CA2538172A1 - Apparatus and method for dispensing foam - Google Patents

Apparatus and method for dispensing foam Download PDF

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Publication number
CA2538172A1
CA2538172A1 CA002538172A CA2538172A CA2538172A1 CA 2538172 A1 CA2538172 A1 CA 2538172A1 CA 002538172 A CA002538172 A CA 002538172A CA 2538172 A CA2538172 A CA 2538172A CA 2538172 A1 CA2538172 A1 CA 2538172A1
Authority
CA
Canada
Prior art keywords
foam
outlet
waste
dispensing
syringe
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Granted
Application number
CA002538172A
Other languages
French (fr)
Other versions
CA2538172C (en
Inventor
Anthony David Harman
David Dakin Iorwerth Wright
Jan Willem Marinus Mijers
Stuart Brian William Kay
Christopher John Hurlstone
Julian Richard Dixon
Andrew Gordon Pocock
Brendan Hogan
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
BTG International Ltd
Original Assignee
Individual
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Individual filed Critical Individual
Publication of CA2538172A1 publication Critical patent/CA2538172A1/en
Application granted granted Critical
Publication of CA2538172C publication Critical patent/CA2538172C/en
Active legal-status Critical Current
Anticipated expiration legal-status Critical

Links

Classifications

    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B65—CONVEYING; PACKING; STORING; HANDLING THIN OR FILAMENTARY MATERIAL
    • B65D—CONTAINERS FOR STORAGE OR TRANSPORT OF ARTICLES OR MATERIALS, e.g. BAGS, BARRELS, BOTTLES, BOXES, CANS, CARTONS, CRATES, DRUMS, JARS, TANKS, HOPPERS, FORWARDING CONTAINERS; ACCESSORIES, CLOSURES, OR FITTINGS THEREFOR; PACKAGING ELEMENTS; PACKAGES
    • B65D83/00—Containers or packages with special means for dispensing contents
    • B65D83/14—Containers or packages with special means for dispensing contents for delivery of liquid or semi-liquid contents by internal gaseous pressure, i.e. aerosol containers comprising propellant for a product delivered by a propellant
    • B65D83/16—Containers or packages with special means for dispensing contents for delivery of liquid or semi-liquid contents by internal gaseous pressure, i.e. aerosol containers comprising propellant for a product delivered by a propellant characterised by the actuating means
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B65—CONVEYING; PACKING; STORING; HANDLING THIN OR FILAMENTARY MATERIAL
    • B65D—CONTAINERS FOR STORAGE OR TRANSPORT OF ARTICLES OR MATERIALS, e.g. BAGS, BARRELS, BOTTLES, BOXES, CANS, CARTONS, CRATES, DRUMS, JARS, TANKS, HOPPERS, FORWARDING CONTAINERS; ACCESSORIES, CLOSURES, OR FITTINGS THEREFOR; PACKAGING ELEMENTS; PACKAGES
    • B65D83/00—Containers or packages with special means for dispensing contents
    • B65D83/14—Containers or packages with special means for dispensing contents for delivery of liquid or semi-liquid contents by internal gaseous pressure, i.e. aerosol containers comprising propellant for a product delivered by a propellant
    • B65D83/16—Containers or packages with special means for dispensing contents for delivery of liquid or semi-liquid contents by internal gaseous pressure, i.e. aerosol containers comprising propellant for a product delivered by a propellant characterised by the actuating means
    • B65D83/20—Containers or packages with special means for dispensing contents for delivery of liquid or semi-liquid contents by internal gaseous pressure, i.e. aerosol containers comprising propellant for a product delivered by a propellant characterised by the actuating means operated by manual action, e.g. button-type actuator or actuator caps
    • B65D83/205—Actuator caps, or peripheral actuator skirts, attachable to the aerosol container
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/10—Dispersions; Emulsions
    • A61K9/12—Aerosols; Foams
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B65—CONVEYING; PACKING; STORING; HANDLING THIN OR FILAMENTARY MATERIAL
    • B65B—MACHINES, APPARATUS OR DEVICES FOR, OR METHODS OF, PACKAGING ARTICLES OR MATERIALS; UNPACKING
    • B65B3/00—Packaging plastic material, semiliquids, liquids or mixed solids and liquids, in individual containers or receptacles, e.g. bags, sacks, boxes, cartons, cans, or jars
    • B65B3/22—Defoaming liquids in connection with filling
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B65—CONVEYING; PACKING; STORING; HANDLING THIN OR FILAMENTARY MATERIAL
    • B65D—CONTAINERS FOR STORAGE OR TRANSPORT OF ARTICLES OR MATERIALS, e.g. BAGS, BARRELS, BOTTLES, BOXES, CANS, CARTONS, CRATES, DRUMS, JARS, TANKS, HOPPERS, FORWARDING CONTAINERS; ACCESSORIES, CLOSURES, OR FITTINGS THEREFOR; PACKAGING ELEMENTS; PACKAGES
    • B65D83/00—Containers or packages with special means for dispensing contents
    • B65D83/14—Containers or packages with special means for dispensing contents for delivery of liquid or semi-liquid contents by internal gaseous pressure, i.e. aerosol containers comprising propellant for a product delivered by a propellant
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B65—CONVEYING; PACKING; STORING; HANDLING THIN OR FILAMENTARY MATERIAL
    • B65D—CONTAINERS FOR STORAGE OR TRANSPORT OF ARTICLES OR MATERIALS, e.g. BAGS, BARRELS, BOTTLES, BOXES, CANS, CARTONS, CRATES, DRUMS, JARS, TANKS, HOPPERS, FORWARDING CONTAINERS; ACCESSORIES, CLOSURES, OR FITTINGS THEREFOR; PACKAGING ELEMENTS; PACKAGES
    • B65D83/00—Containers or packages with special means for dispensing contents
    • B65D83/14—Containers or packages with special means for dispensing contents for delivery of liquid or semi-liquid contents by internal gaseous pressure, i.e. aerosol containers comprising propellant for a product delivered by a propellant
    • B65D83/75—Aerosol containers not provided for in groups B65D83/16 - B65D83/74
    • B65D83/753—Aerosol containers not provided for in groups B65D83/16 - B65D83/74 characterised by details or accessories associated with outlets
    • B65D83/7532—Aerosol containers not provided for in groups B65D83/16 - B65D83/74 characterised by details or accessories associated with outlets comprising alternative flow directions or replaceable or interchangeable outlets
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B65—CONVEYING; PACKING; STORING; HANDLING THIN OR FILAMENTARY MATERIAL
    • B65D—CONTAINERS FOR STORAGE OR TRANSPORT OF ARTICLES OR MATERIALS, e.g. BAGS, BARRELS, BOTTLES, BOXES, CANS, CARTONS, CRATES, DRUMS, JARS, TANKS, HOPPERS, FORWARDING CONTAINERS; ACCESSORIES, CLOSURES, OR FITTINGS THEREFOR; PACKAGING ELEMENTS; PACKAGES
    • B65D83/00—Containers or packages with special means for dispensing contents
    • B65D83/14—Containers or packages with special means for dispensing contents for delivery of liquid or semi-liquid contents by internal gaseous pressure, i.e. aerosol containers comprising propellant for a product delivered by a propellant
    • B65D83/75—Aerosol containers not provided for in groups B65D83/16 - B65D83/74
    • B65D83/756—Aerosol containers not provided for in groups B65D83/16 - B65D83/74 comprising connectors, e.g. for tyre valves, or actuators connected to the aerosol container by a flexible tube

Abstract

A foam transfer device (600) is described, for use with aerosol canister apparatus for producing a sclerosant foam for the treatment of, inter alia, varicose veins. The device enables diversion of an initial quantity of below - specification foam from the canister to waste, e.g. to an integral waste chamber, before dispensing a further quantity of foam for use in treatment. The switching of the flow from the waste chamber to a different outlet (618) for use is accomplished without interrupting the flow from the aerosol canister since this would cause the foam to drop below specification again. The waste chamber may be transparent so that the foam entering it can be observed and a decision made by a user when to stop diverting foam to waste. Alternatively, the foam may be diverted automatically e.g. when a set time h as elapsed or a set volume of foam dispensed. The foam for use is normally dispensed into a syringe for subsequent injection into a varicose vein of a patient.

Claims (28)

1. Apparatus for dispensing foam comprising a source of foam and a dispensing device, the dispensing device comprising:
(a) an inlet in communication with the source of foam;
(b) a usable foam outlet;
(c) a waste bleed outlet communicating with the inlet, the bleed outlet having a higher resistance to flow of foam than that of the usable foam outlet.
2. Apparatus as claimed in claim 1 wherein the waste bleed outlet is located adjacent the usable foam outlet.
3. Apparatus as claimed in claim 1 or claim 2 further comprising a second waste outlet communicating with the usable foam outlet.
4. Apparatus as claimed in claim 3 wherein the second waste outlet has a lower resistance to flow of foam than that of the waste bleed outlet.
5. Apparatus as claimed in claim 3 or claim 4 wherein the communication between the second waste outlet and the usable foam outlet is via a valve arrangement
6. Apparatus as claimed in claim 5 wherein the valve arrangement comprises a diaphragm member.
7. Apparatus as claimed in any preceding claim comprising a substantially enclosed waste chamber with which the waste bleed outlet communicates.
8. Apparatus as claimed in claim 7 wherein at least a portion of a wall of the waste chamber is transparent to allow inspection of foam in the chamber.
9. Apparatus as claimed in claim 7 or claim 8 wherein the waste chamber forms an integral part of the dispensing device.
10. A device for dispensing foam comprising:
(a) an inlet for communication with a source of foam;
(b) a usable foam outlet;
a waste bleed outlet communicating with the inlet, the bleed outlet having a higher resistance to flow of foam than that of the usable foam outlet; and (c) a connector for mechanically securing the device to a source of foam.
11. A device as claimed in claim 10 wherein the waste bleed outlet is located adjacent the usable foam outlet.
12. A device as claimed in claim 10 or claim 11 further comprising a second waste outlet communicating with the usable foam outlet.
13. A device as claimed in claim 12 wherein the second waste outlet has a lower resistance to flow of foam than that of the waste bleed outlet.
14. A device as claimed in claim 12 or claim 13 wherein the communication between the second waste outlet and the usable foam outlet is via a one way valve arrangement
15. A device as claimed in claim 14 wherein the one way valve arrangement comprises a diaphragm member.
16. A device as claimed in any of claims 10 to 15 comprising a substantially enclosed waste chamber with which the waste bleed outlet communicates.
17. A device as claimed in claim 16 wherein at least a portion of a wall of the waste chamber is transparent to allow inspection of foam in the chamber.
18. A device as claimed in claim 16 or claim 17 wherein the waste chamber forms an integral part of the device.
19. A kit comprising a device as claimed in any of claims 10 to 18 in combination with a foam source, the said source being provided with a connector complementary to that of the dispensing device and with a foam outlet complementary to the foam inlet of the dispensing device.
20. A kit as claimed in claim 19 further comprising a syringe.
21. A kit as claimed in claim 19 or claim 20 wherein the foam source comprises a first canister containing liquid to be foamed and a second canister containing pressurized gas for charging the said first canister prior to generation of foam.
22. An assembly comprising a device as claimed in any of claims 10 to 18 in combination with a syringe, wherein the nozzle of the syringe is fitted into the usable foam outlet, and wherein the usable foam outlet with the syringe nozzle fitted therein has a lower resistance to flow of foam than that of the waste bleed outlet.
23. An assembly as claimed in claim 22 wherein the syringe nozzle is a standard luer nozzle and the usable foam outlet of the dispensing device is configured as a female luer connector.
24. An assembly as claimed in claim 22 wherein the syringe comprises a plunger having a projection extending into a nozzle of the syringe, whereby dead space in the syringe is minimised.
25. Apparatus as claimed in any of claims 1 to 9 wherein the source of foam comprises a canister charged with liquid and gas under pressure.
26. A method of dispensing foam comprising the steps of:
(a) dispensing foam to waste;
(b) observing the said foam being dispensed to waste and making a determination as to when the foam is of a predetermined quality;
(c) once the foam is of the said predetermined quality, dispensing foam to a separate location for subsequent use, whilst continuing to dispense foam to waste;
(d) wherein the rate at which foam is dispensed to waste is lower than the rate at which foam is dispensed to the said separate location for subsequent use.
27. A method of dispensing foam using the apparatus claimed in any of claims 1 to 9 comprising the steps of:
(a) providing a syringe fitted to the usable foam outlet of the dispensing device;
(b) whilst holding a plunger of the syringe in a fully depressed position, causing foam from the source to flow into the foam inlet of the dispensing device and thence out of the waste bleed outlet;
(c) observing the said foam exiting the waste bleed outlet;
(d) when the said foam exiting the bleed outlet is observed to have a predetermined quality, releasing the plunger of the syringe, whereby the syringe fills with foam.
28. A method of dispensing foam from a pressurized container comprising the steps of:-(a) initially dispensing a continuous flow of foam to waste; and then (b) subsequently diverting at least a proportion of the said flow of foam to a vessel for further use, without substantial interruption of the flow of foam from the canister.
CA2538172A 2003-09-10 2004-09-09 Apparatus and method for dispensing foam Active CA2538172C (en)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
GB0321210.7 2003-09-10
GBGB0321210.7A GB0321210D0 (en) 2003-09-10 2003-09-10 Apparatus and method for dispensing foam
PCT/GB2004/003864 WO2005023678A1 (en) 2003-09-10 2004-09-09 Apparatus and method for dispensing foam

Publications (2)

Publication Number Publication Date
CA2538172A1 true CA2538172A1 (en) 2005-03-17
CA2538172C CA2538172C (en) 2011-12-06

Family

ID=29226843

Family Applications (1)

Application Number Title Priority Date Filing Date
CA2538172A Active CA2538172C (en) 2003-09-10 2004-09-09 Apparatus and method for dispensing foam

Country Status (19)

Country Link
US (2) US7814943B2 (en)
EP (1) EP1673293B1 (en)
JP (2) JP4731483B2 (en)
KR (1) KR101274639B1 (en)
CN (1) CN1878706B (en)
AT (1) ATE486023T1 (en)
AU (1) AU2004270475B8 (en)
BR (1) BRPI0414281B1 (en)
CA (1) CA2538172C (en)
CY (1) CY1111096T1 (en)
DE (1) DE602004029802D1 (en)
DK (1) DK1673293T3 (en)
ES (1) ES2354695T3 (en)
GB (1) GB0321210D0 (en)
PL (1) PL1673293T3 (en)
PT (1) PT1673293E (en)
RU (1) RU2344060C2 (en)
SI (1) SI1673293T1 (en)
WO (1) WO2005023678A1 (en)

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US8651305B1 (en) 2009-09-30 2014-02-18 Simplified Dosing Incorporated Reclosable container closure
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EP2755770A1 (en) 2011-09-13 2014-07-23 Caporal Piotrovski, Murillo Rechargeable and resterilizable mixing device with physiological gas and solution to create foam with microbubbles, used in endovascular treatments
GB2510400A (en) * 2013-02-01 2014-08-06 Cambridge Consultants Foam Dispenser
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US9687455B2 (en) 2014-08-14 2017-06-27 John Daniel Dobak Sodium tetradecyl sulfate formulations for treatment of adipose tissue
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Also Published As

Publication number Publication date
GB0321210D0 (en) 2003-10-08
BRPI0414281A (en) 2006-11-21
ATE486023T1 (en) 2010-11-15
AU2004270475A1 (en) 2005-03-17
SI1673293T1 (en) 2011-02-28
KR20060121915A (en) 2006-11-29
ES2354695T3 (en) 2011-03-17
WO2005023678A1 (en) 2005-03-17
PT1673293E (en) 2011-01-05
BRPI0414281B1 (en) 2018-05-02
CN1878706A (en) 2006-12-13
JP4731483B2 (en) 2011-07-27
KR101274639B1 (en) 2013-06-13
PL1673293T3 (en) 2011-05-31
RU2006111474A (en) 2007-10-20
US7814943B2 (en) 2010-10-19
EP1673293B1 (en) 2010-10-27
CN1878706B (en) 2011-03-09
CA2538172C (en) 2011-12-06
AU2004270475B2 (en) 2011-06-30
DE602004029802D1 (en) 2010-12-09
DK1673293T3 (en) 2011-01-31
JP5107445B2 (en) 2012-12-26
CY1111096T1 (en) 2015-06-11
WO2005023678A8 (en) 2006-01-19
RU2344060C2 (en) 2009-01-20
US20070051426A1 (en) 2007-03-08
JP2007504872A (en) 2007-03-08
JP2011136192A (en) 2011-07-14
AU2004270475B8 (en) 2011-11-10
US20110024448A1 (en) 2011-02-03
EP1673293A1 (en) 2006-06-28
US8122917B2 (en) 2012-02-28

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