CA2526848C - Endoluminal device having enhanced affixation characteristics - Google Patents

Endoluminal device having enhanced affixation characteristics Download PDF

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Publication number
CA2526848C
CA2526848C CA2526848A CA2526848A CA2526848C CA 2526848 C CA2526848 C CA 2526848C CA 2526848 A CA2526848 A CA 2526848A CA 2526848 A CA2526848 A CA 2526848A CA 2526848 C CA2526848 C CA 2526848C
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Prior art keywords
neck
endograft
shoulder
region
diameter
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Expired - Fee Related
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CA2526848A
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French (fr)
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CA2526848A1 (en
Inventor
Christopher J. Elliott
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Boston Scientific Ltd Barbados
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Boston Scientific Ltd Barbados
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Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61F—FILTERS IMPLANTABLE INTO BLOOD VESSELS; PROSTHESES; DEVICES PROVIDING PATENCY TO, OR PREVENTING COLLAPSING OF, TUBULAR STRUCTURES OF THE BODY, e.g. STENTS; ORTHOPAEDIC, NURSING OR CONTRACEPTIVE DEVICES; FOMENTATION; TREATMENT OR PROTECTION OF EYES OR EARS; BANDAGES, DRESSINGS OR ABSORBENT PADS; FIRST-AID KITS
    • A61F2/00—Filters implantable into blood vessels; Prostheses, i.e. artificial substitutes or replacements for parts of the body; Appliances for connecting them with the body; Devices providing patency to, or preventing collapsing of, tubular structures of the body, e.g. stents
    • A61F2/82—Devices providing patency to, or preventing collapsing of, tubular structures of the body, e.g. stents
    • A61F2/86—Stents in a form characterised by the wire-like elements; Stents in the form characterised by a net-like or mesh-like structure
    • A61F2/90—Stents in a form characterised by the wire-like elements; Stents in the form characterised by a net-like or mesh-like structure characterised by a net-like or mesh-like structure
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61F—FILTERS IMPLANTABLE INTO BLOOD VESSELS; PROSTHESES; DEVICES PROVIDING PATENCY TO, OR PREVENTING COLLAPSING OF, TUBULAR STRUCTURES OF THE BODY, e.g. STENTS; ORTHOPAEDIC, NURSING OR CONTRACEPTIVE DEVICES; FOMENTATION; TREATMENT OR PROTECTION OF EYES OR EARS; BANDAGES, DRESSINGS OR ABSORBENT PADS; FIRST-AID KITS
    • A61F2/00—Filters implantable into blood vessels; Prostheses, i.e. artificial substitutes or replacements for parts of the body; Appliances for connecting them with the body; Devices providing patency to, or preventing collapsing of, tubular structures of the body, e.g. stents
    • A61F2/02—Prostheses implantable into the body
    • A61F2/04—Hollow or tubular parts of organs, e.g. bladders, tracheae, bronchi or bile ducts
    • A61F2/06—Blood vessels
    • A61F2/07—Stent-grafts
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61F—FILTERS IMPLANTABLE INTO BLOOD VESSELS; PROSTHESES; DEVICES PROVIDING PATENCY TO, OR PREVENTING COLLAPSING OF, TUBULAR STRUCTURES OF THE BODY, e.g. STENTS; ORTHOPAEDIC, NURSING OR CONTRACEPTIVE DEVICES; FOMENTATION; TREATMENT OR PROTECTION OF EYES OR EARS; BANDAGES, DRESSINGS OR ABSORBENT PADS; FIRST-AID KITS
    • A61F2/00—Filters implantable into blood vessels; Prostheses, i.e. artificial substitutes or replacements for parts of the body; Appliances for connecting them with the body; Devices providing patency to, or preventing collapsing of, tubular structures of the body, e.g. stents
    • A61F2/82—Devices providing patency to, or preventing collapsing of, tubular structures of the body, e.g. stents
    • A61F2/848—Devices providing patency to, or preventing collapsing of, tubular structures of the body, e.g. stents having means for fixation to the vessel wall, e.g. barbs
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61F—FILTERS IMPLANTABLE INTO BLOOD VESSELS; PROSTHESES; DEVICES PROVIDING PATENCY TO, OR PREVENTING COLLAPSING OF, TUBULAR STRUCTURES OF THE BODY, e.g. STENTS; ORTHOPAEDIC, NURSING OR CONTRACEPTIVE DEVICES; FOMENTATION; TREATMENT OR PROTECTION OF EYES OR EARS; BANDAGES, DRESSINGS OR ABSORBENT PADS; FIRST-AID KITS
    • A61F2/00—Filters implantable into blood vessels; Prostheses, i.e. artificial substitutes or replacements for parts of the body; Appliances for connecting them with the body; Devices providing patency to, or preventing collapsing of, tubular structures of the body, e.g. stents
    • A61F2/02—Prostheses implantable into the body
    • A61F2/04—Hollow or tubular parts of organs, e.g. bladders, tracheae, bronchi or bile ducts
    • A61F2/06—Blood vessels
    • A61F2002/065—Y-shaped blood vessels
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61F—FILTERS IMPLANTABLE INTO BLOOD VESSELS; PROSTHESES; DEVICES PROVIDING PATENCY TO, OR PREVENTING COLLAPSING OF, TUBULAR STRUCTURES OF THE BODY, e.g. STENTS; ORTHOPAEDIC, NURSING OR CONTRACEPTIVE DEVICES; FOMENTATION; TREATMENT OR PROTECTION OF EYES OR EARS; BANDAGES, DRESSINGS OR ABSORBENT PADS; FIRST-AID KITS
    • A61F2/00—Filters implantable into blood vessels; Prostheses, i.e. artificial substitutes or replacements for parts of the body; Appliances for connecting them with the body; Devices providing patency to, or preventing collapsing of, tubular structures of the body, e.g. stents
    • A61F2/02—Prostheses implantable into the body
    • A61F2/04—Hollow or tubular parts of organs, e.g. bladders, tracheae, bronchi or bile ducts
    • A61F2/06—Blood vessels
    • A61F2/07—Stent-grafts
    • A61F2002/077—Stent-grafts having means to fill the space between stent-graft and aneurysm wall, e.g. a sleeve
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61F—FILTERS IMPLANTABLE INTO BLOOD VESSELS; PROSTHESES; DEVICES PROVIDING PATENCY TO, OR PREVENTING COLLAPSING OF, TUBULAR STRUCTURES OF THE BODY, e.g. STENTS; ORTHOPAEDIC, NURSING OR CONTRACEPTIVE DEVICES; FOMENTATION; TREATMENT OR PROTECTION OF EYES OR EARS; BANDAGES, DRESSINGS OR ABSORBENT PADS; FIRST-AID KITS
    • A61F2220/00—Fixations or connections for prostheses classified in groups A61F2/00 - A61F2/26 or A61F2/82 or A61F9/00 or A61F11/00 or subgroups thereof
    • A61F2220/0008—Fixation appliances for connecting prostheses to the body
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61F—FILTERS IMPLANTABLE INTO BLOOD VESSELS; PROSTHESES; DEVICES PROVIDING PATENCY TO, OR PREVENTING COLLAPSING OF, TUBULAR STRUCTURES OF THE BODY, e.g. STENTS; ORTHOPAEDIC, NURSING OR CONTRACEPTIVE DEVICES; FOMENTATION; TREATMENT OR PROTECTION OF EYES OR EARS; BANDAGES, DRESSINGS OR ABSORBENT PADS; FIRST-AID KITS
    • A61F2220/00—Fixations or connections for prostheses classified in groups A61F2/00 - A61F2/26 or A61F2/82 or A61F9/00 or A61F11/00 or subgroups thereof
    • A61F2220/0008—Fixation appliances for connecting prostheses to the body
    • A61F2220/0016—Fixation appliances for connecting prostheses to the body with sharp anchoring protrusions, e.g. barbs, pins, spikes
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61F—FILTERS IMPLANTABLE INTO BLOOD VESSELS; PROSTHESES; DEVICES PROVIDING PATENCY TO, OR PREVENTING COLLAPSING OF, TUBULAR STRUCTURES OF THE BODY, e.g. STENTS; ORTHOPAEDIC, NURSING OR CONTRACEPTIVE DEVICES; FOMENTATION; TREATMENT OR PROTECTION OF EYES OR EARS; BANDAGES, DRESSINGS OR ABSORBENT PADS; FIRST-AID KITS
    • A61F2230/00—Geometry of prostheses classified in groups A61F2/00 - A61F2/26 or A61F2/82 or A61F9/00 or A61F11/00 or subgroups thereof
    • A61F2230/0002—Two-dimensional shapes, e.g. cross-sections
    • A61F2230/0028—Shapes in the form of latin or greek characters
    • A61F2230/0054—V-shaped
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61F—FILTERS IMPLANTABLE INTO BLOOD VESSELS; PROSTHESES; DEVICES PROVIDING PATENCY TO, OR PREVENTING COLLAPSING OF, TUBULAR STRUCTURES OF THE BODY, e.g. STENTS; ORTHOPAEDIC, NURSING OR CONTRACEPTIVE DEVICES; FOMENTATION; TREATMENT OR PROTECTION OF EYES OR EARS; BANDAGES, DRESSINGS OR ABSORBENT PADS; FIRST-AID KITS
    • A61F2230/00—Geometry of prostheses classified in groups A61F2/00 - A61F2/26 or A61F2/82 or A61F9/00 or A61F11/00 or subgroups thereof
    • A61F2230/0063—Three-dimensional shapes
    • A61F2230/0071—Three-dimensional shapes spherical
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61F—FILTERS IMPLANTABLE INTO BLOOD VESSELS; PROSTHESES; DEVICES PROVIDING PATENCY TO, OR PREVENTING COLLAPSING OF, TUBULAR STRUCTURES OF THE BODY, e.g. STENTS; ORTHOPAEDIC, NURSING OR CONTRACEPTIVE DEVICES; FOMENTATION; TREATMENT OR PROTECTION OF EYES OR EARS; BANDAGES, DRESSINGS OR ABSORBENT PADS; FIRST-AID KITS
    • A61F2230/00—Geometry of prostheses classified in groups A61F2/00 - A61F2/26 or A61F2/82 or A61F9/00 or A61F11/00 or subgroups thereof
    • A61F2230/0063—Three-dimensional shapes
    • A61F2230/0073—Quadric-shaped
    • A61F2230/0076—Quadric-shaped ellipsoidal or ovoid
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61F—FILTERS IMPLANTABLE INTO BLOOD VESSELS; PROSTHESES; DEVICES PROVIDING PATENCY TO, OR PREVENTING COLLAPSING OF, TUBULAR STRUCTURES OF THE BODY, e.g. STENTS; ORTHOPAEDIC, NURSING OR CONTRACEPTIVE DEVICES; FOMENTATION; TREATMENT OR PROTECTION OF EYES OR EARS; BANDAGES, DRESSINGS OR ABSORBENT PADS; FIRST-AID KITS
    • A61F2230/00—Geometry of prostheses classified in groups A61F2/00 - A61F2/26 or A61F2/82 or A61F9/00 or A61F11/00 or subgroups thereof
    • A61F2230/0063—Three-dimensional shapes
    • A61F2230/0073—Quadric-shaped
    • A61F2230/008—Quadric-shaped paraboloidal
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61F—FILTERS IMPLANTABLE INTO BLOOD VESSELS; PROSTHESES; DEVICES PROVIDING PATENCY TO, OR PREVENTING COLLAPSING OF, TUBULAR STRUCTURES OF THE BODY, e.g. STENTS; ORTHOPAEDIC, NURSING OR CONTRACEPTIVE DEVICES; FOMENTATION; TREATMENT OR PROTECTION OF EYES OR EARS; BANDAGES, DRESSINGS OR ABSORBENT PADS; FIRST-AID KITS
    • A61F2250/00—Special features of prostheses classified in groups A61F2/00 - A61F2/26 or A61F2/82 or A61F9/00 or A61F11/00 or subgroups thereof
    • A61F2250/0014—Special features of prostheses classified in groups A61F2/00 - A61F2/26 or A61F2/82 or A61F9/00 or A61F11/00 or subgroups thereof having different values of a given property or geometrical feature, e.g. mechanical property or material property, at different locations within the same prosthesis
    • A61F2250/0039—Special features of prostheses classified in groups A61F2/00 - A61F2/26 or A61F2/82 or A61F9/00 or A61F11/00 or subgroups thereof having different values of a given property or geometrical feature, e.g. mechanical property or material property, at different locations within the same prosthesis differing in diameter

Abstract

An endoluminal device (30) for affixation to a wall of a body lumen (32) having a neck region (36) defined by a relatively narrow width and a shoulder region (38) that diverges from the neck region to a relatively wider width.
The device comprises a shoulder portion (46), which may be part of a bulbous portion, having a diameter profile that conforms to the shoulder region, and, in some embodiments, a plurality of affixation members (42) in an area of the device that typically extends from a distal end (16) of the device (30) through the shoulder portion (46). In one embodiment, the device comprises an endograft (52) for repair of an aneurysm, such as an abdominal aortic aneurysm (AAA). Methods of using the endograft (52) to inhibit continued diametric expansion of the aneurysm and to inhibit endoleak formation and migration of the endograft are also described.

Claims (41)

1. An endoluminal device for affixation to a wall of a body lumen, the body lumen characterized by a diameter profile having a neck region defined by a relatively narrow width and a shoulder region that diverges from the neck region to a relatively wider width, the device comprising:

a neck having a diameter approximately equal to the lumen neck region width;

a shoulder portion adjacent to the neck having a device diameter profile that conforms to a lumen diameter profile of the shoulder region for deployment in the shoulder region;

a bulbous portion, wherein the shoulder portion comprises a part of the bulbous portion and the neck is adjacent the bulbous portion, and wherein the bulbous portion has a length characterized by a diverging and converging diameter greater than the neck diameter along the bulbous portion length and the bulbous portion has a diameter profile in the converging part of the bulbous portion length that does not conform to the body lumen diameter profile.
2. The endoluminal device of claim 1, wherein the device comprises a compressed configuration and a radially expanded configuration, the device neck having a first radial self-expansion force and the shoulder portion having a second radial self-expansion force less than the first radial expansion force.
3. The endoluminal device of claim 1, wherein the bulbous portion of the device comprises a stent having at least one superelastic section and at least one plastically deformable section.
4. The endoluminal device of claim 1 further comprising a plurality of affixation members at least on part of the shoulder portion.
5. The endoluminal device of claim 4, wherein the affixation members comprise hooks, barbs, or other members that project radially outward from the device.
6. The endoluminal device of claim 4, wherein the device has a distal end adapted to be positioned in an upstream portion of the lumen and the plurality of affixation members are disposed in an area of the device extending proximally from the distal end of the device through the shoulder portion.
7. The endoluminal device of claim 6, wherein the area in which the plurality of affixation members are disposed extends axially to a maximum diameter portion of the shoulder portion.
8. The endoluminal device of claim 1, wherein the device comprises a stent.
9. The endoluminal device of claim 8, wherein the stent comprises at least one superelastic section and at least one plastically deformable section.
10. The endoluminal device of claim 1, wherein the shoulder portion of the device comprises a stent having at least one superelastic section and at least one plastically deformable section.
11. The endoluminal device of claim 1, wherein the device comprises an endograft comprising a stent that is at least partially covered or lined with a graft material.
12. The endoluminal device of claim 11, wherein the endograft is adapted to repair an aneurysm.
13. The endoluminal device of claim 12, wherein the endograft is adapted to repair an abdominal aortic aneurysm (AAA).
14. The endoluminal device of claim 13, wherein the neck region includes a renal neck at a distal end of the aneurysm and the shoulder portion is adapted to be proximal the renal neck at the shoulder region.
15. The endoluminal device of claim 13, wherein the neck region includes an iliac neck at a proximal end of the aneurysm and the shoulder portion is adapted to be distally of the iliac neck.
16. An endoluminal device adapted to repair an abdominal aortic aneurysm (AAA) for affixation to a wall of a body lumen, the body lumen characterized by a diameter profile having a renal neck region, defined by a relatively narrow width, and a renal shoulder region that diverges from the renal neck region at a distal end of the aneurysm and an iliac neck region, defined by a relatively narrow width, and an iliac shoulder region that diverges from the iliac neck region at a proximal end of the aneurysm, the device comprising:

a distal shoulder portion having a diameter profile that conforms to the renal shoulder region for deployment in the renal shoulder region;

one or more proximal shoulder portions each for deployment in the iliac shoulder region, each proximal shoulder portion having a diameter profile that conforms to the corresponding iliac shoulder region; and one or more bulbous portions, wherein the one or more shoulder portions comprise a part of the one or more bulbous portions, wherein the one or more bulbous portions each have a length characterized by a diverging and converging diameter greater than an adjacent renal neck region or an adjacent iliac neck region along the bulbous portion length and the one or more bulbous portions each have a diameter profile in the converging part of the bulbous portion length that does not conform to the profile of the aneurysm as the profile diverges from the adjacent renal neck region or the adjacent iliac neck region.
17. The device of claim 16, further comprising a plurality of affixation members at least on part of the distal shoulder portion and on part of the one or more proximal shoulder portions.
18. The device of claim 17, wherein the distal shoulder portion is part of a distal bulbous portion and each of the one or more proximal shoulder portions are part of a corresponding proximal bulbous portion.
19. The endoluminal device of claim 16, wherein the distal shoulder portion and the one or more proximal shoulder portions comprise a non-modular device.
20. The endoluminal device of claim 16, wherein the distal shoulder portion and the one or more proximal shoulder portions comprise a modular device.
21. The endoluminal device of claim 20, wherein a first modular component comprises the distal shoulder portion and a first proximal shoulder portion, and a second modular component comprises a second proximal shoulder portion.
22. An endograft for repair of an abdominal aortic aneurysm (AAA) having a lumen wall, the endograft comprising a stent at least partially lined or covered by a graft material and having a distal end comprising a distal neck having a first diameter and a first bulbous portion located proximally of the distal neck and having a proximally diverging then converging diameter greater than the first diameter, at least the distal neck and part of the first bulbous portion comprising a plurality of affixation members that project radially outward from the device for affixation to the lumen wall of the AAA, wherein the distal neck is adjacent the bulbous portion, and wherein the bulbous portion has a diameter profile in the converging part of the bulbous portion length that does not conform to a diameter profile of the AAA.
23. The endograft of claim 22, wherein the plurality of affixation members are disposed in an area that extends axially from a distal end of the endograft to at least an intermediate location in the first bulbous portion.
24. The endograft of claim 23, wherein the area in which the plurality of affixation members are disposed extends axially to a maximum diameter portion of the first bulbous portion.
25. The endograft of claim 22 having a compressed configuration and a radially expanded configuration, the device neck having a first radial self-expansion force and the first bulbous portion having a second radial self-expansion force less than the first radial self-expansion force.
26. The endograft of claim 22 further comprising a proximal end comprising at least one proximal neck having a second diameter and an additional corresponding bulbous portion located distally of the proximal neck and having a distally diverging then converging diameter greater than the second diameter, at least the proximal neck and part of the additional corresponding bulbous portion comprising a plurality of affixation members that project radially outward from the device for affixation to the lumen wall of the AAA.
27. The endograft of claim 26 comprising:

two proximal necks and two additional corresponding bulbous portions; and each proximal neck and additional corresponding bulbous portion for deployment adjacent an iliac neck region of the AAA, wherein each distal neck is adjacent the corresponding bulbous portion, and wherein the corresponding bulbous portion has a diameter profile in the converging part of the bulbous portion length that does not conform to the diameter profile of the AAA.
28. The endograft of claim 26, wherein the distal neck and first bulbous portion comprise a first modular component and the proximal neck and additional corresponding bulbous portion comprises a second modular component.
29. The endograft of claim 27, wherein the distal neck and first bulbous portion comprise a first modular component, and each proximal neck and additional corresponding bulbous portion comprise additional modular components.
30. The endograft of claim 27, wherein the distal neck, first bulbous portion, one proximal neck, and one additional corresponding bulbous portion comprise a first modular component, and another proximal neck and additional corresponding bulbous portion comprise a second modular component.
31. Use of an endograft for inhibition of diametric expansion of an aneurysm having a lumen wall, the aneurysm characterized by a diameter profile having an aneurysm neck region at one end having a width and a shoulder region adjacent the neck region having a diverging width greater than the width of the aneurysm neck region, wherein the endograft comprises:

an endograft neck with a diameter approximately equal to the width of the aneurysm neck region; and a shoulder portion having a device diameter profile that conforms to a lumen diameter profile of the shoulder region of the aneurysm, wherein the shoulder portion comprises part of a bulbous portion that is located adjacent the endograft neck and wherein the bulbous portion has a length characterized by a diverging and converging diameter greater than the endograft neck diameter along the bulbous portion length, the endograft having a diameter profile in the converging diameter part of the bulbous portion length that does not conform to the aneurysm diameter profile, the endograft neck and the shoulder portion comprising a plurality of affixation members for affixing to the lumen wall of the aneurysm.
32. Use of an endograft for inhibition of endoleak formation and migration of a further endograft deployed in a lumen characterized by a diameter profile having a lumen wall, a lumen neck region having a lumen neck width, and a lumen shoulder region adjacent the lumen neck region having a diverging width greater than the lumen neck region width, wherein the endograft comprises:

an endograft neck having a diameter approximately equal to the lumen neck region diameter; and a shoulder portion adapted to match the diverging width of the lumen shoulder region, wherein the shoulder portion comprises part of a bulbous portion, and the endograft neck is located adjacent the bulbous portion, wherein the bulbous portion has a length characterized by a diverging and converging diameter greater than the endograft neck diameter along the bulbous portion length, the endograft having a diameter profile in the converging part of the bulbous portion length that does not conform to the lumen diameter profile.
33. The use of claim 32, wherein the endograft neck and the shoulder portion further comprise a plurality of affixation members suitable for affixing to the lumen wall.
34. Use of an endograft for reparation of a body lumen characterized by a diameter profile having a lumen wall, a lumen neck region having a lumen neck width, and a lumen shoulder region proximal the lumen neck region having a diverging width greater than the lumen neck region width, wherein the endograft has an expanded configuration and a compressed configuration, the endograft comprises in the expanded configuration an endograft neck with a diameter approximately equal to the lumen neck region width and a bulbous portion having a shoulder region adapted to match the diverging width of the lumen shoulder region, wherein the bulbous portion has a length characterized by a diverging and converging diameter greater than the endograft neck diameter along the bulbous length, the endograft has a diameter profile in the converging diameter part of the bulbous length that does not conform to the lumen diameter profile;

the endograft further comprising a plurality of affixation members suitable for affixing to the lumen wall, the affixation members being disposed along an axial region of the endograft including at least the endograft neck and the shoulder portion of the bulbous portion;

wherein in the compressed configuration, the endograft is suitable for introduction into the body lumen to a deployment location; and wherein in the expanded configuration, the endograft shoulder portion is adapted for alignment with the lumen shoulder region and one or ore of the affixation members in the endograft neck are suitable for affixing to the lumen neck region and one or more of the affixation members in the endograft shoulder portion are suitable for affixing to at least a portion of the lumen shoulder region.
35. The use of claim 34, wherein the endograft is for reparation of an aneurysm.
36. The use of claim 34, wherein the endograft is for reparation of an abdominal aortic aneurysm.
37. The use of claim 35, wherein the endograft further comprises a self-expanding stent having at least a partial covering or lining of a graft material, the self-expanding stent self-expands from the compressed configuration to the expanded configuration.
38. The use of claim 37, wherein, in the expanded configuration, the stent is adapted for exerting a radial expansion force against the lumen wall, wherein the radial expansion force exerted by the endograft neck is greater than the radial expansion force exerted by the bulbous portion.
39. The use of claim 37, wherein the endograft comprises a combination self-expanding/plastically-deformable stent suitable for modeling the stent in the expanded configuration to conform to the lumen wall.
40. Use of an endograft for reparation of an abdominal aortic aneurysm (AAA) in a body lumen characterized by a diameter profile having a lumen wall, the body lumen having, at a distal end of the AAA, a renal neck region, defined by a relatively narrow width, and a renal shoulder region that diverges from the renal neck region;
and, at a proximal end of the AAA, one or more iliac neck regions defined by a relatively narrow width, and one or more iliac shoulder regions, each of which diverges from the corresponding iliac neck region, wherein the endograft comprises:

an expanded configuration and a compressed configuration;

a modular device having a first modular component comprising a distal bulbous region and one or more additional modular components each comprising a proximal bulbous region, wherein, in the expanded configuration, the endograft further comprises;

a first endograft neck with a diameter approximately equal to the renal neck region width with the distal bulbous portion having at least a shoulder portion adapted to match the diverging width of the renal shoulder region, the distal bulbous portion having a length characterized by a diverging and converging diameter greater than the first endograft neck diameter along the bulbous portion length, the endograft having a diameter profile in the converging diameter part of the distal bulbous portion length that does not conform to the body lumen diameter profile; and an additional endograft neck with a diameter approximately equal to the iliac neck region width with the proximal bulbous portion having at least a shoulder portion adapted to match the diverging width of the iliac shoulder region, the proximal bulbous portion having a length characterized by a diverging and converging diameter greater than the additional endograft neck diameter along the bulbous portion length, the endograft having a diameter profile in the converging diameter part of the proximal bulbous portion length that does not conform to the body lumen diameter profile; and the endograft further comprises a plurality of affixation members suitable for affixing to the lumen wall, the affixation members being disposed along an axial region of the endograft including at least the first and additional endograft necks and the shoulder portion of the distal bulbous portion and the shoulder portion of the proximal bulbous portion;

wherein in the compressed configuration, the endograft is suitable for introduction into the body lumen to a deployment location;

wherein deployment of the first modular component of the endograft at a deployment location causes the shoulder portion of the distal bulbous portion to be aligned with the renal shoulder region and one or more of the affixation members in the first endograft neck to be affixed to the renal neck region and one or more of the affixation members in the distal bulbous portion to be affixed to at least a portion of the renal shoulder region; and wherein deployment of the one or more additional modular components of the endograft at a deployment location causes the shoulder portion of each proximal bulbous portion to be aligned with a corresponding iliac shoulder region and one or more of the affixation members in each additional endograft neck to be affixed to the corresponding iliac neck region and one or more of the affixation members in each proximal bulbous portion to be affixed to at least a portion of the corresponding iliac shoulder region, each of the one or more additional modular components mating with the first modular component such that a distal end of each additional modular component connects to a proximal end of the first modular component.
41. The use of claim 40, wherein the one or more additional modular components are adapted to reverse-deploying.
CA2526848A 2003-02-26 2004-02-09 Endoluminal device having enhanced affixation characteristics Expired - Fee Related CA2526848C (en)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US10/374,854 2003-02-26
US10/374,854 US7025779B2 (en) 2003-02-26 2003-02-26 Endoluminal device having enhanced affixation characteristics
PCT/US2004/003812 WO2004075791A1 (en) 2003-02-26 2004-02-09 Endoluminal device having enhanced affixation characteristics

Publications (2)

Publication Number Publication Date
CA2526848A1 CA2526848A1 (en) 2004-09-10
CA2526848C true CA2526848C (en) 2012-03-20

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CA2526848A1 (en) 2004-09-10
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EP1599152A1 (en) 2005-11-30
US7025779B2 (en) 2006-04-11
US20040167605A1 (en) 2004-08-26
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JP4825665B2 (en) 2011-11-30
US8663316B2 (en) 2014-03-04

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