 'Me H
110 o ______ . 1 N) K ____ .
H H Isopropyl Me H
'''j o =--, ..-4\
H _________________________________ H __ t-butyl Me H
NO o ______ Olt 1 w'jL' ....)- _ _ 'H H Vinyl Me H
1111 o ______ el 1 N) L.
Me H _ _______________________________________________________________________________ _ H H Allyl 1110 o 00 1 Nj'' Me H o Cyclo-NO
Propyl Olt 44,2)L' III _ H H _______ Butyl _________________________________ Me H __ o lit 1 N)L' ..õ...\___ H _________________________________ H __ Sec-butyl Me H
110 o _____ 010 1 N-j-/)\
H H _________ CH3 __ Me H
40 010 o lo, ri)., i H _________________________________ H __ ' CH3CH2 Me H
411 110 o = N\ )L
/
H _________________________________ H __ CH3CH2CH2 Me H
NO 410 o = N)L' H _________________________________ H __ Isopropyl Me H
41 110 o = T) A

R R R R' R IC R7 Compound Double bond configuration as per drawing _ _ H ' H t-butyl Me H
410 lip 0 N)L-4, _ H H Vinyl Me H
lel 410 0 J1, 1õ..., H H ________ Allyl __ Me H
OP o _ _________________________________________________________ H H CH2 Me H
Cyclo-1111 410 1, Propyl , .
.
H H Butyl Me H

_______________________________________________________________________________ ______ -H H I Sec-butyl Me H

H H CH3 H Me ill 1 .1., - - ___________________________________________ o H - H CH3CH2 H Me ill 401 N) -k H _____________________________________ H __________________ CH3CH2CH2 H Me 1, .
rsIL
o I H H Isopropyl H Me _________________ 110 lit I .
,i,e2' o H H t-butyl H Me _______ 2.)!,--R' R2 R? RL4 Rõb R.6 R7 ________________ Compound Double bond configuration as per drawing , _______________________________________________________________________________ ______ H H ' Vinyl H Me o 40:1 t___ __ H H Allyl H Me el 40 . NK
,,.._._._ H H
CH2 H Me o Cyclo-Propyl H _____________________________________ H
_____________________________________________ Butyl H Me lei III ' wl' L, _ _ _________________________ H H Sec-butyl H Me II
o . .
H H CH _ 3 H Me lel lb o rr-l' i _ _______________________________________________________________________________ ______ H H CH3CH2 H Me gill 410 o .
00.

H - H __________________ CH3CH2CH2 H Me ___________ .
lel IP o _______________________________________________________________________________ _______ _ _ _____________________________ H _____________________________________ H __________________ Isopropyl H Me 110 o ts11) ÷
H ' H ' t -butyl __ -1-1 ______________________________________ Me 410 o 10.
N'Il /.
H _____________________________________ H
_____________________________________________ Vinyl H Me 110 o =

Ill R2 R3 R4 le R6 R7 Compound Double bond configuration as per drawing _ H H Ally' H Me 140 SI o N
H H CH2 H Me Cyclo-el I
o Propyl NJL

-H H Butyl H Me o N-11"--"."-\---.
H H Sec-butyl H Me ,,.= o N
------H H CH3 Me H cH3 cii2cH=cHCH2 CH2 A>___ _.
, Me H cii3 cH2cH=Dicii2 cH2 o 2_, \
_ H H CH3CH2CH2 Me H
CH3CH2CH=CHCH2CH2 \
¨\ 7--A(.--N/¨\
\----H H Isopropyl Me H
CH, CH2CH=CHCH2CH2 - o -_ _ .
H H t -butyl Me H CH3CH2CH=CHCH2CH2 \
__\ 7._/LX__,Ni H H Vinyl Me H CH3 CH2CH=CHCH2CH2 _\ AQ___ L.. _ H H Ally' Me H
CH 3 CH2CH=CHCH2CH2 o --\=7--A--N
. .
H H CH2 Me H CH3CH2CH=CHCH2CH2o %
/
Cyclo-X__N
Propyl '77 =
R1 R2 R3 R4 R5 R6 R7 Compound Double bond configuration as per drawing , .
H H Butyl Me H CH3 CH2CHHCH2 CH2 N
¨
\
H H Sec-butyl Me H
cH3 cH2cHHcH2 cH2 o \\
i --\=j----A¨N
\----( .
H H CH3 Me H CH3CH2CHHCH2CH2 H H CH3CH2 Me H

\''''.===''.Vr''N-jt''' . H H CH3CH2 CH2 Me H

\----\
i.
H H Isopropyl Me H CH3 CH2CH=CHCH2 /I
H H t--butyl Me H CH3 CH2CH=CHCH2 CH2 /j\----H H Vinyl Me H CH3 CH2CHHCH2 CH2 '''L-/-N,X1,--- W
-_ H H Al 1 yl Me H CH3 CH2CH=CHCH2 CH2 hN:"IL
-H H CH2 Me H cH3 cH2cH-cHCH2 CH2 o Cyclo-Pr opyl ' H H Butyl Me H CH3CH2CH=CHCH2 Cl-I2 o \---\
H
-\ H Sec-butyl Me H cH3 cH2CH---cHCH2 CH2 -.--Ill Rl R2 R3 R4 R5 R6 R7 __________________ Compound Double bond configuration drawing H
per rawing _ ../-.
_ o _ H H Isopropyl H H
..)\
_HH t-butyl H ' H __________________________________________ , - - o '''''CH
_ .
H H ' Vinyl H -H
''''''''CH o _ _______________________________________________________________________________ ______ H H ' Al lyl H - H - /-CH o ,..,.
õ
.
_______________________________________________________________________________ ______ _ Cyclo- 410 N)1' ) Propyl H - h Butyl H 'H
-----CH o _,-14,, H H Sec-butyl H H CH 0 ,..,õ e , N).-----) I
_ H H CH3 H H - ..,."-CH

OP
r;1.)-I
_______________________________________________________________________________ ______ .
H H CH3CH2 H H --."-CH

=.,. o i _______________________________________________________________________________ _______ _ $
- o _______________________________________________________________________________ _______ _ RI PL2 F0 R4 R5 Rb R7 __________________ Compound Double bond configuration as per drawing H ' H Isopropyl H H "CH

o = N)-=
/1\
_ H H t-butyl H H 'CH

= N) /i-H ' H Vinyl H H r'CH

. ).-H H Allyl H H -'''''CH

:-...---L
= Ni........c.õ
_ _ Cyclo- 410 -,,- o Propyl = Nj H H Butyl H H -."'"CH

-,.,--- 0 \
_ H ' H Sec-butyl H H ..,"-.CH

,,,-- .
= N) ''''''CH o '-,-) le T

''.'CH o _ ''CH o R1 R7- R3 R4 Rb Rb R7 Compound Double bond configuration as per drawing o H H Isopropyl H H
o H H t-butyl H H
H H Vinyl H H
7''''CH o H H Allyl H H
v'''CH o 0. N
, Cyclo-.-...) Propyl Cr H H Butyl H H
'''CH 9 ../"' 410 . N'''):
o H H Sec-butyl H H
\

o OP.
N
i . _ ,---CH

õ

--CH

.1./
o II
Nrjt ---'\
_ H H Isopropyl H H
'CH

`.../ o tsrjt A

I

Fe- R2 R3 Ra R5 Rb R7 __________________ Compound Double bond configuration as per drawing _ H H t-butyl H H

../ o ,T\
, .
H H Vinyl H H /--CH

Ni....... ..,_ _ H H Allyl H H
.
.

cyclo- 110 ',) o propyl tslt,t H H Butyl H H

H H Sec-butyl H H 7'''''CH
IP
. wl-_., Me Me 0H3 H H 'CH
r111.<
Me Me CH3CH2 H H CH o C _ Me Me CH3CH2CH2 H H
_ .
Me Me Isopropyl H H
¨ , , Me Me t-butyl H H
_ _______________________________________________________________________________ ______ 121 R2 R3 R4 Rb Rb R7 Compound Double bond configuration as per drawing Me Me Vinyl H H '''CH o __ ____ _____________________________________________________________________________ __ Me Me Allyl - H H 'CH o N)L-.,) _ Me Me 0H2 H H ''CH o Cyclo- 410 N)LK

Propyl __ ___ ____________________________________________________ Me Me Butyl H H r/-CH o õ
Me Me Sec-butyl H H 'CH
,-,-- 0 ')H<
Me Me CH3 H H -CH ___ Mih 1 qiP o wiLx( I
, Me Me CH3CH2 H H -'CH 010 41;11 __ ,( .,-_ .
________________________ Me Me CH3CH2CH2 H H .CH
010 1 o N)(x( ., , _______________________________________________________________________________ ______ Me Me Isopropyl H H ' (CH o Xl* ' Me Me . t-butyl ' H H .7--CH 1 0 )*o N
Me Me Vinyl H H
./. ,.....
_...j!q<
Me Me Allyl H H -..'CH
0 44 o ,,,...fil-I<

-Rl R2 R3 R4 _________ R5 R6 R7 Compound Double bond configuration as per drawing Me Me CH2 H H /'--CH ga 1 _ Cyclo-'F N5X
Propyl V) Me Me Butyl H H
_ --7CH i N-1---.<
_/--/
Me Me Sec-butyl - H - H ICH 1 ==.- o µP

Y ,i)..<
Me H CH3 H Me (CH3)2C=CHCH2CH2 o I
\ N)C
I
) Me H CH3CH2 H -Me (CH3)2C=CHCH2CH2 o =
I /
__ ¨ ______________________________________________________ Me H CH3 CH2 CH2 H r Me (CH3)2C=CHCH2CH2 o _ H
Me H Isopropyl H Me (CH3)2C=CHCH2CH2 o Me ' H t -but yl H Me (CH3)2C=CHCH2CH2 o >1 Me H Vinyl H - Me (CH3)2C=CHCH2CH2 o ./
-Me ' H Allyl H Me (CH3)2C=CHCH2CH2 o --.
11) Me H CH2 H Me (CH3)2C=CF1CH2CH2 o __________ .
Cyclo-N)L/
Propyl '') Me H Butyl H Me (CH3)2C=CHCH2CH2 o ) /
) _ R1 R2 R3 R4 R5 R6 R7 __________________ Compound Double bond configuration as per drawing _ Me H Sec-butyl H Me -(CH3)2C=CHCH2CH2 0 y /
- .
- Me H CH3 H Me (CH3)2C=CHCH2CH2 Pi)( _ , - Me H CH3CH2 H Me (CH3)2C=CHCH2CH2 -L,=.,.,.--j,<L o NK--C
- Me H CH 3 CH2 CH2 H Me (CH3)2C=CHCH2CH2 5NA-( _ Me H Isopropyl H Me (CH3)2C-CHCH2CH2 N-k--Me H t -butyl H Me (CH3)2C=CHCH2CH2 N
;\
Me H Vinyl H Me - (CH3)2C=CHCH2CH2 _ - Me H Al 1 yl H Me (CH3)2C=CHCH2CH2 SIL"( -Me H CH2 H Me ' (CH3)20-CHCH2CH2 Cyclo- o propyl Me H butyl H Me (CH3)2C=CHCH2CH2 R R R P. R R. R7 Compound Double bond configuration as per drawing Me H . Sec-butyl H Me - (CH3)2C=CHCH2CH2 _ IL-C
Me H CH3 H Me (CH3)2C=CHCH2CH2 o I
.._ ¨
Me H CH3CH2 H Me (CH3)2C=CHCH2CH2 o _ -Me H CH3CH2CH2 H Me (CH3)2C=CHC1-12CH2 o ))H7 Me H Isopropyl H Me (CH3)2C=CHCH2CH2 I 0 _ Me H t-butyl H Me (CH3)2C=CHCH2CH2 o >n)11Y' _ Me H Vinyl H Me (CH3)2C=CHCH2CH2 o ...'"------'----->N--11"-/7 --, I
Me H Allyl H Me (CH3)2C=CHCH2CH2 o N)Y
Ili Me H CH2 H Me (CH3)2C=CHCH2CH2 o Cyclo-Propyl V) _ _ Me H Butyl H Me (CH3)2C=CHCH2CH2 "-(LsV
) /
. _ Me H Sec-butyl H Me (CH3)2C=CHCH2CH2 o --------'''''.----->-"N'Il'--V
Y
Me H CH3 H Me (CH3)2C=CHCH2CH2 ..L.1,<

_ Me H CH3CH2 H Me (CH3)2C=CHCH2CH2 o (kr/

- RI R2 R3 RK5 R6 R7 _____________________ Compound Double bond configuration as per drawing Me H CH 3 CH 2 CH2 H Me (CH3)2C=CHCH2CH2 5NAV _ Me H Isopropyl H Me (CH3)2C=CHCH2CH2 -, L, joy, ,As1 Me H t -but y 1 H Me (CH3)2C=CHCH2CH2 I,< o Nj-LV ___ Me H Vinyl H Me (CH3)2C=CHCH2CH2 I
o j1--it--7 Me H Allyl H Me (CH3)2C=CHCH2CH2 j1L-7 , _ Me H CH2 H Me (CH3)2C=CHCH2CH2 _ Cyclo-propyl Will/
Y
Me H butyl H Me (CH3)2C=CHCH2CH2 4 o Y*
Me H - Sec-butyl H Me (CH3)2C=CHCH2CH2 N)Y
Me H CH3 H Me (CH3)2C=CHCH2CH2 o I
Me H ' CH 3 CH2 H - Me (CH3)2C=CHCH2CH2 o _ rNA----Me H ' CH 3 CH2 CH2 H Me (CH3)2C=CHCH2CH2 1 o _ N
) _ R' R2 R3 R4 Rs R6 R7 _______________ Compound Double bond configuration as per drawing Me H Isopropyl H Me (CH3)2C=CHCH2CH2 o NK--1--, Me H t -butyl H Me (CH3)2C=CHCH2CH2 o _______ _ \
INI) Me H Vinyl H Me (CH3)2C=CHCH2CH2 o /) Me H Allyl H Me (CH3)2C=CHCH2CH2 o rl ) I
Me H CH2 H Me ' (CH3)2C=CHCH2CH2 o Cyclo-Propyl Me H Butyl H Me (CH3)2C=CHCH2CH2 o Nr-1 ) ) Me H Sec-butyl H Me (CH3)2C=CHCH2CH2 o _ \ NK------) Me H CH3 H - Me (CH3)2C=CHCH2CH2 i Me ________ - H CH3CH2 H Me (CH3)2C=CHCH2CH2 o -_______________________________________________________________________________ ______ Me H ' CH3CH2 CH2 - H Me (CH3)2C=CHCH2CH2 Me H Isopropyl H Me ' (0-13)2C=CHCH2CH2 NK
Me H t -butyl H Me (CH3)2C=CHCH2CH2 o /-R1 R2 R3 R4 Rs R6 R7 _______________ Compound Double bond configuration as per drawing Me H Vinyl H Me (CH3)2C=CHCH2CH2 -L'-').(L o -_,-----J
Me H Ally1 H Me (CH3)2C=CHCH2CH2 %), Me H CH2 H Me (CH3)2C=CHCH2CH2 .
Cyclo-,L.,-- o propyl N'k=-'1) Me H butyl H . Me (CH3)2C=CHCH2CH2 "nrY-L
.-) ..-Me H Sec-butyl H 'Me -(CH3)2C=CHCH2CH2 N)*
--.-\) Me H 0H3 H Me (CH3)2C=CHCH2CH2 o )1, N
I
- Me H CH 3 CH2 H Me -(CH3)2C=CHCH2CH2 o )-L.---.
I
Me H CH 3 CH2 CH2 H Me (CH3)2C=CHCH2CH2 o -..
) ' - Me H ]Isopropyl H Me ' (C113)2c=cHCH2CH2 o .k...---., N
-Me -H t -but yl - H Me (CH3)2C=CHCH2CH2 o -.
N
Me H Vinyl - H Me (CH3)2C=CHCH2CH2 on _ .%1 - Me H Allyl H Me - (CH3)2C=CHCH2CH2 o _ -.
e _ R R R3 R4 R5 R6 R7 __________________ Compound Double bond configuration as per drawing Me H CH2 H Me (CH3)2C=CHCH2CH2 Cyclo-Propyl Me H Butyl H Me (CH3)2C=CHCH2CH2 rs.4 Me H Sec-butyl H Me (CH3)2C=CHCH2CH2 Me H CH3 H Me (CH3)2C=CHCH2CH2 Me H CH 3 CH2 H Me (CH3)2C=CHCH2CH2 Me H CH 3 CH 2 CH2 H Me (CH3)2C=CHCH2CH2 Me H Isopropyl H - Me (C1-13)2C=CHCH2CH2 _ _______________________________________________________________________________ _____ Me H z -but yl H Me (CH3)2C=CHCH2CH2 Me H Vinyl H Me (CH3)2C=CHCH2CH2 Me H Allyl H Me (CH3)2C=CHCH2CH2 NJ=
Me H CH2 H - Me (CH3)2C=CHCH2CH2 Cyclo-propyl N.J=

R R R R' R EC R7 Compound Double bond configuration as per drawing Me H butyl H Me (CH3)2C=CHCH2CH2 ;
---Me H Sec-butyl H Me (CH3)2C=CHCH2CH2 _ Me H C1-i3 H Me ' (CH3)2C=CHCH2CH2 I
Me H CH3CH2 H - Me (C1-13)2C=CHCH2CH2 o _ I
_ Me H CH3 CH2 CH2 H Me (CH3)2C=CHCH2CH2 ) Me H Isopropyl H Me (C1-13)2C=CHCH2CH2 ioL,L,, -''''>='N
./.
- __________________________________________________________ Me H t -butyl H Me (CH3)2C=CHCH2CH2 o i _____ _ -, l-----I ___________________________________________________ Me H Vinyl H Me (CH3)2C=CHCH2CH2 _ ______________________________ /.J
__________________________________________________________ _ _______________________ Me H Al 1 yi ' H Me (CH3)2C=CHCH2CH2 o _ -, ----i - rj Me H CH2 H Me (CH3)2C=CHCH2CH2 o Cyclo-Propyl '7) Me H Butyl H Me (CH3)2C=CHCH2CH2 o 1 jj _ __________________________________________________________ Me H Sec-butyl H Me (CH3)2C=CHCH2CH2 o 1 ----) R1 R2 R3 R4 P. R6 R7 Compound Double bond configuration as per drawing Me H CH3 H Me (CH3)2C=cHCH2CH2 N
Me H CH3CH2 H Me 1 (CH3)2C=CHCH2CH2 o Me H CH3CH2CH2 H Me (CH3)2C=CHCH2CH2 o Me H Isopropyl H Me - (CH3)2C=CHCH2CH2 \
Me H t-butyl H Me (CH3)2C=CHCH2CH2 /
Me H Vinyl H Me (CH3)2C=cHCH2CH2 Me H Allyl H Me (CH3)2C=CHCH2CH2 _ Me H CH2 H Me (CH3)2C=CHCH2CH2 Cyclo- o propyl Me H butyl H Me (CH3)2C=CHCH2CH2 /I) Me H Sec-butyl H Me (CH3)2C=CHCH2CH2 o H cyclopropyl CH3 H H CH3(CH2)4CH=CHCH2 CH2 /

R1 R2 R3 R4 R5 R6 R7 __________________ Compound Double bond configuration , as per drawing H cyclopropyl CH3CH2 H H
CH3(CH2)4CH=CHCH2 CH2 H cyclopropyl CH 3 CH2 CH2 __________________________ H H CH3(CH2)4CH=CHCH2 cH2 (NjY
H cyclopropyl Isopropyl H H CH3(CH2)4CH=CHCH2 CH2 NI -L'V
/\
H cyclopropyl t-butyl H H
CH3(CH2)4CH=cHCH2 CH2 H cyclopropyl Vinyl =H H CH3(CH2)4CH=CHCH2 CH2 0 H cyclopropyl Allyl ____________________________________ H H CH2(CH2)4CH=CHCH2 CH2 )1)LT7 H cyclopropyl CH2 H H
CH3(CH2)4CH=CHCH2 CH2 Cyclo-Propyl NjLV
H cyclopropyl Butyl H H
CH3(CH2)4CH=CHCH2 CH2 RI. R2 R3 R4 Rb R R7 ___________________ Compound Double bond configuration ,as per drawing - -H cyclopropyl Sec-butyl H H CH3(CH2)4CH=CHCH2 CH2 H cyclopropyl CH3 H H CH3(CH2)4CH-CHCH2 CH2 Ni-kq H cyclopropyl CH3CH2 H H CH3(CH2)4CH=CHCH2 CH2 H cyclopropyl 1 CH 3CH 2CH 2 H H CH3(CH2)4CH=CHCH2 CH2 o H cyclopropyl Isopropyl - H H CH3(CH2)4CH=CHCH2 H cyclopropyl t-butyl H H
CH3(CH2)4CH=CHCH2 CH2 H cyclopropyl Vinyl H H
CH3(CH2)4CH=CHCH2 CH2 H cyclopropyl Allyl H H
CH3(CH2)4CH=CHCH2 CH2 rsf-/
no emu R. in R7 Compound Double bond configuration as per drawing H cyclopropyl CH2 H H CH3 (CH2)4CH-clICH2 CH2 Cyclo-Propyl 1 o rsi)/
H cyclopropyl Butyl H H
CH3(CH2)4CH=CHCH2 CH2 -.

/
H cyclopropyl Sec-butyl H H CH3(CH2)4CH=CHCH2 -.

hrl'q H cyclopropyl CH3 H MeCH -7--0 0.
v0 H cyclopropyl CH3CH2 H Me 0 1, yy 'CH
H cyclopropyl CH3CH2CH2 H
Me /CH 0 , )j)y H cyclopropyl I sopro;Dy 1 h Me -.CH 0 ---:...,-H cyclopropyl t-butyl H Me H cyclopropyl Vinyl H Me r'"CH o ________fjY

H cyclopropyl Ally' H MeCH
0 1, cy -'' ,---I
H cyclopropyl CH2 H Me "CH o Cyclo- 0 N)Y
,,,---=.,õ
Propyl -) .1 R R RR. R R R7 Compound Double bond configuration as per drawing H cyclopropyl Butyl H MeCH
N
,f) TY
H cyclopropyl Sec-butyl H Me CH
H cyclopropyl CH3 H -Me CH

_krN
H cyclopropy1 CH3CH2 H Me N
H cyclopropyl CH3CH2CH2 H MeCH

11 N)Y
H cyclopropyl Isopropyl H Me o H cyclopropyl t-butyl H MeCH

H cyclopropyl Vinyl H Me CH

N 'kr R3" R2 R3 R R5 Rb R7 Compound Double bond configuration as per drawing H _____________________________________ cyclopropyl Allyl ____________________________________ H Me N
H cyclopropyl CH2 __ H Me Cyclo-Propyl OP. NAV
H cyclopropyl Butyl H Me CH
SO
H cyclopropyl Sec-butyl H Me NjtV
H cyclopropyl CH3 H Me Me 0 7H)H7 H cyclopropyl CH3CH2 H Me Me 0 H ______________________________________________________ cyclopropyl CH3CH2CH2 H Me __ Me 0 cyclopropyl Isopropyl H Me - Me H cyclopropyl t-butyl H
Me __ Me -41\
H cyclopropyl Vinyl H Me Me 0 R R R R' R R' R7 Compound Double bond configuration as per drawing H cyclopropyl Allyl H
Me Me 0 H cyclopropyl CH2 -H Me Me 0 _ D
Cyclo-Propyl ) H cyclopropyl Butyl H
Me Me 0 _ 4>-NAT7 H _______________________________________________ cyclopropyl Sec-butyl H Me Me 0 *
H c- yclopropyl CH3 H H
410 IIII'V _ ''''CH
H - cyclopropyl CH3CH2 H H o .
CH
'H 'cyclopropyl CH3CH2CH2 H __________ H
410 0/. N-jV
H cyclopropyl Isopropyl H H o CH
_ .
H
cyclopropyl t-butyl H H o CH
, H cyclopropyl Vinyl H H
v''CH 410 )1/7 , H cyclopropyl Allyl H
H III II ' ,11JY _ 'CH
./''=,../L.,.

H cyclopropyl CH2 H H ---'-'CH o Cyclo-Propyl R R R R" R Ft R7 Compound Double bond configuration as per drawing H cyclopropyl Butyl H H ("¨NCH
N'jY
H cyclopropyl Sec-butyl H H
N
,T) H cyclopropyl CH3 H H CH
rA,ro H cyclopropyl CH3CH2 H H CH

N 'jY
H __________________________________________________________________ cyclopropyl CH3CH2CH2 H H

H cyclopropyl Isopropyl -H -H CH

Nr1)7 H cyclopropyl t-butyl H H
H cyclopropyl Vinyl H H

N .)Y

R R R R' R R R7 Compound Double bond configuration as per drawing _ H ______________________________ cyclopropyl Allyl _________________________________ H H
N )Y
..,) _______________________________________________________________________________ _____ _ H cyclopropyl CH2 'H H 7.r'CH
Cyclo-Propyl o N -Kr tr' _ _______________________________________________________________________________ ____ H cyclopropyl Butyl H H -.-'CH _ H cyclopropyl Sec-butyl H H
'-'-''CH
o _IvN
H H CH3 '1-1 Me --7--CH o -k.
_ H H CH3CH2 H Me ___________ CH ____ si ) _ _ _ H H CH3CH2CH2 H Me /'''CH
WL
,-) H H Isopropyl H Me -r'''CH ii III,,L, _ __________________________________________________________ H H t-butyl H Me '''''CH

o _______________________________________________________________________________ ______ H H Vinyl H Me R R R R' R EV R7 Compound Double bond configuration as per drawing H H Allyl H Me CH o t,1).
)\

o H H CH2 H Me 7''NCH
Cyclo-Propyl o H H Butyl H Me ,) _ _______________________________________________________________________________ ____________ - H H Sec-butyl H Me --'''CH
/``=,..'---v 0 N)() I
_ _______________________________________________________________________________ ____________ _ _________ -H H CH3 H Me 0. Ny.i I
_ H H CH3CH2 H Me CH
/.--NI-) _ H H CH3CH2CH2 H Me CH
SO
10. I=A''' H H Isopropyl H Me CH
--.,.,- el o. N:k H H t-butyl H Me ,CH
1110 , o 0.
NJ
k Double bond configuration as per drawing H H Vinyl H Me ''''''CH
v----..,v so tsri H 1-1 Allyl H Me 'CH
so ) i _ __ _ -H H CH2 H Me r7-CH
Cyclo-,'=-=./-Propyl o Isrk Vj , H H Butyl H Me CH

1- NI`
.)) H H Sec-butyl H Me CH
-, ----,=..,,--NiD.
'I) I

-k.
_ ?
H H CH3CH2 H H ''CH
) H H CH3CH2CH2 H H ,7-''CH
isli).L' H H Isopropyl H H

H H t-butyl H H CH

R1 R2 R3 R4 Rb R6 R7 Compound Double bond configuration as per drawing _ _ -o H H Vinyl H H
410 0. NJ1''-.
o - H H Allyl H H 7r'CH
, ) _ .

Cyclo- 40 111 WiL"
,7,=-=,,,,/
Propyl 'T) .
.
o H H Butyl H H ''''CH
40 01. N)L' ' H H Sec-butyl H H 7--CH
NI
..-) _ _ -' H H CH3CH2 H H .
So Ps. tsrj.
) _ _ 0 o OP. N)L'=
) -' H H Isopropyl H H 'CH
So /C.
H H t-butyl H H 7CH
-;>I\

R R R R' R R R7 Compound Double bond configuration as per drawing H H Vinyl H H 7--CH
010 o N'IL' _______________________________________________________________________________ ______ _ H H Allyl H H 7'-`CH
110 o _ H H CH2 H H 'CH
Cyclo----"..-7'--,.
Propyl o __ _ ______________________________________________________ i H H ' Butyl H H -.CH
110 o Isrl .) 1 t H H Sec-Butyl H H -"--CH
o ).,.
SIP N
, Me H CH3 H H cH3 CH2cH=cHcH2 cH2 \ ri\ oN /
CH3CH2CH=CHCH2CH2 Me H CH3CH2 H H
---\_"-A-N
, 7-1Te __ H CH3CH2CH2 H H
CH3CH2CH=CHCH2CH2 0 /
--\ F-A---N
=
Me H Isopropyl H H CH3 CH2CHCHCH2 CH2 --\_/-1\--N
) , Me H t -butyl H H CH3CH2CH=CHCH2CH2 ¨\_"--A\\---N
-.--R R R R. R Ft R7 Compound Double bond configuration as per drawing _ Me H Vinyl H H ail a-120-1=oicH2cH2 1 _____ .
- _________________________________________________________ Me H Allyl H H ,-CH3 CH2CH=CHCH2 CH2 o /
N
- _________________________________________________________ Me H 0H2 H H CH3 CH2CH=CHCH2 CH2 propyl Me H Butyl H H CH3 CH2CH=CHCH2 CH2 ---N
/
r-A--oN
Me H Sec-butyl H H
cH3 CH2CH=CHCH2 CH2 o /
--\ 7-1\--N
---1---1 CH3 CH2CH=CHCH2 CH2 Me H CH3 H H ----/¨\----\7\_3, i N\
Me H CH3CH2 H H CH3 CH2CH=CHCH2 CH2 --/=\---\v\_3 /
N
Me H CH3CH2CH2 H H CH3 CH2CH=CHCH2 CH2 N

3 =
Me H Isopropyl H H
CHCH2CHCHCH2 CH2 ---7¨\---:
/
N
)----Me H t-butyl H H CH3 cH2cx=cHC1-12 CH2 --/-=\---\\7\A-/
N
)-Me H Vinyl H H CH, CH2CH=CHCH2 CH2 ¨r=\----\v\_ro /
N
Me H Allyl H H CH3 CH2CH=CHCH2 CH2 --1---\---\77\_% /
N

___ R R R R' R R. R7 Compound Double bond configuration -.as per drawing _ -Me H CH2 H H cH3 cH2cH---cticH2 cH2 --2/¨\--\\7\_o Cyclo- /
N
p r opy 1 K? 1 Me H Butyl H H CH3 CH2CH=CHCH2 CH2 /¨\---\v\_0 /
/
N
_ _________ -_______________________________________________________________________________ =
Me H Sec-butyl H
H CH3 CH2CHCHCH2 CH2 /=\__\\7\_0, /
--__ _ _______________________________________________________________________________ ___________ cH3 cH2CH-cHcH2 CH2 A o N
-\ _______ .
_ _________ --\---fµl _ _______________________________________________________________________________ ______________ _ H C1-I3 CH2CH=CHCH2 CH2 0 ----H H Isopropyl H H
CH3 CH2CH=CHCH2 CH2 0 , H H t -butyl H H - CH3 CH2CH=CHCH2 CH2 0 I
i _______________________________________________________________________________ ____________ _ H H Vinyl H H
CH3 CH2CH=CHCH2 CH2 o ?
_ _ H H Allyl H H
cH3 CH2CH=CHCH2 CH2 H H CH2 Cy c 1 o H H cH3 cH2cH=cHcH2 CH2 o -propyl _______________________________________________________________________________ _______________ _ - _________________________________________________________________ H ' H Butyl H H
CH3 CH2CH--cHCH2 CH2 >-R1 ----R2 ' R3 R4 R6 R6 _______________ R7 Compound Double bond configuration as per drawing _ --\_/¨A--N
----N\
H H CH 3 CH2 H H CH3 CH2CH=CHCH2CH2 ?
) _ _______________________________________________________________________________ ______ (:) ----[-\--- - V -N ).
H H Isopropyl H H CH3 CH2CH=CHCH2 CH2 %

)----H H t-butyl H H cH3 cH2CH=cHCH2 CH2 o - _ H H Vinyl H H CH3CH2CH=CHCH2CH2 %
H H Ally' H H CH3CH2CHHCH2CH2 N
_ H H CH2 - H H cH3 cH2cH---cHCH2 CH2 ¨

Cyclo-propyl N
?
H ' H Butyl H H CH, CH2CH=CHCH2CH2 N
_ H H Sec-butyl H H CH3 CH2cH=cHcH2 cH2 _f_¨_\___\7\_o N
----Other compounds of the present invention include the following according to Structure 5 above:
R R R R' R R' R7 Compound Double bond configuration drawing H
per rawing _ _______________________________________________________________________________ _______ .
H cyclopropyl H H He (CH3)2 C=CHCH2CH2 H
.
H H CH=CH2 H H Me (CH3)2 C=CHCH2CH2 H
_______________________________________________________________________________ ________ .
.
H H CH(CH3)2 H H Me (CH3)2 C=CHCH2CH2 H
H H H H H Me (CH3) 2 C=CHCH2CH2 H
H H Me H H He (CH3) 2 C=CHCH2CH2 0 ,-',..--=<01., H
H Me Me H H Me (CH3) 2 C=CHCH2CH2 H
H Cyclopropyl H H
H CH3CH2 CH=CHCH2CH2 0 N
N
H
H H H He H H CH3CH:
CH=CHCH2CH2 '. o N
I
The following compounds and Chemical Abstract (CA) names are provided for various compounds of the present invention.
Compound # Structure (Novel compounds) CA Index Name 2,6-nonadienamide, N-[(2E)-3,7--- ---- N)t----..-- --,'N
Fi dimethy1-2,6-octadieny1]-, (2E, 6Z)----L'I\j= -.- 2,6-nonadienamide, N-[(2Z)-3,7-H dimethy1-2,6-octadieny1]-, (2E,6Z)-. _________________________________________________ _ _____________ O 2,6-octadienamide, N-[(2E)-3,7-3 dimethy1-2,6-octadieny1]-3,7-N
H dimethyl-, (2E)-_ _____________ .- 2,6-octadienamide, N-[(2Z)-3,7-4 o dimethy1-2,6-octadieny1]-3,7-H dimethyl-, (2E)-mow _________________ Compound # Structure (Novel compounds) CA Index Name 2,6-octadienamide, dimethy1-2,6-octadieny1]-3,7-dimethyl-, (2Z)-0 2,6-octadienamide, N-[(2Z)-3,7-6 dimethy1-2,6-octadieny1)-3,7-NN
dimethyl-, (2Z)-2,6-octadienamide, 3,7-dimethyl-N-, [(2Z,6Z)-2,6-nonadieny1]-, (2E)-rN)N
2,6-octadienamide, N
[(2Z,6Z)-2,6-nonadieny1]-, (2Z)-, o Cyclopropanecarboxamide, N
[(2Z,6Z)-2,6-nonadieny1]-Cyclopropanecarboxamide, N-H [ (2E, 6Z) -2, 6-nonadienyl ]

Cyclopropanecarboxamide, N-P2E)-3-(3-cyclohexen-1-y1)-2-propeny1]-NN) Cyclopropanecarboxamide, N-[(2Z)-3-H V (3-cyclohexen-1-y1)-2-propeny1]-vi )'r Cyclopropanecarboxamide, N-[(2E)-2-methy1-3-pheny1-2-propeny1]-=

Cyclopropanecarboxamide, N-[(2Z)-2-N 0)1 __________________________________________________________ methyl-3-pheny1-2-propeny1]-V1)Y Cyclopropanecarboxamide, N-[(2E)-3-pheny1-2-buteny1]-=

Cyclopropanecarboxamide, N-[(2Z)-3-0)\17 __________________________________________________________ pheny1-2-buteny1)-(_)-1 Cyclopropanecarboxamide, N-[(2Z,6Z)-2-methy1-2,6-nonadieny1]-Compound # Structure (Novel compounds) CA Index Name Cyclopropanecarboxamide, N-H V [(2E,6Z)-2-methy1-2,6-nonadieny1]-19 N)INIr Cyclopropanecarboxamide, N-[(2E)-3-i pheny1-2-propeny1]-Cyclopropanecarboxamide, N-[(2Z)-3-___________________________________________________ pheny1-2-propeny1]-21 'k<
Propanamide, N-[(2E)-3,7-dimethy1-2,6-octadieny1]-2,2-dimethyl-o NwitN( Propanamide, N-[(2Z)-3,7-dimethyl-H 2,6-octadieny1]-2,2-dimethyl-N Butanamide, N-[(2E)-3,7-dimethyl-H 2,6-octadieny1]-N Butanamide, N-[(2Z)-3,7-dimethyl-H 2,6-octadieny1]-Propanamide, N-[(2E)-2-methy1-3-pheny1-2-propeny1]-N Propanamide, N-[(2Z)-2-methy1-3-pheny1-2-propeny1]-Propanamide, N-[(2E)-3-pheny1-2-buteny1]-Propanamide, N-[(2Z)-3-pheny1-2-H buteny1]-2 9 ,k, 40 Acetamide, N-H2E)-2-methyl-3-phenyl-2-propenyl]-Compound if. Structure (Novel compounds) CA Index Name N, Nr?' Acetamide, N-[(2Z)-2-methy1-3-pheny1-2-propeny1]-Olt N
Acetamide, N-[(2E)-3-pheny1-2-buteny1]-N Acetamide, N-[(2Z)-3-pheny1-2-H buteny1]-33 Acetamide, N-[(2Z,6Z)-2-methy1-2,6---\--/
nonadieny1]-Acetamide, N-[(2E,6Z)-2-methy1-2,6-H nonadieny1]-" Propanamide, N-[(2E)-3-(3-cyclohexen-1-y1)-2-propeny1)-SO

Propanamide, N-[(2Z)-3-(3-H cyclohexen-l-y1)-2-propeny1]-N
Acetamide, N-[(2E)-3-(3-cyclohexen-1-y1)-2-propenyll-SO

N Acetamide, N-[(2Z)-3-(3-cyclohexen-H 1-y1)-2-propeny1]-Propanamide, 39 cyclohexen-l-y1)-2-propeny1]-2,2-dimethyl-410Propanamide, cyclohexen-1-y1)-2-propeny1]-2,2-dimethyl-Butanamide, N-[(2E)-3,7-dimethyl-H
2,6-octadieny1]-2-methyl-Compound # Structure (Novel compounds) CA Index Name 42 (o r4). Butanamide, N-[(2Z)-3,7-dimethyl-H
2,6-octadieny1]-2-methyl-43 Cyclopropanecarboxamide, N-[(2E)-il / 3,7-dimethy1-2,6-octadieny1]-44 Cyclopropanecarboxamide, N-[(2Z)-3,7-dimethy1-2,6-octadienyll-45 Propanamide, N-[(2E)-3,7-dimethyl-H 2,6-octadieny1]-2-methyl-o Propanamide, N-[(2Z)-3,7-dimethyl-H 2,6-octadieny1]-2-methyl-2-butenamide, N-[(2E)-3,7-dimethyl-H
2,6-octadieny1]-, (2E)-N 2-butenamide, N-[(2Z)-3,7-dimethyl-H 2,6-octadienyl]-, (2E)-2-butenamide, N-[(2E)-3,7-dimethyl-H 2,6-octadieny1]-3-methyl-50 2-butenamide, N-[(2Z)-3,7-dimethyl-2,6-octadieny1]-3-methyl-Cyclopropanecarboxamide, N-H V [(2E,6Z)-2,6-dodecadieny1]-Cyclopropanecarboxamide, N-[(2E)-3-r14)''7 (4-methy1-3-cyclohexen-1-y1)-2-buteny1]-53 40 Cyclopropanecarboxamide, H V

Compound # Structure (Novel compounds) CA Index Name 54N-Jj\7 Cyclopropanecarboxamide, N-(3-_ methyl-2-buteny1)-Cyclopropanecarboxamide, N-[ (2E)--55 ";7 (2,6,6-trimethy1-3-cyclohexen-y1)-2-butenyll-Cyclopropanecarboxamide, N-[(2Z)-3-56(2,6,6-trimethy1-3-cyclohexen-1-ri,J1.17 y1)-2-buteny1]-40 N. J17 Cyclopropanecarboxamide, N-[(2E)-3-57 (2,4-dimethy1-3-cyclohexen-1-y1)-2-propeny1]-:11`,4 Cyclopropanecarboxamide, N-[(2Z)-3-(2,4-dimethy1-3-cyclohexen-1-y1)-2-H / propenyi]-59 ,JL
Acetamide, N-[(2E)-3-(4-methy1-3-cyclohexen-1-y1)-2-buteny1]-Acetamide, N-[(2Z)-3-(4-methyl-3-H cyclohexen-1-y1)-2-buteny1]-III
Acetamide, N-[(2E)-3-(2,6,6-61 trimethy1-3-cyclohexen-1-y1)-butenylj-Acetamide, N-[(2Z)-3-(2,6,6-trimethy1-3-cyclohexen-1-y1)-2-buteny1]-Acetamide, N-[(2E)-3-(2,4-dimethy1-3-cyclohexen-1-y1)-2-propenyll-64 =
N)1 Acetamide, N-[(2Z)-3-(2,4-dimethyl-H 3-cyclohexen-l-y1)-2-propeny1]-0 Cyclopropanecarboxamide, N-[[2-methy1-2-(4-methy1-3-pentenyl)cyclopropyl]methy1]-, Compound # Structure (Novel compounds) CA Index Name o Cyclopropanecarboxamide, N-([2-;..õ,-1111,.N.-1-Lv. [(3Z)-3-H
hexenyl]cyclopropyl]methy1]- _ ,-N
-N. 0 c)C/ Propanamide, N-[(2Z)-3,7-dimethyl-H 2,6-octadieny1]-"../N" 0 70 Acetamide, N-[(2Z)-3,7-dimethyl-H 2,6-octadienyl]-71 o Cyclopropanecarboxamide, N-methyl-N-[(2Z,6Z)-2,6-nonadieny1]-\
72 \ A ________________________________________________ Cyclopropanecarboxamide, N-ethyl-N-7---N [(2Z,6Z)-2,6-nonadieny1]-73 _ o, A _____ Cyclopropanecarboxamide, N-[(2Z,6Z)-2,6-nonadienyl]-N-propyl-- \.--7-j¨ \ --(:) N\----\
_______________________________________________________________________________ _______________ _ -o Cyclopropanecarboxamide, N-(1-74 _ \_7----N methylethyl) -N-[(2Z,6Z)-2,6----\\=/¨/ nonadieny1]-75 _ R, A
Cyclopropanecarboxamide, N-(1,1-dimethylethyl) -N-[(2Z,6Z)-2,6---\__ --)\ nonadienyl]-76 _ , A
Cyclopropanecarboxamide, N-ethenyl-N-[(2Z,6Z)-2,6-nonadieny1]-Cyclopropanecarboxamide, N--N_N/ N [(2Z,6Z)-2,6-nonadieny1]-N-(2---,v_ propeny1)-_78 cH __________________________________________________ Cyclopropanecarboxamide, N-(cyclopropylmethyl) -N-[(2Z,6Z)-___________________________________________ a.
--\.:=7-1 __________________________________ \¨ 2,6-nonadienyl]--Cyclopropanecarboxamide, N-butyl-N-79 R, A
[(2Z,6Z)-2,6-nonadieny1]-----\¨ \----',.-Compound # Structure (Novel compounds) CA Index Name Cyclopropanecarboxamide, [(2Z,6Z)-2,6-nonadienyl] -N-(2-methylpropyl) 81 Cyclopropanecarboxamide, N-methyl-N-[(2E,6Z)-2,6-nonadieny1]-82 Cyclopropanecarboxamide, N-ethyl-N-wN
[(2E,6Z)-2,6-nonadieny1]-83 o Cyclopropanecarboxamide, N-[(2E,6Z)-2,6-nonadieny1]-N-propyl-84 Cyclopropanecarboxamide, N-(1-methylethyl) -N-[(2E,6Z) -2,6-nonadieny1]-Cyclopropanecarboxamide, N-(1,1-dimethylethyl)- N-[(2E,6Z)-2,6-W ) nonadienyl] -86 Cyclopropanecarboxamide, N-ethenyl-N-[(2E,6Z)-2,6-nonadienyl] -87 ,õ
Cyclopropanecarboxamide, N-[(2E,6Z)-2,6-nonadieny1]-N-(2-N)Y
propeny1)-Cyclopropanecarboxamide, N-(cyclopropylmethyl) -N-[(2E,6Z)-2, 6-nonadienyl] -89 Cyclopropanecarboxamide, N-butyl-N-[(2E,6Z)-2,6-nonadieny1]-Cyclopropanecarboxamide, N-[(2E,6Z)-2,6-nonadieny1]-N-(2-methylpropy1)-91 Cyclopropanecarboxamide, N-methyl-00 11\)t.T/ N-[(2E)-3-(3-cyclohexen-l-y1)-2-propeny1]-Compound # Structure (Novel compounds) CA Index Name _______________________________________________________________________________ ________ _ 92 Cyclopropanecarboxamide, N-ethyl-40 is N-[(2E)-3-(3-cyclohexen-l-y1)-2-propeny1]-93 .
_______________________________________________________________________________ ________ _ o Cyclopropanecarboxamide, N-[(2E)-3-r7WN-jir (3-cyclohexen-1-y1)-2-propeny1]-N-L, propyl o . Cyclopropanecarboxamide, N-(1-0 :IjL117 95 methylethyl)- N-[(2E)-3-(3-cyclohexen-l-y1)-2-propeny1]-o Cyclopropanecarboxamide, N-(1,1-410N-17dimethylethyl)-N-[(2E)-3-(3-cyclohexen-l-y1)-2---.,\
propeny1]-o Cyclopropanecarboxamide, N-ethenyl-010 I\C- N-[(2E)-3-(3-cyclohexen-1-y1)-2-propeny1]--_ ___________________________________ o Cyclopropanecarboxamide, N-[(2E)-3-(3-cyclohexen-1-y1)-2-propeny1]-N-010 Is4T17 (2-propeny1)-_______________________________________________________________________________ ________ _ o Cyclopropanecarboxamide, N-410 rel7 (cyclopropylmethyl) - N-[(2E)-3-(3-cyclohexen-l-y1)-2-propenyll-o Cyclopropanecarboxamide, N-butyl-N-N'-17[(2E)-3-(3-cyclohexen-1-y1)-2-propeny1]--100 Cyclopropanecarboxamide, N-[(2E)-3-NIT/ (3-cyclohexen-l-y1)-2-propeny1]-N-410 's"----/ (2-methylpropy1)-__________________ _ ______________________________ 410 o Cyclopropanecarboxamide, N-methyl-N-[(2Z)-3-(3-cyclohexen-1-y1)-2-propeny1]-I
010 o Cyclopropanecarboxamide, N-ethyl-N-[(2Z)-3-(3-cyclohexen-1-y1)-2-propeny1]-NAT/
_ __________________________________________________ _ _________________ Cyclopropanecarboxamide, N-[(2Z)-3-010(3-cyclohexen-1-y1)-2-propeny1]-N-0 propyl-\ N)(T7 rj Compound # Structure (Novel compounds) CA Index Name 410 ________________________________________________ Cyclopropanecarboxamide, N-(1-methy1ethyl)-N-[(2Z)-3-(3-cyclohexen-1-y1)-2-propeny1]-N)LTI7 ¨105 Cyclopropanecarboxamide, N-(1,1-o dimethylethyl)-N-[(2Z)-3-(3-cyclohexen-l-y1)-2-propeny1]-Cyclopropanecarboxamide, N-ethenyl-N-[(2Z)-3-(3-cyclohexen-l-y1)-2-propenyli-Cyclopropanecarboxamide, N-[(2Z)-3-(3-cyclohexen-1-y1)-2-propeny1]-N-o (2-propeny1)-\ N )(I( \
110 Cyclopropanecarboxamide, N-(cyclopropylmethy1)- N-[(2Z)-3-(3-cyclohexen-1-y1)-2-propeny1]--kv Cyclopropanecarboxamide, N-butyl-N--110 [(2Z)-3-(3-cyclohexen-1-y1)-2-propeny1]-N(ILT7 110 ________________________________________________ Cyclopropanecarboxamide, N-[(2Z)-3-(3-cyclohexen-1-y1)-2-propeny1]-N-(2-methylpropy1)-)1.T7 111 Cyclopropanecarboxamide, N-methyl-N-[(2E)-2-methy1-3-pheny1-2-propeny1]-112 o ___________ Cyclopropanecarboxamide, N-ethyl-N-01$ NA-V [(2E)-2-methy1-3-pheny1-propeny1]-Na70 113 Cyclopropanecarboxamide, N-[(2E)-2-methy1-3-pheny1-2-propenyl]-N-propyl Compound # Structure (Novel compounds) CA Index Name _______________________________________________________________________________ _________ _ 114 ___ O Cyclopropanecarboxamide, N-(1-010 :1-1,51 methylethyl)- N-[(2E)-2-methy1-3-phenyl-2-propeny1]-_ 0 , t*,a7 Cyclopropanecarboxamide, N-(1,1-' dimethylethyl)-N-[(2E)-2-methy1-3-phenyl-2-propeny1]-o Cyclopropanecarboxamide, N-ethenyl-410 s' .1N-[(2E)-2-methy1-3-pheny1-2-propeny1]-o Cyclopropanecarboxamide, N-[(2E)-2-lit N) methyl-3-phenyl-2-propenyl]-N-(2-CT/...= propeny1)-o Cyclopropanecarboxamide, N-[(2E)-2-010 _____________________________________________ methy1-3-pheny1-2-propenyl]-N-(cyclopropylmethyl)-o 119 Cyclopropanecarboxamide, N-butyl-N-Olt r/7 [(2E)-2-methy1-3-phenyl-propeny1]-o Cyclopropanecarboxamide, N¨[(2E)-2¨
110 11.)7 methyl-3-phenyl-2-propenyl]-N-(2-c) methylpropy1)-010 _________________________________________________ Cyclopropanecarboxamide, N-methyl-N-[(2Z)-2-methy1-3-pheny1-2-propeny1]-NJL=7 I , 5o Cyclopropanecarboxamide, N-ethyl-N-[(2Z)-2-methyl-3-phenyl-2-propeny1]-N-17, 110 _________________________________________________ Cyclopropanecarboxamide, N-[(2Z)-2-methy1-3-pheny1-2-propenyl]-N-o propyl N,-It.7 410 o Cyclopropanecarboxamide, N¨(1¨

methylethyl)- N-[(2Z)-2-methyl-3-phenyl-2-propeny1]-NI)Lv /,.
=

Compound # Structure (Novel compounds) CA Index Name 410 _______________________________________________ Cyclopropanecarboxamide, N-(1,1-dimethylethyl)-N-[(2Z)-2-methy1-3-pheny1-2-propeny1]-126 Cyclopropanecarboxamide, N-etheny1-N-C(2Z)-2-methy1-3-pheny1-2-propenyll-410 Cyclopropanecarboxamide, N-[(2Z)-2-methyl-3-phenyl-2-propenyl]-N-(2-1 propeny1)-( 410 Cyclopropanecarboxamide, N-(cyclopropylmethyl) methyl-3-phenyl-2-propenyl]-L.T7 410 _______________________________________________ Cyclopropanecarboxamide, N-buty1-N-[(2Z)-2-methyl-3-phenyl-2-N
propeny1]-Cyclopropanecarboxamide, N-[(2Z)-2-methy1-3-phenyl-2-propenyl]-N-(2-)Lõv Ly.. methylpropy1)-Cyclopropanecarboxamide, N-[(2E)-3-pheny1-2-buteny1]-N-methyl-Cyclopropanecarboxamide, N-[(2E)-3-pheny1-2-buteny1]-N-ethyl-Cyclopropanecarboxamide, N-[(2E)-3-pheny1-2-butenyl]-N-propyl-Compound # Structure (Novel compounds) CA Index Name Cyclopropanecarboxamide, N-[ (2E)-3-010 pheny1-2-buteny1]-N-(1-methylethyl)-135 Cyclopropanecarboxamide, N-[ (2E)-3-1:-/\)17 pheny1-2-buteny1]-N-(1,1-dimethylethyl)-Cyclopropanecarboxamide, N-[ (2E)-3-* pheny1-2-buteny1]-N-ethenyl-Cyclopropanecarboxamide, N-[(2E)-3-N)H7 phenyl-2-buteny1]-N-(2-propeny1)-Cyclopropanecarboxamide, N-[(2E)-3-T<iisl-a.IY pheny1-2-buteny1]-N-(cyclopropylmethyl)-139 Cyclopropanecarboxamide, N-[(2E)-3-010 pheny1-2-butenyll-N-butyl-Cyclopropanecarboxamide, N-[ (2E)-3--_1) N)V pheny1-2-butenyli-N-(2-methylpropy1)-_______________________________________________________________________________ ___ Cyclopropanecarboxamide, N-[(2Z)-3-pheny1-2-butenyll-N-methyl-142 _______________ _______________________________________________________________________________ ___ Cyclopropanecarboxamide, N-[(2Z)-3-pheny1-2-buteny1]-N-ethyl-1,1)Y

_______________________________________________________________________________ ______ 410 Cyclopropanecarboxamide, N-[(2Z)-3-pheny1-2-butenyll-N-propyl-N)LV
Cyclopropanecarboxamide, N-[ (2Z)-3-phenyl-2-buteny1]-N-(1-methylethyl)-N)LT7 Compound # Structure (Novel compounds) CA Index Name _______________________________________________________________________________ ____ Cyclopropanecarboxamide, N-[(2Z)-3-pheny1-2-buteny1]-N-(1,1-dimethylethyl)-N.kcre _______________________________________________________________________________ ____ Cyclopropanecarboxamide, N-[(2Z)-3-pheny1-2-buteny1]-N-ethenyl-_______________________________________________________________________________ ____ Cyclopropanecarboxamide, N-[(2Z)-3-phenyl-2-buteny1]-N-(2-propeny1)-Cyclopropanecarboxamide, N-[(2Z)-3-pheny1-2-buteny1]-N-(cyclopropylmethyl)-Cyclopropanecarboxamide, N-[(2Z)-3-pheny1-2-butenyl]-N-butyl-110 Cyclopropanecarboxamide, N-{ (2Z)-3-phenyl-2-buteny1]-N-(2-methylpropy1)-N )11 151 Cyclopropanecarboxamide, N-methyl-N-[(2Z,6Z)-2-methy1-2,6-nonadienyll-N Cyclopropanecarboxamide, N-ethyl-N-[(2Z,6Z)-2-methy1-2,6-nonadieny1]-153 Cyclopropanecarboxamide, N-[(2Z,6Z)-2-methy1-2,6-nonadienyl]-N-propyl-154 Cyclopropanecarboxamide, N-(1-methylethyl)- N-[(2Z,6Z)-2-methyl-2,6-nonadieny1]-Compound # Structure (Novel compounds) CA Index Name , ¨\¨/¨/--Nµi N
Cyclopropanecarboxamide, N-( 2-155 --) I2 N-[(2Z,6Z)-2-methy1-2,6-nonadienyl]-, n Cyclopropanecarboxamide, N-ethenyl-156 ' N-[(2Z,6Z)-2-methy1-2,6-nonadieny1]-157 /--/¨(-N
(:).A Cyclopropanecarboxamide, N-[(2Z,6Z)-2-methy1-2,6-nonadieny1]-N-(2-propeny1)-158 oH Cyclopropanecarboxamide, N-/¨ (cyclopropylmethyl) -N-[(2Z,6Z)-2-methy1-2,6-nonadieny1]-159 oH Cyclopropanecarboxamide, N-butyl-N-[(2Z,6Z)-2-methy1-2,6-nonadieny1]-160 /--/ ¨ (--o Cyclopropanecarboxamide, N-[(2Z,6Z)-2-methy1-2,6-nonadieny1]----,\_ I N-(2-methylpropy1)-, 161 ..,0 Cyclopropanecarboxamide, N-methyl-N-[(2E,6Z)-2-methy1-2,6-I nonadieny1]-162 -,õ o Cyclopropanecarboxamide, N-ethyl-N-[(2E,6Z)-2-methy1-2,6-nonadienyl].
.) 163 ,, o Cyclopropanecarboxamide, N-[(2E,6Z)-2-methy1-2,6-nonadieny1]-N-propyl-164 -,, o Cyclopropanecarboxamide, N-(1-methylethyl)-N-[(2E,6Z)-2-methyl-2,6-nonadieny1]-165 ,0 Cyclopropanecarboxamide, N-(1,1-dimethylethyl)-N-[(2E,6Z)-2-methy1-2,6-nonadieny1]-166 ,, o Cyclopropanecarboxamide, N-ethenyl-N-7 N-[(2E,6Z)-2-methy1-2,6-nonadienyl]
LI-..,...

Compound # Structure (Novel compounds) CA Index Name 167 Cyclopropanecarboxamide, N-[(2E,6Z)-2-methy1-2,6-nonadieny1]-N-(2-propeny1)-Cyclopropanecarboxamide, N-(cyclopropylmethyl) -N-[(2E,6Z)-2-WN)L.T7 methy1-2,6-nonadienyl]-169 Cyclopropanecarboxamide, N-butyl-N-[(2E,6Z)-2-methy1-2,6-nonadieny1]-170 Cyclopropanecarboxamide, N-[(2E,6Z)-2-methy1-2,6-nonadienyl]-N-(2-methylpropy1)-171 Cyclopropanecarboxamide, N-methyl-N-Jy, N-[(2E)-3-pheny1-2-propeny1]-172 Cyclopropanecarboxamide, __________ 410 YII7 [(2E)-3-pheny1-2-propeny1]-Cyclopropanecarboxamide, N-[(2E)-3-_____________________________________________________ 1 OltFs17 pheny1-2-propeny1]-N-propyl-Cyclopropanecarboxamide, N-(1-410 /7\):7 methylethyl)-N-[(2E)-3-pheny1-2-propenyll-175 Cyclopropanecarboxamide, N-(1,1-010 4T7 dimethylethyl)- N-[(2E)-3-pheny1-2-propeny1]-176 Cyclopropanecarboxamide, N-ethenyl-177 N-[(2E)-3-pheny1-2-propeny1]-Cyclopropanecarboxamide, N-[(2E)-3-410 NA-V pheny1-2-propeny1]-N-178 (2-propeny1)-0 Cyclopropanecarboxamide, N-T<JI)IN'V (cyclopropylmethyl) -N-[(2E)-3-phenyl-2-propeny1]-Compound # Structure (Novel compounds) CA Index Name Cyclopropanecarboxamide, N-butyl-N-.sjjLi7 [(2E)-3-phenyl-2-propeny1]-Cyclopropanecarboxamide, N-[(2E)-3-411 .4'1)117 pheny1-2-propenyll-N-(2-methylpropy1)-410 Cyclopropanecarboxamide, N-methyl-N-[(2Z)-3-pheny1-2-propeny1]-N)1I7 Cyclopropanecarboxamide, N-ethyl-N-[(2Z)-3-pheny1-2-propeny1]-010 Cyclopropanecarboxamide, N-[(2Z)-3-pheny1-2-propeny1]-N-propyl-184 Cyclopropanecarboxamide, N-(1-methylethyl)-N-[(2Z)-3-pheny1-2-o propenyll-410 Cyclopropanecarboxamide, N-(1,1-dimethylethyl)- N-[(2Z)-3-pheny1-2-propenyll-N

410 0 Cyclopropanecarboxamide, N-ethenyl-N-[(2Z)-3-pheny1-2-propenyl]-N ' 410 0 Cyclopropanecarboxamide, N-[(2Z)-3-pheny1-2-propeny1]-N-2-propenyl-N

Compound # Structure (Novel compounds) CA Index Name 110 _______________________________________________ Cyclopropanecarboxamide, N-(cyclopropylmethyl) -N-[(2Z)-3-pheny1-2-propenyl]-N)T7 _____________________________________________________________________________ 110 Cyclopropanecarboxamide, N-butyl-N-[(2Z)-3-pheny1-2-propeny1]-NA,V

_______________________________________________________________________________ __ 410 Cyclopropanecarboxamide, N-[(2Z)-3-pheny1-2-propeny1i-N-(2-methylpropy1)-N
H1919 Propanamide, N-methyl-N-[(2E)-3,7-N)Y dimethy1-2,6-octadieny1]-2,2-dimethy1-Propanamide, N-ethyl-N-[(2E)-3,7-dimethy1-2,6-octadieny1]-2,2-dimethyl-193 1 Propanamide, N-[(2E)-3,7-dimethy1-2,6-octadieny1]-N-propyl-2,2-Nx( dimethyl-Propanamide, N-(1-methylethyl)-N-[(2E)-3,7-dimethy1-2,6-octadieny1]-I 2,2-dimethyl-195 9 Propanamide, N-(1,1-dimethylethyl)-N-[(2E)-3,7-dimethy1-2,6-octadieny1]-2,2-dimethyl-Propanamide, N-ethenyl-N-[(2E)-3,7-dimethy1-2,6-octadieny1]-2,2-dimethyl-197 Propanamide, N-[(2E)-3,7-dimethyl--. 2,6-octadieny1]-N-(2-propeny1)-2,2-dimethyl-Propanamide, N-(cyclopropylmethyl)-)H< N-[(2E)-3,7-dimethy1-2,6-octadieny1]-2,2-dimethyl-Compound # Structure (Novel compounds) CA Index Name -Propanamide, N-butyl-N-[(2E)-3,7 dimethy1-2,6-octadieny1]-2,2-dimethyl-Propanamide, N-[(2E)-3,7-dimethyl-2,6-octadienyl]-N-(2-methylpropy1)---Kj 2,2-dimethyl-201 Propanamide, N-methyl-N-[(2Z)-3,7-0 dimethy1-2,6-octadieny1]-2,2-NrA- dimethyl-202 Propanamide, N-ethyl-N-[(2Z)-3,7-o dimethy1-2,6-octadieny1]-2,2-dimethyl-203 Propanamide, N-[(2Z)-3,7-dimethyl-o 2,6-octadieny1]-N-propy1-2,2-t=A'<1 dimethyl-204 Propanamide, N-(1-methylethyl)-N-o [(2Z)-3,7-dimethy1-2,6-octadieny1]-2,2-dimethyl-205 Propanamide, N-(1,1-dimethylethyl)-0 N-[(2Z)-3,7-dimethy1-2,6-octadieny1]-2,2-dimethyl-206 Propanamide, 0 dimethy1-2,6-octadieny1]-2,2-dimethyl-207 Propanamide, N-[(2Z)-3,7-dimethyl-. o 2,6-octadieny1]-N-(2-propeny1)-2,2-&LT(. dimethyl-208 Propanamide, N-(cyclopropylmethyl)--- 0 N-[(2Z)-3,7-dimethy1-2,6-octadieny1]-2,2-dimethyl-209 Propanamide, N-butyl-N-[(2Z)-3,7-^ dimethy1-2,6-octadieny1]-2,2-, dimethyl-Compound # Structure (Novel compounds) CA Index Name 210 Propanamide, N-[(2Z)-3,7-dimethyl-o 2,6-octadieny1]-N-(2-methylpropy1)-2,2-dimethy1-211 0 Butanamide, N-methyl-N-[(2E)-3,7-dimethy1-2,6-octadieny1]-N

Butanamide, N-ethyl-N-[(2E)-3,7-dimethy1-2,6-octadieny1]-213 Butanamide, N-[(2E)-3,7-dimethyl-2,6-octadieny1]-N-propyl-Butanamide, N-(1-methylethyl)-N-[(2E)-3,7-dimethy1-2,6-octadieny1]-A
Butanamide, N-(1,1-dimethylethyl)-N-[(2E)-3,7-dimethy1-2,6-octadieny1]-216 I Butanamide, dimethy1-2,6-octadieny1]-o Butanamide, N-[(2E)-3,7-dimethyl-'217 2,6-octadieny1]-N-(2-propeny1)-o Butanamide, N-(cyclopropylmethyl)-N-[(2E)-3,7-dimethy1-2,6-octadieny1]-219 Butanamide, N-butyl-N-[(2E)-3,7-dimethy1-2,6-octadieny1]-o Butanamide, N-[(2E)-3,7-dimethyl-2,6-octadienyl]-N-(2-methylpropy1)-221 Butanamide, N-methyl-N-[(2Z)-3,7-o dimethy1-2,6-octadieny1]-Compound # Structure (Novel compounds) CA Index Name 222 Butanamide, N-ethyl-N-[(2Z)-3,7-o dimethy1-2,6-octadieny1]-223 Butanamide, N-[(2Z)-3,7-dimethyl-0 2,6-octadieny1]-N-propyl-\NA,/
224 Butanamide, N-(1-methylethy1)-N-7, ? [(2Z)-3,7-dimethy1-2,6-octadieny1]-225 Butanamide, N-(1,1-dimethylethyl)-0 N-[(2Z)-3,7-dimethy1-2,6-Lrsl) octadieny1]-Butanamide, N-ethenyl-N-[(2Z)-3,7-dimethy1-2,6-octadieny1]-227 Butanamide, N-[(2Z)-3,7-dimethyl-o 2,6-octadienyll-N-(2-propeny1)-228 Butanamide, N-(cyclopropylmethyl)-0 N-[(2Z)-3,7-dimethy1-2,6-octadieny1]-229 Butanamide, 0 dimethy1-2,6-octadienyll-r7¨N
230 Butanamide, N-[(2Z)-3,7-dimethyl-2,6-octadieny1]-N-(2-methylpropy1)-0 _______________________________________________ 231 Propanamide, N-methyl-N-[(2E)-010 methyl-3-phenyl-2-propeny1]-232 0 Propanamide, N-ethyl-N-[(2E)-2-methy1-3-pheny1-2-propenyl]-Olt NI

Compound # Structure (Novel compounds) GA Index Name Propanamide, N-[(2E)-2-methy1-3-N pheny1-2-propenyll-N-propyl-L, o Propanamide, N-(1-methylethyl)-N-[(2E)-2-methy1-3-pheny1-2-propeny1]-O Propanamide, N-(1,1-dimethylethyl)-N-[(2E)-2-methy1-3-pheny1-2-1.1 propeny1]-o Propanamide, N-ethenyl-N-[(2E)-2-methy1-3-pheny1-2-propenyl]-o Propanamide, N-[(2E)-2-methy1-3-40 pheny1-2-propeny1]-N-(2-propeny1)-o Propanamide, N-(cyclopropylmethyl)-41 2 N-[(2E)-2-methy1-3-pheny1-propeny1]-Propanamide, N-butyl-N-[(2E)-2-410N1 methy1-3-pheny1-2-propeny1]-o Propanamide, N-[(2E)-2-methy1-3-phenyl-2-propeny1]-N-(2-/K)\ methylpropy1)-410 _______________________________________________ Propanamide, N-methyl-N-[(2Z)-2-methyl-3-phenyl-2-propeny1]-410 _______________________________________________ Propanamide, N-ethyl-N-[(2Z)-2-methyl-3-phenyl-2-propeny1]-L, 410 Propanamide, N-[ (2Z)-2-methyl--3--243 pheny1-2-propeny1]-N-propyl-Compound # Structure (Novel compounds) CA Index Name 410 Propanamide, N-(1-methylethyl)-N-[(2Z)-2-methy1-3-pheny1-2-N propenyl] -Propanamide, N-(1-methylethyl)-N-[(2Z)-2-methy1-3-pheny1-2-o propenyl]-Propanamide, N-ethenyl-N-[(2Z)-2-methy1-3-pheny1-2-propenyl]-110 Propanamide, N-[(2Z)-2-methy1-3-pheny1-2-propenyl]-N-2-propenyl-Propanamide, N-(cyclopropylmethyl)-N-[(2Z)-2-methy1-3-pheny1-2-N propeny1]-410 Propanamide, N-butyl-N-[(2Z)-2-methy1-3-pheny1-2-propenyl]-N
250Propanamide, N-[(2Z)-2-methyl-3-'Y
phenyl-2-propeny1]-N-(2-methylpropy1)-Ic Propanamide, N-[(2E) -3-phenyl-2-4111 1,1) buteny1]- N-methyl-Propanamide, N-[(2E) -3-phenyl-2-001 N) butenyl]- N-ethyl-0 Propanamide, N-[(2E) -3-phenyl-2-40 buteny1]-N-propyl-, Compound # Structure (Novel compounds) CA Index Name o 254 Propanamide, N-[(2E) -3-phenyl-2--. ---11...õ--411 ,f,:cl butenyl]-N-(1-methylethyl)-255 nr o Propanamide, N-[(2E) -3-pheny1-2-)Lõ,, buteny1]-N-(1,1-dimethylethyl)-its4 --(---I
o 256 Propanamide, N-[(2E) -3-phenyl-2-41 1,1) buteny1]-N-ethenyl-L,_ o ' 2 5 7 Propanamide, N-[(2E) -3-pheny1-2-0 N '1.-* butenyli-N-(2-propeny1)-t--, , o 258 Propanamide, N-[(2E) -3-pheny1-2----, ---il-,..õ--0 buteny1]-N-(cyclopropylmethyl)-o 259 Propanamide, N-[(2E) -3-phenyl-2--IL.,-260 butenyll-N-butyl-o Propanamide, N-[(2E) -3-phenyl-2-410 o Propanamide, N-[(2Z) -3-pheny1-2-buteny1]-N-methyl-...-------..õ
T

IP o Propanamide, N-[(2Z) -3-pheny1-2-butenyl]-N-ethyl-) ' 263 410 o Propanamide, N-[(2Z) -3-pheny1-2-buteny1]-N-propyl-"--. N

\
\

410 o Propanamide, N-[(2Z) -3-pheny1-2-buteny1]-N-(1-methylethyl)-rsrk-"-Compound # Structure (Novel compounds) CA Index Name _______________________________________________________________________________ ______ 410 Propanamide, N-[(2Z)- 3-pheny1-2-buteny1]-N-(1,1-dimethylethyl)-N

110 ________________________________________________ Propanamide, N-[(2Z) -3-pheny1-2-butenyl]-N-ethenyl-N
1==

110 ________________________________________________ Propanamide, N-[(2Z) -3-pheny1-2-butenyl]-N-(2-propeny1)-= N

410 _______________________________________________ Propanamide, N-[(2Z) -3-pheny1-2-buteny1]-N-(cyclopropy1methyl)-= N

410 ________________________________________________ Propanamide, N-[(2Z)- 3-pheny1-2-butenyl]-N-butyl-N

410 _______________________________________________ Propanamide, N-[(2Z) -3-pheny1-2-buteny1]-N-(2-methylpropy1)-N
271 Acetamide, N-methyl-N-[(2E)-2-ts1 methy1-3-pheny1-2-propenyll-272 Acetamide, N-ethyl-N-[(2E)-2- ______ methy1-3-phenyl-2-propenyl]-273 __________________________ 010 Acetamide, N-[(2E)-2-methy1-3-pheny1-2-propeny1]-N-propyl-274Acetamide, N-(1-methylethyl)-N-411 teiL [(2E)-2-methy1-3-pheny1-propenyl]-Compound # Structure (Novel compounds) CA Index Name o 275 Acetamide, N-(1,1-dimethylethyl)-N-010 ..7:- [(2E)-2-methy1-3-pheny1-2-propeny1]-o Acetamide, N-ethenyl-N-[(2E)-2-' 00 ' wl' -1,.., methy1-3-pheny1-2-propeny1j-o 277 Acetamide, N-[(2E)-2-methyl-3-410 '-'''' phenyl-2-propenyl]-N-(2-propeny1)-o Acetamide, N-(cyclopropylmethyl)-N-.1, [(2E)-2-methy1-3-pheny1-140 propenyll-[L

o Acetamide, N-butyl-N-[(2E)-2-, methy1-3-phenyl-2-propenyl]-olt N- N
\----\----o 280 Acetamide, N-[(2E)-2-methyl-3-Itõ,, pheny1-2-propeny1]-N-(2-methylpropy1)-IP o Acetamide, N-methyl-N-[(2Z)-2-methy1-3-pheny1-2-propenyl]-T
282 Acetamide, N-ethyl-N-[(2Z)-2-0 methy1-3-pheny1-2-propenyl]-'-,-- o -rNA, ) '283 IP o Acetamide, N-[(2Z)-2-methy1-3-phenyl-2-propeny11-N-propyl-IP o Acetamide, N-(1-methy1ethyl)-N-[(2Z)-2-methy1-3-pheny1-2-propeny1]-N'K
)K

IP Acetamide, N-(1,1-dimethylethyl)-N-[(2Z)-2-methyl-3-pheny1-2-N..Ko propeny1]-, .-^

Compound # Structure (Novel compounds) CA Index Name 0 Acetamide, N-ethenyl-N-[(2Z)-2-methy1-3-pheny1-2-propenyll-110 0 Acetamide, N-[(2Z)-2-methyl-3-pheny1-2-propeny1]-N-(2-propeny1)-N
288 __________________________________________ 410 Acetamide, N-(cyclopropylmethyl)-N-[(2Z)-2-methy1-3-pheny1-2-N propenyl]-Acetamide, N-butyl-N-[(2Z)-2-methy1-3-pheny1-2-propenyl]-_______________________________________________________________________________ _ 010 Acetamide, N-[(2Z)-2-methy1-3-phenyl-2-propeny1]-N-(2-0 methylpropy1)-N
Acetamide, N-[(2E)-3-phenyl-2-N buteny1]-N-methyl-Acetamide, N-[(2E)-3-phenyl-2-292 butenyl]-N-ethyl-410 N) Acetamide, N-[(2E)-3-phenyl-2-butenyl]-N-propyl-Acetamide, N-[(2E)-3-phenyl-2-butenyl]-N-(1-methylethyl)-Acetamide, N-[(2E)-3-phenyl-2-buteny1]-N-(1,1-dimethylethyl)-0 _________________________________________________ Acetamide, N-[(2E)-3-pheny1-2-butenyll-N-etheny1)-N

Compound # Structure (Novel compounds) CA Index Name 297 Acetamide, N-[(2E)-3-phenyl-2-N) butenyll-N-(2-propeny1)-Acetamide, N-{(2E)-3-phenyl-2-butenyl]-N-(cycloprcpylmethyl)-299 11) 0 ________ Acetamide, N-[(2E)-3-phenyl-2-lit L., 300 butenyli-N-butyl-Acetamide, N-[(2E)-3-phenyl-2-butenyl]-N-(2-methylpropy1)-Acetamide, N-[(2Z)-3-pheny1-2-butenyil-N-methyl-NA, 302 ______________________________________________________ 410 Acetamide, N-[(2Z)-3-pheny1-2-buteny1]-N-ethyl-N

Acetamide, N-[(2Z)-3-phenyl-2-butenyl]-N-propyl-N
L) _______________________________________________________________________________ ____________ 410 Acetamide, N-[(2Z)-3-pheny1-2-butenyl]-N-(1-methylethyl)-NJt, _305 Acetamide, N-[(2Z)-3-pheny1-2-410 butenyl]-N-(1,1-dimethylethyl)-Acetamide, N-[(2Z)-3-pheny1-2-butenyl]-N-etheny1)-"L=

Compound # Structure (Novel compounds) CA Index Name Acetamide, N-[(2Z) -3 -phenyl -2-butenyl] -N -(2 -propenyl) -NA, 308 ____________ 410 ________________________________________________ Acetamide, N -[(2Z) -3 -phenyl -2-butenyll-N-(cyclopropylmethyl)-N

110 _______________________________________________ Acetamide, N-[(2Z)-3-pheny1-2-buteny1]-N -butyl -N

Acetamide, N-[(2Z)-3-pheny1-2-butenyl) -N -(2 -methylpropyl) -NA, 311 Acetamide, N-methyl-N-[(2Z,6Z)-2-methyl-2,6-nonadieny1]-N Acetamide, N -ethyl-N-[(2Z,6Z)-2-¨ m ¨(¨N 7 ethy1-2,6-nonadienyll---%=/--/¨\
313 Acetamide, N-[(2Z,6Z)-2-methy1-2,6-/¨j nonadieny1]-N-propyl--m\--314 Acetamide, N -(1 -methylethyl)-N-[(2Z,62) -2 -methyl -2,6 -nonadienyl] -N
Acetamide, N -(1,1 -dimethylethyl) -N -[(2Z,6Z)-2-methy1-2,6-nonadieny1]---v_ N Acetamide, N -ethenyl -N -[(2Z,6Z)-2 -¨ methy1-2,6-nonadieny1]-317 Acetamide, N -[(2Z,6Z) -2 -methyl -2,6-nonadieny1]-N-(2-propeny1)--N-_ Compound # Structure (Novel compounds) CA Index Name Acetamide, N-(cyclopropylmethyl)-N-[(2Z,6Z)-2-methy1-2,6-nonadieny1]-Acetamide, 319 N-butyl-N-[(2Z,6Z)-methyl-2,6-nonadieny1]-Acetamide, N-[(2Z,6Z)-2-methyl-2,6-nonadieny1]-N-(2-methylpropy1)-321 Cyclopropylcarboxamide, N-methyl-N-[(2E,6Z)-2-methy1-2,6-nonadienyl]-Cyclopropylcarboxamide, N-ethyl-N-[(2E,6Z)-2-methy1-2,6-nonadieny1]-323 Cyclopropylcarboxamide, N-[(2E,6Z)--, 2-methy1-2,6-nonadieny1]-N-propyl-N)TIrr ¨324 Cyclopropylcarboxamide, N-(1-methylethyl)-N-[(2E,6Z)-2-methyl-2,6-nonadienyl]-325 Cyclopropylcarboxamide, N-(1,1-dimethylethyl)-N-[(2E,6Z)-2-methyl-2,6-nonadieny1]-326 Cyclopropylcarboxamide, N-ethenyi-N-[(2E,6Z)-2-methy1-2,6-nonadienyl]-L, 327 Cyclopropylcarboxamide, N-[(2E,6Z)-2-methy1-2,6-nonadienyl] -N-(2-N)LT7 propeny1)-328 Cyclopropylcarboxamide, N-(cyclopropylmethyl)-N-[(2E,6Z)-2-methyl-2,6-nonadieny1]-329 Cyclopropylcarboxamide, N-butyl-N-[(2E,6Z)-2-methy1-2,6-nonadieny1]-N) i Compound # Structure (Novel compounds) CA Index Name 330 \ o Cyclopropylcarboxamide, N-[(2E,6Z)-2-methy1-2,6-nonadieny1]-N-(2--'7Ths1).'i / methylpropy1)-o Propanamide, N-methyl-N-[(2E)-3-(3-li cyclohexen-1-y1)-2-propenyll-i _______________________________________________________________________________ _________ I

W Propanamide, N-ethyl-N-[(2E)-3-(3-J\.7- cyclohexen-1-y1)-2-propenylj-/
I
¨333c Propanamide, N-[(2E)-3-(3-cyclohexen-1-y1)-2-propenyli-N-ProPY1-, 34 )3 Q Propanamide, N-(1-methylethyl)-N-[(2E)-3-(3-cyclohexen-l-y1)-2-,---,,,,---.
1 fs,1 1 , propeny1]-o Propanamide, N-(1,1-dimethylethyl)-11)(õ,- N-[(2E)-3-(3-cyclohexen-l-y1)-2-L) .1\ propeny1]-I
o Propanamide, N-ethenyl-N-[(2E)-3-il i (...,..)--..õ.õ- (3-cyclohexen-1-y1)-2-propenyll-, 1 I
o 337 Propanamide, N-[(2E)-3-(3-I 1 cyclohexen-1-y1)-2-propeny1)-N-(2-propeny1)-I

q Propanamide, N-(cyclopropyimethyl)-N-[(2E)-3-(3-cyclohexen-1-y1)-2-propenyli-o Propanamide, N-butyl-N-[(2E)-3-(3-40 - 1,1H cyclohexen-1-y1)-2-propenyll-K, Propanamide, N-[(2E)-3-(3-40 , NAõõ cyclohexen-1-y1)-2-propeny1]-N-(2-methylpropy1)-I
-- Propanamide, N-methyl-N-[(2Z)-3-(3-Ili o cyclohexen-1-y1)-2-propenyl3-I

, , Compound # Structure (Novel compounds) CA Index Name i Propanamide, N-ethy1-N-[(2Z)-3-(3-"--I 1 cyclohexen-1-y1)-2-propenyll-!
343 ,'.-, . Propanamide, N-[(2Z)-3-(3-1 cyclohexen-l-y1)-2-propeny1)-N-c ! propyl-\J
, _________________________________________________ 344 v.-, Propanamide, N-(1-methylethyl)-N-, [(2Z)-3-(3-cyclohexen-1-y1)-2-propenyll-N)õv 84 Ir'''' Propanamide, N-(1,1-dimethy1ethyl)-y) c N-[(22)-3-(3-cyclohexen-1-y1)-2-N),. propeny1]-I

IP c __________ Propanamide, N-ethenyl-N-[(2Z)-3-(3-cyclohexen-1-y1)-2-propeny1]-N
1 L, 347 i r'-i Propanamide, N-[(2Z)-3-(3-) c 1 cyclohexen-i-v1) -2-propenyl] -N- (2-. propenyl) -I
I
1Propanamide, N-(cyclopropylmethyl)-346 , ('-'=1 N-[(2Z)-3-(3-cyclohexen-l-y1)-2-propenv1]-i =
, y , _ _________________________________________________ 349 _______________ 410 o Propanamide, N-butyl-N-[(2Z)-3-(3-cyclohexen-l-y1)-2-propenyll-350 r-"' Propanamide, N-[(2Z)-3-(3-o cyclohexen-1-y1)-2-propeny1]-N-(2-methylpropy1)-i , I
Compound # Structure (Novel compounds) CA Index Name o 351 Acetamide, N-methyl-N-[(2E)-3-(3-1 i.I.
r'-Nr.- cyclohexen-i-v1)-2-propenyll-1 i 1 i 1 !
.
!
352 u o Acetamide, N-ethyl-N-[(2E)-3-(3-Icyclohexen-1-y1)-2-propeny1)-i ( I
!
I
Acetamide, N-[(2E)-3-(3-cyclohexen-9 1-y1)-2-propeny1)-N-propyl-I
o Acetamide, N-(1-methylethv1)-N-I (:) [(2E)-3-(3-cyclohexen-l-y1)-2-propenyl]-i _______________________________________________________________________________ _______ o 1 Acetamide, N-(1,1-dimethylethyl)-N-[ ( 2E -.3.- (3-cyclohexen-i-vi) -2-1..;...) i propenyll -.----o Acetamide, N-etheny1-N-[(2E)-3-(3-356 cyclohexen-1-y1)-2-propeny1)-, ? i Acetamide, N-[(2E)-3-(3-cyclohexen-i !
1-y1)-2-propenv11-N-(2-propeny1)-I , . __________________ I
358 o Acetamide, N-(cyclopropyimethyl)-N- i (---,--------N-1-L- [(2E)-3-(3-cyclohexen-1-v1)-2-i propeny1)-V .

I c P
lAcetamide, N-butyl-N-[(2E)-- (3-i cycichexen-1-y1) -2-propenyll -I

o Acetamide, N-[(2E)-3-(3-cyclohexen-_______________________________________________________________________________ _________ 410 N)L' 1-y1)-2-propeny1)-N-(2----_______________________________________________________________________________ ______ methylpropy1)-_______________________________________________________________________________ _________ _ -- ,,,, Acetamide, N-methyl-N-[(2Z)-3-(3-I cyc1ohexen-1-y1)-2-propeny1)-*--....7"
I
_______________________________________________________________________________ ________ _ - __________________________________________________ Acetamide, N-ethyl-N-[(2Z)-3-(3-o cyclohexen-1-y1)-2-propeny1)-L, _______________________________________________________________________________ _______ Compound # Structure (Novel compounds) CA Index Name 1 Acetamide, N-[(2Z)-3-(3-cyclohexen-1 , 1-y1)-2-propeny1]-N-propyl-\

364 :
'',. AcetamiCe, N-(1-methylethyl)-N-i [(2Z)-3-(3-cyclohexen-1-y1)-2-o propeny1]-NõLL

÷
Acetamide, N-(1,1-dimethylethyl)-N---,,:.
[(2Z)-3-(3-cyclohexen-1-y1)-2-, o 1-- it propenv11-"-õz,õ---,v--,T\

AcetamiCe, N-ethenyl-N-[(2Z)-3-(3-, (,) cvciohexen-1-y1)-2-propenyll-IL---,õ

010 o Acetamide, N-[(2Z)-3-(3-cyciohexen-1-y1)-2-propeny1]-N-(2-propeny1)-i , , _______________________________________________________________________________ _______ 1 Acetamide, N-(cyclopropylmethyl)-N-r) 0 [(2Z)-3-(3-cyclohexen-1-y1)-2-propenyll-ri V:
I Acetamide, N-butyl-N-[(2Z)-3-(3-369 1 I .cyclohexen-l-y1)-2-propenyl]-N
\ ---- \ ---010 o Acetamide, N-[(2Z)-3-(3-cyclohexen-l-y1)-2-propeny1]-N-(2-methylpropy1)-Propanamide, N-methyl-N-[(2E)-3-(3-410 '' NK
cyclohexen-1-y1)-2-propeny1]-2,2-I
dimethyl-i Compound # Structure (Novel compounds) CA Index Name 372 Propanamide, N-ethyl-N-[(2E)-3-(3-7-7( cyclohexen-1-y1)-2-propeny1]-2,2-;.,v dimethyl-373 Propanamide, N-[(2E)-3-(3-! cyclohexen-1-y1)-2-propeny11-N-i I
propy1-2,2-dimethyl-/
374 Propanamide, N-(1-methylethyl)-N-NIK [(2E)-3-(3-cyclohexen-1-y1)-2-I
propeny11-2,2-dimethyl-___________________ -i Q Propanamide, N-(1,1-dimethylethyl)-' N-[(2E)-3-(3-cyc1ohexen-l-y1)-2-, 1 propeny11-2,2-dimethyl-i 376 i . _____________________________ c Propanamide, N-ethenyl-N-[(2E)-3-J1,,Nr( (3-cyc1ohexen-l-y1)-2-propenv11-I I 7 2,2-dimethyl-;õi '., =
c Propanamide,-N-[(2E)-3-(3 JINK
cyclohexen-1-y1)-2-propeny1]-N-(2-, propeny1)-2,2-dimethy1-=:,-,..õ.- '-;,,J
. c Propanamide, N-(cyclopropylmethyl)-I N N-H2E)-3-(3-cyclohexen-1-y1)-2-1 , propeny11-2,2-dimethyl-I
, t 0 Propanamide, N-butyl-N-[(2E)-3-(3-.11, T( cyclohexen-l-y1)-2-propeny11-2,2-I
dimethyl-1 (- , 380 i ______________________________ Propanamide, N-[(2E)-3-(3-, -. ,,c, cyclohexen-l-y1)-2-propenyll-N-(2-0 methylpropy1)-2,2-dimethyl-381 0 --c-- Propanamide, N-methyl-N-[(2Z)-3-(3-N , cyclohexen-1-y1)-2-propeny1]-2,2-I dimethyl-_______________________________________________________________________________ __________ _ Propanamide, N-ethyl-N-[(2E)-3-(3-N
382 0 ,Yc< cyclohexen-l-y1)-2-propeny11-2,2-\ dimethyl-/
_______________________________________________________________________________ __________ _.
383 Propanamide, N-[(2Z)-3-(3-cyclohexen-1-y1)-2-propeny1]-N-N
.-- -.. propy1-2,2-dimethyl-, Compound # Structure (Novel compounds) ICA Index Name M 9 Propanamide, N-(1-methylethyl)-N-[(2Z)-3-(3-cyclohexen-1-y1)-2-NI)* propenyl ] -2, 2-dimethyl-1 /\
1 385 i--------,--- c iPropanamide, N-(1,1-dimethylethyl)-i 1 ,N IN-[(2Z)-3-(3-cyclohexen-1-y1)-2-i Ipropenyli-2,2-dimethyl-_______________________________________________________________________________ _________ I
386 r-,,,,õ a Propanamide, N-ethenyl-N-[(2Z)-3-(3-cyclohexen-1-y1)-2-propenyli-1 1 2,2-dimethyl-I-,..-----' i 387 ,---r--Th- 0 i 1 1 Propanamide, N-[(2Z)-3-(3-! -....,......d N1,4},....< cyclohexen-l-y1)-2-propenyl]-N-(2-propeny1)-2,2-dimethyl-, I _________________________________________________ i __________________ 1 388 1 (""('''--1 0 Propanamide, N-(cyclopropylmethyl)- I
N
'k,) !<- N-[(2Z)-3-(3-cyc1ohexen-l-y1)-2-Ipropeny1]-2,2-dimethyl-1 , i _______________________________________________________________________________ ________ (Cr o Propanamide, N-butyl-N-P2Z)-3-(3-i cyclohexen-1-y1)-2-propeny1]-2,2-i N
!
/ dimethyl-II

Propanamide, N-[(22)-3-(3-- o I , , ij .
i cyclohexen-l-y1)-2-propenyll-N-(2-N'Th<
i I 1 methyipropyl) -2, 2-dimethvi-I
, _______________________________________________________________________________ ________ I 391 1 I Qh Butanamide, N-methyl-N-[(2E)-3,7-I
dimethy1-2,6-octadieny1]-2-methyl-_,0,4. i I
I
, I - I F, Butanamide, N-ethyl-N-[(2E)-3,-i-1 _) I

'dimethy1-2,6-octadienv1]-2-methyl-I
I .---o Butanamide, N-[(2E)-3,7-dimethyl-2,6-octadieny1]-N-propy1-2-methyl----/ .-' -394 o Butanamide, N-(1-methylethyl)-N-,N-[(2E)-3,7-dimethy1-2,6-octadieny1]-¨7/ 2-methyl-o Butanamide, N-(1,1-dimethylethyl)-IL./ N-[(2E)-3,7-dimethy1-2,6-// --' octadieny1]-2-methyl-Compound # Structure (Navel compounds) CA Index Name Butanamide, N-ethenyl-N-[(2E)-3,7--. dimethy1-2, 6-octadienyl]
-2-methyl-N
/
_ 397 I o Butanamide, N-[(2E)-3,7-dimethyl--, 2,6-octadieny1]-N-(2-propeny1)-2-methyl--------,_----J ----o Butanamide, N-(cyclopropylmethyl)-N-[(2E)-3,7-dimethy1-2,6-V) octadieny1]-2-methyl-399 1 1 o Butanamide, N-butyl-N-[(2E)-3,7--, dimethy1-2,6-octadieny1]-2-methyl-If ' 400 1 o Butanamide, N-[(2E)-3,7-dimethyl-2,6-octadienyl]-N-(2-methylpropy1)-2-methyl-401 Butanamide, N-methyl-N-[(2Z)-3,7-0 dimethy1-2,6-octadieny1]-2-methyl-i 402 Butanamide, N-ethyl-N-[(2Z)-3,7-0 dimethy1-2,6-octadieny1]-2-methyl-isl'ILT:
___________________ _ _____________________________ 403 Butanamide, N-[(2Z)-3,7-dimethyl-1Ly,- 2,6-octadieny1]-N-propy1-2-methyl-N
/
_______________________________________________________________________________ _______ _ 404 Butanamide, N-(1-methylethyl)-N-o [(2Z)-3,7-dimethy1-2,6-octadieny1]-2-methyl-405 Butanamide, N-(1,1-dimethylethyl)-,"., 0 N-[(2Z)-3,7-dimethy1-2,6-octadieny1]-2-methyl-___________________ _ _____________________________ 406 Butanamide, N-ethenyl-N-[(2Z)-3,7-1)1 dimethy1-2,6-octadieny1]-2-methyl----3:.õ

Compound # Structure (Novel compounds) CA Index Name 407 Butanamide, N-[(2Z)-3,7-dimethyl-0 2,6-octadieny1]-N-(2-propeny1)-2-\N methyl-408 Butanamide, N-(cyclopropylmethyl)--, \ 0 N-[(2Z)-3,7-dimethy1-2,6-N octadieny1]-2-methyl-409 Butanamide, N-butyl-N-[(2Z)-3,7-o dimethy1-2,6-octadieny1]-2-methyl-410 Butanamide, N-[(2Z)-3,7-dimethyl-o 2,6-octadieny1]-N-(2-methylpropy1)-\N 2-methyl-411 Cyclopropanecarboxamide, N-methyl-I V

Cyclopropanecarboxamide, N-ethyl-N-N)H7 [(2E)-3,7-dimethy1-2,6-octadieny1]-413 Cyclopropanecarboxamide, N-[(2E)-y 3,7-dimethy1-2,6-octadieny1]-N-propyl-414 Cyclopropanecarboxamide, N-(1-methylethyl)-N-[(2E)-3,7-dimethyl-2,6-octadieny1)-415 Cyclopropanecarboxamide, N-(1,1-')Y dimethylethyl)-N-[(2E)-3,7-dimethy1-2,6-octadieny1]-416 Cyclopropanecarboxamide, N )L17 N-[(2E)-3,7-dimethy1-2,6-octadieny1]-417 Cyclopropanecarboxamide, N-[(2E)-3,7-dimethy1-2,6-octadieny1]-N-2-propenyl-418 Cyclopropanecarboxamide, N-N)LTer (cyclopropylmethyl) -N-[(2E)-3,7-v) dimethy1-2,6-octadieny1]-Compound # Structure (Novel compounds) CA Index Name 419 Cyclopropanecarboxamide, N-butyl-N-)LT/ [(2E)-3,7-dimethy1-2,6-octadienyll-rrN
o Cyclopropanecarboxamide, N -[(2E)-)1v 3,7-dimethy1-2,6-octadieny1]-N-(2-N
methylpropyl) -421 Cyclopropanecarboxamide, N-methyl-..--N7 0 N -[(2Z)-3,7 -dimethyl -2,6 -NN)L1/' octadieny1]-I
422 Cyclopropanecarboxamide, N-ethyl-N-.--,,,, 0 [(2Z) -3,7 -dimethyl -2,6 -octadieny1]-NN)LT/
423 Cyclopropanecarboxamide, N-[(2Z)-.,:,----- 3,7-dimethy1-2,6-octadieny1]-N-\N1,7, propyl-424 Cyclopropanecarboxamide, N-(1-methylethyl) -N -[(2Z) -3,7-dimethyl-NN AT/ 2,6-octadieny1]-/1\
425 Cyclopropanecarboxamide, N -(1,1-,,,,--= 0 dimethylethyl)-N-[(2Z)-3,7-N AT/ dimethy1-2,6-octadieny1]-N
426 Cyclopropanecarboxamide, N-ethenyl----.. 0 N-[(2Z)-3,7-dimethy1-2,6-nlY octadieny1]--;,----J
. 427 Cyclopropanecarboxamide, N-[(2Z)-."../ 0 3,7-dimethyl -2,6 -octadieny1]-N-2 -NN)T7 propeny1 -428 Cyclopropanecarboxamide, N-....--.,--.,õ 0 (cyclopropylmethyl) -N-[(2Z)-3,7-NNAv dimethy1-2,6-octadienyl]-T) 429 Cyclopropanecarboxamide, N -butyl-N-[(2Z)-3,7-dimethy1-2,6-octadieny1]-N ,ILT7 N
----/----/

Compound # Structure (Novel compounds) CA Index Name 430 Cyclopropanecarboxamide, 0 3,7-dimethy1-2,6-octadieny11-N-(2-methylpropy1)-Propanamide, N-methyl-N-[(2E)-3,7-dimethy1-2,6-octadieny1]-2-methyl-Propanamide, N-ethyl-N-[(2E)-3,7-dimethy1-2,6-octadieny1]-2-methyl-433 Propanamide, N-[(2E)-3,7-dimethyl-N
2,6-octadieny1]-N-propy1-2-methyl---r Propanamide, N-(1-methylethyl)-N-[(2E)-3,7-dimethy1-2,6-octadieny1]-2-methyl-0 _________________________________________________ Propanamide, N-(1,1-dimethylethyl)-N-[(2E)-3,7-dimethy1-2,6-octadieny1]-2-methyl-436 Propanamide, N-ethenyl-N-[(2E)-3,7-N, N dimethy1-2,6-octadieny1]-2-methyl-437 Propanamide, N-[(2E)-3,7-dimethyl-2,6-octadieny1]-N-(2-propeny1)-2-methyl-Propanamide, N-(cyclopropylmethyl)-N-[(2E)-3,7-dimethy1-2,6-octadieny1]-2-methyl-439 Propanamide, N-butyl-N-[(2E)-3,7-dimethy1-2,6-octadieny1]-2-methyl-Propanamide, N-[(2E)-3,7-dimethyl-2,6-octadieny1]-N-(2-methylpropy1)-2-methyl-441 Propanamide, N-methyl-N-[(2Z)-3,7-o dimethy1-2,6-octadieny1]-2-methyl-Compound # Structure (Novel compounds) CA Index Name Propanamide, N -ethyl -N -[(2Z) -3,7 --0 dimethy1-2,6-octadieny1]-2 -methyl-Propanamide, N-[(2Z)-3,7 -dimethyl-0 2,6-octadienyl] -N-propyl -2 -methyl -N

-444 Propanamide, N -(1 -methylethyl) -N-0 [(2Z)-3,7-dimethy1-2,6-octadieny1]--,N 2-methyl-445 Propanamide, N-(1,1-dimethylethyl)-/. N -[(2Z) -3,7 -dimethyl -2,6 -octadieny1]-2-methyl-Propanamide, N -ethenyl-N-[(2Z)-3,7-o dimethy1-2,6-octadieny1]-2-methyl-Propanamide, N-[(2Z)-3,7-dimethyl-0 2,6 -octadieny1]-N-(2 -propeny1)-2-N methyl-o Propanamide, N-(cyclopropylmethyl)-N-[(2Z)-3,7-dimethyl -2,6-N octadienyl] -2 -methyl --449 Propanamide, 0 dimethyl -2,6 -octadieny11-2 -methyl-Propanamide, N-[(2Z)-3,7-dimethyl-0 2,6 -octadienyl] -N -(2 -methylpropyl) -2-methyl-451 0 2 -butenamide, N -methyl -N -[(2E) -3,7 -dimethyl -2,6 -octadienyl] -, (2E)-2 -butenamide, N -ethyl -N -[(2E) -3,7 -dimethy1-2,6-octadienyl3-, (2E)-Compound # Structure (Novel compounds) CA Index Name 2-butenamide, N-[(2E) -3,7 -dimethyl-2,6-octadienyl]-N-propyl-, (2E)--454 0 2-butenamide, N-(1-methy1ethyl)-N-N [(2E)-3,7-dimethy1-2,6 -octadienyl] -, (2E)-2-butenamide, N-(1,1-dimethylethyl)-N-P2E)-3,7-// dimethy1-2,6-octadieny1]-, (2E)-456 2-butenamide, N-ethenyl-N-[(2E)-3,7-dimethy1-2,6-octadieny1]-, (2E)-_ o 2-butenamide, N-[(2E)-3,7-dimethyl-2,6-octadieny1J-N-(2-propeny1)-, (2E)-o 2-butenamide, N-(cyclopropylmethyl)-N-[(2E)-3,7-dimethy1-2,6-octadieny1]-, (2E)-o 2-butenamide, N-butyl-N-[(2E)-3,7-dimethy1-2,6-octadieny1]-, (2E)-r-f-j 2-butenamide, N-[(2E)-3,7-dimethyl-2,6-octadienyli-N-(2-methylpropy1)-, (2E)-461 2-butenamide, N-methyl-N-[(2Z)-3,7-9 dimethy1-2,6-octadieny1]-, (2E)-o 2 -butenamide, N-ethyl-N-[(2Z)-3,7-dimethy1-2,6-octadieny1]-, (2E)-463 2-butenamide, N-[(2Z)-3,7-dimethyl-0 2,6-octadieny1]-N-propyl-, (2E)-464 2-butenamide, N-(1-methylethyl)-N-o [(2Z)-3,7-dimethy1-2,6-octadieny1]-, (2E)-Compound # Structure (Novel compounds) CA Index Name 465 1 2-butenamide, N-(1,1-dimethylethyl)-N-[(2Z)-3,7-dimethy1-2,6-octadieny1]-, (2E)-2-butenamide, N-ethenyl-N-[(2Z)-3,7-dimethy1-2,6-octadieny1]-, (2E)-467 2-butenamide, N-[(2Z)-3,7-dimethyl-o 2,6-octadienyl]-N-(2-propeny1)-, (2E)-468 2-butenamide, (cyclopropylmethyl)-N-[(2Z)-3,7-dimethy1-2,6-cctadieny1]-, (2E)-469 2-butenamide, N-butyl-N-[(2Z)-3,7-0 dimethy1-2,6-octadieny1]-, (2E)-470 2-butenamide, N-[(2Z)-3,7-dimethyl-o 2,6-octadienyl]-N-(2-methylpropy1)-, (2E)-471 ? 2-butenamide, N-methyl-N-[(2E)-3,7-dimethy1-2,6-octadieny1]-3-methyl-472 2-butenamide, N-ethyl-N-[(2E)-3,7-dimethy1-2,6-octadienyl]-3-methyl-473 2-butenamide, N-[(2E)-3,7-dimethy1-2,6-octadieny1]-N-propy1-3-methyl-474 9 / 2-butenamide, N-(1-methylethyl)-N-ww- [(2E)-3,7-dimethy1-2,6-octadieny1]-3-methyl--475 2-butenamide, N-(1,1-N dimethylethyl)-N-[(2E)-3,7-dimethy1-2,6-octadieny1]-3-methyl-476 2-butenamide, N-ethenyl-N-[(2E)-Nj 3,7-dimethy1-2,6-octadieny1]-3-methyl-Compound # Structure (Novel compounds) GA Index Name 0 2-butenamide, N-[(2E)-3,7-dimethyl-2,6-octadienyl]-N-(2-propeny1)-3-methyl-478 / 2-butenamide, (cyclopropylmethyl)-N-[(2E)-3,7-dimethy1-2,6-octadieny1]-3-methyl-479 9 / 2-butenamide, N-butyl-N-[(2E)-3,7-r-N dimethy1-2,6-octadieny1]-3-methyl-I

2-butenamide, N-[(2E)-3,7-dimethyl-2,6-octadieny1]-N-(2-methylpropy1)-3-methyl-2-butenamide, N-methyl-N-[(2Z)-3,7-/ dimethy1-2,6-octadieny1]-3-methyl-482 2-butenamide, N-ethyl-N-[(2Z)-3,7-9 / dimethy1-2,6-octadieny1]-3-methyl-483 2-butenamide, N-[(2Z)-3,7-dimethyl-/ 2,6-octadienyl]-N-propy1-3-methyl-(N
2-butenamide, N-(1-methylethyl)-N-.
/ [(2Z)-3,7-dimethy1-2,6-octadieny1]-3-methyl-2-butenamide, N-(1,1-7L7 9 / dimethylethyl)-N-[(2Z)-3,7-dimethy1-2,6-octadieny1]-3-methyl-486 2-butenamide, N-ethenyl-N-[(2Z)-/ 3,7-dimethy1-2,6-octadieny1]-3-methyl-2-butenamide, N-[(2Z)-3,7-dimethyl-/ 2,6-octadieny1]-N-(2-propeny1)-3-methyl-, Compound # Structure (Novel compounds) CA Index Name _______________________________________________________________________________ _________ _ _ _________________________________________________ 488 2-butenamide, N-''''''= o , (cyc1opropy1methy1)-N-[(2Z)-3,7-dimethy1-2,6-octadieny1]-3-methyl-T-) 4 8 9 2-butenamide, N-butyl-N-[(2Z)-3,7-9 i dimethy1-2,6-octadieny1]-3-methyl-___/----/
, N-[( )-3, meth 490 2-butenamide 2Z
7-di 1-7-Y
-.j/..-.
9 / 2,6-3,7 -N-(2-methylpropy1)-NNA.õ...>". 3-methyl-491 ..--------o Cyclopropanecarboxamide, N-_______________________________________________________________________________ _________ ___ [(2E,6Z)-2,6-dodecadieny1]-N-N)Y methyl-492 ...----,-----,. o Cyclopropanecarboxamide, N-[(2E,6Z)-2,6-dodecadieny1]-N-ethyl-/) 493 .-------------.
o Cyclopropanecarboxamide, N-[(2E,6Z)-2,6-dodecadieny1]-N-(N)Y propyl-/) 4 9 4 ------------- 0 Cyclopropanecarboxamide, N-(1-methylethyl )-N-[(2E,6Z)-2,6-N)Y dodecadienyl]-/K
r"--495 --- o Cyclopropanecarboxamide, N-(1,1-dimethylethyl)-N-[(2E,6Z)-2,6-7-WN'IY dodecadienyl]--4\
_ __________________ 496 ----\., 0 Cyclopropanecarboxamide, N-ethenyl-N-H2E,6Z)-2,6-dodecadienyl]-il i*) --------_ 497 .v---," . o Cyclopropanecarboxamide, N-_______________________________________________________________________________ __________ _ [(2E,6Z)-2,6-dodecadieny1]-N-(2-N)Y propeny1)-'"...) 498 7'\,--"\ 0 Cyclopropanecarboxamide, N-(cyclopropylmethyl)-N-2E,6Z)-2,6-Thµr)C17 dodecadieny1]-P
V) Compound # Structure (Novel compounds) CA Index Name 499 Cyclopropanecarboxamide, N-butyl-N-[(2E,6Z)-2,6-dodecadieny1]-500 Cyclopropanecarboxamide, N-[(2E,6Z)-2,6-dodecadienyl]-N-(2-WN )H7 methylpropy1)-501 Cyclopropanecarboxamide, N-[(2Z,6Z)-2,6-dodecadienyll-N-0 methyl-502 Cyclopropanecarboxamide, N-[(2Z,6Z)-2,6-dodecadieny1]-N-ethyl-/) 503 Cyclopropanecarboxamide, N-[(2Z,6Z)-2,6-dodecadienyll-N-0 propy 1-504 Cyclopropanecarboxamide, N-(1-methylethyl 0 dodecadieny1]-N
../1\
505 Cyclopropanecarboxamide, N-(1,1-dimethylethyl)-N-[(2Z,6Z)-2,6-dodecadieny1]-506 Cyclopropanecarboxamide, N-ethenyl-N-[(2Z,6Z)-2,6-dodecadieny1]-7\ 0 N
,) ;
Compound # Structure (Novel compounds) CA Index Name 507 .,.'\./\ Cyclopropanecarboxamide, N-[(2Z,62)-2,6-dodecadieny1]-N-(2-0 propeny1)-508 /\../\ Cyclopropanecarboxamide, N-(cyclopropylmethyl)-N-[(2Z,6Z)-2,6-0 dodecadieny1]-N.1,1 =
509 /\./\ Cyclopropanecarboxamide, N-butyl-N-[(2Z,6Z)-2,6-dodecadienyl]-N
/
/
510 /\/''. Cyclopropanecarboxamide, N-[(2Z,6Z)-2,6-dodecadieny1]-N-(2-0 methylpropy1)-INI,i,1 ...7) III till'V Cyclopropanecarboxamide, N-[(2E)-3-(4-methyl-3-cyclohexen-1-y1)-2-buteny1]-N-methyl-o r . ___________________________ 0 ) o 512 Cyclopropanecarboxamide, N-[(2E)-3-si __________________________________________________ (4-methyl-3-cyclohexen-l-y1)-2-buteny1]-N-ethyl-513 Cyclopropanecarboxamide, N-[(2E)-3-40 rij,I)L17 (4-methy1-3-cyclohexen-l-y1)-2-butenyli-N-propy1-o 514 Cyclopropanecarboxamide, N-[(2E)-3-410 :21\1-kr (4-methy1-3-cyclohexen-l-y1)-2-buteny1]-N-(1-methylethyl)-______________________________________ o 515 Cyclopropanecarboxamide, N-[(2E)-3-¨7Nlt/1 (4-methy1-3-cyclohexen-1-y1)-2-butenyli-N-(1,1-dimethylethyl)-_______________________________________________________________________________ _________ _ o 516 Cyclopropanecarboxamide, N-[(2E)-3-(4-methy1-3-cyclohexen-1-y1)-2-butenyli-N-ethenyl-Compound # Structure (Navel compounds) GA Index Name Cyclopropanecarboxamide, N-[(2E)-3-(4-methy1-3-cyclohexen-l-y1)-2-buteny1]-N-(2-propeny1)-Cyclopropanecarboxamide, N-[(2E)-3-(4-methy1-3-cyclohexen-1-y1)-2-buteny1]-N-(cyclopropylmethyl)-0 Cyclopropanecarboxamide, N-[(2E)-3-III1/17 (4-methy1-3-cyclohexen-1-y1)-2-buteny1]-N-butyl-Cyclopropanecarboxamide, N-[(2E)-3-(4-methy1-3-cyclohexen-1-y1)-2-butenyll-N-(2-methylpropy1)-521 Cyclopropanecarboxamide, N-[(2Z)-3-410 (4-methy1-3-cyclohexen-1-y1)-2-butenyll-N-methyl-NJ.LI7 522 Cyclopropanecarboxamide, N-[(2Z)-3-010 (4-methy1-3-cyclohexen-4-y1)-2-buteny1]-N-ethyl-523 Cyclopropanecarboxamide, N-[
(2Z)-3-110 (4-methy1-3-cyclohexen-1-y1)-2-buteny1]-N-propyl-N)y, ¨524 Cyclopropanecarboxamide, N-[
(2Z)-3-110 (4-methy1-3-cyclohexen-1-y1)-2-buteny1]-N-(1-methylethyl)-N_Ay /k 525 Cyclopropanecarboxamide, N-[(2Z)-3-(4-methy1-3-cyclohexen-1-y1)-2-butenyli-N-(1,1-dimethylethyl)-N

Compound # Structure (Novel compounds) CA Index Name Cyclopropanecarboxamide, N-[(2Z)-3-(4-methy1-3-cyclohexen-1-y1)-2-buteny1]-N-ethenyl-527 Cyclopropanecarboxamide, N-[
(2Z)-3-.
010 (4-methy1-3-cyclohexen-1-y1)-2-butenyll-N-(2-propeny1)-N)Y
528 Cyclopropanecarboxamide, N-[(2Z)-3-110 (4-methy1-3-cyclohexen-1-y1)-2-butenyli-N-(cyclopropylmethyl)-N
\1,-) 529 Cyclopropanecarboxamide, ________ 110 (4-methy1-3-cyclohexen-1-y1)-2-butenyll-N-butyl-N
530 Cyclopropanecarboxamide, N-[(2Z)-3-410(4-methy1-3-cyclohexen-1-y1)-2-buteny1]-N-(2-methylpropy1)-N
>') Cyclopropanecarboxamide, N-(3-methy1-2-buteny1)-N-methyl-Cyclopropanecarboxamide, N-(3-methy1-2-buteny1)-N-ethyl-Cyclopropanecarboxamide, N-(3-methy1-2-buteny1)-N-propyl-534 Cyclopropanecarboxamide, N-(3-methy1-2-buteny1)-N-(1-methylethyl)-Cyclopropanecarboxamide, N-(3-methyl-2-buteny1)-N-(1,1-dimethylethyl)-Compound # Structure (Novel compounds) CA Index Name o 536 Cyclopropanecarboxamide, N-(3-)1'1 methy1-2-buteny1)-N-ethenyl-e) ____________________________________ o Cyclopropanecarboxamide, N-(3-methy1-2-buteny1)-N-(2-propeny1)-____________________________________ o Cyclopropanecarboxamide, N-(3---f7 methy1-2-buteny1)-N-V) (cyclopropylmethyl)-o Cyclopropanecarboxamide, N-(3-methy1-2-buteny1)-N-butyl-o Cyclopropanecarboxamide, N-(3--T/
methyl-2-buteny1)-N-(2-* methylpropy1)-00 71T7 _______ Cyclopropanecarboxamide, N-methyl-N-[(2E)-3-(2,4-dimethy1-3-cyclohexen-1-y1)-2-propeny1]-0 N))ci7 Cyclopropanecarboxamide, N-ethyl-N-[(2E)-3-(2,4-dimethy1-3-cyclohexen-1-y1)-2-propeny1]-o Cyclopropanecarboxamide, N-[(2E)-3-11110 '1.).7' (2,4-dimethy1-3-cyclohexen-l-y1)-2-propenyl]-N-propyl-o Cyclopropanecarboxamide, N-(1-le j117 Y----- methylethyl)-N-[(2E)-3-(2,4-dimethy1-3-cyclohexen-1-y1)-2-propeny1]-_ 545o Cyclopropanecarboxamide, N-(1,1-III0 --' tµ41--11 methylethyl)-N-P2E)-3-(2,4-dimethy1-3-cyclohexen-1-y1)-2-propeny1]-_______________________________________________________________________________ _______ _ o Cyclopropanecarboxamide, N-ethenyl-410 N--2'N-[(2E)-3-(2,4-dimethy1-3-.4%i cyclohexen-1-y1)-2-propeny1]-o Cyclopropanecarboxamide, N-[(2E)-3-olp N'ILV (2,4-dimethy1-3-cyclohexen-l-y1)-2-propenyll-N-(2-propeny1)-N'-7 Compound # Structure (Novel compounds) CA Index Name -o Cyclopropanecarboxamide, N-1010 1/7 (cyclopropylmethyl)-N-P2E)-3-(2,4-dimethy1-3-cyclohexen-1-y1)-2-propeny1]-o Cyclopropanecarboxamide, N-butyl-N-,¨.....-õ,..---vk.T7 [(2E)-3-(2,4-dimethy1-3-cyclohexen-1-y1)-2-propeny1]-( o Cyclopropanecarboxamide, N-[(2E)-3-0 y)'-7 (2,4-dimethy1-3-cyclohexen-l-y1)-2-propenyl]-N-(2-methylpropy1)-551 Cyclopropanecarboxamide, N-methyl-110 N-[(2Z)-3-(2,4-dimethy1-3-cyclohexen-l-y1)-2-propeny1]-o I
552 Cyclopropanecarboxamide, N-ethyl-N-110 [(2Z)-3-(2,4-dimethy1-3-cyclohexen-1-y1)-2-propeny1]-CN
o \ )L17 553 Cyclopropanecarboxamide, N-[
(2Z)-3-410 (2,4-dimethy1-3-cyclohexen-1-y1)-2-propeny1]-N-propyl-o N)L'r ) , Cyclopropanecarboxamide, N-(1--%('-= methylethyl)-N-[(2Z)-3-(2,4-dimethy1-3-cyclohexen-1-y1)-2-No 17 propeny1]-555 Cyclopropanecarboxamide, N-(1,1-410 methylethyl)-N-[(2Z)-3-(2,4-dimethy1-3-cyclohexen-1-y1)-2-o propeny1]-y \

556 Cyclopropanecarboxamide, N-ethenyl-010 N-[(2Z)-3-(2,4-dimethy1-3-cyclohexen-l-y1)-2-propeny1]-o \ N)L17 *j Compound # Structure (Novel compounds) CA Index Name 557 Cyclopropanecarboxamide, N-[
(2Z)-3-110 (2,4-dimethy1-3-cyclohexen-1-y1)-2-propenyll-N-(2-propeny1)-o N)y _______________________________________________________________________________ _________ ¨
558 Cyclopropanecarboxamide, N-010o (cyclopropylmethyl)-N-[(2Z)-3-(2,4-dimethy1-3-cyclohexen-l-y1)-2-)L.17 propeny1]-N
559 Cyclopropanecarboxamide, N-butyl-N-110 [(2Z)-3-(2,4-dimethy1-3-cyclohexen-1-y1)-2-propeny1]-L.-NII7-jj 560 Cyclopropanecarboxamide, N-[(2Z)-3-110o (2,4-dimethy1-3-cyclohexen-1-y1)-2-propenyll-N-(2-methylpropy1)-N)1,,T7 ________________________________________ 0 561 Acetamide, N-[(2E)-3-(4-methy1-3-0 tsri I cyclohexen-l-y1)-2-buteny1]-N-methyl-_______________________________________________________________________________ _________ _ ' 562 Acetamide, N-[(2E)-3-(4-methy1-3-NI, cyclohexen-1-y1)-2-buteny1]-N-) ethyl-_______________________________________________________________________________ _________ ____ 563 i o Acetamide, N-[(2E)-3-(4-methy1-3-0ts,) cyclohexen-l-y1)-2-buteny1]-N-rj propyl-_ o 564 Acetamide, N-[(2E)-3-(4-methyl-3-410 ''- WIL cyclohexen-l-y1)-2-buteny1]-N-(1-/j'.- methylethyl)-_______________________________________________________________________________ _________ _ o Acetamide, N-[(2E)-3-(4-methy1-3-0N'IL- cyclohexen-1-y1)-2-buteny1]-N-(1,1-dimethylethyl)-o Acetamide, N-[(2E)-3-(4-methyl-3-0 1,1) cyclohexen-1-y1)-2-buteny1]-N-ethenyl-Compound # Structure (Novel compounds) CA Index Name 567 Acetamide, N-[(2E)-3-(4-methyl-3-N1- cyclohexen-1-y1)-2-buteny1]-N-(2-propeny1)-Acetamide, N-[(2E)-3-(4-methyl-3-cyclohexen-1-y1)-2-buteny1]-N-(cyclopropylmethyl)-569 Acetamide, N-[(2E)-3-(4-methy1-3-410 cyclohexen-1-y1)-2-buteny1]-N-butyl-Acetamide, N-[(2E)-3-(4-methy1-3-cyclohexen-1-y1)-2-butenyll-N-(2-õ,,; methylpropy1)-571 Acetamide, N-[(2Z)-3-(4-methy1-3-110 cyclohexen-1-y1)-2-butenyll-N-methyl-572 Acetamide, N-[(2Z)-3-(4-methyl-3-110 cyclohexen-l-y1)-2-buteny1]-N-ethyl-N

Acetamide, N-[(2Z)-3-(4-methy1-3-cyclohexen-1-y1)-2-buteny1]-N-propyl-W
N2' 574 Acetamide, N-[(2Z)-3-(4-methy1-3-410 cyclohexen-l-y1)-2-buteny1]-N-(1-methylethyl)-N
575 Acetamide, N-[(2Z)-3-(4-methy1-3-cyclohexen-1-y1)-2-buteny1]-N-(1,1-dimethylethyl)-NA, Compound # Structure (Novel compounds) CA Index Name 576 Acetamide, N-[(2Z)-3-(4-methy1-3-cyclohexen-1-y1)-2-buteny1]-N-ethenyl-577 Acetamide, N-[(2Z)-3-(4-methy1-3-410 cyclohexen-1-y1)-2-butenyll-N-(2-propeny1)-578 Acetamide, N-[(2Z)-3-(4-methy1-3-cyclohexen-1-y1)-2-butenylj-N-(cyclopropylmethyl)-N
579 Acetamide, N-[(2Z)-3-(4-methy1-3-110 cyclohexen-1-y1)-2-butenyll-N-butyl-J[t., 580 Acetamide, N-[(2Z)-3-(4-methy1-3-cyclohexen-1-y1)-2-buteny1]-N-(2-methylpropy1)-Acetamide, N-methyl-N-[(2E)-3-(2,4-dimethy1-3-cyclohexen-l-y1)-2-propeny1]-Acetamide, N-ethyl-N-[(2E)-3-(2,4-40 dimethy1-3-cyclohexen-l-y1)-2-propeny1]-Acetamide, N-[(2E)-3-(2,4-dimethyl-40 N)L' 3-cyclohexen-1-y1)-2-propeny1]-N-propyl-Acetamide, N-(1-methylethy1)-N-40 N).L [(2E)-3-(2,4-dimethy1-3-cyclohexen-1-y1)-2-propeny1]-Compound # Structure (Novel compounds) CA Index Name o Acetamide, N-(1,1-dimethylethyl)-N-0 [(2E)-3-(2,4-dimethy1-3-cyclohexen->I 1-y1)-2-propeny1]-o Acetamide, N-ethenyl-N-[(2E)-3-0 (2,4-dimethy1-3-cyclohexen-1-y1)-2--'J propenyll-o Acetamide, N-[(2E)-3-(2,4-dimethyl-N,K, 3-cyclohexen-1-y1)-2-propeny1]-N-5 (2-propeny1)-o Acetamide, N-(cyclopropylmethyl)-N-0 tsrl''= [(2E)-3-(2,4-dimethy1-3-cyclohexen---) 1-y1)-2-propeny1]-o Acetamide, N-butyl-N-[(2E)-3-(2,4-410rI)L dimethy1-3-cyclohexen-1-y1)-2-\---\ propeny1]-o Acetamide, N-[(2E)-3-(2,4-dimethyl-410 N"k- 3-cyclohexen-1-y1)-2-propeny1]-N-),) (2-methylpropy1)-591 i Acetamide, N-methyl-N-[(2Z)-3-(2,4-110 o dimethy1-3-cyclohexen-1-y1)-2-propeny1]-592 I Acetamide, N-ethyl-N-[(2Z)-3-(2,4-110 o dimethy1-3-cyclohexen-1-y1)-2-propeny1]-it N' .,) Acetamide, N-[(2Z)-3-(2,4-dimethyl-110 o 3-cyclohexen-1-y1)-2-propenyll-N-propyl-594 ! Acetamide, N-(1-methylethyl)-N-010 o [(22)-3-(2,4-dimethy1-3-cyclohexen-1-y1)-2-propenyll-Compound # Structure (Novel compounds) CA Index Name 595 Acetamide, N-(1,1-dimethylethyl)-N-Oil [(2Z)-3-(2,4-dimethy1-3-cyclohexen-1-y1)-2-propeny1]-N
596 Acetamide, N-ethenyl-N-[(2Z)-3-(2,4-dimethy1-3-cyclohexen-1-y1)-2-propeny1]-NJk, 597 Acetamide, N-[(2Z)-3-(2,4-dimethyl-411 3-cyclohexen-1-y1)-2-propeny1]-N-(2-propeny1)-NA
598 Acetamide, N-(cyclopropylmethyl)-N-110 [(2Z)-3-(2,4-dimethy1-3-cyclohexen-1-y1)-2-propeny1]-N
599 Acetamide, N-butyl-N-[(2Z)-3-(2,4-011 dimethy1-3-cyclohexen-1-y1)-2-propeny1]-N
600 Acetamide, N-[(2Z)-3-(2,4-dimethyl-3-cyclohexen-1-y1)-2-propeny1]-N-o (2-methylpropy1)-601 / ________ Propanamide, N-methyl-N-(2,6-nonadieny1)-602 , / Propanamide, N-ethyl-N-(2,6-nonadieny1)-603 R, / Propanamide, N-(2,6-nonadieny1)-N-propyl-Compound # Structure (Novel compounds) CA Index Name 604 ___________________________________ 0, / Propanamide, N-(1-methylethyl)-N-(2,6-nonadieny1)-605 (z) Propanamide, N-(1,1-dimethylethyl)-- N-(2,6-nonadieny1)-606 Propanamide, nonadieny1)-607 R\ _________ Propanamide, N-(2,6-nonadieny1)-N-(2-propeny1)-608 R\ / Propanamide, N-(cyclopropylmethyl)-N-(2,6-nonadieny1)-609 0, / _______ Propanamide, nonadieny1)-_610 o, __________ Propanamide, N-(2,6-nonadieny1)-N-\--NY (2-methylpropy1)-m Propanaide, N-methyl-N-(2,6-nonadieny1)-N\
612 \___\ 0 Propanamide, N-ethyl-N-(2,6-nonadieny1)-_613= Propanamide, N-(2,6-n nonadiey1)-N-\._N
propyl-614 c,\ Propanamide, N-(1-methylethyl)-N-(2,6-nonadieny1)-615\¨\ 0 Propanamide, N-(1,1-dimethylethyl)-N-(2,6-nonadieny1)--N

Compound # Structure (Novel compounds) CA Index Name 616 o Propanamide, N-ethenyl-N-(2,6 -nonadieny1)-617 0 Propanamide, N-(2,6-nonadieny1)-N--\_ / (2-propeny1)--N
618 Propanamide, N-(cyclopropylmethyl)-N-(2,6-nonadieny1)-\--N
619 / Propanamide, N-butyl-N-(2,6-nonadieny1)-\ --N

Propanamide, N-(2,6-nonadieny1)-N-(2-methylpropy1)--N
o Acetamide, N-methyl-N-(2,6-621 nonadieny1)-622 o Acetamide, N-ethyl-N-(2,6-nonadieny1)-o\\ Acetamide, N-(2,6-nonadieny1)-N-= propyl-624 Acetamide, N-(1-methylethyl)-N---\=7-7 (2,6-nonadieny1)-Acetamide, N-(1,1-dimethylethyl)-N-625 (2,6-nonadieny1)-o Acetamide, N-ethenyl-N-(2,6-N nonadienyl) -o Acetamide, N-(2,6-nonadieny1)-N-(2-627 propeny1)-Compound # Structure (Novel compounds) CA Index Name Acetamide, N-(cyclopropylmethyl)-N-628 (2,6-nonadieny1)-Acetamide, N-butyl-N-(2,6-nonadieny1)-Acetamide, N-(2,6-nonadieny1)-N-(2-630 methylpropy1)-631 0, \--Acetamide, N-methyl-N-(2,6-nonadieny1)-tsk Acetamide, N-ethyl-N-(2,6-nonadieny1)-633 Acetamide, N-(2,6-nonadieny1)-N---\ propyl--N
634 Acetamide, N-(1-methylethyl)-N---\ (2,6-nonadieny1)-)--Acetamide, N-(1,1-dimethylethyl)-N-(2,6-nonadieny1)-'-N
Acetamide, N-ethenyl-N-(2,6-nonadieny1)-'-N
637___/ o Acetamide, N-(2,6-nonadieny1)-N-(2-propenyl) 638-1 Acetamide, N-(cyclopropylmethyl)-N-(2,6-nonadieny1)-Compound # Structure (Novel compounds) CA Index Name Acetamide, N-butyl-N-(2,6-nonadieny1)-\--N
640 Acetamide, N-(2,6-nonadieny1)-N-(2-methylpropy1)-- 641 Cyclopropanecarboxamide, N-[(2-[(3Z)-3-hexenyl]cyclopropyl]methy1]-N-methyl-'642 r_A\\_ots Cyclopropanecarboxamide, N-ethyl-N-([2-[(3Z)-3-\
hexenyl]cyclopropyl]methyll-643 Cyclopropanecarboxamide, N-[[2-[(3Z)-3-hexenyl]cyclopropyl]methyll-N-propyl-644 oH Cyclopropanecarboxamide, N-(1-methylethyl)-N-[(2-[(3Z)-3-hexenyl]cyclopropylimethy1]-645 Cyclopropanecarboxamide, N-(1,1-dimethylethyl)-N-H2-[(3Z)-3-)7 hexenyl]cyclopropyl]methy1]-F4/\ Cyclopropanecarboxamide, N-ethenyl-N-[[2-[(3Z)-3-hexenyl]cyclopropyl]methyl]-F-A

VA Cyclopropanecarboxamide, N-[[2-(3Z) -3-hexenyl]cyclopropyllmethyli-N-(2-propeny1)-648 Cyclopropanecarboxamide, N-[[2-[(3Z)-3-hexenyl]cyclopropyl]methyll-N-(cyclopropylmethyl)-649 Cyclopropanecarboxamide, N-butyl-N-([2-[(3Z)-3-hexenyl]cyclopropylimethy1]-650 Cyclopropanecarboxamide, N-[[2-[(3Z)-3-hexenyl]cyclopropyl]methyll-N-(2-methylpropy1)-Compound # Structure (Novel compounds) CA Index Name o 651 Cyclopropanecarboxamide, [(3Z)-3-hexenyl]cyclopropyl]methy1]-N-methyl-652 Cyclopropanecarboxamide, N-ethyl-N-[[2-[(3Z)-3-hexenyl]cyclopropyl]methy1]-o 653 Cyclopropanecarboxamide, N-[[2-[ (3Z) -3-\)17' hexenyl]cyclopropyl]methy1]-N-propyl-Cyclopropanecarboxamide, N-(1-654N)L7 methylethyl)-N-H2-[(3Z)-3-hexenyl]cyclopropyl]methy1]-655 Cyclopropanecarboxamide, N-(1,1-dimethylethyl)-N-H2-[(3Z)-3-NAT/
hexenyl]cyclopropyl]methy1]-656 Cyclopropanecarboxamide, N-ethenyl-N-[[2-[(3Z)-3-hexenyl]cyclopropyl]methyl]-657 Cyclopropanecarboxamide, N-[[2-[(3Z)-3-hexenyl]cyclopropyl]methy1]-N-(2-propeny1)-658 Cyclopropanecarboxamide, N-[[2-[(3Z)-3-NAT/
hexenyl]cyclopropyl]methy1]-N-(cyclopropylmethyl)-659 Cyclopropanecarboxamide, N-butyl-N-[(2-[(3Z)-3-hexenyl]cyclopropyl]methy1]-660 Cyclopropanecarboxamide, N-[(2-[(3Z)-3-hexenyllcyclopropyl]methyll-N-(2-methylpropy1)-Cyclopropanecarboxamide, N-[(2-[3-410 11 FsT7 cyclohexen-1-y1]-cyclopropy1)-methy1]-N-methyl-Cyclopropanecarboxamide, N-ethyl-N-[(2-[3- cyclohexen-l-y1]-cyclopropy1)-methy1]-Compound # Structure (Novel compounds) CA Index Name o Cyclopropanecarboxamide, N-[(2-[3-411 ' OI cyclohexen-l-yl]-cyclopropy1)-methy1]-N-propyl-664 Cyclopropanecarboxamide, N-(1-)1117 o methylethyl)-N-[(2-(3- cyclohexen-l-y1]-cyclopropy1)-methy1]-, 665 Cyclopropanecarboxamide, N-(1,1-0 1i. N --IL17 dimethylethyl)-N-[(2-(3-cyclohexen-1-y1]-cyclopropy1)-methyl]-o Cyclopropanecarboxamide, N-ethenyl-N-[(2-[3- cyclohexen-l-y1]-cyclopropy1)-methy1]-o __________________________________________________ Cyclopropanecarboxamide, N-[(2-[3-1\__ cyclohexen-l-y1]-cyclopropy1)-methy1]-N-(2-propeny1)-o Cyclopropanecarboxamide, N-[(2-[3-cyclohexen-1-y1]-cyclopropy1)-methy1]-N-(cyclopropylmethyl)-o Cyclopropanecarboxamide, N-butyl-N-410 /tNI7 [(2-[3-cyclohexen-1-y11-cyclopropy1)-methyl]-/
_ 410 IT7 Cyclopropanecarboxamide, N-[(2-[3-cyclohexen-1-y1]-cyclopropy1)-methy1]-N-(2-methylpropy1)-Cyclopropanecarboxamide, N-[(2-[3-cyclohexen-l-y1]-cyclopropy1)-o methy1]-N-methyl-T)LI7 _ Op o Cyclopropanecarboxamide, N-ethyl-N-[(2-[3-cyclohexen-l-y1]-cyclopropy1)-methyll-L, OP o ____________ Cyclopropanecarboxamide, N-[(2-[3-cyclohexen-l-y1]-cyclopropy1)-.
methyll-N-propyl-rj Compound # Structure (Novel compounds) CA Index Name 410 ______________ Cyclopropanecarboxamide, N-(1-methylethyl)-N-[(2-[3-cyclohexen-1-y1]-cyclopropy1)-methyl]-= N)T7' 410 _______________ Cyclopropanecarboxamide, N-(1,1-dimethylethyl)-N-[(2-[3-cyclohexen-1-y1]-cyclopropy1)-methyl]-F-676 ______________ 410 ______________ Cyclopropanecarboxamide, N-ethenyl-N-[(2-[3-cyclohexen-l-y1]-cyclopropy1)-methyll-N)LT7 o Cyclopropanecarboxamide, N-[(2-[3-cyclohexen-1-y1]-cyclopropy1)-methy1]-N-(2-propeny1)-l>"N
¨678 Cyclopropanecarboxamide, N-[(2-[3- -OP cyclohexen-l-y1]-cyclopropy1)-methy1]-N-(cyclopropylmethyl)-N)LT7 010 _______________ Cyclopropanecarboxamide, N-butyl-N-[(2-[3-cyclohexen-l-y1]-cyclopropy1)-methyl]-= N)Y
-680 Cyclopropanecarboxamide, N-[(2-[3-410 cyclohexen-1-y1]-cyclopropy1)-methy1]-N-(2-methylpropy1)-= N)LT7 o Cyclopropanecarboxamide, N-[(1-methy1-2-phenyl-cyclopropy1)-Olt methy1]-N-methyl-o Cyclopropanecarboxamide, N-ethyl-N-ilt 44 N'I'T/
[(1-methyl-2-phenyl-cyclopropy1)-methyl]-. Compound # Structure (Novel compounds) CA Index Name o Cyclopropanecarboxamide, N-[(1-4 )..4 IJ v methy1-2-phenyl-cyclopropy1)-methy1]-N-propyl-o Cyclopropanecarboxamide, N-(1-010 ' 767 methylethyl)-N-[(1-methy1-2-phenyl-cyclopropy1)-methy1]-o Cyclopropanecarboxamide, N-(1,1-4 , dimethylethyl) -N- [ (I-methyl-2-NAV/
phenyl-cyclopropy1)-methyl]-o Cyclopropanecarboxamide, N-ethenyi-Olt N --:,.. N-[(1-methy1-2-phenyl-cyclopropy1)-methyl]-o Cyclopropanecarboxamide, N-[(1-687 N:IL.1,1 methy1-2-phenyl-cyclopropyl)-methy1]-N-(2-propeny1)-o Cyclopropanecarboxamide, N-[(1-40 7/Y methy1-2-phenyl-cyclopropy1)-methy1]-N-(cyclopropylmethyl)-o Cyclopropanecarboxamide, N-butyl-N-I
[(1-methyl-2-phenyl-cyclopropyl)-methyl] -o Cyclopropanecarboxamide, N-[(1-010 4 N--1-7 methy1-2-phenyl-cyclopropy1)-methy1]-N-(2-methylpropy1)-691 Cyclopropanecarboxamide, N-[(1-1 methy1-2-phenyl-cyclopropy1)-NAo methy1]-N-methyl-`v I
IP o Cyclopropanecarboxamide, N-ethyl-N-[(1-methyl-2-phenyl-cyclopropy1)-methyl]-li wji'v ) 010 o Cyclopropanecarboxamide, N-[(1-methyl-2-phenyl-cyclopropy1)-methy1]-N-propyl-110, N Av ) Compound # Structure (Novel compounds) CA Index Name Cyclopropanecarboxamide, N-(1-methylethyl)-N-[(1-methy1-2-phenyl-cyclopropy1)-methy1]-N)'07 Cyclopropanecarboxamide, N-(1,1-dimethylethyl)-N-[(1-methyl-2-phenyl-cyclopropy1)-methyl]-0. isr-Lv >( 410 Cyclopropanecarboxamide, N-ethenyl-N-[(1-methyl-2-phenyl-cyclopropy1)-methyl]-Wj'Av I
_______________________________________________________________________________ ________ 410 0 Cyclopropanecarboxamide, N-[(1-methyl-2-phenyl-cyclopropy1)-methyl]

-N-(2-propeny1)-0. N)C7 /j 410 ________________________________________________ Cyclopropanecarboxamide, N-[(1-methyl-2-phenyl-cyclopropy1)-methy1]-N-(cyclopropylmethyl)-0. lµrjtv L.T7 Cyclopropanecarboxamide, N-butyl-N-[(1-methy1-2-phenyl-cyclopropy1)-methyl]-Isl'A'v /j -700 Cyclopropanecarboxamide, N-[(1-i methy1-2-phenyl-cyclopropy1)-methyll-N-(2-methylpropy1)-1=1)17 111)7. Cyclopropanecarboxamide, N-[(2-methyl-2-phenyl-cyclopropy1)-methyll-N-methyl-o Cyclopropanecarboxamide, N-ethyl-N-Olt :1-kV [(2-methy1-2-phenyl-cyclopropy1)-methyl]--703 o Cyclopropanecarboxamide, N-[(2-OIL 1 ' methy1-2-phenyl-cyclopropy1)-methy1]-N-propyl-Compound # Structure (Novel compounds) CA Index Name o Cyclopropanecarboxamide, N-(1-' ;)\Y methylethyl)-N-[(2-methyl-2-phenyl-cyclopropy1)-methyl]-o Cyclopropanecarboxamide, N-(1,1-dimethylethyl)-N-[(2-methy1-2-phenyl-cyclopropy1)-methy1]-o Cyclopropanecarboxamide, N-ethenyl-N-[(2-methy1-2-phenyl-cyclopropy1)-methyl]-o Cyclopropanecarboxamide, N-[(2-'707 410 OP. t4)1.y/
methy1-2-phenyl-cyclopropy1)-methy1]-N-(2-propeny1)-o Cyclopropanecarboxamide, N-[(2-708 =
)r methy1-2-phenyl-cyclopropy1)-methy1]-N-(cyclopropylmethyl)-o Cyclopropanecarboxamide, N-butyl-N-01$ N'7 [(2-methyl-2-phenyl-cyclopropy1)-methyl] -o Cyclopropanecarboxamide, N-[(2-011 10. N)-7 methyl-2-phenyl-cyclopropy1)-methy1]-N-(2-methylpropy1)-410 Cyclopropanecarboxamide, N-[(2-methyl-2-phenyl-cyclopropy1)-methy1]-N-methyl-010 Cyclopropanecarboxamide, N-ethyl-N-[(2-methyl-2-phenyl-cyclopropy1)-methyl]-= N)1.1 Cyclopropanecarboxamide, N-[(2-410 methyl-2-phenyl-cyclopropy1)-methy1]-N-propyl-= 71-ILT7' 410 Cyclopropanecarboxamide, N-(1-methylethyl)-N-[(2-methy1-2-phenyl-cyclopropy1)-methy1]-= N'ki7 Compound # Structure (Novel compounds) CA Index Name 410 _________________________________________________ Cyclopropanecarboxamide, N-(1,1-dimethylethyl)-N-[(2-methyl-2-phenyl-cyclopropy1)-methyl]-1111. N)Y
410 _________________________________________________ Cyclopropanecarboxamide, N-ethenyl-N-[(2-methy1-2-phenyl-cyclopropy1)-methyl]-111111.
410 _________________________________________________ Cyclopropanecarboxamide, N-[(2-methy1-2-phenyl-cyclopropy1)-methyl]-N-(2-propeny1)-1111. Wk7 010 ________________________________________________ Cyclopropanecarboxamide, N-[(2-methyl-2-phenyl-cyclopropy1)-methy1]-N-(cyclopropylmethyl)-'N)Y
410 0 ____________ Cyclopropanecarboxamide, N-butyl-N-[(2-methyl-2-phenyl-cyclopropy1)-methyl]-rN)Y
____________________________________________________ Cyclopropanecarboxamide, N-[(2-410 methy1-2-phenyl-cyclopropy1)-methy1]-N-(2-methylpropy1)-I%1)Y
Cyclopropanecarboxamide, N-[(1-methy1-2-[(3Z)-3-hexeny1]-cyclopropyl) -methyl] -N-methyl-722 (pH Cyclopropanecarboxamide, N-ethyl-N-[(1-methy1-2-[(3Z)-3-hexeny1]-cyclopropy1)-methy1]-723 Cyclopropanecarboxamide, N-[(1-methy1-2-[(3Z)-3-hexeny1]-cyclopropy1)-methy1]-N-propyl-724 )--1 Cyclopropanecarboxamide, N-(1-methylethyl)-N-[(1-methy1-2-[(32)-3-hexenyl]-cyclopropy1)-methy1]-Compound # Structure (Novel compounds) CA Index Name Cyclopropanecarboxamide, N-(1,1-dimethylethyl)-N-[(1-methy1-2--7) [(3Z)-3-hexeny1]-cyclopropy1)-methy1]-726 Cyclopropanecarboxamide, N-ethenyl-_\ A oN, 1 N-[(1-methy1-2-[(3Z)-3-hexeny1]-cyclopropy1)-methyl]-727 c--1 Cyclopropanecarboxamide, N-[(1-methyl-2-[(3Z)-3-hexeny1]-cyclopropy1)-methy1]-N-(2-propeny1)-728 sc--1 Cyclopropanecarboxamide, N-[(1-methyl-2-[(3Z)-3-hexeny1]-LLN
cyclopropy1)-methy1]-N-(cyclopropylmethyl)-729 ,ix_o /
N \ Cyclopropanecarboxamide, N-butyl-N-[(1-methy1-2-[(3Z)-3-hexeny1]-\____/
cyclopropy1)-methy1]-, 730 cH Cyclopropanecarboxamide, N-[(1-methyl-2-[(3Z)-3-hexeny1]-cyclopropyl) -methyl] -N- (2-methylpropyl) -731 o Cyclopropanecarboxamide, N-[(1-methy1-2-[(3Z)-3-hexeny1]-I IIATI cyclopropy1)-methyll-N-methyl-, 732 o Cyclopropanecarboxamide, N-ethyl-N-[(1-methy1-2-[(3Z)-3-hexenyl]-''1'-'.'----'-'7<h)-11'.V cyclopropy1)-methy1]-i 733 Cyclopropanecarboxamide, N-[ (1-methyl-2- [ (3Z) -3-hexenyl] -N)Y
cyclopropyl) -methyl] -N-propyl-' 734 o Cyclopropanecarboxamide, N-(1-methylethyl)-N-[(1-methy1-2-[(3Z)-3-hexeny1]-cyclopropy1)-methyll-735 o Cyclopropanecarboxamide, N-(1,1-dimethylethyl)-N-[(1-methy1-2-[(3Z)-3-hexenyll-cyclopropy1)-methyl] -736 o Cyclopropanecarboxamide, N-etheny1-N-[(1-methy1-2-[(3Z)-3-hexeny1]-cyclopropy1)-methyll-Compound # Structure (Novel compounds) CA Index Name 737 \ o Cyclopropanecarboxamide, N-[(1--, methy1-2-[(3Z)-3-hexenyl]-N'IL-7 cyclopropy1)-methyl]-N-(2-propeny1)-738 o Cyclopropanecarboxamide, N-[(1-methyl-2-[(3Z)-3-hexeny1]-A'"=-....."...---..."--"..-"<::::hNjty 2 cyclopropy1)-methy1]-N-(cyclopropylmethyl)-739 o Cyclopropanecarboxamide, N-butyl-N-1 N)T7 [(1-methy1-2-[(3Z)-3-hexeny1]-cyclopropy1)-methy1]-740 o Cyclopropanecarboxamide, N-[(1-methyl-2-[(3Z)-3-hexeny1]-..--4 cyclopropy1)-methyll-N-(2-methylpropy1)-741 Cyclopropanecarboxamide, N-[(2-phenyl-cyclopropy1)-methy1]-N-methyl-o Cyclopropanecarboxamide, N-ethyl-N-40 JILT7 [(2-phenyl-cyclopropy1)-methyl]-743 o Cyclopropanecarboxamide, N-[(2-010 N'T7 phenyl-cyclopropy1)-methy1]-N-propyl-o Cyclopropanecarboxamide, N-(1-010 ii. N7' methylethyl)-N-[(2-phenyl-cyclopropy1)-methy1]-o 745 Cyclopropanecarboxamide, N-(1,1-Olt 4),T7 dimethylethyl)-N-[(2-phenyl-cyclopropy1)-methy1]-o 746 Cyclopropanecarboxamide, N-ethenyl-010 ),-,T7 N-[(2-methy1-2-phenyl-cyclopropy1)-methyl] -747 :11T7 Cyclopropanecarboxamide, N-[(2-phenyl-cyclopropy1)-methyl]-N-(2-propeny1)-o Cyclopropanecarboxamide, N-[(2-410 0. NAT/
phenyl-cyclopropy1)-methy1]-N-(cyclopropylmethyl)-Compound # Structure (Novel compounds) CA Index Name o Cyclopropanecarboxamide, N-butyl-N-010 IP1 [(2-phenyl-cyclopropy1)-methyll-o Cyclopropanecarboxamide, N-[(2-phenyl-cyclopropy1)-methyl]-N-(2-methylpropy1)-410 0 Cyclopropanecarboxamide, N-[(2-phenyl-cyclopropy1)-methy1]-N-methyl-N)1'10( 410 _______________________________________________ Cyclopropanecarboxamide, N-ethyl-N-[(2-phenyl-cyclopropy1)-methyl]-N)INT7 Cyclopropanecarboxamide, N-[(2-010 phenyl-cyclopropy1)-methy1]-N-propyi-00, N)Y
754 Cyclopropanecarboxamide, N-(1-methylethyl)-N-[(2-phenyl-cyclopropy1)-methy1]-755 Cyclopropanecarboxamide, N-(1,1-dimethylethyl)-N-[(2-phenyl-cyclopropy1)-methyl]-,11\
Cyclopropanecarboxamide, N-ethenyl-110 N-[(2-methy1-2-phenyl-cyclopropy1)-methy1]-757 ___________________________________________ 410 Cyclopropanecarboxamide, N-[(2-phenyl-cyclopropy1)-methy1]-N-(2-propeny1)-po. NAV
==_,) Cyclopropanecarboxamide, N-[(2-410 phenyl-cyclopropy1)-methy1]-N-(cyclopropylmethyl)-110.

Compound # Structure (Novel compounds) CA Index Name 759 Cyclopropanecarboxamide, N-butyl-N-I [(2-pheny1-cyclopropy1)-methyl]-N)L1 410 ________________________________________________ Cyclopropanecarboxamide, N-[(2-phenyl-cyclopropy1)-methy1]-N-(2-methylpropy1)-po. N-kry o Propanamide, N-[(2-methy1-2-[4-N11)c( methyl-3-pentenyl]-cyclopropy1)-methy1]-N-methy1-2,2-dimethyl-iL Propanamide, N-ethyl-N-[(2-methyl-2-[4-methy1-3-penteny1]-N( 7) cyclopropy1)-methy1]-2,2-dimethyl-Propanamide, N-[(2-methy1-2-[4-)L, methy1-3-penteny1]-cyclopropy1)-methy1]-N-propy1-2,2-dimethyl-o __________________________________________________ Propanamide, N-(1-methylethyl)-N-[(2-methyi-2-[4-methy1-3-pentenyl]-cyclopropy1)-methy1]-2,2-dimethyl-o Propanamide, N-(1,1-dimethylethyl)-N)L
N-[ (2-methyl-2-[4-methyl-3-pentenyl]-cyclopropy1)-methyl]-2,2-dimethyl--766 Propanamide, N-ethenyl-N-[(2-N)C( methy1-2-[4-methy1-3-pentenyl]-cyclopropy1)-methy1]-2,2-dimethyl-o Propanamide, N-[(2-methy1-2-[4-N)C( methyl-3-penteny1]-cyclopropy1)-methy1]-N-(2-propeny1)-2,2-dimethyl--768 o Propanamide, N-[(2-methyl-2-[4-NA methyl-3-penteny1]-cyclopropy1)-methy1]-N-(cyclopropylmethyl)-2,2-dimethyl--769 o Propanamide, N-butyl-N-[(2-methy1-1 )< 2-[4-methy1-3-penteny1]-cyclopropy1)-methy1]-2,2-dimethyl-Compound # Structure (Novel compounds) CA Index Name _ ) o Propanamide, N-[(2-methyl-.2-[4-1,1 , methyl-3-penteny1]-cyclopropyl) ¨

N
methyl]-N-(2-methylpropy1)-2,2-dimethyl-771 Propanamide, N-[(2--methyl-2-[4-o methy1-3-pentenyl]-cyclopropy1)-N).L methyl)-N-methy1-2,2-dimethyl-I
-772 Propanamide, N-ethyl-N-[(2-methyl-2-(4-methy1-3-pentenyl]-cyclopropy1)-methy11-2,2-dimethyl-cjY
773 Propanamide, N-[(2-methy1-2-(4---',.----'-X 0 methy1-3-penteny1)-cyclopropy1)-LtsA, methyl)-N-propy1-2,2-dimethyl-/
774 Propanamide, N-(1-methylethy1)-N-o [(2-methy1-2-[4-methy1-3-penteny1]-Ltsi) cyclopropy1)-methyl)-2,2-dimethyl-)\ .
775 Propanamide, N-(1,1-dimethylethyl)-N-[ (2-methyl-2-[4-methyl-3-o N'IlX penteny1]-cyclopropy1)-methyll-2,2-----,4- dimethyl-_______________________________________________________________________________ _________ _ 776 Propanamide, N-ethenyl-N-[(2-o methyl-2-[4-methyl-3-penteny1)-cyclopropy1)-methyl)-2,2-dimethyl--777 Propanamide, N-[(2-methy1-2-[4-TA
o methyl-3-penteny1]-cyclopropy1)-methy1]-N-(2-propeny1)-2,2-,( dimethyl-, 778 Propanamide, N-[ (2-methyl-2-[4-1 o methyl-3-penteny1]-cyclopropy1)-rr'lLi< methyll-N-(cyclopropylmethyl)-2,2-dimethyl-_______________________________________________________________________________ _________ _ __________________ _ ______________________________ 779 Propanamide, N-butyl-N-[(2-methyl-o 2-[4-methy1-3-penteny1]-cyclopropy1)-methyl)-2,2-dimethyl-Propanamide, N-[(2-methy1-2-[4-o methyl-3-penteny1]-cyclopropy1)-methyl)-N-(2-methylpropy1)-2,2-dimethyl-Compound # Structure (Novel compounds) CA Index Name o Butanamide, N-[(2-methyl-2-[4-methyl-3-penteny1]-cyclopropy1)-I methy1]-N-methyl-- 1 o Butanamide, N-ethyl-N-[(2-methyl-2--N.
[4-methyl-3-penteny1]-cyclopropyl) methyl]-.
o Butanamide, N-[(2-methyl-2-[4--N.
methyl-3-penteny1]-cyclopropy1)-) methy1]-N-propyl-o Butanamide, N-(1-methylethyl)-N-[(2-methyl-2-[4-methyl-3-pentenyl]-cyclopropy1)-methy1]-785 o ______________ Butanamide, N-(1,1-dimethylethyl)-N-Jt,--^ N-[(2-methy1-2-[4-methy1-4\ pentenyl]-cyclopropy1)-methyl].
. o Butanamide, N-ethenyl-N-[(2-methyl-2-[4-methy1-3-penteny1]-cyclopropy1)-methy1]-_ o Butanamide, N-{(2-methyl-2-[4-L", methyl-3-penteny1]-cyclopropy1)-1\--- methyl]-N-(2-propeny1)-_ N.A
o Butanamide, N-[(2-methyl-2-[4-methyl-3-penteny1]-cyclopropy1)-.) methy1]-N-(cyclopropylmethyl)-o Butanamide, N-butyl-N-[(2-methy1-2-_______________________________________________________________________________ _________ _ N)-=,,µ [4-methy1-3-penteny1]-cyclopropy1)-Ymethyl] -o Butanamide, N-[(2-methyl--2--[4--.
methyl-3-pentenyl]-cyclopropy1)-\-) methyl]-N-(2-methylpropy1)-791 Butanamide, N-[(2-methy1-2-[4-o methyl-3-penteny1]-cyclopropy1)-rsr,k, methy1]-N-methyl-I
792 Butanamide, N-ethyl-N-[(2-methy1-2- , --)<L o [4-methy1-3-penteny1]-cyclopropy1)-methy1]-) Compound # Structure (Novel compounds) CA Index Name 793 Butanamide, N-[(2-methy1-2-[4-methy1-3-penteny1]-cyclopropy1)-N methy1]-N-propyl-794 Butanamide, N-(1-methylethyl)-N-[(2-methy1-2-(4-methyl-3-pentenyl]-cyclopropy1)-methy1]-7j\
795 Butanamide, N-(1,1-dimethylethyl)-N-[(2-methy1-2-[4-methy1-3-penteny1]-cyclopropy1)-methyl]-796 Butanamide, N-ethenyl-N-[(2-methyl-2-[4-methy1-3-penteny1]-cyclopropy1)-methy1]-797 Butanamide, N-[(2-methy1-2-[4-methy1-3-penteny1]-cyclopropyl)-N methy1]-N-(2-propeny1)-798 Butanamide, N-[(2-methy1-2-[4-methyl-3-penteny1]-cyclopropy1)-methy1]-N-(cyclopropylmethyl)-799 Butanamide, N-butyl-N-[(2-methy1-2-[4-methy1-3-pentenyl]-cyclopropy1)-methy1]-./) 800 Butanamide, N-[(2-methyl-2-[4--,.
methyl-3-penteny1]-cyclopropy1)-methyll-N-(2-methylpropy1)-Propanamide, N-[(1-methyl-2-phenyl-cyclopropy1)-methy1]-N-methyl-0 Propanamide, N-ethyl-N-[(1-methyl-2-phenyl-cyclopropy1)-methyl)-0 Propanamide, N-[(1-methy1-2-phenyl-cyclopropy1)-methyl]-N-propyl-Compound # Structure (Novel compounds) CA Index Name o Propanamide, N-(1-methylethy1)-N-410 4 N'-L---[(1-methyl-2-phenyl-cyclopropy1)-methyl]-o Propanamide, N-(1,1-dimethylethyl)-Olt 4 N'IL"------- N-[(1-methy1-2-phenyl-cyclopropy1)-"- methyl]-, o Propanamide, N-ethenyl-N-[(1-40 4 NrLv methyl-2-phenyl-cyclopropy1)-methyl]-_______________________________________________________________________________ _________ _ o Propanamide, N-[(1-methyl-2-phenyl-40 4 N -J-,, .-----=-- cyclopropy1)-methyl]-N-(2-propeny1)-o Propanamide, N-[(1-methyl-2-phenyl-808 4 cyclopropy1)-methyl]-N-1111 1 N>,, (cyclopropylmethyl)---- o Propanamide, 809 N-butyl-N-[(1-methyl-Olt2-phenyl-cyclopropy1)-methy1]-\---.\----.
I o __________ Propanamide, N-[(1-methyl-2-phenyl-4cyclopropy1)-methy1]-N-(2-2)Lõ,, methylpropy1)-m _811 . ____ Propanamide, N-[(1-ethy1-2-phenyl-110 cyclopropy1)-methy1]-N-methyl-o K., 0. N
I
110 o Propanamide, N-ethyl-N-[(1-methyl-2-phenyl-cyclopropy1)-methy1]-( 410 o ____________ Propanamide, N-[(1-methy1-2-phenyl-cyclopropy1)-methyll-N-propyl-110 o Propanamide, N-(1-methylethyl)-N-[(1-methyl-2-phenyl-cyclopropy1)-methyl]-Compound # Structure (Novel compounds) CA Index Name 110 _______________________________________________ Propanamide, N-(1,1-dimethylethyl)-N-[(1-methyl-2-phenyl-cyclopropy1)-methyl)-410 ________________________________________________ Propanamide, N-ethenyl-N-[(1-methyl-2-phenyl-cyclopropy1)-methyl]-410 ________________________________________________ Propanamide, N-[(1-methyl-2-phenyl-cyclopropy1)-methyl]-N-(2-propeny1)-0o.

Propanamide, N-[(1-methy1-2-pheny1-cyclopropy1)-methy1]-N-(cyclopropylmethyl)-LT"r42_,-410 ________________________________________________ Propanamide, N-butyl-N-[(1-methy1-2-phenyl-cyclopropy1)-methyl]-110 _______________________________________________ Propanamide, N-[(1-methy1-2-pheny1-cyclopropy1)-methyll-N-(2-)/ methylpropy1)-N
-821 o Propanamide, N-[(2-methy1-2-phenyl-)1,õ- cyclopropy1)-methyl]-N-methyl-Propanamide, N-ethyl-N-[(2-methyl-2-phenyl-cyclopropy1)-methy1]-o Propanamide, N-[(2-methy1-2-phenyl-)Lõ cyclopropy1)-methyl]-N-propyl-o Propanamide, N-(1-methylethyl)-N-Olt [(2-methy1-2-phenyl-cyclopropy1)-methy1]-Compound # Structure (Novel compounds) CA Index Name o Propanamide, N-(1,1-dimethylethyl)--N-[(2-methy1-2-phenyl-cyclopropy1)-methy1]-o Propanamide, N-ethenyl-N-[(2-826 _______________ 410 methyl-2-phenyl-cyclopropy1)-methyl]-o Propanamide, N-[(2-methy1-2-phenyl-cyclopropy1)-methy1]-N-(2-propeny1)-o Propanamide, N-[ (2-methyl-2-phenyl--cyclopropy1)-methy1]-N-=
(cyclopropylmethyl)-o Propanamide, N-butyl-N-[(2-methyl-010 P ' 2-phenyl-cyclopropy1)-methy1]-o Propanamide, N-[ (2-methyl-2-phenyl.-01$ 10.N cyclopropy1)-methyl]-N-(2-methylpropy1)-831 Propanamide, N-[(2-methy1-2-phenyl-cyclopropy1)-methy1]-N-methyl-f;1 832 Propanamide, N-ethyl-N-[(2-methyl-2-phenyl-cyclopropy1)-methy1]-10, 010 _______________________________________________ Propanamide, N-[(2-methy1-2-phenyl-cyclopropy1)-methy1]-N-propyl-010 _______________________________________________ Propanamide, N-(1-methylethyl)-N-[(2-methy1-2-phenyl-cyclopropy1)-N)(õv methyl]-Compound # Structure (Novel compounds) CA Index Name 110 ______________ Propanamide, N-(1,1-dimethylethyl)-N-[(2-methy1-2-phenyl-cyclopropy1)-N)L"r.
methyl)-110 ______________ Propanamide, N-ethenyl-N-[(2-methyl-2-phenyl-cyclopropy1)-N methyl)-410 ______________ Propanamide, N-[(2-methy1-2-phenyl-cyclopropyl)-methyl]-N-(2-propeny1)-N
110 ______________ Propanamide, N-[(2-methy1-2-phenyl-cyclopropy1)-methy1]-N-(cyclopropylmethyl)-410 ______________ Propanamide, N-butyl-N-[(2-methy1-2-phenyl-cyclopropy1)-methyl]-N \
110 _______________ Propanamide, N-C(2-methy1-2-phenyl-cyclopropy1)-methyl]-N-(2-methylpropy1)-111. N
o Acetamide, N-[(1-methyl-2-phenyl-841 ________________________________________________ 4110 4 N-k cyclopropy1)-methy1]-N-methyl-842Acetamide, N-ethyl-N-[(1-methyl-2-Olt 4 N) L, phenyl-cyclopropy1)-methyl)-843 o _________ Acetamide, N-H1-methyl-2-phenyl-4 cyclopropy1)-methy1]-N-propyl-844 o Acetamide, N-(1-methylethyl)-N-[(1-= 4 methy1-2-phenyl-cyclopropy1)-methy1]-Compound # Structure (Novel compounds) CA Index Name Acetamide, N-(1,1-dimethylethyl)-N-40 NJ [(1-methyl-2-phenyl-cyclopropy1)-methyl]-Acetamide, N-ethenyl-N-[(1-methyl-410 4 NjL.
2-phenyl-cyclopropy1)-methyl)-Acetamide, N-[(1-methy1-2-phenyl-N
cyclopropy1)-methy1]-N-(2-L. propeny1)-Acetamide, N-[(1-methyl-2-phenyl-cyclopropy1)-methy1]-N-100 (cyclopropylmethyl)-Acetamide, N-butyl-N-[(1-methyl-2-N
phenyl-cyclopropy1)-methyl]-Acetamide, N-[(1-methyl-2-phenyl-N' cyclopropy1)-methyl]-N-(2-methylpropy1)-110 ____________ Acetamide, N-{ (1-methyl-2-phenyl-cyclopropy1)-methyll-N-methyl-110 Acetamide, N-ethyl-N-[(1-methy1-2-phenyl-cyclopropy1)-methy1]-pi" N
410 ____________ Acetamide, N-[(1-methy1-2-phenyl-cyclopropy1)-methy1]-N-propyl-po. N
410 ____________ Acetamide, N-(1-methylethyl)-N-[(1-methyl-2-phenyl-cyclopropy1)-methyl]-hrk )K
Acetamide, N-(1,1-dimethylethyl)-N-[(1-methyl-2-phenyl-cyclopropy1)-methyl]-Compound # Structure (Novel compounds) CA Index Name Acetamide, N-ethenyl-N-[(1-methyl-2-phenyl-cyclopropy1)-methy1]-10.
857 I Acetamide, N-[(1-methy1-2-phenyl-cyclopropy1)-methyl]-N-(2-tsjL propeny1)-r _______________________________________________________________________________ _____ 010 Acetamide, N-[(1-methy1-2-phenyl-cyclopropy1)-methyl]-N-(cyclopropylmethyl)-11) _______________________________________________________________________________ ______ 410 Acetamide, N-butyl-N-[(1-methy1-2-phenyl-cyclopropy1)-methy1]-410 _______________________________________________ Acetamide, N-[(1-methy1-2-phenyl-cyclopropy1)-methy1]-N-(2-methylpropy1)-t,1L
-861Acetamide, N-[(2-methy1-2-phenyl-J11., cyclopropy1)-methy1]-N-methyl-Acetamide, N-ethyl-N-[(2-methyl-2-N2, phenyl-cyclopropy1)-methyl]--863Acetamide, N-[(2-methy1-2-phenyl-Jk, 410 cyclopropy1)-methy1]-N-propyl-Acetamide, N-(1-methylethyl)-N-[(2-Olt ,Z, methy1-2-phenyl-cyclopropy1)-methyl]-865 0 Acetamide, N-(1,1-dimethylethyl)-N-410[(2-methy1-2-phenyl-cyclopropy1)-methyl]-0 Acetamide, N-ethenyl-N-[(2-methyl-. 010 po 2-phenyl-cyclopropy1)-methy1]-=

Compound # Structure (Novel compounds) CA Index Name o Acetamide, N-[(2-methy1-2-phenyl-.[Lõ cyclopropy1)-methyll-N-(2-_______________________________________________________________________________ _____ 410 propeny1)-Acetamide, N-[(2-methy1-2-phenyl-411 11 1 cyclopropy1)-methy1]-N-(cyclopropylmethyl)-o Acetamide, N-butyl-N-[(2-methy1-2-OltZ, phenyl-cyclopropy1)-methy1]-o Acetamide, N-[(2-methy1-2-phenyl-010 cyclopropy1)-methyl]-N-(2-methylpropy1)-Acetamide, N-[ (2-methyl-2-phenyl-cyclopropy1)-methy1]-N-methyl-NJ'L-Acetamide, 872N-ethyl-N-[(2-methy1-2-phenyl-cyclopropy1)-methy1]-NJL

Acetamide, N-[(2-methy1-2-phenyl-cyclopropy1)-methyl]-N-propyl-410 ____________ Acetamide, N-(1-methylethyl)-N-[(2-methyl-2-phenyl-cyclopropyl)-111110. N
methyl]-110 Acetamide, N-(1,1-dimethylethyl)-N-[(2-methyl-2-phenyl-cyclopropyl)-jj methyll-Acetamide, N-ethenyl-N-[(2-methyl-2-phenyl-cyclopropy1)-methyl]-Compound # Structure (Novel compounds) CA Index Name Acetamide, N-[(2-methy1-2-phenyl-cyclopropy1)-methyl]-N-(2-propeny1)-00.
010 ________________________________________________ Acetamide, N-[ (2-methyl-2-phenyl-cyclopropy1)-methy1]-N-(cyclopropylmethyl)-N)t' 010 ________________________________________________ Acetamide, N-butyl-N-[(2-methy1-2-phenyl-cyclopropy1)-methyl]-N)1'' 110 _______________________________________________ Acetamide, N-[(2-methy1-2-phenyi-cyclopropyl)-methyl]-N-(2-methylpropy1)-01.
Acetamide, N-[(1-methy1-2-[(3Z)-3---hexeny1]-cyclopropy1)-methyl]-N-methyl-o Acetamide, N-ethyl-N-[(1-methy1-2-[(3Z)-3-hexeny1]-cyclopropy1)-methyl] -Acetamide, N-[(1-methy1-2-[(3Z)-3---\ /--/ACN¨Th hexeny1]-cyclopropy1)-methyl]-N-- propyl-884 o Acetamide, N-(1-methylethyl)-N-[(1-methyl-2-[(3Z)-3-hexenyl]-cyclopropy1)-methyll-c> Acetamide, N-(1,1-dimethylethyl)-N-[(1-methy1-2-[(3Z)-3-hexeny1]-cyclopropy1)-methy1]-Acetamide, N-ethenyl-N-[(1-methy1=--2-[(3Z)-3-hexeny1]-cyclopropy1)-methyll-Compound # Structure (Novel compounds) CA Index Name I
A Acetamide, N-[(1-methyl-2-[(3Z)-3-oN
hexenyll-cyclopropy1)-methyl]-N-(2-r_ propeny1)-Acetamide, N-[(1-methy1-2-[(3Z)-3---\ /---'(-- N' hexeny1]-cyclopropy1)-methyl]-N-'N7 (cyclopropylmethyl)-889 (3 Acetamide, N-butyl-N-[(1-methy1-2-[(3Z)-3-hexeny1]-cyclopropy1)-methyl]-.
_ _ Acetamide, N-[(1-methy1-2-[(3Z)-3-¨\ /---A--: hexeny1]-cyclopropy1)-methyl]-N-(2-methylpropy1)-_ 891 o Acetamide, N-[(1-methyl-2-[(3Z)-3-hexeny1]-cyclopropy1)-methyl]-N-I methyl-, -892 Acetamide, N-ethyl-N-[(l-methyl-2-_ )('' [(3Z)-3-hexenY1]-cYclopropY1)-N
) methyl]-_ 893 o Acetamide, N-[(1-methyl-2-{(3Z)-3-_ hexeny1]-cyclopropyl)-methyl]-N-propyl-894 o Acetamide, N-(1-methylethyl)-N-[(1-methy1-2-[(3Z)-3-hexeny1]-cyclopropy1)-methy1]-, .
895 --, o Acetamide, N-(1,1-dimethylethyl)-N-[(1-methy1-2-[(3Z)-3-hexeny1]-)\-- cyclopropy1)-methy1]-_ _ 896 Acetamide, N-ethenyl-N-[(1-methyl-,--, 13 2-[(3Z)-3-hexenyl]-cyclopropy1)-methyl]-_ 897 o Acetamide, N-[(1-methy1-2-[(3Z)-3-nexeny1]-cyclopropy1)-methyl]-N-(2-propeny1)-, _ 898 o Acetamide, N-[ (1-methyl-2-[(3Z)-3-N'k hexeny1]-cyclopropy1)-methyl]-N-(cyclopropylmethyl)-Compound # Structure (Novel compounds) CA Index Name 899 ., ' Acetamide, N-butyl-N-[(1-methyl-2-[(3Z)-3-hexenyl]-cyclopropy1)-I, methyl]-900 ., o Acetamide, N-{(1-methyl-2-[(3Z)-3-I N) hexeny1]-cyclopropy1)-methyl]-N-(2-methylpropy1)-o Propanamide, N-[(2-[3-cyclohexen-1-0 Nil y1]-cyclopropy1)-methyl]-N-methyl-o Propanamide, N-ethyl-N-[(2-[3-cyclohexen-1-y1]-cyclopropy1)-methyl]-903 o __________ Propanamide, N-[(2-[3-cyclohexen-1-Aõõ--0 N( y1]-cyclopropy1)-methyl]-N-propyl-_ _______________________________________________________________________________ _______ o Propanamide, N-(1-methy1ethyl)-N-)1.,.,,- [(2-[3- ,,J010 cyclohexen-1-y1]-N \ cyclopropy1)-methyl]-905 ____________________ 410 o Propanamide, N-(1,1-dimethylethyl)-Ji.õ, 0. N N-[(2-[3-cyclohexen-l-y1]-cyclopropy1)-methy1]-/\
o Propanamide, N-ethenyl-N-[(2-[3-.J.L,, 0 , t cyclohexen-l-y1]-cyclopropy1)-methyll-o Propanamide, N-[(2-[3-cyclohexen-1-)1,õ
N y1]-cyclopropy1)-methyll-N-(2-ipropeny1)-L----=--o 908 Propanamide, N-[(2-[3-cyclohexen-1-)1._ 410 ' N,, yll-cyclopropy1)-methy1]-N-(cyclopropylmethyl)-o _______________________________________________________________________________ _____________________ 909 Propanamide, N-butyl-N-[(2-[3-)..Lõ
40 1µ1,, cyclohexen-l-y11-cyclopropy1)-methy1]-40 )L

o Propanamide, N-[(2-[3-cyclohexen-1-. ,,,, p N
y1]-cyclopropy1)-methyll-N-(2-methylpropy1)-Compound # Structure (Novel compounds) CA Index Name 410 0 Propanamide, N-[(2-[3-cyclohexen-l-y1]-cyclopropy1)-methyl]-N-methyl-110 0 Propanamide, N-ethyl-N-[(2-[3-cyclohexen-1-y1 cyclopropy1]-methyl)-N) 110 Propanamide, N-[(2-[3-cyclohexen-1-y1]-cyclopropy1)-methyll-N-propyl-N
o Propanamide, N-(1-methylethyl)-N-[(2-[3- cyclohexen-1-y1]-N cyclopropy1)-methyl]-410 _____________ Propanamide, N-(1,1-dimethylethyl)-N-[(2-[3-cyclohexen-1-y1]-cyclopropy1)-methyl)-= N
Propanamide, N-ethenyl-N-[(2-[3-cyclohexen-1-y1]-cyclopropy1)-methyl)-10. N
110 ______________ Propanamide, N-[(2-[3-cyclohexen-1-y1]-cyclopropy1)-methy1]-N-(2-111111, N propeny1)-4I0=
Propanamide, N-[(2-(3-cyclohexen-1--171]-cyclopropy1)-methyl]-N-(cyclopropylmethyl)-= N
410 _______________ Propanamide, N-butyl-N-[(2-[3-' cyclohexen-1-y1]-cyclopropy1)-methyll-= N

Compound # Structure (Novel compounds) CA Index Name 110 _______________________________________________ Propanamide, N-[(2-[3-cyclohexen-1-y1]-cyclopropy1)-methyl]-N-(2-methylpropy1)-o Acetamide, N-[(2-[3-cyclohexen-1-yl]-cyclopropy1)-methyl]-N-methyl-o Acetamide, N-ethyl-N-[(2-[3-cyclohexen-l-y1]-cyclopropy1)-methy1]-o Acetamide, N-[(2-[3-cyclohexen-1-yl]-cyclopropy1)-methy1]-N-propyl-o Acetamide, N-(1-methylethyl)-N-[(2-[3- cyclohexen-1-y1]-cyclopropy1)-methy1]-o Acetamide, N-(1,1-dimethylethyl)-N-[(2-[3- cyclohexen-1-y1]-cyclopropy1)-methy1]-o Acetamide, N-ethenyl-N-[(2-[3-cyclohexen-l-y1]-cyclopropy1)-40 10. N
methyl)-Acetamide, N-[(2-[3-cyclohexeny1]-927 J!
N- cyclopropy1)-methy1]-N-(2-propeny1)-o Acetamide, N-[(2-[3-cyclohexeny1]-cyclopropy1)-methyll-N-(cyclopropylmethyl)-o Acetamide, N-butyl-N-[(2-[3-cyclohexenyl cycloocteny1]-410 1%1.
cyclopropy1)-methy1]-o Acetamide, N-[(2-[3-cyclohexeny1]-cyclopropy1)-methyll-N-(2-410 methylpropy1)-=
Compound # Structure (Novel compounds) CA Index Name Acetamide, N-[(2-[3-cyclohexeny1]-cyclopropy1)-methy1]-N-methyl-1111110. N
410 _____________ Acetamide, N-ethyl-N-[(2-{3-cyclohexeny1]-cyclopropy1)-methyl]-L, 933 ________________ 410 _____________ Acetamide, N-[(2-[3-cyclohexeny1]-cyclopropy1)-methyll-N-propyl-N)L-934 o Acetamide, N-(1-methylethyl)-N-[(2-cyclohexen-1-y11-cyclopropy1)-N
methyl]-110 ______________ Acetamide, N-(1,1-dimethylethyl)-N-[(2-[3- cyclohexen-l-y1]-o cyclopropy1)-methyl]-410 Acetamide, N-ethenyl-N-[(2-[3-cyclohexen-l-yll-cyclopropy1)-Nkmethyl]-' ¨937 Acetamide, N-[(2-[3-cyclohexeny1]-cyclopropy1)-methyl]-N-(2-propeny1)-Nrk 110 _____________ Acetamide, N-[(2-[3-cyclohexeny1]-938 ________________ cyclopropy1)-methyl]-N-(cyclopropylmethyl)-01r- NIA' 110 _____________ Acetamide, N-butyl-N-[(2-[3-cyclohexenyl cycloocteny1]-cyclopropy1)-methy1]-rsrk Compound # Structure (Novel compounds) CA Index Name 010 ________________________________________________ Acetamide, N-[(2-[3-cyclohexen-l-y1]-cyclopropy1)-methyl]-N-(2-o methylpropy1)-_______________________________________________________________________________ ____________________________ 941 Propanamide, N-[(2-[3-cyclohexeny1]-cyclopropy1)-methyl]-N-methy1-2,2-dimethyl-III

943 1,L1 Propanamide, N-ethyl-N-[(2-[3- _____ _ cyclohexen-1-y1]-cyclopropy1)-methy1]-2,2-dimethyl-_______________________________________________________________________________ _________ _ o Propanamide, N-[(2-[3-cyclohexeny1]-cyclopropy1)-methyl]-N-propy1-2,2-dimethyl-_______________________________________________________________________________ _________ _ ______________________________ o Propanamide, N-(1-methylethyl)-N-410 01. N)C( [(2-(3- cyclohexen-1-y1 cyclopropy1)-methy1]-2,2-dimethyl-o Propanamide, N-(1,1-dimethylethyl)--40 I. N)C1 N-[(2-[3-cyclohexeny1]-cyclopropy1)-methy1]-2,2-dimethyl-_______________________________________________________________________________ _________ _ o Propanamide, N-ethenyl-N-[(2-[3-cyclohexen-l-y11-cyclopropy1)-methy1]-2,2-dimethyl-_______________________________________________________________________________ _________ ¨

o Propanamide, N-[(2-[3-NA-I< cyclohexeny1]-cyclopropy1)-methyll-N-(2-propeny1)-2,2-dimethyl-948 joH< Propanamide, N-[(2-[3-cyclohexeny1]-cyclopropy1)-methyl]-N-(cyclopropylmethyl)-2,2-dimethyl-, _______________________________________________________________________________ _______ . o Propanamide, N-butyl-N-[(2-[3-0 ,,N)Li< cyclohexen-l-y1]-cyclopropy1)-methy1]-2,2-dimethyl-/
_950 Propanamide, N-[(2-[3-____________ 011 1 }1 cyclohexeny1]-cyclopropy1)-methyl]-N-(2-methylpropy1)-2,2-dimethyl-951010 4 o Propanamide, N-[(2-[3-cyclohexeny1]-cyclopropy1)-methyl]-NI" N-methy1-2,2-dimethyl-I

, Compound # Structure (Novel compounds) CA Index Name õ,r,,i, ? . Propanamide, N-ethyl-N-[(2-[3-cyclohexen-1-y1]-cyclopropy1)-"S....,,/ methy1]-2,2-dimethyl-) 953 r--1 o Propanamide, N-[(2-[3-cyclohexenyl cycloocteny1]-cyclopropy1)-methyl]-N-propy1-2,2-dimethyl-/
954 4 Propanamide, N-(1-methylethyl)-N-4111 Nl< [(2-[3- cyclohexen-1-y1]-cyclopropy1)-methy11-2,2-dimethyl-/k 955 Propanamide, N-(1,1-dimethylethyl)-Cri ? N-[(2-[3-cycloocteny1]-VX cyclopropy1)-methy11-2,2-dimethyl-...-^\

40 4 o Propanamide, N-ethenyl-N-[(2-(3-cyclonexen-l-y1]-cyclopropy1)-methy1]-2,2-dimethyl--) _______________________________________________________________________________ ____ 410 4 o Propanamide, N-[(2-[3-cyclohexeny1]-cyclopropy1)-methyl]-µ,.....7 )1x N-(2-propeny1)-2,2-dimethyl-Wk< Propanamide, N-[(2-[3-cyclohexeny1]-cyclopropy1)-methyl]-N-(cyclopropylmethyl)-2,2-dimethyl-V') 40 4 o Propanamide, N-butyl-N-[(2-[3-cyclohexen-l-y1]-cyclopropy1)-/N---ily methy1]-2,2-dimethyl-/
960 4 Propanamide, N-[(2-[3-4" Ni< cyclohexenyl]-cyclopropy1)-methyl]-N-(2-methylpropy1)-2,2-dimethyl-7,) o Butanamide, N-[(2-methy1-2-[4-N'j---' methy1-3-penteny1]-cyclopropy1)-I methy1]-N-methy1-2-methyl-,,-o Butanamide, N-ethyl-N-[(2-methy1-2-[4-methy1-3-penteny1]-cyclopropy1)-I / methy1]-2-methyl-o Butanamide, N-[(2-methy1-2-[4-methy1-3-penteny1]-cyclopropy1)-/ / methy1]-N-propy1-2-methyl-Compound # Structure (Novel compounds) CA Index Name 964 o _____________ Butanamide, N-(1-methylethyl)-N--.
[(2-methy1-2-[4-methy1-3-pentenyl]-cyclopropy1)-methy1]-2-methyl-965 o Butanamide, N-(1,1-dimethylethyl)-N-[(2-methy1-2-[4-methy1-3->1 \ penteny1]-cyclopropy1)-methyll-2-methyl-966 o _____________ Butanamide, N-ethenyl-N-[(2-methyl-N), 2-[4-methy1-3-penteny1]-.4") ......." cyclopropy1)-methy1]-2-methyl-967 o Butanamide, N-[(2-methy1-2-[4-methy1-3-penteny1]-cyclopropy1)-r) õ methyll-N-(2-propeny1)-2-methyl-- __________________________________________________________________ 968 , o Butanamide, N-[(2-methyl-2-[4 methy1-3-penteny1]-cyclopropy1)-methyi]-N-(cyclopropylmethyl)-2-V) .- methyl-_ __________________________________________________________________ 969 o Butanamide, N-butyl-N-[(2-methy1-2--.
[4-methy1-3-penteny1]-cyclopropy1)-methy1]-2-methyl-,.., o 970 Butanamide, N-[(2-methy1-2-[4-methy1-3-penteny1]-cyclopropy1)----) methy1]-N-(2-methylpropy1)-2-methyl-. __________________________________________________________________ _ 971 Butanamide, N-[(2-methyl-2-[4 -o methy1-3-penteny1]-cyclopropy1)-methy1]-N-methyl-2-methyl-N, 972 Butanamide, N-ethyl-N-[(2-methy1-2-o [4-methy1-3-penteny1]-cyclopropy1)-methy1]-2-methyl-c' _973 Butanamide, N-[(2-methy1-2-[4-7,)11L o methy1-3-penteny1]-cyclopropy1)-methy1]-N-propy1-2-methyl-_______________________________________________________________________________ _______ ____ 974 Butanamide, N-(1-methylethyl)-N-_______________________________________________________________________________ _________ 1 o [(2-methy1-2-[4-methy1-3-pentenyl]-_______________________________________________________________________________ _________ N,J(õ cyclopropy1)-methy1]-2-methyl-_______________________________________________________________________________ _________ _ =
Compound it Structure (Novel compounds) GA Index Name 975 Butanamide, N-(1,1-dimethylethyl)-o N-[(2-methy1-2-[4-methy1-3-pentenyl]-cyclopropy1)-methyl]-2-976 methyl-Butanamide, N-ethenyl-N-[(2-methyl--, o 2-[4-methy1-3-penteny1]-cyclopropy1)-methy1]-2-methyi-977 Butanamide, N-[(2-methy1-2-[4-o methy1-3-pentenyll-cyclopropy1)-N methy1]-N-(2-propeny1)-2-methyl-978 Butanamide, N-[(2-methy1-2-[4-,A1 methy1-3-pentenyl]-cyclopropy1)-methy1]-N-(cyclopropylmethyl)-2-methyl-979 Butanamide, N-butyl-N-[(2-methy1-2-o [4-methy1-3-penteny1]-cyclopropy1)-methy1]-2-methyl-Butanamide, N-[(2-methy1-2-[4-methyl-3-penteny1]-cyclopropyl)-methy1]-N-(2-methylpropy1)-2-Np4)U
methyl--981 Cyclopropanecarboxamide, m th 1-2-(4-meth 1-3- enten 1]-e Y Y P
Y

cyclopropy1)-methy1]-N-methyl-982 Cyclopropanecarboxamide, N-ethyl-N--, [(2-methyl-2-[4-methy1-3-pentenyl]-iN))/
cyclopropy1)-methy1]-Cyclopropanecarboxamide, N-[(2-methy1-2-[4-methy1-3-pentenyl]-cyclopropy1)-methyll-N-propyl-Cyclopropanecarboxamide, N-(1-methylethyl)-N-[(2-methy1-2-(4-methy1-3-pentenyl]-cyclopropy1)-methy1]-o Cyclopropanecarboxamide, N-(1,1-dimethylethyl) -N- [ (2-methy1-2- [4-methy1-3-pentenyl]-cyclopropy1)-methy1]-Compound # Structure (Novel compounds) CA Index Name 986 Cyclopropanecarboxamide, N-ethenyl-N-[(2-methy1-2-[4-methy1-3-pentenyl]-cyclopropy1)-methy1]-Cyclopropanecarboxamide, N-[(2-methyl-2-[4-methy1-3-pentenyl]-cyclopropy1)-methyl]-N-(2-1 propeny1)-) Cyclopropanecarboxamide, N-[(2-methyl-2-[4-methy1-3-pentenyl]-V, cyclopropy1)-methy1]-N-(cyclopropylmethyl)-Cyclopropanecarboxamide, N-butyl-N-[(2-methy1-2-[4-methy1-3-pentenyl]-)1,1y. cyclopropy1)-methyl]-Cyclopropanecarboxamide, N-[(2-methyl-2-[4-methy1-3-pentenyl]-)Y.
cyclopropy1)-methy1]-N-(2-methylpropy1)-991 Cyclopropanecarboxamide, methy1-2-[4-methy1-3-pentenyl]-cyclopropy1)-methy1]-N-methyl-992 Cyclopropanecarboxamide, N-ethyl-N-[(2-methy1-2-[4-methy1-3-pentenyl]-cyclopropy1)-methyll-\,N -kr/
993Cyclopropanecarboxamide, N-[(2-methyl-2-(4-methyl-3-pentenyl]-cyclopropy1)-methy1]-N-propyl-(N)*
-994 Cyclopropanecarboxamide, N-(1-methylethyl)-N-[(2-methy1-2-[4-methy1-3-penteny1]-cyclopropy1)-N -AT/
methyl]-995 Cyclopropanecarboxamide, N-(1,1-dimethylethyl)-N-[(2-methyl-2-[4-methy1-3-penteny1]-cyclopropy1)-N)Y
methyl)-996 Cyclopropanecarboxamide, N-[(2-methy1-2-[4-methy1-3-pentenyl]-cyclopropy1)-methy1]-, Compound # Structure (Novel compounds) CA Index Name _______________________________________________________________________________ ________ --Cyclopropanecarboxamide, N-[(2-methyl-2-[4-methy1-3-pentenyl]-cyclopropy1)-methy1]-N-(2-N AV
propeny1)-N -IY Cyclopropanecarboxamide, N-[(2-methyl-2-[4-methy1-3-pentenyl]-cyclopropy1)-methy1]-N-T-) (cyclopropylmethyl)-_______________________________________________________________________________ ________ _ Cyclopropanecarboxamide, N-butyl-N-[(2-methy1-2-[4-methy1-3-pentenyl]-cyclopropy1)-methyll-ri ,) .

-j [<
Cyclopropanecarboxamide, N-[(2-methy1-2-(4-methyl-3-pentenyl]-cyclopropy1)-methy1]-N-(2-methylpropy1)-, N
_______________________________________________________________________________ _________ _ o Propanamide, N-[(2-methy1-2-[4-methy1-3-penteny1]-cyclopropy1)-f methy1]-N-methy1-2-methyl-o Propanamide, N-ethyl-N-[(2-methyl-_______________________________________________________________________________ _________ _ \ 2-(4-methy1-3-pentenyll-I cyclopropy1)-methy1]-2-methyl-o Propanamide, N-[(2-methyl-2-[4-N)'L.,,, \ methy1-3-penteny1]-cyclopropy1)-r) methyl)-N-propyl-2-methyl-o Propanamide, N-(1-methylethyl)-N-.

N)C'\ [ (2-methy1-2- [4-methy1-3-penteny1]-1 cyclopropy1)-methy1]-2-methyl-o Propanamide, N-(1,1-dimethylethyl)---.
--7N.--1* N-[(2-methy1-2-[4-methy1-pentenyl]-cyclopropy1)-methy1]-2-methyl-__________________ . ______________________________ o Propanamide, N-ethenyl-N-[(2-\ methy1-2-[4-methy1-3-pentenyl]-.'J cyclopropy1)-methy1]-2-methyl-__________________ . ______________________________ o Propanamide, N-[(2-methy1-2-(4-N)(,/
\ methy1-3-penteny1]-cyclopropy1)-) methy1]-N-(2-propeny1)-2-methyl-Compound # Structure (Novel compounds) CA Index Name _ _ o 1008 Propanamide, N-[(2-methy1-2-[4-,IL,õ.., -..
methyl-3-pentenyl]-cyclopropy1)-V-til I
,methyl]-N-(cyclopropylmethyl)-2-methyl-_______________________________________________________________________________ _________ _ o Propanamide, N-butyl-N-[(2-methyl-N)CV
',. 2-[4-methy1-3-penteny1]-) I cyclopropy1)-methy1]-2-methyl-__________________________________ o Propanamide, N-[(2-methyl-2-[4-_______________________________________________________________________________ _________ _ N'1 methy1-3-penteny1]-cyclopropy1)----1) methyll-N-(2-methylpropy1)-2-methyl-_______________________________________________________________________________ _________ _ , )---'-'-`-'11 N--1."------- Propanamide, N-[(2-methy1-2-[4-methy1-3-1."

-cyclopropyl)-methyll-N-methy1-2-methyl-I
_______________________________________________________________________________ _________ _ Propanamide, N-ethyl-N-[(2-methyl-1_,, 2-(4-methy1-3-pentenyl]-cyclopropy1)-methy1]-2-methyl-C Propanamide, N-[(2-methyl-2--[4-_______________________________________________________________________________ _________ ___ )'<r4L- methyl-3-pentenyl]-cyclopropy1)-methy1]-N-propy1-2-methyl-' __________________ _ Propanamide, N-(1-methylethy1)-N-"NL [(2-methyl-2-[4-methy1-3-pentenyl]-cyclopropy1)-methy1]-2-methyl-,---_______________________________________________________________________________ ____ , WILT' Propanamide, N-(1,1-dimethylethyl)-o N-[(2-methyl-2-[4-methyl-3-pentenyl]-cyclopropy1)-methyl]-2-methyl-, Propanamide, N-ethenyl-N-[(2-methyl-2-[4-methy1-3-pentenyl]-cyclopropy1)-methy1]-2-methyl---) ./1'..J o Propanamide, N-{(2-methyl-2-[4-methyl-3-pentenyl]-cyclopropyl)-methyll-N-(2-propeny1)-2-methyl-,.),JI,T
Propanamide, N-[ (2-methyl-2-[4-1018 methyl-3-pentenyl]-cyclopropyl)-methy1]-N-(cyclopropylmethyl)-2-methyl-Compound # Structure (Novel compounds) CA Index Name _______________________________________________________________________________ _________ , '-L------i< o Propanamide, N-butyl-N-[(2-methyl-2-[4-methy1-3-penteny1]-cyclopropy1)-methy1]-2-methyl-N
,,J
/
_ II Propanamide, N-[(2-methyl-2-[4-methyl-3-pentenyl]-cyclopropyl)-methyl]-N-(2-methylpropy1)-2-N
-) methyl-_ o 2-butenamide, N-[(2-methyl-2-[4-_______________________________________________________________________________ _________ _ , N,JL:7-,, -.. methy1-3-penteny1]-cyclopropy1)-I
methyl] -N-methyl-o ___________________________________________________ 2-butenamide, N-ethyl-N-[(2-methyl-\ 2-[4-methy1-3-penteny1]-I cyclopropy1)-methy1]-o 2-butenamide, N-[(2-methy1-2-(4-N,J(,-,,, \ methy1-3-penteny1]-cyclopropy1)-,--j methy1]-N-propyl-1024 _ __________________________________________________________________ o 2-butenamide, N-(1-methylethyl)-N- _ \ [(2-methy1-2-[4-methy1-3-pentenyl]-cyclopropy1)-methy1]-_______________________________________________________________________________ _______ _ o 2-butenamide, N-(1,1-dimethylethyl)-N-[(2-methyl-2-[4-methyl-3-penteny1]-cyclopropy1)-methyll-.
o 2-butenamide, N-ethenyl-N-[(2-methy1-2-[4-methy1-3-pentenyl]-N
cyclopropy1)-methyl]-___________________ _ __________________________________________________________________ o 2-butenamide, N-[ (2-methyl-2--[4-\ methy1-3-penteny1]-cyclopropy1)-methy1]-N-(2-propeny1)-o 2-butenamide, N-[(2-methy1-2-(4-)1,,, -. methy1-3-penteny1]-cyclopropy1)-N
.7r) methy1]-N-(cyclopropylmethyl)-o 2-butenamide, N-butyl-N-[(2-methyl-2-[4-methy1-3-pentenyl]-N
) cyclopropy1)-methy1]-/

Compound # Structure (Novel compounds) CA Index Name 1030 2-butenamide, N-[(2-methyl-2-[4-N
methyl-3-penteny1]-cyclopropy1)-methy1]-N-(2-methylpropy1)-7 2-butenamide, N-[(2-methy1-2-[4-o methyl-3-pentenyl]-cyclopropy1)-methy1]-N-methyl-2-butenamide, N-ethyl-N-[(2-methyl-o 2-[4-methy1-3-penteny1]-cyclopropy1)-methyl]-(N
2-butenamide, N-[ (2-methyl-2-[4-1033 o methy1-3-penteny1]-cyclopropy1)-methy1]-N-propyl-2-butenamide, N-(1-methylethyl)-N-1034 o [(2-methyl-2-[4-methy1-3-pentenyl]-cyclopropy1)-methyl]-2-butenamide, N-(1,1-o dimethylethyl)-N-[(2-methy1-2-[4-methy1-3-pentenyl3-cyclopropy1)-methyl] -2-butenamide, N-ethenyl-N-[(2-o methyl-2-[4-methy1-3-pentenyl]-cyclopropy1)-methyll-2-butenamide, N-[(2-methyl-2-[4--WAII o methyl-3-penteny1]-cyclopropy1)-methy1]-N-(2-propenyl)-2-butenamide, N-[(2-methy1-2-[4-o methyl-3-penteny1]-cyclopropy1)-methyl]-N-(cyclopropylmethyl)-N
2-butenamide, N-butyl-N-[(2-methy1-2-[4-methyl-3-pentenyl]-cyclopropy1)-methyl]-2-butenamide, N-[(2-methy1-2-[4-o methy1-3-penteny1]-cyclopropy1)-methy1]-N-(2-methylpropyl)-Compound # Structure (Novel compounds) CA Index Name _ o -2-butenamide, N-[(2-methyl-2-[4--,..
methyl-3-penteny1]-cyclopropy1)-I
methyl] -N-methyl-3-methyl-_ o 2-butenamide, N-ethyl-N-[(2-methyl-A-k%<
\ 2-[4-methy1-3-penteny1]-1 cyclopropy1)-methy1]-3-methyl-o 2-butenamide, N-[(2-methy1-2-[4-N-11.,%( \ methy1-3-penteny1]-cyclopropy1)-I methy1]-N-propy1-3-methyl-/
0, 2-butenamide, N-(1-methylethyl)-N-)-I
[(2-methyl-2-[4-methyl-3-pentenyl]-N
..)'.-. cyclopropy1)-methy1]-3-methyl-_ o / 2-butenamide, N-(1,1--, dimethylethyl)-N-[(2-methy1-2-[4-.. methy1-3-penteny1]-cyclopropy1)-methy1]-3-methyl-1_,4, 2-butenamide, N-ethenyl-N-[(2-methy1-2-[4-methy1-3-pentenyl]-N
, cyclopropy1)-methy1]-3-methyl-o 2-butenamide, N-[(2-methy1-2-(4-)1--,%..-, methy1-3-penteny1]-cyclopropy1)-11 methy1]-N-(2-propeny1)-3-methyl-r _ N
-ILI-. 2-butenamide, N-[(2-methyl-2-[4---, methyl-3-penteny1]-cyclopropy1)-I methy1]-N-(cyclopropylmethyl)-3-methyl-, LI-. 2-butenamide, N-butyl-N-[(2-methyl-_ 2-[4-methy1-3-penteny1]-N
.,) cyclopropy1)-methy1]-3-methyl-,---N
-(11. 2-butenamide, N-[(2--methyl-2--[4-methyl-3-penteny1]-cyclopropy1)--,) methyll-N-(2-methylpropy1)-3-methyl-_ 7-L1<
11-LI-. 2-butenamide, N-[(2-methy1-2-[4-methyl-3-penteny1]-cyclopropy1)-methy1]-N-methy1-3-methyl-...
1052 2-butenamide, N-ethyl-N-[(2-methyl-vkriL 9 / 2-[4-methy1-3-penteny11-W)"C. cyclopropy1)-methy1]-3-methyl-C

Compound # Structure (Novel compounds) CA Index Name 1053 2-butenamide, N-[(2-methyl-2-[4-methyl-3-penteny1]-cyclopropy1)-methy1]-N-propy1-3-methyl-1054 2-butenamide, N-(1-methylethyl)-N-[(2-methy1-2-[4-methyl-3-pentenyl]-N cyclopropy1)-methy1]-3-methyl-1055 2-butenamide, N-(1,1-9 / dimethylethyl)-N-[(2-methyl-2-[4-methy1-3-penteny1]-cyclopropy1)-methy1]-3-methyl-2-butenamide, N-ethenyl-N-[(2-methy1-2-[4-methyl-3-pentenyll-cyclopropy1)-methy1]-3-methyl-1057 2-butenamide, N-[(2-methy1-2-[4-9 / methy1-3-penteny1]-cyclopropy1)-N methy1]-N-(2-propeny1)-3-methyl-1058 2-butenamide, N-[(2-methy1-2-[4-9 / methyl-3-penteny1]-cyclopropy1)-methyli-N-(cyclopropylmethyl)-3-methyl-1059 .2-butenamide, N-butyl-N-[(2-methyl-2-[4-methyl-3-penteny1]-cyclopropy1)-methy1]-3-methyl-1060 2-butenamide, N-[(2-methyl-2-[4-methyl-3-penteny1]-cyclopropy1)-methyll-N-(2-methylpropy1)-3-methyl-1061 0 Cyclopropanecarboxamide, N-[(2-[3Z-noneny1]-cyclopropy1)-methyl]-N-methyl 1062 0 Cyclopropanecarboxamide, N-ethyl-N-[(2-[3Z-noneny1]-cyclopropy1)-:4)methyl]-Compound # Structure (Novel compounds) CA Index Name 1063 Cyclopropanecarboxamide, N-[(2-[3Z-noneny1]-cyclopropy1)-methyl]-N-N)17r propyl-0 Cyclopropanecarboxamide, N-(l-methylethyl)-N-[(2-[3Z-nonenyl]-cyclopropy1)-methy1]-/)\
1065 0 Cyclopropanecarboxamide, N-(1,1-41( dimethylethyl)-N-((2-[3Z-nonenyl]-cyclopropy1)-methy1]-A.I7 1066 0 Cyclopropanecarboxamide, N-ethenyl-N-[(2-[3Z-noneny1]-cyclopropy1)-NI1f7methyl] -Cyclopropanecarboxamide, N-[(2-[3Z-nonenyli-cyclopropy1)-methyl3-N-(2-Y.* propeny1)-1068 /\./\ Cyclopropanecarboxamide, N-[(2-[3Z- ' noneny1]-cyclopropy1)-methyl]-N-N AVt (cyclopropylmethyl)-1069 Cyclopropanecarboxamide, N-butyl-N-[(2-[3Z-noneny1]-cyclopropy1)-methyl] -1070 Cyclopropanecarboxamide, N-[(2-[3Z-nonenyl]-cyclopropy1)-methyl]-N-(2-00- methylpropy1)-1071 Cyclopropanecarboxamide, N-[(2-[3Z-44 noneny1]-cyclopropy1)-methyl]-N-O methyl -1072 Cyclopropanecarboxamide, N-ethyl-N-44 [(2-[3Z-noneny1]-cyclopropy1)-o methy1]-:4) Compound # Structure (Novel compounds) CA Index Name -1073 Cyclopropanecarboxamide, N-[(2-[3Z-,, 44 noneny1]-cyclopropy1)-methyl]-N-O propyl-1074 Cyclopropanecarboxamide, N-(1-,, 40 methylethyl)-N-[(2-(3Z-nonenyl]-O cyclopropy1)-methy1]-NJ.L117 1075 Cyclopropanecarboxamide, N-(1,1-,, 44 dimethylethy1)-N-[(2-[3Z-noneny1]-O cyclopropy1)-methy1]-1076 Cyclopropanecarboxamide, N-ethenyl-44 N-[(2-(3Z-nonenyl]-cyclopropy1)-O methyl]-1077 Cyclopropanecarboxamide, N-[(2-[3Z-,, 44 noneny1]-cyclopropy1)-methyl]-N-(2-O propeny1)-1078 Cyclopropanecarboxamide, N-[(2-[3Z-,, 44 noneny1]-cyclopropy1)-methyll-N-O (cyclopropylmethyl)-N)1'',117 -1079 Cyclopropanecarboxamide, N-butyl-N-40 ((2-(3Z-noneny1)-cyclopropy1)-O methyl]-Cyclopropanecarboxamide, N-[(2-[3Z-44 noneny1]-cyclopropy1)-methyl]-N-(2-O methylpropy1)-Compound # Structure (Novel compounds) CA Index Name _______________________________________________________________________________ ___ 410 ' 1111/7 -Cyclopropanecarboxamide, N-[(2-methyl-2-[4methyl-3-cyclohexen-1-y1]-cyclopropy1)-methyll-N-methyl-9 Cyclopropanecarboxamide, N-ethyl-N-N
,K1,1 [(2-methy1-2-[4-methy1-3-cyclohexen-l-y1]-cyclopropy1)-methyl]-3. - Cyclopropanecarboxamide, N-[(2-0 i methyl-2-(4-methyl-3-cyclohexen-1-yll-cyclopropy1)-methy1]-N-propyl-_ _______________________________________________________________________________ ______ , o Cyclopropanecarboxamide, N-(1-methylethyl)-N-[(2-methy1-2-[4.-,)\\methyl-3-cyclohexen-1-y1]-cyclopropy1)-methy1]-o 1085 Cyclopropanecarboxamide, N-(1,1-III '' 41it'17 dimethylethyl)-N-[(2-methyl-2-[4-methyl-3-cyclohexen-l-y1]-cyclopropy1)-methy1]-______________________________________ o Cyclopropanecarboxamide, N-ethenyl-_______________________________________________________________________________ _______ H

Oil j4)LT7 N-[(2--methyl-2-[4-methyl-cyclohexen-1-y1]-cyclopropy1)-methyl]-_______________________________________________________________________________ _______ _ . ____________________________________ o Cyclopropanecarboxamide, N-[(2-Or. N'-7 methy1-2-[4-methy1-3-cyclohexen-1-) y1]-cyclopropy1)-methyl]-N-(2-1 propeny1)-_ o Cyclopropanecarboxamide, N-[(2-IIII methyl-2-[4-methyl-3-cyclohexen-1-y1]-cyclopropy1)-methyll-N-(cyclopropylmethyl)-Cll'' _ o Cyclopropanecarboxamide, N-butyl-N-01089 i 110. N-JV
) [(2-methy1-2-[4-methy1-3-cyclohexen-1-y1)-cyclopropy1)-methyl] -______________________________________ o Cyclopropanecarboxamide, N-[(2-,T,J methy1-2-[4-methy1-3-cyclohexen-I-y1]-cyclopropy1)-methyl]-N-(2-methylpropy1)-, __________________________________________________ 1091 Cyclopropanecarboxamide, N-[(2-010 o methy1-2-[4-methyl-3-cyclohexen-1-y1]-cyclopropyl)-methyl]-N-methyl-r11)7 Compound # Structure (Novel compounds) CA Index Name ¨1092 Cyclopropanecarboxamide, N-ethyl-N-[(2-methy1-2-[4-methyl-3-cyclohexen-l-y1]-cyclopropy1)-methy1]-= NAI7 1093 Cyclopropanecarboxamide, N-[(2-410 methy1-2-[4-methy1-3-cyclohexen-1-yl]-cyclopropy1)-methyll-N-propyl-= w-tyr) 1094 Cyclopropanecarboxamide, N-(1-methylethyl)-N-[(2-methy1-2-[4-methy1-3-cyclohexen-1-y1]-cyclopropy1)-methy1]-= N1)Y
1095 Cyclopropanecarboxamide, N-(1,1-dimethylethyl)-N-[(2-methy1-2-[4-methy1-3-cyclohexen-1-y1]-NAT/ cyclopropy1)-methy1]-1096 1 Cyclopropanecarboxamide, N-ethenyl-0 N-[(2-methy1-2-[4-methy1-cyclohexen-l-y1]-cyclopropy1)-methyll-0 Cyclopropanecarboxamide, N-[(2-methy1-2-[4-methy1-3-cyclohexen-1-yl]-cyclopropy1)-methy1]-N-(2-propeny1)--1098 Cyclopropanecarboxamide, N-[(2-410 methy1-2-(4-methyl-3-cyclohexen-1-yl]-cyclopropy1)-methy1]-N-(cyclopropylmethyl)-Cyclopropanecarboxamide, N-butyl-N-410 [(2-methy1-2-[4-methy1-3-cyclohexen-1-y1]-cyclopropy1)-methy1]-110.
e') Compound # Structure (Novel compounds) CA Index Name 1100 Cyclopropanecarboxamide, N-[(2-410 o methyl-2-[4-methy1-3-cyclohexen-1-y1]-cyclopropy1)-methyl]-N-(2-methylpropy1)-O' Ni)Y
o Cyclopropanecarboxamide, N-[(2,2--'1XMNI)Y dimethyl-cyclopropy1)-methy1]-N-I methyl-- _ ) o Cyclopropanecarboxamide,-N-ethyl-NIY [(2,2-dimethyl-cyclopropy1)-___J methy1]-1103I o ___________ Cyclopropanecarboxamide, N-[(2,2-N'IC17 dimethyl-cyclopropy1)-methy1]-N-) propyl-o Cyclopropanecarboxamide, N-(1-it'17 methylethyl)-N-[(2,2-dimethyl-cyclopropy1)-methyl]-o _______________________________________________________________________________ ______________________ 1105 Cyclopropanecarboxamide, N-(1,1-'1X-M\I)Y dimethylethyl)-N-[(2,2-dimethyl-+ cyclopropy1)-methy1]-_______________________________________________________________________________ _________ _ , __________________ 1106 o ___________ Cyclopropanecarboxamide, N-ethenyl-vIX'N)Y N-[(2,2-dimethyl-cyclopropy1)-,-% methyl]-__________________ _ ______________________________ o 1107 Cyclopropanecarboxamide, N-[(2,2-)I'T/ dimethyl-cyclopropy1)-methy1]-N-(2-,) propeny1)-I
. ___________________________________ o 1108 Cyclopropanecarboxamide, N-[(2,2-dimethyl-cyclopropy1)-methy1]-N-V) (cyclopropylmethyl)-o Cyclopropanecarboxamide, N-butyl-N-[(2,2-dimethyl-cyclopropy1)-J) methyl)-o Cyclopropanecarboxamide, N-[(2,2-dimethyl-cyclopropy1)-methy1]-N-(2-methylpropy1)-_ _________________ 1111 400. Cyclopropanecarboxamide, N-[(2-[2,4-dimethy1-3-cyclohexen-1-y1]-cyclopropy1)-methy1]-N-methyl-Compound # Structure (Novel compounds) CA Index Name _______________________________________________________________________________ ________ _ o Cyclopropanecarboxamide, N-ethyl-N-[(2-[2,4-dimethy1-3-cyclohexen-1-y1]-propy1)-methyl-410 P1 sII/7. Cyclopropanecarboxamide, N-[(2-[2,4-dimethy1-3-cyclohexen-1-y1]-cyclopropy1)-methy1]-N-propyl-/
o Cyclopropanecarboxamide, N-(1-410 1 . 1)--111L17 methylethyl)-N-[(2-[2,4-dimethy1-3-cyclohexen-1-y1]-cyclopropy1)-methyl] -410 li l'7 Cyclopropanecarboxamide, N-(1,1-dimethylethyl)-N-[(2-[2,4-dimethyl-3-cyclohexen-1-y1]-cyclopropy1)-methyl] -(11, , Cyclopropanecarboxamide, N-etheny1-410 ' T-17 N-[(2-(2,4-dimethy1-3-cyclohexen-1-yl]- cyclopropy1)-methyl]-o _ _ __________________________ 0 Cyclopropanecarboxamide, N-[(2-[2,4-dimethy1-3-cyclohexen-1-yl]-propy1)-methyl]-N-(2-propenyl)-I
1118 o Cyclopropanecarboxamide, N-[(2-410 Pz,Y)L/7 [2,4-dimethy1-3-cyclohexen-1-y1]-cyclopropy1)-methy1]-N-(cyclopropylmethyl)-o Cyclopropanecarboxamide, N-butyl-N-[(2-[2,4-dimethy1-3-cyclohexen-1-1119410 0 (JtI7 y1]- cyclopropy1)-methy1]-( o Cyclopropanecarboxamide, N-[(2-N'IY
.'7) [2,4-dimethy1-3-cyclohexen-l-y1]-cyclopropyi)-methyl]-N-(2-methylpropy1)-¨1121 Cyclopropanecarboxamide, N-[(2-110 o [2,4-dimethy1-3-cyclohexen-l-y1]-cyclopropy1)-methy1]-N-methyl--1122 Cyclopropanecarboxamide, N-ethyl-N-010o [(2-[2,4-dimethy1-3-cyclohexen-1-y1]-cyclopropy1)-methyl)-PIO,' N)Ly Compound # Structure (Navel compounds) CA Index Name 1123 Cyclopropanecarboxamide, N-[(2-110 [2,4-dimethy1-3-cyclohexen-1-y1]-cyclopropy1)-methyl)-N-propyl-11111, N )[-17 1124 Cyclopropanecarboxamide, methylethyl)-N-[(2-[2,4-dimethy1-3-cyclohexen-1-y1]-cyclopropy1)-methy1]-Po. m)Y
1125 Cyclopropanecarboxamide, N-(1,1-411 dimethylethyl)-N-[(2-[2,4-dimethyl-3-cyclohexen-1-yl]-cyclopropy1)-methy1]-po. N)LT7 1126 Cyclopropanecarboxamide, N-ethenyl-Oil N-[(2-[2,4-dimethy1-3-cyclohexen-1-y1]- cyclopropy1)-methy1]-OOP. N
1127 1 Cyclopropanecarboxamide, N-[(2-011 [2,4-dimethy1-3-cyclohexen-1-y1]-cyclopropy1)-methy1]-N-(2-propeny1)-111111. N
v) 1128 Cyclopropanecarboxamide, [2,4-dimethy1-3-cyclohexen-1-y1]-cyclopropy1)-methy1]-N-(cyclopropylmethyl)-N )1)7 -1129 Cyclopropanecarboxamide, N-butyl-N-110 [(2-[2,4-dimethy1-3-cyclohexen-1-y1]- cyclopropy1)-methy1]-o N)LT7 1130 Cyclopropanecarboxamide, N-[(2-411 [2,4-dimethy1-3-cyclohexen-1-y1]-cyclopropy1)-methy1]-N-(2-methylpropy1)-NiLT7 Compound # Structure (Novel compounds) CA Index Name 1131 Acetamide, N-[(2-methyl--2--[4-L.
methy1-3-cyclohexen-1-y1]-Nil cyclopropy1)-methy1]-N-methyl-Acetamide, N-ethyl-N-[(2-methy1-2-N
[4-methy1-3-cyclohexen-1-y1]-cyclopropy1)-methyl]-Acetamide, N-[(2-methyl-2-[4-methy1-3-cyclohexen-1-y1]-)1 cyclopropy1)-methy1]-N-propyl-Acetamide, N-(1-methylethyl)-N-[(2-methyl-2-[4-methy1-3-cyclohexen-1-yl]-cyclopropy1)-methyll-o Acetamide, N-(1,1-dimethylethyl)-N.:-[(2-methy1-2-[4-methy1-3-410 00. N
cyclohexen-l-yl]-cyclopropy1)-methy1]-o Acetamide, N-ethenyl-N-[(2-methyl-2-[4-methy1-3-cyclohexen-1-y1]-1137 cyclopropy1)-methy1]-Acetamide, N-[(2-methyl-2-[4-LLõ methy1-3-cyclohexen-l-y11-)4 cyclopropy1)-methy1]-N-(2-propeny1)-Acetamide, N-[(2-methyl--2-[4-methyl-3-cyclohexen-1-y1]-cyclopropy1)-methy1]-N-(cyclopropylmethyl)-Acetamide, N-butyl-N-[(2-methy1-2-[4-methy1-3-cyclohexen-1-y1]-cyclopropy1)-methy1]-Acetamide, N-[(2-methy1-2-[4-methyl-3-cyclohexen-1-y11-cyclopropy1)-methy1]-N-(2-methylpropy1)-1141 Acetamide, N-[(2-methy1-2-[4-410 methy1-3-cyclohexen-1-y1]-cyclopropy1)-methy1]-N-methyl-Nrk =

Compound # Structure (Novel compounds) CA Index Name 1142 Acetamide, N-ethyl-N-[(2-methy1-2-110 [4-methy1-3-cyclohexen-1-y1]-cyclopropy1)-methy1]-1143 Acetamide, N-[(2-methy1-2-[4-110 methy1-3-cyclohexen-1-y1]-cyclopropy1)-methyll-N-propyl-N
1144 Acetamide, N-(1-methylethyl)-N-[(2--, methy1-2-[4-methy1-3-cyclohexen-1-y1]-cyclopropy1)-methyl]-1111. N
1145 Acetamide, N-(1,1-dimethylethyl)-N-010 [(2-methy1-2-[4-methy1-3-cyclohexen-l-y1]-cyclopropy1)-methyl).-1146 Acetamide, N-ethenyl-N-[(2-methyl-410 2-[4-methy1-3-cyclohexen-l-y1]-cyclopropy1)-methy1]-1147 Acetamide, N-[(2-methy1-2-[4--,, methy1-3-cyclohexen-l-y11-cyclopropy1)-methy1]-N-(2-propeny1)-pp-r) 1148 Acetamide, N-[(2-methy1-2-[4-410 0 methy1-3-cyclohexen-l-y1]-cyclopropy1)-methy1]-N-(cyclopropylmethyl)-Compound # Structure (Novel compounds) CA Index Name 1149 Acetamide, N-butyl-N-[(2-methy1-2-410 [4-methy1-3-cyclohexen-1-y1]-cyclopropy1)-methy1]-r 1150 Acetamide, N-[(2-methy1-2-[4-methy1-3-cyclohexen-1-y1]-cyclopropy1)-methy1]-N-(2-methylpropy1)-1151 Acetamide, N-[(2-[2,4-dimethyl-3-cyclohexen-1-y1]-cyclopropyl)-methy1]-N-methyl-o Acetamide, N-ethyl-N-[(2-[2,4-dimethy1-3-cyclohexen-1-y1]-1152 ______________________________________________ 410 10- N) cyclopropy1)-methy1]-o Acetamide, N-[(2-[2,4-dimethy1-3-410 "
cyclohexen-1-y1]-cyclopropy1)-I N?\
methy1]-N-propyl-o Acetamide, N-(1-methylethyl)-N-[(2-' [2,4-dimethy1-3-cyclohexen-l-yl]-410 cyclopropy1)-methy1]-o Acetamide, N-(1,1-dimethylethyl)-N-[(2-(2,4-dimethy1-3-cyclohexen-1-_______________________________________________________________________________ _____ 410 I' >1'11, yll-cyclopropy1)-methyl]-r1156 Acetamide, N-ethenyl-N-[(2-[2,4-dimethy1-3-cyclohexen-1-y1]-cyclopropy1)-methy1]-o Acetamide, N-[(2-[2,4-dimethy1-3-cyclohexen-1-y1]-cyclopropy1)-methyl]-N-(2-propeny1)-o Acetamide, N-[(2-[2,4-dimethy1-3-cyclohexen-1-yll-cyclopropy1)-410 liPrY
methyll-N-(cyclopropylmethyl)-Compound # Structure (Novel compounds) CA Index Name 1159 Acetamide, N-butyl-N-[(2-(2,4-dimethy1-3-cyclohexen-1-y11-cyclopropy1)-methy1]-1160 Acetamide, N-[(2-[2,4-dimethy1-), 410 cyclohexen-1-yl]-cyclopropy1)-methy1]-N-(2-methylpropy1)-1161 Acetamide, N-[(2-[2,4-dimethy1-011 cyclohexen-1-y1]-cyclopropy1)-methyll-N-methyl-N
1162 Acetamide, N-ethyl-N-[(2-[2,4-011 dimethy1-3-cyclohexen-1-y1]-cyclopropy1)-methy1]-1163 Acetamide, N-[(2-[2,4-dimethy1-cyclohexen-1-yll-cyclopropy1)-methy1]-N-propyl-1164 Acetamide, N-(1-methylethyl)-N-[(2-[2,4-dimethy1-3-cyclohexen-l-y1]-cyclopropy1)-methy1]-N
1165 Acetamide, N-(1,1-dimethylethyl)-N-[(2-[2,4-dimethy1-3-cyclohexen-1-yfl-cyclopropy1)-methyll-Nrj*L-1166 Acetamide, N-etheny1-N-[(2-[2,4-110 dimethy1-3-cyclohexen-1-y1]-cyclopropy1)-methy1]-N

Compound # Structure (Novel compounds) CA Index Name 11671 Acetamide, N-[(2-[2,4-dimethy1-3-410 cyclohexen-1-y1]-cyclopropy1)-methy1]-N-(2-propeny1)-N)`

1168 Acetamide, N-[(2-[2,4-dimethy1-110 cyclohexen-1-y1]-cyclopropy1)-methy1]-N-(cyclopropylmethyl)-N
1169 Acetamide, N-buty1-N-[(2-[2,4-110 dimethy1-3-cyclohexen-l-y1]-cyclopropy1)-methy1]-1170 Acetamide, N-[(2-[2,4-dimethy1-410 cyclohexen-l-y1]-cyclopropy1)-methy1]-N-(2-methylpropy1)-1171 Propanamide, N-[(2-[3Z-hexeny1]-cyclopropyl)-methyl]-N-methyl-1172 Propanamide, N-ethyl-N-[(2-[32-hexenyl]-cyclopropy1)-methyl]-1173 Propanamide, N-[(2-[3Z-hexeny1]-cyclopropy1)-methyll-N-propyl-1174 Propanamide, N-(1-methylethyl)-N-[(2-[3Z-hexenyl]-cyclopropy1)-methyl]-Propanamide, N-(1,1-dimethylethyl)-N-[(2-[3Z-hexeny1]-cyclopropy1)-methyl]-Compound # Structure (Novel compounds) CA Index Name Propanamide, N-ethenyl-N-[(2-[3Z-hexenyl]-cyclopropy1)-methyl]-1177 Propanamide, N-[(2-[3Z-hexeny1]-cyclopropy1)-methy1]-N-(2-propeny1)-1178 0 __ / Propanamide, N-[(2-[3Z-hexeny1]-¨\ cyclopropy1)-methy1]-N-(cyclopropylmethyl)-<1( 1179Propanamide, N-butyl-N-[(2-[3Z---\ /-A- N) nexeny1]-cyclopropy1)-methyl]-1180 Propanamide, N-[(2-[3Z-hexenyll-cyclopropy1)-methy1]-N-(2-methylpropy1)-1181 Propanamide, N-[(2-[3Z-hexeny1]-cyclopropy1)-methy1]-N-methyl-1182 Propanamide, N-ethyl-N-[(2-[3Z-/
hexenyl]-cyclopropy1)-methyl]-1183Propanamide, N-[(2-[3Z-hexeny1]-cyclopropy1)-methy1]-N-propyl-Propanamide, N-(1-methylethyl)-N-[(2-[3Z-hexeny1]-cyclopropy1)-methyl] -Propanamide, N-(1,1-dimethylethyl)-__/==\__\v/
N-[(2-[3Z-hexenyll-cyclopropy1)-methyl]-Propanamide, N-ethenyl-N-[(2-[3Z-hexeny1]-cyclopropy1)-methyl]-1187 Propanamide, cyclopropy1)-methy1]-N-(2-propeny1)-Compound # Structure (Novel compounds) CA Index Name 1188 Propanamide, N-[(2-[3Z-hexeny1]-cyclopropy1)-methyll-N-(cyclopropylmethyl)-1189 Propanamide, hexeny1]-cyclopropy1)-methyl]-1190- Propanamide, N-[(2-[3Z-hexeny1]-cyclopropy1)-methyl]-N-(2-methylpropy1)-1191 Acetamide, N-[(2-[3Z-hexeny1]-cyclopropy1)-methyl]-N-methyl-Acetamide, N-ethyl-N-[(2-[3Z-hexenyl]-cyclopropy1)-methy1]-1193 Acetamide, N-[(2-[3Z-hexeny1]-cyclopropy1)-methy1]-N-propyl-Acetamide, N-(1-methylethyl)-N-[(2-[3Z-hexeny1]-cyclopropy1)-methyll--Acetamide, N-(1,1-dimethylethyl)-N-[(2-[3Z-hexeny1]-cyclopropy1)-methyl]-Acetamide, N-ethenyl-N-[(2-[3Z-/Q hexenyl] -cyclopropyl) -methyl] -1197 Acetamide, N-[(2-(3Z-hexeny13-cyclopropy1)-methyl]-N-(2-propeny1)-Acetamide, N-[(2-[3Z-hexeny1]-cyclopropy1)-methy1]-N-(cyclopropylmethyl)-Compound # Structure (Novel compounds) CA Index Name Acetamide, N-butyl-N-[(2-[3Z-hexeny1]-cyclopropyl)-methyl]-q, Acetamide, N-[(2-[3Z-hexenyl]-cyclopropy1)-methy1]-N-(2-methylpropy1)-Acetamide, N-[(2-[3Z-hexeny1]-¨1=-\--V-cyclopropy1)-methy1]-N-methyl-v Acetamide, N-ethyl-N-[(2-[3Z-hexenyl]-cyclopropy1)-methyl]-Acetamide, N-[(2-(3Z-hexeny1]-__/=\__\\7_ cyclopropy1)-methy1]-N-propyl-1204 Acetamide, N-(1-methylethyl)-N-[(2-¨-> [3Z-hexeny1]-cyclopropy1)-methyll-1205¨ Acetamide, N-(1,1-dimethylethyl)-N-[(2-[3Z-hexeny1]-cyclopropy1)-methyl]-1206 Acetamide, N-ethenyl-N-[(2-[3Z-hexenyl]-cyclopropy1)-methy1]-1207 o Acetamide, N-[(2-[3Z-hexeny1]-cyclopropy1)-methy1]-N-(2-propeny1)-o Acetamide, N-((2-(3Z-hexenyl]-cyclopropy1)-methy1]-N-(cyclopropylmethyl)-<j) -1209 Acetamide, hexenyll-cyclopropy1)-methy1]-Compound # Structure (Novel compounds) CA Index Name _______________________________________________________________________________ _________________ _ 1210---1--\7\-- 'c) Acetamide, N-[(2-[3Z-hexeny1]-=\' cyclopropy1)-methyll-N-(2-N methylpropy1)-q 1211 , o 2-butenamide, N-[(2E)-3,7-dimethyl-U _ 2,6-octadieny1]-2-methyl-(2E)--,, H
1212 2-butenamide, N-[(2Z)-3,7-dimethy1-7W 0 2,6-octadieny1]-2-methyl-(2E)-NI,Ay%

- __________________________ o Tide, N-[[2-methyl--2-(4-=7 , H
pentenyl)cyclopropyl]methyl]- _ 1 o Acetamide, N-[[2-methy1-2-(4-1214 1111, Jj= - methyl-3-H pentenyl)cyclopropyl]methy1]-_ o Propanamide, N-[[2-methyl-2--(4-1 N-'t methyl-3-H
pentenyl)cyclopropyl]methyll-___________________________ _ _____________________________ 1216 o Propanamide, N-([2--methyl-2-(4-FNJ methyl-3-pentenyl)cyclopropyl]methy1]-2-methyl-1217 ,--------11:11 N 2-methyl-2-(4-methyl-3-N'''''' pentenyl)Cyclopropanecarboxamide, H
N-cyclopropyl-1218 J<I1 2-methy1-2-(4-methy1-3-pentenyl) Cyclopropanecarboxamide, N-2-H
propenyl-,.....,,,k1 2-methyl-2-(4-methy1-3-pentenyl) Cyclopropanecarboxamide, N-2-H
methylpropanyl-k11,N 2-methy1-2-(4-methy1-3-pentenyl) H
Cyclopropanecarboxamide, N-methyl-1221 2-methy1-2-(4-methy1-3-pentenyl) Cyclopropanecarboxamide, N-ethyl-H

Compound # Structure (Novel compounds) CA Index Name 2-methyl-2-(4-methy1-3-pentenyl) Cyclopropanecarboxamide, N-1-methylethyl-1223 2-methyl-2-(4-methyl-3-pentenyl) Cyclopropanecarboxamide, N-N
cyclopropyl-1224 2-methyl-2-(4-methy1-3-pentenyl) N Cyclopropanecarboxamide, N,N-1 dimethyl-We have surprisingly found the literature has not previously reported dienalkylamides, alkenylamides, or cyclopropylic amides as having or enhancing umami flavor. In addition, closely structurally related compounds such as dienals and unsaturated acids, are not specifically reported to possess umami character when tasted in isolation. In addition the ability to provide an enhanced saltiness for the product without increasing sodium level is not disclosed or suggested by the prior art. The salt enhancing properties of the compounds of the present invention are important because it allows flavorists to provide the desired salty taste profile in foods and beverages without actually having higher salt levels in the food.
Therefore the consumer can have both the taste profile that they desire while without having the adverse health effects associated with increased salt levels such as hypertension.
As used herein olfactory effective amount is understood to mean the amount of compound in flavor compositions the individual component will contribute to its particular olfactory characteristics, but the flavor, taste and aroma effect on the overall composition will be the sum of the effects of each of the flavor ingredients. As used herein taste effects include salt, sweet and umami effects. Thus the compounds of the invention can be used to alter the taste characteristics of the flavor composition by modifying the taste reaction contributed by another ingredient in the composition. The amount will vary depending on many factors including other ingredients, their relative amounts and the effect that is desired.
The level of cyclopropylic amides, alkenylamides and dienalkylamides used in products is greater than 50 parts per billion, generally provided at a level of from about 0.01 parts per million to about 50 parts per million in the finished product, more preferably from about 0.1 parts per million to about 20 parts per million by weight, and in preferred embodiments from about 0.5 to about 5 parts per million.
The usage level of cyclopropylic amides, alkenylamides, and dienalkylamides varies depending on the product in which the dienalkylamides are employed. For example, alcoholic beverages the usage level is from about 0.1 to about 5 parts per million, preferably from about 0.5 to about 3 and most preferably from about 1 to about 2 parts per million by weight. Non-alcoholic beverages are flavored at levels of from about 0.05 parts per million to about 5 parts per million, preferably from about 0.1 parts per billion to about 2 parts per million and in highly preferred situations of from about 0.7 to about 1 parts per billion. Other products such as snack foods, candy and gum products can be advantageously flavored using compounds of the present invention at levels described above.
Among the preferred compounds of the present invention are:
2-butenamide, N-[(2E)-3,7-dimethyl-2,6-octadienyll-, (2E)-2-butenamide, N-[(2Z)-3,7-dimethy1-2,6-octadieny1]-, (2E)-2-butenamide, N-[(2E)-3,7-dimethy1-2,6-octadieny1]-3-methyl-2-butenamide, N-[(2Z)-3,7-dimethy1-2,6-octadieny1]-3-methyl-2-butenamide, N-[(2E)-3,7-dimethy1-2,6-octadieny1]-2-methyl-(2E)-2-butenamide, N-[(2Z)-3,7-dimethy1-2,6-octadieny1]-2-methyl-(2E)-Cyclopropanecarboxamide, N-[(2Z,6Z)-2,6-nonadieny1]-Cyclopropanecarboxamide, N-[(2E,6Z)-2,6-nonadieny1)-Cyclopropanecarboxamide, N-H2E)-3-(3-cyclohexen-l-y1)-2-propeny1)-Cyclopropanecarboxamide, N-[(2E,6Z)-2,6-dodecadieny1]-Cyclopropanecarboxamide, N-[(2E)-3,7-dimethy1-2,6-octadienyl]-Cyclopropanecarboxamide, N-[(2Z)-3,7-dimethy1-2,6-octadieny1]-Propanamide, N-[(2E)-3,7-dimethy1-2,6-octadieny1]- 2-methyl-Propanamide, N-[(2Z)-3,7-dimethy1-2,6-octadieny1]- 2-methyl-Acetamide, N-[(2Z,6Z)-2,6-nonadieny1]-Acetamide, N-[(2E,6Z)-2,6-nonadienyl]-Acetamide, N-[(2Z,6Z)-2-methy1-2,6-nonadieny1]-Acetamide, N-[(2Z,6Z)-2-methyl-2,6-nonadienyl]-Cyclopropanecarboxamide, N-H2-methy1-2-(4-methyl-3-pentenyl)cyclopropyl]methyl]-Acetamide, N-[ f2-methy1-2-(4-methyl-3-pentenyl)cyclopropyl]methyl]-Cyclopropanecarboxamide, N-methyl-N-[(2E,6Z)-2,6-nonadieny1]-Cyclopropanecarboxamide, N-[ (2E)-3,7-dimethyl-2,6-octadienyl]-N-methyl-Cyclopropanecarboxamide, N-[(2E)-3,7-dimethy1-2,6-octadieny1]-N-ethyl-Propanamide, N-[(2E,6Z)-2,6-nonadieny1]-N-cyclopropylmethyl-.
The present invention also provides a method for enhancing or modifying the salt flavor of a food through the incorporation of an organoleptically acceptable level of the compounds described herein. The compounds can be used individually or in combination with other salt enhancing compounds of the present invention. In addition, the salt enhancing materials of the present invention can be used in combination with other salt enhancing compositions known in the art, including those materials listed in co-pending applications US Serial Number 10/919,631 filed on August 17, 2004; US Serial Number 10/861,751 filed on June 4, 2004; and US Serial Number 10/783,652 filed February 20, 2004; and also include cetylpyridium chloride, bretylium tosylate, various polypeptides, mixtures of calcium salts of ascorbic acid, sodium chloride and potassium chloride, as described in various U.S. Patents 4,997,672; 5,288,510; 6,541,050 and U.S.
Patent Application 2003/0091721.
The salt taste enhancing compounds of the present invention may be employed to enhance the perceived salt taste of any salts used in food or beverage products. The preferred salt taste to be enhanced by the compounds of the present invention is that of sodium chloride, primarily because of the discovery that ingestion of large amounts of sodium may have adverse effects on humans and the resultant desirability of reducing salt content while retaining salt taste.
In addition, the compounds of the present invention may also be employed to enhance the perceived salt taste of known salty tasting compounds which may be used as salt substitutes, including potassium chloride and ribonucleotides. Suitable compounds also include cationic amino acids and low molecular weight dipeptides. Specific examples of these compounds are arginine hydrochloride, arginine ammonium chloride, lysine hydrochloride and lysine-ornithine hydrochloride. These compounds exhibit a salty taste but are typically useful only at low concentrations since they exhibit a bitter flavor at higher concentrations. Thus, it is feasible to reduce the sodium chloride content of a food or beverage product by first formulating a food or beverage with less sodium chloride than is necessary to achieve a desired salt taste and then adding to said food or beverage the compounds of the present invention in an amount sufficient to potentiate the salt taste of said salted food or beverage to reach said desired taste.

In addition, the sodium chloride content may be further reduced by substituting a salty-tasting cationic amino acid, a low molecular weight dipeptide or mixtures thereof for at least a portion of the salt.
In a preferred embodiment of the present invention we have found the compound of the present invention are materials used in combination with each other or other salt enhancing materials in weight ratios of from about 1:10 to about 10:1, typically from about 1:3 to about 3:1; more preferably from about 1:1 on a weight basis.
In a highly preferred embodiment we have discovered that the compounds of the present invention when used in combination with the compounds disclosed in co-pending application US Serial Number 10/783,652 filed February 20, 2004. The preferred compounds disclosed in this application include but are not limited to:
N,N,3,7-Tetramethylocta-2,6-dienamide,(2E)-2-propenamide, 3-(3-cyclohexen-1-y1)-N-ethyl-,(2E)-3,7-dimethy1-2,6-octadienamide, N-ethyl-,(2E)-2,6-nonadienamide, N,N-dimethyl-, (2E,6Z)-2,6-nonadienamide, N-cyclopropyl, 2-methyl-, (2E,6Z)-2,6-dodecadienamide, N-ethyl-, (2E,6Z)-2,6-nonadienamide, N-cyclopropyl-, (2E,6Z)-2,6-nonadienamide, N-ethyl-, (2E,6Z)-.
The mixtures of the compounds range from about 1:10 to 10:1 weight percent, preferably from about 1:5 to about 5:1 weight percent, most preferably in a 1:2 to a 2:1 weight ratio of the compounds.
Combinations that have been found to provide high levels of salt and umami enhancing effects to products are compounds of the present invention:

2-butenamide, N-[(2E)-3,7-dimethy1-2,6-octadieny1]-, (2E)-2-butenamide, N-[(2Z)-3,7-dimethy1-2,6-octadieny1]-, (2E)-2-butenamide, N-[(2E)-3,7-dimethy1-2,6-octadieny1]-3-methyl-2-butenamide, N-[(2Z)-3,7-dimethy1-2,6-octadieny1]-3-methyl-2-butenamide, N-[(2E)-3,7-dimethy1-2,6-octadieny1]-2-methyl-(2E)-2-butenamide, N-[(2Z)-3,7-dimethy1-2,6-octadieny1]-2-methy1-(2E)-Cyclopropanecarboxamide, N-[(2Z,6Z)-2,6-nonadieny1]-Cyclopropanecarboxamide, N-[(2E,6Z)-2,6-nonadienyl]-Cyclopropanecarboxamide, N-[(2E)-3-(3-cyclohexen-l-y1)-2-propeny1]-Cyclopropanecarboxamide, N-[(2E,6Z)-2,6-dodecadienyll-Cyclopropanecarboxamide, N-[(2E)-3,7-dimethy1-2,6-octadieny1]-Cyclopropanecarboxamide, N-[(2Z)-3,7-dimethy1-2,6-octadienyl]-Propanamide, N-[(2E)-3,7-dimethy1-2,6-octadieny1]- 2-methyl-Propanamide, N-[(2Z)-3,7-dimethy1-2,6-octadieny1]- 2-methyl-Acetamide, N-[(2Z,6Z)-2,6-nonadieny1]-Acetamide, N-[(2E,6Z)-2,6-nonadieny1]-Acetamide, N-[(2Z,6Z)-2-methy1-2,6-nonadienyl]-Acetamide, N-[(2Z,6Z)-2-methy1-2,6-nonadieny1]-Cyclopropanecarboxamide, N-H2-methy1-2-(4-methyl-3-pentenyl)cyclopropyl]methyl]-Acetamide, N-H2-methy1-2-(4-methyl-3-pentenyl)cyclopropyl]methy1]-Cyclopropanecarboxamide, N-methyl-N-[(2E,6Z)-2,6-nonadieny1]-Cyclopropanecarboxamide, N-[(2E)-3,7-dimethy1-2,6-octadieny1]-N-methyl-Cyclopropanecarboxamide, N-[(2E)-3,7-dimethy1-2,6-octadieny1]-N-ethyl-Propanamide, N-[(2E,6Z)-2,6-nonadieny1]-N-cyclopropylmethyl-N,N,3,7-Tetramethylocta-2,6-dienamide,(2E)-2-propenamide, 3-(3-cyclohexen-l-y1)-N-ethyl-,(2E)-3,7-dimethyl-2,6-octadienamide, N-ethyl-,(2E)-2,6-nonadienamide, N,N-dimethyl-, (2E,6Z)-2,6-nonadienamide, N-cyclopropyl, 2-methyl-, (2E,6Z)-2,6-dodecadienamide, N-ethyl-, (2E,6Z)-2,6-nonadienamide, N-cyclopropyl-, (2E,6Z)-2,6-nonadienamide, N-ethyl-, (2E,6Z)-.
The highly preferred weight ratios of these mixtures is from about 2:1 to about 1:2 on a weight basis. Most highly preferred combination is the mixture of Cyclopropanecarboxamide, N-[(2E)-3,7-dimethy1-2,6-octadienyll- with 2,6-nonadienamide, N-cyclopropyl-, (2E,6Z)- and 2,6-nonadienamide, N-ethyl-, (2E,6Z)-in the ratio about 2:1:1 by weight, with a total use level of 8ppra. For purpose of illustration that would be a usage level of about 4, 2 and 2 parts per million respectively by weight in a product such as a foodstuff.
The term "foodstuff" as used herein includes both solid and liquid ingestible materials for man or animals, which materials usually do, but need not, have nutritional value. Thus, foodstuffs include food products, such as, meats, gravies, soups, convenience foods, malt, alcoholic and other beverages, milk and dairy products, seafood, including fish, crustaceans, mollusks and the like, candies, vegetables, cereals, soft drinks, snacks, dog and cat foods, other veterinary products and the like.
When the compounds of this invention are used in a flavoring composition, they can be combined with conventional flavoring materials or adjuvants. Such co-ingredients or flavor adjuvants are well known in the art for such use and have been extensively described in the literature. Requirements of such adjuvant materials are: (1) that they be non-reactive with the compounds of our invention; (2) that they be organoleptically compatible with the compounds of our invention whereby the flavor of the ultimate consumable material to which the compounds are added is not detrimentally affected by the use of the adjuvant;
and (3) that they be ingestible acceptable and thus nontoxic or otherwise non-deleterious. Apart from these requirements, conventional materials can be used and broadly include other flavor materials, vehicles, stabilizers, thickeners, surface active agents, conditioners and flavor intensifiers.
Such conventional flavoring materials include saturated fatty acids, unsaturated fatty acids and amino acids; alcohols including primary and secondary alcohols, esters, carbonyl compounds including ketones, other than the dienalkylamides of our invention and aldehydes; lactones; other cyclic organic materials including benzene derivatives, acyclic compounds, heterocyclics such as furans, pyridines, pyrazines and the like;
sulfur-containing compounds including thiols, sulfides, disulfides and the like; proteins; lipids, carbohydrates; so-called flavor potentiators such as monosodium glutamate;
magnesium glutamate, calcium glutamate, guanylates and inosinates; natural flavoring materials such as hydrolyzates, cocoa, vanilla and caramel; essential oils and extracts such as anise oil, clove oil and the like and artificial flavoring materials such as vanillin, ethyl vanillin and the like.
Specific preferred flavor adjuvants include but are not limited to the following: anise oil; ethyl-2-methyl butyrate;
vanillin; cis-3-heptenol; cis-3-hexenol; trans-2-heptenal; butyl valerate; 2,3-diethyl pyrazine; methyl cyclo-pentenolone;
benzaldehyde; valerian oil; 3,4-dimethoxy-phenol; amyl acetate;
amyl cinnamate; y-butyryl lactone; furfural; trimethyl pyrazine;
phenyl acetic acid; isovaleraldehyde; ethyl maltol; ethyl vanillin; ethyl valerate; ethyl butyrate; cocoa extract; coffee extract; peppermint oil; spearmint oil; clove oil; anethol;
cardamom oil; wintergreen oil; cinnamic aldehyde; ethyl-2-methyl valerate; y-hexenyl lactone; 2,4-decadienal; 2,4-heptadienal;
methyl thiazole alcohol (4-methyl-5-0-hydroxyethyl thiazole); 2-methyl butanethiol; 4-mercapto-2-butanone; 3-mercapto-2-pentanone; 1-mercapto-2-propane; benzaldehyde; furfural; furfuryl alcohol; 2-mercapto propionic acid; alkyl pyrazine; methyl pyrazine; 2-ethyl-3-methyl pyrazine; tetramethyl pyrazine;
polysulfides; dipropyl disulfide; methyl benzyl disulfide; alkyl thiophene; 2,3-dimethyl thiophene; 5-methyl furfural; acetyl furan; 2,4-decadienal; guiacol; phenyl acetaldehyde; 0-decalactone; d-limonene; acetoin; amyl acetate; maltol; ethyl butyrate; levulinic acid; piperonal; ethyl acetate; n-octanal; n-pentanal; n-hexanal; diacetyl; monosodium glutamate; mono-potassium glutamate; sulfur-containing amino acids, e.g., cysteine; hydrolyzed vegetable protein; 2-methylfuran-3-thiol; 2-methyldihydrofuran-3-thiol; 2,5-dimethylfuran-3-thiol; hydrolyzed fish protein; tetramethyl pyrazine; propylpropenyl disulfide;
propylpropenyl trisulfide; diallyl disulfide; diallyl trisulfide;
dipropenyl disulfide; dipropenyl trisulfide; 4-methyl--2-[ (methyl-thio)-ethyl]-1,3-dithiolane; 4,5-dimethy1-2-(methylthiomethyl)-1,3-dithiolne; and 4-methyl-2-(methylthiomethyl)-1,3-dithiolane.
These and other flavor ingredients are provided in U.S. Patent Nos. 6,110,520 and 6,333,180.
The cyclopropylic amides, alkenylamides, and dienalkylamides of our invention or compositions incorporating them, as mentioned above, can be combined with one or more vehicles or carriers for adding them to the particular product.
Vehicles can be edible or otherwise suitable materials such as ethyl alcohol, propylene glycol, water and the like, as described above. Carriers include materials such as gum arabic, carrageenan, xanthan gum, guar gum and the like.
Cyclopropylic amides, alkenylamides, and dienalkylamides prepared according to our invention can be incorporated with the carriers by conventional means such as spray-drying, extrusion, drum-drying and the like. Such carriers can also include materials for coacervating the dienalkylamides of our invention to provide encapsulated products, as set forth above. When the carrier is an emulsion, the flavoring composition can also contain emulsifiers such as mono- and diglycerides or fatty acids and the like. With these carriers or vehicles, the desired physical form of the compositions can be prepared.
The quantity of cyclopropylic amides, alkenylamides, and dienalkylamides utilized should be sufficient to impart the desired flavor characteristic to the product, but on the other hand, the use of an excessive amount of the compounds is not only wasteful and uneconomical, but in some instances, too large a quantity may unbalance the flavor or other organoleptic properties of the product consumed. The quantity used will vary depending upon the ultimate foodstuff; the amount and type of flavor initially present in the foodstuff; the further process or treatment steps to which the foodstuff will be subjected;
regional and other preference factors; the type of storage, if any, to which the product will be subjected; and the preconsumption treatment such as baking, frying and so on, given to the product by the ultimate consumer. Accordingly, the terminology "organoleptically effective amount" and "sufficient amount" is understood in the context of the present invention to be quantitatively adequate to alter the flavor of the foodstuff.
With reference to the novel compounds of our invention, the synthesis is effected by means of the reaction of acid anhydride with amine, added either directly or in solution, according to the general scheme:

/ Ri0 R5 0 R6) NH2 + R2 where R1, R2, R3, R4, R5 and R6 have the meaning set forth in formula I, and structures 1 and 2 set forth above.

The synthesis of amine follows a literature procedure [The Journal of Organic Chemistry 1989, 54, 3292-3303]. The acid anhydride is dissolved in hexanes to which amine is added in 0.9 to 1.0 equivalent at temperatures ranging 0 C to room temperature, most preferably from 10 C to 20 C. The resulting solution is aged for about 1-3 hours at room temperature.
The reaction can be quenched with aqueous sodium chloride, hydrogen chloride or sodium hydroxide depending upon the need to remove residual acid or amine. The mixture is extracted into ethereal solvent, washed to neutrality and solvent removed.
The crude product is purified by distillation or recrystallization depending on the physical properties. The reaction occurs in 35-70% mole yield based on amine.
In the case when acid anhydride is not readily available, the synthesis is effected by means of the reaction of acid with ethyl chloroformate in the presence of triethylamine and further reaction of the intermediate with amine, added either directly or in solution, according to the general scheme:

0 A -Et Etpl R2 ( OH ________________________________ "" R6 0)Rd where R', R2, R3, R4, R5 and R6 have the meaning set forth in formula I, and structures 1 and 2 set forth above.
The acid is dissolved in dichloromethane to which ethyl chloroformate is added in 1.0 to 2.0 equivalents at temperatures ranging from 0 C to room temperature, most preferably from 10 C to 20 C. The resulting solution is cooled to -10 C to -30 C, and DEMANDES OU BREVETS "VOLUMINEUX
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CECI EST LE TOME ________________________ DE a NOTE: Pour les tomes additionels, veillez contacter le Bureau Canadien des Brevets.
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Claims (23)

1. A compound of the formula:
wherein R7 is selected from the group consisting of H, and methyl R8 is selected from the group consisting of H, and methyl, or R7 and R8 taken together can represent cyclopropyl, or R9 is selected from the group consisting of H and methyl; and R10 is selected from the group consisting of H and methyl.

2. A combination of a consumable material selected from the group consisting of a beverage, a foodstuff, a chewing gum, a dental and oral hygiene product and an organoleptically acceptable level of the compound of claim 1.

3. The combination of claim 2, wherein the organoleptically acceptable level is greater than about 50 parts per billion by weight.

4. The combination of claim 2, wherein the organoleptically acceptable level is from about 0.01 parts per million to about 50 parts per million by weight.

5. A method of enhancing the salty taste of a salt-containing beverage, foodstuff, chewing gum, dental and oral hygiene product comprising the step of adding a salt enhancing level of a compound of the formula:

wherein R7 is selected from the group consisting of H, and methyl R8 is selected from the group consisting of H, and methyl, or R7 and R8 taken together can represent cyclopropyl, or R9 is selected from the group consisting of H and methyl; and R10 is selected from the group consisting of H and methyl

6. A combination of the compound of claim 1 and a foodstuff.

7. A combination comprising (a) the compound of claim 1; and (b) an additional salt taste enhancing material, wherein the weight ratio of (a) to (b) is from about 1 to to from about 10 to 1.

8. The combination of claim 7, wherein the weight ratio of (a) to (b) is from about 1 to 5 to from about 5 to 1.

9. The combination of claim 7, wherein the weight ratio of (a) to (b) is from about 1 to 3 to from about 3 to 1.

10. The combination of claim 7, wherein the compound of claim 1 is selected from the group consisting of:
2-butenamide, N-[(2E)-3,7-dimethyl-2,6-octadienyl]-, (2E)-;
2-butenamide, N-[(2Z)-3,7-dimethyl-2,6-octadienyl]-, (2E)-;
2-butenamide, N-[(2E)-3,7-dimethyl-2,6-octadienyl]-3-methyl-;
2-butenamide, N-[(2Z)-3,7-dimethyl-2,6-octadienyl]-3-methyl-;
Cyclopropanecarboxamide, N-[(2E)-3,7-dimethyl-2,6-octadienyl]-; and Cyclopropanecarboxamide, N-[(2Z)-3,7-dimethyl-2,6-octadienyl]-.

11. A foodstuff or beverage containing the combination of claim 7, wherein the compound of claim 1 is selected from the group consisting of:
2-butenamide, N-[(2E)-3,7-dimethyl-2,6-octadienyl]-, (2E)-;
2-butenamide, N-[(2Z)-3,7-dimethyl-2,6-octadienyl]-, (2E)-;
2-butenamide, N-[(2E)-3,7-dimethyl-2,6-octadienyl]-3-methyl-;
2-butenamide, N-[(2Z)-3,7-dimethyl-2,6-octadienyl]-3-methyl-;
Cyclopropanecarboxamide, N-[(2E)-3,7-dimethyl-2,6-octadienyl]-; and Cyclopropanecarboxamide, N-[(2Z)-3,7-dimethyl-2,6-octadienyl]-.

12. The foodstuff or beverage of claim 11, wherein the additional salt taste enhancing material is selected from the group consisting of N,N,3,7-Tetramethylocta-2,6-dienamide,(2E)-;
2-propenamide, 3-(3-cyclohexen-1-yI)-N-ethyl-,(2E)-;
3,7-dimethyl-2,6-octadienamide, N-ethyl-,(2E)-;
2,6-nonadienamide, N,N-dimethyl-, (2E,6Z)-;
2,6-nonadienamide, N-cyclopropyl, 2-methyl-, (2E,6Z)-;
2,6-dodecadienamide, N-ethyl-, (2E,6Z)-;
2,6-nonadienamide, N-cyclopropyl-, (2E,6Z)-; and 2,6-nonadienamide, N-ethyl-, (2E,6Z)-.

13. A process for augmenting, enhancing or imparting an umami taste to a foodstuff, a chewing gum, a medicinal product, a toothpaste, an alcoholic beverage, an aqueous beverage or a soup comprising the step of adding an organoletically acceptable level of the compound of claim 1.

14. The process of claim 13, wherein organoleptically acceptable level is greater than about 50 parts per billion by weight.

15. A combination of an organoleptically acceptable amount of a compound of the formula:

wherein R7 is selected from the group consisting of H, and methyl R8 is selected from the group consisting of H, and methyl, or R7 and R8 taken together can represent cyclopropyl, or ;
R9 is selected from the group consisting of H and methyl; and R10 is selected from the group consisting of H and methyl and sodium chloride.

16. The combination of claim 15 containing an additional salt substitute compound.

17. The combination of claim 16, wherein the additional salt substitute compound is selected from the group consisting of potassium chloride, ribonucleotides, cationic amino acids, low molecular weight dipeptides, monosodium glutamates and yeasts.

18. The combination of claim 16, wherein the additional salt substitute compound is selected from the group consisting of arginine hydrochloride, arginine ammonium chloride, lysine hydrochloride and lysine-ornithine hydrochloride.

19. The combination of claim 15 provided to a consumable material selected from the group consisting of a foodstuff, a beverage, a chewing gum, a medicinal product, and a toothpaste comprising the combination of claim 15 at a level of greater than about 50 parts per billion by weight.

20. A combination of cyclopropanecarboxamide, N-[(2E)-3,7-dimethyl-2,6-octadienyl]-; 2,6-nonadienamide, N-cyclopropyl-, (2E,6Z)-; and 2,6-nonadienamide, N-ethyl-, (2E,6Z)-.

21. The combination of claim 20, wherein the materials are provided in a weight ratio of cyclopropanecarboxamide, N-[(2E)-3,7-dimethyl-2,6-octadienyl]-; 2,6-nonadienamide, N-cyclopropyl-, (2E,6Z)-; and 2,6-nonadienamide, N-ethyl-, (2E,6Z)-is about 2:1:1.

22. The combination of claim 21 provided to a consumable material selected from the group consisting of a foodstuff, a beverage, a chewing gum, a medicinal product, and a toothpaste.

23. The combination of claim 20 provided to a consumable material selected from the group consisting of a foodstuff, a beverage, a chewing gum, a medicinal product, and a toothpaste at a level greater than about 50 parts per billion by weight.