CA2521634A1 - Drive mechanisms suitable for use in drug delivery devices - Google Patents

Drive mechanisms suitable for use in drug delivery devices Download PDF

Info

Publication number
CA2521634A1
CA2521634A1 CA002521634A CA2521634A CA2521634A1 CA 2521634 A1 CA2521634 A1 CA 2521634A1 CA 002521634 A CA002521634 A CA 002521634A CA 2521634 A CA2521634 A CA 2521634A CA 2521634 A1 CA2521634 A1 CA 2521634A1
Authority
CA
Canada
Prior art keywords
drug delivery
housing
drive mechanism
delivery device
piston rod
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Granted
Application number
CA002521634A
Other languages
French (fr)
Other versions
CA2521634C (en
Inventor
Robert Frederick Veasey
Christopher John Jones
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
DCA Design International Ltd
Original Assignee
Dca Design International Ltd.
Robert Frederick Veasey
Christopher John Jones
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Dca Design International Ltd., Robert Frederick Veasey, Christopher John Jones filed Critical Dca Design International Ltd.
Publication of CA2521634A1 publication Critical patent/CA2521634A1/en
Application granted granted Critical
Publication of CA2521634C publication Critical patent/CA2521634C/en
Anticipated expiration legal-status Critical
Expired - Fee Related legal-status Critical Current

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M5/00—Devices for bringing media into the body in a subcutaneous, intra-vascular or intramuscular way; Accessories therefor, e.g. filling or cleaning devices, arm-rests
    • A61M5/178—Syringes
    • A61M5/31—Details
    • A61M5/315—Pistons; Piston-rods; Guiding, blocking or restricting the movement of the rod or piston; Appliances on the rod for facilitating dosing ; Dosing mechanisms
    • A61M5/31565—Administration mechanisms, i.e. constructional features, modes of administering a dose
    • A61M5/31576—Constructional features or modes of drive mechanisms for piston rods
    • A61M5/31583—Constructional features or modes of drive mechanisms for piston rods based on rotational translation, i.e. movement of piston rod is caused by relative rotation between the user activated actuator and the piston rod
    • A61M5/31585—Constructional features or modes of drive mechanisms for piston rods based on rotational translation, i.e. movement of piston rod is caused by relative rotation between the user activated actuator and the piston rod performed by axially moving actuator, e.g. an injection button
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M5/00—Devices for bringing media into the body in a subcutaneous, intra-vascular or intramuscular way; Accessories therefor, e.g. filling or cleaning devices, arm-rests
    • A61M5/178—Syringes
    • A61M5/31—Details
    • A61M5/315—Pistons; Piston-rods; Guiding, blocking or restricting the movement of the rod or piston; Appliances on the rod for facilitating dosing ; Dosing mechanisms
    • A61M5/31533—Dosing mechanisms, i.e. setting a dose
    • A61M5/31545—Setting modes for dosing
    • A61M5/31548—Mechanically operated dose setting member
    • A61M5/3155—Mechanically operated dose setting member by rotational movement of dose setting member, e.g. during setting or filling of a syringe
    • A61M5/31551—Mechanically operated dose setting member by rotational movement of dose setting member, e.g. during setting or filling of a syringe including axial movement of dose setting member
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M5/00—Devices for bringing media into the body in a subcutaneous, intra-vascular or intramuscular way; Accessories therefor, e.g. filling or cleaning devices, arm-rests
    • A61M5/178—Syringes
    • A61M5/24—Ampoule syringes, i.e. syringes with needle for use in combination with replaceable ampoules or carpules, e.g. automatic
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M5/00—Devices for bringing media into the body in a subcutaneous, intra-vascular or intramuscular way; Accessories therefor, e.g. filling or cleaning devices, arm-rests
    • A61M5/178—Syringes
    • A61M5/31—Details
    • A61M5/315—Pistons; Piston-rods; Guiding, blocking or restricting the movement of the rod or piston; Appliances on the rod for facilitating dosing ; Dosing mechanisms
    • A61M5/31565—Administration mechanisms, i.e. constructional features, modes of administering a dose
    • A61M5/31566—Means improving security or handling thereof
    • A61M5/31573—Accuracy improving means
    • A61M5/31575—Accuracy improving means using scaling up or down transmissions, e.g. gearbox

Abstract

The invention relates to a drive mechanism for use in a drug delivery device comprising an epicyclic gearbox. This drive mechanism can comprise a housing (2) having a helical thread; a piston rod (20) having a non-circular cross section and an external helical thread; a dose dial sleeve (30), which is threadedly engaged with said housing and being rotatable with respect to said housing; a drive sleeve (50), located between said housing and said piston rod, which is threadedly engaged with said piston rod.

Claims (6)

1. A drive mechanism for use is a drug delivery device comprising an epicyclic gearbox, a housing having a helical thread;
a piston rod having a non-circular cross section and an external helical thread;
a dose dial sleeve, which is threadedly engaged with said housing and being rotatable with respect to said housing;
a drive sleeve, located between said housing and said piston rod, which is threadedly engaged with said piston rod.
2. The drive mechanism according to claim 1 characterized in that the said dose dial sleeve is releasibly connected to the said drive sleeve by the said epicyclic gearbox.
3. An assembly for use in a drug delivery device comprising the drive mechanism according to any of claims 1 or 2.
4. A drug delivery device comprising the drive mechanism or the assembly according to any of claims 1 to 3.
5. A method of assembling a drug delivery device comprising the step of providing a drive mechanism or an assembly according to any of claims 1 to 3.
6. The use of a drug delivery device as defined in claim 4 for dispensing a medicinal product comprising an active compound selected from the group consisting of insulin, growth hormone, low molecular weight heparin, their analogues and their derivative.
CA2521634A 2003-04-10 2004-04-08 Drive mechanisms suitable for use in drug delivery devices Expired - Fee Related CA2521634C (en)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
GBGB0308267.4A GB0308267D0 (en) 2003-04-10 2003-04-10 Improvements in and relating to a pen-type injector
GB0308267.4 2003-04-10
PCT/EP2004/003782 WO2004089450A1 (en) 2003-04-10 2004-04-08 Drive mechanisms suitable for use in drug delivery devices

Publications (2)

Publication Number Publication Date
CA2521634A1 true CA2521634A1 (en) 2004-10-21
CA2521634C CA2521634C (en) 2011-11-22

Family

ID=9956535

Family Applications (1)

Application Number Title Priority Date Filing Date
CA2521634A Expired - Fee Related CA2521634C (en) 2003-04-10 2004-04-08 Drive mechanisms suitable for use in drug delivery devices

Country Status (11)

Country Link
US (1) US7918832B2 (en)
EP (1) EP1615686A1 (en)
JP (1) JP4847858B2 (en)
AR (1) AR043842A1 (en)
AU (1) AU2004228940B2 (en)
CA (1) CA2521634C (en)
GB (1) GB0308267D0 (en)
IL (1) IL171247A (en)
MX (1) MXPA05010623A (en)
TW (1) TWI322017B (en)
WO (1) WO2004089450A1 (en)

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WO2004089450A1 (en) 2004-10-21
US20050004529A1 (en) 2005-01-06
AR043842A1 (en) 2005-08-17
MXPA05010623A (en) 2005-12-12
CA2521634C (en) 2011-11-22
EP1615686A1 (en) 2006-01-18
TW200507898A (en) 2005-03-01
GB0308267D0 (en) 2003-05-14
IL171247A (en) 2012-08-30
AU2004228940A1 (en) 2004-10-21
JP4847858B2 (en) 2011-12-28
US7918832B2 (en) 2011-04-05
AU2004228940B2 (en) 2010-09-30
JP2006522630A (en) 2006-10-05
TWI322017B (en) 2010-03-21

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