CA2623626A1 - Milling system - Google Patents
Milling system Download PDFInfo
- Publication number
- CA2623626A1 CA2623626A1 CA002623626A CA2623626A CA2623626A1 CA 2623626 A1 CA2623626 A1 CA 2623626A1 CA 002623626 A CA002623626 A CA 002623626A CA 2623626 A CA2623626 A CA 2623626A CA 2623626 A1 CA2623626 A1 CA 2623626A1
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- CA
- Canada
- Prior art keywords
- rotor
- milling apparatus
- sleeve
- indentations
- anyone
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
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Classifications
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- B—PERFORMING OPERATIONS; TRANSPORTING
- B02—CRUSHING, PULVERISING, OR DISINTEGRATING; PREPARATORY TREATMENT OF GRAIN FOR MILLING
- B02C—CRUSHING, PULVERISING, OR DISINTEGRATING IN GENERAL; MILLING GRAIN
- B02C17/00—Disintegrating by tumbling mills, i.e. mills having a container charged with the material to be disintegrated with or without special disintegrating members such as pebbles or balls
- B02C17/16—Mills in which a fixed container houses stirring means tumbling the charge
- B02C17/166—Mills in which a fixed container houses stirring means tumbling the charge of the annular gap type
Abstract
In order to achieve a milling apparatus which may be disposed vertically or horizontally or at any convenient angle, and in order to achieve a greater degree of efficiency the milling apparatus according to the invention comprising a radially symmetrical sleeve having an axial passageway with an upstream inlet and a downstream outlet or vice versa, a radially symmetrical rotor located within the sleeve, one of the rotor and sleeve being rotatable relative to the other, the diameter of the rotor being less than the diameter of the sleeve at each axial position to define an annular passageway between the rotor and sleeve, one or both of the surfaces of the rotor (2) and sleeve (9) having formations (4) adapted to increase the surface area encountered by particles in a fluid flow form the inlet to the outlet.
Description
MILLING SYSTEM
This invention relates to apparatus for milling or comminuting of particulate materials, particularly but not exclusively materials in liquid suspensions.
The invention also relates to apparatus for forming emulsions or finely divided inixtures of different liquids. The invention also relates to apparatus for reactive processing of materials, for example reactive mixing of polymers or monomers to produce a finely divided reactive mixture, for example on the nanometric scale.
Ball mills, bead mills and colloidal nulls are well known. These generally comprise a cylinder with smooth internal surfaces into which grinding media are placed. These mills may have internal paddles with cutting edges having various shapes and radii allowing movement of the grinding media at high speed.
According to the present invention milling apparatus comprises a radially symmetrical sleeve having an axial passageway with an upstream inlet and a downstream outlet or vice versa, a radially symmetrical rotor located within the sleeve, one of the rotor and sleeve being rotatable relative to the other, the diameter of the rotor being less than the diameter of the sleeve at each axial position to define an annular passageway between the rotor and sleeve, one or both of the surfaces of the rotor and sleeve having formations adapted to increase the surface area encountered by particles in a fluid flow from the inlet to the outlet.
The apparatus of this invention may comprise a bead mill using beads or other particulate media. Alternative embodiments not employing beads or particulate media may be used.
In a preferred embodiment the rotor is located co-axially within the sleeve.
In an alternative embodiment the axis of the rotor may be displaced parallel to the axis to the sleeve.
SUBSTITUTE SHEET (RULE 26)
This invention relates to apparatus for milling or comminuting of particulate materials, particularly but not exclusively materials in liquid suspensions.
The invention also relates to apparatus for forming emulsions or finely divided inixtures of different liquids. The invention also relates to apparatus for reactive processing of materials, for example reactive mixing of polymers or monomers to produce a finely divided reactive mixture, for example on the nanometric scale.
Ball mills, bead mills and colloidal nulls are well known. These generally comprise a cylinder with smooth internal surfaces into which grinding media are placed. These mills may have internal paddles with cutting edges having various shapes and radii allowing movement of the grinding media at high speed.
According to the present invention milling apparatus comprises a radially symmetrical sleeve having an axial passageway with an upstream inlet and a downstream outlet or vice versa, a radially symmetrical rotor located within the sleeve, one of the rotor and sleeve being rotatable relative to the other, the diameter of the rotor being less than the diameter of the sleeve at each axial position to define an annular passageway between the rotor and sleeve, one or both of the surfaces of the rotor and sleeve having formations adapted to increase the surface area encountered by particles in a fluid flow from the inlet to the outlet.
The apparatus of this invention may comprise a bead mill using beads or other particulate media. Alternative embodiments not employing beads or particulate media may be used.
In a preferred embodiment the rotor is located co-axially within the sleeve.
In an alternative embodiment the axis of the rotor may be displaced parallel to the axis to the sleeve.
SUBSTITUTE SHEET (RULE 26)
2 When beads or other grinding media are used the radial width of the annular passageway may be about twice the diameter of the beads or other particulate media.
A single size of beads or other media is preferred.
The rotor and sleeve are preferably frustoconical. Alternatively they may be concave or convex bell shaped. A frustoconical configuration is preferred.
Alternatively the rotor may be oval or elliptical in cross-section.
In preferred embodiments the diameter of the inlet is smaller than the diameter of the outlet. In alternative embodiments the diameter of the inlet is greater than the diameter of the outlet.
When the rotor is frustoconical, the apical angle may be in the range of 10-140 preferably to 20-90 Greater angles provide various benefits without increasing the length of the apparatus in comparison to a conventional mill having the same inlet diameter. A greater angle provides a greater increase in surface area from the inlet to the outlet, increasing the residence time and extent of milling as a particle passing through the system. The total volume and hence capacity of the mill is also increased.
Greater angles are preferred for high viscosity applications and for production of nanometric particles, reducing the liability of blockage on such a small scale.
Either the rotor or sleeve can rotate. Alternatively both the rotor and sleeve can rotate in opposite directions.
A further alternative the rotor and sleeve may be rotated in the same direction at different speeds. This arrangement may be employed when two or more devices in accordance with this invention are connected in series to control the rate of pumping through the apparatus.
The rate of rotation of the rotor relative to the sleeve may be 2 -3600rpm, for example 900-1600rpm.
The separation between the rotor and sleeve is preferably constant along
A single size of beads or other media is preferred.
The rotor and sleeve are preferably frustoconical. Alternatively they may be concave or convex bell shaped. A frustoconical configuration is preferred.
Alternatively the rotor may be oval or elliptical in cross-section.
In preferred embodiments the diameter of the inlet is smaller than the diameter of the outlet. In alternative embodiments the diameter of the inlet is greater than the diameter of the outlet.
When the rotor is frustoconical, the apical angle may be in the range of 10-140 preferably to 20-90 Greater angles provide various benefits without increasing the length of the apparatus in comparison to a conventional mill having the same inlet diameter. A greater angle provides a greater increase in surface area from the inlet to the outlet, increasing the residence time and extent of milling as a particle passing through the system. The total volume and hence capacity of the mill is also increased.
Greater angles are preferred for high viscosity applications and for production of nanometric particles, reducing the liability of blockage on such a small scale.
Either the rotor or sleeve can rotate. Alternatively both the rotor and sleeve can rotate in opposite directions.
A further alternative the rotor and sleeve may be rotated in the same direction at different speeds. This arrangement may be employed when two or more devices in accordance with this invention are connected in series to control the rate of pumping through the apparatus.
The rate of rotation of the rotor relative to the sleeve may be 2 -3600rpm, for example 900-1600rpm.
The separation between the rotor and sleeve is preferably constant along
3 the axis of the apparatus. A separation of 0.00001 to 200 millimetres, preferably 0.05 to 10 mm millimetres may be employed.
In further embodiment the separation between the rotor and the sleeve of the milling is of the order 0.00001 millimetres. Preferably the rotor and the sleeve of the milling system are free from indentation. The material (s) is added under pressure between the rotor and sleeve of the milling system, a pressure of 0. 1 to 2000bar poise, preferably 100 to 500bar, more preferably 1 to lObar.
Alternatively, the separation between the rotor and sleeve may be varied by locating the rotor axis a small distance from the sleeve axis to provide cavitation for high viscosity applications or in situations where no beads are employed.
An array of indentations is provided on the rotor, sleeve or both. The configuration and arrangement of the indentations and the rotor and sleeve may be the same or different in accordance with the requirements of the material to be milled.
The indentations may be arranged in a multiplicity of circular arrays disposed longitudinally along the axis of the rotor and/or sleeve, adjacent circular arrays preferably being arranged in axially offset configuration so that corresponding portions of adjacent arrays do not coincide.
In preferred embodiments the diameter of the beads or other particles is 10-2000 m, preferably 50-800 m, more preferably 50-200 m (nano-size).
The depth of the indentations is at least 4 times the diameter of the beads.
In alternative embodiments the rotor may carry the pattern or raised superficial projections. The projections are preferably arranged to form channels so as to purge the beads or particles together and also to cause rotation of the beads in use.
In a preferred embodiment 4 to 100, preferably 8 circular arrays may be provided.
In further embodiment the separation between the rotor and the sleeve of the milling is of the order 0.00001 millimetres. Preferably the rotor and the sleeve of the milling system are free from indentation. The material (s) is added under pressure between the rotor and sleeve of the milling system, a pressure of 0. 1 to 2000bar poise, preferably 100 to 500bar, more preferably 1 to lObar.
Alternatively, the separation between the rotor and sleeve may be varied by locating the rotor axis a small distance from the sleeve axis to provide cavitation for high viscosity applications or in situations where no beads are employed.
An array of indentations is provided on the rotor, sleeve or both. The configuration and arrangement of the indentations and the rotor and sleeve may be the same or different in accordance with the requirements of the material to be milled.
The indentations may be arranged in a multiplicity of circular arrays disposed longitudinally along the axis of the rotor and/or sleeve, adjacent circular arrays preferably being arranged in axially offset configuration so that corresponding portions of adjacent arrays do not coincide.
In preferred embodiments the diameter of the beads or other particles is 10-2000 m, preferably 50-800 m, more preferably 50-200 m (nano-size).
The depth of the indentations is at least 4 times the diameter of the beads.
In alternative embodiments the rotor may carry the pattern or raised superficial projections. The projections are preferably arranged to form channels so as to purge the beads or particles together and also to cause rotation of the beads in use.
In a preferred embodiment 4 to 100, preferably 8 circular arrays may be provided.
4 Each indentation may comprise a wedge shape slot, which may be generally triangular in cross-section, having a maximum depth at the leading edge relative to the direction of rotation, tapering towards the annular cavity at the trailing edge.
Alternatively each indentation may comprise a first surface extending radially inwardly from the circumference of the rotor and a tangential surface joining the inner most edge of the radial surface to form a half chordate cut out portion.
Alternatively the indentations may be curved in the longitudinal direction of the apparatus so that each indentation is trough or cup shaped with a steep surface at the leading edge and tapering at the trailing edge.
Apparatus in accordance with this invention has the advantage that liquid is pumped from the inlet to the outlet by rotation of the rotor to facilitate flow of material through the apparatus is facilitated without the need for a separate pump.
Cavitation affects during use of apparatus in accordance with this invention causes the beads to recycle and re-distribute within the chamber. This is an important benefit arising from use of indentations and apparatus in accordance with the invention. Apparatus without the indentations or projections would permit the beads to collect in the outlet preventing efficient milling.
In preferred embodiments the beads or particles occupy up to 98% of the volume of the chamber, preferably 10-95%, more preferably 75-95%.
Two or more apparatus in accordance with the present invention may be connected together so that liquid flows successively'from one to another. The larger diameter outlet of a first apparatus may be connected to the smaller diameter inlet of the following apparatus. Alternatively, the second apparatus may be connected in reverse configuration with a larger diameter inlet and smaller diameter outlet, the larger diameter portions of the adjacent apparatus being connected together.
The apparatus may also be connected to a conventional ball or bead mill.
Apparatus in this invention may be disposed vertically or horizontally or at any convenient angle. This may be contrasted to a conventional bead mill in which the affect of gravity limits the orientation in which it may be used.
Alternatively each indentation may comprise a first surface extending radially inwardly from the circumference of the rotor and a tangential surface joining the inner most edge of the radial surface to form a half chordate cut out portion.
Alternatively the indentations may be curved in the longitudinal direction of the apparatus so that each indentation is trough or cup shaped with a steep surface at the leading edge and tapering at the trailing edge.
Apparatus in accordance with this invention has the advantage that liquid is pumped from the inlet to the outlet by rotation of the rotor to facilitate flow of material through the apparatus is facilitated without the need for a separate pump.
Cavitation affects during use of apparatus in accordance with this invention causes the beads to recycle and re-distribute within the chamber. This is an important benefit arising from use of indentations and apparatus in accordance with the invention. Apparatus without the indentations or projections would permit the beads to collect in the outlet preventing efficient milling.
In preferred embodiments the beads or particles occupy up to 98% of the volume of the chamber, preferably 10-95%, more preferably 75-95%.
Two or more apparatus in accordance with the present invention may be connected together so that liquid flows successively'from one to another. The larger diameter outlet of a first apparatus may be connected to the smaller diameter inlet of the following apparatus. Alternatively, the second apparatus may be connected in reverse configuration with a larger diameter inlet and smaller diameter outlet, the larger diameter portions of the adjacent apparatus being connected together.
The apparatus may also be connected to a conventional ball or bead mill.
Apparatus in this invention may be disposed vertically or horizontally or at any convenient angle. This may be contrasted to a conventional bead mill in which the affect of gravity limits the orientation in which it may be used.
5 The apparatus may be used for processing various materials of different physical and chemical properties. High viscosity materials such as rubber or putty in which the viscosity is up to 4000 poise may be processed. Materials with a high solid content up to 95% or low solid contents below 1% may be processed by appropriate selection of the configuration of the rotor and sleeve. Particle size distribution be controlled and a greater degree of efficiency and note of milling in comparison to a conventional bead mill is observed.
An apparatus in accordance with this invention may be used in manufacture of ink, for example nano-metric ink, inkjet printers, pharmaceutical powders, ceramics, food products, agrochemicals and polymers for coatings, for example for protection clothing and body armour.
A preferred apparatus in accordance with this invention may have one or more paddles, blades or other formations on the downstream face of the rotor, adapted to urge the milled material through an outlet mesh or screen. This provides a pumping action and is particularly beneficial when handling viscose fluid materials.
The invention is further described by means of example but not in a limitative sense in reference to the accompanying drawings of which:
Figure 1 is a prospective view of a rotor of a mill in accordance with this invention;
Figure 2 is an alternative prospective view of the rotor shown in Figure 1;
Figure 3 is an end elevation of the rotor shown in Figures 1 and 2;
Figure 4 is a side elevation of the rotor;
Figure 5 is a prospective view of a rotor received within a sleeve; and
An apparatus in accordance with this invention may be used in manufacture of ink, for example nano-metric ink, inkjet printers, pharmaceutical powders, ceramics, food products, agrochemicals and polymers for coatings, for example for protection clothing and body armour.
A preferred apparatus in accordance with this invention may have one or more paddles, blades or other formations on the downstream face of the rotor, adapted to urge the milled material through an outlet mesh or screen. This provides a pumping action and is particularly beneficial when handling viscose fluid materials.
The invention is further described by means of example but not in a limitative sense in reference to the accompanying drawings of which:
Figure 1 is a prospective view of a rotor of a mill in accordance with this invention;
Figure 2 is an alternative prospective view of the rotor shown in Figure 1;
Figure 3 is an end elevation of the rotor shown in Figures 1 and 2;
Figure 4 is a side elevation of the rotor;
Figure 5 is a prospective view of a rotor received within a sleeve; and
6 Figure 6 is a cross-sectional view of the rotor and sleeve shown in Figure 5.
Figures 1 to 6 illustrate a milling apparatus in accordance with the present invention. The rotor shown in Figures 1 to 4 is generally frustoconical in shape and comprises a first end (1) having a smaller diameter than the second end (2).
The frustoconical surface of the rotor has an apical angle of 10-140 preferably 20-90 .
Axial segments (3) of the rotor define adjacent arrays of indentations (4) spaced circumferentially around each segment. Each indentation (4) comprises a radially inwardly extending surface, for example as shown at (5) in Figure 2, adjoining a tangentially extending chordate surface (6) and a radially side portion (7).
The indentation forms a right-angled cut out in the surface of the rotor.
Indentations in adjacent arrays are duly offset to provide an extended pathway for a particle passing on the length of the rotor.
The large diameter end of the rotor(2) includes four cut away portions which define an axial pump to drive fluid passing through the milling apparatus through a bead retaining mesh or screen (not shown).
Figures 5 and 6 show the rotor received in a conical sleeve (9), the sleeve having a smooth frustoconical internal surface. In use the separation between the rotor and sleeve is constant on the length of the apparatus and may range from 0.00001-200mm.
Figures 1 to 6 illustrate a milling apparatus in accordance with the present invention. The rotor shown in Figures 1 to 4 is generally frustoconical in shape and comprises a first end (1) having a smaller diameter than the second end (2).
The frustoconical surface of the rotor has an apical angle of 10-140 preferably 20-90 .
Axial segments (3) of the rotor define adjacent arrays of indentations (4) spaced circumferentially around each segment. Each indentation (4) comprises a radially inwardly extending surface, for example as shown at (5) in Figure 2, adjoining a tangentially extending chordate surface (6) and a radially side portion (7).
The indentation forms a right-angled cut out in the surface of the rotor.
Indentations in adjacent arrays are duly offset to provide an extended pathway for a particle passing on the length of the rotor.
The large diameter end of the rotor(2) includes four cut away portions which define an axial pump to drive fluid passing through the milling apparatus through a bead retaining mesh or screen (not shown).
Figures 5 and 6 show the rotor received in a conical sleeve (9), the sleeve having a smooth frustoconical internal surface. In use the separation between the rotor and sleeve is constant on the length of the apparatus and may range from 0.00001-200mm.
Claims (29)
1. A milling apparatus comprising a radially symmetrical sleeve having an axial passageway with an upstream inlet and a downstream outlet or vice versa, a radially symmetrical rotor located within the sleeve, one of the rotor and sleeve being rotatable relative to the other, the diameter of the rotor being less than the diameter of the sleeve at each axial position to define an annular passageway between the rotor and sleeve, one or both of the surfaces of the rotor and sleeve having formations adapted to increase the surface area encountered by particles in a fluid flow from the inlet to the outlet.
2. A milling apparatus as claimed in claim 1, comprising a bead mill using beads or other particulate media.
3. A milling apparatus as claimed in either of claims 1 or 2 wherein the rotor is located co-axially with the sleeve.
4. A milling apparatus as claimed in either of claims 1 or 2, wherein the axis for the rotor is displaced parallel to the axis of the sleeve.
5. A milling apparatus as claimed in any one of claims 1 to 4, wherein the rotor and the sleeve are frustoconical.
6. A milling apparatus as claimed in any one of claims 1 to 4, wherein the rotor and sleeve are oval or elliptical in cross section.
7. A milling apparatus as claimed in any one of claims 1 to 4, wherein the rotor is oval or elliptical in cross Section-8. A milling apparatus as claimed in any one of claims 1 to 7, wherein the diameter of the inlet is smaller than the diameter of the outlet.
8. A milling apparatus as claimed in any one of claims 1 to 7, wherein the diameter of the inlet is greater than the diameter of the outlet.
9. A milling apparatus as claimed in anyone of claims 1 to 4, wherein the rotor is frustoconical and the apical angle is in the range of 10 - 140°, preferably 20 -90°.
10. A milling apparatus as claimed in any one of claims 1 to 9, wherein at least one of the sleeve and rotor is free to rotate, preferably both the sleeve and rotor are free to rotate.
11. A milling apparatus as claimed in anyone of claims 1 to 9, wherein the sleeve and rotor are free to rotate in opposite directions.
12. A milling apparatus as claimed in anyone of claims 1 to 9, wherein the sleeve and rotor are adapted to rotate in the same direction at different speeds.
13. A milling apparatus as claimed in anyone of claims 1 to 12, wherein the rate of rotation of the rotor relative to the sleeve is in the range of 300-3600 rpm, preferably 900-1600 rpm.
14. A milling apparatus as claimed in anyone of claims 1 to 13 wherein the separation between rotor and sleeve is constant along the axis of the apparatus, the separation preferably being in the range 0.01 mm to 90mm, more preferably in the range of 0-05 to 1 mm.
15. A milling apparatus as claimed in any one of claims 1 to 14, wherein at least one of the rotor and sleeve comprises an array of indentations.
16. A milling apparatus as claimed in claim 15, wherein both the rotor and sleeve comprise an array of indentations.
17. A milling apparatus as claimed in claim 16, wherein the arrangement of indentations on the rotor and sleeve are the same.
18. A milling apparatus as claimed in claim 16 wherein the arrangement of indentations on the rotor and sleeve are different.
19. A milling apparatus as claimed in anyone of claims 15 to 18, wherein at least one array of indentations comprises a plurality of adjacent circular arrays, the arrays preferably being arranged in axially offset configuration such that corresponding portions of adjacent circular arrays do not coincide.
22. A milling apparatus as claimed in claim 19, wherein the array of indentations comprises between 4 and 100 circular arrays, preferably 8 circular arrays.
21. A milling apparatus as claimed in any one of claims 15 to 20, wherein at least some of the indentations comprise a wedge shaped slot.
22. A milling apparatus as claimed in claim 21, wherein the indentation is generally triangular in cross section.
23. A milling apparatus as claimed in either of claims 21 or 22, wherein the maximum depth of the indentation is at the leading edge of the indentation relative to the direction of rotation, tapering towards an annular cavity at the trailing edge.
24. A milling apparatus as claimed in anyone of claims 15 to 23, wherein at least some of the indentations comprise a first surface extending radially inwardly from the circumference of the rotor and a tangential surface joining the inner most edge of the radial surface to form a half chordate cut out portion.
25. A milling apparatus as claimed in anyone of claims 15 to 24, wherein at least some of the indentations are curved in the longitudinal direction of the apparatus such that each of the indentations is trough or cup shaped with a steep surface at the leading edge and tapering at the trailing edge.
26. A milling apparatus as claimed in anyone of claims 1 to 25, wherein the rotor may comprise one or more formations on the downstream face of the rotor adapted to urge the milled material through an outlet mesh or screen.
27. A milling apparatus as claimed in any one of claims 1 to 26, wherein the rotor carries a pattern of raised superficial projections. The projections preferably being arranged to form channels.
28. A combined milling apparatus comprising first and second milling apparatus as claimed in any one of claims 1 to 27, wherein the outlet of the first milling apparatus is connected to the inlet of the second milling apparatus.
29. A milling apparatus as claimed in any one of claims 1 to 28, wherein the material to be milled is added between rotor and sleeve under pressure, preferably with the pressure being in the ranges of 10 to 20,000 psi, preferably 1,000 to 5,000 psi, more preferably 100 to 1,000 psi.
Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| GB0516549.3 | 2005-08-12 | ||
| GBGB0516549.3A GB0516549D0 (en) | 2005-08-12 | 2005-08-12 | Milling system |
| PCT/GB2006/003017 WO2007020407A2 (en) | 2005-08-12 | 2006-08-14 | The milling system |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| CA2623626A1 true CA2623626A1 (en) | 2007-02-22 |
| CA2623626C CA2623626C (en) | 2016-05-17 |
Family
ID=35098184
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| CA2623626A Active CA2623626C (en) | 2005-08-12 | 2006-08-14 | Milling system |
Country Status (6)
| Country | Link |
|---|---|
| US (1) | US7857247B2 (en) |
| EP (1) | EP1940553A2 (en) |
| CN (1) | CN101277766B (en) |
| CA (1) | CA2623626C (en) |
| GB (1) | GB0516549D0 (en) |
| WO (1) | WO2007020407A2 (en) |
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| US8313051B2 (en) * | 2008-03-05 | 2012-11-20 | Sealed Air Corporation (Us) | Process and apparatus for mixing a polymer composition and composite polymers resulting therefrom |
| GB201102237D0 (en) | 2011-02-09 | 2011-03-23 | Kuecept Ltd | Particle formulation |
| GB201307659D0 (en) | 2013-04-26 | 2013-06-12 | Korea Coast Guard Commissioner | Preparation of drug particles by micronisation |
| US9393202B2 (en) | 2013-04-26 | 2016-07-19 | Chiesi Farmaceutici S.P.A | Particle size reduction of an antimuscarinic compound |
| CN104414509B (en) * | 2013-09-04 | 2017-05-31 | 李致纬 | A kind of pulverizing blade member |
| CN104414508B (en) * | 2013-09-04 | 2017-08-11 | 李致纬 | A kind of macerator pump |
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| US5510118A (en) | 1995-02-14 | 1996-04-23 | Nanosystems Llc | Process for preparing therapeutic compositions containing nanoparticles |
| US5704556A (en) | 1995-06-07 | 1998-01-06 | Mclaughlin; John R. | Process for rapid production of colloidal particles |
| AU6546496A (en) | 1995-07-26 | 1997-02-26 | Nanosystems L.L.C. | Methacrylate backbone surfactants in nanoparticulate formulations |
| CN1182816A (en) * | 1996-11-15 | 1998-05-27 | 刘忠文 | Machine for cutting paper into pieces capable of separating waste paper and coated film |
| DE19925184A1 (en) | 1999-05-26 | 2000-11-30 | Schering Ag | Continuous process for the production of morphologically uniform micro and nanoparticles by means of a micromixer as well as particles produced by this process |
| GB9920148D0 (en) | 1999-08-25 | 1999-10-27 | Smithkline Beecham Plc | Novel composition |
| DE102005018400B4 (en) | 2005-04-20 | 2014-10-16 | VDZ gGmbH | grinder |
| JP5392199B2 (en) | 2010-07-09 | 2014-01-22 | ソニー株式会社 | Image processing apparatus and method |
-
2005
- 2005-08-12 GB GBGB0516549.3A patent/GB0516549D0/en not_active Ceased
-
2006
- 2006-08-14 CA CA2623626A patent/CA2623626C/en active Active
- 2006-08-14 WO PCT/GB2006/003017 patent/WO2007020407A2/en active Application Filing
- 2006-08-14 US US11/991,804 patent/US7857247B2/en not_active Expired - Fee Related
- 2006-08-14 CN CN2006800367635A patent/CN101277766B/en not_active Expired - Fee Related
- 2006-08-14 EP EP06794539A patent/EP1940553A2/en not_active Withdrawn
Also Published As
| Publication number | Publication date |
|---|---|
| US20080251617A1 (en) | 2008-10-16 |
| US7857247B2 (en) | 2010-12-28 |
| EP1940553A2 (en) | 2008-07-09 |
| GB0516549D0 (en) | 2005-09-21 |
| CA2623626C (en) | 2016-05-17 |
| CN101277766A (en) | 2008-10-01 |
| CN101277766B (en) | 2011-09-14 |
| WO2007020407A2 (en) | 2007-02-22 |
| WO2007020407A3 (en) | 2007-07-12 |
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