CN100457206C

CN100457206C - Adjustable pulsatile myocardial internal injector

Info

Publication number: CN100457206C
Application number: CNB2007100378655A
Authority: CN
Inventors: 张�浩; 宋智钢; 徐志云
Original assignee: Second Military Medical University SMMU
Current assignee: Second Military Medical University SMMU
Priority date: 2007-03-07
Filing date: 2007-03-07
Publication date: 2009-02-04
Anticipated expiration: 2027-03-07
Also published as: CN101015717A

Abstract

This invention relates to an adjustable pulsation myocardial infuser comprising needle cylinder, pintle, pinhead, regulating ring, and external casing. Regulating ring can endwise slip along needle cylinder, and is provided with locking screw. External casing is inserted to needle cylinder by pinhead direction to regulating ring, and pinhead can penetrate rubber joint in front of the external casing. The exposed pinhead part is the length pierce into centrum. Needle cylinder wall adopts double scale mark (volume and length), which can simultaneous control injection amount and needle insertion in acupuncture depth. The front end of the pintle piston is diving shagreen, and can reduce residual dead space. The pinhead needle cylinder is fixed through screw thread. The invention can prevent hemorrhage at pinhole and spillage of infusion, regulate effective pinhead length, thus is suitable for varisized cardiac with different myocardial thickness, effectively avoid penetrate myocardial. The invention has simple operation, and good practicability.

Description

Adjustable pulsatile myocardial internal injector

Technical field

The invention belongs to clinical medicine and research field, particularly a kind of adjustable pulsatile myocardial internal injector that is used in the pulsatile myocardial tissue, carrying out cell transplantation and the implantation of range gene carrier.

Background technology

Cell transplantation technology and gene technology are aspect all kinds of heart diseases of treatment at present, obtained application more and more widely, as to treating ischemic cardiomyopathy from chamber, body-centered intramuscular bone marrow stem cell or from room, body-centered myocyte, plantation embryonic stem cell and embryonic myocardium cell are rebuild the cardiac pacing kitchen range in the allosome ventricular muscles, to treat all kinds of slow arrhythmias; All kinds of genophores that will carry the various objectives gene by gene technology are injected directly in the cardiac muscle, or are re-introduced in the cardiac muscle behind the transfection target cell, explore the new method of treatment heart disease.Entered clinical experimental stage with the top therapeutic scheme.Use above-mentioned technology with infusion entad intramuscular inject when transplanting, take in open chest surgery more, down infusion is expelled to method in the pulsatile myocardial in direct-view, that this method has is simple to operate, inject advantages such as effect is certain.And present experimenter and clinician adopt disposable TB empty needle (tuberculin syringe) as implantation tool in this operating process mostly.TB empty needle needle point is tiny, scale is accurate, thus have myocardial damage little, advantage such as be easy to quantitatively.Yet, in pulsatile myocardial, injected its particularity, promptly pulsatile myocardial is under the kinestate of constantly contraction and diastole, and frequency very fast (60～120 times/minute); Blood fortune is abundant in the cardiac muscle, and is very easily hemorrhage and cause injected material to be overflowed losing after the withdraw of the needle; Cardiac muscle inside is the chambers of the heart, as injects deeply then that injected material enters the chambers of the heart, causes severe complications such as blood vessel embolism.And infusion (as cell suspension) is comparatively sticky usually, and TB empty needle needle point is tiny, and resistance is bigger during injection, causes syringe needle to eject sometimes and thrusts the chambers of the heart, and infusion overflows from disengagement simultaneously, causes injecting failure.

Obviously, disposable TB empty needle can't satisfy above-mentioned specific (special) requirements.Given this plant situation, be necessary to design a kind of special injection device that is more suitable in pulsatile myocardial, to solve the above-mentioned problem that exists and to reach every specification requirement required when injecting.

Summary of the invention

Technical problem to be solved by this invention is to overcome existing defective and deficiency, is to provide a kind of adjustable pulsatile myocardial internal injector that is more suitable in pulsatile myocardial.

Technical scheme of the present invention is as follows:

A kind of adjustable pulsatile myocardial internal injector comprises syringe, pintle, and syringe needle, adjustable ring, trocar sheath,

Syringe has adjustable ring outward, and adjustable ring can slide along needle cylinder wall, and adjustable ring is provided with lock screw;

Syringe has trocar sheath outward, and the trocar sheath front end has rubber blanket;

Syringe needle was fixed with being connected by screw thread of syringe;

The piston nose of pintle is for stretching into the formula projection;

The double scale labelling is arranged, i.e. volume markings and length scale on the needle cylinder wall;

The long 3cm of syringe needle, syringe needle bore 0.5～1.0mm.

Described syringe needle passes the trocar sheath rubber blanket, and the needle length c that ventricular muscles is thrust in its adjusting satisfies formula: c=a-b, and wherein, a is the distance of needle point to the adjustable ring front end, b is the trocar sheath total length.

Adjustable ring of the present invention can endwisely slip along needle cylindrical unit, and adjustable ring is provided with lock screw, adjustable ring can be firmly secured to the default scale place of syringe outer wall, thereby realize exposing the accurate control of needle length.Trocar sheath is inserted in syringe to adjustable ring by the syringe needle direction, syringe needle passes trocar sheath front end rubber blanket, its syringe needle that exposes partly is the length that can thrust ventricular muscles, because the trocar sheath rear end is conditioned the ring restriction, therefore its needle length that exposes promptly is fixed, can avoid in the cardiac muscle inserting needle to cross dark and penetrate ventricle wall, make infusion directly enter the chambers of the heart, cause after the severe complication of blood vessel embolism and the withdraw of the needle that the chambers of the heart is hemorrhage to be difficult to danger such as control.After inject finishing to withdraw from syringe needle, can reach the hemostasis of compressing cardiac muscle by the rubber blanket of trocar sheath and front end thereof and prevent the purpose that infusion overflows in the cardiac muscle.

The pintle front end is for stretching into the formula projection, can effectively reduce the residual dead space in injection back, avoids causing problems such as the waste of infusion and bubble formation.Syringe needle was fixed with being connected by screw thread of syringe, can prevent effectively that syringe needle from throwing off or ejection.Needle cylinder wall adopts double scale labelling (volume markings and length scale), helps controlling the infusion amount, and the position of regulating and controlling ring and trocar sheath, exposes needle length (being depth of needle) with indirect control.Syringe needle adds and grows to 3cm, can make needling length that more abundant range of accommodation is arranged, thereby satisfies the needs when being applied to the different-thickness cardiac muscle; Syringe needle bore 0.5～1.0mm can guarantee that infusion is smooth and easy to enter cardiac muscle by syringe needle.

The present invention has the following advantages as a kind of adjustable pulsatile myocardial internal injector:

1, can regulate and expose needle length, thereby be widely used in the heart of all size and different myocardial thickness, effectively avoid penetrating cardiac muscle and the danger that is strayed into the chambers of the heart.

2, utilize this infusion appliance can effectively prevent the overflowing of hemorrhage and injected material (as cell, gene and carrier thereof) at pinprick place.

3, pinhead wall is thin, and bore is relatively large, cell etc. by the time be difficult for being squeezed damage and can smooth and easyly passing through.

4, Gai Liang pintle front end stretches into the formula projection, can avoid causing the waste and the bubble formation of injected material (cell etc.).

5, syringe and syringe needle prevent because of injecting the sticky danger that causes syringe needle to be deviate from of liquid by being threaded.

6, can once finish whole injection process, operate quick, convenient.

7, whole device is convenient to operation, and is practical, uses when being specially adapted to inject in the pulsatile myocardial.

Description of drawings

Fig. 1 is a structural upright cutaway view of the present invention;

Fig. 2 is a front view of the present invention;

Fig. 3 is structure master's cutaway view of the present invention;

Fig. 4 is the trocar sheath cutaway view;

Fig. 5 is the infusion appliance cutaway view;

Fig. 6 is the adjustable ring schematic perspective view;

Fig. 7 is that figure cuts open in adjustable ring side-looking office.

The specific embodiment

Provide the embodiment of an adjustable pulsatile myocardial internal injector of the present invention below according to Fig. 1-Fig. 3, and described in detail, so that those skilled in the art are easier to understand architectural feature of the present invention and function characteristics, rather than be used for limiting scope of the present invention.

See also Fig. 1-Fig. 7, as shown in the figure:

A kind of adjustable pulsatile myocardial internal injector of the present invention comprises syringe 1, pintle 2, and syringe needle 7, the infusion appliance that adjustable ring 3 and trocar sheath 5 are formed, the pintle 2 in the syringe 1, its pintle front end stretches into the dead space that formula projection 6 is used to reduce syringe; Syringe needle 7 is fixedlyed connected by screw thread 8 with syringe 1; The syringe 1 outer adjustable ring 3 that is with, adjustable ring 3 can be regulated to moving along syringe 1 axon, and lock screw 4 is housed on the adjustable ring 3; Trocar sheath 5 is inserted in syringe 1 to adjustable ring 3 by syringe needle 7 directions, and syringe needle 7 passes trocar sheath 5 front end rubber blankets 9, and the syringe needle partial-length that it exposes is the length that can thrust ventricular muscles.

Implementation method of the present invention:

(1) opens and cut off behind the breast and suspend pericardium in midair, appear and intend the injection site ventricular muscles;

(2), determine the required needle length c that thrusts ventricular muscles according to heart size and ventricular muscles thickness;

(3) change its position along syringe 1 outer wall pusher collar 3, adjustable ring 3 front ends are alignd with syringe 1 outer wall scale (c), and [this scale c is the needle length of the thrust ventricular muscles that exposes, (a is the distance of needle point to the adjustable ring front end to c=a-b, b is the trocar sheath total length)], tighten screw 4 on the adjustable ring 3 with secured adjusted ring 3;

(4) extract required infusion (as cell suspension etc.) with the infusion appliance that does not connect syringe needle 7, connect syringe needle 7 also to screw interface thread 8;

(5) trocar sheath 5 is inserted in infusion appliance by syringe needle 7 directions, makes infusion appliance syringe needle 7 pass trocar sheath 5 front end rubber blankets 9, trocar sheath 5 ends prop up adjustable ring 3, and the syringe needle that trocar sheath 5 front ends expose partly is the length c that can thrust ventricular muscles;

(6) will expose syringe needle 7 and thrust in the ventricular muscles of beating of intending the injection position, proficiency fixed jacket pipe 5 behind the pumpback depletion of blood, another hand propelled pintle 2 makes infusion be entered in the ventricular muscles by syringe 1;

(7) after injection is finished, proficiency is fixed jacket pipe 5 still, and another hands is extracted trocar sheath 5 simultaneously with infusion appliance and syringe needle 7, continues fixed jacket pipe 5 and also gives modest pressure, make its front end rubber blanket 9 compressing ventricle wall remove trocar sheath 5 after about 0.5 to 1 minute, whole injection process finishes.

Claims

1. an adjustable pulsatile myocardial internal injector comprises syringe (1), pintle (2), and syringe needle (7), adjustable ring (3), trocar sheath (5) is characterized in that:

1) syringe (1) is outer adjustable ring (3), and adjustable ring (3) can slide along needle cylinder wall, and adjustable ring (3) is provided with lock screw (4);

2) syringe (1) is outer trocar sheath (5), and trocar sheath (5) front end has rubber blanket (9);

3) syringe needle (7) is fixing with being connected by screw thread (8) of syringe (1);

4) piston nose of pintle (2) is for stretching into formula projection (6);

5) on syringe (1) wall double scale labelling is arranged, i.e. volume markings and length scale;

6) the long 3cm of syringe needle (7), syringe needle (7) bore 0.5～1.0mm.

2. adjustable pulsatile myocardial internal injector according to claim 1, it is characterized in that, described syringe needle (7) passes trocar sheath rubber blanket (9), the needle length c that ventricular muscles is thrust in its adjusting satisfies formula: c=a-b, wherein, a is the distance of needle point to adjustable ring (3) front end, and b is trocar sheath (a 5) total length.