CA2538677A1 - Analytical aid - Google Patents

Analytical aid Download PDF

Info

Publication number
CA2538677A1
CA2538677A1 CA002538677A CA2538677A CA2538677A1 CA 2538677 A1 CA2538677 A1 CA 2538677A1 CA 002538677 A CA002538677 A CA 002538677A CA 2538677 A CA2538677 A CA 2538677A CA 2538677 A1 CA2538677 A1 CA 2538677A1
Authority
CA
Canada
Prior art keywords
analytical aid
subsidiary
lancet
sample
seal
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Granted
Application number
CA002538677A
Other languages
French (fr)
Other versions
CA2538677C (en
Inventor
Herbert Harttig
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
F Hoffmann La Roche AG
Original Assignee
F Hoffmann La Roche AG
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by F Hoffmann La Roche AG filed Critical F Hoffmann La Roche AG
Publication of CA2538677A1 publication Critical patent/CA2538677A1/en
Application granted granted Critical
Publication of CA2538677C publication Critical patent/CA2538677C/en
Expired - Fee Related legal-status Critical Current
Anticipated expiration legal-status Critical

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B5/00—Measuring for diagnostic purposes; Identification of persons
    • A61B5/15—Devices for taking samples of blood
    • A61B5/150007—Details
    • A61B5/150374—Details of piercing elements or protective means for preventing accidental injuries by such piercing elements
    • A61B5/150534—Design of protective means for piercing elements for preventing accidental needle sticks, e.g. shields, caps, protectors, axially extensible sleeves, pivotable protective sleeves
    • A61B5/150541—Breakable protectors, e.g. caps, shields or sleeves, i.e. protectors separated destructively, e.g. by breaking a connecting area
    • A61B5/150557—Protectors removed by bending
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B5/00—Measuring for diagnostic purposes; Identification of persons
    • A61B5/15—Devices for taking samples of blood
    • A61B5/150007—Details
    • A61B5/150015—Source of blood
    • A61B5/150022—Source of blood for capillary blood or interstitial fluid
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B5/00—Measuring for diagnostic purposes; Identification of persons
    • A61B5/15—Devices for taking samples of blood
    • A61B5/150007—Details
    • A61B5/150358—Strips for collecting blood, e.g. absorbent
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B5/00—Measuring for diagnostic purposes; Identification of persons
    • A61B5/15—Devices for taking samples of blood
    • A61B5/150007—Details
    • A61B5/150374—Details of piercing elements or protective means for preventing accidental injuries by such piercing elements
    • A61B5/150381—Design of piercing elements
    • A61B5/150412—Pointed piercing elements, e.g. needles, lancets for piercing the skin
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B5/00—Measuring for diagnostic purposes; Identification of persons
    • A61B5/15—Devices for taking samples of blood
    • A61B5/150007—Details
    • A61B5/150374—Details of piercing elements or protective means for preventing accidental injuries by such piercing elements
    • A61B5/150381—Design of piercing elements
    • A61B5/150503—Single-ended needles
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B5/00—Measuring for diagnostic purposes; Identification of persons
    • A61B5/15—Devices for taking samples of blood
    • A61B5/150007—Details
    • A61B5/150374—Details of piercing elements or protective means for preventing accidental injuries by such piercing elements
    • A61B5/150534—Design of protective means for piercing elements for preventing accidental needle sticks, e.g. shields, caps, protectors, axially extensible sleeves, pivotable protective sleeves
    • A61B5/15058—Joining techniques used for protective means
    • A61B5/150618—Integrally moulded protectors, e.g. protectors simultaneously moulded together with a further component, e.g. a hub, of the piercing element
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B5/00—Measuring for diagnostic purposes; Identification of persons
    • A61B5/15—Devices for taking samples of blood
    • A61B5/150007—Details
    • A61B5/150374—Details of piercing elements or protective means for preventing accidental injuries by such piercing elements
    • A61B5/150534—Design of protective means for piercing elements for preventing accidental needle sticks, e.g. shields, caps, protectors, axially extensible sleeves, pivotable protective sleeves
    • A61B5/150664—Pivotable protective sleeves, i.e. sleeves connected to, or integrated in, the piercing or driving device, and which are pivoted for covering or uncovering the piercing element
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B5/00—Measuring for diagnostic purposes; Identification of persons
    • A61B5/15—Devices for taking samples of blood
    • A61B5/150007—Details
    • A61B5/150374—Details of piercing elements or protective means for preventing accidental injuries by such piercing elements
    • A61B5/150534—Design of protective means for piercing elements for preventing accidental needle sticks, e.g. shields, caps, protectors, axially extensible sleeves, pivotable protective sleeves
    • A61B5/150694—Procedure for removing protection means at the time of piercing
    • A61B5/150702—Procedure for removing protection means at the time of piercing fully automatically removed, i.e. the removing does not require any action by the user
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B5/00—Measuring for diagnostic purposes; Identification of persons
    • A61B5/15—Devices for taking samples of blood
    • A61B5/150007—Details
    • A61B5/150801—Means for facilitating use, e.g. by people with impaired vision; means for indicating when used correctly or incorrectly; means for alarming
    • A61B5/150809—Means for facilitating use, e.g. by people with impaired vision; means for indicating when used correctly or incorrectly; means for alarming by audible feedback
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B5/00—Measuring for diagnostic purposes; Identification of persons
    • A61B5/15—Devices for taking samples of blood
    • A61B5/151—Devices specially adapted for taking samples of capillary blood, e.g. by lancets, needles or blades
    • A61B5/15101—Details
    • A61B5/15126—Means for controlling the lancing movement, e.g. 2D- or 3D-shaped elements, tooth-shaped elements or sliding guides
    • A61B5/1513—Means for controlling the lancing movement, e.g. 2D- or 3D-shaped elements, tooth-shaped elements or sliding guides comprising linear sliding guides
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B5/00—Measuring for diagnostic purposes; Identification of persons
    • A61B5/15—Devices for taking samples of blood
    • A61B5/151—Devices specially adapted for taking samples of capillary blood, e.g. by lancets, needles or blades
    • A61B5/15146—Devices loaded with multiple lancets simultaneously, e.g. for serial firing without reloading, for example by use of stocking means.
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B5/00—Measuring for diagnostic purposes; Identification of persons
    • A61B5/15—Devices for taking samples of blood
    • A61B5/151—Devices specially adapted for taking samples of capillary blood, e.g. by lancets, needles or blades
    • A61B5/15186—Devices loaded with a single lancet, i.e. a single lancet with or without a casing is loaded into a reusable drive device and then discarded after use; drive devices reloadable for multiple use
    • A61B5/15188—Constructional features of reusable driving devices
    • A61B5/1519—Constructional features of reusable driving devices comprising driving means, e.g. a spring, for propelling the piercing unit
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B5/00—Measuring for diagnostic purposes; Identification of persons
    • A61B5/15—Devices for taking samples of blood
    • A61B5/151—Devices specially adapted for taking samples of capillary blood, e.g. by lancets, needles or blades
    • A61B5/15186—Devices loaded with a single lancet, i.e. a single lancet with or without a casing is loaded into a reusable drive device and then discarded after use; drive devices reloadable for multiple use
    • A61B5/15188—Constructional features of reusable driving devices
    • A61B5/15192—Constructional features of reusable driving devices comprising driving means, e.g. a spring, for retracting the lancet unit into the driving device housing
    • A61B5/15194—Constructional features of reusable driving devices comprising driving means, e.g. a spring, for retracting the lancet unit into the driving device housing fully automatically retracted, i.e. the retraction does not require a deliberate action by the user, e.g. by terminating the contact with the patient's skin
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B5/00—Measuring for diagnostic purposes; Identification of persons
    • A61B5/145—Measuring characteristics of blood in vivo, e.g. gas concentration, pH value; Measuring characteristics of body fluids or tissues, e.g. interstitial fluid, cerebral tissue
    • A61B5/14532—Measuring characteristics of blood in vivo, e.g. gas concentration, pH value; Measuring characteristics of body fluids or tissues, e.g. interstitial fluid, cerebral tissue for measuring glucose, e.g. by tissue impedance measurement
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B5/00—Measuring for diagnostic purposes; Identification of persons
    • A61B5/15—Devices for taking samples of blood
    • A61B5/151—Devices specially adapted for taking samples of capillary blood, e.g. by lancets, needles or blades
    • A61B5/15101—Details
    • A61B5/15103—Piercing procedure
    • A61B5/15107—Piercing being assisted by a triggering mechanism
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B5/00—Measuring for diagnostic purposes; Identification of persons
    • A61B5/15—Devices for taking samples of blood
    • A61B5/151—Devices specially adapted for taking samples of capillary blood, e.g. by lancets, needles or blades
    • A61B5/15101—Details
    • A61B5/15115—Driving means for propelling the piercing element to pierce the skin, e.g. comprising mechanisms based on shape memory alloys, magnetism, solenoids, piezoelectric effect, biased elements, resilient elements, vacuum or compressed fluids
    • A61B5/15117—Driving means for propelling the piercing element to pierce the skin, e.g. comprising mechanisms based on shape memory alloys, magnetism, solenoids, piezoelectric effect, biased elements, resilient elements, vacuum or compressed fluids comprising biased elements, resilient elements or a spring, e.g. a helical spring, leaf spring, or elastic strap
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B5/00—Measuring for diagnostic purposes; Identification of persons
    • A61B5/15—Devices for taking samples of blood
    • A61B5/151—Devices specially adapted for taking samples of capillary blood, e.g. by lancets, needles or blades
    • A61B5/15101—Details
    • A61B5/15115—Driving means for propelling the piercing element to pierce the skin, e.g. comprising mechanisms based on shape memory alloys, magnetism, solenoids, piezoelectric effect, biased elements, resilient elements, vacuum or compressed fluids
    • A61B5/15123—Driving means for propelling the piercing element to pierce the skin, e.g. comprising mechanisms based on shape memory alloys, magnetism, solenoids, piezoelectric effect, biased elements, resilient elements, vacuum or compressed fluids comprising magnets or solenoids
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B5/00—Measuring for diagnostic purposes; Identification of persons
    • A61B5/72—Signal processing specially adapted for physiological signals or for diagnostic purposes
    • A61B5/7203—Signal processing specially adapted for physiological signals or for diagnostic purposes for noise prevention, reduction or removal
    • A61B5/7207—Signal processing specially adapted for physiological signals or for diagnostic purposes for noise prevention, reduction or removal of noise induced by motion artifacts

Abstract

The invention relates to an analytical aid comprising a base body (2), a lancet (6) and a test element (8), where i) the base body (2) comprises two subsidiary bodies (4, 5) connected to one another via a hinge-like connection (3), a first subsidiary body (4) carrying the lancet (6) with lancet tip (7), and a second subsidiary body (5) carrying the test element (8), with test field (17), and a sample application site (9), and ii) the two subsidiary bodies (4, 5) are arranged substantially in a common plane, and the lancet (6) is protected by a seal (10) connected to the first subsidiary body (4) and is separated from the test field (17) of the test element (8) as long as the analytical aid (1) is in an unused state, the two subsidiary bodies (4, 5) being pivotable relative to one another out of the plane about the hinge-like connection (3), and the seal (10) being openable so that the lancet tip (7) is released for use.

Claims (21)

1. Analytical aid comprising a base body (2), a lancet (6) and a test element (8), characterized in that i) the base body (2) comprises two subsidiary bodies (4, 5) connected to one another via a hinge-like connection (3), a first subsidiary body (4) carrying the lancet (6) with lancet tip (7), and a second subsidiary body (5) carrying the test element (8), with test field (17), and a sample application site (9), and ii) the two subsidiary bodies (4, 5) are arranged substantially in a common plane, and the lancet (6) is protected by a seal (10) connected to the first subsidiary body (4) and is separated from the test field (17) of the test element (8) as long as the analytical aid (1) is in an unused state, the two subsidiary bodies (4, 5) being pivotable relative to one another out of the plane about the hinge-like connection (3), and the seal (10) being openable so that the lancet tip (7) is released for use.
2. Analytical aid according to Claim 1, characterized in that the seal (10) can be opened upon pivoting of the two subsidiary bodies (4, 5).
3. Analytical aid according to either of Claims 1 and 2, characterized in that the hinge-like connection (3) is a flexible strip that connects the two subsidiary bodies (4, 5) to one another.
4. Analytical aid according to one of Claims 1 to 3, characterized in that the sample application site (9) is arranged in the area of an end (11) of the second subsidiary body (5) remote from the hinge-like connection (3).
5. Analytical aid according to one of Claims 1 to 4, characterized in that the lancet tip (7) protrudes beyond the first subsidiary body (4) in the area of the hinge-like connection (3).
6. Analytical aid according to one of Claims 1 to 5, characterized in that the lancet tip (7) is oriented substantially parallel to the second subsidiary body (5) in the unused state of the analytical aid (1).
7. Analytical aid according to one of Claims 1 to 6, characterized in that the seal (10) is a pocket-like guard which partially or completely encloses the lancet (6) in the unused state of the analytical aid (1).
8. Analytical aid according to one of Claims 1 to 7, characterized in that the seal (10) at the lancet tip (7) is connected fixedly to the second subsidiary body (5).
9. Analytical aid according to one of Claims 1 to 8, characterized in that the hinge-like connection (3) is formed by the seal (10).
10. Analytical aid according to one of Claims 1 to 9, characterized in that the test element (8) comprises means for electrochemical or optical analysis of a sample present on the test field (17).
11. Analytical aid according to one of Claims 1 to 10, characterized in that the first subsidiary body (4) has a recess (15) for engagement of a guide element (26) belonging to an analysis device via which the analytical aid (1) is guided to a sample collection location (27) for puncturing with the lancet (6) and for application of the sample.
12. Analytical aid according to one of Claims 1 to 11, characterized by a cover (30) which is arranged on the analytical aid (1) and which is connected fixedly to the first subsidiary body (4) and is connected releasably and reconnectably to the second subsidiary body (5) via an adhesion zone (32).
13. Analytical aid according to one of Claims 1 to 12, characterized in that the second subsidiary body (5) carries a means for sample transport (18) from the sample application site (9) to the test field (17), which is a capillary.
14. Magazine, containing at least one analytical aid according to one of Claims 1 to 13 that is stored in a magazine.
15. Method for producing analytical aids according to one of Claims 1 to 13, characterized in that the first subsidiary bodies (4) are produced from sections of a first band and the second subsidiary bodies (5) are produced from sections of a second band, the two bands being oriented relative to one another, with the aid of pilot holes, before they are connected to one another into base bodies (2) and the sections are separated.
16. Method according to Claim 15, characterized in that a lancet (6) is in each case secured on one section of the first band and is provided with a seal (10), and the lancets (6) are sterilized before the two bands are connected to one another.
17. Method according to Claim 16, characterized in that the seal (10) is controlled in a vacuum.
18. Method for analysis of a sample using an analytical aid according to one of Claims 1 to 13, comprising the following steps:
A) inserting an analytical aid (1) into an analysis device, B) pivoting the two subsidiary bodies (4, 5) relative to one another from a starting position through an angle .alpha., whereupon the seal (10) is opened and the lancet tip (7), protruding beyond the first subsidiary body (4), is released for use, C) inserting the lancet tip (7) into a sample collection location (27), D) pivoting the two subsidiary bodies (4, 5) into the starting position or into another sample application position, E) applying the sample from the sample collection location (27) onto the sample application site (9) of the analytical aid (1) so that the sample reaches the test field (17), and F) analysing the sample on the test field (17).
19. Method according to Claim 18, characterized in that the lancet tip (7) in step C) emerges from an opening (39) of the analysis device, and the sample application site (9) in step E) emerges from the opening (39).
20. Method according to either of Claims 18 and 19, characterized in that the analytical aid is made ready from a magazine in an analysis device.
21. Method according to Claim 20, characterized in that the analytical aid is received in a magazine after use.
CA2538677A 2005-04-22 2006-03-07 Analytical aid Expired - Fee Related CA2538677C (en)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
EPEP05008.933.3 2005-04-22
EP05008933A EP1714613A1 (en) 2005-04-22 2005-04-22 Analyzing means

Publications (2)

Publication Number Publication Date
CA2538677A1 true CA2538677A1 (en) 2006-10-22
CA2538677C CA2538677C (en) 2011-02-15

Family

ID=34935636

Family Applications (1)

Application Number Title Priority Date Filing Date
CA2538677A Expired - Fee Related CA2538677C (en) 2005-04-22 2006-03-07 Analytical aid

Country Status (6)

Country Link
US (1) US8007445B2 (en)
EP (2) EP1714613A1 (en)
JP (1) JP4468324B2 (en)
AT (1) ATE493932T1 (en)
CA (1) CA2538677C (en)
DE (1) DE502006008637D1 (en)

Families Citing this family (79)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US6036924A (en) 1997-12-04 2000-03-14 Hewlett-Packard Company Cassette of lancet cartridges for sampling blood
US6391005B1 (en) 1998-03-30 2002-05-21 Agilent Technologies, Inc. Apparatus and method for penetration with shaft having a sensor for sensing penetration depth
US8641644B2 (en) 2000-11-21 2014-02-04 Sanofi-Aventis Deutschland Gmbh Blood testing apparatus having a rotatable cartridge with multiple lancing elements and testing means
US7041068B2 (en) 2001-06-12 2006-05-09 Pelikan Technologies, Inc. Sampling module device and method
ES2357887T3 (en) 2001-06-12 2011-05-03 Pelikan Technologies Inc. APPARATUS FOR IMPROVING THE BLOOD OBTAINING SUCCESS RATE FROM A CAPILLARY PUNCTURE.
AU2002348683A1 (en) 2001-06-12 2002-12-23 Pelikan Technologies, Inc. Method and apparatus for lancet launching device integrated onto a blood-sampling cartridge
US9427532B2 (en) 2001-06-12 2016-08-30 Sanofi-Aventis Deutschland Gmbh Tissue penetration device
WO2002100460A2 (en) 2001-06-12 2002-12-19 Pelikan Technologies, Inc. Electric lancet actuator
EP1404232B1 (en) 2001-06-12 2009-12-02 Pelikan Technologies Inc. Blood sampling apparatus and method
US7316700B2 (en) 2001-06-12 2008-01-08 Pelikan Technologies, Inc. Self optimizing lancing device with adaptation means to temporal variations in cutaneous properties
US7981056B2 (en) 2002-04-19 2011-07-19 Pelikan Technologies, Inc. Methods and apparatus for lancet actuation
US9795747B2 (en) 2010-06-02 2017-10-24 Sanofi-Aventis Deutschland Gmbh Methods and apparatus for lancet actuation
US9226699B2 (en) 2002-04-19 2016-01-05 Sanofi-Aventis Deutschland Gmbh Body fluid sampling module with a continuous compression tissue interface surface
US8337419B2 (en) 2002-04-19 2012-12-25 Sanofi-Aventis Deutschland Gmbh Tissue penetration device
US7901362B2 (en) 2002-04-19 2011-03-08 Pelikan Technologies, Inc. Method and apparatus for penetrating tissue
US7674232B2 (en) 2002-04-19 2010-03-09 Pelikan Technologies, Inc. Method and apparatus for penetrating tissue
US7909778B2 (en) 2002-04-19 2011-03-22 Pelikan Technologies, Inc. Method and apparatus for penetrating tissue
US9248267B2 (en) 2002-04-19 2016-02-02 Sanofi-Aventis Deustchland Gmbh Tissue penetration device
US7371247B2 (en) 2002-04-19 2008-05-13 Pelikan Technologies, Inc Method and apparatus for penetrating tissue
US7976476B2 (en) 2002-04-19 2011-07-12 Pelikan Technologies, Inc. Device and method for variable speed lancet
US7491178B2 (en) 2002-04-19 2009-02-17 Pelikan Technologies, Inc. Method and apparatus for penetrating tissue
US8221334B2 (en) 2002-04-19 2012-07-17 Sanofi-Aventis Deutschland Gmbh Method and apparatus for penetrating tissue
US8702624B2 (en) 2006-09-29 2014-04-22 Sanofi-Aventis Deutschland Gmbh Analyte measurement device with a single shot actuator
US7291117B2 (en) 2002-04-19 2007-11-06 Pelikan Technologies, Inc. Method and apparatus for penetrating tissue
US7892183B2 (en) 2002-04-19 2011-02-22 Pelikan Technologies, Inc. Method and apparatus for body fluid sampling and analyte sensing
US7229458B2 (en) 2002-04-19 2007-06-12 Pelikan Technologies, Inc. Method and apparatus for penetrating tissue
US7175642B2 (en) 2002-04-19 2007-02-13 Pelikan Technologies, Inc. Methods and apparatus for lancet actuation
US9795334B2 (en) 2002-04-19 2017-10-24 Sanofi-Aventis Deutschland Gmbh Method and apparatus for penetrating tissue
US7708701B2 (en) 2002-04-19 2010-05-04 Pelikan Technologies, Inc. Method and apparatus for a multi-use body fluid sampling device
US7547287B2 (en) 2002-04-19 2009-06-16 Pelikan Technologies, Inc. Method and apparatus for penetrating tissue
US7648468B2 (en) 2002-04-19 2010-01-19 Pelikon Technologies, Inc. Method and apparatus for penetrating tissue
US8784335B2 (en) 2002-04-19 2014-07-22 Sanofi-Aventis Deutschland Gmbh Body fluid sampling device with a capacitive sensor
US7331931B2 (en) 2002-04-19 2008-02-19 Pelikan Technologies, Inc. Method and apparatus for penetrating tissue
US7232451B2 (en) 2002-04-19 2007-06-19 Pelikan Technologies, Inc. Method and apparatus for penetrating tissue
US7297122B2 (en) 2002-04-19 2007-11-20 Pelikan Technologies, Inc. Method and apparatus for penetrating tissue
US8267870B2 (en) 2002-04-19 2012-09-18 Sanofi-Aventis Deutschland Gmbh Method and apparatus for body fluid sampling with hybrid actuation
US7717863B2 (en) 2002-04-19 2010-05-18 Pelikan Technologies, Inc. Method and apparatus for penetrating tissue
US9314194B2 (en) 2002-04-19 2016-04-19 Sanofi-Aventis Deutschland Gmbh Tissue penetration device
US8579831B2 (en) 2002-04-19 2013-11-12 Sanofi-Aventis Deutschland Gmbh Method and apparatus for penetrating tissue
US8052926B2 (en) * 2002-12-27 2011-11-08 Roche Diagnostics Operations, Inc. Method for manufacturing a sterilized lancet integrated biosensor
US8574895B2 (en) 2002-12-30 2013-11-05 Sanofi-Aventis Deutschland Gmbh Method and apparatus using optical techniques to measure analyte levels
US7850621B2 (en) 2003-06-06 2010-12-14 Pelikan Technologies, Inc. Method and apparatus for body fluid sampling and analyte sensing
WO2006001797A1 (en) 2004-06-14 2006-01-05 Pelikan Technologies, Inc. Low pain penetrating
WO2005033659A2 (en) 2003-09-29 2005-04-14 Pelikan Technologies, Inc. Method and apparatus for an improved sample capture device
US9351680B2 (en) 2003-10-14 2016-05-31 Sanofi-Aventis Deutschland Gmbh Method and apparatus for a variable user interface
US8668656B2 (en) 2003-12-31 2014-03-11 Sanofi-Aventis Deutschland Gmbh Method and apparatus for improving fluidic flow and sample capture
US7822454B1 (en) 2005-01-03 2010-10-26 Pelikan Technologies, Inc. Fluid sampling device with improved analyte detecting member configuration
US8828203B2 (en) 2004-05-20 2014-09-09 Sanofi-Aventis Deutschland Gmbh Printable hydrogels for biosensors
EP1765194A4 (en) 2004-06-03 2010-09-29 Pelikan Technologies Inc Method and apparatus for a fluid sampling device
US8652831B2 (en) 2004-12-30 2014-02-18 Sanofi-Aventis Deutschland Gmbh Method and apparatus for analyte measurement test time
US9332938B2 (en) * 2005-03-02 2016-05-10 Roche Diabetes Care, Inc. Flat lancet immobilization
WO2006100265A1 (en) * 2005-03-24 2006-09-28 F. Hoffmann-La Roche Ag Analytical aid with a lancet and a testing element
EP1960772A1 (en) * 2005-11-21 2008-08-27 Inverness Medical Switzerland GmbH Test device
EP1878386A1 (en) * 2006-07-15 2008-01-16 Roche Diagnostics GmbH Process to produce lancet; lancet, lancet band and device for pricking the skin
EP1894526A1 (en) * 2006-09-04 2008-03-05 F. Hoffmann-la Roche AG Lancet
ATE547985T1 (en) * 2006-09-04 2012-03-15 Hoffmann La Roche PACKAGING FOR HYDROPHILE MEDICAL INSTRUMENTS
US8852124B2 (en) * 2006-10-13 2014-10-07 Roche Diagnostics Operations, Inc. Tape transport lance sampler
EP1943948A1 (en) * 2007-01-13 2008-07-16 Roche Diagnostics GmbH Puncture instrument
CA2674285C (en) * 2007-01-13 2017-10-24 F. Hoffmann-La Roche Ag Lancing device with bending mechanism
EP1990001A1 (en) 2007-05-10 2008-11-12 Roche Diagnostics GmbH Piercing system and fleam conveyor
EP1992284A1 (en) * 2007-05-15 2008-11-19 F.Hoffmann-La Roche Ag Method for storing piecing elements and belt magazine
ES2354912T3 (en) * 2007-05-16 2011-03-21 Roche Diagnostics Gmbh PUNCTURE SYSTEM
WO2009008193A1 (en) * 2007-07-11 2009-01-15 Nitto Denko Corporation Body fluid collecting circuit board
ATE492211T1 (en) * 2007-07-17 2011-01-15 Hoffmann La Roche DEVICE FOR EXTRACTING BODY FLUID
ATE488179T1 (en) * 2007-10-12 2010-12-15 Hoffmann La Roche TEST BAND DEVICE FOR EXAMINING BODY FLUID
US7766846B2 (en) 2008-01-28 2010-08-03 Roche Diagnostics Operations, Inc. Rapid blood expression and sampling
US20100292610A1 (en) * 2008-02-06 2010-11-18 Jun Ishii Circuit board for body fluid collection
KR20110004845A (en) * 2008-02-27 2011-01-14 엠오엔4디 엘티디 Device, system and method for modular analyte monitoring
JP2009225935A (en) * 2008-03-21 2009-10-08 Nitto Denko Corp Bodily fluid collecting circuit board and biosensor
US9386944B2 (en) 2008-04-11 2016-07-12 Sanofi-Aventis Deutschland Gmbh Method and apparatus for analyte detecting device
US9375169B2 (en) 2009-01-30 2016-06-28 Sanofi-Aventis Deutschland Gmbh Cam drive for managing disposable penetrating member actions with a single motor and motor and control system
ATE535189T1 (en) 2009-04-03 2011-12-15 Hoffmann La Roche DEVICE FOR COLLECTING AND ANALYZING A BLOOD SAMPLE
US8337423B2 (en) * 2009-07-14 2012-12-25 Becton, Dickinson And Company Blood glucose sensor
US8965476B2 (en) 2010-04-16 2015-02-24 Sanofi-Aventis Deutschland Gmbh Tissue penetration device
US20130281802A1 (en) * 2010-11-16 2013-10-24 Olympus Corporation Sensor system, and method of using sensor system
US10398361B2 (en) * 2012-01-10 2019-09-03 Becton, Dickinson And Company Low cost blood collection set using blister package
US10034645B1 (en) 2017-04-13 2018-07-31 The Board Of Trustees Of The Leland Stanford Junior University Systems and methods for detecting complex networks in MRI image data
US10856782B2 (en) * 2018-12-19 2020-12-08 Anand Kumar Chavakula Multi-use monitor
GB2622865A (en) * 2022-09-30 2024-04-03 Cambridge Entpr Ltd A housing for sample collection

Family Cites Families (19)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE8007991U1 (en) 1980-03-22 1981-04-09 Clinicon Mannheim GmbH, 6800 Mannheim Blood lancet device for drawing blood for diagnostic purposes
GB8417949D0 (en) * 1984-07-13 1984-08-15 Palmer G C Sampling fluid
NL8401536A (en) 1984-05-11 1985-12-02 Medscan B V I O BLOOD SAMPLING UNIT.
DE3515420A1 (en) * 1985-04-29 1986-10-30 Fischer, Artur, Dr.H.C., 7244 Waldachtal Blood glucose testing unit
DE4320463A1 (en) 1993-06-21 1994-12-22 Boehringer Mannheim Gmbh Blood lancet device for drawing blood for diagnostic purposes
GB9619462D0 (en) * 1996-09-18 1996-10-30 Owen Mumford Ltd Improvements relating to lancet devices
DE19718081A1 (en) 1997-04-29 1998-11-05 Boehringer Mannheim Gmbh Disposable blood lancet
DE19753847A1 (en) 1997-12-04 1999-06-10 Roche Diagnostics Gmbh Analytical test element with capillary channel
CZ296644B6 (en) 1998-04-24 2006-05-17 Roche Diagnostics Gmbh Storage container for use in compact measuring instrument to hold analytical devices
DE19840856B4 (en) * 1998-09-07 2008-04-10 Roche Diagnostics Gmbh System for obtaining a body fluid, lancet magazine, lancet, lancet set, lancing device and method for removing a lancet from a lancet magazine and use of the system
EP1139873B1 (en) * 1999-01-04 2008-09-17 Terumo Kabushiki Kaisha Body fluid collecting and detecting lancet assembly
EP1203563A3 (en) * 2000-10-31 2004-01-02 Boehringer Mannheim Gmbh Analyzing mean with integrated lancet
DE10142232B4 (en) 2001-08-29 2021-04-29 Roche Diabetes Care Gmbh Process for the production of an analytical aid with a lancet and test element
US20030211619A1 (en) 2002-05-09 2003-11-13 Lorin Olson Continuous strip of fluid sampling and testing devices and methods of making, packaging and using the same
US7343188B2 (en) * 2002-05-09 2008-03-11 Lifescan, Inc. Devices and methods for accessing and analyzing physiological fluid
US7192405B2 (en) 2002-09-30 2007-03-20 Becton, Dickinson And Company Integrated lancet and bodily fluid sensor
US7223248B2 (en) * 2003-08-13 2007-05-29 Lifescan, Inc. Packaged medical device with a deployable dermal tissue penetration member
US7909776B2 (en) * 2004-04-30 2011-03-22 Roche Diagnostics Operations, Inc. Lancets for bodily fluid sampling supplied on a tape
US7766845B2 (en) * 2004-06-21 2010-08-03 Roche Diagnostics Operations, Inc. Disposable lancet and lancing cap combination for increased hygiene

Also Published As

Publication number Publication date
US20060247555A1 (en) 2006-11-02
CA2538677C (en) 2011-02-15
US8007445B2 (en) 2011-08-30
JP2006297103A (en) 2006-11-02
EP1714614A3 (en) 2009-04-22
EP1714614A2 (en) 2006-10-25
EP1714613A1 (en) 2006-10-25
JP4468324B2 (en) 2010-05-26
ATE493932T1 (en) 2011-01-15
DE502006008637D1 (en) 2011-02-17
EP1714614B1 (en) 2011-01-05

Similar Documents

Publication Publication Date Title
CA2538677A1 (en) Analytical aid
WO2006130482A3 (en) Disposable lancet device cap with integral lancet and/or test strip and testing device utilizing the cap
WO2004066822A3 (en) Integrated lancing test strip
JP2006297103A5 (en)
WO2002100254A3 (en) Method and apparatus for lancet launching device integrated onto a blood-sampling cartridge
WO2007010087A3 (en) Health monitoring device, device modules and method
US7223248B2 (en) Packaged medical device with a deployable dermal tissue penetration member
WO2005107596A3 (en) Lancets for bodily fluid sampling supplied on a tape
WO2004034024A3 (en) Lancet system including test strips and cassettes
US20040092842A1 (en) Integrated blood sampling analysis system with multi-use sampling module
WO2003075772A3 (en) Micro-devices and analytical procedures for investigation of biological systems
WO2002078533A3 (en) Integrated sample testing meter
WO2006037646A3 (en) Integrated lancing test strip with capillary transfer sheet
ES2553251T3 (en) Diagnostic system
PL1742575T3 (en) Test magazine and method for using them
AU2002315179A1 (en) Blood sampling device with diaphragm actuated lancet
AU2002344825A1 (en) Method and apparatus for improving success rate of blood yield from a fingerstick
WO2009046957A3 (en) Analysis system for automatic skin prick analysis
JP2007521121A5 (en)
JP2009501584A5 (en)
WO2005035017A3 (en) Lancing device end cap with pressure-actuated surface features
JPWO2007063948A1 (en) Sensor-lancet integrated device and body fluid collecting method using the same
EP2315007A3 (en) Light guide test sensor for use in determining an analyte in a fluid sample and methods of manufacturing the same
NO20063798L (en) Method and apparatus for painting an analyte in a body fluid
WO2005034721A3 (en) Lancing device end cap with blood-directing contact face

Legal Events

Date Code Title Description
EEER Examination request
MKLA Lapsed

Effective date: 20220307