CN101084846B - Double-layer weaving polyester artificial vessel - Google Patents
Double-layer weaving polyester artificial vessel Download PDFInfo
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- CN101084846B CN101084846B CN200710087099A CN200710087099A CN101084846B CN 101084846 B CN101084846 B CN 101084846B CN 200710087099 A CN200710087099 A CN 200710087099A CN 200710087099 A CN200710087099 A CN 200710087099A CN 101084846 B CN101084846 B CN 101084846B
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- blood vessel
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Abstract
Double layered weaving artificial blood vessel made of terylen fiber can provide good suturing performance and promote affinity, adhesion and intrusive growth of receptor tissue. The artificial bloodvessel is compact enough, has low porosity thereby exempting blood pre-coagulation in operation. The artificial blood vessel is prepared from 5/2 filling face soleil weave as inner wall of blood vessel and 4/4 huckaback weave as outer wall of blood vessel by combine weaving into double-layer structure with combination of soleil weave and tabby as inner layer and huckaback weave as outer layer.
Description
Technical field
The present invention relates to the medical artificial organ field, especially a kind of manufacture method of implanting intravital artificial blood vessel of animal or human and artificial blood vessel.
Background technology
Artificial blood vessel extensively applies to surgical field, and artificial blood vessel is used to substitute the lesion vessels from body, perhaps implants as vascular bypass when from the body angiemphraxis, or set up new blood vessel path in reconstructing blood vessel.
Using maximum artificial blood vessels to be the fabric prosthese, can be woven, knitting or velvet.The normally woven type of previous use, knitting subsequently prosthese is considered to be better than woven prosthese in many aspects.Especially ascribe knitting high porosity to, softness, the good and inwall floss fiber promotion blood vessel endothelium healing of elasticity promptly promotes the growth of tissue.Yet the knit type artificial blood vessel endothelialization of clinical discovery implant into body is more much lower than the extent of growth of estimating.Other some advantages that ascribe knit type to are not proved yet.
The woven blood vessel also possesses some the aspect characteristic that is better than the knit type blood vessel.Porosity after its braiding is lower than the knit type blood vessel prosthesis, and the even structure unanimity, the neat homogeneous of hole.When woven, by the mechanical mode tight compression, make that hole is very little between the tram.Under some situation, especially implant when artificial blood vessel and used in the patient body of anticoagulant, then require the artificial blood vessel tube wall not leak blood, woven blood vessel prosthesis then meets the requirements.
Since the sixties in last century, " weaving polyester artificial vascular " is widely used in clinical.This more knitting vascular tissue of series blood vessel Stability Analysis of Structures.The 1/1 plain weave systems of knitting (as Fig. 1) that adopt more, not oozing of blood or seldom oozing of blood when its clinical advantages is operation.Its shortcoming is that interlacing point is too tight, and the back tissue that implants is difficult for growing into, and the easy calcification of tube wall, generation degenerative change and operation stitching inserting needle be hard (stinging pin).The lint type artificial blood vessel of the eighties development adopts the satin weave system of knitting (as Fig. 2), and its structure organization point is few, and is floating long through tram.But because it is big through the tram span, thereby tube wall gap hole is big, transplant back growth healing and improve, but oozing of blood is too big during operation, and clinical practice is restricted.The nineties is developed into through 1/1 plain weave that improves abroad or changes plain weave such as rib weave, and it is floating long that outer wall covers warp, and again through the artificial blood vessel of biological coating, the oozing of blood and be easy to sew up of performing the operation not is advanced artificial blood vessel.But it is thinner that its defective is a tube wall, and powerful not enough, acupuncture has pin hole phenomenon etc.
(the patent No.: 03112871.8) Fa Ming " inwall aptychus type woven blood vessel and manufacture method thereof " such as Hua Feng, (patent No.: both all belong to woven type dacron-made artificial blood vessel to " the strengthening the satin weave dacron-made artificial blood vessel " of 03141471.0) inventing to Feng Yun etc., the former has improved the problem of blood flow eddy current in the blood vessel, and the latter strengthens the satin weave terylene can play promotion vessel outer wall tissue adhesion growth.But in fact, zoopery shows that the oozing of blood amount was big when both implanted, and still needs the preceding pre-blood coagulation operation of art, and can not promote the growth of blood vessel endothelialization.Therefore invent a kind of tube wall oozing of blood in the art that really can reduce, can promote blood vessel wall outside receptor tissue to adhere to intyrusive again, the artificial blood vessel of inboard endothelialization is the problem that solution is needed in the medical artificial organ field badly.
Summary of the invention
What synthetic vascular prosthesis material of the present invention adopted is to be convenient to woven fiber or yarn, and preferably tissue intersolubility is good, the polyester material of stable physical property (polyester), the especially Dacron of Dupont company.But any suitable fiber or yarn also can be used as substitute.In addition, scope of the present invention comprises uniting and uses different fibers.
Adhere to intyrusive for ease of tissue, the artificial blood vessel outer wall adopts 4/4 huckaback weave to constitute, and forms the fluffy hole of multifilament and promotes receptor tissue to adhere to, and invades the hole growth.
For avoiding influencing in the tube chamber blood flow and promoting the endothelialization process, inboard yarn adopts the weave of satin weave in conjunction with plain weave.
Exempt pre-blood coagulation operation in the art for reducing artificial blood vessel prosthese porosity, the present invention adopts 5/2 filling face to strengthen satin weave and two kinds of fabric tissues of 4/4 huckaback weave are united " double-layer weaving polyester artificial vascular " that the system of knitting forms tool double wall structure, has solved the previously defective of woven blood vessel's existence.Satin weave is compared with plain weave, in equal area, can increase longitude and latitude silk thread number, make tube wall abundant, third dimension, concave-convex sense are arranged, both increased tube wall antiknock power, avoid acupuncture pin hole phenomenon, postoperative oozing of blood, be easy to the inserting needle of performing the operation again, and the intyrusive that its high-permeability very helps organizing.The artificial blood vessel outer wall of 4/4 huckaback weave covers the floating long organizine that one deck has certain span, be formed with the fluffy hole of multifilament of certain span, after can making in the artificial blood vessel transplant like this, both reduced oozing out of blood, exempt pre-blood coagulation operation in the art, promote receptor tissue to adhere to blood vessel wall and intyrusive again.Blood vessel peripheral cells tissue is grown into, is bred, and delay is healed well thereby artificial blood vessel is grown to the inwall that suitable permeability is arranged.
Thus, purpose of the present invention provides a kind of method for preparing the compact double layer woven fabric, and this material can make receptor tissue adhere to, and keeps minimum porosity guaranteeing to organize under the prerequisite of intyrusive.
Another purpose provides a kind of method for preparing the compact double layer woven blood vessel, and the material of blood vessel prosthesis can make tissue adhere to growth.
Further purpose of the present invention is a kind of compact double layer woven blood vessel of invention, adopt 4/4 huckaback weave in the blood vessel prosthesis outside, inboard satin weave and plain weave are used in combination, and make blood vessel prosthesis provide tissue to adhere to and invade under the prerequisite of growth fast, keep low porosity to exempt in the art blood coagulation in advance and operate.
Other purposes of the present invention and benefit part are apparent, and part is by specific embodiment explanation.Invention scope illustrates in the claims.
Description of drawings
Fig. 1 .1/1 plain weave figure
Fig. 2 .5/2 satin organization charts
Fig. 3 .5/2 filling face is strengthened satin weave figure
The figure of Fig. 4 .4/4 huckaback weave
Fig. 5. huckaback weave's section of structure
The specific embodiment
The present invention has adopted in the satin weave and to have strengthened satin weave (as Fig. 3) and 4/4 huckaback weave (as Fig. 4) through the floating long 5/2 the shortest filling face of tram and unite to knit and make double-decker, the big defective of artificial blood vessel oozing of blood amount before having overcome, and can promote vessel outer wall receptor tissue to adhere to intyrusive, inwall endothelialization process.Promoted the clinical practice index of artificial blood vessel comprehensively.
5/2 filling face that the present invention adopts is strengthened satin weave (as Fig. 3), and its organizine is two floating three heavy, and promptly organizine promotes secondary, and two trams are arranged below; Organizine sinks three times, and three trams are arranged above.
The present invention be three trams that make two trams of sinking and come-up draw close and close, overlapping.With this understanding, its interlacing point is also very not tight, so operation stitching is easy to inserting needle.Since silk thread and close overlappingly, then the organizine number increases, and has both increased intensity, and antiknock power is strengthened, and has thickened tube wall again, makes tube wall careful, avoids acupuncture to leave the phenomenon of pin hole, effectively prevents the prognostic oozing of blood.Because its interlacing point is not tight, silk thread also closes overlapping, fiber fluffy formation porous (micropore), helps growing into of cell tissue.
The present invention simultaneously adopts huckaback weave 4/4 to reinforce plain weave (as Fig. 4), makes tube wall strong, improves the compliance of the permeability and the artificial blood vessel of tube wall.The artificial blood vessel outer wall covers the floating long organizine that one deck has certain span, make outer wall form the gap hole that one deck has certain span, so that behind the artificial blood vessel transplanting human body, the peripheral cells tissue depends on, grows into, derives, and infiltrate into inwall, thereby make artificial blood vessel reach ideal healing effect (Fig. 5: the structural pipe wall profile).
Claims (3)
1. double-layer weaving artificial blood vessel, comprise that strengthening satin weave by 5/2 filling face is that vessel outer wall is united to knit and made double-layered structure's structure as blood vessel and 4/4 huckaback weave, internal layer combines with plain weave for strengthening forging stricture of vagina, skin is a huckaback weave, artificial blood vessel prosthese porosity is low, the braided material histocompatibility is good, internal layer can promote endotheliocyte to adhere to propagation, outer wall energy promotes receptor tissue to adhere to the blood vessel prosthesis growth, the artificial blood vessel inwall adopts five piece two and flies satin, organizine is two floating three heavy, and organizine promotes secondary, and two trams are arranged below; Organizine sinks three times, three trams are arranged above, two trams that sink and three trams of come-up draw close and close, overlapping, cover that the artificial blood vessel tube wall is outer to be crossed over the organizine of tram and cross over that the tram of organizine is floating longly to be 4 interlacing points, make the artificial blood vessel outer wall form the fluffy hole of multifilament.
2. double-layer weaving artificial blood vessel according to claim 1, it is characterized in that satin weave make tube wall abundant, third dimension, concave-convex sense are arranged, avoid the pin hole phenomenon, strengthen the antiknock power of tube wall; The floating length of organizine that some trams are crossed over by 4/4 huckaback weave covers the tube wall skin, is formed with the gap of span, and receptor tissue's adhesion and intrusion are grown into, and makes artificial blood vessel reach good healing effect.
3. according to the described double-layer weaving artificial blood vessel of claim 1, the braided fabric material of internal and external walls is a polyethylene terephthalate.
Priority Applications (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN200710087099A CN101084846B (en) | 2007-03-21 | 2007-03-21 | Double-layer weaving polyester artificial vessel |
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN200710087099A CN101084846B (en) | 2007-03-21 | 2007-03-21 | Double-layer weaving polyester artificial vessel |
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| Publication Number | Publication Date |
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| CN101084846A CN101084846A (en) | 2007-12-12 |
| CN101084846B true CN101084846B (en) | 2010-05-26 |
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| Application Number | Title | Priority Date | Filing Date |
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| CN200710087099A Expired - Fee Related CN101084846B (en) | 2007-03-21 | 2007-03-21 | Double-layer weaving polyester artificial vessel |
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Families Citing this family (5)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN102206888B (en) * | 2011-05-30 | 2012-11-07 | 东华大学 | Integrally formed three-layer woven simulation artificial blood vessel |
| CN108066044B (en) * | 2016-11-07 | 2023-12-29 | 大连科万维医疗科技有限公司 | Adjustable artificial blood vessel with hemorrhage preventing function |
| CN109106468B (en) * | 2018-08-14 | 2023-12-01 | 江苏百优达生命科技有限公司 | Artificial blood vessel structure capable of improving compliance |
| CN113463243B (en) * | 2020-03-11 | 2023-08-18 | 浙江脉通智造科技(集团)有限公司 | Artificial blood vessel and preparation method thereof |
| CN111876884A (en) * | 2020-07-23 | 2020-11-03 | 浙江泰坦股份有限公司 | Zero alignment method for weaving machine |
Citations (4)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US4743251A (en) * | 1983-12-08 | 1988-05-10 | Henry Bocquee | Vein prothesis and method for producing same |
| CN1060023A (en) * | 1990-09-18 | 1992-04-08 | 苏州医学院 | Machine made synthetic small blood vessel |
| CN1522675A (en) * | 2003-02-21 | 2004-08-25 | 无锡莱福纶生物材料有限公司 | Machine knitting artificial blood vessel without pleat in the internal wall, and its making method |
| CN1565394A (en) * | 2003-07-08 | 2005-01-19 | 上海契斯特医疗科技公司 | Reinforced satin dacron-made artificial blood vessel |
-
2007
- 2007-03-21 CN CN200710087099A patent/CN101084846B/en not_active Expired - Fee Related
Patent Citations (4)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US4743251A (en) * | 1983-12-08 | 1988-05-10 | Henry Bocquee | Vein prothesis and method for producing same |
| CN1060023A (en) * | 1990-09-18 | 1992-04-08 | 苏州医学院 | Machine made synthetic small blood vessel |
| CN1522675A (en) * | 2003-02-21 | 2004-08-25 | 无锡莱福纶生物材料有限公司 | Machine knitting artificial blood vessel without pleat in the internal wall, and its making method |
| CN1565394A (en) * | 2003-07-08 | 2005-01-19 | 上海契斯特医疗科技公司 | Reinforced satin dacron-made artificial blood vessel |
Non-Patent Citations (4)
| Title |
|---|
| 凌凯 王璐 费立霞.人造血管的纺织设计与加工技术.上海生物医学工程24 2.2003,24(2),49-52. |
| 凌凯 王璐 费立霞.人造血管的纺织设计与加工技术.上海生物医学工程24 2.2003,24(2),49-52. * |
| 沈国良 唐忠义.机织涤纶人造小血管的实验研究.苏州医学院学报21 2.2001,21(2),139-141. |
| 沈国良 唐忠义.机织涤纶人造小血管的实验研究.苏州医学院学报21 2.2001,21(2),139-141. * |
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