CA2676595A1 - Containers intended for moisture-sensitive products - Google Patents

Containers intended for moisture-sensitive products Download PDF

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Publication number
CA2676595A1
CA2676595A1 CA002676595A CA2676595A CA2676595A1 CA 2676595 A1 CA2676595 A1 CA 2676595A1 CA 002676595 A CA002676595 A CA 002676595A CA 2676595 A CA2676595 A CA 2676595A CA 2676595 A1 CA2676595 A1 CA 2676595A1
Authority
CA
Canada
Prior art keywords
desiccant
polymeric material
container
inner layer
layer
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Granted
Application number
CA002676595A
Other languages
French (fr)
Other versions
CA2676595C (en
Inventor
Rick Merical
Kenneth Charles Wurtzel
Lee Murray
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Amcor Pharmaceutical Packaging USA Inc
Original Assignee
Alcan Global Pharmaceutical Packaging Inc.
Rick Merical
Kenneth Charles Wurtzel
Lee Murray
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Priority claimed from US11/670,801 external-priority patent/US8110260B2/en
Application filed by Alcan Global Pharmaceutical Packaging Inc., Rick Merical, Kenneth Charles Wurtzel, Lee Murray filed Critical Alcan Global Pharmaceutical Packaging Inc.
Publication of CA2676595A1 publication Critical patent/CA2676595A1/en
Application granted granted Critical
Publication of CA2676595C publication Critical patent/CA2676595C/en
Active legal-status Critical Current
Anticipated expiration legal-status Critical

Links

Classifications

    • BPERFORMING OPERATIONS; TRANSPORTING
    • B29WORKING OF PLASTICS; WORKING OF SUBSTANCES IN A PLASTIC STATE IN GENERAL
    • B29CSHAPING OR JOINING OF PLASTICS; SHAPING OF MATERIAL IN A PLASTIC STATE, NOT OTHERWISE PROVIDED FOR; AFTER-TREATMENT OF THE SHAPED PRODUCTS, e.g. REPAIRING
    • B29C45/00Injection moulding, i.e. forcing the required volume of moulding material through a nozzle into a closed mould; Apparatus therefor
    • B29C45/16Making multilayered or multicoloured articles
    • B29C45/1642Making multilayered or multicoloured articles having a "sandwich" structure
    • B29C45/1646Injecting parison-like articles
    • BPERFORMING OPERATIONS; TRANSPORTING
    • B29WORKING OF PLASTICS; WORKING OF SUBSTANCES IN A PLASTIC STATE IN GENERAL
    • B29CSHAPING OR JOINING OF PLASTICS; SHAPING OF MATERIAL IN A PLASTIC STATE, NOT OTHERWISE PROVIDED FOR; AFTER-TREATMENT OF THE SHAPED PRODUCTS, e.g. REPAIRING
    • B29C49/00Blow-moulding, i.e. blowing a preform or parison to a desired shape within a mould; Apparatus therefor
    • B29C49/0005Blow-moulding, i.e. blowing a preform or parison to a desired shape within a mould; Apparatus therefor characterised by the material
    • BPERFORMING OPERATIONS; TRANSPORTING
    • B32LAYERED PRODUCTS
    • B32BLAYERED PRODUCTS, i.e. PRODUCTS BUILT-UP OF STRATA OF FLAT OR NON-FLAT, e.g. CELLULAR OR HONEYCOMB, FORM
    • B32B27/00Layered products comprising a layer of synthetic resin
    • B32B27/18Layered products comprising a layer of synthetic resin characterised by the use of special additives
    • BPERFORMING OPERATIONS; TRANSPORTING
    • B32LAYERED PRODUCTS
    • B32BLAYERED PRODUCTS, i.e. PRODUCTS BUILT-UP OF STRATA OF FLAT OR NON-FLAT, e.g. CELLULAR OR HONEYCOMB, FORM
    • B32B27/00Layered products comprising a layer of synthetic resin
    • B32B27/32Layered products comprising a layer of synthetic resin comprising polyolefins
    • BPERFORMING OPERATIONS; TRANSPORTING
    • B32LAYERED PRODUCTS
    • B32BLAYERED PRODUCTS, i.e. PRODUCTS BUILT-UP OF STRATA OF FLAT OR NON-FLAT, e.g. CELLULAR OR HONEYCOMB, FORM
    • B32B33/00Layered products characterised by particular properties or particular surface features, e.g. particular surface coatings; Layered products designed for particular purposes not covered by another single class
    • BPERFORMING OPERATIONS; TRANSPORTING
    • B65CONVEYING; PACKING; STORING; HANDLING THIN OR FILAMENTARY MATERIAL
    • B65DCONTAINERS FOR STORAGE OR TRANSPORT OF ARTICLES OR MATERIALS, e.g. BAGS, BARRELS, BOTTLES, BOXES, CANS, CARTONS, CRATES, DRUMS, JARS, TANKS, HOPPERS, FORWARDING CONTAINERS; ACCESSORIES, CLOSURES, OR FITTINGS THEREFOR; PACKAGING ELEMENTS; PACKAGES
    • B65D1/00Containers having bodies formed in one piece, e.g. by casting metallic material, by moulding plastics, by blowing vitreous material, by throwing ceramic material, by moulding pulped fibrous material, by deep-drawing operations performed on sheet material
    • B65D1/02Bottles or similar containers with necks or like restricted apertures, designed for pouring contents
    • B65D1/0207Bottles or similar containers with necks or like restricted apertures, designed for pouring contents characterised by material, e.g. composition, physical features
    • B65D1/0215Bottles or similar containers with necks or like restricted apertures, designed for pouring contents characterised by material, e.g. composition, physical features multilayered
    • BPERFORMING OPERATIONS; TRANSPORTING
    • B65CONVEYING; PACKING; STORING; HANDLING THIN OR FILAMENTARY MATERIAL
    • B65DCONTAINERS FOR STORAGE OR TRANSPORT OF ARTICLES OR MATERIALS, e.g. BAGS, BARRELS, BOTTLES, BOXES, CANS, CARTONS, CRATES, DRUMS, JARS, TANKS, HOPPERS, FORWARDING CONTAINERS; ACCESSORIES, CLOSURES, OR FITTINGS THEREFOR; PACKAGING ELEMENTS; PACKAGES
    • B65D81/00Containers, packaging elements, or packages, for contents presenting particular transport or storage problems, or adapted to be used for non-packaging purposes after removal of contents
    • B65D81/24Adaptations for preventing deterioration or decay of contents; Applications to the container or packaging material of food preservatives, fungicides, pesticides or animal repellants
    • B65D81/26Adaptations for preventing deterioration or decay of contents; Applications to the container or packaging material of food preservatives, fungicides, pesticides or animal repellants with provision for draining away, or absorbing, or removing by ventilation, fluids, e.g. exuded by contents; Applications of corrosion inhibitors or desiccators
    • B65D81/266Adaptations for preventing deterioration or decay of contents; Applications to the container or packaging material of food preservatives, fungicides, pesticides or animal repellants with provision for draining away, or absorbing, or removing by ventilation, fluids, e.g. exuded by contents; Applications of corrosion inhibitors or desiccators for absorbing gases, e.g. oxygen absorbers or desiccants
    • BPERFORMING OPERATIONS; TRANSPORTING
    • B29WORKING OF PLASTICS; WORKING OF SUBSTANCES IN A PLASTIC STATE IN GENERAL
    • B29CSHAPING OR JOINING OF PLASTICS; SHAPING OF MATERIAL IN A PLASTIC STATE, NOT OTHERWISE PROVIDED FOR; AFTER-TREATMENT OF THE SHAPED PRODUCTS, e.g. REPAIRING
    • B29C2949/00Indexing scheme relating to blow-moulding
    • B29C2949/07Preforms or parisons characterised by their configuration
    • B29C2949/0715Preforms or parisons characterised by their configuration the preform having one end closed
    • BPERFORMING OPERATIONS; TRANSPORTING
    • B29WORKING OF PLASTICS; WORKING OF SUBSTANCES IN A PLASTIC STATE IN GENERAL
    • B29CSHAPING OR JOINING OF PLASTICS; SHAPING OF MATERIAL IN A PLASTIC STATE, NOT OTHERWISE PROVIDED FOR; AFTER-TREATMENT OF THE SHAPED PRODUCTS, e.g. REPAIRING
    • B29C2949/00Indexing scheme relating to blow-moulding
    • B29C2949/30Preforms or parisons made of several components
    • B29C2949/3008Preforms or parisons made of several components at neck portion
    • BPERFORMING OPERATIONS; TRANSPORTING
    • B29WORKING OF PLASTICS; WORKING OF SUBSTANCES IN A PLASTIC STATE IN GENERAL
    • B29CSHAPING OR JOINING OF PLASTICS; SHAPING OF MATERIAL IN A PLASTIC STATE, NOT OTHERWISE PROVIDED FOR; AFTER-TREATMENT OF THE SHAPED PRODUCTS, e.g. REPAIRING
    • B29C2949/00Indexing scheme relating to blow-moulding
    • B29C2949/30Preforms or parisons made of several components
    • B29C2949/3012Preforms or parisons made of several components at flange portion
    • BPERFORMING OPERATIONS; TRANSPORTING
    • B29WORKING OF PLASTICS; WORKING OF SUBSTANCES IN A PLASTIC STATE IN GENERAL
    • B29CSHAPING OR JOINING OF PLASTICS; SHAPING OF MATERIAL IN A PLASTIC STATE, NOT OTHERWISE PROVIDED FOR; AFTER-TREATMENT OF THE SHAPED PRODUCTS, e.g. REPAIRING
    • B29C2949/00Indexing scheme relating to blow-moulding
    • B29C2949/30Preforms or parisons made of several components
    • B29C2949/3016Preforms or parisons made of several components at body portion
    • BPERFORMING OPERATIONS; TRANSPORTING
    • B29WORKING OF PLASTICS; WORKING OF SUBSTANCES IN A PLASTIC STATE IN GENERAL
    • B29CSHAPING OR JOINING OF PLASTICS; SHAPING OF MATERIAL IN A PLASTIC STATE, NOT OTHERWISE PROVIDED FOR; AFTER-TREATMENT OF THE SHAPED PRODUCTS, e.g. REPAIRING
    • B29C2949/00Indexing scheme relating to blow-moulding
    • B29C2949/30Preforms or parisons made of several components
    • B29C2949/302Preforms or parisons made of several components at bottom portion
    • BPERFORMING OPERATIONS; TRANSPORTING
    • B29WORKING OF PLASTICS; WORKING OF SUBSTANCES IN A PLASTIC STATE IN GENERAL
    • B29CSHAPING OR JOINING OF PLASTICS; SHAPING OF MATERIAL IN A PLASTIC STATE, NOT OTHERWISE PROVIDED FOR; AFTER-TREATMENT OF THE SHAPED PRODUCTS, e.g. REPAIRING
    • B29C2949/00Indexing scheme relating to blow-moulding
    • B29C2949/30Preforms or parisons made of several components
    • B29C2949/3024Preforms or parisons made of several components characterised by the number of components or by the manufacturing technique
    • B29C2949/3026Preforms or parisons made of several components characterised by the number of components or by the manufacturing technique having two or more components
    • BPERFORMING OPERATIONS; TRANSPORTING
    • B29WORKING OF PLASTICS; WORKING OF SUBSTANCES IN A PLASTIC STATE IN GENERAL
    • B29CSHAPING OR JOINING OF PLASTICS; SHAPING OF MATERIAL IN A PLASTIC STATE, NOT OTHERWISE PROVIDED FOR; AFTER-TREATMENT OF THE SHAPED PRODUCTS, e.g. REPAIRING
    • B29C2949/00Indexing scheme relating to blow-moulding
    • B29C2949/30Preforms or parisons made of several components
    • B29C2949/3024Preforms or parisons made of several components characterised by the number of components or by the manufacturing technique
    • B29C2949/3026Preforms or parisons made of several components characterised by the number of components or by the manufacturing technique having two or more components
    • B29C2949/3028Preforms or parisons made of several components characterised by the number of components or by the manufacturing technique having two or more components having three or more components
    • BPERFORMING OPERATIONS; TRANSPORTING
    • B29WORKING OF PLASTICS; WORKING OF SUBSTANCES IN A PLASTIC STATE IN GENERAL
    • B29CSHAPING OR JOINING OF PLASTICS; SHAPING OF MATERIAL IN A PLASTIC STATE, NOT OTHERWISE PROVIDED FOR; AFTER-TREATMENT OF THE SHAPED PRODUCTS, e.g. REPAIRING
    • B29C2949/00Indexing scheme relating to blow-moulding
    • B29C2949/30Preforms or parisons made of several components
    • B29C2949/3032Preforms or parisons made of several components having components being injected
    • BPERFORMING OPERATIONS; TRANSPORTING
    • B29WORKING OF PLASTICS; WORKING OF SUBSTANCES IN A PLASTIC STATE IN GENERAL
    • B29CSHAPING OR JOINING OF PLASTICS; SHAPING OF MATERIAL IN A PLASTIC STATE, NOT OTHERWISE PROVIDED FOR; AFTER-TREATMENT OF THE SHAPED PRODUCTS, e.g. REPAIRING
    • B29C2949/00Indexing scheme relating to blow-moulding
    • B29C2949/30Preforms or parisons made of several components
    • B29C2949/3032Preforms or parisons made of several components having components being injected
    • B29C2949/3034Preforms or parisons made of several components having components being injected having two or more components being injected
    • BPERFORMING OPERATIONS; TRANSPORTING
    • B29WORKING OF PLASTICS; WORKING OF SUBSTANCES IN A PLASTIC STATE IN GENERAL
    • B29CSHAPING OR JOINING OF PLASTICS; SHAPING OF MATERIAL IN A PLASTIC STATE, NOT OTHERWISE PROVIDED FOR; AFTER-TREATMENT OF THE SHAPED PRODUCTS, e.g. REPAIRING
    • B29C2949/00Indexing scheme relating to blow-moulding
    • B29C2949/30Preforms or parisons made of several components
    • B29C2949/3032Preforms or parisons made of several components having components being injected
    • B29C2949/3034Preforms or parisons made of several components having components being injected having two or more components being injected
    • B29C2949/3036Preforms or parisons made of several components having components being injected having two or more components being injected having three or more components being injected
    • BPERFORMING OPERATIONS; TRANSPORTING
    • B29WORKING OF PLASTICS; WORKING OF SUBSTANCES IN A PLASTIC STATE IN GENERAL
    • B29CSHAPING OR JOINING OF PLASTICS; SHAPING OF MATERIAL IN A PLASTIC STATE, NOT OTHERWISE PROVIDED FOR; AFTER-TREATMENT OF THE SHAPED PRODUCTS, e.g. REPAIRING
    • B29C2949/00Indexing scheme relating to blow-moulding
    • B29C2949/30Preforms or parisons made of several components
    • B29C2949/3041Preforms or parisons made of several components having components being extruded
    • B29C2949/3042Preforms or parisons made of several components having components being extruded having two or more components being extruded
    • BPERFORMING OPERATIONS; TRANSPORTING
    • B29WORKING OF PLASTICS; WORKING OF SUBSTANCES IN A PLASTIC STATE IN GENERAL
    • B29CSHAPING OR JOINING OF PLASTICS; SHAPING OF MATERIAL IN A PLASTIC STATE, NOT OTHERWISE PROVIDED FOR; AFTER-TREATMENT OF THE SHAPED PRODUCTS, e.g. REPAIRING
    • B29C2949/00Indexing scheme relating to blow-moulding
    • B29C2949/30Preforms or parisons made of several components
    • B29C2949/3041Preforms or parisons made of several components having components being extruded
    • B29C2949/3042Preforms or parisons made of several components having components being extruded having two or more components being extruded
    • B29C2949/3044Preforms or parisons made of several components having components being extruded having two or more components being extruded having three or more components being extruded
    • BPERFORMING OPERATIONS; TRANSPORTING
    • B29WORKING OF PLASTICS; WORKING OF SUBSTANCES IN A PLASTIC STATE IN GENERAL
    • B29CSHAPING OR JOINING OF PLASTICS; SHAPING OF MATERIAL IN A PLASTIC STATE, NOT OTHERWISE PROVIDED FOR; AFTER-TREATMENT OF THE SHAPED PRODUCTS, e.g. REPAIRING
    • B29C49/00Blow-moulding, i.e. blowing a preform or parison to a desired shape within a mould; Apparatus therefor
    • B29C49/02Combined blow-moulding and manufacture of the preform or the parison
    • B29C49/04Extrusion blow-moulding
    • BPERFORMING OPERATIONS; TRANSPORTING
    • B29WORKING OF PLASTICS; WORKING OF SUBSTANCES IN A PLASTIC STATE IN GENERAL
    • B29CSHAPING OR JOINING OF PLASTICS; SHAPING OF MATERIAL IN A PLASTIC STATE, NOT OTHERWISE PROVIDED FOR; AFTER-TREATMENT OF THE SHAPED PRODUCTS, e.g. REPAIRING
    • B29C49/00Blow-moulding, i.e. blowing a preform or parison to a desired shape within a mould; Apparatus therefor
    • B29C49/02Combined blow-moulding and manufacture of the preform or the parison
    • B29C49/06Injection blow-moulding
    • BPERFORMING OPERATIONS; TRANSPORTING
    • B29WORKING OF PLASTICS; WORKING OF SUBSTANCES IN A PLASTIC STATE IN GENERAL
    • B29CSHAPING OR JOINING OF PLASTICS; SHAPING OF MATERIAL IN A PLASTIC STATE, NOT OTHERWISE PROVIDED FOR; AFTER-TREATMENT OF THE SHAPED PRODUCTS, e.g. REPAIRING
    • B29C49/00Blow-moulding, i.e. blowing a preform or parison to a desired shape within a mould; Apparatus therefor
    • B29C49/22Blow-moulding, i.e. blowing a preform or parison to a desired shape within a mould; Apparatus therefor using multilayered preforms or parisons
    • BPERFORMING OPERATIONS; TRANSPORTING
    • B29WORKING OF PLASTICS; WORKING OF SUBSTANCES IN A PLASTIC STATE IN GENERAL
    • B29KINDEXING SCHEME ASSOCIATED WITH SUBCLASSES B29B, B29C OR B29D, RELATING TO MOULDING MATERIALS OR TO MATERIALS FOR MOULDS, REINFORCEMENTS, FILLERS OR PREFORMED PARTS, e.g. INSERTS
    • B29K2105/00Condition, form or state of moulded material or of the material to be shaped
    • B29K2105/0005Condition, form or state of moulded material or of the material to be shaped containing compounding ingredients
    • BPERFORMING OPERATIONS; TRANSPORTING
    • B32LAYERED PRODUCTS
    • B32BLAYERED PRODUCTS, i.e. PRODUCTS BUILT-UP OF STRATA OF FLAT OR NON-FLAT, e.g. CELLULAR OR HONEYCOMB, FORM
    • B32B2439/00Containers; Receptacles
    • B32B2439/40Closed containers

Abstract

A container for a moisture-sensitive product. The container has an openable container body defining an interior volume for holding the product. More specifically, a rigid container defining an interior volume for holding a moisture-sensitive product, and comprising at least an inner layer and an outer layer, the inner and outer layers being coextruded layers, the inner layer comprising a polymeric material and a desiccant material, the outer layer comprising a moisture-barrier material.

Claims (43)

1. A method for making a multilayer container, comprising:

providing a first masterbatch comprising calcium oxide and a first polymeric material;
providing a second masterbatch comprising a physical desiccant and a second polymeric material;

blending the first masterbatch and the second masterbatch with a third polymeric material to form a subsequent blend;

forming the subsequent blend and high density polyethylene into a preform via coextrusion or via coinjection molding; and blow-molding the preform to form the container.
2. The method of claim 1, wherein the calcium oxide is present at a range of from about 20 to about 60 weight percent of the subsequent blend and the physical desiccant is present at a range from about 1 to about 20 weight percent of the subsequent blend.
3. The method of claim 1, wherein the step of blending further comprises blending a blowing agent with the first masterbatch, the second masterbatch and the third polymeric material.
4. The method of claim 1, wherein the first polymeric material and the second polymeric material are the same polymeric material.
5. The method of claim 1, wherein the step of forming comprises forming a shape selected from the group consisting of a bottle, a vial, and a formed sheet with lidstock.
6. The method of claim 1, wherein the step of forming further comprises including a barrier layer between the subsequent blend and the high density polyethylene.
7. The method of claim 1, wherein the step of forming further comprises including a desiccant layer between the subsequent blend and the high density polyethylene,
8. The method of claim 7, wherein the desiccant layer comprises calcium oxide.
9. A method for making a multilayer component, comprising:

providing a first masterbatch comprising calcium oxide and a first polymeric material;

providing a second masterbatch comprising a physical desiccant and a second polymeric material;

blending the first masterbatch and the second masterbatch with a third polymeric material to form a subsequent blend;

forming the subsequent blend and high density polyethylene or polypropylene into the component via coinjection molding.
10. The method of claim 9, wherein the step of forming further comprises including a barrier layer between the subsequent blend and the high density polyethylene or polypropylene.
11. The method of claim 10, wherein the barrier layer comprises a material selected from the group consisting of polyvinylidene chloride, ethylene vinyl alcohol, a fluoropolymer resin and polychlorotrifluoro ethylene.
12. A method for making a multilayer container, comprising:

providing a first masterbatch comprising a first desiccant material and a first polymeric material;

providing a second masterbatch comprising a second desiccant material and a second polymeric material;

blending the first masterbatch and the second masterbatch with a third polymeric material to form a subsequent blend;

forming the subsequent blend and a fourth polymeric material into the container using a process selected from the group consisting of coextrusion blow molding, coinjection molding, coinjection blow molding and coinjection stretch molding.
13. The method of claim 12, wherein the first desiccant material comprises calcium oxide.
14. The method of claim 13, wherein the calcium oxide is present at a range of from about 20 to about 60 weight percent of the subsequent blend.
15. The method of claim 12, wherein the second desiccant material comprises one or more molecular sieves.
16. The method of claim 12, wherein the step of forming further comprises including a desiccant layer between the subsequent blend and the fourth polymeric material.
17. The method of claim 16, wherein the desiccant layer comprises a chemical desiccant material.
18. The method of claim 12, wherein the first polymeric material is selected from the group consisting of linear low density polyethylene, low density polyethylene, medium density polyethylene, high density polyethylene, polyethylene, polypropylene homopolymers, polypropylene copolymers, polyethylene naphthalate, cellulose acetate butyrate, ethyl cellulose, polycarbonate, nylon, polysulfone, polyether sulfone, cyclic olefin homopolymers and cyclic olefin copolymers.
19. The method of claim 12, wherein the second polymeric material is selected from the group consisting of linear low density polyethylene, high density polyethylene, polypropylene, medium density polyethylene, low density polyethylene, cyclic olefins cyclic olefin copolymers, polycarbonate, nylon, polyethylene naphthalate and polyethylene terephthalate.
20. A container defining an interior volume for holding a moisture-sensitive product, and comprising at least an inner layer and an outer layer, the inner and outer layers being formed by a process selected from the group consisting of coextrusion blow molding, coinjection molding, coinjection blow molding and coinjection stretch blow molding, the inner layer comprising a polymeric material and a desiccant material, the outer layer comprising a moisture-barrier material.
21. A container according to claim 20, wherein the inner layer has a porous structure.
22. A container according to claim 20, wherein the outer layer has a non-porous structure.
23. A container according to claim 20, further comprising an intermediate layer positioned between the inner layer and the outer layer, the intermediate layer comprising a material having a higher moisture resistance than the moisture-barrier material in the outer layer.
24. A container according to claim 20, wherein the desiccant material is a chemical desiccant.
25. A container according to claim 20, wherein the desiccant material is physical desiccant.
26. A container according to claim 20, wherein the desiccant material is a blend of chemical and physical desiccants.
27. A container according to claim 24, wherein said chemical desiccant is calcium oxide.
28. A container according to claim 20, wherein the polymeric material of the inner layer and the moisture-barrier material of the outer layer are the same materials.
29. A container according to claim 20, wherein the polymeric material of the inner layer and the moisture-barrier material of the outer layer are different materials.
30. A container according to claim 20, wherein the polymeric material of the inner layer is selected from the group consisting of high density polyethylenes, cyclic olefin copolymers, polyethylenes, polypropylenes, nylons and polyesters.
31. A container according to claim 20, wherein the moisture barrier material of the outer layer is selected from the group consisting of fluoropolymer resins and polychlorotrifluoroethylene.
32. A container according to claim 20, wherein the inner layer is formed using a blowing agent.
33. A container according to claim 20, wherein the inner layer comprises a molecular sieve.
34. A container according to claim 20, wherein the inner layer comprises a blend of a molecular sieve and calcium oxide.
35. A container and closure combination comprising rigid container and a closure, the rigid container defining an interior volume for holding a moisture-sensitive product and a defining an opening adjacent the interior volume, the rigid container comprising at least an inner layer and an outer layer, the inner and outer layers being coextruded layers, the inner layer comprising a polymeric material and a desiccant material, the outer layer comprising a moisture-barrier material, the closure adapted to close the opening.
36. A container and closure combination according to claim 35, wherein the ratio of desiccant to polymeric material in the inner layer is in the range of approximately 5 parts by weight of desiccant to 95 parts by weight polymeric material, to 80 parts by weight of desiccant to 20 parts by weight polymeric material.
37. A container and closure combination according to claim 36, wherein the ratio of desiccant to polymeric material is approximately 10-25 parts by weight desiccant to approximately 75-90 parts by weight polymeric material.
38. A container and closure combination according to claim 36, wherein the ratio of desiccant to polymeric material is approximately 50:50 by weight.
39. A container defining an interior volume for holding a moisture-sensitive product, and comprising at least an inner layer and an outer layer, the inner and outer layers being coextruded layers, the inner layer comprising a polymeric material and a desiccant material, the outer layer comprising a moisture-barrier material, wherein the ratio of desiccant to polymeric material in the inner layer is in the range of approximately 5 parts by weight of desiccant to 95 parts by weight polymeric material, to 80 parts by weight of desiccant to 20 parts by weight polymeric material.
40. A container according to claim 39, wherein the ratio of desiccant to polymeric material is approximately 10-25 parts by weight desiccant to approximately 75-90 parts by weight polymeric material.
41. A container according to claim 39, wherein the ratio of desiccant to polymeric material is approximately 50:50 by weight.
42. A method for making a container comprising the steps of:
adding a desiccant to a polymeric material to form a mixture;

forming the container comprising an inner layer and an outer layer using a process selected from the group consisting of coextrusion blow molding, coinjection molding, coinjection blow molding and coinjection stretch blow molding, wherein the inner layer comprises the mixture of desiccant and polymeric material, and the outer layer comprises a moisture-barrier material.
43. The method of claim 42 further comprising the step of using a blowing agent to form a porous structure in the inner layer.
CA2676595A 2007-02-02 2008-02-01 Containers intended for moisture-sensitive products Active CA2676595C (en)

Applications Claiming Priority (5)

Application Number Priority Date Filing Date Title
US11/670,801 2007-02-02
US11/670,801 US8110260B2 (en) 2007-02-02 2007-02-02 Containers intended for moisture-sensitive products
US11/829,280 US7871558B2 (en) 2002-06-20 2007-07-27 Containers intended for moisture-sensitive products
US11/829,280 2007-07-27
PCT/US2008/052767 WO2008097830A1 (en) 2007-02-02 2008-02-01 Containers intended for moisture-sensitive products

Publications (2)

Publication Number Publication Date
CA2676595A1 true CA2676595A1 (en) 2008-08-14
CA2676595C CA2676595C (en) 2013-01-08

Family

ID=38948439

Family Applications (1)

Application Number Title Priority Date Filing Date
CA2676595A Active CA2676595C (en) 2007-02-02 2008-02-01 Containers intended for moisture-sensitive products

Country Status (7)

Country Link
US (1) US7871558B2 (en)
EP (1) EP2121313A1 (en)
JP (1) JP2010517880A (en)
CA (1) CA2676595C (en)
IL (1) IL199968A0 (en)
MX (1) MX2009008142A (en)
WO (1) WO2008097830A1 (en)

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ATE539769T1 (en) * 2008-03-04 2012-01-15 Lupin Ltd STABLE PHARMACEUTICAL COMPOSITIONS CONTAINING CARVEDILOL
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