CN100467127C - Storage container for analysis apparatus - Google Patents

Storage container for analysis apparatus Download PDF

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Publication number
CN100467127C
CN100467127C CNB991050126A CN99105012A CN100467127C CN 100467127 C CN100467127 C CN 100467127C CN B991050126 A CNB991050126 A CN B991050126A CN 99105012 A CN99105012 A CN 99105012A CN 100467127 C CN100467127 C CN 100467127C
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CN
China
Prior art keywords
storage container
cell
analytical equipment
test element
analytical
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Expired - Lifetime
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CNB991050126A
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Chinese (zh)
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CN1243041A (en
Inventor
K·-D·萨谢雷
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Roche Diagnostics GmbH
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Boehringer Mannheim GmbH
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Publication of CN1243041A publication Critical patent/CN1243041A/en
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    • GPHYSICS
    • G01MEASURING; TESTING
    • G01NINVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/483Physical analysis of biological material
    • G01N33/487Physical analysis of biological material of liquid biological material
    • G01N33/4875Details of handling test elements, e.g. dispensing or storage, not specific to a particular test method
    • G01N33/48778Containers specially adapted therefor, e.g. for dry storage

Abstract

This invention related to a storage container for holding analytical devices, the storage container being made of a rigid material and containing separate chambers in each of which at most one analytical device can be accommodated, wherein the chambers are in a regular geometric arrangement in relation to one another and each of the chambers has at least two opposite openings each sealed by a foil, wherein at least one of the chambers comprises a means for fixing the position of an analytical device in the chamber. In addition the invention concerns a system for storing analytical devices containing a storage container according to the invention and two or more analytical devices.

Description

The storage container that analytical equipment is used
The present invention relates to a kind of storage container that can use for two or several analytical equipments of making by rigid material, these devices can be received into separately in the cell in this container, and these cells be connected to each other the rule geometrical relationship arranging, each cell has at least two holes that sealed by paper tinsel at that time.The invention still further relates to a kind of system that is used for the inventory analysis device, this system contains one according to storage container of the present invention and two or several analytical equipments.
Test fast at the indoor joint vector (carrier-bound) of now having set up of the dedicated experiments of chemical analysis that carries out solid and liquor sample and biochemical analysis, and this method also is used outside standing laboratory especially.Although comprise the complicated reaction of being generally of sensitive reagents, this based on special development dry chemical and set up joint vector fast test be simple and and uncomplicated, even can be finished by the layman.The joint vector fast foremost example of test is the test bar that is used for determining diabetic's blood glucose content.Single district that urinalysis is used or multi-region test bar and various indication paper also are known.Because except bar form (test bar), also there are other forms in the quick test of joint vector, so these carriers are commonly referred to as " analytical test element ".
The quick test of dry chemical joint vector has multi-layer packaging usually so that sell to the terminal use.Test is in its ground floor packing of direct encirclement (first packing) usually fast, this packing is placed on another packing (external packing again, second packing) in, in this packing, except first packing, contains the quick test operation indication of form usually for the packing insert.The designing institute basic function that will satisfy of first packing be will storage over a long time in make chemical composition and biochemical component on test element keep its function; protect these functions to make them not be subjected to the influence of light in a word; do not invaded, and the protection test element makes it not be subjected to the infringement of machinery by moisture, dirt, bacterium and dust in the atmosphere.
The modal a kind of form of first packing is that test element loosely that it is provided is contained in aluminum pipe or the plastic tube and should be pressed into or screws with screw thread by an effective block.The function of above-mentioned first packing can satisfy satisfactorily with these tube packagings.But these tube packagings are like out-of-date, because will take this test element respectively away more complicated in manually packing from first, why Here it is will develop the cause of other packing way.Except the top performance of mentioning, thereby these packings should make test element take away and directly to be fed to from packing on the measuring instrument by this apparatus measures and evaluation test result separately and automatically in addition.
European patent EP-A 0,622 119 has narrated the storage system of using for the strip test element, made by the material that water and steam are all sealed of rigidity, and wherein test element is stored in the cell of paper tinsel encapsulation (encapsulation separately) individually.The cell of storage test bar (another title of strip test element), it is shaped as the pipe with rectangular cross section, these pipes are gone up well-regulated mode by how much and are aligned mutually, cause the form of storage system to be essentially the storehouse of cuboid or hinged box, there are a plurality of parallel cells side by side to be arranged on the line in it, perhaps make this system become the shape of tall and thin drum type brake flat-disk, each cell is radially arranged around central axis.Test element can be taken away from storage system with manual or mechanical device, and the test element of staying in the storage container continues to be subjected to the protection of encapsulation separately.EP-A0622119 has also described the possibility that drier such as silica gel and molecular sieve are provided to test bar in cell in addition, in order that be absorbed in moisture remaining in the manufacture process of test bar, or in sealing with adopt the moisture that still is penetrated under the condition of waterproof steam material in the cell.Side in the storage system outside can link a data medium, the for example label of a readable formula, a bar code label or a magnetic strips, storing the concrete data of this batch of test element and other optional information in the system on it, they can be called again.Some storage containers of test element of explanation are suitable on the measuring system appropriate design, that be made up of measuring instrument, storage container and test element basically in EP-A 0 622119.
European patent EP-A 0 732 590 and U.S. Pat 5,489,414 have been narrated the discoid storage container that test element is used, and this container is suitable for blood sugar that small and exquisite measuring instrument for example uses by the diabetic especially from monitor.In this case, test element radially is arranged in the plane around disc centre and is encapsulated in separately in the bubble shape cover and makes it and dirt and moisture isolated, as the tablet of the known independent packing of people.Be provided with the bubble shape of separating cover that a drier uses and be connected together according to EP-A 0 732 590 each test element in storage container, can be dried effectively so that guarantee test element bubble shape cover with the bubble shape cover of test element.
From U.S. Pat 5,510,266 and European patent EP-A 0 738 666 have a kind of columnar test element storehouse system to be made of plastics as can be known with injection molding, wherein each test element is arranged in respectively from the cylinder bottom and is extended in the continuous cell of relative capping, and its situation is similar to the cartridge clip in the revolver rotating cylinder.The EP-A 0,622 119 that had mentioned in the above in addition, its test element is encapsulated in respectively in the parallel and tall and thin tubulose cell, these cells are radially arranged around a central longitudinal axis, and paper tinsel such as foil sealing are then used in the end of the circle of cylindrical storage container and the surface of lid.In order to take test element away in the storehouse, available plunger penetrates a sealed foil, and by the sealed foil of correspondence test element is released cell, so just can take test element away and it is fed on the required purposes.As EP-A 0 732 590, each test element chamber is provided with one separately and the desiccant chamber that is communicated with raceway groove, and the agent that just can be dried of test element chamber is dried reliably like this.US 5,510,266 and the test element storehouse of EP-A 0 738666 mainly also be to be designed on the small and exquisite measuring instrument.
A shortcoming of the storage container of above-mentioned prior art is that test element can not be the most protected as a means of the influence, particularly Ji Xie influence of resisting environment.At EP-A 0 732590 and US 5; 489; it is to be made by thin plastic foil that the bubble shape of the test element that illustrates in 414 is covered packing, and its performance makes it provide inappropriate protection consequently can not prevent mechanical infringement to test element, for example when packing is inadvertently pressurizeed or be crooked.In this case, US 5,510,266 and the test element storage container of EP-A 0 738 666 better protect can be provided because they are to be made by the solid material of rigidity, at least by force than bubble shape cover to pressurization and bending.But at US 5,510,266 and EP-A 0 738 666 in disclosed tubular package pattern its weakness is mechanically also arranged, promptly in order to make the test element chamber of sealing, adopt sealed foil that the end of cylinder and the surface of lid are sealed with sealed foil.These sealed foils are usually made with thin paper tinsel such as aluminium foil, in order that these paper tinsels are penetrated easily when will take test element away, but they for example also are damaged easily when packing and are inadvertently dropped or be placed on absent-mindedly when supporting upward.As long as,, thereby can cause severe impairment on sealed foil to the test element of packaged protection just it is indoor to make dust, bacterium and atmospheric water invade test element because a small opening is arranged.
Another shortcoming of the storage container of above-mentioned prior art be test element for example cause the inclination of test element in its cell by the regular meeting that removes automatically of plunger, so these systems are not fully reliably when providing test element.
The shortcoming of above-mentioned test element packaging scheme also can be used for other analytical equipments such as perverse blood pin or sampling element basically.Though these stream oriented devices do not contain sensitive reagents usually, need not protect to make it avoid ambient influnence, also must carefully make in the cell of storage container to be under the aseptic condition, stored like this element just can not become under longer storage and can not use.
The objective of the invention is to eliminate the shortcoming of prior art.Particularly an object of the present invention is to provide a kind of small and exquisite storage container is that test element, sampling element and lancet use for analytical equipment; they can be created at an easy rate in a large number; and guard bit analytical equipment within it reliably, make the ambient influnence that they avoid being harmful to such as the influence of light, moisture or machinery.In addition, storage container should be able to be become integrally to be attached to and make this system have small and exquisite measuring instrument, storage container and test element in the analytical system, can promptly inerrably take out analytical equipment reliably.
The present invention relates to a kind of storage container of being made by rigid material contains the analytical equipment of separating cell for two or several and uses, in each cell, admit a device at the most, each cell is being arranged with well-regulated geometrical relationship each other at that time, and each cell has at least two relatively and the hole that is sealed by paper tinsel, and each cell has a device to can be used to the fixedly position of analytical equipment in cell at that time.
Title " analytical equipment " is understood to include analytical test element, cuvette, dropper or lancet usually.Their suitable analytical test element or perverse blood pins of being called as, the especially suitable analytical test element that is called as.The meaning of analytical test element used herein is a test bar, and this test bar can wait by vision or optics, with instrument, electrochemical sensor and estimate.Since this analytical equipment in the prior art by broad description, for the expert is familiar with and numerous embodiment is arranged, no longer need detailed description here.Will with reference to the time for example can look for the following files: German patent application file number 197 53 8479, patent EP-A 0 138 152, EP-A 0 821 234, EP-A 0 821 233, EP-A 0 630 609, EP-A 0 565 970 and WO 97/02487.
Most of consistent according to shape, function and the material of storage container of the present invention with prior art.To should be mentioned that EP-A-0 622 119, EP-A-0 738 666 and US 5,510 266 especially.This paper is once clearly with reference to these files.
Have suitable especially shape according to storage container of the present invention, be essentially a tall and thin cylinder, wherein be used for keeping many cells of analytical equipment radially to arrange around longitudinal axis.The high length that depends on the analytical equipment that to be admitted basically of tube.The hole of many cells is contained on the end of cylindrical vessel and the surface of lid, and they are closely sealed by paper tinsel.Lip-deep all Kongzuis well individually and sealed independently of each other but are only used a slice paper tinsel.Had single and independently sealing, when a cell was opened, the sealed foil of all the other cells just can not be damaged.
Preferably make according to the main body of storage container of the present invention by rigidity, injection-molded plastics such as polyethylene or polypropylene.The paper tinsel that is used for sealing the cell eyelet is also referred to as sealed foil, preferably make by the lamination of aluminium or aluminium and plastics, and by with known method as being welded on the gluing plastic body that closely is attached at storage container.The most handy hot-melt adhesive of sealed foil is fixed on the injection-molded body.In order to prevent that adhesive residue from extending in the device cell or surmount the edge of storage container, according to a more excellent embodiment of the present invention, the zone of admitting adhesive residue can be set on single or all affected edges, for example can on all affected edges, circumferential groove be set so that admit adhesive residue.
Storing drier individually for each cell of analytical equipment in a preferential embodiment according to storage container of the present invention, this drier preferably is received within the separated desiccant chamber.All drier that become solid or pasty masses all can be used as drier particularly silica gel molecule cerium and similar material on principle.The size of desiccant chamber can be determined according to the quantity of the required drier of cell of dry erecting device.Drier cell and device cell will interknit gas can be exchanged.Their the most handy raceway grooves interconnect, and air can be exchanged between two cells, make device cell drying like this.The size of raceway groove and geometry are preferably arranged like this, and for example silica gel and molecular sieve can not enter in the device cell to make drier.Size that also must corresponding selection desiccant particles if desired.
The drier cell preferably contains two holes, and one of them is used for drier is filled to (input port) in the cell, and another provides contact to make the drier cell carry out gas exchange (ditch road junction) with the analytical equipment cell.The ditch road junction must all be held open if having time in institute at that time, in order that make device cell drying, and the input port can seal behind the drier of packing into.Like this carry out according to the present invention storage container for example subsequently manufacturing or can prevent that the accident of drier from escaping during the filling work step.The input port of drier cell can for example cover with card, paper, plastic foil or metal forming aptly and seal.Suit in addition to cover the input port with chock plug plastics or binding agent.The suitable especially chock plug with injection-molded material in the input port of drier cell seals, and chock plug is pushed in the hole from the marginal zone in hole by means of proper tools and just can forms port lid.
The main difference part of the storage container that the known analytical equipment of the present invention and prior art is used is, is provided with the facility that makes analytical equipment fix its position in cell in each is used for keeping the cell of single analytical equipment.Analytical equipment is fixed on the result is favourable astoundingly in the cell, because can prevent the infringement to paper tinsel like this, and paper tinsel is made independent sealing for each cell, so also can prevent the intrusion of moisture, dust, dirt and bacterium.When storage container was inadvertently dropped, shakes or collides, sealed foil can be staved by the analytical equipment in the storage container of prior art, because be unfixed at this container inner analysis device, therefore can move in cell.Adopt this container, when making, store, transporting and using storage container, can not guarantee that each cell has reliable sealing, the analytical equipment in cell also just can not obtain reliable protection like this.According to fixed-site the facility cell in of the present invention's introducing with analytical equipment, this problem has just solved.Analytical equipment is fixed on the analyzed device of sealed foil that can prevent cell in its cell widely inadvertently to be staved.
As the facility on the fixed position that analytical equipment is fixed in the cell, has various design according to the present invention.But except with stable manner in cell fixedly the position of analytical equipment, these facilities also must make analytical equipment easily be loaded in the cell, and can take away from cell again when needs use.
Confirm that once the priority facility that analytical equipment is fixed on the fixed position in the cell partly narrows down for making cell, this narrows down preferably in the zone relative with the analytical equipment conveying end of cell.It can be continuous in conical or progressively narrowing down, and analytical equipment can be fixed from one or several sides.Wall that the narrowing down of cell can be related to cell or at whole lip-deep several walls of cell.But cell also may have one or several protuberances towards little chamber interior to make the usefulness that narrows down at Qi Bishang.The shape of each protuberance can be that be equal to or different, and for example can be forms such as arch, bar, drum, prominent, rib.The protuberance of little locular wall has such effect, and analysis element just partly is touched in order to fix its position in cell, and the power that produces in the time of can making fixedly like this reaches optimum stage.
According to the present invention, confirmed already that it was to make the part of locular wall do conically to narrow down and make one or several protuberances on locular wall that analytical equipment is fixed on suitable especially way in the cell.Three ribs that are located on two relative locular walls are suitable to especially protuberance, and they are slightly crooked with the analytical equipment in the cell, utilize the bending stress that is produced that analytical equipment is fixed in its position.Should not damage the function of analytical equipment or weakening analytical equipment when crooked certainly.
In addition according to the present invention, confirmed already to be preferably in that to have only a hole at least in two holes according to each cell of storage container of the present invention be suitablely to be used for packing into and taking out analytical equipment.Only need have enough stool to take out analytical equipment by this hole in such two holes maybe is inserted into analytical equipment in the cell when loading.This performance in hole is called " can analyzed device penetrate " hereinafter for short.
(particularly EP-A 0 738 666 and US 5,510,266) penetrates in the hole of basal surface and the analytical equipment that can both be accommodated in the storage container in the hole of cap surface in the storage container of prior art.When installing to analytical equipment in the storage container according to said prior art, a surface of storage container is at first sealed by a paper tinsel, in the cell that subsequently a plurality of analytical equipments is installed to respectively for this reason and be provided with, last also with the paper tinsel face seal that this is still unlimited.The shortcoming of this method is, damages first paper tinsel easily when time in the cell that analytical equipment is packed into, and must cell could be sealed with two manufacturing work steps.And in according to more excellent storage container of the present invention, under any circumstance all have only a hole to penetrate by analyzed device at least two of cell holes, these shortcomings have not just existed.Cell can all not have before the sealing of sealed paper tinsel analytical equipment to be inserted in two holes, because a hole of cell can not penetrate by analyzed device, shelved the analytical equipment that inserts thereon with regard to the end that can be used as cell in this hole.Therefore the risk of damaging paper tinsel in this work step can reduce.Can carry out simultaneously in the both sides in hole with the process of paper tinsel sealing cell in addition.And can not lead to by analyzed device owing to the hole at this side cell at the sealed foil according to that side of storage container of the present invention continuously, therefore can not damaged or perverse wearing from the inboard by the analytical equipment in cell basically, the degree of reliability according to storage container of the present invention just can increase like this.
Preferably analytical equipment is released outside the cell according to of the present invention analytical equipment is taken out in the storage container by means of a plunger.For the preferred embodiment according to storage container of the present invention, wherein one of two holes of cell can not penetrate by analyzed device, and way is that this hole is penetrated by a plunger preferably, with this plunger analytical equipment is released outside the storage container then.Shi Yi way is that each cell all has a guide groove for the plunger setting especially.In push, just plunger and position can be remained on the relative position of correct qualification at analytical equipment in cell like this, thus can prevent that plunger and analysis element from tilting or one on another, slide.
In the time will taking out analytical equipment in cell, because the paper tinsel that is used for sealing according to storage container cell eyelet of the present invention must be able to be taken off from cell, they become naturally according to one of storage container of the present invention potential weakness mechanically.Just be restricted when the material of selecting paper tinsel and thickness like this, when plunger was pressed on the analytical equipment, sealed foil must be torn by the analytical equipment in the cell.When paper tinsel was torn, analytical equipment must not be damaged in addition.In order to protect these sealed foils; for example when storage container is placed in the flat supporting; once drew a kind of favourable way according to the present invention, that is exactly on the surface of the storage container that is sealed by paper tinsel protuberance to be set, so as to direct contact the between preventing paper tinsel and supporting.Can be designed to thin perimeter flange according to these protuberances of the present invention around the storage container periphery.At center protuberance is set and also is proved to be favourable according to the surface that is sealed by paper tinsel of storage container of the present invention.Protuberance can have for example hillock of rib or a plurality of regular distributions of any required shape.The height of protuberance depends on the thickness of used paper tinsel basically.The thickness that protuberance must have sealed foil at least adds sealed foil is fixed to presumable adhesive layer thickness on the storage container.But protuberance preferably has at least 300 to 400 microns to be projected into outside the surface of sealed foil.The preferably not sealed paper tinsel of swelling covers, and its region is preferably empty.Has suitable figure earlier before sealed foil is preferably on the main body that installs to storage container in this case.This sealed foil is installed need make sealed foil correctly locate with respect to the main body of storage container certainly.
Turned out to be particularly advantageous way already and be the surface that is provided with sealed foil according at least one of storage container of the present invention made and be not flat but become top downward shallow taper shape.This be use plunger with analytical equipment release in its cell the comparatively suitable surface that can pass through.Certainly also can make like this on the surface of the paper tinsel sealing on its opposite.The benefit of this trochoidal surface is to protect sealed foil not make it be subjected to accidental injury, because have only the neighboring can be shelved on the plane surface.Owing to this geometry, tear the required power of paper tinsel and can reduce in addition.Circular cone is suitably 1 ° to 45 ° angle to the gradient of plane surface, particularly 1 ° to 10 °, is preferably 5 °.
In storage container or on be provided with suitable facility so that remain on storage container of the present invention in the measuring instrument and each analytical equipment can be taken out automatically.The most important thing is in this respect to need correctly to make storage container with respect to the building blocks of function of measuring instrument particularly with respect to the position of plunger, in order that can take analytical equipment away.Therefore in a preferred embodiment, contain a centre bore, can engage the pilot pin of a coupling of measuring instrument in it according to storage container of the present invention.In this external this hole or leave this hole a recess or a gear ring can be arranged, can engage the corresponding driving device of measuring instrument in it in order that make storage container move to a favourable extraction position.
In corresponding measuring instrument, there is a pilot pin to be bonded in the centre bore of storage container, storage container remained on the tram so that take out analytical equipment.Can a driving gear wheel rim be set on the edge of centre bore in the time of for example in storage container is used in measuring instrument and engage a correspondingly configured coupling part within it, by means of this mechanism, storage container just can rotate in measuring instrument.The rotation of storage container in measuring instrument can turn on the corresponding position that limits in advance storage container, and test element just can take out in measuring instrument by means of plunger like this, and test element can be used for measuring process.
Another themes as the system of an inventory analysis device the present invention, and this system contains one according to storage container of the present invention and two or several analytical equipments.
As mentioned above, system of the present invention contains one according to storage container of the present invention.Have at least two to be preferably 10 to 20 analytical equipments in storage container, each device all is sealed in the cell separately.The test element that analytical equipment preferably is used for analyzing liquid is diagnostic test strip or lancet for example, and test element is the most suitable.Certainly the analytical equipment that also may admit several versions according to the present invention is test element and perverse blood pin for example, and each device all is received within separately the cell.
System of the present invention in addition can comprise a small and exquisite measuring instrument, and this instrument can will keep together according to storage container of the present invention and the analytical equipment that is preferably test element that is included in the container, and can take analytical equipment away from storage container.Analytical equipment can rely on measuring instrument to carry out required analysis in this process.
The last system that can be used to the inventory analysis device that themes as of the present invention, this system contain one or several according to storage container of the present invention, have two or several analytical equipments in each storage container, and storage container are comprised in the container.
In order to increase protection to analytical equipment and storage container of the present invention; make them not be subjected to the influence of hostile environment; particularly moisture, light and mechanical stress can be packaged in them in the container that is enclosed in the outside, for example the metal tube or the plastic tube of an available block sealing.This container that surrounds storage container preferably has other drier, can increase the storage stability of analytical equipment like this.
Advantage of the present invention may be summarized as follows:
Analytical equipment is fixed in the cell of storage container and can protects sealed foil that they are not subjected to unexpectedly, as the influence of the mechanical stress that when dropping, colliding or shaking, produced.
Analytical equipment is fixed in the cell of storage container and can causes the correct location of analytical equipment, thereby can analytical equipment be released outside the cell by plunger with respect to plunger.When releasing analytical equipment outside the storage container, can prevent that plunger from sliding past analytical equipment like this.
Analytical equipment is fixed in the cell of storage container also guiding analytical equipment can be outside analytical equipment is pushed out into storage container the time.The risk of analytical equipment run-off the straight just can reduce in this process like this.
Because two relative holes are designed to different sizes preferably on the cell, therefore only can penetrate by analyzed device at the sealed foil of a side, like this when container is dropped, is collided or shaken, just can not be and dangerous situation takes place at the sealed foil that can not analyzed device penetrates of cell opposite side because of the impact of the inclusion of cell.Make in addition and can be simplified, can be sealed in an operation work step because contain two surfaces in two holes of cell.
When storage container is placed in the plane in order to prevent that paper tinsel is damaged, surface according to the sealed paper tinsels sealing of those of storage container of the present invention has particular design, and this particular design is exactly to be provided with protuberance from the teeth outwards and/or to make the surface become top downward taper shape.
The sealed foil of protection also helps to protect the analytical equipment in the cell of storage container.
Can make at an easy rate with the injection molding method of moulding according to the main body of storage container of the present invention in addition.
The present invention will further illustrate with following accompanying drawing.
Fig. 1 is the side view according to a preferred embodiment of storage container of the present invention.
Fig. 2 is the top view of summary of the circular basal plane (lid) of the storage container among Fig. 1.
Fig. 3 is the top view of summary of the circular basal plane (end) of the storage container among Fig. 1.
Fig. 4 is the longitudinal sectional drawing by the storage container among Fig. 1.
Fig. 5 is the transverse cross-sectional view by the storage container among Fig. 1.
Fig. 6 is the part enlarged drawing of the summary of the test element cell in the top view of Fig. 2.
Fig. 7 is for by the longitudinal sectional drawing according to the summary of another excellent embodiment of storage container of the present invention.
Fig. 8 is that storage container among Fig. 7 is along the part enlarged drawing of the summary in the cross section of B-B ' line by two cells.
Fig. 9 roughly illustrates according to a priority system of the present invention, and this system contains three storage container and containers of storing these containers of using according to test element of the present invention, and its form is that a pipe can be sealed with block.
Label among the figure refers to respectively:
1 storage container
2 test elements
3 test element cells
The top of the conical inclination of 4 storage containers 1
The sealed foil of 5 tops 4
6 protuberances on the conical inclination top 4 of storage container 1
7 drier cells
The flat bottom of 8 storage containers 1
9 protuberances in the flat bottom 8 of storage container 1
10 centre bores and driving ring gear
The sealed foil of 11 bottoms 8
The hole that 12 plungers are used
13 take out the hole that test element is used
14 pack into hole that drier uses
The locular wall of 15 test element cells 3
Narrowing down of 16 test element cells 3
The guide groove that 17 plungers are used
18 rib shape protuberances in locular wall 15
19 lancets
20 lancet cells
21 perverse blood needle bodies
The tubular container of 22 3 storage container 1 usefulness
The block of 23 tubular containers, 22 usefulness
Fig. 1 is the good especially embodiment that a side view illustrates storage container of the present invention (1), and this container is used to the inventory analysis test element in this example.The form of storage container is essentially a cylinder, and it has the top of doing coniform inclination (4) of a circle and one to be essentially flat bottom (8).Top (4) are the limit that can take out test element in this example.Following (8) enter into that limit in the storage container (1) for plunger can penetrate, thereby plunger can be released test element.Shown storage container (1) is preferably made by the injection molded plastic of a rigidity such as polyethylene or polypropylene.The bottom (8) of the top of coniform inclination (4) peace is provided with sealed foil (5,11) and is included in the interior analytical test element of storage container (1) so as to protection.These sealed foils (5,11) can be gluing or be welded on the injection-molded main body of storage container (1).Be provided with protuberance (6,9) in the bottom (8) of storage container (1) and on top (4) as a means of protection sealed foil (5,11).These protuberances are preferably the part of the injection-molded main body of storage container (1).When can being placed in the flat supporting in storage container (1), they guarantee that sealed foil (5,11) is not damaged.Sealed foil (5,11) is provided with the profile that cuts out in the zone that is provided with protuberance (6,9), the not sealed paper tinsel of protuberance (6,9) (5,11) is covered.
Fig. 2 illustrates the top view of top (4) of the coniform inclination of storage container (1).People can be clear that many test element cells (3), radially arrange around the protuberance (6) of the coniform inclination top (4) of storage container (1).The contained hole (13) of taking test element away of test element cell (3) is the side towards coniform inclination top (4) at storage container (1).
Be used for test element is fixed on the inside that the interior facility of test element cell (3) is located at test element cell (3).Being provided with on the one hand the district (16) that narrows down in test element cell (3) can be from the fixing test element in the cell of two offsides.Locular wall (15) at each test element cell (3) is provided with rib shape protuberance (18) on the other hand.Locular wall (15) contains the guide groove (17) of a plunger in addition.
Fig. 3 illustrates the top view of the flat bottom (8) of storage container (1), and as Fig. 2, sealed foil is also taken away.Can see that in this figure hole (14) that hole (12) that plunger is used and filling drier use is all surrounded the driving gear wheel rim around a centre bore (10) and one by protuberance (9).The hole that plunger is used (12) is located at the side towards flat bottom (8) of test element cell (3), can be used to test element is released outside the test element cell (3).The hole that plunger is used (12) is connected on the guide groove (17) of plunger.
Desiccant chamber is communicated with the test element cell by invisible raceway groove among a Fig. 3.The size of raceway groove is selected like this, and each any desiccant particles can not be gone in the test element cell from the drier cell, but the exchange of the gas between two Room must guarantee certainly.
Fig. 4 illustrates the longitudinal profile along the summary of B-B ' line of more excellent storage container (1) among Fig. 2.This section illustrates the position and the shape of test element cell (3), drier cell (7) and centre bore (10) and driven wheel particularly.Section from Fig. 4 can be clear that in addition, and the top of storage container (1) becomes coniform inclination.And also have a test element (2) roughly to be illustrated in order that illustrate its position in test element cell (3).
The sealed foil (11) that the available plunger of test element (2) penetrates in the bottom (8) enters in the hole (12) that is located on the test element cell (3), and it is outer and go up removed from storage container (1) that the sealed foil (5) by top (4) upwards is pushed out into hole (13) again.The position of test element (2) is fixed in the storage container (1) by the rib shape protuberance that narrows down district (16) and be located on test element cell (3) locular wall (15).Can prevent widely that like this sealed foil (5) on the storage container top from inadvertently being pierced through.Sealed foil (11) on storage container (1) following (8) also is protected and makes it does not tested perverse the wearing of element (2); since the hole (12) of going up, in the zone of test element cell (3), having only a plunger to use at the end (8) of storage container (1), and this hole is that test element (2) is intransitable.
The purpose of centre bore (10) is storage container will be remained in the measuring instrument.Be bonded on a pilot pin in the centre bore (10) of corresponding measuring instrument and just storage container (1) can be remained on the tram.Except the function with protection sealed foil (5) on storage container (1) top (4) of top theory, also can be used to the position of stable storage container (1) in measuring instrument at the protuberance (6) on the coniform inclination top (4) of storage container (1).Protuberance (6) for example can engage with the depression or the groove of a coupling.
Bottom at centre bore (10) is provided with a driving gear wheel rim, when storage container (1) is inserted in the measuring instrument, this gear ring can mesh with the part of a correspondingly configured coupling, and by means of this engagement, storage container (1) just can rotate in measuring instrument.Storage container (1) can be by to corresponding precalculated position, and test element can be taken out from measuring instrument and for using in the measuring process by means of plunger.
Among the said good especially embodiment, be provided with a drier cell (7) here, can pass through common drier of hole (14) filling such as silica gel formula molecular sieve on the opposite along diameter of each test element cell (3) according to storage container of the present invention.Each drier cell (7) all is furnished with a directly contiguous test element cell (3) and by a raceway groove connection air of two Room can be exchanged.
Fig. 5 illustrates good especially storage container (1) among Fig. 1 along the cross section of A-A ' line.This figure is clearly shown that the rib shape protuberance (18) that the locular wall (15) of test element cell (3) is interior especially.Each test element cell (3) is provided with three such protuberances.
Fig. 6 is an enlarged detailed of test element cell shown in Figure 2 (3), and one of them test element (2) is fixed on its position by means of the protuberance of the rib shape in test element cell (3) locular wall (15) (18).This rib shape protuberance can guarantee to make test element (2) slight curving and on the basis of this bending strain this element is fixed in the test element cell (3).Narrow down (16) of test element cell (3) are used for further making test element (2) fixing.Test element (2) is inserted in the cell (3) just test element (2) can be installed in the test element cell (3).
Fig. 7 illustrates the longitudinal profile according to the summary of another preferred embodiment of storage container of the present invention.Different with former described embodiment, the perverse blood pin (19) that comprises embodiment illustrated in fig. 7 is as analytical equipment, and it is accommodated in the lancet cell (20).Lancet body (21) part that perverse blood pin (19) is made by plastics surrounds.
As shown in Figure 8, according to storage container of the present invention (1) perverse blood pin cell (20) can be arranged also except test element cell (3).Test element cell (3) and the homotaxis of drier cell (7) on geometry that test element cell (3) and perverse blood pin cell (20) can illustrate with Fig. 5 as an example in the arrangement on the geometry.In addition except test element cell (3) and lancet cell (20), also may provide the drier cell on principle, lancet cell (20) for example under any circumstance all can exchange gas by a raceway groove and a test element cell (3) contact at that time.But may in good especially embodiment shown in Figure 8, not establish drier cell separately in addition yet.For example may make the inwall of test element cell (3) with the plastics that contain drier, also may make perverse blood needle body (21) with the plastics that contain drier.Must under any circumstance can both for example connect raceway groove by one between test element cell (3) and perverse blood pin cell (20) under latter event exchanges gas.
Fig. 9 roughly illustrates according to a preferential system of the present invention, and this system is by forming according to the tubular container (22) of three more excellent storage containers of the present invention and an available block (23) sealing.System shown in Figure 9 for example is used in storage and protects storage container of the present invention (1) when being transported to ultimate user.Tubular container (22) is preferably made by impermeable plastics stable, lightweight or metal such as polyethylene or polypropylene or aluminium.Block (23) is preferably also used a kind of manufacturing in the said material.In graphic form block (23) just is pressed into pipe (22), come so closely to seal.Certainly also available screw lid of this pipe (22) or hinged closure seal.Other drier can be arranged in the tubular container (22) or be received in the bottom or be received in the block (23), so as to the stable test element that is included in the storage container.

Claims (12)

1. the storage container (1) that is used for pocket measuring instrument, this storage container is made by rigid material, for two or several analytical equipments (2) use, contain several independent cells (3), the multipotency of each cell is admitted an analytical equipment (2), wherein, these cells are each other by well-regulated geometric arrangements, each cell (3) has at least two relative holes (12,13), each hole is all sealed by a paper tinsel, and each cell (3) has and can be used to the fixedly facility of the position of cell (3) inner analysis device (2), and this analytical equipment (2) is indoor by slight curvature at this, thereby is fixed on its position by means of the bending stress that is produced.
2. according to the storage container of claim 1, it is characterized by, the part of cell narrows down and is used as the fixedly facility of analytical equipment.
3. according to the storage container of claim 2, it is characterized by, cell has one or several prominent protuberances on indoor locular wall, and cell is narrowed down.
4. according to each storage container among the claim 1-3, it is characterized by, analytical equipment can only be by in each at least two indoor hole.
5. 4 storage container as requested is characterized by, and can not allow a plunger pass through for one at least two holes of each cell that analytical equipment passed through, so plunger can be released analytical equipment from storage container.
6. according to the storage container of claim 5, it is characterized by, each cell contains the guide groove of a plunger.
7. according to each storage container among the claim 1-3, it is characterized by, some protuberances are arranged on the surface with the paper tinsel sealing of storage container, when this storage container was positioned in the flat supporting, these protuberances can prevent that paper tinsel and the direct of supporting from contacting.
8. be used for the device of inventory analysis device, contain according to each storage container and pocket measuring instrument among the claim 1-3 with two or several analytical equipments.
9. according to the device of claim 8, it is characterized by, described analytical equipment is the test element that is used for analyzing liquid.
10. according to the device of claim 9, it is characterized by, also contain a measuring instrument in addition, this measuring instrument is suitable for being used for keeping one or several according to each storage container in the claim 1 to 3.
11. be used for the device of inventory analysis device, contain one or several according to each storage container in the claim 1 to 7, each storage container has two or several analytical equipments, and these storage containers all are comprised in the container.
12. the device according to claim 11 is characterized by, the described container that comprises these storage containers contains a kind of drier.
CNB991050126A 1998-04-24 1999-04-23 Storage container for analysis apparatus Expired - Lifetime CN100467127C (en)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
DE19818359 1998-04-24
DE19818359.3 1998-04-24
DE19854316.6 1998-11-25

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KR100393517B1 (en) * 2000-12-14 2003-08-02 학교법인 인하학원 Incubator
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EP2398388B1 (en) * 2009-02-19 2020-04-08 Roche Diabetes Care GmbH Compact storage of auxiliary analytical devices in a cartridge
WO2012140027A1 (en) * 2011-04-12 2012-10-18 Roche Diagnostics Gmbh Analytical aid
CN105667852B (en) * 2014-11-20 2019-04-05 绍兴普施康生物科技有限公司 The pre-packaged device of reagent
CN111561568B (en) * 2020-02-27 2021-11-23 重庆交通大学 Undisturbed soil sample sealing device based on wax sealing method and sealing method thereof

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CN105662438A (en) * 2010-12-27 2016-06-15 霍夫曼-拉罗奇有限公司 Container made from composite of aluminium foil and polymer and used for analytical aids, and method for producing container
CN105662438B (en) * 2010-12-27 2019-04-12 霍夫曼-拉罗奇有限公司 For analyzing the container and preparation method thereof of auxiliary device made of aluminium foil-polymer composites

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CN101497055A (en) 2009-08-05
KR19990083634A (en) 1999-11-25
KR100706007B1 (en) 2007-04-11
CN101497055B (en) 2011-07-13
HK1135935A1 (en) 2010-06-18
HK1024198A1 (en) 2000-10-05
CN1243041A (en) 2000-02-02
JP2009198521A (en) 2009-09-03

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