CA2782385A1

CA2782385A1 - Modular endograft devices and associated systems and methods

Info

Publication number: CA2782385A1
Application number: CA2782385A
Authority: CA
Inventors: Andrew H. Cragg; Stephen Sosnowski; Isa Rizk; John Fulkerson; John Logan
Original assignee: Altura Medical Inc
Current assignee: Altura Medical Inc
Priority date: 2009-12-01
Filing date: 2010-12-01
Publication date: 2011-06-09
Also published as: ES2581343T3; EP2559402B1; EP2559404A2; EP2506799A1; EP2506799A4; EP2559401A2; EP2559403B1; EP2559402A3; CN103260548A; EP2559402A2; JP2013059629A; JP2013512079A; JP2015192905A; JP2013034900A; EP2559403A2; US20110130819A1; ES2577853T3; EP2559401B1; JP2013034899A; US20110130824A1

Abstract

Modular endograft devices and associated systems and methods are disclosed herein. In several embodiments, an endograft system can include a first endograft device and a second endograft device that each include an integrated frame, a cover and a lumen within the cover. Each endograft device further includes a superior portion and an inferior portion. The superior portion can have a convexly curved outer wall and a septal wall. The first and second endograft devices can be configured to extend into a low-profile configuration with a first cross-sectional dimension and a first length and self-expand into an expanded configuration with a second cross-sectional dimension greater than the first cross-sectional dimension and a second length less than the first length. In the expanded configuration, the septal walls can press against each other and form a septum between the lumens of the first and second endograft devices.

Claims

1. A modular endograft system, comprising:
a first endograft device having an integrated first frame ("first frame"), a first cover attached to the first frame, and a first lumen within the first cover, wherein the first frame and the first cover have a first superior portion and a first inferior portion, and the first superior portion has a first outer wall and a first septal wall;
a second endograft device having an integrated second frame ("second frame"), a second cover attached to the second frame, and a second lumen within the second cover, wherein the second frame and the second cover have a second superior portion and a second inferior portion, the second superior portion having a second outer wall and a second septal wall; and wherein the first and second endograft devices are configured to be extended into a low-profile configuration with a first cross-sectional dimension and a first length and self-expand to an expanded configuration with a second cross-sectional dimension greater than the first cross-sectional area and a second length less than the first length such that in the expanded configuration the first and second septal walls press against each other and form a septum between the first and second lumens.

2. The modular endograft system of claim 1 wherein:
the first cover has a first superior terminus and the second cover has a second superior terminus;
the first frame includes a first end portion extending distally from the first superior terminus of the first cover, wherein the first end portion is configured to allow transverse fluid flow relative to a longitudinal axis of the first lumen; and the second frame includes a first end portion extending distally from the second superior terminus of the second cover, wherein the second end portion is configured to allow transverse fluid flow relative to a longitudinal axis of the second lumen.

3. The modular endograft system of claim 1 wherein:
the first cover has a first inferior terminus and the second cover has a second inferior terminus;
the first frame includes a second end portion extending proximally from the first inferior terminus of the first cover, wherein the second end portion is configured to allow transverse blood flow relative to a longitudinal axis of the first lumen; and the second frame includes a second end portion extending proximally from the second inferior terminus of the second cover, wherein the second end portion is configured to allow transverse fluid flow relative to a longitudinal axis of the second lumen.

4. The modular endograft system of claim 1 wherein:
the first and second frames each include a continuous wire woven in a braid, wherein the wire crosses itself at a braid angle.

5. The modular endograft system of claim 4 wherein:
the first frame includes a first superior terminus, a first inferior terminus, and wherein the wire reverses direction at the first superior terminus to form a first plurality of loops and reverses direction at the first inferior terminus to form a second plurality of loops; and the second frame includes a second superior terminus, a second inferior terminus, and wherein the wire reverses direction at the second superior terminus to form a first plurality of loops and reverses direction at the second inferior terminus to form a second plurality of loops.

6. The modular endograft system of claim 4 wherein the wire is unbound where it crosses itself.

7. The modular endograft system of claim 4 wherein:
the first superior portion has a cross-sectional dimension of at least 20 mm in the expanded configuration and a cross-sectional dimension of at most mm in the low-profile configuration; and the second superior portion has a cross-sectional dimension of at least 20 mm in the expanded configuration and a cross-sectional dimension of at most 5 mm in the low-profile configuration.

8. The modular endograft system of claim 4 wherein the braid angle is from approximately 30° to approximately 45°.

9. The modular endograft system of claim 5 wherein the wire has a diameter from approximately 0.0070 inch to approximately 0.0140 inch and the first plurality of loops includes no more than eight loops and the second plurality of loops includes no more than eight loops.

10. The modular endograft system of claim 4 wherein the first and second frames each include a superior terminus and an inferior terminus, the wire is one of a plurality of wires, and wherein individual wires terminate at staggered points between the superior and inferior termini of the first and second frames.

11. The modular endograft system of claim 10 wherein the superior portion of the frame has a greater number of wires in the braid than the inferior portion of the frame.

12. The modular endograft system of claim 1 wherein:
the first cover has a first superior terminus and a first inferior terminus and the second cover has a second superior terminus and a second inferior terminus;

the first cover is attached over the first frame at the first superior terminus and the first inferior terminus of the first cover, wherein the first cover and the first frame are configured such that the first cover substantially conforms to the first frame in the expanded configuration; and the second cover is attached over the second frame at the second superior terminus and the second inferior terminus of the second cover, wherein the second cover and the second frame are configured such that the second cover substantially conforms to the second frame in the expanded configuration.

13. The modular endograft system of claim 1 wherein:
the first cover includes a plurality of first ribs, the first ribs protruding radially from the first frame in the expanded configuration and being extendable longitudinally in the low-profile configuration;
the second cover includes a plurality of second ribs, the second ribs protruding radially from the second frame in the expanded configuration and being extendable longitudinally in the low-profile configuration; and wherein the first ribs on the first septal wall mate with the second ribs at the second septal wall in the expanded configuration.

14. The modular endograft system of claim 1 wherein:
the first cover limits radial expansion of the first frame in the expanded configuration; and the second cover limits radial expansion of the second frame in the expanded configuration.

15. The modular endograft system of 1 wherein:
the first cover includes a first superior terminus and a first inferior terminus, and at least one of the first superior terminus and the first inferior terminus is zigzagged; and the second cover includes a second superior terminus and a second inferior terminus, and at least one of the second superior terminus and the second inferior terminus is zigzagged.

16. The modular endograft system of claim 1 wherein:
the first and second superior portions of the first and second endografts, respectively, include alignment aids on opposing first and second septal walls, the alignment aids being configured to cross one another when the first and second septal walls form the septum.

17. The modular endograft system of claim 16 wherein each of the alignment aids diagonally cross the first and second septal walls, and wherein the first and second alignment aids form an "X" indicator when the first and second septal walls at the septum.

18. The modular endograft system of claim 16, wherein:
the first cover has a first superior terminus and the second cover has a second superior terminus;
the first alignment aid terminates at the first superior terminus of the first cover; and the second alignment aid terminates at the second superior terminus of the second cover.

19. The modular endograft system of claim 1 wherein:
the first endograft device includes at least one anchor projecting radially from the first outer wall of the first frame in the expanded configuration; and the second endograft device includes at least one anchor projecting radially from the second outer wall of the second frame in the expanded configuration.

20. The modular endograft system of claim 19 wherein the first and second anchors are retracted in the low-profile configuration and project inferiorly from the first and second outer walls in the expanded configuration.

21. The modular endograft system of claim 1 wherein the first cover includes an opening at the first outer wall through which blood can flow laterally across the first lumen.

22. The modular endograft system of claim 1 wherein:
the first and second lumens have a first cross-sectional dimension at the first and second superior portions and a second cross-sectional dimension less than the first cross-sectional dimension at the first and second inferior portions;
the first endograft device further includes a first transition portion between the first superior portion and the first inferior portion, the first transition portion tapering the first lumen from the first cross-sectional dimension to the second cross-sectional dimension and being configured to maintain substantially laminar blood flow through the first lumen in the expanded configuration; and the second endograft device further includes a second transition portion between the second superior portion and the second inferior portion, the second transition portion tapering the second lumen from the first cross-sectional dimension to the second cross-sectional dimension and being configured to maintain substantially laminar blood flow through the second lumen in the expanded configuration.

23. The modular endograft system of claim 1 wherein the first and second outer and septal walls are convexly curved, and wherein:
the first outer wall and the first septal wall define a first complex ellipsoid, the first outer wall having a first radius, and the first septal wall having a second radius greater than the first radius;
the second outer wall and the second septal wall define a second complex ellipsoid, the second outer wall having the first radius, and the second septal wall having the second radius greater than the first radius; and the first and second complex ellipsoids have a substantially D-like shape and relative forces between first and second septal walls in the expanded configuration are substantially uniform along the septum.

24. A modular endograft system, comprising:
a first endograft device having a first frame, a first cover, and a first lumen within the first cover, wherein the first frame and the first cover have a first superior portion and a first inferior portion, and the first superior portion has a convexly curved first outer wall and a first septal wall;
a second endograft device having a second frame, a second cover, and a second lumen within the second cover, wherein the second frame and the second cover have a second superior portion and a second inferior portion, the second superior portion having a convexly curved second outer wall and a second septal wall;
wherein the first and second frames are configured to have substantially continuous longitudinal support along the superior and inferior portions of the first and second endograft devices, respectively; and wherein the first and second septa[ walls press against each other and form a septum in an expanded configuration between the first and second lumens.

25. The modular endograft system of claim 24 wherein the first and second frames are braided frames woven from a wire such that each longitudinal segment of each frame supports adjacent longitudinal segments along the length of each frame.

26. The modular endograft system of claim 25 wherein each longitudinal segment of the frame influences the radial expansion or contraction of the adjacent longitudinal segment of the frame.

27. The modular endograft system of claim 25 wherein the first and second frames each include a superior terminus and an inferior terminus, and a wire crossing itself at a braid angle, and wherein the wire reverses direction at the superior terminus to form a first plurality of loops and reverses direction at the inferior terminus to form a second plurality of loops the wire.

28. The modular endograft system of claim 27 wherein the wire crosses itself at a braid angle between approximaly 30° and approximately 45°.

29. The modular endograft system of 28 wherein:
the first and second covers each include a superior terminus and an inferior terminus, and at least one of the superior and inferior termini of the cover conforms to the braid angle.

30. The modular endograft system of claim 24 wherein:
the first and second superior portions have a cross-sectional dimension of at least 20 mm in the expanded configuration and a cross-sectional dimension of at most 5 mm in the low-profile configuration.

31. The modular endograft system of claim 24 wherein the first endograft device has a first alignment aid and the second endograft device has a second alignment aid, wherein the first and second alignment aids are configured to indicate a rotational orientation and a longitudinal position of the first and second endograft devices relative to each other.

32. The modular endograft system of claim 24 wherein the first and second endograft devices each include at least one anchor at the superior portion, wherein the anchor protrudes radially from the outer wall in an expanded configuration and constricts in a low-profile configuration.

33. The modular endograft system of claim 24 wherein at least a portion of the first and second covers have a plurality of circumferential ribs projecting radially from the first and second frames, respectively, and wherein the circumferential ribs at the first septal wall of the first endograft device are configured to mate with the circumferential ribs at the second septal wall of the second endograft device at the septum.

34. The modular endograft system of claim 24 wherein the first cover includes an opening at the first outer wall, wherein the blood can flow laterally through the opening across the first lumen.

35. The modular endograft system of claim 24 wherein the first and second septal walls are convexly curved, and wherein:
the first and second outer walls and the first and second septa[ walls define first and second complex ellipsoids, respectively, the first and second outer walls having a first radius, and the first and second septal walls having a second radius greater than the first radius;
the first and second complex ellipsoids have a substantially D-like shape and relative forces between first and second septal walls in the expanded configuration are substantially uniform along the septum;
the first and second lumens have a first cross-sectional dimension at the first and second superior portions and a second cross-sectional dimension less than the first cross-sectional dimension at the first and second inferior portions; and the first and second endograft devices each include a transition portion between the superior portion and the inferior portion, the transition portion tapering the lumen from the first cross-sectional dimension to the second cross-sectional dimension and being configured to maintain substantially laminar blood flow through the lumen in the expanded configuration.

36. A method of repairing an aneurysm in a primary blood vessel before the primary blood vessel bifurcates into a first blood vessel and a second blood vessel, the method comprising:
advancing a first endograft device through the first blood vessel to a target site in the primary blood vessel to a target site before the aneurysm, wherein the first endograft device includes a first frame, a first cover, and a first lumen within the first cover, wherein the first frame and the first cover have a first superior portion and a first inferior portion, the first superior portion having a first outer wall and a first septal wall;
advancing a second endograft device through the second blood vessel to the target site, wherein the second endograft device includes a second frame, a second cover, and a second lumen within the second cover, wherein the second frame and the second cover have a second superior portion and a second inferior portion, and the second superior portion having a second outer wall and a second septal wall;
deploying the first and second endograft devices at the target site such that the first and second endograft devices self-expand to an expanded configuration via inherent hoop forces in the first and second frames such that the first and second septal walls press against each other to form a septum between the first and second lumens, the first and second outer walls press against a vessel wall of the primary blood vessel; and wherein the first and second endograft devices are positioned independently of one another.

37. The method of claim 36 wherein positioning the first and second endograft devices independently comprises:
positioning the first superior portion of the first endograft device in a first desired position; and positioning the second superior portion of the second endograft device in a second desired position, wherein the first desired position is longitudinally offset from the second desired position along the primary vessel.

38. The method of claim 36, further comprising:
loading the first endograft device in a first catheter, wherein the first endograft device is extended in a low-profile configuration;
loading the second endograft device in a second catheter, wherein the second endograft device is extended in a low-profile configuration;
percutaneously introducing the first endograft device into the first blood vessel; and percutaneously introducing the second endograft device into the second blood vessel.

39. The method of claim 36 wherein the first and second endograft devices have a cross-sectional dimension no less than 20 mm in the expanded configuration, and wherein the first and second catheters are no larger than 12 F.

40. The method of claim 36 wherein the first endograft device includes a first alignment aid at the first septal wall, wherein the second endograft device includes a second alignment aid at the second septal wall, the first and second alignment aids comprising a radiopaque material, and wherein deploying the first and second endograft devices further includes:
radiographically positioning the first and second alignment aids such that the first and second alignment aids are opposite another;
viewing the first and second alignment aids in the orthogonal plane; and crossing the first and second alignment aids such that the first and second septal walls can form the septum.

41. The method of claim 40 wherein the first and second alignment aids diagonally cross the first and second septal walls, respectively, and wherein crossing the first and second alignment aids forms an "X" indicator.

42. The method of claim 36 wherein the first cover includes first ribs on the first septal wall and the second cover includes second ribs at the second septal wall, and wherein deploying the first and second endograft devices further comprise mating the first and second ribs.

43. The method of claim 36 wherein the first cover attaches over at least a portion of the first frame, the second cover attaches over at least a portion of the second frame, and deploying the first and second endograft devices further comprises:
restricting radial expansion of the first frame with the first cover; and restricting radial expansion of the second frame with the second cover.

44. The method of claim 36 wherein the first cover includes an opening at the first outer wall of the first superior portion, and wherein deploying the first and second endograft devices further comprises:
positioning the opening at an entrance of a third blood vessel, the third blood vessel having transverse fluid flow relative to a longitudinal axis of the primary blood vessel, and wherein the opening allows blood to flow through the first lumen and to the third blood vessel.

45. A modular endograft system, comprising:
a first endograft device having a first superior portion, a first inferior portion having a smaller cross-sectional dimension than the first superior portion, and a first lumen through the first superior and first inferior portions, the first superior portion having a convexly curved first outer wall and a first septal wall that define a substantially D-shaped cross-section;
a second endograft device having a second superior portion, a second inferior portion having a smaller cross-sectional dimension than the second superior portion, and a second lumen through the second superior and second inferior portions, the second superior portion having a convexly curved second outer wall and a second septal wall that define a substantially D-shaped cross-section; and wherein the first and second endograft devices are configured to self-expand into an expanded configuration via inherent hoop force of the first and second endograft devices such that the first and second septal walls press against each other and form a septum between the first and second lumens.

46. The modular endograft system of claim 45 wherein the first and second septal walls are convexly curved, and wherein:
the first outer wall and the first septal wall define a first complex ellipsoid in which the first outer wall has a first radius and the first septal wall has a second radius greater than the first radius;

the second outer wall and the second septal wall define a second complex ellipsoid in which the second outer wall has the first radius and the second septal wall has the second radius; and the self-expansion of the first and second endograft devices produces opposing forces between first and second septal walls in the expanded configuration.

47. The modular endograft system of claim 46 wherein the opposing forces between the first and second septal walls are substantially uniform along the septum.

48. The modular endograft system of claim 45 wherein the first and second septal walls are at least substantially straight.

49. The modular endograft system of claim 45 wherein the inferior portions have a substantially circular cross-section.

50. The modular endograft system of claim 45 wherein:
the first endograft device has a first frame and a first cover attached to the first frame, the first cover having a plurality of first circumferential ribs; and the second endograft device has a second frame and a second cover attached to the second frame, the second cover having a plurality of second circumferential ribs mated with the first circumferential ribs along at least a portion of the first and second septal walls.

51. The modular endograft system of claim 45 wherein:
the first septal wall is convexly curved in an opposite direction relative to the first outer wall, and the first septal wall and the first outer wall are joined at curved corners; and the second septal wall is convexly curved in an opposite direction relative to the second outer wall, and the second septal wall and the second outer wall are joined at curved corners.

52. The modular endograft system of claim 51 wherein:
the first outer wall and the second outer wall each have a first radius of curvature;
the first septal wall and the second septal wall each have a second radius of curvature greater than the first radius of curvature; and the curved corners have a radius of curvature less than the first radius of curvature.

53. The modular endograft system of claim 45 wherein the first endograft device has a first alignment marker and the second endograft device has a second alignment marker, wherein the first and second alignment markers are configured to indicate at least one of a rotational orientation and longitudinal position of the first and second endograft devices relative to each other.

54. The modular endograft device of claim 45 wherein:
the first endograft device has a first braided frame and a first cover attached to the first braided frame, the first cover having a first inferior terminus and a first superior terminus, and the first braided frame having a first end extending distally beyond the first superior terminus of the first cover and second end extending proximally beyond the first inferior terminus of the first cover; and the second endograft device has a second braided frame and a second cover attached to the second braided frame, the second cover having a second inferior terminus and a second superior terminus, and the second braided frame having a first end extending distally beyond the second superior terminus of the second cover and a second end extending proximally beyond the second inferior terminus of the second cover.

55. The modular endograft system of claim 45 wherein:
the first endograft device has a first frame and a first cover attached to the first frame, the first frame comprising an open braided wire, and the first cover having a first opening at the first outer wall;

the second endograft device has a second frame and a second cover attached to the second frame, the second frame comprising an open braided wire, and the second cover having a second opening at the second outer wall; and wherein the first and second openings allow blood to flow laterally relative to a longitudinal axis of the first and second lumens.

56. A modular endograft system, comprising:
a first endograft device having a first superior portion with a first distal section, a first inferior portion, and a first lumen through the first superior and first inferior portions, the first superior portion having a convexly curved first outer wall and a first septal wall that define a substantially D-shaped cross-section;
a second endograft device having a second superior portion with a second distal section, a second inferior portion, and a second lumen through the second superior and second inferior portions, the second superior portion having a convexly curved second outer wall and a second septal wall that define a substantially D-shaped cross-section; and wherein the first and second endograft devices are longitudinally staggered with respect to each other such that the first distal section of the first endograft device is positioned superiorly relative to the second distal section of the second endograft device.

57. The modular endograft system of claim 56 wherein:
the first endograft device has a first frame and a first cover attached to the first frame, the first cover having a first inferior terminus and a first superior terminus, and the first frame having a first end extending distally beyond the first superior terminus of the first cover, wherein the first end of the first frame defines the first distal section of the first endograft device; and the second endograft device has a second frame and a second cover attached to the second frame, the second cover having a second inferior terminus and a second superior terminus, and the second frame having a first end extending distally beyond the second superior terminus of the second cover, wherein the first end of the second frame defines the second distal section of the second endograft device.

58. The modular endograft system of claim 57 wherein the first ends of the first and second frames have openings through which blood can flow laterally relative to a longitudinal axis of the first and second lumens.

59. The modular endograft device of claim 56 wherein the first and second septal walls are convexly curved, and wherein:
the first outer wall and the first septal wall define a first complex ellipsoid in which the first outer wall has a first radius and the first septal wall has a second radius greater than the first radius;
the second outer wall and the second septal wall define a second complex ellipsoid in which the second outer wall has the first radius and the second septal wall has the second radius; and the self-expansion of the first and second endograft devices produces opposing forces between first and second septal walls in an expanded configuration.

60. The modular endograft system of claim 59 wherein the pressure between the first and second septal walls is substantially uniform along the septum.

61. The modular endograft system of claim 56 wherein the first and second septal walls are at least substantially straight.

62. The modular endograft system of claim 56 wherein:
the first septal wall is convexly curved in an opposite direction relative to the first outer wall, and the first septal wall and the first outer wall are joined at curved corners; and the second septal wall is convexly curved in an opposite direction relative to the second outer wall, and the second septal wall and the second outer wall are joined at curved corners.

63. The modular endograft system of claim 62 wherein:
the first outer wall and the second outer wall each have a first radius of curvature;
the first septal wall and the second septal wall each have a second radius of curvature greater than the first radius of curvature; and the curved corners have a radius of curvature less then the first radius of curvature.

64. The modular endograft system of claim 56 wherein:
the first superior portion has a cross-sectional dimension of at least 20 mm in an expanded configuration and a cross-sectional dimension of at most mm in a low-profile configuration; and the second superior portion has a cross-sectional dimension of at least 20 mm in an expanded configuration and a cross-sectional dimension of at most 5 mm in a low-profile configuration.

65. A modular endograft system comprising:
a first endograft device having a first superior portion, a first inferior portion having a smaller cross-sectional dimension than the first superior portion, a first braided frame, and a first lumen through the first superior and first inferior portions, the first superior portion having a substantially D-shaped cross-section;
a second endograft device having a second superior portion, a second inferior portion having a smaller cross-sectional dimension than the second superior portion, a second braided frame, and a second lumen through the second superior and second inferior portions, the second superior portion having a substantially D-shaped cross-section;
wherein the first and second braided frames are configured to have substantially continuous longitudinal support along the superior and inferior portions of the first and second endograft devices, respectively;
and wherein the first and second superior portions press against each other and form a septum between the first and second lumens.

66. The modular endograft system of claim 65 wherein the first and second braided frames are woven from a wire such that each longitudinal segment of each frame supports adjacent longitudinal segments along the length of each frame.

67. The modular endograft system of claim 66 wherein each longitudinal segment of the frame influences the radial expansion or contraction of the adjacent longitudinal segment of the frame.

68. The modular endograft system of claim 65 wherein the first and second septal walls are convexly curved, and wherein:
the first superior portion includes a convexly curved first outer wall and a convexly curved first septal wall, wherein the first outer wall has a first radius and the first septal wall has a second radius greater than the first radius;
the second superior portion includes a convexly curved second outer wall and a convexly curved second septal wall, wherein the second outer wall has the first radius and the second septal wall has the second radius;
and the first and second endograft devices are configured to self-expand via an inherent spring force such that the first and second septal walls exert opposing forces against each other.

69. The modular endograft system of claim 65 wherein the first endograft device has a first alignment aid and the second endograft device has a second alignment aid, and wherein the first and second alignment aids are configured to indicate a rotational orientation and a longitudinal position of the first and second endograft devices relative to each other.

70. The modular endograft system of claim 65 wherein:
the first endograft device further includes a first tapered transition portion between the first superior portion and the first inferior portion, wherein the transition portion is configured to maintain substantially laminar blood flow through the first lumen in an expanded configuration; and the second endograft device further includes a second tapered transition portion between the second superior portion and the second inferior portion, wherein the second transition portion is configured to maintain substantially laminar blood flow through the second lumen in an expanded configuration.

71. The modular endograft system of claim 65 wherein the first endograft device has a first cover attached to a portion of the first frame, and the first cover having a first opening, and wherein the first opening allows blood to flow laterally relative to the first lumen.

72. The modular endograft system of claim 65 wherein:
the first superior portion has a cross-sectional dimension of at least 20 mm in an expanded configuration and a cross-sectional dimension of at most mm in a low-profile configuration; and the second superior portion has a cross-sectional dimension of at least 20 mm in an expanded configuration and a cross-sectional dimension of at most 5 mm in a low-profile configuration.

73. A method of treating an aneurysm located in a primary vessel before a bifurcation into a first vessel and a second vessel, comprising:
positioning a first endograft device relative to the aneurysm such that at least a segment of a first superior portion of the first endograft device is positioned superior to the aneurysm and a first inferior portion of the first endograft device extends at least partially through the aneurysm, the first superior portion having a convexly curved first outer wall and a first septal wall that define a substantially D-shaped cross-section;
positioning a second endograft device relative to an aneurysm such that at least a segment of a second superior portion of the second endograft device is positioned superior to the aneurysm and a second inferior portion of the second endograft device extends at least partially through the aneurysm, the second superior portion having a convexly curved second outer wall and a second septal wall that define a substantially D-shaped cross-section, and wherein the second endograft device is positioned independently of positioning the first endograft device;
deploying the first endograft device from a first catheter and deploying the second endograft device from a second catheter such that the first and second superior portions self-expand to an expanded configuration in which the first and second septal walls press against each other via an inherent spring force to form a septum between the first and second lumens.

74. The method of claim 73 wherein the first septal wall is convexly curved in a direction opposite the first outer wall and the second septal wall is convexly curved in a direction opposite the second outer wall, and wherein deploying the first and second endograft devices comprises urging the convexly curved first and second septal walls together.

75. The method of claim 74 wherein urging convexly the curved first and second septal walls together results in a more uniform distribution of pressure between the first and second septal walls compared to straight first and second septal walls.

76. The method of claim 73 wherein positioning the first and second endograft devices independently of each other comprises staggering the first superior portion of the first endograft device relative to the second superior portion of the second endograft device such that a portion of the first septal wall is positioned superior relative to a distal terminus of the second septal wall.

77. The method of claim 73 wherein:
the first catheter has a maximum cross-sectional dimension of 5mm and the first outer wall of the first superior portion of the first endograft device has a radius of curvature not less than 10mm after being deployed from the first catheter; and the second catheter has a maximum cross-sectional dimension of 5mm and the second outer wall of the second superior portion of the second endograft device has a radius of curvature not less than 10mm after being deployed from the second catheter.

78. The method of claim 73 wherein:
the first catheter has a maximum cross-sectional dimension of 5mm and the first outer wall of the first superior portion of the first endograft device has a radius of curvature not less than 10mm after being deployed from the first catheter; and the second catheter has a maximum cross-sectional dimension of 5mm and the second outer wall of the second superior portion of the second endograft device has a radius of curvature not less than 10mm after being deployed from the second catheter.

79. The method of claim 73 wherein the primary blood vessel includes a third blood vessel and a fourth blood vessel branching from the primary blood vessel before the aneurysm, the third and fourth blood vessels being longitudinally offset along the primary blood vessel, and wherein:
the first endograft device has a first frame and a first cover attached to a portion of the first frame, the first frame comprising an open braided wire, and the first cover having a first opening at the first outer wall;
the second endograft device has a second frame and a second cover attached to the second frame, the second frame comprising an open braided wire, and the second cover having a second opening at the second outer wall, wherein the first and second openings allow blood to flow laterally relative to a longitudinal axis of the first lumen and second lumen; and deploying the first and second endograft devices comprises positioning the first end portion of the first frame at the entrance of the third blood vessel and positioning the first end portion of the second frame at the entrance of the fourth blood vessel such that the first and second endograft devices are staggered with respect to a longitudinal axis of the primary vessel.

80. A modular endograft system, comprising:
a first guidewire;
a first endograft device positioned along the first guidewire, the first endograft device having a first superior portion, a first inferior portion, and a first lumen through the first superior and inferior portions, and the first superior portion having a first outer wall and a first septal wall;
a first limb positioned along the first guidewire and coupled to the first inferior portion of the first endograft device;
a second guidewire;
a second endograft device positioned along the second guidewire, the second endograft device having a second superior portion, a second inferior portion, and a second lumen through the second superior and inferior portions, and the second superior portion having a second outer wall and a second septal wall, wherein the first septal wall of the first endograft device presses against the second septal wall of the second endograft device; and a second limb positioned along the second guidewire and coupled to the second inferior portion of the second endograft device.

81. The modular endograft system of claim 80, wherein:
the first outer wall is convexly curved, and the first septal wall and first outer wall form a substantially D-shaped cross-section; and the second outer wall is convexly curved, and the second septal wall and the second outer wall form a substantially D-shaped cross-section.

82. The modular endograft system of claim 81, wherein:
the first septal wall is convexly curved in a direction opposite the convex curvature of the first outer wall; and the second septal wall is convexly curved in a direction opposite the convex curvature of the second outer wall.

83. The modular endograft system of claim 81, wherein the first and second septal walls are at least substantially straight and form a septum.

84. The modular endograft system of claim 80 wherein:
the first and second inferior portions of the first and second endograft devices have a circular cross-section; and the first and second limbs have circular cross-sections.

85. The modular endograft system of claim 80 wherein:
the first endograft device has an integrated first frame ("first frame") and a first cover exterior of the first frame, wherein the first lumen is within the first cover, and wherein the first cover has a first superior terminus and the first frame has a first end portion extending distally from the first superior terminus of the first cover; and the second endograft device has an integrated second frame ("second frame") and a second cover exterior of the second frame, wherein the second lumen is within the second cover, and wherein the second cover has a second superior terminus and the second frame has a first end extending distally from the second superior terminus of the second cover.

86. The modular endograft device of claim 85, wherein the first and second frames each include a superior terminus, an inferior terminus, and a continuous wire woven in a braid in which the wire crosses itself at a braid angle, and wherein the wire reverses direction at the superior terminus of the frame to form a first plurality of loops and reversing direction at the inferior terminus of the frame to form a second plurality of loops.

87. The modular endograft system of claim 86 wherein the wire is unbound where it crosses itself.

88. The modular endograft device of claim 86 wherein the braid angle is from approximately 30° to approximately 45°.

89. The modular endograft device of claim 86, wherein:
the first cover includes a plurality of first ribs, the first ribs protruding radially from the first frame in an expanded configuration and being extendable longitudinally in a low-profile configuration;
the second cover includes a plurality of second ribs, the second ribs protruding radially from the second frame in an expanded configuration and being extendable longitudinally in a low-profile configuration; and wherein the first ribs on the first septal wall interface with the second ribs at the second septal wall in the expanded configuration.

90. The modular endograft device of claim 81 wherein:
the first superior portion has a cross-sectional dimension of at least 20 mm in an expanded configuration and a cross-sectional dimension of at most mm in a low-profile configuration; and the second superior portion has a cross-sectional dimension of at least 20 mm in an expanded configuration and a cross-sectional dimension of at most 5 mm in a low-profile configuration.

91. The modular endograft system of claim 81 wherein:
the first endograft device includes a plurality of first ribs;
the second endograft device includes a plurality of second ribs; and the first ribs mate with the second ribs in an expanded configuration.

92. The modular endograft system of claim 81 wherein the first and second limbs each include a cover having a plurality of circumferential ribs protruding radially from the cover, the ribs of the first limb contacting an interior of the first inferior portion, and the ribs of the second limb contact an interior of the second inferior portion.

93. The modular endograft system of claim 81, further comprising:
a first alignment aid at the first septal wall;
a second alignment aid at the second septal wall, wherein the second alignment aid crosses the first alignment aid when the first and second septal walls are aligned; and wherein the first and second alignment aids comprise a radiopaque material.

94. A modular endograft system comprising:
a first guidewire;
a first endograft device positioned along the first guidewire, the first endograft device having a first superior portion, a first inferior portion, a first braided frame, and a first lumen through the first superior and inferior portions;
a first limb positioned along the first guidewire and coupled to the first inferior portion of the first endograft device;
a second guidewire;
a second endograft device positioned along the second guidewire, the second endograft device having a second superior portion, a second inferior portion, a second braided frame, and a second lumen through the second superior and inferior portions, wherein septal walls of the first and second endograft devices press against one another to form a septum; and a second limb positioned along the second guidewire and coupled to the second inferior portion of the second endograft device; and wherein the first and second braided frames are configured to have substantially continuous longitudinal support along the superior and inferior portions of the first and second endograft devices, respectively.

95. The modular endograft system of claim 94 wherein the first and second braided frames are woven from a wire such that each longitudinal segment of each frame supports adjacent longitudinal segments along the length of each frame.

96. The modular endograft system of claim 95 wherein each longitudinal segment of the frame influences the radial expansion or contraction of the adjacent longitudinal segment of the frame.

97. The modular endograft system of claim 94 wherein:
the first and second superior portions each include a convexly curved outer wall and a convexly curved septal wall, the outer walls having a first radius of curvature and the septal walls having a second radius of curvature less than the first radius of curvature such that the first and second superior portions have a substantially D-like cross-sectional shape; and the first and second endograft devices expand via an inherent spring force such that opposing forces between the first and second septal walls are substantially uniform along the septum.

98. The modular endograft system of claim 94 wherein the first endograft device has a first alignment aid and the second endograft device has a second alignment aid, and wherein the first and second alignment aids are configured to indicate a rotational orientation and a longitudinal position of the first and second endograft devices relative to each other.

99. The modular endograft system of claim 94 wherein the first endograft device has a first cover attached to a portion of the first frame, and the first cover having a first opening, and wherein the first opening allows blood to flow laterally relative to the first lumen.

100. The modular endograft system of claim 94 wherein:
the first superior portion has a cross-sectional dimension of at least 20 mm in an expanded configuration and a cross-sectional dimension of at most mm in a low-profile configuration; and the second superior portion has a cross-sectional dimension of at least 20 mm in an expanded configuration and a cross-sectional dimension of at most 5 mm in a low-profile configuration.

101. The modular endograft system of claim 94 wherein:
the first and second endograft devices include first and second covers, respectively, the first and second covers having a plurality of circumferential ribs that protrude radially;
the first limb includes a third cover having a plurality of circumferential ribs that protrude radially;
the second limb includes a fourth cover having a plurality of circumferential ribs that protrude radially;
the third cover of the first limb contacts an interior of the first inferior portion of the first endograft device such that the ribs on the third cover interface with the ribs on the first cover of the first endograft device; and the fourth cover of the second limb contacts an interior of the second inferior portion of the second endograft device such that the ribs on the fourth cover interface with the ribs on the second cover of the second endograft device.

102. The modular endograft device of claim 94 wherein:
the first endograft device includes a first transition portion between the first superior portion and the first inferior portion, the first transition portion tapering the first lumen from a first cross-sectional dimension at the superior portion to a second cross-sectional dimension less than the first cross-sectional dimension at the inferior portion, wherein the transition portion is configured to maintain substantially laminar blood flow through the first lumen in the expanded configuration; and the second endograft device includes a second transition portion between the second superior portion and the second inferior portion, the second transition portion tapering the second lumen from the first cross-sectional dimension at the second superior portion to the second cross-sectional dimension at the second inferior portion, wherein the second transition portion is configured to maintain substantially laminar blood flow through the second lumen in the expanded configuration.

103. A method of treating an aneurysm in a primary vessel at a location before a bifurcation into a first vessel and a second vessel, the method comprising:
positioning a first endograft device over a first guidewire relative to the aneurysm such that at least a segment of a first superior portion of the first endograft device is positioned superior to the aneurysm and a first inferior portion of the first endograft device extends only partially through the aneurysm, the first superior portion having a convexly curved first outer wall and a first septal wall;
positioning a second endograft device over a second guidewire relative to the aneurysm such that at least a segment of a second superior portion of the second endograft device is positioned superior to the aneurysm and a second inferior portion of the second endograft device extends only partially through the aneurysm, the second superior portion having a convexly curved second outer wall and a second septal wall, and wherein the second endograft device is positioned independently of positioning the first endograft device;
deploying the first endograft device from a first catheter and deploying the second endograft device from a second catheter such that the first and second septal walls press against each other to form a septum between the first and second endograft devices;
implanting a first limb over the first guidewire such that a distal portion of the first limb is coupled to the first inferior portion of the first endograft device and a proximal portion of the first limb is in the first vessel; and implanting a second limb over the second guidewire such that a distal portion of the second limb is coupled to the second inferior portion of the second endograft device and a proximal portion of the second limb is in the second vessel.

104. The method of claim 103, wherein the first septal wall is convexly curved in a direction opposite the first outer wall and the second septal wall is convexly curved in a direction opposite the second outer wall, and wherein deploying the first and second endograft devices comprises urging the convexly curved first and second septal walls together.

105. The method of claim 104 wherein urging the convexly curved first and second septal walls together results in a more uniform distribution of pressure between the first and second septal walls compared to straight first and second septal walls.

106. The method of claim 103 wherein positioning the first and second endograft devices comprises staggering the first superior portion of the first endograft device relative to the second superior portion of the second endograft device such that a portion of the first septal wall is positioned superior relative to a distal most terminus of the second septal wall.

107. The method of claim 103 wherein:
the first catheter has a maximum cross-sectional dimension of 5 mm and the first outer wall of the first superior portion of the first endograft device has a radius of curvature not less than 10 mm after being deployed from the first catheter; and the second catheter has a maximum cross-sectional dimension of 5 mm and the second outer wall of the second superior portion of the second endograft device has a radius of curvature not less than 10 mm after being deployed from the second catheter.

108. The method of claim 103 wherein the first endograft device includes a first alignment aid at the first septal wall, wherein the second endograft device includes a second alignment aid at the second septal wall, the first and second alignment aids comprising a radiopaque material, and wherein deploying the first and second endograft devices further includes:
radiographically positioning the first and second alignment aids such that the first and second alignment aids oppose one another;
viewing the first and second alignment aids in the orthogonal plane; and crossing the first and second alignment aids such that the first and second septal walls form the septum.

109. The method of claim 103 wherein the primary blood vessel includes a third blood vessel branching from the primary blood vessel before the aneurysm, and wherein:
the first endograft device includes a frame, a cover, and a lumen within the cover, wherein a superior end portion of the frame projects distally beyond a superior terminus of the cover; and deploying the first and second endograft devices includes positioning the distal end portion of the first endograft device at the third blood vessel such that blood flows laterally through the distal end portion relative to a longitudinal axis of the lumen.

110. The method of claim 103 wherein implanting the first and second limbs further comprises:
positioning the distal portion of the first limb within the first inferior portion and expanding the first limb via an inherent spring force in the second limb to contact an internal surface of the first inferior portion; and positioning the distal portion of the second limb within the second inferior portion and expanding the second limb via an inherent spring force in the second limb to contact an internal surface of the second inferior portion.

111. The method of claim 110 wherein positioning the distal portions of the first and second limbs further comprises:
adjusting the length of the first limb within the first inferior portion such that the proximal portion of the second limb presses against an interior the second vessel; and adjusting a length of the second limb within the second inferior portion such that the proximal portion of the second limb presses against an interior the second vessel.

112. A modular endograft system, comprising:
a first endograft device having a first superior portion, a first inferior portion, and a first lumen through the first superior and inferior portions, wherein the first superior portion has a first superior terminus, a first outer wall, and a first septal wall;
a second endograft device having a second superior portion, a second inferior portion, and a second lumen through the second superior and inferior portions, wherein the second superior portion has a second superior terminus, a second outer wall, and a second septal wall;
wherein the first and second septal walls of the first and second endograft devices press against one another and form a septum; and wherein the first superior terminus of the first endograft device is superior to the second superior terminus of the second endograft device such that the first and second endograft devices are longitudinally staggered and a free end portion of the first superior portion is positioned distally beyond the second superior terminus.

113. The modular endograft system of claim 112 wherein the first and second septal walls are convexly curved, and wherein:
the first outer wall and the first septal wall define a first complex ellipsoid, wherein the first outer wall has a first radius and the first septal wall has a second radius greater than the first radius;
the second outer wall and the second septal wall define a second complex ellipsoid, wherein the second outer wall has the first radius and the second septal wall has the second radius;
the first and second complex ellipsoids have a substantially D-shaped cross section; and the first and second endograft devices are configured to self-expand via an inherent spring force such that the first and second septal walls exert opposing forces against each other.

114. The modular endograft system of claim 113 wherein the opposing forces between the first and second septal walls are substantially uniform along the septum.

115. The modular endograft system of claim 112 wherein the first and second septal walls are at least substantially straight along the septum and the free end portion of the first superior portion is at least substantially longitudinally aligned with the first septal wall at the septum.

116. The modular endograft system of claim 115 wherein the first endograft device has an integrated, self-expanding frame configured to have integrated, continuous support longitudinally along the frame such that each area of the frame influences the radial expansion or contraction of an adjacent area of the frame.

117. The modular endograft system of claim 112 wherein the first and second inferior portions have a substantially circular cross-section.

118. The modular endograft system of claim 112 wherein:
the first endograft device has a first frame and a first cover attached to the first frame, the first cover having a plurality of first circumferential ribs;
the second endograft device has a second frame and a second cover attached to the second frame, the second cover having a plurality of second circumferential ribs; and wherein the first and second circumferential ribs interface at the septum.

119. The modular endograft system of claim 112 wherein:
the first septal wall is convexly curved in an opposite direction relative to the first outer wall, and the first septal wall and the first outer wall are joined at curved corners; and the second septal wall is convexly curved in an opposite direction relative to the second outer wall, and the second septal wall and the second outer wall are joined at curved corners.

120. The modular endograft system of claim 119 wherein:
the first outer wall and the second outer wall each have a first radius of curvature;

the first septal wall and the second septal wall each have a second radius of curvature greater than the first radius of curvature; and the curved corners have a radius of curvature less than the first radius of curvature, and wherein the curved corners form an angle from approximately 60° to approximately 100° at the septum in an expanded configuration.

121. The modular endograft system of claim 112 wherein the first endograft device has a first alignment aid and the second endograft device has a second alignment aid, wherein the first and second alignment aids are configured to indicate a rotational orientation and a longitudinal position of the first and second endograft devices relative to each other.

122. The modular endograft system of claim 112 wherein:
the first endograft device has a first braided frame configured to have a spring force that self-expands radially outward from a constricted profile to an expanded profile and a first cover attached to the first braided frame, the first cover having a first inferior terminus and a first superior terminus, and the first braided frame having a first end extending distally beyond the first superior terminus of the first cover and second end extending proximally beyond the first inferior terminus of the first cover;
the second endograft device has a second braided frame configured to have a spring force that self-expands radially outward from a constricted profile to an expanded profile and a second cover attached to the second braided frame, the second cover having a second inferior terminus and a second superior terminus, and the second braided frame having a first end extending distally beyond the second superior terminus of the second cover and a second end extending proximally beyond the second inferior terminus of the second cover; and wherein the first ends of the first and second frames include openings through which blood can flow laterally relative to the first and the second lumens.

123. The modular endograft system of claim 122, wherein the first and second braided frames are woven from wire such that each longitudinal segment of each frame supports adjacent longitudinal segments along the length of each frame.

124. The modular endograft system of claim 112 wherein the first and second endograft devices each include at least one anchor at the superior portion, wherein the anchor protrudes radially from the outer wall in the expanded configuration and constricts in a low-profile configuration.

125. The modular endograft system of claim 112 wherein:
the first endograft device further includes a first transition portion between the first superior portion and the first inferior portion, the first transition portion tapering the first lumen from a first cross-sectional dimension at the superior portion to a second cross-sectional dimension less than the first cross-sectional dimension at the inferior portion, wherein the transition portion is configured to maintain substantially laminar blood flow through the first lumen in the expanded configuration; and the second endograft device further includes a second transition portion between the second superior portion and the second inferior portion, the second transition portion tapering the second lumen from the first cross-sectional dimension at the second superior portion to the second cross-sectional dimension at the second inferior portion, wherein the second transition portion is configured to maintain substantially laminar blood flow through the second lumen in the expanded configuration.

126. The modular endograft system of claim 112 wherein:
the first endograft device has a first frame and a first cover attached to a portion of the first frame, the first frame comprising an open braided wire, and the first cover having a first opening at the first outer wall;
the second endograft device has a second frame and a second cover attached to the second frame, the second frame comprising an open braided wire, and the second cover having a second opening at the second outer wall; and wherein the first and second openings allow blood to flow laterally relative to the first and second lumens.

127. The modular endograft system of claim 112 wherein:
the first endograft device has a first frame and a first cover attached to a portion of the first frame, the first frame comprising an open braided wire, and the first cover having a first opening at the first inferior portion, and wherein the first opening allows blood to flow laterally through the first opening relative to the first lumen.

128. A modular endograft system, comprising:
a first endograft device having a first frame, a first cover attached to the first frame, and a first lumen within the first cover, wherein the first frame and the first cover have a first superior portion and a first inferior portion, and the first superior portion has a convexly curved first outer wall and a first septal wall;
a second endograft device having a second frame, a second cover attached to the second frame, and a second lumen within the second cover, wherein the second frame and the second cover have a second superior portion and a second inferior portion, the second superior portion having a convexly curved second outer wall and a second septa[ wall;
wherein the first and second endograft devices are configured to be extended into a low-profile configuration with a first cross-sectional dimension and expand to an expanded configuration with a second cross-sectional dimension greater than the first cross-sectional dimension such that in the expanded configuration opposing portions of the first and second septal walls press against each other and form a septum between the first and second lumens; and wherein the first and second endograft devices are longitudinally staggered with respect to the each other in the expanded configuration such that the first frame includes a first free end portion projecting distally beyond the second superior portion of the second endograft device.

129. The modular endograft system of claim 128 wherein the first and second frames each include a superior terminus, an inferior terminus, and a continuous wire woven in a braid, the wire crossing itself at a braid angle, and the wire reversing direction at the superior terminus of the frame to form a first plurality of loops and reversing direction at the inferior terminus of the frame to form a second plurality of loops

130. The modular endograft system of claim 129 wherein the braid angle is from approximately 30° to approximately 45°.

131. The modular endograft system of claim 128 wherein:
the first superior portion has a cross-sectional dimension of at least 20 mm in the expanded configuration and a cross-sectional dimension of at most mm in the low-profile configuration; and the second superior portion has a cross-sectional dimension of at least 20 mm in the expanded configuration and a cross-sectional dimension of at most 5 mm in the low-profile configuration.

132. The modular endograft system of claim 128 wherein the first and second covers extend over the first and second frames, respectively, and wherein the first and second covers are configured to limit radial expansion and longitudinal contraction of the first and second frames in the expanded configuration.

133. The modular endograft system of claim 128 wherein:
the first cover includes first ribs protruding radially from the first frame in the expanded configuration, the first ribs being extendable longitudinally in the low-profile configuration;
the second cover includes second ribs protruding radially from the second frame in the expanded configuration, the second ribs being extendable longitudinally in the low-profile configuration; and wherein the first and second ribs interface at the septum in the expanded configuration.

134. The modular endograft system of claim 128 wherein:
the first and second superior portions include alignment aids on opposing first and second septal walls, the alignment aids being configured to cross one another when the first and second septal walls form the septum.

135. The modular endograft system of claim 128 wherein:
the first frame comprising an open braided wire and the first cover having a first opening at the first outer wall;
the second frame comprising an open braided wire, and the second cover having a second opening at the second outer wall; and wherein the first and second openings allow blood to flow laterally relative to a longitudinal axis of the first lumen and second lumens.

136. The modular endograft system of claim 135 wherein the first cover of the first endograft device has a third opening at the first inferior portion, and wherein the third opening allows blood to flow laterally through the third opening from the first lumen.

137. A method of repairing an aneurysm in a primary blood vessel before a bifurcation into a first blood vessel and a second blood vessel, comprising:
advancing a first endograft device through the first blood vessel to a target site in the primary blood vessel before the aneurysm;
advancing a second endograft device through the second blood vessel to the target site independently of advancing the first endograft device through the first blood vessel;
deploying the first and second endograft devices at the target site by separately expanding the first and second endograft devices to an expanded configuration such that opposing portions of first and second septal walls of the first and second endograft devices, respectively, press against each other to form a septum between the first and second endograft devices; and wherein a first superior portion of the first endograft device is longitudinally staggered relative to a second superior portion of the second endograft device such that a free end portion of the first superior portion projects distally beyond a terminus of the second endograft device.

138. The method of claim 137, further comprising:
loading the first endograft device in a first catheter, wherein the first endograft device is extended in a low-profile configuration;
loading the second endograft device in a second catheter, wherein the second endograft device is extended in a low-profile configuration;
percutaneously introducing the first endograft device into the first blood vessel; and percutaneously introducing the second endograft device into the second blood vessel.

139. The method of claim 138 wherein the first and second endograft devices have a cross-sectional dimension no less than 20 mm in the expanded configuration, and wherein the first and second catheters are no larger than 12 F.

140. The method of claim 137 wherein the first endograft device includes a first alignment aid at the first septal wall and the second endograft device includes a second alignment aid at the second septal wall, the first and second alignment aids comprising a radiopaque material, and wherein deploying the first and second endograft devices further includes:
radiographically positioning the first and second alignment aids such that the first and second alignment aids oppose one another;
viewing the first and second alignment aids in the orthogonal plane; and crossing the first and second alignment aids such that the first and second septal walls form the septum.

141. The method of claim 140 wherein the first and second alignment aids diagonally cross the first and second septal walls, and wherein the first and second alignment aids form an "X" indicator at the septum.

142. The method of claim 137 wherein the first and second endograft devices each include a frame and a cover, at least a portion of the cover being attached over the frame, and at least a portion of the cover having a plurality of circumferential ribs projecting radially from the frame, and wherein deploying the first and second endograft devices further comprises:
interfacing the circumferential ribs at the first septal wall with the circumferential ribs at the second septal wall at the septum; and interfacing the circumferential ribs at the first and second outer walls with a vessel wall of the primary blood vessel.

143. The method of claim 137 wherein the first and second endograft devices each include a cover attached over at least a portion of a frame, and deploying the first and second endograft devices further comprises restricting radial expansion of the frames with the covers.

144. The method of claim 137 wherein the primary blood vessel is an aorta and the first blood vessel is a first common iliac artery and the second blood vessel is a second common iliac artery, and wherein deploying the first and second endograft devices further includes:
at least substantially sealing a proximal end of a first inferior portion of the first endograft device with an arterial wall of the first common iliac artery;
and at least substantially sealing a proximal end of a second inferior portion of the second endograft device with an arterial wall of the second common iliac artery.

145. The method of claim 137 wherein the first septal wall is convexly curved in a direction opposite a first outer wall of the first endograft device and a second septal wall of the second endograft device is convexly curved in a direction opposite the second outer wall, and wherein deploying the first and second endograft devices comprises urging opposing portions of the convexly curved first and second septal walls together.

146. The method of claim 145 wherein urging convexly the curved first and second septal walls together results in a substantially uniform distribution of pressure between the opposing portions of the first and second septal walls.

147. The method of claim 137 wherein the primary blood vessel includes a third blood vessel and a fourth blood vessel branching from the primary blood vessel before the aneurysm, the third and fourth blood vessels being longitudinally offset from one another relative to the primary blood vessel, and wherein:
the first endograft device has a first braided frame and a first cover coupled to the first braided frame, the first cover having a first inferior terminus and a first superior terminus, and the first braided frame having a first end extending distally beyond the first superior terminus of the first cover and second end extending proximally beyond the first inferior terminus of the first cover, wherein the first and second end portions include openings through which blood can flow laterally relative to a longitudinal axis of the first lumen;
the second endograft device has a second braided frame and a second cover attached to the second braided frame, the second cover having a second inferior terminus and a second superior terminus, and the second braided frame having a first end extending distally beyond the second superior terminus of the second cover and a second end extending proximally beyond the second inferior terminus of the second cover, wherein the first and second end portions include openings through which blood can flow laterally relative to a longitudinal axis of the second lumen; and staggering the first and second endograft devices comprises positioning the first end portion of the first frame at the entrance of the third blood vessel and positioning the first end portion of the second frame at the entrance of the fourth blood vessel such that the third and fourth blood vessels are in fluid communication with blood flow through the first and the second lumens.

148. The method of claim 137 wherein the primary blood vessel includes a third blood vessel and a fourth blood vessel branching from the primary blood vessel before the aneurysm, the third and fourth blood vessels being longitudinally offset from one another relative to the primary blood vessel, and wherein:
the first endograft device includes a first frame and a first cover attached to a portion of the first frame, the first frame comprising an open braided wire, and the first cover having a first opening at the first outer wall;
the second endograft device includes a second frame and a second cover attached to the second frame, the second frame comprising an open braided wire, and the second cover having a second opening at the second outer wall, wherein the first and second openings allow blood to flow laterally relative to a longitudinal axis of the first and second lumens; and staggering the first and second endograft devices comprises positioning the first opening of the first frame at the entrance of the third blood vessel and positioning the second opening of the second frame at the entrance of the fourth blood vessel such that the third and fourth blood vessels are in fluid communication with blood flow through the first and the second lumens.

149. The method of claim 137 wherein the first blood vessel includes a third blood vessel branching from the first blood vessel after the aneurysm, and wherein:
the first endograft device includes a first frame and a first cover attached to a portion of the first frame, the first frame comprising an open braided wire, and the first cover having a first opening at the first inferior portion; and the method further comprises positioning the first opening of the first frame at the entrance of the third blood vessel such that blood from the first lumen flows laterally through the first opening to the third blood vessel.

150. The method of claim 137 wherein the first and second endograft devices include first and second frames, respectively, and the first and second frames are configured to provide continuous support such that the free end portion at least substantially aligned with the first septal wall at the septum.

151. A modular endograft system, comprising:
a cuff having a proximal end portion and a distal end portion;
a first endograft device having a first superior portion, a first inferior portion, and a first lumen through the first superior and inferior portions, wherein the first superior portion has a first outer wall and a first septal wall;
a second endograft device having a second superior portion, a second inferior portion, and a second lumen through the second superior and inferior portions, wherein the second superior portion has a second outer wall and a second septal wall; and wherein the first and second endograft devices are configured such that the first and second outer walls of the first and second endograft devices press against the cuff and the first and second septal walls exert opposing forces toward one another to fix the cuff to the first and second lumens.

152. The modular endograft system of claim 151 wherein the cuff has a substantially circular cross section and at least one of the proximal and distal end portions of the cuff is flared radially outward.

153. The modular endograft system of claim 151 wherein the cuff includes a cuff frame having a proximal terminus and a distal terminus and a sleeve radially inward from the cuff frame, wherein the sleeve extends over the proximal and distal termini of the cuff frame.

154. The modular endograft system of claim 151 wherein:
the cuff includes a sleeve and a cuff frame at least partially enclosing the sleeve;
the sleeve bifurcates the cuff into a first cuff lumen and a second cuff lumen;
and the first superior portion of the first endograft device contacts the first cuff lumen and the second superior portion of the second endograft device contacts the second cuff lumen.

155. The modular endograft system of claim 151 wherein the first and second superior portions of the first and second endograft devices, respectively, project distally beyond the distal end portion of the cuff such that portions of the first and second outer walls of the endograft devices affix to an adjacent vessel wall.

156. The modular endograft system of claim 151 wherein:
the first superior portion of the first endograft device includes a convexly curved first outer wall having a first radius and a convexly curved first septal wall having a second radius greater than the first radius such that the first superior portion has a D-like cross-section;
the second superior portion of the second endograft device includes a convexly curved second outer wall having the first radius and a convexly curved second septal wall having the second radius such that the second superior portion has a D-like cross-section;
wherein the first and second outer walls press against the cuff device in an expanded configuration; and the first and second septal walls press against each other in the expanded configuration and form a septum, and the convex curvature of the first and second septal walls results in a substantially uniform distribution of pressure along the septum.

157. The modular endograft system of claim 156 wherein:
the first septal wall and the first outer wall are joined at curved corners;
the second septal wall and the second outer wall are joined at curved corners;

and the curved corners have a radius of curvature less than the first radius, and wherein the curved corners form an angle from approximately 60° to approximately 100° at the septum in the expanded configuration.

158. The modular endograft system of claim 151, further comprising at least one anchor coupled to an exterior of the cuff, wherein the anchor protrudes radially from the cuff in an expanded configuration and constricts in a low-profile configuration.

159. The modular endograft system of claim 151 wherein the first and second endograft devices include at least one anchor at the first and second superior portions, wherein the anchor protrudes radially from the superior portions in an expanded configuration.

160. The modular endograft system of claim 151 wherein:
the first endograft device includes a first alignment aid at the first septal wall;
and the second endograft device includes a second alignment aid at the second septal wall, wherein the second alignment aid crosses the first alignment aid when the first and second septal walls of the first and second endograft devices, respectively, oppose one another such the first and second septal walls form a septum.

161. The modular endograft system of claim 151 wherein:
the cuff includes a first cuff alignment aid and a second cuff alignment aid;
the first endograft device includes a first alignment aid at the first outer wall, wherein the first alignment aid crosses the first cuff alignment aid when the first outer wall opposes the cuff; and the second endograft device includes a second alignment aid at the second outer wall, wherein the second alignment aid crosses the second cuff alignment aid when the second outer wall opposes the cuff.

162. The modular endograft system of claim 151 wherein:
the first endograft device further includes a first transition portion between the first superior portion and the first inferior portion, the first transition portion tapering the first lumen from a first cross-sectional dimension at the superior portion to a second cross-sectional dimension less than the first cross-sectional dimension at the inferior portion, wherein the transitional portion is configured to maintain substantially laminar blood flow through the first lumen in an expanded configuration;
the second endograft device further includes a second transition portion between the second superior portion and the second inferior portion, the second transition portion tapering the second lumen from the first cross-sectional dimension at the second superior portion to the second cross-sectional dimension at the second inferior portion, wherein the second transitional portion is configured to maintain substantially laminar blood flow through the second lumen in the expanded configuration; and the cuff further includes a transitional cuff portion at the proximate end portion, the tapered cuff portion being substantially conformal to the first and second tapered transitional portions.

163. The modular endograft system of claim 151 wherein the first and second endograft devices each include a frame having a superior terminus, an inferior terminus, and a continuous wire woven in a braid, the wire crossing itself at a braid angle, and the wire reversing direction at the superior terminus of the frame to form a first plurality of loops and reversing direction at the inferior terminus of the frame to form a second plurality of loops.

164. The modular endograft system of claim 163 wherein the first and second endograft devices each further include a cover over at least a portion of the frame, the cover having circumferential ribs protruding radially from the frame such that opposing circumferential ribs of the first and second septal walls mate in the expanded configuration.

165. A modular endograft system, comprising:
a cuff having a cuff frame and a sleeve attached to the cuff frame, wherein the cuff frame and the sleeve have a proximal end portion and a distal end portion;

a first endograft device having a first frame, a first cover attached to the first frame, and a first lumen within the first cover, wherein the first frame and the first cover have a first superior portion and a first inferior portion, and the first superior portion has a convexly curved first outer wall and a first septal wall;
a second endograft device having an integrated second frame ("second frame"), a second cover attached to the second frame, and a second lumen within the second cover, wherein the second frame and the second cover have a second superior portion and a second inferior portion, the second superior portion having a convexly curved second outer wall and a second septal wall; and wherein the first and second endograft devices are configured to be extended into a low-profile configuration with a first cross-sectional dimension and expand to an expanded profile configuration with a second cross-sectional dimension greater than the first cross-sectional dimension such that in the expanded configuration the first and second septal walls are urged toward each other and form a septum between the first and second lumens and the first and second outer walls press against an interior of the cuff.

166. The modular endograft system of claim 165 wherein at least one of the proximal and distal end portions of the cuff frame is flared radially outward.

167. The modular endograft system of claim 166 wherein the sleeve extends over proximal and distal ends of the cuff frame such that the sleeve attaches to the cuff frame when the cuff presses against vessel walls.

168. The modular endograft system of claim 165 wherein the sleeve includes a first cuff lumen configured to receive the first endograft device and a second cuff lumen configured to receive the second endograft device.

169. The modular endograft system of claim 165 wherein the first and second endograft devices are staggered longitudinally relative to the first and second lumens such that the first superior portion includes a free end portion projecting distally beyond the second superior portion of the second endograft device.

170. The modular endograft system of claim 165 wherein the first and second frames each include a superior terminus, an inferior terminus, and a continuous wire woven in a braid, the wire crossing itself at a braid angle, and the wire reversing direction at the superior terminus to form a first plurality of loops and reversing direction at the inferior terminus to form a second plurality of loops

171. The modular endograft system of claim 170 wherein the braid angle is from approximately 30° to approximately 45°.

172. The modular endograft system of claim 170 wherein the wire has a diameter from approximately 0.0070 inch to approximately 0.0140 inch and the first plurality of loops includes no more than eight loops and the second plurality of loops includes no more than eight loops.

173. The modular endograft system of claim 165 wherein the first and second covers extend over the first and second frames, and wherein the first and second covers limit at least one of radial expansion and longitudinal contraction of the first and second frames, respectively, in the expanded configuration.

174. The modular endograft system of claim 165 wherein:
at least a portion of the sleeve is radially inward from the cuff frame, and wherein the sleeve includes ribs protruding radially inward from the cuff frame;
the first cover includes first ribs protruding radially from the first frame in the dilated configuration, the first ribs being extendable longitudinally in the low-profile configuration;
the second cover includes second ribs protruding radially from the second frame in the dilated configuration, the second ribs being extendable longitudinally in the low-profile configuration; and wherein the first and second ribs interface with the ribs of the sleeve in the expanded configuration.

175. The modular endograft system of claim 165, further comprising at least one anchor protruding radially outward from an exterior of the cuff.

176. The modular endograft system of claim 165 wherein the first and second superior portions include alignment aids on opposing first and second septal walls, the alignment aids being configured to cross one another when the first and second septal walls form the septum.

177. A method of repairing an aneurysm in a primary blood vessel before a bifurcation into a first blood vessel and a second blood vessel, comprising:
advancing a cuff through the first blood vessel to a target site in the primary blood vessel before the aneurysm, the cuff having a substantially circular cross-section;
deploying the cuff at the target site such that the cuff presses against a vessel wall of the primary blood vessel;
advancing a first endograft device through the first blood vessel to a target site in the common blood vessel before the aneurysm;
advancing a second endograft device through the second blood vessel to the target site;
deploying the first and second endograft devices at the target site such that the first and second endograft devices expand to an expanded configuration via inherent spring forces in the first and second endograft devices such that first and second septal walls of the first and second endograft devices, respectively, press toward each other and form a septum between the first and second endograft devices, and wherein first and second outer walls of the first and second endograft devices, respectively, sealably press against an interior surface of the cuff; and wherein the first and second endograft devices are positioned independently of one another.

178. The method of claim 177 wherein positioning the first and second endograft devices independently comprises:
positioning a first superior portion of the first endograft device in a first desired position within the cuff; and positioning a second superior portion of the second endograft device in a second desired position within the cuff, wherein the first desired position is longitudinally offset from the second desired position along the cuff.

179. The method of claim 177, further comprising:
loading the first endograft device in a first catheter, wherein the first endograft device is extended in a low-profile configuration;
loading the second endograft device in a second catheter, wherein the second endograft device is extended in a low-profile configuration;
percutaneously introducing the first endograft device into the first blood vessel; and percutaneously introducing the second endograft device into the second blood vessel.

180. The method of claim 179 wherein the first and second endograft devices have a cross-sectional dimension no less than 20 mm in the dilated configuration, and wherein the first and second catheters are no larger than 12 F.

181. The method of claim 177 wherein the first endograft device includes a first alignment aid at the first septal wall and the second endograft device includes a second alignment aid at the second septal wall, the first and second alignment aids comprising a radiopaque material, and wherein deploying the first and second endograft devices further includes:
radiographically positioning the first and second alignment aids such that the first and second alignment aids oppose one another;
viewing the first and second alignment aids in the orthogonal plane; and crossing the first and second alignment aids such that the first and second septal walls can form the septum.

182. The method of claim 181 wherein the first and second alignment aids diagonally cross the first and second septal walls, and wherein the first and second alignment aids form an "X" indicator at the septum.

183. The method of claim 177 wherein the cuff includes a cuff frame and an internal sleeve having ribs protruding radially inward from the cuff frame, the first and second endograft devices each include a cover having a plurality of circumferential ribs at least at the first and second septal and outer walls of the first and second endograft devices, respectively, and wherein deploying the first and second endograft devices further comprises:
interfacing the circumferential ribs at the first septal wall with the circumferential ribs at the second septal wall; and interfacing the circumferential ribs at the first and second outer walls with the ribs of the internal sleeve.

184. The method of claim 177 wherein the first and second endograft devices each include a cover attached over at least a portion of a frame, and deploying the first and second endograft devices further comprises restricting radial expansion of the frames with the covers.

185. The method of claim 177 wherein the primary blood vessel is an aorta and the first blood vessel is a first common iliac artery and the second blood vessel is a second common iliac artery, and wherein deploying the cuff and the first and second endograft devices further includes:
at least substantially sealing the cuff with an arterial wall of the aorta;
at least substantially sealing the first inferior portion with an interior arterial wall of the first common iliac artery; and at least substantially sealing the second inferior portion with an interior arterial wall of the second common iliac artery.

186. The method of claim 177 wherein the primary blood vessel includes a third blood vessel and a fourth blood vessel branching from the primary blood vessel before the aneurysm, the third and fourth blood vessels being longitudinally offset from one another relative to the primary blood vessel, and wherein:
the first endograft device has a first braided frame and a first cover coupled to the first braided frame, the first cover having a first inferior terminus and a first superior terminus, and the first braided frame having a first end extending distally beyond the first superior terminus of the first cover and second end extending proximally beyond the first inferior terminus of the first cover, wherein the first and second end portions include openings through which blood can flow laterally relative to a longitudinal axis of the first lumen;
the second endograft device has a second braided frame and a second cover attached to the second braided frame, the second cover having a second inferior terminus and a second superior terminus, and the second braided frame having a first end extending distally beyond the second superior terminus of the second cover and a second end extending proximally beyond the second inferior terminus of the second cover, wherein the first and second end portions include openings through which blood can flow laterally relative to a longitudinal axis of the second lumen;
deploying the cuff comprises positioning the cuff proximal to the third and fourth blood vessels; and deploying the first and second endograft devices comprises positioning the first end portion of the first frame at the entrance of the third blood vessel and positioning the first end portion of the second frame at the entrance of the fourth blood vessel such that the third and fourth blood vessels are in fluid communication with blood flow through the first and the second lumens.